Medium Chain Triglycerides

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17 Diseases Researched for Medium Chain Triglycerides

Name	AC	CK	Focus
Alzheimer's Disease	2	13
Cognitive Decline/Dysfunction	2	13
Epilepsy: Childhood	1	10
Obesity	1	10
Triglycerides: Elevated	1	10
Alcoholic Liver Disease	4	8
Autism	1	3
Autism Spectrum Disorders	1	3
Casein Intolerance	1	3
Gluten Sensitivity	1	3
Amyotrophic lateral sclerosis (ALS)	1	2
Appetite Disorders	1	2
Campylobacter Infections	1	2
Colitis	1	2
Fatty Liver	1	2
Liver Fibrosis	1	2
Athletic Performance	1	0

6 Pharmacological Actions Researched for Medium Chain Triglycerides

Name	AC	CK	Focus
Appetite Depressants	1	10
Cyclooxygenase 2 Inhibitors	2	4
Tumor Necrosis Factor (TNF) Alpha Inhibitor	2	4
Appetite Suppresant	1	2
Hepatoprotective	1	2
NF-kappaB Inhibitor	1	2

Research Articles 18
Cumulative Knowledge Score 29
Overall Research Rating GOOD

View the Evidence:
18 Abstracts with Medium Chain Triglycerides Research

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[+]

A Ketogenic diet is effective in refractory epilepsy of childhood.Dec 13, 1901

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Pubmed Data : Rev Neurol. 2001 Dec 1-15;33(11):1010-4. PMID: 11785025

Study Type : Human Study

Additional Links

Substances : Medium Chain Triglycerides

Diseases : Epilepsy: Childhood

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

[+]

Coconut oil has less satiating properties than medium chain triglyceride oil.Sep 30, 2017

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Pubmed Data : Physiol Behav. 2017 Oct 1 ;179:422-426. Epub 2017 Jul 6. PMID: 28689741

Article Published Date : Sep 30, 2017

Study Type : Human Study

Additional Links

Substances : Medium Chain Triglycerides, Virgin Coconut Oil

Diseases : Obesity

Pharmacological Actions : Appetite Depressants

Additional Keywords : Anti-Obesity Agents

[+]

Medium Chain Triglycerides (coconut fat) increase cognitive performance in Alzheimer's disease.Mar 22, 2006

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Pubmed Data : Neurobiol Aging. 2004 Mar;25(3):311-4. PMID: 15123336

Article Published Date : Mar 22, 2006

Study Type : Human Study

Additional Links

Substances : Coconut, Coconut Oil, Medium Chain Triglycerides

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction

[+]

Omega-3 fatty acids and medium-chain triglycerides ameloriate high triglycerides in human subjects. Feb 12, 2010

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Pubmed Data : Ann Nutr Metab. 2010 Feb 12;56(3):170-175. Epub 2010 Feb 12. PMID: 20150726

Article Published Date : Feb 12, 2010

Study Type : Human Study

Additional Links

Substances : Medium Chain Triglycerides, Omega-3 Fatty Acids

Diseases : Triglycerides: Elevated

[+]

Autism and Dietary Therapy: Case Report and Review of the Literature.May 09, 2013

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Pubmed Data : J Child Neurol. 2013 May 10. Epub 2013 May 10. PMID: 23666039

Article Published Date : May 09, 2013

Study Type : Human: Case Report

Additional Links

Substances : Medium Chain Triglycerides

Diseases : Autism, Autism Spectrum Disorders, Casein Intolerance, Gluten Sensitivity

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic, Dietary Modification: Wheat/Gluten Free

Problem Substances : Casein, Wheat

[+]

Caprylic triglyceride impove certain cases of mild-to-moderate Alzheimer's disease.Dec 31, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

Article Published Date : Dec 31, 2012

Study Type : Human: Case Report

Additional Links

Substances : Caprylic Acid, Coconut Oil, Medium Chain Triglycerides

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction

[+]

A ketogenic diet in combination with nutritrional supplementation has remarkable therapeutic properties in a rodent model of ALS. Dec 31, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2014 ;9(7):e103526. Epub 2014 Jul 25. PMID: 25061944

Article Published Date : Dec 31, 2013

Study Type : Animal Study

Additional Links

Substances : Arginine-alpha-ketoglutarate (AAKG), Coenzyme Q10, GABA (gamma-Aminobutyric Acid), Medium Chain Triglycerides

Diseases : Amyotrophic lateral sclerosis (ALS)

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

[+]

Caprylic acid inhibits feeding possibly through increased fat burning in the liver.Feb 28, 2006

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Pubmed Data : Physiol Behav. 2006 Feb 28;87(2):388-95. Epub 2005 Dec 20. PMID: 16360711

Article Published Date : Feb 28, 2006

Study Type : Animal Study

Additional Links

Substances : Caprylic Acid, Medium Chain Triglycerides

Diseases : Appetite Disorders

Pharmacological Actions : Appetite Suppresant

[+]

Caprylic acid reduces Campylobacter species colonization in chicks.Jul 01, 2008

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Pubmed Data : Appl Environ Microbiol. 2008 Jul;74(14):4564-6. Epub 2008 May 23. PMID: 18502935

Article Published Date : Jul 01, 2008

Study Type : Animal Study

Additional Links

Substances : Caprylic Acid, Medium Chain Triglycerides

Diseases : Campylobacter Infections

[+]

Dietary medium-chain triglycerides attenuate liver fat deposits in growing rats with protein malnutrition. Jan 01, 2011

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Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2011 ;57(2):138-43. PMID: 21697632

Article Published Date : Jan 01, 2011

Study Type : Animal Study

Additional Links

Substances : Medium Chain Triglycerides

Diseases : Fatty Liver

Pharmacological Actions : Hepatoprotective

[+]

Dietary saturated fatty acids down-regulate cyclooxygenase-2 and tumor necrosis factor alfa and reverse fibrosis in alcohol-induced liver disease in the rat.Dec 01, 1997

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Pubmed Data : Hepatology. 1997 Dec;26(6):1538-45. PMID: 9397995

Article Published Date : Dec 01, 1997

Study Type : Animal Study

Additional Links

Substances : Medium Chain Triglycerides, Palm Oil, Saturated fatty acids

Diseases : Alcoholic Liver Disease, Liver Fibrosis

Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Beneficial Saturated Fats, Disease Reversal

[+]

Medium chain triglycerides and vitamin E reduce the severity of established experimental alcoholic liver disease.Jun 01, 1996

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Pubmed Data : J Pharmacol Exp Ther. 1996 Jun;277(3):1694-700. PMID: 8667240

Article Published Date : Jun 01, 1996

Study Type : Animal Study

Additional Links

Substances : Medium Chain Triglycerides, Vitamin E

Diseases : Alcoholic Liver Disease

[+]

Medium Chain Triglycerides have hepatoprotective effect in alcoholic liver disease.Apr 01, 2004

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Pubmed Data : J Nutr. 2004 Apr;134(4):904-12. PMID: 15051845

Article Published Date : Apr 01, 2004

Study Type : Animal Study

Additional Links

Substances : Medium Chain Triglycerides

Diseases : Alcoholic Liver Disease

[+]

Partial replacement with dietary omega 6 fatty acids with medium chain triglycerides decreases the incidence of spontaneous colitis in IL-10 deficient mice. Mar 01, 2009

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Pubmed Data : J Nutr. 2009 Mar;139(3):603-10. Epub 2009 Jan 6. PMID: 19126671

Article Published Date : Mar 01, 2009

Study Type : Animal Study

Additional Links

Substances : Medium Chain Triglycerides

Diseases : Colitis

Therapeutic Actions : Dietary Modification: Alteration of Dietary Fat Types and/or Ratios

[+]

Saturated fatty acids, palm oil and medium chain triglycerides, reverse inflammatory and fibrotic changes in rat liver despite continued ethanol administration.Nov 01, 2001

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Pubmed Data : J Pharmacol Exp Ther. 2001 Nov;299(2):638-44. PMID: 11602676

Article Published Date : Nov 01, 2001

Study Type : Animal Study

Additional Links

Substances : Medium Chain Triglycerides, Palm Oil, Saturated fatty acids

Diseases : Alcoholic Liver Disease

Pharmacological Actions : Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Beneficial Saturated Fats

[+]

Hypometabolism as a therapeutic target in Alzheimer's disease.Dec 31, 2007

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Neurosci. 2008 ;9 Suppl 2:S16. Epub 2008 Dec 3. PMID: 19090989

Article Published Date : Dec 31, 2007

Study Type : Review

Additional Links

Substances : Ketone Bodies, Medium Chain Triglycerides

[+]

Review: Metabolism of coconut fats and its potential benefits.Jun 04, 2006

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Pubmed Data : 2006 Jun;51(2):47-51. Epub 2006 Jun. PMID: 17180807

Article Published Date : Jun 04, 2006

Study Type : Review

Additional Links

Substances : Coconut, Coconut Oil, Medium Chain Triglycerides

Additional Keywords : Coconut, coconut oil, MCT oil

[+]

Medium-chain triglycerides improve endurance capacity in mice.Mar 01, 1995

Click here to read the entire abstract

Pubmed Data : J Nutr. 1995 Mar;125(3):531-9. PMID: 7876928

Article Published Date : Mar 01, 1995

Additional Links

Substances : Medium Chain Triglycerides

Diseases : Athletic Performance

Copyright: alila / 123RF Stock Photo

Research Articles 18
Cumulative Knowledge Score 29
Overall Research Rating GOOD

Medium Chain Triglycerides Related Articles

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MCTs, the primary type of fat found within coconut oil, have been found to boost cognitive performance in older adults suffering from memory disorders as serious as Alzheimer's -- and not after months or even days of treatment, but after a single 40 ml dose!

How Coconut Oil May Rescue the Brain From Alzheimer's Disease

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Anecdotal reports claim coconut oil produces remarkable recoveries from Alzheimer's disease, but is there research to support this? Now, one study published in the Journal of Alzheimer's Disease shows that a mechanism for coconut oil's brain rescuing properties does in fact exist

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The Alzheimer's brain can't handle glucose effectively, which is why this unique saturated fat may hold the key to improving and even reversing the condition in some patients

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