Lysergic Acid Diethylamide (LSD)

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11 Diseases Researched for Lysergic Acid Diethylamide (LSD)
NameACCKFocus
Alcohol Addiction321Locked
Anxiety Disorders312Locked
Anxiety: End of Life110Locked
Cancers: All110Locked
Drug Abuse110Locked
Quality of Life: Poor110Locked
Depression44Locked
Drug Addiction11Locked
Drug Dependence11Locked
Post-Traumatic Stress Disorders (PTSD)11Locked
Substance Dependence11Locked
5 Pharmacological Actions Researched for Lysergic Acid Diethylamide (LSD)
NameACCKFocus
Anti-Anxiety Agents312Locked
Anxiolytic110Locked
Neuroplasticity enhancement110Locked
Antidepressive Agents44Locked
Neuromodulatory11Locked

View the Evidence:
38 Abstracts with Lysergic Acid Diethylamide (LSD) Research

[+]

A meta-analysis of placebo-controlled trials of psychedelic-assisted therapy.Jun 11, 2020

Pubmed Data : J Psychoactive Drugs. 2020 Jun 12:1-11. Epub 2020 Jun 12. PMID: 32529966
Article Published Date : Jun 11, 2020
Study Type : Meta Analysis
Additional Links
Substances : Ayahuasca, Lysergic Acid Diethylamide (LSD), Psilocybin, Psychedelics:All
Diseases : Anxiety, Depression, Post-Traumatic Stress Disorders (PTSD)
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
[+]

A single dose of LSD, in the context of various alcoholism treatment programs, is associated with a decrease in alcohol misuse.Jun 30, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Psychopharmacol. 2012 Jul ;26(7):994-1002. Epub 2012 Mar 8. PMID: 22406913
Article Published Date : Jun 30, 2012
Study Type : Human Study
Additional Links
Substances : Lysergic Acid Diethylamide (LSD)
Diseases : Alcohol Addiction
Additional Keywords : Randomized Controlled Trials As Topic
[+]

Cessation and reduction in alcohol consumption and misuse after psychedelic use.May 13, 2019

Pubmed Data : J Psychopharmacol. 2019 May 14:269881119845793. Epub 2019 May 14. PMID: 31084460
Article Published Date : May 13, 2019
Study Type : Human Study
Additional Links
Substances : Lysergic Acid Diethylamide (LSD)
Diseases : Alcohol Addiction
[+]

Effective connectivity changes in LSD-induced altered states of consciousness in humans.Jan 11, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Proc Natl Acad Sci U S A. 2019 02 12 ;116(7):2743-2748. Epub 2019 Jan 28. PMID: 30692255
Article Published Date : Jan 11, 2019
Study Type : Human Study
Additional Links
Substances : Lysergic Acid Diethylamide (LSD)
Additional Keywords : Altered States Of Consciousness
[+]

Long-lasting subjective effects of LSD in normal subjects.Sep 15, 2017

Pubmed Data : Psychopharmacology (Berl). 2017 Sep 16. Epub 2017 Sep 16. PMID: 28918441
Article Published Date : Sep 15, 2017
Study Type : Human Study
Additional Links
Substances : Lysergic Acid Diethylamide (LSD)
[+]

LSD administered in a medically supervised psychotherapeutic setting can be safe and generate lasting benefits in patients with a life-threatening disease.Dec 31, 2014

Pubmed Data : J Psychopharmacol. 2015 Jan ;29(1):57-68. Epub 2014 Nov 11. PMID: 25389218
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Lysergic Acid Diethylamide (LSD)
Diseases : Anxiety: End of Life, Cancers: All, Quality of Life: Poor
Pharmacological Actions : Anti-Anxiety Agents
Additional Keywords : Significant Treatment Outcome
[+]

LSD can reduce anxiety.Mar 02, 2014

Pubmed Data : J Nerv Ment Dis. 2014 Mar 3. Epub 2014 Mar 3. PMID: 24594678
Article Published Date : Mar 02, 2014
Study Type : Human Study
Additional Links
Substances : Lysergic Acid Diethylamide (LSD)
Diseases : Anxiety Disorders
Pharmacological Actions : Anxiolytic
[+]

LSD induces primary process thinking via activation of 5-HT2A receptors and in relation to disembodiment and blissful state.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2017 ;8:814. Epub 2017 Nov 8. PMID: 29167644
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Substances : Lysergic Acid Diethylamide (LSD)
[+]

LSD selectively expands global connectivity in the brain.Apr 24, 2016

Pubmed Data : Curr Biol. 2016 Apr 25 ;26(8):1043-50. Epub 2016 Apr 13. PMID: 27085214
Article Published Date : Apr 24, 2016
Study Type : Human Study
Additional Links
Substances : Lysergic Acid Diethylamide (LSD)
[+]

LSD-induced entropic brain activity predicts subsequent personality change.May 05, 2016

Pubmed Data : Hum Brain Mapp. 2016 May 6. Epub 2016 May 6. PMID: 27151536
Article Published Date : May 05, 2016
Study Type : Human Study
Additional Links
Substances : Lysergic Acid Diethylamide (LSD)
Pharmacological Actions : Neuroplasticity enhancement
[+]

Microdosing psychedelics: personality, mental health, and creativity differences in microdosers.Jan 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Psychopharmacology (Berl). 2019 Feb ;236(2):731-740. Epub 2019 Jan 2. PMID: 30604183
Article Published Date : Jan 31, 2019
Study Type : Human Study
Additional Links
Substances : Lysergic Acid Diethylamide (LSD), Psilocybin
Diseases : Mood Disorders
[+]

Psilocybin and LSD led to beneficial responses in cluster headaches.Jun 26, 2006

Pubmed Data : Neurology. 2006 Jun 27 ;66(12):1920-2. PMID: 16801660
Article Published Date : Jun 26, 2006
Study Type : Human Study
Additional Links
Substances : Lysergic Acid Diethylamide (LSD), Psilocybin
Diseases : Cluster Headache
Additional Keywords : Significant Treatment Outcome
[+]

Psychedelic microdosing benefits and challenges: an empirical codebook.Jul 09, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Harm Reduct J. 2019 Jul 10 ;16(1):43. Epub 2019 Jul 10. PMID: 31288862
Article Published Date : Jul 09, 2019
Study Type : Human Study
Additional Links
Substances : Lysergic Acid Diethylamide (LSD), Psilocybin, Psychedelics:All
Diseases : Mood Disorders
Additional Keywords : Low-Dose Pharmacology
[+]

These findings reinforce the long-held assumption that psychedelics enhance music-evoked emotion. Aug 10, 2015

Pubmed Data : Psychopharmacology (Berl). 2015 Aug 11. Epub 2015 Aug 11. PMID: 26257162
Article Published Date : Aug 10, 2015
Study Type : Human Study
Additional Links
Substances : Lysergic Acid Diethylamide (LSD)
Therapeutic Actions : Music
[+]

These results suggest that hallucinogens may promote alcohol and other drug abstinence and prosocial behavior in a population with high rates of recidivism.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Psychopharmacol. 2014 Jan ;28(1):62-6. PMID: 24399338
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Substances : Lysergic Acid Diethylamide (LSD), Psilocybin
Diseases : Alcohol Addiction, Drug Abuse
[+]

LSD administered as a single dose reduces alcohol consumption in C57BL/6J mice.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:994. Epub 2018 Aug 31. PMID: 30233372
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Lysergic Acid Diethylamide (LSD)
Diseases : Alcoholism
[+]

Psychedelics promote structural and functional neural plasticity.Jun 11, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Rep. 2018 Jun 12 ;23(11):3170-3182. PMID: 29898390
Article Published Date : Jun 11, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lysergic Acid Diethylamide (LSD), Psychedelics:All
Diseases : Anxiety, Depression
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents, Neurogenesis
[+]

A review of the induction of synaesthesia with chemical agents.Oct 16, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Psychol. 2013 Oct 17 ;4:753. Epub 2013 Oct 17. PMID: 24146659
Article Published Date : Oct 16, 2013
Study Type : Review
Additional Links
Substances : Ayahuasca, Lysergic Acid Diethylamide (LSD), Salvia divinorum
Additional Keywords : Synesthesia
[+]

Acute effects of lysergic acid diethylamide (LSD) on resting brain function.Sep 22, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Swiss Med Wkly. 2019 Sep 23 ;149:w20124. Epub 2019 Sep 30. PMID: 31568558
Article Published Date : Sep 22, 2019
Study Type : Review
Additional Links
Substances : Lysergic Acid Diethylamide (LSD)
[+]

Ayahuasca, psilocybin and LSD may be useful tools for the treatment of drug dependence, and anxiety and mood disorders.May 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ther Adv Psychopharmacol. 2016 Jun ;6(3):193-213. Epub 2016 Mar 18. PMID: 27354908
Article Published Date : May 31, 2016
Study Type : Review
Additional Links
Substances : Ayahuasca, Lysergic Acid Diethylamide (LSD), Psilocybin
Diseases : Anxiety Disorders, Depression, Drug Dependence
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
[+]

Classic psychedelics: An integrative review of epidemiology, therapeutics, mystical experience, and brain network function.Apr 30, 2019

Pubmed Data : Pharmacol Ther. 2019 May ;197:83-102. Epub 2018 Dec 4. PMID: 30521880
Article Published Date : Apr 30, 2019
Study Type : Review
Additional Links
Substances : Lysergic Acid Diethylamide (LSD), Psilocybin, Psychedelics:All
Diseases : Alcohol Addiction, Anxiety: End of Life, Depression
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
Additional Keywords : Spiritual Experiences
[+]

Classical hallucinogens alter the functioning of the serotonergic system which has long been implicated in anxiety and depressive disorders.Jul 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ther Adv Psychopharmacol. 2014 Aug ;4(4):156-69. PMID: 25083275
Article Published Date : Jul 31, 2014
Study Type : Review
Additional Links
Substances : Lysergic Acid Diethylamide (LSD), Psilocybin
Diseases : Anxiety Disorders, Depression
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
[+]

Embedding existential psychology within psychedelic science: reduced death anxiety as a mediator of the therapeutic effects of psychedelics.Nov 28, 2019

Pubmed Data : Psychopharmacology (Berl). 2019 Nov 29. Epub 2019 Nov 29. PMID: 31784805
Article Published Date : Nov 28, 2019
Study Type : Review
Additional Links
Substances : Lysergic Acid Diethylamide (LSD), Psilocybin, Psychedelics:All
Diseases : Anxiety: End of Life
Pharmacological Actions : Anti-Anxiety Agents
[+]

Experience of music used with psychedelic therapy: a rapid review and implications.Mar 29, 2020

Pubmed Data : J Music Ther. 2020 Mar 30. Epub 2020 Mar 30. PMID: 32227084
Article Published Date : Mar 29, 2020
Study Type : Review
Additional Links
Substances : Ayahuasca, Lysergic Acid Diethylamide (LSD), Psilocybin, Psychedelics:All
Therapeutic Actions : Music
[+]

From Hofmann to the Haight Ashbury, and into the future: the past and potential of lysergic acid diethlyamide.Dec 31, 2013

Pubmed Data : J Psychoactive Drugs. 2014 Jan-Mar;46(1):3-10. PMID: 24830180
Article Published Date : Dec 31, 2013
Study Type : Review
Additional Links
Substances : Lysergic Acid Diethylamide (LSD)
Diseases : Alcohol Addiction, Drug Addiction, Post-Traumatic Stress Disorders (PTSD)
[+]

Hallucinogens increase introspection and positive mood by modulating brain activity in the fronto-temporo-parieto-occipital cortex.Nov 30, 2016

Pubmed Data : Neurosci Biobehav Rev. 2016 Dec ;71:715-728. Epub 2016 Oct 31. PMID: 27810345
Article Published Date : Nov 30, 2016
Study Type : Review
Additional Links
Substances : Ayahuasca, Lysergic Acid Diethylamide (LSD), Psilocybin, Psychedelics:All
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]

LSD and psilocybin may be beneficial for depression and anxiety associated with distress in life-threatening diseases.May 02, 2018

Pubmed Data : Pain Manag. 2018 May 3. Epub 2018 May 3. PMID: 29722608
Article Published Date : May 02, 2018
Study Type : Review
Additional Links
Substances : Lysergic Acid Diethylamide (LSD), Psilocybin
Diseases : Anxiety, Cancers: All, Depression
[+]

LSD in this model can be considered antidepressant-like, and discuss it in terms of a re-balance of hippocampal 5-HT2/5-HT1A signalling.Apr 29, 2014

Pubmed Data : J Psychopharmacol. 2014 Apr 30 ;28(6):545-552. Epub 2014 Apr 30. PMID: 24785760
Article Published Date : Apr 29, 2014
Study Type : Review
Additional Links
Substances : Lysergic Acid Diethylamide (LSD)
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]

Over 30 million psychedelic users in the United States.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : F1000Res. 2013 ;2:98. Epub 2013 Mar 28. PMID: 24627778
Article Published Date : Dec 31, 2012
Study Type : Review
Additional Links
Substances : Lysergic Acid Diethylamide (LSD)
[+]

Psychedelic drugs-a new era in 
psychiatry?
Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dialogues Clin Neurosci. 2019 ;21(2):139-147. PMID: 31636488
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Lysergic Acid Diethylamide (LSD), Psychedelics:All
Diseases : Anxiety, Depression, Drug Addiction, Post-Traumatic Stress Disorders (PTSD)
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
[+]

Psychedelic treatment of functional neurological disorder: a systematic reviewDec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ther Adv Psychopharmacol. 2020 ;10:2045125320912125. Epub 2020 May 11. PMID: 32435447
Article Published Date : Dec 31, 2019
Study Type : Review
Additional Links
Substances : Lysergic Acid Diethylamide (LSD), Psilocybin, Psychedelics:All
Diseases : Neurological Conditions
Pharmacological Actions : Neuroprotective Agents
[+]

Psychedelics and immunomodulation: novel approaches and therapeutic opportunities.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2015 ;6:358. Epub 2015 Jul 14. PMID: 26236313
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Lysergic Acid Diethylamide (LSD), Psychedelics:All
Diseases : Alzheimer's Disease, Atherosclerosis, Depression, Inflammation, Multiple Sclerosis, Rheumatoid Arthritis, Schizophrenia
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory
[+]

Psychedelics could be effective in the treatment of mood, anxiety, and substance use disorders.Jun 03, 2018

Pubmed Data : ACS Chem Neurosci. 2018 Jun 4. Epub 2018 Jun 4. PMID: 29863323
Article Published Date : Jun 03, 2018
Study Type : Review
Additional Links
Substances : Ayahuasca, Lysergic Acid Diethylamide (LSD), Psilocybin
Diseases : Anxiety, Mood Disorders, Substance Abuse
Pharmacological Actions : Anti-Anxiety Agents
[+]

Psychedelics in the treatment of PTSD.Dec 31, 2019

Pubmed Data : Tijdschr Psychiatr. 2020 ;62(8):640-649. PMID: 32816292
Article Published Date : Dec 31, 2019
Study Type : Review
Additional Links
Substances : Lysergic Acid Diethylamide (LSD), Psilocybin
Diseases : Post-Traumatic Stress Disorders (PTSD)
[+]

The effects of hallucinogens on gene expression.Dec 31, 2017

Pubmed Data : Curr Top Behav Neurosci. 2018 ;36:137-158. PMID: 28677095
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Substances : Lysergic Acid Diethylamide (LSD), Psilocybin, Psychedelics:All
Diseases : Anxiety, Depression
Additional Keywords : Gene Expression Regulation
[+]

Therapeutic use of classic psychedelics to treat cancer-related psychiatric distress.Aug 12, 2018

Pubmed Data : Int Rev Psychiatry. 2018 Aug 13:1-14. Epub 2018 Aug 13. PMID: 30102082
Article Published Date : Aug 12, 2018
Study Type : Review
Additional Links
Substances : Lysergic Acid Diethylamide (LSD), Psilocybin
Diseases : Cancers: All, Depression
[+]

This paper reviews studies evaluating the use of LSD, peyote, ibogaine and ayahuasca in the treatment of dependencies and the possible mechanisms underlying the indications of effectiveness.Dec 31, 2013

Pubmed Data : Curr Drug Abuse Rev. 2014 ;7(2):101-16. PMID: 25563446
Article Published Date : Dec 31, 2013
Study Type : Review
Additional Links
Substances : Ayahuasca, Lysergic Acid Diethylamide (LSD), Psychedelics:All
Diseases : Substance Dependence
Pharmacological Actions : Neuromodulatory
[+]

This reviews the pharmacology of psychedelic drugs and the therapeutic potentials of these fascinating compounds in mood disorders.Dec 31, 2017

Pubmed Data : Prog Brain Res. 2018 ;242:69-96. Epub 2018 Aug 31. PMID: 30471683
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Substances : Lysergic Acid Diethylamide (LSD), Psilocybin
Diseases : Depression, Mood Disorders
Pharmacological Actions : Antidepressive Agents

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