Mangiferin

Name	AC	CK
Diabetes Mellitus: Type 2	9	33
Athletic Performance	2	20
Inflammation	12	18
Oxidative Stress	10	18
Cancers: All	10	11
Chemically-Induced Liver Damage	5	11
Diabetic Nephropathy	5	10
Insulin Resistance	5	10
Lipopolysaccharide-Induced Toxicity	8	10
Osteoarthritis	6	9
Parkinson's Disease	5	9
Alzheimer's Disease	6	8
Nonalcoholic fatty liver disease (NAFLD)	4	8
Obesity	5	8
Colorectal Cancer	4	7
Mercury Poisoning	3	7
Kidney Damage	3	6
Ovarian Cancer	4	6
Allergies	3	5
Chemotherapy-Induced Toxicity: Cisplatin	3	5
Lung Cancer	4	5
Lung Injury: Acute	3	5
Neuropathic Pain	3	5
Wound Healing	3	5
Arsenic Poisoning	2	4
Cognitive Decline/Dysfunction	2	4
Colitis	2	4
Diabetes: Cardiovascular Illness	2	4
Heart Failure	2	4
High Fat Diet	2	4
Hyperglycemia	3	4
Hyperlipidemia	2	4
Hyperuricemia	2	4
Ischemia	2	4
Liver Fibrosis	2	4
Myocardial Fibrosis	2	4
Neurodegenerative Diseases	4	4
Osteoporosis	3	4
Pulmonary Fibrosis	2	4
Pulmonary Fibrosis: Bleomycin-Induced	2	4
Sepsis	2	4
Allergic Rhinitis	2	3
Breast Cancer	3	3
Carcinoma: Non-Small-Cell Lung	2	3
Colon Cancer	2	3
Depression	2	3
Depression: Postpartum	1	3
Herpes Simplex Virus Type 1	2	3
Liver Cancer	2	3
Metabolic Syndrome X	3	3
Periodontitis	2	3
Stroke	2	3
Tumors	2	3
Acetaminophen (Tylenol) Toxicity	1	2
Acute Myeloid Leukemia	1	2
Advanced Glycation End products (AGE)	2	2
Aging: Heart	1	2
Alcoholic Liver Disease	1	2
Allodynia	1	2
Aluminum Toxicity	1	2
Anaphylaxis	1	2
Aneurysmal subarachnoid hemorrhage (SAH)	1	2
Arteriosclerosis	1	2
Arthritis	1	2
Bone Fractures	1	2
Brain Cancer	2	2
Brain Damage: Hypoxic Ischemic Insult	1	2
Brain Injury: Traumatic	1	2
Brain Ischemia	1	2
Brain: Oxidative Stress	1	2
Breast Cancer: Chemically-Induced	1	2
Cancer Metastasis	1	2
Cardiomyopathy: Hypertrophic	1	2
Cerebral Ischemia	1	2
Cervical Cancer	2	2
Chemotherapy-Induced Toxicity: Cyclophosphamide	1	2
Chronic Pain	1	2
Colon Polyps	1	2
Coronavirus Infection	2	2
Dementia	1	2
Dermatitis	1	2
Diabetes Mellitus: Type 1	2	2
Diabetes Mellitus: Type 1: Prevention	1	2
Diabetes: Kidney Function	1	2
Diabetic Complications	2	2
Drug Toxicity: Methotrexate	1	2
Formaldehyde Toxicity	1	2
Gastric Ulcer	1	2
Gestational Diabetes	1	2
HSV-1	2	2
Huntington Disease	1	2
Hydrogen Peroxide Induced Toxicity	2	2
Hyperalgesia	1	2
Hyperinsulinism	1	2
Hypersensitivity	1	2
Hypertension	1	2
Immune Disorders: Low Immune Function	1	2
Inflammatory Bowel Diseases	1	2
Intervertebral Disk Displacement	1	2
Iron Overload	1	2
Ischemia: Myocardial	1	2
Kidney Damage: Drug-Induced	1	2
Leukemia	2	2
Lipid Peroxidation	1	2
Liver Cirrhosis	1	2
Liver Injury: Ischemia/reperfusion	1	2
Melanoma: Metastasis	1	2
Multiple Myeloma	2	2
Myocardial Infarction	1	2
Myocardial Ischemia	2	2
Oral Cancer	1	2
Pain	1	2
Parasitic Diseases	1	2
Pre-Eclampsia	1	2
Prostate Cancer	2	2
Pruritus	1	2
Radiation Induced Illness	2	2
Renal Fibrosis	1	2
Renal tubulointerstitial fibrosis	1	2
Rheumatoid Arthritis	2	2
Testicular Injury: Chemical/Metal Induced	1	2
Triglycerides: Elevated	1	2
5alpha-dihydrotestosterone (DHT): Elevated Levels/Activity	1	1
Aging	1	1
Air Pollution Linked Toxicity	1	1
Amyotrophic Lateral Sclerosis	1	1
Asthma	1	1
Atherosclerosis	1	1
Atopic Dermatitis	1	1
Bone Diseases	1	1
Brain Inflammation	1	1
Breast Cancer: Triple Negative	1	1
Burkitt Lymphoma	1	1
Cadmium Poisoning	1	1
Candida Infection	1	1
Chemotherapy-Induced Toxicity: Doxorubicin	1	1
Chronic Kidney Disease (CKD)	1	1
Chronic Obstructive Lung Disease	1	1
Dengue	1	1
Diabetic Retinopathy	1	1
Endothelial Dysfunction	1	1
Fibrosarcoma	1	1
Fibrosis	1	1
Fluoride Toxicity	1	1
Fungus Diseases	1	1
Gastric Cancer	1	1
Glioblastoma	1	1
Gram-Negative Bacterial Infections	1	1
Gram-Positive Bacterial Infections	1	1
HIV Infections	1	1
HSV-2	1	1
Hearing Loss	1	1
Heavy Metal Toxicity	1	1
Helicobacter Pylori Infection	1	1
High Sugar Diet	1	1
Hypoglycemia	1	1
Hypoxia	1	1
Infection: Antibiotic Resistant	1	1
Insomnia	1	1
Kidney Diseases	1	1
Kidney Fibrosis	1	1
Leukemia: Acute myelogenous leukemia (AML)	1	1
Liver Damage	1	1
Liver Disease	1	1
Mastitis	1	1
Melanoma: Metastatic	1	1
Memory Disorders	1	1
Mitochondrial Dysfunction	1	1
Mycotoxin Toxicity	1	1
Oral Submucous Fibrosis	1	1
Osteosarcoma	1	1
Promyelocytic leukemia	1	1
Prostatic Hyperplasia: Benign	1	1
Psychiatric Disorders	1	1
Retroviruses	1	1
Smoking	1	1
Staphylococcus aureus infection	1	1

Name	AC	CK
Anti-Inflammatory Agents	73	133
Antioxidants	55	102
Tumor Necrosis Factor (TNF) Alpha Inhibitor	22	40
Hypoglycemic Agents	13	39
NF-kappaB Inhibitor	23	36
Neuroprotective Agents	22	35
Hepatoprotective	18	33
Anti-Apoptotic	15	23
Antiproliferative	18	22
Cardioprotective	13	22
Interleukin-6 Downregulation	14	22
Anticholesteremic Agents	2	21
Renoprotective	11	20
Apoptotic	16	19
Interleukin-1 beta downregulation	12	19
Nrf2 activation	12	18
Anti-metastatic	12	16
Anti-Fibrotic	8	14
Immunomodulatory	9	13
Antiviral Agents	10	11
Chemotherapeutic	9	11
Chemopreventive	6	9
Cyclooxygenase 2 Inhibitors	7	9
Anticarcinogenic Agents	4	8
Matrix metalloproteinase-9 (MMP-9) inhibitor	6	8
Heme oxygenase-1 up-regulation	5	7
Hypolipidemic	5	7
Matrix metalloproteinase-2 (MMP-2) inhibitor	5	7
Analgesics	4	6
Angiogenesis Inhibitors	4	6
Chemoprotective Agents	4	6
Interleukin-18 down-regulation	4	6
Anti-Allergic Agents	3	5
Anti-Bacterial Agents	4	5
Antidepressive Agents	2	5
Antineoplastic Agents	3	5
Chemosensitizer	3	5
Osteoprotective	3	5
Pancreato Protective Agents	3	5
Wnt/β-catenin signaling pathway modulation	3	5
Antinoceceptive	2	4
Cell cycle arrest	3	4
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	2	4
MicroRNA modulator	4	4
Cytoprotective	3	3
Fibroblast growth factor 21 upregulation	1	3
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	3	3
Radioprotective	3	3
Uricosuric Agents	2	3
Angiotensin-Converting Enzyme Inhibitors	1	2
Anti-Glycation Agents	2	2
Anti-Ulcer Agents	1	2
Antifungal Agents	2	2
Antihypertensive Agents	1	2
Antiparasitic Agents	1	2
Autophagy Inhibitors	1	2
Autophagy Up-regulation	2	2
Immunomodulatory: Th17 downregulation	1	2
Immunostimulatory	1	2
Interferon Gamma Reducer	1	2
Malondialdehyde Down-regulation	1	2
NF-E2-Related Factor-2 (Nrf2) Modulator	1	2
Nitric Oxide Enhancer	1	2
STAT3 Inhibitor	2	2
Transforming growth factor beta (TGF-β) inhibitor	1	2
Transforming growth factor beta (TGF-β) upregulation	1	2
Vasoprotective	1	2
Xanthine oxidase inhibitor	1	2
5-alpha reductase inhibitor	1	1
Adiponectin upregulation	1	1
Alpha-glucosidase inhibitor	1	1
Anti-Adipogenic	1	1
Anti-Angiogenic	1	1
Anti-Asthmatic Agents	1	1
Anti-HIV Agents	1	1
Anti-atherogenic	1	1
Anti-pyretic	1	1
Antimicrobial	1	1
Antimutagenic Agents	1	1
Bcl-2 protein down-regulation	1	1
Chelating Agents	1	1
ER beta receptor up-regulation	1	1
Enzyme Inhibitors	1	1
Genoprotective	1	1
Insulin-releasing	1	1
Interleukin-8 downregulation	1	1
Nitric Oxide Inhibitor	1	1
Radiosensitizer	1	1
Tumor Suppressor Protein p53 Upregulation	1	1
Vascular Endothelial Growth Factor Inhibitors	1	1
p300/NF-κB down-regulation	1	1

[+]

Oral administration of mangiferin ameliorates diabetes.Dec 31, 2020

Click here to read the entire abstract

Pubmed Data : Nutr Res. 2021 03 ;87:57-69. Epub 2020 Dec 25. PMID: 33601215

Article Published Date : Dec 31, 2020

Study Type : Meta Analysis, Review

Additional Links

Substances : Mangiferin

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Anti-Inflammatory Agents, Anticholesteremic Agents, Antioxidants, Hypoglycemic Agents

[+]

[+]

Mangiferin alleviates postpartum depression-like behaviors.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2022 ;13:840567. Epub 2022 Jun 3. PMID: 35721155

Article Published Date : Dec 31, 2021

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Mangiferin

Diseases : Depression: Postpartum

Pharmacological Actions : Antidepressive Agents

[+]

Mangiferin ameliorates obesity-associated inflammation and autophagy in high-fat-diet-fed mice.Dec 04, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : J Diet Suppl. 2018 Jul 9:1-17. Epub 2018 Jul 9. PMID: 29985711

Article Published Date : Jul 08, 2018

Study Type : Animal Study

Additional Links

Substances : Mangiferin, Resveratrol

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Hypoglycemic Agents

[+]

Anti-allodynic effect of mangiferin in rats with chronic post-ischemia pain.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2019 Feb 12 ;126:41-55. Epub 2019 Feb 12. PMID: 30769048

Article Published Date : Feb 11, 2019

Study Type : Animal Study

Additional Links

Substances : Mangiferin

Diseases : Arsenic Poisoning

Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation

Problem Substances : Arsenic

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Pharmacother. 2019 Jun 15 ;117:109097. Epub 2019 Jun 15. PMID: 31212128

Article Published Date : Jun 14, 2019

Study Type : Animal Study

Additional Links

Substances : Mangiferin

Diseases : Acetaminophen (Tylenol) Toxicity , Chemically-Induced Liver Damage

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Problem Substances : Acetaminophen, Paracetamol

[+]

Mangiferin ameliorates cardiac fibrosis in D-galactose-induced aging.Feb 28, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Mangiferin inhibits bowel carcinogenesis in male rats.Feb 26, 2001

Click here to read the entire abstract

Pubmed Data : Cancer Lett. 2001 Feb 26;163(2):163-70. PMID: 11165750

Article Published Date : Feb 26, 2001

Study Type : Animal Study

Additional Links

Substances : Mangiferin

Diseases : Colon Cancer, Colon Polyps

Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Chemopreventive

Additional Keywords : Xanthones

[+]

Mangiferin inhibits high-fat diet induced vascular injury via regulation of PTEN/AKT/eNOS pathway.Jun 30, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int Immunopharmacol. 2016 May ;34:220-8. Epub 2016 Mar 9. PMID: 26971225

Article Published Date : Apr 30, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Mangiferin

Diseases : Colitis

Pharmacological Actions : Immunomodulatory: Th17 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Mangiferin may be considered a potential antineoplastic drug for the future treatment of cancer.Mar 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Med Rep. 2016 Apr ;13(4):3423-32. Epub 2016 Feb 29. PMID: 26935347

Click here to read the entire abstract

Pubmed Data : J Cell Mol Med. 2021 Feb 1. Epub 2021 Feb 1. PMID: 33523605

Article Published Date : Jan 31, 2021

Study Type : Animal Study

Additional Links

Substances : Mangiferin

Diseases : Heart Failure, Myocardial Infarction

Pharmacological Actions : Cardioprotective

[+]

Mangiferin promotes osteogenic differentiation and alleviates osteoporosis.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : J Trace Elem Med Biol. 2015 Jul ;31:107-12. Epub 2015 Apr 22. PMID: 26004900

Article Published Date : Jun 30, 2015

Study Type : Animal Study

Additional Links

Substances : Mangiferin

Diseases : Aluminum Toxicity , Brain: Oxidative Stress, Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

Problem Substances : Aluminum Chloride

[+]

Mangiferin protects the streptozotocin-induced oxidative damage to cardiac and renal tissues in rats.Jul 15, 2002

Click here to read the entire abstract

Pubmed Data : Toxicology. 2002 Jul 15;176(3):165-73. PMID: 12093613

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2018 ;9:638. Epub 2018 Jun 18. PMID: 29967581

Article Published Date : Dec 31, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Ellagic Acid, Lignans, Luteolin, Mangiferin

Diseases : Ovarian Cancer

Pharmacological Actions : Anti-metastatic, Antineoplastic Agents, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Pharmaceutics. 2023 May 23 ;15(6). Epub 2023 May 23. PMID: 37376018

Article Published Date : May 22, 2023

Study Type : Animal Study

Additional Links

Substances : Mangiferin

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction, Formaldehyde Toxicity

Pharmacological Actions : Neuroprotective Agents

Problem Substances : Formaldehyde

[+]

The wound-healing effect of mango peel extract on incision wounds.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2022 Jan 1 ;27(1). Epub 2022 Jan 1. PMID: 35011491

Pharmacological Actions : Anti-Inflammatory Agents, Autophagy Up-regulation, Chemotherapeutic

Additional Keywords : Tumor Microenvironment

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : J Biochem Mol Toxicol. 2024 Oct ;38(10):e23849. PMID: 39264833

Article Published Date : Sep 30, 2024

Study Type : In Vitro Study

Additional Links

Substances : Mangiferin

Diseases : Amyotrophic Lateral Sclerosis, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents, Nrf2 activation

[+]

Mangiferin alleviates cisplatin-induced ototoxicity in sensorineural hearing loss.Aug 31, 2024

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Pharmacother. 2024 Sep ;178:117174. Epub 2024 Aug 3. PMID: 39098177

Article Publish Status : This is a free article. Click here to read the complete article.

Mangiferin attenuates mercury chloride induced cytotoxicity and genotoxicity in liver cells.Feb 09, 2011

Click here to read the entire abstract

Pubmed Data : J Biochem Mol Toxicol. 2011 Feb 9. Epub 2011 Feb 9. PMID: 21308892

Article Published Date : Feb 09, 2011

Study Type : In Vitro Study

Additional Links

Substances : Mangiferin

Diseases : Chemically-Induced Liver Damage, Mercury Poisoning

Pharmacological Actions : Hepatoprotective

[+]

Mangiferin attenuates myocardial ischemia-reperfusion injury.Dec 31, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2023 Oct ;31(5):1394-1402. PMID: 37846690

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biofactors. 2016 May 24. Epub 2016 May 24. PMID: 27219011

Article Published Date : May 23, 2016

Study Type : Review

Additional Links

Substances : Mangiferin

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Mangiferin has potent antitumor, immunomodulatory and anti-HIV activity. Nov 01, 2009

Click here to read the entire abstract

Pubmed Data : J Obstet Gynaecol. 2009 Nov;29(8):681-5. PMID: 8957579

Article Publish Status : This is a free article. Click here to read the complete article.

Mangiferin offers protection against deleterious effects of pharmaceuticals, heavy metals, and environmental chemicals.Sep 21, 2020

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2020 Sep 22. Epub 2020 Sep 22. PMID: 32961631

Article Published Date : Sep 21, 2020

Study Type : Review

Additional Links

Substances : Mangiferin

Diseases : Heavy Metal Toxicity

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Chelating Agents

Problem Substances : Heavy Metals

[+]

Mangiferin positively regulates osteoblast differentiation and suppresses osteoclast differentiation.Jul 31, 2017

Click here to read the entire abstract

Pubmed Data : Mol Med Rep. 2017 Aug ;16(2):1328-1332. Epub 2017 Jun 12. PMID: 28627701

Article Published Date : Jul 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Mangiferin

Diseases : Bone Diseases, Osteoarthritis

[+]

Mangiferin potentiates the activity of antifungal agents against fluconazole-resistant Candida.Aug 31, 2024

Click here to read the entire abstract

Pubmed Data : Future Microbiol. 2024 Sep ;19(13):1157-1170. Epub 2024 Jul 16. PMID: 39012219

Click here to read the entire abstract

Pubmed Data : Environ Mol Mutagen. 2005 Jul;46(1):12-21. PMID: 15795888

Article Published Date : Jul 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Mangiferin

Diseases : Radiation Induced Illness

Pharmacological Actions : Antioxidants, Antiproliferative , Genoprotective, Radioprotective

Additional Keywords : Xanthones

[+]

Mangiferin protects mitochondrial function in endothelial cells.May 02, 2017

Click here to read the entire abstract

Pubmed Data : Biochim Biophys Acta. 2017 May 3. Epub 2017 May 3. PMID: 28478227

Article Published Date : May 02, 2017

Study Type : In Vitro Study

Additional Links

Substances : Mangiferin

Diseases : Mitochondrial Dysfunction

[+]

Mangiferin protects osteoblast against oxidative damage.Sep 22, 2017

Click here to read the entire abstract

Pubmed Data : Biochem Biophys Res Commun. 2017 Sep 23 ;491(3):807-813. Epub 2017 Jun 30. PMID: 28669729

Article Published Date : Sep 22, 2017

Study Type : In Vitro Study

Additional Links

Substances : Mangiferin

Diseases : Osteoporosis, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Antioxidants

Additional Keywords : Xanthones

[+]

Mangiferin relieves lipopolysaccharide-induced injury by up-regulating miR-181a via targeting PTEN in ATDC5 cells.Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2016 ;8(7). Epub 2016 Jun 28. PMID: 27367721

Click here to read the entire abstract

Pubmed Data : Pharmacol Res. 2019 Jul 2 ;146:104336. Epub 2019 Jul 2. PMID: 31271846

Article Published Date : Jul 01, 2019

Study Type : Review

Additional Links

Substances : Mangiferin

Diseases : Alzheimer's Disease, Parkinson's Disease

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents

[+]

Mangiferin: A natural bioactive immunomodulating glucosylxanthone with potential against cancer and rheumatoid arthritis.Jun 30, 2024

Click here to read the entire abstract

Pubmed Data : J Biochem Mol Toxicol. 2024 Jul ;38(7):e23765. PMID: 38967724

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Saudi J Biol Sci. 2021 Jan ;28(1):917-927. Epub 2020 Nov 13. PMID: 33424383

Article Published Date : Dec 31, 2020

Study Type : Review

Additional Links

Substances : Mangiferin

Diseases : Memory Disorders

Pharmacological Actions : Neuroprotective Agents

[+]

Renoprotective effects of mangiferin: pharmacological advances and future perspectives.Jan 06, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int Immunopharmacol. 2016 Dec 13 ;43:85-90. Epub 2016 Dec 13. PMID: 27984712

Article Published Date : Dec 12, 2016

Study Type : In Vitro Study

Additional Links

Substances : Mangiferin

Diseases : Lipopolysaccharide-Induced Toxicity, Mastitis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, p300/NF-κB down-regulation

[+]

This review highlights the distribution of mangiferin in plants.Sep 09, 2016

Click here to read the entire abstract

Pubmed Data : Biofactors. 2016 Sep 10 ;42(5):504-514. Epub 2016 Sep 23. PMID: 27658353

Article Published Date : Sep 09, 2016

Study Type : Review

Additional Links

Substances : Mangiferin

Pharmacological Actions : Analgesics, Antioxidants, Chemopreventive, Radioprotective

[+]

This review summarizes the literature pertaining to mangiferin and its associated health claims.May 01, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Lipids Health Dis. 2017 May 2 ;16(1):84. Epub 2017 May 2. PMID: 28464819

Click any topic below to filter + focus research

Mangiferin is a Sub of the following Topic

View the Evidence: 223 Abstracts with Mangiferin Research

Limited to Members Only

Currently Available Sorting Options

Oral administration of mangiferin ameliorates diabetes.Dec 31, 2020

Enhancement of exercise performance by 48 hours, and 15-day supplementation with mangiferin and luteolin in men.Feb 05, 2019

These findings highlight the potential of pre-game mangiferin-quercetin supplementation to enhance intermittent high-intensity efforts in sports such as basketball.Jan 03, 2024

Mangiferin could ameliorate methylmercury mediated mitochondrial dysfunction in human hepatic cells in vitro.Jan 31, 2017

Mangiferin alleviates 6-OHDA-induced Parkinson's disease.Jan 30, 2024

Mangiferin alleviates postpartum depression-like behaviors.Dec 31, 2021

Mangiferin ameliorates obesity-associated inflammation and autophagy in high-fat-diet-fed mice.Dec 04, 2022

Neuroprotective effect of mangiferin against Parkinson's disease.Apr 09, 2023

The protective effect of mangiferin on osteoarthritis.Jan 24, 2022

A significant reduction in blood glucose and HbA1c levels was observed in rats treated with resveratrol or mangiferin.Jul 08, 2018

Anti-allodynic effect of mangiferin in rats with chronic post-ischemia pain.Dec 31, 2017

Anti-angiogenic effects of mangiferin and mechanism of action in metastatic melanoma.Oct 21, 2019

Anti-neoplastic effect of mangiferin on human ovarian adenocarcinoma OVCAR8 cells.Dec 31, 2018

Isolated mangiferin and naringenin exert antidiabetic effects.Jan 24, 2018

Mangifera indica and mangiferin has anti-parasitic and anti-allergic activities.Dec 01, 2003

Mangifera indica exhibits ant-inflammatory properties.Aug 01, 2004

Mangifera indica has immunomodulatory activity in mice. Dec 01, 2001

Mangiferin activates lymphocytes in normal and tumor bearing mice. Nov 01, 1987

Mangiferin activates Nrf2 to attenuate cardiac fibrosis via redistributing glutaminolysis-derived glutamate.Apr 26, 2020

Mangiferin alleviated poststroke cognitive impairment by modulating lipid metabolism in cerebral ischemia/reperfusion.Aug 14, 2024

Mangiferin alleviates arsenic induced oxidative lung injury.Feb 11, 2019

Mangiferin alleviates diabetic pulmonary fibrosis in mice.Apr 30, 2024

Mangiferin alleviates hypertension induced by hyperuricemia.Jun 05, 2018

Mangiferin alleviates ovalbumin-induced allergic rhinitis.May 11, 2020

Mangiferin alleviates renal interstitial fibrosis in streptozotocin-induced diabetic mice.Dec 31, 2019

Mangiferin ameliorated hyperlipidemia by intervening in some major metabolic pathway.Jul 18, 2017

Mangiferin ameliorates acetaminophen-induced hepatotoxicity.Jun 14, 2019

Mangiferin ameliorates cardiac fibrosis in D-galactose-induced aging.Feb 28, 2021

Mangiferin ameliorates fatty liver via modulation of autophagy and inflammation.Oct 08, 2017

Mangiferin ameliorates gestational diabetes mellitus-induced placental oxidative stress, inflammation.Sep 14, 2019

Mangiferin ameliorates hyperuricemic nephropathy which is associated with downregulation of AQP2 and increased urinary uric acid excretion.Dec 31, 2019

Mangiferin ameliorates placental oxidative stress and activates PI3K/Akt/mTOR pathway in mouse model of preeclampsia.Jan 26, 2020

Mangiferin antagonized mitochondrial ROS in NP cells and protected against Intervertebral disc degeneration.Dec 31, 2020

Mangiferin attenuated adverse skeletal muscle changes in obese rats.Dec 31, 2016

Mangiferin attenuated diethynitrosamine-induced hepatocellular carcinoma.Dec 31, 2018

Mangiferin attenuates AOM-induced colorectal cancer in rat's colon by augmentation of apoptotic proteins and antioxidant mechanisms.Jan 07, 2024

Mangiferin attenuates blast-induced traumatic brain injuryApr 24, 2017

Mangiferin attenuates bleomycin-induced pulmonary fibrosis.Mar 06, 2019

Mangiferin attenuates cisplatin-induced acute kidney injury.Aug 05, 2018

Mangiferin can alleviate chronic unpredictable mild stress induced tumor growth and the treatment of colorectal liver metastases patients.Feb 28, 2023

Mangiferin could increase urinary iron excretion and to decrease iron accumulation in liver and heart.Sep 05, 2018

Mangiferin could provide a new target for the therapy and prevention of skin inflammation.Feb 17, 2017

Mangiferin enhances endochondral ossification-based bone repair in massive bone defect.Mar 15, 2018

Mangiferin exert cardioprotective and anti-apoptotic effects in heart failure.May 14, 2020

Mangiferin exert protective effects on joints of adjuvant-induced arthritis.Nov 30, 2021

Mangiferin exerts neuroprotective effects against focal cerebral ischemia.Nov 01, 2022

Mangiferin exhibits anti-diabetic properties.Mar 01, 2001

Mangiferin has a protective role on arsenic induced hepatotoxicity.Mar 27, 2016

Mangiferin has anti-inflammatory and analgesic properties when locally administrated.Jul 04, 2018

Mangiferin has anti-inflammatory effects on periodontitis.Jan 29, 2016

Mangiferin improved palmitate-induced-insulin resistance.Dec 31, 2018

Mangiferin improves hepatic damage-associated molecular patterns, lipid metabolic disorder and mitochondrial dysfunction in alcohol hepatitis.May 29, 2019

Mangiferin improves hepatic lipid metabolism.Dec 31, 2017

Mangiferin induces immune responses and evaluates the survival rate in WEHI-3 cell generated mouse leukemia in vivo.Sep 04, 2020

Mangiferin induces islet regeneration in aged mice.Feb 28, 2018

Mangiferin inhibits apoptosis and oxidative stress caused by dexamethasone.Apr 30, 2018

Mangiferin inhibits bowel carcinogenesis in male rats.Feb 26, 2001

Mangiferin inhibits high-fat diet induced vascular injury via regulation of PTEN/AKT/eNOS pathway.Jun 30, 2018

Mangiferin inhibits hippocampal NLRP3 inflammasome and exerts antidepressant effects.Apr 12, 2017

Mangiferin inhibits passive cutaneous anaphylaxis reaction and pruritus in mice.Oct 01, 2009

Mangiferin is a new potential antimalarial and anticancer treatment for targeting serine hydroxymethyltransferase.Aug 31, 2023

Mangiferin is neuroprotective against early brain injury after subarachnoid hemorrhage.Sep 18, 2017

Mangiferin is potent anti-inflammatory compound that reduces inflammation.Feb 19, 2017

Mangiferin may ameliorate colitis by the restoration of disturbed Th17/Treg cells and inhibition of macrophage activation.Apr 30, 2016

Mangiferin may be considered a potential antineoplastic drug for the future treatment of cancer.Mar 31, 2016

Mangiferin may be of value in the prevention of benzo(a)pyrene-induced lung carcinogenesis.Sep 01, 2003

Mangiferin may reduce toxicity associated with hyperglycemia and atherogenicity in diabetic rats.May 01, 2001

Mangiferin might be a potential effective agent for the management of alcoholic liver injury.Sep 23, 2020

Mangiferin mitigates di-(2-ethylhexyl) phthalate-induced testicular injury.Oct 29, 2021

Mangiferin mitigates lipopolysaccharide-induced lung injury.Dec 31, 2020

Mangiferin plays a protective role in moderation of sepsis-induced lung injury.Feb 11, 2018

Mangiferin potentiates neuroprotection by isoflurane in neonatal hypoxic brain injury.Oct 18, 2018

Mangiferin

View the Evidence:
223 Abstracts with Mangiferin Research