Maitake Mushroom

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43 Diseases Researched for Maitake Mushroom
NameACCKFocus
Myelodysplastic Syndromes110Locked
Diabetes Mellitus: Type 236Locked
Insulin Resistance36Locked
Breast Cancer35Locked
Immune Dysregulation: TH1/TH2 imbalance35Locked
Liver Cancer35Locked
Colon Cancer24Locked
Myelotoxicity24Locked
Chemotherapy-Induced Toxicity23Locked
Chemotherapy-Induced Toxicity: Cisplatin23Locked
Oxidative Stress23Locked
Prostate Cancer23Locked
Atherosclerosis12Locked
Chemotherapy Induced Myelotoxicity 12Locked
Chemotherapy-Induced Toxicity: Paclitaxel12Locked
Diabetes Mellitus: Type 112Locked
Gastric Cancer22Locked
HSV-112Locked
Hepatic Steatosis12Locked
High Fat Diet12Locked
Hyperinsulinism12Locked
Hypertension12Locked
Hypoglycemia12Locked
Immune Disorders: Low Immune Function12Locked
Listeria Infections12Locked
Liver Disease12Locked
Low Immune Function: Splenic Dysfunction12Locked
Low Immune Function: Thymus Dysfunction12Locked
Neutropenia22Locked
Neutropenia: Chemotherapy Induced22Locked
Neutropenia: Cyclic22Locked
Bladder Cancer11Locked
Cancer Metastasis11Locked
Cancers: Canine11Locked
Chemotherapy-Induced Toxicity: Doxorubicin11Locked
Dry Skin 11Locked
Inflammation11Locked
Influenza A11Locked
Leukopenia: Chemotherapy Induced11Locked
Lung Cancer11Locked
Neutropenia: Severe Congenital11Locked
Organ Transplantation11Locked
Tumors11Locked
34 Pharmacological Actions Researched for Maitake Mushroom
NameACCKFocus
Immunomodulatory924Locked
Antiproliferative 58Locked
Apoptotic68Locked
Hypoglycemic Agents48Locked
Anti-Tumor35Locked
Cell cycle arrest45Locked
Interleukin-12 upregulation35Locked
Alpha-glucosidase inhibitor 24Locked
Chemopreventive24Locked
Hypolipidemic24Locked
Antiviral Agents23Locked
Angiogenesis Inhibitors12Locked
Anti-Bacterial Agents12Locked
Anti-Inflammatory Agents12Locked
Anti-metastatic12Locked
Anticarcinogenic Agents12Locked
Antihypertensive Agents12Locked
Autophagy Up-regulation12Locked
Enzyme Inhibitors12Locked
Hematopoietic22Locked
Hepatoprotective12Locked
Immunostimulatory12Locked
Interferon-gamma (IFN-gamma) inducer12Locked
Interleukin-6 Downregulation12Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor12Locked
Antioxidants11Locked
Bcl-2 protein down-regulation11Locked
Cyclooxygenase 2 Inhibitors11Locked
Cyclooxygenase Inhibitors11Locked
Interferon Inducers11Locked
Interleukin-18 upregulation11Locked
Nitric Oxide Enhancer11Locked
Tumor Necrosis Factor (TNF) Alpha Enhancer11Locked
Tumor Suppressor Protein p53 Upregulation11Locked
Related Topics

Maitake Mushroom is a Sub of the following Topic

View the Evidence:
61 Abstracts with Maitake Mushroom Research

[+]

Meta-analysis on effect of Grifola frondosa polysaccharide in regulating in vivo immunoregulatory function.Nov 30, 2019

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2019 Dec ;44(23):5174-5183. PMID: 32237355
Article Published Date : Nov 30, 2019
Study Type : Meta Analysis
Additional Links
Substances : Maitake Mushroom
Pharmacological Actions : Immunomodulatory
Additional Keywords : Polysaccharides
[+]

A maitake mushroom extract has beneficial immunomodulatory potential in patients with myelodysplastic syndromes.Oct 28, 2014

Pubmed Data : Cancer Immunol Immunother. 2014 Oct 29. Epub 2014 Oct 29. PMID: 25351719
Article Published Date : Oct 28, 2014
Study Type : Human Study
Additional Links
Substances : Maitake Mushroom
Diseases : Myelodysplastic Syndromes
Pharmacological Actions : Immunomodulatory
Additional Keywords : Plant Extracts, Supplementation
[+]

Combined application of Grifola frondosa and vitamin C induced cell apoptosis and autophagy in vitro.Sep 10, 2017

Pubmed Data : Apoptosis. 2017 Sep 11. Epub 2017 Sep 11. PMID: 28894987
Article Published Date : Sep 10, 2017
Study Type : Human In Vitro
Additional Links
Substances : Maitake Mushroom, Vitamin C
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, Autophagy Up-regulation
Additional Keywords : Polysaccharides
[+]

A polysaccharide, extract from Maitake, induces Th-1 dominant responses in cancer-bearing mice. Dec 01, 2002

Pubmed Data : Jpn J Pharmacol. 2002 Dec;90(4):357-60. PMID: 12501013
Article Published Date : Dec 01, 2002
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory
[+]

A selenium enriched polysaccharide from Grifola frondosa significantly inhibited the growth of Heps tumor in vivo.Dec 31, 2015

Pubmed Data : Int J Biol Macromol. 2016 Jan ;82:607-13. Epub 2015 Oct 30. PMID: 26522247
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom, Selenium
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Immunomodulatory
[+]

A water extract of maitake mushroom reduces circulating glucose/insulin concentrations in insulin-resistant mice. Jan 01, 2002

Pubmed Data : Diabetes Obes Metab. 2002 Jan;4(1):43-8. PMID: 11874441
Article Published Date : Jan 01, 2002
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Hyperinsulinism, Insulin Resistance
Pharmacological Actions : Hypoglycemic Agents
[+]

Eringi, Maitake, and Bunashimeji mushrooms prevent atherosclerosis in apolipoprotein E-deficient mice. May 01, 2008

Pubmed Data : Nutr Res. 2008 May;28(5):335-42. PMID: 19083429
Article Published Date : May 01, 2008
Study Type : Animal Study
Additional Links
Substances : Bunashimeji, Eringi mushroom , Maitake Mushroom
Diseases : Atherosclerosis
Pharmacological Actions : Hypolipidemic
[+]

G. frondosa may prevent the further development of NASH by improving the disorder of lipid metabolism in rats.Apr 30, 2015

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2015 May ;40(9):1808-11. PMID: 26323153
Article Published Date : Apr 30, 2015
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Hepatic Steatosis, Liver Disease
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Hypolipidemic, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Griflola frondosa demonstrated the potential as a safe medical food supplement for depression.Nov 30, 2017

Pubmed Data : Pharm Biol. 2017 Dec ;55(1):299-305. PMID: 27937670
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
Additional Keywords : Antidepressive Agents, depression, Maitake Mushroom
[+]

Grifola frondosa extract and ergosterol reduce allergic reactions in an allergy mouse model by suppressing the degranulation of mast cells.Nov 30, 2019

Pubmed Data : Biosci Biotechnol Biochem. 2019 Dec ;83(12):2280-2287. Epub 2019 Aug 14. PMID: 31412751
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Allergies
Pharmacological Actions : Anti-Allergic Agents
Additional Keywords : Plant Extracts
[+]

Grifola frondosa polysaccharides induce breast cancer cell apoptosis.Jul 25, 2017

Pubmed Data : Int J Mol Med. 2017 Jul 26. Epub 2017 Jul 26. PMID: 28765878
Article Published Date : Jul 25, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Apoptotic
Additional Keywords : Polysaccharides
[+]

Hypoglycemic and hypolipidemic activities of Grifola frondosa polysaccharides.Nov 19, 2019

Pubmed Data : Int J Biol Macromol. 2019 Nov 20. Epub 2019 Nov 20. PMID: 31759027
Article Published Date : Nov 19, 2019
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Diabetes Mellitus: Type 2, High Fat Diet
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
[+]

Immunomodulating glucans from Maitake and Shiitake mushrooms strongly stimulated both the cellular and humoral branch of immune reactions.Jan 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Transl Med. 2014 Feb ;2(2):14. PMID: 25332990
Article Published Date : Jan 31, 2014
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom, Shiitake Mushroom
Pharmacological Actions : Immunostimulatory
Additional Keywords : Plant Extracts
[+]

Maitake (G. frondosa) exhibits antitumor activity in colon tumor-bearing mice. Feb 01, 2010

Pubmed Data : J Med Food. 2010 Feb;13(1):20-30. PMID: 20136432
Article Published Date : Feb 01, 2010
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Colon Cancer
Pharmacological Actions : Interferon-gamma (IFN-gamma) inducer, Interleukin-12 upregulation
[+]

Maitake and Bitter Melon (Momordica charantia) contain alpha-glucosidase inhibitors which may have therapeutic value in diabetes type 2. Jul 01, 2002

Pubmed Data : Biosci Biotechnol Biochem. 2002 Jul;66(7):1576-8. PMID: 12224646
Article Published Date : Jul 01, 2002
Study Type : Animal Study
Additional Links
Substances : Bitter Melon, Maitake Mushroom
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Alpha-glucosidase inhibitor , Enzyme Inhibitors
[+]

Maitake beta-glucan enhances therapeutic effect and reduces myelosupression and nephrotoxicity of cisplatin in mice.May 01, 2009

Pubmed Data : Int Immunopharmacol. 2009 May;9(5):620-6. Epub 2009 Feb 26. PMID: 19249389
Article Published Date : May 01, 2009
Study Type : Animal Study
Additional Links
Substances : Beta-glucan, Maitake Mushroom
Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Myelotoxicity
Additional Keywords : Antineoplastic Agents, Drug Side Effect Attenuation
[+]

Maitake beta-glucan induces programmed cell death in human prostatic cancer cells. Jan 01, 2000

Pubmed Data : Boll Soc Ital Biol Sper. 2000 Jan-Feb;76(1-2):1-4. PMID: 10851301
Article Published Date : Jan 01, 2000
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Prostate Cancer
Pharmacological Actions : Apoptotic
[+]

Maitake beta-glucan promotes recovery of leukocytes and myeloid cell function in peripheral blood from paclitaxel hematotoxicity.Feb 06, 2010

Pubmed Data : Cancer Immunol Immunother. 2010 Feb 6. Epub 2010 Feb 6. PMID: 20140432
Article Published Date : Feb 06, 2010
Study Type : Animal Study
Additional Links
Substances : Beta-glucan, Maitake Mushroom
Diseases : Chemotherapy Induced Myelotoxicity , Chemotherapy-Induced Toxicity, Chemotherapy-Induced Toxicity: Paclitaxel, Myelotoxicity
Pharmacological Actions : Chemopreventive
Additional Keywords : Drug Side Effect Attenuation
[+]

Maitake contains a compound known as alpha-glucan which has antidiabetic activity, possibly through reducing insulin resistance. Apr 01, 2007

Pubmed Data : J Pharm Pharmacol. 2007 Apr;59(4):575-82. PMID: 17430642
Article Published Date : Apr 01, 2007
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Hypoglycemic Agents
[+]

Maitake contains a protein with anti-HSV-1 activity. Sep 01, 2007

Pubmed Data : Antiviral Res. 2007 Sep;75(3):250-7. Epub 2007 Apr 17. PMID: 17475344
Article Published Date : Sep 01, 2007
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : HSV-1
Pharmacological Actions : Antiviral Agents
[+]

Maitake D-Fraction enhances antitumor effects and reduces immunosuppression by mitomycin-C in tumor-bearing mice.May 01, 2005

Pubmed Data : Nutrition. 2005 May;21(5):624-9. PMID: 15850970
Article Published Date : May 01, 2005
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Drug-Plant-Vitamin Synergies, Drug Side Effect Attenuation
[+]

Maitake D-Fraction Pro4X prevents breast carcinogenesis, blocks tumor invasiveness, reduces angiogenesis, and increases overall survival.Jul 10, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Med. 2016 Jul 11. Epub 2016 Jul 11. PMID: 27401257
Article Published Date : Jul 10, 2016
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Breast Cancer
Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Anticarcinogenic Agents, Chemopreventive
Additional Keywords : Plant Extracts
[+]

Maitake D-fraction reduces the effective dosage of vancomycin for the treatment of Listeria-infected mice.Dec 01, 2001

Pubmed Data : Jpn J Pharmacol. 2001 Dec;87(4):327-32. PMID: 11829152
Article Published Date : Dec 01, 2001
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Listeria Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Drug Sparing
[+]

Maitake enhances host innate immunity against foreign pathogens without eliciting adverse inflammatory response.Feb 01, 2008

Pubmed Data : J Pharm Pharmacol. 2008 Feb;60(2):237-43. PMID: 18237472
Article Published Date : Feb 01, 2008
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Immune Disorders: Low Immune Function
Pharmacological Actions : Immunomodulatory
Additional Keywords : Cytokine Storm
[+]

Maitake expresses anti-tumor effects by establishing a helper (TH)-1 dominance in mice. Mar 31, 2003

Pubmed Data : Cancer Lett. 2003 Mar 31;192(2):181-7. PMID: 12668282
Article Published Date : Mar 31, 2003
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Anti-Tumor, Immunomodulatory
[+]

Maitake has antihypertensive effects in rats. Aug 01, 2002

Pubmed Data : Mol Cell Biochem. 2002 Aug;237(1-2):129-36. PMID: 12236580
Article Published Date : Aug 01, 2002
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents
[+]

Maitake improves glycemic responses in diabetic rats.Jan 01, 2008

Pubmed Data : Am J Chin Med. 2008;36(2):265-85. PMID: 18457360
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Diabetes Mellitus: Type 1
[+]

Maitake mushroom (SX-fraction) improves insulin sensitivity.Jul 01, 2008

Pubmed Data : Nat Med (Tokyo). 2008 Jul;62(3):284-93. Epub 2008 Feb 13. PMID: 17671829
Article Published Date : Jul 01, 2008
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Insulin Resistance
Pharmacological Actions : Hypoglycemic Agents
[+]

Maitake mushroom and its active fraction inhibit hepatoma growth by inducing autophagy and apoptosis.Mar 23, 2016

Pubmed Data : Exp Biol Med (Maywood). 2016 Mar 24. Epub 2016 Mar 24. PMID: 27013543
Article Published Date : Mar 23, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Up-regulation, Cell cycle arrest
Additional Keywords : Plant Extracts
[+]

Maitake mushroom possesses anti-α-glucosidase activity, and hypoglycemic effect in HFD + STZ-induced hyperglycemic mice.Apr 30, 2015

Pubmed Data : Pharm Biol. 2015 May ;53(5):705-9. Epub 2014 Nov 28. PMID: 25431253
Article Published Date : Apr 30, 2015
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Diabetes Mellitus: Type 2, High Fat Diet, Hypoglycemia, Oxidative Stress
Pharmacological Actions : Alpha-glucosidase inhibitor , Hypoglycemic Agents
[+]

Maitake stimulates immune function through enhancing the thymus index and splenic function in mice. Jan 01, 2003

Pubmed Data : Zhong Yao Cai. 2003 Jan;26(1):31-2. PMID: 12858772
Article Published Date : Jan 01, 2003
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Low Immune Function: Splenic Dysfunction, Low Immune Function: Thymus Dysfunction
Pharmacological Actions : Anti-Tumor, Immunomodulatory
[+]

Mushroom extracts decrease bone resorption and improve bone formation.Dec 31, 2015

Pubmed Data : Int J Med Mushrooms. 2016 ;18(7):559-69. PMID: 27649725
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom, Oyster Mushroom, Shiitake Mushroom
Diseases : Osteoporosis
Pharmacological Actions : Osteogenic, Osteoprotective
Additional Keywords : Plant Extracts
[+]

Soluble β-glucan from Grifola frondosa induces tumor regression in synergy with TLR9 agonist.Nov 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Leukoc Biol. 2015 Dec ;98(6):1015-25. Epub 2015 Aug 21. PMID: 26297795
Article Published Date : Nov 30, 2015
Study Type : Animal Study
Additional Links
Substances : Beta-glucan, Maitake Mushroom
Diseases : Colon Cancer
Pharmacological Actions : Immunomodulatory, Interleukin-12 upregulation
Additional Keywords : Natural Substance/Drug Synergy
[+]

The positive effects of Grifola frondosa heteropolysaccharide on NAFLD and regulation of the gut microbiota.Oct 23, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Oct 24 ;20(21). Epub 2019 Oct 24. PMID: 31653116
Article Published Date : Oct 23, 2019
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Gastrointestinal Agents, Hepatoprotective
[+]

These findings indicated that oral administration of Grifola frondosa polysaccharides could improve memory impairment.Jul 27, 2017

Pubmed Data : Mol Nutr Food Res. 2017 Jul 28. Epub 2017 Jul 28. PMID: 28752930
Article Published Date : Jul 27, 2017
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Aging: Brain , Memory Disorders
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Polysaccharides
[+]

A polysaccharide from Grifola frondosa fruit body induces HT-29 cells apoptosis by PI3K/AKT-MAPKs and NF-κB-pathway.Mar 14, 2020

Pubmed Data : Int J Biol Macromol. 2020 Mar 15 ;147:79-88. Epub 2020 Jan 8. PMID: 31923503
Article Published Date : Mar 14, 2020
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Colorectal Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Polysaccharides
[+]

A review of polysaccharides in Grifola frondosa mushroom and their health promoting properties.Jul 31, 2017

Pubmed Data : Int J Biol Macromol. 2017 Aug ;101:910-921. Epub 2017 Mar 31. PMID: 28366857
Article Published Date : Jul 31, 2017
Study Type : Review
Additional Links
Substances : Maitake Mushroom
Diseases : Cancers: All, Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Immunomodulatory
Additional Keywords : Antioxidants, Cancers: All, Diabetes mellitus: Type 2, Hypoglycemic Agents, Immunomodulatory, Maitake Mushroom, Polysaccharides
[+]

A variety of mushroom inhibit breast cancer cell proliferation. Nov 01, 2010

Pubmed Data : Exp Biol Med (Maywood). 2010 Nov;235(11):1306-14. Epub 2010 Oct 4. PMID: 20921274
Article Published Date : Nov 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Crimini Mushroom, Maitake Mushroom, Oyster Mushroom, Portabella Mushroom, White Button Mushroom
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

An extract of Maitake mushroom reduced the migration and invasion of mammary tumor cells, generating less aggressive cell behaviours.Dec 31, 2016

Pubmed Data : Nutr Cancer. 2017 Jan ;69(1):29-43. Epub 2016 Nov 28. PMID: 27892708
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Breast Cancer
Pharmacological Actions : Anti-metastatic
Additional Keywords : Plant Extracts
[+]

Extracts from medicinal basidiomycetes mushrooms had anti-tumor activity against cancer cell lines. Dec 31, 2015

Pubmed Data : Int J Med Mushrooms. 2016 ;18(11):955-964. PMID: 28008808
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom, Reishi Mushroom, Shiitake Mushroom
Diseases : Kidney Cancer, Laryngeal Cancer, Lung Cancer
Pharmacological Actions : Cytotoxic, Immunomodulatory
[+]

G. frondosa polysaccharide has antiviral activity.Jun 24, 2016

Pubmed Data : Carbohydr Polym. 2016 Jun 25 ;144:382-9. Epub 2015 Dec 30. PMID: 27083830
Article Published Date : Jun 24, 2016
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Enterovirus 71
Pharmacological Actions : Antiviral Agents, Apoptotic
Additional Keywords : Polysaccharides
[+]

Glycoprotein GFG-3a induces apoptosis in human gastric cancer cells.Jan 31, 2016

Pubmed Data : Nutr Cancer. 2016 Feb-Mar;68(2):267-79. PMID: 27040446
Article Published Date : Jan 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Gastric Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Tumor Suppressor Protein p53 Upregulation
[+]

Grifola frondosa and Vitamin C had a synergistic apoptotic effect on SMMC-7721 liver cancer cells. May 04, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Cancer Ther. 2016 May 5. Epub 2016 May 5. PMID: 27151580
Article Published Date : May 04, 2016
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom, Vitamin C
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation
Additional Keywords : Natural Substance Synergy
[+]

Maitake (G. frondosa) enhances phagocytosis of human polymorphonuclear neutrophils (PMN). Apr 19, 2006

Pubmed Data : J Agric Food Chem. 2006 Apr 19;54(8):2906-14. PMID: 16608207
Article Published Date : Apr 19, 2006
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Neutropenia, Neutropenia: Chemotherapy Induced, Neutropenia: Cyclic, Neutropenia: Severe Congenital
[+]

Maitake appears to induce the production of certain factors, including TNF-alpha, which are responsible for the inhibition of viral growth in vitro.Apr 01, 2010

Pubmed Data : Pharm Biol. 2010 Apr;48(4):469-81. PMID: 19051344
Article Published Date : Apr 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Influenza A
Pharmacological Actions : Antiviral Agents, Tumor Necrosis Factor (TNF) Alpha Enhancer
[+]

Maitake beta-glucan MD-fraction enhances bone marrow colony formation and reduces doxorubicin toxicity in vitro.Jan 01, 2004

Pubmed Data : Int Immunopharmacol. 2004 Jan;4(1):91-9. PMID: 14975363
Article Published Date : Jan 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Hematopoietic
Additional Keywords : Colony-Stimulating Factors (CSFs)
[+]

Maitake contains cyclooxygenase inhibitory and antioxidant compounds. Nov 01, 2002

Pubmed Data : Endocr Pract. 2002 Nov-Dec;8(6):417-23. PMID: 12475274
Article Published Date : Nov 01, 2002
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Antioxidants, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors
[+]

Maitake D-fraction (MDF) is a novel inducer for iNOS which contributes at least in part to antitumor activity of MDF.Dec 01, 2001

Pubmed Data : J Exp Clin Cancer Res. 2001 Dec;20(4):591-7. PMID: 11876556
Article Published Date : Dec 01, 2001
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Tumors
Pharmacological Actions : Immunomodulatory, Nitric Oxide Enhancer
[+]

Maitake D-Fraction establishes Th-1 dominance which induces cellular immunity in the population that was Th-2 dominant due to carcinoma.Apr 01, 2002

Pubmed Data : Biol Pharm Bull. 2002 Apr;25(4):536-40. PMID: 11995941
Article Published Date : Apr 01, 2002
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Anti-Tumor, Interferon Inducers, Interleukin-12 upregulation, Interleukin-18 upregulation
[+]

Maitake D-Fraction exhibits synergistic anti-cancer activity with interferon in prostate cancer cells. Jan 01, 2008

Pubmed Data : J Hematol Oncol. 2008;1:25. Epub 2008 Dec 4. PMID: 19055833
Article Published Date : Jan 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Prostate Cancer
Pharmacological Actions : Cell cycle arrest
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Maitake D-fraction has potential growth inhibitory effects in canine cancer cells. Jan 01, 2004

Pubmed Data : Vet Ther. 2004;5(4):263-71. PMID: 15719326
Article Published Date : Jan 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Cancers: Canine
[+]

Maitake D-Fraction inhibit colon, lung and melanoma cell metastasis by activating Natural Killer (NK) cells. Jun 01, 2008

Pubmed Data : Biol Pharm Bull. 2008 Jun;31(6):1104-8. PMID: 18520039
Article Published Date : Jun 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Cancer Metastasis, Lung Cancer
Pharmacological Actions : Immunomodulatory
[+]

Maitake enhances granulopoiesis and mobilization of granulocytes by increasing granulocyte colony-stimulating factor. Jun 30, 2009

Pubmed Data : Int Immunopharmacol. 2009 Jun 30. PMID: 19573626
Article Published Date : Jun 30, 2009
Study Type : Commentary
Additional Links
Substances : Maitake Mushroom
Diseases : Chemotherapy-Induced Toxicity, Chemotherapy-Induced Toxicity: Cisplatin, Leukopenia: Chemotherapy Induced, Neutropenia, Neutropenia: Chemotherapy Induced, Neutropenia: Cyclic
Additional Keywords : Colony-Stimulating Factors (CSFs)
[+]

Maitake induces programmed cell death in gastric cancer cells. Sep 01, 2009

Pubmed Data : Oncol Rep. 2009 Sep;22(3):615-20. PMID: 19639212
Article Published Date : Sep 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Gastric Cancer
Pharmacological Actions : Apoptotic
[+]

Maitake may have a therapeutic role in supporting engraftment in organ transplantation. Mar 01, 2009

Pubmed Data : Exp Biol Med (Maywood). 2009 Mar;234(3):342-53. Epub 2009 Jan 14. PMID: 19144872
Article Published Date : Mar 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Organ Transplantation
Pharmacological Actions : Hematopoietic
[+]

Maitake may have a therapeutic role in the treatment of dry skin. Dec 27, 2002

Pubmed Data : J Biol Chem. 2002 Dec 27;277(52):50341-7. Epub 2002 Oct 16. PMID: 19228191
Article Published Date : Dec 27, 2002
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Dry Skin
[+]

Maitake mushroom d-fraction exhibits a synergistic effect with interferon on inhibiting bladder cancer cells. Sep 04, 2009

Pubmed Data : BJU Int. 2009 Sep 4. Epub 2009 Sep 4. PMID: 19735256
Article Published Date : Sep 04, 2009
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Bladder Cancer
Pharmacological Actions : Cell cycle arrest
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Purification, characterization and immunomodulatory activity of a novel polysaccharide from Grifola frondosa.Jan 20, 2018

Pubmed Data : Int J Biol Macromol. 2018 Jan 21. Epub 2018 Jan 21. PMID: 29395342
Article Published Date : Jan 20, 2018
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Cancers: All
Pharmacological Actions : Chemotherapeutic, Immunomodulatory
Additional Keywords : Polysaccharides
[+]

Structural elucidation and immune-enhancing effects of novel polysaccharide from Grifola frondosa.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2019 ;2019:7528609. Epub 2019 Apr 16. PMID: 31139649
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Pharmacological Actions : Antihypertensive Agents, Hypoglycemic Agents, Immunostimulatory
Additional Keywords : Polysaccharides
[+]

Synergistic immuno-modulatory activity in human macrophages of a medicinal mushroom formulation consisting of Reishi, Shiitake and Maitake.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2019 ;14(11):e0224740. Epub 2019 Nov 7. PMID: 31697749
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom, Reishi Mushroom, Shiitake Mushroom
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Immunomodulatory
Additional Keywords : Natural Substance Synergy
[+]

YM-2A might be a candidate for an oral therapeutic agent in cancer immunotherapy.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(3):e0173621. Epub 2017 Mar 9. PMID: 28278221
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Cancers: All
Pharmacological Actions : Immunomodulatory

Maitake Mushroom Related Articles

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This cool tweak will increase the power of mushrooms to maintain and improve your health!
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Written by Margie King, Health Coach
Although mushrooms get good press as a low-calorie, high fiber, low-cholesterol, low-sodium decoration for your pizza, there is much more to the mushroom story than that. Mushrooms have been valued for their culinary and medicinal properties for thousands of years and ancient cultures associated them with immortality for good reason

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