Medicinal Mushrooms

Name	AC	CK
Cancers: All	53	169
Inflammation	72	148
Breast Cancer	63	130
Oxidative Stress	63	121
Diabetes Mellitus: Type 2	45	110
Liver Cancer	34	71
Alzheimer's Disease	33	69
Lung Cancer	38	66
Obesity	24	61
Prostate Cancer	20	50
Lipopolysaccharide-Induced Toxicity	35	48
Colon Cancer	28	47
Depression	21	46
High Fat Diet	21	42
Hyperlipidemia	20	41
Cognitive Decline/Dysfunction	13	39
Colorectal Cancer	21	39
Breast Cancer: Triple Negative	21	37
Insulin Resistance	10	37
Aging	21	36
Colitis	17	35
Aging Skin	3	32
Cervical Cancer	15	31
Chemically-Induced Liver Damage	17	31
Gastric Cancer	23	31
Atherosclerosis	12	30
Diabetes Mellitus: Type 1	9	30
Fatigue	7	30
Wrinkles	2	30
Cancer Metastasis	12	29
Hydrogen Peroxide Induced Toxicity	15	29
Diabetic Nephropathy	15	28
Neurodegenerative Diseases	18	28
Alcohol Toxicity	14	26
Parkinson's Disease	14	26
Sleep Disorders	5	26
Hepatitis B	5	24
Hyperglycemia	16	24
Asthma	7	21
Brain Inflammation	13	21
Alcoholic Liver Disease	11	20
Bladder Cancer	9	20
Chemotherapy-Induced Toxicity: Cyclophosphamide	8	20
Herpes Zoster	2	20
Osteopenia	1	20
Shingles	2	20
Chemotherapy-Induced Toxicity	6	19
Chemotherapy-Induced Toxicity: Cisplatin	11	19
Coronavirus Infection	11	19
DNA damage	8	19
Dementia	6	19
Melanoma	12	19
Chemotherapy-Induced Toxicity: Doxorubicin	10	18
Radiation Induced Illness	4	18
Lipid Peroxidation	7	17
Gastric Ulcer	9	16
Hypercholesterolemia	8	16
Inflammatory Bowel Diseases	8	15
Nonalcoholic fatty liver disease (NAFLD)	8	15
Anxiety	8	14
Carcinoma: Non-Small-Cell Lung	12	14
Diabetic Complications	7	14
Glioma	8	14
Ovarian Cancer	5	14
Pancreatic Cancer	5	14
Polycystic Ovary Syndrome	3	14
Ulcerative Colitis	7	14
Chemotherapy	3	13
Dyslipidemias	7	13
Kidney Fibrosis	8	13
Leukemia	12	13
Liver Damage	6	13
Endothelial Dysfunction	2	12
Influenza	8	12
Memory Disorders	6	12
Prediabetes	2	12
Sepsis	6	12
Stress	2	12
Anxiety Disorders	2	11
Arthritis	5	11
Diabetes: Cardiovascular Illness	2	11
Endometrial Cancer	2	11
HIV Infections	11	11
High Cholesterol	6	11
Kidney Damage	6	11
Osteoporosis	4	11
Prostatic Hyperplasia: Benign	2	11
Tumors	6	11
Upper Respiratory Infections	2	11
Breast Cancer: Prevention	1	10
C-Reactive Protein	1	10
COPD	1	10
Cadmium Poisoning	5	10
Cold Sore	1	10
Dengue	4	10
Depressive Disorder	1	10
Dry Eye Syndromes	1	10
Focal segmental glomerulosclerosis (FSGS)	1	10
HSV-2	1	10
Herpes Genitalis	1	10
Kidney Cancer	6	10
Kidney Diseases	1	10
Kidney Failure	1	10
Lupus Nephritis	1	10
Lymphoma	7	10
Macular Degeneration	1	10
Myelodysplastic Syndromes	1	10
Organ Transplantation: Kidney	1	10
Overweight	1	10
Post-Herpetic Neuralgia	1	10
Pseudomonas aeruginosa	9	10
Quality of Life: Poor	1	10
Taste Disorders	1	10
Toxoplasma gondii Infection	6	10
Ultraviolet Radiation Induced Damage	7	10
Weight Probems: Appetite	1	10
Allergies	4	9
Immune Disorders: Low Immune Function	5	9
Influenza A	6	9
Klebsiella Infections	5	9
Liver Damage: Drug-Induced	4	9
Cerebral Ischemia	4	8
Hepatitis C	6	8
Hypertension	4	8
Immune Dysregulation: TH1/TH2 imbalance	5	8
Liver Cirrhosis	4	8
Liver Fibrosis	5	8
Lung Damage	4	8
Rheumatoid Arthritis	5	8
Acetaminophen (Tylenol) Toxicity	4	7
Cardiovascular Diseases	5	7
Chemotherapy-Induced Kidney Damage	4	7
Chronic Kidney Disease (CKD)	4	7
Dysbiosis	3	7
Epilepsy	5	7
Lead Poisoning	3	7
Wound Healing	4	7
Aging: Brain	3	6
Brain Ischemia	3	6
Brain: Oxidative Stress	5	6
Breast Cancer: Metastatic	3	6
Chemotherapy and Radiation Toxicity	3	6
Chemotherapy-Induced Toxicity: 5-fluorouracil	3	6
Chemotherapy-Induced Toxicity: Bleomycin	3	6
Diabetes: Oxidative Stress	4	6
Escherichia coli Infections	5	6
Fatty Liver	3	6
Hepatic Steatosis	4	6
Hyperuricemia	3	6
Liver Injury: Ischemia/reperfusion	3	6
Myelotoxicity	3	6
Myocardial Ischemia	3	6
Pancreatitis	3	6
Pulmonary Fibrosis: Bleomycin-Induced	3	6
Staphylococcus aureus infection	6	6
Atopic Dermatitis	3	5
Cholangiocarcinoma	1	5
Coronavirus Disease (Covid-19)	3	5
Crohn's Disease	1	5
Esophageal Cancer	3	5
Glioblastoma	2	5
H1N1 Infection	3	5
Hypoglycemia	3	5
Multiple Myeloma	4	5
Osteosarcoma	5	5
Skin Cancer	3	5
Staphylococcus epidermidis	4	5
Triglycerides: Elevated	3	5
Acute Myeloid Leukemia	3	4
Aluminum Toxicity	2	4
Arteriosclerosis	2	4
Cancers: Multi-Drug Resistant	3	4
Candida Albicans	3	4
Chemotherapy Induced Myelotoxicity	2	4
Diarrhea: Antibiotic-Associated	2	4
Endometritis	2	4
Epstein-Barr Virus Infections	3	4
Food Allergies	2	4
Gastrointestinal Diseases	3	4
Gastrointestinal Inflammation	2	4
Hair Loss	2	4
Herpes Simplex Virus Type 1	4	4
High Cholesterol: very low density lipoprotein (VLDL)	2	4
Hypoxia	3	4
Infertility: Male	2	4
Ischemia	3	4
Kidney Failure: Chronic	2	4
Liver Disease	2	4
Low Immune Function: Natural Killer Cells	2	4
Muscle Atrophy	2	4
Periodontitis	2	4
Peripheral Nerve Diseases	2	4
Pneumonia	2	4
Polycystic Kidney Diseases	2	4
Promyelocytic leukemia	3	4
Acute lymphoblastic leukemia (ALL)	1	3
Bacillus subtilis infections	2	3
Cancers: Drug Resistant	3	3
Cardiomyopathy	2	3
Cataract	2	3
Coronary Artery Disease	2	3
Ehrlich carcinoma	2	3
Fungal Infection	2	3
Gram-Negative Bacterial Infections	3	3
Gram-Positive Bacterial Infections	3	3
Helicobacter Pylori Infection	2	3
Herpes Simplex Virus Type 2	2	3
Infant Acute Monocytic Leukemia	2	3
Irritable Bowel Syndrome	2	3
Laryngeal Cancer	1	3
Lung Injury: Acute	2	3
Malaria	2	3
Myocardial Infarction	2	3
Neutropenia: Chemotherapy Induced	3	3
Oral Cancer	3	3
Organ Transplantation	2	3
Rhinovirus Infection	2	3
Sarcoidosis	1	3
Schistosomiasis	2	3
Acrylamide-induced toxicity	1	2
Acute Respiratory Distress Syndrome	1	2
Advanced Glycation End products (AGE)	2	2
Aflatoxicosis	1	2
Amyloid toxicity	1	2
Amyloid β peptide toxicity	1	2
Anaphylactic Reaction	1	2
Androgen-Induced Diseases	2	2
Androgenic Alopecia	1	2
Animal Cancers	1	2
Arrhythmias: Cardiac	1	2
Asthma: Bronchial	1	2
Ataxia: Cerebellar	1	2
Athletic Performance	1	2
Autoimmune Diseases	1	2
Bacterial Prostatitis	1	2
Brain Injury: Traumatic	1	2
Brain: Microglial Activation	1	2
Breast Cancer: Chemically-Induced	1	2
Breast Cancer: Drug Resistant	2	2
Breast Cancer: Inflammatory	1	2
Bronchitis	1	2
Cachexia	1	2
Candidiasis	1	2
Cardiac Hypertrophy	1	2
Cardiomegaly	1	2
Cat Diseases	1	2
Cerebral Hypoperfusion	1	2
Chemotherapy-Induced Toxicity: Mitomycin-C	1	2
Chemotherapy-Induced Toxicity: Paclitaxel	1	2
Chronic Myeloid Leukemia	2	2
Chronic Obstructive Pulmonary Disease	1	2
Chronic Pain	1	2
Citrobacter Infection	1	2
Colon Cancer: Prevention	1	2
Coxsackievirus Infections	1	2
Cysts	1	2
Depression	1	2
Dermatitis: Contact	1	2
Diabetic Neuropathy	1	2
Duodenal Ulcer	1	2
Dyspepsia	1	2
Dysthymic Disorder	1	2
End Stage Renal Disease	1	2
Enterobacteriaceae Infections	1	2
Enterococcus Infections	1	2
Enterovirus 71	2	2
Erectile Dysfunction	1	2
Fatigue: Excercise-Induced	1	2
Female	1	2
Fibrosis	1	2
Formaldehyde Toxicity	1	2
Gastric Ulcers	1	2
Gastrointestinal Complaints	1	2
Gestational Diabetes	1	2
H3N2 Infection	1	2
H5N1 Infection	1	2
HSV-1	1	2
Heart Failure	1	2
Hemorrhagic Shock	1	2
Hepatoma	2	2
High Sugar Diet	1	2
Histamine: Elevated	1	2
Human Flu	1	2
Human Influenza	1	2
Hyperinsulinism	1	2
Hypertension: Portal	1	2
Hypertension: Pulmonary	1	2
Insomnia	1	2
Ischemia: Myocardial	1	2
Kidney Damage: Chemically-Induced	1	2
Kidney Damage: Drug-Induced	1	2
Learning disorders	1	2
Leukemia: Monocytic	2	2
Lipid Metabolism: Abnormalities	1	2
Listeria Infections	1	2
Liver Cancer: Prevention	1	2
Liver Steatosis	1	2
Low Immune Function: Splenic Dysfunction	1	2
Low Immune Function: Thymus Dysfunction	1	2
Low Libido	1	2
Lupus Erythematosus: Systemic	1	2
Lyme Disease	1	2
Mental Fatigue	1	2
Metabolic Diseases	2	2
Metabolic Syndrome X	1	2
Multi-Organ Failure	1	2
Mycobacterium Tuberculosis	1	2
Neurologic Disorders	2	2
Neuropathic Pain	1	2
Neutropenia	2	2
Neutropenia: Cyclic	2	2
Optic Neuropathy	1	2
Organ Transplantation: Skin	1	2
Osteoarthritis	1	2
Osteoarthritis: Knee	1	2
Ovarian Failure	1	2
Pancreatitis: Chronic	1	2
Parasitic Diseases	2	2
Progesterone: Low	1	2
Prostatitis: Chronic	1	2
Pulmonary Cancer	1	2
Pulmonary Fibrosis	1	2
Radiation	1	2
Radiation Induced Illness: Enteritis	1	2
Respiratory Infections	1	2
Salmonella Infections	2	2
Sciatic Nerve Crush Injury	1	2
Sexual Arousal Disorder	1	2
Sexual Dysfunction	1	2
Squamous cell carcinoma	2	2
Staphylococcus aureus: Methicillin-resistant (MRSA)	2	2
Stomach Cancer	2	2
Streptococcus Infections	1	2
Streptococcus infections: Group A	1	2
Stroke: Attenuation/Recovery	1	2
Swine Flu Associated Virus	1	2
Systemic Lupus Erythematosus	1	2
Testicular Cancer	1	2
Testicular Injury: Cadmium-Induced	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Thrombosis	2	2
Thymic Dysplasia	1	2
Thyroiditis: Autoimmune	1	2
Toxoplasmosis	1	2
Traumatic Brain Injury	1	2
Urolithiasis	1	2
Water Retention	1	2
West Nile Fever	1	2
Adenoviridae Infections	1	1
Adrenal Gland Diseases	1	1
Adrenal Gland: Enhanced Apoptosis	1	1
Arthritis: Rheumatoid	2	1
Aspergillosis	1	1
Avian Influenza	1	1
Bacterial Infections	1	1
Bacterial Infections and Mycoses	1	1
Bisphenol Toxicity	1	1
Brain Cancer	1	1
Brain Hypoxia	1	1
Breast Cancer: Lung Metastasis	1	1
Cancers: Canine	1	1
Carcinoma: Small Cell Lung	1	1
Central Nervous System Diseases	1	1
Chronic Lymphocytic Leukemia	1	1
Clotting	1	1
Cryptococcosis	1	1
Cystic Fibrosis	1	1
Degenerative Disk Disease	1	1
Demyelinating Diseases	1	1
Dry Skin	1	1
Endotoxemia	1	1
Epithelial Neoplasms: Malignant	1	1
Gallbladder Cancer	1	1
Hepatoma: Multidrug Resistant	1	1
Influenza B	1	1
Larynx Neoplasms	1	1
Leukemia: Acute myelogenous leukemia (AML)	1	1
Leukemia: Acute promyelocytic leukemia	1	1
Leukemia: T-cell prolymphocytic leukemia (T-PLL)	1	1
Leukopenia: Chemotherapy Induced	1	1
Malignant Melanoma	1	1
Melanoma: Metastatic	1	1
Micrococcus luteus infections	1	1
Mycotoxin Toxicity	1	1
Nasopharyngeal Cancer	1	1
Neurological Conditions	1	1
Neurological Disorders	1	1
Neutropenia: Severe Congenital	1	1
Pancreatic Fibrosis	1	1
Phthalate Toxicity	1	1
Pigmentation Disorders	1	1
Pulmonary Hypertension	1	1
Radiation Disaster Associated Toxicity	1	1
Retinoblastoma	1	1
Sarcoma	1	1
Stroke	1	1
Testosterone-Induced	1	1
Testosterone: Too Low	1	1
Tongue Cancer	1	1
Tuberculosis	1	1
Vitamin B 12 Deficiency	1	1
Vitamin D Deficiency	1	1

Name	AC	CK
Anti-Inflammatory Agents	238	461
Antioxidants	222	431
Immunomodulatory	109	257
Antiproliferative	152	248
Apoptotic	144	208
Neuroprotective Agents	102	194
Tumor Necrosis Factor (TNF) Alpha Inhibitor	84	168
Hepatoprotective	74	153
Hypoglycemic Agents	55	118
Chemotherapeutic	30	117
Gastrointestinal Agents	51	116
Interleukin-6 Downregulation	58	113
NF-kappaB Inhibitor	65	111
Interleukin-1 beta downregulation	56	110
Hypolipidemic	50	98
Anti-Apoptotic	51	90
Antineoplastic Agents	42	73
Renoprotective	39	70
Chemopreventive	28	69
Cell cycle arrest	45	67
Chemoprotective Agents	28	67
Immunostimulatory	22	63
Anti-metastatic	38	61
Antidepressive Agents	22	57
Antiviral Agents	41	56
Cyclooxygenase 2 Inhibitors	30	50
Cardioprotective	26	42
Malondialdehyde Down-regulation	19	34
Anti-Fibrotic	20	33
Anti-Bacterial Agents	26	32
Nrf2 activation	19	31
Osteoprotective	5	31
Gastroprotective	17	30
Antifungal Agents	7	27
Superoxide Dismutase Up-regulation	15	27
Anti-Anxiety Agents	9	24
Interleukin-10 upregulation	8	24
Photoprotective	6	22
Autophagy Up-regulation	12	21
Bcl-2 protein down-regulation	12	20
Cytotoxic	15	19
Brain-derived neurotrophic factor modulator	5	18
Chemosensitizer	13	18
Analgesics	5	17
Heme oxygenase-1 up-regulation	9	15
Nitric Oxide Inhibitor	7	15
Alpha-glucosidase inhibitor	12	14
Anticarcinogenic Agents	7	14
Anticholesteremic Agents	8	14
Matrix metalloproteinase-9 (MMP-9) inhibitor	9	13
MicroRNA modulator	9	13
Neuritogenic	9	13
Antihypertensive Agents	8	12
Interferon-gamma (IFN-gamma) inducer	2	12
Radioprotective	6	12
Anti-Ulcer Agents	6	11
Tumor Suppressor Protein p53 Upregulation	11	11
Antiparasitic Agents	7	10
Anxiolytic	1	10
Appetite Depressants	1	10
Interleukin-4 upregulation	1	10
Cyclin D1 Down-Regulation	4	9
Genoprotective	4	9
Prophylactic Agents	5	9
Angiogenesis Inhibitors	6	8
Insulin Sensitizers	4	8
P21 Activation	4	8
Pancreato Protective Agents	6	8
Anti-Allergic Agents	3	7
Anti-Tumor	4	7
Antimutagenic Agents	3	7
Caspase-3 Activation	4	7
Interleukin-8 downregulation	5	7
Anti-Asthmatic Agents	3	6
Anti-atherogenic	3	6
Interleukin-12 upregulation	4	6
Interleukin-4 downregulation	3	6
Neurogenesis	4	6
Osteogenic	1	6
Radiosensitizer	4	6
Uricosuric Agents	3	6
Anti-Angiogenic	4	5
Anti-HIV Agents	5	5
Antinoceceptive	3	5
Caspase-9 Activation	3	5
Detoxifier	2	5
Interferon Gamma Reducer	3	5
Interleukin-18 down-regulation	3	5
Transforming growth factor beta (TGF-β) inhibitor	3	5
Alpha-amylase inhibitor	4	4
Antimicrobial	4	4
Aromatase Inhibitors	3	4
Catalase Up-Regulation	2	4
Enzyme Inhibitors	2	4
Glutathione Upregulation	2	4
Interleukin-2 Downregulation	2	4
Matrix metalloproteinase-2 (MMP-2) inhibitor	4	4
Radiation-Protective Agents	2	4
Transforming growth factor beta (TGF-β) upregulation	2	4
Anticonvulsants	2	3
Hypnotics and Sedatives	2	3
Immunomodulatory: Th17 downregulation	2	3
Immunosuppressive Agents	2	3
Matrix metalloproteinase-1 (MMP-1) inhibitor	2	3
Neurominidase Inhibitor	2	3
Tumor Necrosis Factor (TNF) Alpha Enhancer	2	3
Vascular Endothelial Growth Factor Inhibitors	2	3
Wnt/β-catenin signaling pathway modulation	3	3
5-Lipoxygenase Inhibitor	1	2
5-alpha reductase inhibitor	2	2
Acetylcholinesterase Inhibitor	2	2
Anti-Glycation Agents	2	2
Antioxidant Effects	1	2
Aphrodisiac	1	2
Bax/Bcl2 ratio: Increase	1	2
Bcl-xL down-regulation	1	2
Caspase-8 activation	1	2
Chelating Agents	1	2
Cytoprotective	1	2
DNA Repair Up-regulation	1	2
Diuretics	1	2
Heat Shock Protein Down-Regulation	1	2
Hematopoietic	2	2
Interleukin-1 alpha downregulation	1	2
Interleukin-1 beta upregulation	1	2
Interleukin-5 downregulation	1	2
Interleukin-6 upregulation	1	2
Lactate Dehydrogenase A Inhibitor	1	2
Nitric Oxide Enhancer	2	2
Platelet Aggregation Inhibitors	2	2
Postaglandin PGE2 downregulation	2	2
Protein tyrosine phosphatase 1B (PTP1B) modulator	1	2
Regenerative	1	2
SIRT1 Activator	1	2
Secretagogue	1	2
Telomerase Inhibitor	2	2
Topoisomerase I inhibitor	1	2
Topoisomerase II Inhibitor	1	2
interleukin-13 down-regulation	1	2
Angiogenesis Inducing Agents	1	1
Angiotensin-Converting Enzyme Inhibitors	1	1
Anti-Infective Agents	1	1
Anti-Platelet	1	1
Anti-bacterial	1	1
Anticholinergic	1	1
Antimalarials	1	1
Antimycobacterial	1	1
Autophagy Inhibitors	1	1
Chondroprotective	1	1
Cyclooxygenase Inhibitors	1	1
Estrogen Receptor Modulators	1	1
Gene Protective	1	1
HIV Protease Inhibitors	1	1
Heat Shock Protein Inducer	1	1
Interferon Inducers	1	1
Interleukin-10 downregulation	1	1
Interleukin-18 upregulation	1	1
Matrix Metalloproteinase-7 (MMP-7) Inhibitor	1	1
Monoamine Oxidase Inhibitors	1	1
Multidrug Resistance Gene Modulators	1	1
Platelet aggregation inhibitor: collagen-induced aggregation	1	1
Prostaglandin PGE2 downregulation	1	1
Quorum Sensing Inhibition	1	1
Reactive Oxygen Species (ROS) attenuation	1	1
Reverse Transcriptase Inhibitors	1	1
STAT3 Inhibitor	1	1
Tyrosinase inhibitors	1	1
Vascular Cell Adhesion Molecule-1 Inhibitor	1	1
Vascular Endothelial Growth Factor A Inhibitor	1	1
Vasoprotective	1	1
Wnt/β-catenin pathway down-regulation	1	1

Click here to read the entire abstract

Pubmed Data : Arch Dermatol Res. 2016 Apr ;308(3):183-92. Epub 2016 Feb 25. PMID: 26914455

Article Published Date : Mar 31, 2016

Study Type : Human In Vitro, Human Study

Additional Links

Substances : Mushrooms: All

Diseases : Aging Skin, Wrinkles

Pharmacological Actions : Photoprotective

[+]

NAD-driven sirtuin activation by Cordyceps sinensis extract: exploring the adaptogenic aotential to promote skin longevity.Apr 11, 2024

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2024 Apr 12 ;25(8). Epub 2024 Apr 12. PMID: 38673866

Pubmed Data : Am J Chin Med. 2005;33(4):517-23. PMID: 16173526

Article Published Date : Jan 01, 2005

Study Type : Human Study

Additional Links

Substances : Reishi Mushroom

Diseases : Herpes Zoster, Shingles

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A phase I/II trial of a polysaccharide extract from Maitake mushroom in breast cancer patients.Aug 31, 2009

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Pubmed Data : J Cancer Res Clin Oncol. 2009 Sep ;135(9):1215-21. Epub 2009 Mar 1. PMID: 19253021

Article Published Date : Aug 31, 2009

Study Type : Human Study

Additional Links

Substances : Maitake Mushroom

Diseases : Breast Cancer

Pharmacological Actions : Immunomodulatory, Immunostimulatory

Additional Keywords : Polysaccharides

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Agaricus blazei extract in combination with metformin and gliclazide improve insulin resistance in type 2 diabetics. Dec 01, 1999

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Pubmed Data : J Surg Oncol. 1999 Dec;72(4):230-9. PMID: 17309383

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Foods. 2021 Jul 5 ;10(7). Epub 2021 Jul 5. PMID: 34359426

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Indian Heart J. 2018 Sep - Oct;70(5):608-614. Epub 2017 Dec 14. PMID: 30392496

Effects of Macuprev® supplementation in age-related macular degeneration.Aug 31, 2019

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Pubmed Data : Adv Ther. 2019 Sep ;36(9):2493-2505. Epub 2019 Jun 25. PMID: 31243641

Article Published Date : Aug 31, 2019

Study Type : Human Study

Additional Links

Substances : Reishi Mushroom

Diseases : Macular Degeneration

Pharmacological Actions : Antioxidants

[+]

Additional Keywords : Risk Reduction

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Hericium erinaceus improves mood and sleep disorders in patients affected by overweight or obesity.Dec 31, 2018

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Pubmed Data : J Altern Complement Med. 2010 Dec ;16(12):1295-9. Epub 2010 Oct 29. PMID: 21034160

Article Published Date : Nov 30, 2010

Study Type : Human Study

Additional Links

Substances : Maitake Mushroom

Diseases : Insulin Resistance, Polycystic Ovary Syndrome

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Mushroom mycelium extract was an ineffective treatment for reducing 50% or more the patient prostate specific antigen values.Sep 30, 2010

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Pubmed Data : Pharmacol Res. 2022 Jan ;175:105979. Epub 2021 Nov 16. PMID: 34798266

Article Published Date : Dec 31, 2021

Study Type : Human Study

Additional Links

Substances : King trumpet mushroom

Diseases : Obesity

Pharmacological Actions : Appetite Depressants

[+]

Prevention of early Alzheimer's disease by Erinacine A-enriched Hericium erinaceus mycelia.Dec 31, 2019

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Pubmed Data : Front Aging Neurosci. 2020 ;12:155. Epub 2020 Jun 3. PMID: 32581767

Article Published Date : Dec 31, 2019

Study Type : Human Study

Additional Links

Substances : Lion's Mane (Hericium Erinaceus)

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

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Regular shiitake mushroom consumption resulted in improved immunity.Dec 31, 2014

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Pubmed Data : J Am Coll Nutr. 2015 ;34(6):478-87. Epub 2015 Apr 11. PMID: 25866155

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Pubmed Data : Psychiatry Res. 2015 Jul 15. Epub 2015 Jul 15. PMID: 26208984

Article Published Date : Jul 14, 2015

Study Type : Human Study

Additional Links

Substances : Fruit: All, Green Tea, Mushrooms: All , Potatoes, Seaweed, Vegetables: All

Diseases : Depressive Disorder

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Risk Reduction

[+]

The acute and chronic effects of Lion's mane mushroom supplementation on cognitive function, stress and mood in young adults.Nov 19, 2023

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Pubmed Data : Int J Med Mushrooms. 2018 ;20(8):705-716. PMID: 30317947

Article Published Date : Dec 31, 2017

Study Type : Human Study

Additional Links

Substances : Beta-glucan, Reishi Mushroom, Yoghurt

Pharmacological Actions : Immunomodulatory

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Triterpene ganoderic acid inhibited production of TNF-α and other proinflammatory cytokines by PBMCs and inflamed CD colonic mucosa due to blockage of NF-κB activation.May 18, 2015

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Pubmed Data : Inflamm Bowel Dis. 2015 May 19. Epub 2015 May 19. PMID: 25993687

Article Published Date : May 18, 2015

Study Type : Human In Vitro

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Substances : Reishi Mushroom

Diseases : Crohn's Disease

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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verticillin A from Verticillium-infected wild mushrooms as a potent anti-cancer agent that effectively suppresses 5-FU-resistant human colon cancer cells. Aug 31, 2015

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Pubmed Data : Exp Gerontol. 2023 May ;175:112147. Epub 2023 Mar 28. PMID: 36925084

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Pubmed Data : Int J Med Mushrooms. 2015 ;17(11):1055-60. PMID: 26853960

Article Published Date : Dec 31, 2014

Study Type : Animal Study

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Substances : Lion's Mane (Hericium Erinaceus)

Diseases : Gastric Ulcer

Pharmacological Actions : Anti-Ulcer Agents

Additional Keywords : Plant Extracts

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A polysaccharide from Inonotus obliquus ameliorates intestinal barrier dysfunction in mice with type 2 diabetes mellitus.Jun 13, 2022

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Pubmed Data : Int J Biol Macromol. 2022 Jun 14. Epub 2022 Jun 14. PMID: 35714869

Article Published Date : Jun 13, 2022

Study Type : Animal Study

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Substances : Chaga Mushroom (Inonotus obliquus)

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Gastroprotective

Additional Keywords : Polysaccharides

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A polysaccharide from Pleurotus nebrodensis might be a promising candidate for preventing hepatic I/R injury.Nov 30, 2017

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Pubmed Data : Int J Biol Macromol. 2017 Dec ;105(Pt 1):447-451. Epub 2017 Jul 11. PMID: 28709897

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Pubmed Data : Oncol Rep. 2006 Dec;16(6):1181-7. PMID: 17089035

Article Published Date : Dec 01, 2006

Study Type : Animal Study

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Substances : Reishi Mushroom

Diseases : Lung Cancer, Pulmonary Cancer

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A water-soluble polysaccharide from chaga mushroom had potential as a natural antitumor agent with immunomodulatory activity.Sep 30, 2012

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Pubmed Data : Carbohydr Polym. 2012 Oct 1 ;90(2):870-4. Epub 2012 Jun 17. PMID: 22840014

Article Published Date : Sep 30, 2012

Study Type : Animal Study

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Substances : Chaga Mushroom (Inonotus obliquus)

Diseases : Gastric Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Immunomodulatory

Additional Keywords : Plant Extracts

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A white button mushroom extract acted as a potent dietary antioxidant and protects against Al-mediated neurotoxicity, by abrogating neuronal oxidative stress.Aug 31, 2014

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Pubmed Data : Pak J Biol Sci. 2014 Sep ;17(9):1079-82. PMID: 26031030

Article Published Date : Aug 31, 2014

Pubmed Data : J Exp Ther Oncol. 2009;8(1):43-51. PMID: 19827270

Article Published Date : Jan 01, 2009

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Pubmed Data : Life Sci. 2006 May 30 ;79(1):72-80. Epub 2006 Feb 3. PMID: 16458328

Article Published Date : May 29, 2006

Study Type : Animal Study

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Substances : Chaga Mushroom (Inonotus obliquus)

Diseases : Melanoma

Pharmacological Actions : Immunostimulatory

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Bachu mushroom polysaccharide alleviates colonic injury by modulating the gut microbiota.Dec 31, 2021

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Pubmed Data : Comput Math Methods Med. 2022 ;2022:1353724. Epub 2022 Mar 14. PMID: 35371288

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Pubmed Data : BMC Complement Altern Med. 2016 Dec 3 ;16(1):500. Epub 2016 Dec 3. PMID: 27912745

Article Published Date : Dec 02, 2016

Study Type : Animal Study

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Substances : Reishi Mushroom

Diseases : High Fat Diet, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents

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Pubmed Data : Molecules. 2014 ;19(9):14383-95. Epub 2014 Sep 12. PMID: 25221864

Article Published Date : Dec 31, 2013

Study Type : Animal Study, In Vitro Study

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Substances : Antrodia camphorata, Chaga Mushroom (Inonotus obliquus), Phellinus Linteus, Reishi Mushroom

Diseases : Melanoma

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Chemopreventive, Cyclin D1 Down-Regulation, P21 Activation

Additional Keywords : Plant Extracts, Superiority of Natural Substances versus Drugs

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Chaga mushroom and its compounds could be used as natural anticancer ingredients.May 31, 2010

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Pubmed Data : Nutr Res Pract. 2010 Jun ;4(3):177-82. Epub 2010 Jun 29. PMID: 20607061

Article Published Date : May 31, 2010

Study Type : Animal Study, In Vitro Study

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Substances : Chaga Mushroom (Inonotus obliquus)

Diseases : Breast Cancer, Carcinoma: Non-Small-Cell Lung, Cervical Cancer, Gastric Cancer

Pharmacological Actions : Antiproliferative

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Chaga mushroom extract significantly reduced the total IgE levels in mice and slightly affected the production of IgG1.Mar 31, 2013

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Pubmed Data : Int Immunopharmacol. 2013 Apr ;15(4):666-70. Epub 2013 Mar 25. PMID: 23535020

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Continuous intake of the I. obliquus extract could suppress tumor progression.Apr 30, 2016

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Pubmed Data : Heliyon. 2016 May ;2(5):e00111. Epub 2016 May 12. PMID: 27441282

Article Published Date : Apr 30, 2016

Study Type : Animal Study, In Vitro Study

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Substances : Chaga Mushroom (Inonotus obliquus)

Diseases : Lung Cancer

Pharmacological Actions : Antiproliferative , Chemopreventive

[+]

Cordycepin mitigates MPTP-induced Parkinson's disease through inhibiting TLR/NF-κB signaling pathway.Feb 17, 2019

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Pubmed Data : Life Sci. 2019 Feb 18. Epub 2019 Feb 18. PMID: 30790609

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Pubmed Data : Front Pharmacol. 2021 ;12:801094. Epub 2022 Feb 10. PMID: 35222012

Article Published Date : Dec 31, 2020

Study Type : Animal Study

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Substances : Medicinal Mushrooms

Diseases : Hypertension, Kidney Damage, Kidney Fibrosis

Pharmacological Actions : Anti-Fibrotic, Renoprotective

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Cordyceps cicadae extracts ameliorate renal malfunction in a remnant kidney model.Nov 30, 2011

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Pubmed Data : J Zhejiang Univ Sci B. 2011 Dec ;12(12):1024-33. PMID: 22135152

Article Published Date : Nov 30, 2011

Study Type : Animal Study

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Substances : Medicinal Mushrooms

Diseases : Kidney Failure: Chronic, Kidney Fibrosis

Pharmacological Actions : Anti-Fibrotic, Renoprotective

Additional Keywords : Plant Extracts

[+]

Cordyceps cicadae mycelia ameliorate cisplatin-induced acute kidney injury.Dec 31, 2019

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Pubmed Data : Oxid Med Cell Longev. 2020 ;2020:7912763. Epub 2020 Feb 6. PMID: 32089779

Article Published Date : Dec 31, 2019

Study Type : Animal Study

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Substances : Medicinal Mushrooms

Diseases : Chemotherapy-Induced Kidney Damage, Chemotherapy-Induced Toxicity: Cisplatin

Pharmacological Actions : Antioxidants, Chemoprotective Agents, Heme oxygenase-1 up-regulation, Nrf2 activation, Renoprotective

[+]

Cordyceps cicadae NTTU 868 mycelia fermented with deep ocean water minerals prevents D-galactose-induced memory deficits.Apr 18, 2023

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Pubmed Data : Nutrients. 2023 Apr 19 ;15(8). Epub 2023 Apr 19. PMID: 37111188

Article Published Date : Apr 18, 2023

Study Type : Animal Study

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Substances : Fermented Foods an

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View the Evidence: 1236 Abstracts with Medicinal Mushrooms Research

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Benefits of herbal formulae containing Poria cocos for type 2 diabetes mellitus.Dec 31, 2021

Antitumor activities of Grifola frondosa polysaccharide.Jul 12, 2021

C. versicolor and G. lucidum related natural products might have potential benefits on the overall survival and quality of life in cancer patients.Dec 31, 2018

Meta-analysis on effect of Grifola frondosa polysaccharide in regulating in vivo immunoregulatory function.Nov 30, 2019

S. crispa extracts are useful for prevention and treatment of human diseases.May 15, 2018

A study of facial wrinkles improvement effect of veratric acid from cauliflower mushroom.Mar 31, 2016

NAD-driven sirtuin activation by Cordyceps sinensis extract: exploring the adaptogenic aotential to promote skin longevity.Apr 11, 2024

A combination of geranium extract, Ganoderma lucidum, Codonopsis pilosula and Angelicae sinensis, improve the condition of cancer patients receiving chemotherapy/radiotherapy. Jun 01, 2009

A combined treatment of Lentinula edodes mycelia and immunotherapy might improve QOL and immunological function in cancer patients.Jun 30, 2016

A dietary supplement with Agaricus sylvaticus fungus is capable of improving the life quality of patients with colorectal cancer in post-surgical phase.Dec 31, 2009

A maitake mushroom extract has beneficial immunomodulatory potential in patients with myelodysplastic syndromes.Oct 28, 2014

A mushroom formula containing Reishi (Ganoderma) has therapeutic activity against herpes genitalis and labialis.Nov 01, 2007

A mushroom formula containing Reishi (Ganoderma) reduces pain in patients with Herpes zoster.Jan 01, 2005

A phase I/II trial of a polysaccharide extract from Maitake mushroom in breast cancer patients.Aug 31, 2009

Agaricus blazei extract in combination with metformin and gliclazide improve insulin resistance in type 2 diabetics. Dec 01, 1999

Agaricus blazei extract normalizes liver function in patients with chronic hepaititis B. Apr 01, 2008

Agaricus blazei increases natural killer cell activity and quality of life in gynecological cancer patients undergoing chemotherapy. Jul 01, 2004

Agaricus brasiliensis has a wide range of therapeutic properties as demonstrated in mice and human subjects. Jun 01, 2008

AGM possibly improves insulin sensitivity and β-cell function and reduces liver damage and inflammation in prediabetic adults.Jul 04, 2021

AHCC improves prognosis of postoperative liver cancer patients. Jul 01, 2002

AHCC may improve survival and prognosis in patients with advanced liver cancer. Mar 01, 2006

Beta glucan found in reishi mushroom is a potent antioxidant against pathogenesis of atherosclerosis in stable angina and high risk patients.Oct 01, 2018

Combined therapy of Red sage (S. miltiorrhizae) and Zhu Ling (P. umbellatus) polysaccharide has therapeutic value in the treatment of chronic hepatitis B.Sep 01, 1993

Consumption of Agaricus brasiliensis KA21 for 12 weeks led to many beneficial improvements in health. Dec 31, 2014

Cordyceps and artemisinin prevent the recurrence of lupus nephritis.Mar 01, 2002

Cordyceps may improve renal function and cellular immune function in chronic kidney failure. Jun 01, 1992

Cordyceps may reduce the need for anti-rejection drugs and improve the outcome of renal transplantation. Jun 01, 2009

Dietary intakes of mushrooms and green tea combine to reduce the risk of breast cancer in Chinese women.Mar 15, 2009

Dongchongxiacao (Cordyceps) can reduce serum markers of airway inflammation of asthmatics.Sep 01, 2005

Effect of Pleurotus ostreatus water extract consumption on blood parameters and cytokine values.Jun 26, 2024

Effect of supplemental antioxidant-based therapy on the oxidative stress level in COVID-19 patients.Feb 28, 2023

Effects of Macuprev® supplementation in age-related macular degeneration.Aug 31, 2019

Efficacy and safety of orally administered Lentinula edodes mycelia extract for patients undergoing cancer chemotherapy.Dec 31, 2010

Efficacy of Cordyceps cicadae mycelium supplementation for amelioration of dry eye symptoms.Dec 31, 2021

Efficacy of Lentinula edodes mycelia extract on chemotherapy-related tasted disorders in pancreatic cancer patients.Dec 31, 2022

Efficacy of Poria cocos extract on sleep quality enhancement.Sep 30, 2023

Fermentation of Pleurotus ostreatus and Ganoderma lucidum mushrooms and their extracts by the gut microbiota of healthy and osteopenic women.Jan 31, 2021

Habitual mushroom intake might help to prevent prostate cancer.Sep 03, 2019

Hericium erinaceus improves mood and sleep disorders in patients affected by overweight or obesity.Dec 31, 2018

Hericium erinaceus intake results in a reduction of depression and anxiety in mice by 4 weeks. Aug 01, 2010

Immunomodulation with β-glucan from Pleurotus ostreatus in patients with endocrine-dependent breast cancer.Nov 16, 2021

Immunomodulatory effect of pleuran (β-glucan from Pleurotus ostreatus) in children with recurrent respiratory tract infections.Jan 31, 2013

Improvement of cognitive functions by oral intake of Hericium erinaceus Dec 31, 2018

Lion's mane improves mild cognitive impairment in human subjects. Mar 01, 2009

Long-term use of combined conventional medicine and Chinese herbal medicine decreases the mortality risk of patients with lung cancer.Jul 31, 2020

Maitake mushroom (Grifola frondosa) extract induces ovulation in patients with polycystic ovary syndrome.Nov 30, 2010

Mushroom mycelium extract was an ineffective treatment for reducing 50% or more the patient prostate specific antigen values.Sep 30, 2010

Mycoprotein and tofu have satiating properties that persist for several hours after a meal.Jan 01, 2006

Oyster mushroom reduced blood glucose and cholesterol in diabetic subjects.Jan 01, 2007

Pleurotus eryngii improves postprandial glycaemia, hunger and fullness perception, and enhances ghrelin suppression in people with metabolically unhealthy obesity.Dec 31, 2021

Prevention of early Alzheimer's disease by Erinacine A-enriched Hericium erinaceus mycelia.Dec 31, 2019

Regular shiitake mushroom consumption resulted in improved immunity.Dec 31, 2014

Reishi (Ganoderma lucidum) safely improves lower urinary tract symptoms in men with benign prostatic hyperplasia. Sep 01, 2008

Reishi (Ganoderma) has significant therapeutic value in patients with FSGS. Jan 01, 2004

Reishi reduces pain from postherpetic neuralgia. Mar 01, 2006

Results suggest that adherence to a diet rich in vegetables, fruits, and typical Japanese foods is associated with a lower probability of having depressive symptoms.Jul 14, 2015

The acute and chronic effects of Lion's mane mushroom supplementation on cognitive function, stress and mood in young adults.Nov 19, 2023

The mushroom Grifola umbellata is superior to mitomycin C in preventing postoperative recurrence of bladder cancer. Sep 05, 2007

The present intervention demonstrated the antioxidation, anti-aging and hepatoprotective nature of Ganoderma lucidum.Nov 30, 2017

These results found increasingly improved symptom score in the AndoSan group.Dec 31, 2015

This study demonstrates that β-glucans from G. lucidum increase the frequency of immune system cells in the peripheral blood.Dec 31, 2017

White button mushroom appears to both impact PSA levels and modulate the biology of biochemically recurrent prostate cancer.Aug 31, 2015

An extract of G. lucidum spores suppressed cholangiocarcinoma migration in vitro through inhibition of TGF-β1-induced EMT.May 14, 2016

Anti-inflammatory effect of mushrooms in dengue-infected human monocytes.Nov 30, 2019

Chaga mushroom extract can inhibit the proliferation of tumor cells.Dec 31, 2013

Combined application of Grifola frondosa and vitamin C induced cell apoptosis and autophagy in vitro.Sep 10, 2017

Ganoderic acids suppress growth and invasive behavior of breast cancer cells.Apr 30, 2008

Protective effects of Cordyceps sinensis exopolysaccharide‑selenium nanoparticles on H2O2-induced oxidative stress in HepG2 cells.May 28, 2022

These preliminary results demonstrated anti-genotoxic properties of Agaricus blazei.Dec 31, 2016

Triterpene ganoderic acid inhibited production of TNF-α and other proinflammatory cytokines by PBMCs and inflamed CD colonic mucosa due to blockage of NF-κB activation.May 18, 2015

verticillin A from Verticillium-infected wild mushrooms as a potent anti-cancer agent that effectively suppresses 5-FU-resistant human colon cancer cells. Aug 31, 2015

Medicinal Mushrooms

View the Evidence:
1236 Abstracts with Medicinal Mushrooms Research