Melatonin

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398 Diseases Researched for Melatonin
NameACCKFocus
Oxidative Stress98264Locked
Sleep Disorders18136Locked
Breast Cancer47119Locked
Delirium7102Locked
Inflammation3391Locked
Alzheimer's Disease3280Locked
Parkinson's Disease1463Locked
Hormone Imbalances: Low Melatonin958Locked
Insomnia652Locked
Obesity1952Locked
Circadian Dysregulation1050Locked
Testicular Injury: Chemical/Metal Induced1649Locked
Epilepsy848Locked
Neurodegenerative Diseases1945Locked
Lipid Peroxidation1342Locked
Depression1341Locked
C-Reactive Protein340Locked
Multiple Sclerosis1040Locked
Cancers: All1139Locked
Coronavirus Infection1039Locked
Diabetes Mellitus: Type 21139Locked
Bisphenol Toxicity2136Locked
Headache734Locked
Chronic Pain533Locked
Periodontitis733Locked
Muscle Damage: Exercise-Induced532Locked
Sepsis1132Locked
Chemotherapy and Radiation Toxicity931Locked
Tinnitus330Locked
Stroke: Ischemic628Locked
Aging1527Locked
Brain Injury: Traumatic627Locked
Prostate Cancer625Locked
Jet Lag423Locked
Liver Cancer1323Locked
Metabolic Syndrome X222Locked
Nocturia322Locked
Gastroesophageal Reflux321Locked
Headache: Migraine321Locked
Lipopolysaccharide-Induced Toxicity1121Locked
Burns120Locked
Cancer: Fatigue220Locked
Cardiac Surgery220Locked
Chemically-Induced Liver Damage620Locked
Cognitive Decline/Dysfunction620Locked
Delayed Sleep Phase Disorder120Locked
Depressive Disorder220Locked
Insulin Resistance620Locked
Multiple Sclerosis: Relapsing-Remitting 220Locked
Osteoporosis720Locked
Overweight 120Locked
Postoperative Recovery220Locked
Purpura: Thrombocytopenic220Locked
Thrombocytopenia220Locked
Diabetic Nephropathy619Locked
Aging: Brain 918Locked
Aluminum Toxicity 917Locked
Hypertension517Locked
Liver Damage517Locked
DNA damage816Locked
Infertility: Male816Locked
Ovarian Cancer515Locked
Brain: Oxidative Stress814Locked
Colorectal Cancer514Locked
Fibromyalgia414Locked
Liver Fibrosis514Locked
Polycystic Ovary Syndrome314Locked
Squamous cell carcinoma414Locked
Aging Skin313Locked
Anxiety813Locked
Benzo[a]pyrene-induced Toxicity 313Locked
Irritable Bowel Syndrome413Locked
Pancreatitis313Locked
Spinal Cord Injuries713Locked
Autism212Locked
Breast Cancer: Metastatic212Locked
Chemotherapy-Induced Toxicity: Cyclophosphamide212Locked
Heart Failure212Locked
Mitochondrial Dysfunction 712Locked
Oral Mucositis212Locked
Periodontal Diseases312Locked
Scoliosis212Locked
Anxiety Disorders211Locked
Bipolar Disorder211Locked
Chemotherapy-Induced Toxicity: Cisplatin611Locked
Osteoarthritis: Knee211Locked
Pneumonia211Locked
Prostatic Hyperplasia: Benign211Locked
Radiation Induced Illness611Locked
Radiation-Induced Illness: Radioiodine (Iodine-131)211Locked
Retinal Diseases211Locked
Septic Shock211Locked
Skin Diseases211Locked
Tongue Cancer211Locked
Abdominal Obesity (Midsection Fat)110Locked
Aneurysmal subarachnoid hemorrhage (SAH)110Locked
Asperger Syndrome110Locked
Athletic Performance110Locked
Bone Fractures110Locked
Brain Inflammation 610Locked
Cataract110Locked
Cesarean Section110Locked
Chronic Fatigue Syndrome110Locked
Chronic Obstructive Pulmonary Disease110Locked
Cirrhosis110Locked
Coronary Artery Disease110Locked
Coronary Bypass Surgery110Locked
Cortisol: High110Locked
Depression: Breast Cancer Related110Locked
Dyspepsia110Locked
Erythema110Locked
Fatigue110Locked
Female110Locked
Gastric Cancer810Locked
Genital Herpes110Locked
Graves Disease110Locked
Helicobacter Pylori Infection110Locked
Hemodialysis110Locked
Human Growth Hormone: Enhancement110Locked
Melasma110Locked
Osteoarthritis: Hip 110Locked
Osteopenia110Locked
Osteosarcoma610Locked
Pain: Post-operative110Locked
Premature Birth110Locked
Retinal Sensitivity110Locked
Sclerosis: Systemic110Locked
Skin Diseases: Photo-Aging110Locked
Thrombosis110Locked
Weight Gain: Drug-Induced110Locked
Endothelial Dysfunction69Locked
Infertility39Locked
Myocardial Infarction59Locked
Cadmium Poisoning 58Locked
Cancer Metastasis48Locked
Cerebral Ischemia58Locked
Diabetes Mellitus: Type 158Locked
Endometriosis68Locked
Fluoride Toxicity 58Locked
Glyphosate Toxicity48Locked
High Fat Diet48Locked
Kidney Damage: Chemically-Induced48Locked
Liver Injury: Ischemia/reperfusion 58Locked
Lung Injury: Acute58Locked
Mobile Phone-Induced Oxidative Stress48Locked
Myocardial Ischemia48Locked
Radiation48Locked
Cardiovascular Diseases67Locked
Chemotherapy-Induced Toxicity: Doxorubicin47Locked
Colon Cancer67Locked
Hypoxia37Locked
Kidney Damage47Locked
Liver Disease47Locked
Pesticide Toxicity 47Locked
Sperm Quality: Low27Locked
Alcohol Toxicity 36Locked
Cardiomyopathy46Locked
Cerebral Hypoperfusion36Locked
Cervical Cancer56Locked
Colitis36Locked
Diabetic Complications36Locked
Dysbiosis36Locked
High Fructose Diet36Locked
Ischemia46Locked
Kidney Damage: Drug-Induced36Locked
Lung Cancer26Locked
Memory Disorders36Locked
Osteoarthritis46Locked
Stress36Locked
Stroke: Attenuation/Recovery 56Locked
Air Pollution Linked Toxicity35Locked
Amyotrophic Lateral Sclerosis55Locked
Atherosclerosis35Locked
Breast Cancer: Triple Negative 45Locked
Diabetes: Cognitive Dysfunction25Locked
Glioblastoma55Locked
Huntington Disease45Locked
Neuroblastoma15Locked
Osteoporosis: Inflammation Induced15Locked
Pancreatic Cancer45Locked
Traumatic Brain Injury35Locked
Ultraviolet Radiation Induced Damage45Locked
Acrylamide-induced toxicity24Locked
Aging: Immunosenecence34Locked
Alcoholic Liver Disease24Locked
Chemotherapy-Induced Kidney Damage24Locked
Chemotherapy-Induced Toxicity34Locked
Chemotherapy-Induced Toxicity: Gentamicin24Locked
Dementia34Locked
Diabetes: Oxidative Stress24Locked
Diabetic Retinopathy24Locked
Drug-Induced Toxicity: Methotrexate24Locked
Electromagnetic Radiation Mitigation24Locked
Encephalitis24Locked
Hypertension: Pulmonary24Locked
Kidney Diseases24Locked
Leukemia34Locked
Liver Cirrhosis24Locked
Lung Damage24Locked
Macular Degeneration44Locked
Memory Disorders: Sleep Deprivation Induced24Locked
Metabolic Diseases24Locked
Microplastic Toxicity24Locked
Neonatal Stroke24Locked
Nicotine/Tobacco Toxicity 34Locked
Pineal Gland Calcification 34Locked
Pregnancy Complications24Locked
Psychiatric Disorders34Locked
Schizophrenia34Locked
Subarachnoid hemorrhage34Locked
Arsenic Poisoning23Locked
Brain Damage23Locked
Brain Ischemia23Locked
Breast Cancer: Estrogen33Locked
Breast Cancer: estrogen receptor alpha-positive23Locked
Endotoxemia23Locked
Gastric Ulcer23Locked
Head and Neck Cancer23Locked
Kidney Stones13Locked
Nephrolithiasis13Locked
Oral Cancer33Locked
Pituitary Tumours23Locked
Systemic Lupus Erythematosus33Locked
Ulcerative Colitis23Locked
Acetaminophen (Tylenol) Toxicity 12Locked
Acute Respiratory Distress Syndrome22Locked
Aflatoxicosis12Locked
Aging: Heart12Locked
Amnesia12Locked
Amyotrophic lateral sclerosis (ALS)22Locked
Asthma12Locked
Atopic Dermatitis12Locked
Autism Spectrum Disorders22Locked
Autoimmune Diseases22Locked
Benzene Toxicity12Locked
Bile Duct Injury12Locked
Blood Diseases12Locked
Bone Diseases12Locked
Breast Cancer: Lung Metastasis12Locked
Cancer: Prostate12Locked
Cardiac Hypertrophy12Locked
Cardiovascular Disease12Locked
Cataract: Radiation-Induced12Locked
Cell Phone Induced Disease12Locked
Chemotherapy-Induced Toxicity: 5-fluorouracil 12Locked
Chemotherapy-Induced Toxicity: Epirubicin12Locked
Chemotherapy-Induced Toxicity: Oxaliplatin12Locked
Cholestasis12Locked
Chronic Kidney Disease (CKD)22Locked
Cocaine Addiction12Locked
Cocaine Withdrawal12Locked
Colon Cancer: Prevention12Locked
Coronavirus Disease (Covid-19)22Locked
Cough12Locked
Coxsackievirus Infections12Locked
Degenerative Disk Disease12Locked
Demyelinating Diseases12Locked
Depression12Locked
Depression: Stress Related12Locked
Diabetes12Locked
Drug Toxicity: Methotrexate12Locked
Drug-Induced Toxicity: Bisphosphonates12Locked
Drug-Induced Toxicity: Indomethacin12Locked
Edema12Locked
Endometrial Cancer12Locked
Estrogen Deficiency12Locked
Fibrosis12Locked
Fructose-Induced Toxicity 12Locked
Glaucoma32Locked
Gliomas12Locked
Glutathione Deficiency 12Locked
HIV Drug-Induced Toxicity 12Locked
Headache: Cluster22Locked
Heart Disease12Locked
Hepatic Steatosis12Locked
Herbicide Toxicity12Locked
High Homocysteine12Locked
High Sugar Diet12Locked
Hydrogen Peroxide Induced Toxicity22Locked
Hyperalgesia12Locked
Hyperbilirubinemia: Hereditary12Locked
Hypercholesterolemia12Locked
Hyperglycemia12Locked
Hyperlipidemia12Locked
Hyperthyroidism12Locked
Hypothyroidism12Locked
Hypoxia: Brain12Locked
Immune Disorders: Low Immune Function12Locked
Inflammation: Brain12Locked
Influenza12Locked
Intestinal Ischemia12Locked
Kidney Cancer22Locked
Kidney Failure12Locked
Kidney Fibrosis22Locked
Learning disorders12Locked
Leiomyosarcoma12Locked
Liver Damage: Drug-Induced12Locked
Low Immune Function: Natural Killer Cells12Locked
Lymphoma: B-Cell22Locked
Malaria12Locked
Melanoma22Locked
Morphine Tolerance/Dependence12Locked
Multi-Organ Failure12Locked
Myocarditis: Viral 12Locked
Necrotising enterocolitis12Locked
Neural Tube Defects12Locked
Neuralgia: Post Herpetic12Locked
Neuritis: Brachial Plexus12Locked
Nonalcoholic fatty liver disease (NAFLD)12Locked
Obstructive Nephropathy12Locked
Optic Neuritis12Locked
Ovarian Failure12Locked
Ovariectomy Associated Adverse Changes12Locked
Plasmodium Infections12Locked
Prediabetes12Locked
Prenatal Chemical Exposures12Locked
Prenatal Nutrition: Prevention of Problems12Locked
Psoriasis12Locked
Quality of Life: Poor12Locked
Radiation-Induced Illness: Cesium-137 Exposure12Locked
Rheumatoid Arthritis22Locked
Sciatic Nerve Crush Injury12Locked
Sciatica12Locked
Sleep Apnea: Central12Locked
Snake Bite: Venom Toxicity 12Locked
Substance Abuse12Locked
Surgery: Anesthesiology12Locked
Testicular Injury: Formaldehyde-Induced12Locked
Testicular Injury: Nicotine-Induced12Locked
Tumors22Locked
Vaginal Cancer12Locked
Wound Healing12Locked
Acute Myeloid Leukemia11Locked
Acute T cell Leukemias11Locked
Acute lymphoblastic leukemia (ALL)11Locked
Amphetamine Addiction/Withdrawal11Locked
Animal Cancers11Locked
Asphyxia11Locked
Bacterial Infections11Locked
Brain Edema11Locked
Cancers: Drug Resistant11Locked
Carcinoma: Non-Small-Cell Lung11Locked
Chemotherapy11Locked
Chemotherapy-Induced Toxicity: Arsenic Trioxide11Locked
Chronic Disease11Locked
Crohn's Disease11Locked
Dysmenorrhea11Locked
Ebola Virus Infections11Locked
Encephalomyelitis11Locked
Encephalopathy11Locked
Encephalopathy: Hypoxic11Locked
Endocrine Diseases11Locked
Endothelial Damage11Locked
Esophageal Cancer11Locked
Estrogen Dominance11Locked
Eye Damage11Locked
Fractures: Bone11Locked
Fragile X Syndrome11Locked
Gallbladder Inflammation11Locked
Gallstones11Locked
Gastritis11Locked
Glioma11Locked
Heavy Metal Toxicity11Locked
Herpes Simplex Virus Type 111Locked
Inflammatory Bowel Diseases11Locked
Leiomyoma11Locked
Liver Damage: Aflatoxin-Induced11Locked
Lung Injury: Smoke-Induced11Locked
Lymphoma11Locked
Mastitis11Locked
Migraine Disorders11Locked
Migraines11Locked
Mitochondrial Diseases11Locked
Mood Disorders11Locked
Myasthenia Gravis11Locked
Napthalene-Induced Toxicity11Locked
Nasopharyngeal Cancer11Locked
Non-Small-Cell Lung Carcinoma11Locked
Organ Transplantation11Locked
Organ Transplantation: Liver11Locked
Pancreatic Diseases11Locked
Parasitic Diseases11Locked
Photooxidative Stress11Locked
Pineal Gland Diseases11Locked
Post-Traumatic Stress Disorders (PTSD)11Locked
Proliferative Vitreoretinopathy (PVR)11Locked
Pulmonary Fibrosis11Locked
Renal Cancer11Locked
Retinopathy of Prematurity11Locked
Sarcoma: Ewing's11Locked
Sjogren's Syndrome11Locked
Stroke11Locked
Stroke: Hemorrhagic 11Locked
Thyroid Cancer11Locked
Vaccine-induced Toxicity 11Locked
Wound Healing: Delayed11Locked
Abdominal Adhesions10Locked
Sarcoidosis10Locked
129 Pharmacological Actions Researched for Melatonin
NameACCKFocus
Antioxidants239589Locked
Anti-Inflammatory Agents142345Locked
Neuroprotective Agents131332Locked
Hepatoprotective4190Locked
Antiproliferative 5788Locked
Anti-Apoptotic5083Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor2983Locked
Apoptotic5781Locked
Radioprotective2378Locked
Renoprotective3269Locked
Antidepressive Agents1368Locked
Cardioprotective2967Locked
Analgesics1166Locked
Interleukin-6 Downregulation1355Locked
Chemotherapeutic1754Locked
Prophylactic Agents854Locked
Chemoprotective Agents1851Locked
Gastrointestinal Agents1648Locked
NF-kappaB Inhibitor2642Locked
Interleukin-1 beta downregulation2037Locked
Anti-metastatic2835Locked
Anticonvulsants435Locked
Malondialdehyde Down-regulation1333Locked
Immunomodulatory2331Locked
Hypoglycemic Agents730Locked
Nrf2 activation1829Locked
Chemosensitizer2328Locked
Brain-derived neurotrophic factor modulator426Locked
Regenerative825Locked
Superoxide Dismutase Up-regulation1325Locked
Cyclooxygenase 2 Inhibitors1224Locked
Cytoprotective1323Locked
Insulin Sensitizers322Locked
Secretagogue322Locked
Antinoceceptive 120Locked
Osteogenic419Locked
Anti-Fibrotic818Locked
Antihypertensive Agents618Locked
Antiviral Agents718Locked
Gastroprotective918Locked
Hypolipidemic518Locked
Tumor Suppressor Protein p53 Upregulation1518Locked
Angiogenesis Inhibitors1117Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor1114Locked
Heme oxygenase-1 up-regulation912Locked
Vascular Endothelial Growth Factor Inhibitors612Locked
Chemopreventive711Locked
Genoprotective511Locked
Proton Pump Inhibitor211Locked
Adiponectin upregulation110Locked
Anti-Anxiety Agents610Locked
Antineoplastic Agents810Locked
Anxiolytic110Locked
Bcl-2 protein down-regulation710Locked
Cell cycle arrest1010Locked
Hypnotics and Sedatives110Locked
Insulin-Like Growth Factor Inhibition/Downregulation110Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor510Locked
MicroRNA modulator810Locked
Sedative effects110Locked
Vasodilator Agents110Locked
Anticarcinogenic Agents59Locked
Antioxidant39Locked
Osteoprotective 69Locked
Autophagy Inhibitors58Locked
Interleukin-17 downregulation47Locked
Cyclin D1 Down-Regulation36Locked
Pancreato Protective Agents36Locked
Autophagy Up-regulation45Locked
Fertility Agents: Male35Locked
Nitric Oxide Inhibitor15Locked
Prostaglandin PGE2 downregulation15Locked
Anti-Angiogenic34Locked
Anticholesteremic Agents24Locked
Calcium Channel Blockers24Locked
Catalase Up-Regulation24Locked
Glutathione Upregulation 24Locked
Interleukin-12 downregulation24Locked
Neurogenesis34Locked
Photoprotective34Locked
Radiosensitizer44Locked
Antimutagenic Agents23Locked
Aromatase Inhibitors33Locked
Caspase-3 Activation23Locked
Chondroprotective23Locked
DNA Repair Up-regulation23Locked
Detoxifier23Locked
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor33Locked
Immunostimulatory33Locked
Interleukin-8 downregulation33Locked
Transforming growth factor beta (TGF-β) inhibitor23Locked
Wnt/β-catenin signaling pathway modulation23Locked
Acetylcholinesterase Inhibitor12Locked
Adenosine Monophosphate (AMP)-activated Protein Kinase (AMPK12Locked
Anti-Proliferative12Locked
Anti-Ulcer Agents12Locked
Anti-atherogenic12Locked
BRCA-1 Downregulation22Locked
Fertility Agents12Locked
Heat Shock Protein Down-Regulation12Locked
Interleukin-10 downregulation12Locked
Interleukin-4 downregulation12Locked
Matrix Metalloproteinase-13 (MMP-13) Inhibitor12Locked
Matrix metalloproteinase-8 (MMP-8) inhibitor12Locked
Neuroplasticity enhancement12Locked
Neurorestorative12Locked
Postaglandin PGE2 downregulation 12Locked
Receptor-Related Orphan Receptor (ROR)-Alpha1 Inhibitor12Locked
SIRT1 Activator12Locked
12-lipoxygenase (12-LOX) Inhibitor11Locked
Apaf-1/caspase-dependent apoptotic pathway activator11Locked
Bax/Bcl2 ratio: Increase11Locked
Caspase-9 Activation11Locked
Cell Differentiation Inducer11Locked
Cyclooxygenase Inhibitors11Locked
Drug synergy11Locked
Enzyme Inhibitors11Locked
Immunomodulatory: Th17 downregulation11Locked
Matrix metalloproteinase-1 (MMP-1) inhibitor11Locked
P21 Activation11Locked
P38 Mitogen-Activated Protein Kinase Modulator11Locked
PI3K/Akt/signaling suppression11Locked
Selective estrogen enzyme modulator (SEEM)11Locked
Telomerase Inhibitor11Locked
Telomerase Upregulation11Locked
Telomere Protective11Locked
Tumor Necrosis Factor (TNF) Alpha Enhancer11Locked
Vascular Endothelial Growth Factor A Inhibitor11Locked
p300/NF-κB down-regulation11Locked
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View the Evidence:
903 Abstracts with Melatonin Research

[+]
Pubmed Data : Inflammopharmacology. 2022 Mar 15. Epub 2022 Mar 15. PMID: 35290552
Study Type : Meta Analysis, Review
Additional Links
Substances : Melatonin
Diseases : Periodontitis
Additional Keywords : Risk Reduction
[+]
Pubmed Data : Curr Neuropharmacol. 2022 May 6. Epub 2022 May 6. PMID: 35524672
Study Type : Meta Analysis, Review
Additional Links
Substances : Melatonin
Diseases : Delirium
Pharmacological Actions : Neuroprotective Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Endocrinol (Lausanne). 2023 ;14:1184745. Epub 2023 Aug 28. PMID: 37701901
Study Type : Meta Analysis, Review
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Psychiatry. 2022 ;13:737972. Epub 2022 Mar 17. PMID: 35370838
Study Type : Meta Analysis, Review
Additional Links
Substances : Melatonin
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]
Pubmed Data : Seizure. 2024 Feb 23 ;117:133-141. Epub 2024 Feb 23. PMID: 38417212
Study Type : Meta Analysis, Review
Additional Links
Substances : Melatonin
Diseases : Epilepsy
Pharmacological Actions : Anticonvulsants
[+]
Pubmed Data : Horm Mol Biol Clin Investig. 2020 Nov 11. Epub 2020 Nov 11. PMID: 33185572
Study Type : Meta Analysis, Review
Additional Links
Substances : Melatonin
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
[+]
Pubmed Data : Curr Pharm Des. 2016 Nov 29. Epub 2016 Nov 29. PMID: 27897121
Study Type : Meta Analysis, Review
Additional Links
Substances : Melatonin
Diseases : Overweight
[+]
Pubmed Data : Pharmacol Res. 2020 Sep 29 ;161:105210. Epub 2020 Sep 29. PMID: 33007423
Study Type : Meta Analysis, Review
Additional Links
Substances : Melatonin
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
[+]
Pubmed Data : Sleep. 2010 Dec;33(12):1605-14. PMID: 21120122
Study Type : Meta Analysis
Additional Links
Substances : Melatonin
[+]
Pubmed Data : Altern Ther Health Med. 2024 Mar 22. Epub 2024 Mar 22. PMID: 38518134
Study Type : Meta Analysis
Additional Links
Substances : Melatonin
Diseases : Delirium
Additional Keywords : Risk Reduction
[+]
Pubmed Data : J Pineal Res. 2005 Nov;39(4):360-6. PMID: 16207291
Study Type : Meta Analysis
Additional Links
Substances : Melatonin
Diseases : Cancers: All
[+]
Pubmed Data : Mol Neurobiol. 2015 Jul 21. Epub 2015 Jul 21. PMID: 26189834
Study Type : Meta Analysis
Additional Links
Substances : Melatonin
Diseases : Delirium
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Geriatr. 2019 Oct 16 ;19(1):272. Epub 2019 Oct 16. PMID: 31619178
Study Type : Meta Analysis, Review
Additional Links
Substances : Melatonin
Diseases : Delirium
Pharmacological Actions : Neuroprotective Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2020 Nov 27 ;9(12). Epub 2020 Nov 27. PMID: 33261180
Study Type : Meta Analysis, Review
Additional Links
Substances : Melatonin
Diseases : Burns
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Nov 21 ;8(59):100582-100592. Epub 2017 Oct 5. PMID: 29246003
Study Type : Meta Analysis, Review
[+]
Pubmed Data : J Neurotrauma. 2018 Jun 14. Epub 2018 Jun 14. PMID: 29901413
Study Type : Meta Analysis, Review
Additional Links
Substances : Melatonin
Pharmacological Actions : Neuroprotective Agents
[+]
Pubmed Data : Front Neuroendocrinol. 2018 Jun 14. Epub 2018 Jun 14. PMID: 29908879
Study Type : Meta Analysis, Review
Additional Links
Substances : Melatonin
Diseases : Sleep Disorders
[+]
Pubmed Data : Neurol Sci. 2015 Aug 9. Epub 2015 Aug 9. PMID: 26255301
Study Type : Meta Analysis
[+]
Pubmed Data : Inflammopharmacology. 2018 Jun 15. Epub 2018 Jun 15. PMID: 29907916
Study Type : Meta Analysis, Review
Additional Links
Substances : Melatonin
[+]
Pubmed Data : Curr Neurovasc Res. 2024 Mar 8. Epub 2024 Mar 8. PMID: 38468527
Study Type : Human Study
Additional Links
Substances : Melatonin
[+]
Pubmed Data : J Pineal Res. 2006 Oct;41(3):195-200. PMID: 16948779
Study Type : Human Study
[+]
Pubmed Data : Chronobiol Int. 1998 Nov;15(6):655-66. PMID: 9844753
Study Type : Human Study
Additional Links
Substances : Melatonin
Diseases : Jet Lag
Additional Keywords : Less is More
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ir J Med Sci. 2022 Aug ;191(4):1913-1924. Epub 2021 Sep 1. PMID: 34468959
Study Type : Human Study
Additional Links
Substances : Melatonin
Diseases : Septic Shock
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Infect Dis. 2022 Jan ;114:79-84. Epub 2021 Oct 12. PMID: 34653660
Study Type : Human Study
Additional Links
Substances : Melatonin
Additional Keywords : Mortality
[+]
Pubmed Data : J Neonatal Perinatal Med. 2015 Oct 9. Epub 2015 Oct 9. PMID: 26485549
Study Type : Human Study
Additional Links
Substances : Melatonin
Diseases : Sepsis
[+]
Pubmed Data : J Pineal Res. 2011 Apr ;50(3):267-71. Epub 2010 Dec 16. PMID: 21158908
Study Type : Human Study
Additional Links
Substances : Melatonin
Diseases : Fibromyalgia
Additional Keywords : Significant Treatment Outcome
Problem Substances : Fluoxetine (trade name Prozac)
[+]
Pubmed Data : Oxid Med Cell Longev. 2021 ;2021:6308255. Epub 2021 Nov 19. PMID: 34840669
Study Type : Human Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Antioxidants
[+]
Pubmed Data : J Dermatol Sci. 2016 Aug 9. Epub 2016 Aug 9. PMID: 27543364
Study Type : Human Study
Additional Links
Substances : Melatonin
Additional Keywords : Dose Response
[+]
Pubmed Data : J Obstet Gynaecol India. 2019 Oct ;69(5):436-443. Epub 2019 Apr 24. PMID: 31598047
Study Type : Human Study
Additional Links
Substances : Melatonin
Diseases : Cesarean Section
Additional Keywords : Risk Reduction
[+]
Pubmed Data : Sleep. 2016 Oct 10. Epub 2016 Aug 10. PMID: 27748241
Study Type : Human Study
Additional Links
Substances : Melatonin
Therapeutic Actions : Light Therapy
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Gen Psychiatry. 2011 Jan ;68(1):61-70. PMID: 21199966
Study Type : Human Study
Additional Links
Substances : Melatonin
Therapeutic Actions : Light Therapy
Pharmacological Actions : Antidepressive Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sleep Sci. 2016 Oct-Dec;9(4):285-288. Epub 2016 Aug 10. PMID: 28154742
Study Type : Human Study
Additional Links
Substances : Melatonin
[+]
Pubmed Data : J Child Adolesc Psychopharmacol. 2017 Mar 24. Epub 2017 Mar 24. PMID: 28339282
Study Type : Human Study
Additional Links
Substances : Melatonin
Additional Keywords : Risk Reduction
Problem Substances : Olanzapine
[+]
Pubmed Data : Klin Med (Mosk). 2013 ;91(3):50-3. PMID: 23789453
Study Type : Human Study
Additional Links
Substances : Melatonin
Additional Keywords : Plant Extracts
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Anesthesiol. 2022 Oct 15 ;22(1):318. Epub 2022 Oct 15. PMID: 36243712
Study Type : Human Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Analgesics
Additional Keywords : Natural Substances Versus Drugs
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Ter. 2020 ;171(5):e393-e398. PMID: 32901780
Study Type : Human Study
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Study Type : Human Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Neuroprotective Agents
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Study Type : Human Study
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Pubmed Data : Brain Behav. 2023 Feb ;13(2):e2860. Epub 2023 Jan 1. PMID: 36588283
Study Type : Human Study
Additional Links
Substances : Melatonin
Diseases : Epilepsy
Pharmacological Actions : Anticonvulsants
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Pubmed Data : Clin Neurol Neurosurg. 2024 Mar ;238:108165. Epub 2024 Feb 8. PMID: 38428060
Study Type : Human Study
Additional Links
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Pharmacological Actions : Analgesics
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomedicines. 2023 Apr 4 ;11(4). Epub 2023 Apr 4. PMID: 37189706
Study Type : Human Study
Additional Links
Substances : Melatonin
Diseases : Genital Herpes
Pharmacological Actions : Analgesics, Antiviral Agents
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Pubmed Data : Heart Surg Forum. 2021 Oct 21 ;24(5):E893-E897. Epub 2021 Oct 21. PMID: 34730495
Study Type : Human Study
Additional Links
Substances : Melatonin
Diseases : Delirium
Pharmacological Actions : Neuroprotective Agents
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Pubmed Data : Mult Scler J Exp Transl Clin. 2021 Oct ;7(4):20552173211048756. Epub 2021 Nov 5. PMID: 34777854
Study Type : Human Study
Additional Links
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Pubmed Data : Neurol Sci. 2022 May 10. Epub 2022 May 10. PMID: 35536495
Study Type : Human Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Neuroprotective Agents
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Pubmed Data : Int J Environ Res Public Health. 2022 Aug 18 ;19(16). Epub 2022 Aug 18. PMID: 36011907
Study Type : Human Study
Additional Links
Substances : Melatonin, Tart Cherry
Diseases : Sleep Disorders
Therapeutic Actions : Exercise
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Pubmed Data : Iran J Child Neurol. 2024 ;18(3):57-63. Epub 2024 Jun 22. PMID: 38988849
Study Type : Human Study
Additional Links
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Diseases : Migraines
Pharmacological Actions : Prophylactic Agents
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Pubmed Data : Sleep Med. 2020 Oct 17 ;76:113-119. Epub 2020 Oct 17. PMID: 33157425
Study Type : Human Study
Additional Links
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Diseases : Insomnia
Pharmacological Actions : Hypnotics and Sedatives
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Study Type : Human Study
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Study Type : Human Study
Additional Links
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Pubmed Data : Neurosci Lett. 2008 Jun 13 ;438(1):76-9. Epub 2008 Apr 16. PMID: 18472329
Study Type : Human Study
Additional Links
Substances : Melatonin
Additional Keywords : Geomagnetic Activity
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Pubmed Data : J Pineal Res. 2022 Aug ;73(1):e12801. Epub 2022 May 13. PMID: 35436355
Study Type : Human Study
Additional Links
Substances : Melatonin
Diseases : Sleep Disorders
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Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2016 Nov 9. Epub 2016 Nov 9. PMID: 28151704
Study Type : Human Study
Additional Links
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Diseases : Breast Cancer
Additional Keywords : Risk Factors, Risk Reduction
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Pubmed Data : Integr Cancer Ther. 2023 ;22:15347354231168624. PMID: 37139718
Study Type : Human Study
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Pharmacological Actions : Chemotherapeutic
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Pubmed Data : JGH Open. 2020 Aug ;4(4):749-756. Epub 2020 May 18. PMID: 32782966
Study Type : Human Study
Additional Links
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Pubmed Data : J Cancer. 2016 ;7(7):831-6. Epub 2016 Apr 27. PMID: 27162542
Study Type : Human Study
Additional Links
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Diseases : Ovarian Cancer
Additional Keywords : Risk Reduction
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Study Type : Human Study
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Pharmacological Actions : Secretagogue
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Pubmed Data : J Am Board Fam Med. 2022 ;35(4):695-707. PMID: 35896462
Study Type : Human Study
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Pubmed Data : J Pineal Res. 2021 Dec ;71(4):e12770. Epub 2021 Oct 9. PMID: 34582575
Study Type : Human Study
Additional Links
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Pharmacological Actions : Hypolipidemic, Insulin Sensitizers
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Study Type : Human Study
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Study Type : Human Study
Additional Links
Substances : Melatonin, Tryptophan
Diseases : Pancreatitis
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Pubmed Data : Int J Dermatol. 2020 Mar 5. Epub 2020 Mar 5. PMID: 32141063
Study Type : Human Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Antioxidants
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Study Type : Human Study
Additional Links
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Pharmacological Actions : Anxiolytic
Additional Keywords : Plant Extracts
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Study Type : Human Study
Additional Links
Substances : Melatonin, Vitamin E
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Study Type : Human Study
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Study Type : Human Study
Additional Links
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Pharmacological Actions : Analgesics
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Study Type : Human Study
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Diseases : Jet Lag
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Study Type : Human Study
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Diseases : Nocturia
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Pubmed Data : J Clin Exp Dent. 2015 Dec ;7(5):e628-e633. Epub 2015 Dec 1. PMID: 26644840
Study Type : Human Study
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Study Type : Human Study
Additional Links
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Diseases : Epilepsy
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Study Type : Human Study
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Pharmacological Actions : Prophylactic Agents
Additional Keywords : Natural Substances Versus Drugs
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Study Type : Human Study
Additional Links
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Study Type : Human Study
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Diseases : Scoliosis
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Pubmed Data : J Physiol Pharmacol. 2016 Apr ;67(2):235-42. PMID: 27226183
Study Type : Human Study
Additional Links
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Pharmacological Actions : Antioxidants
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Pubmed Data : Anticancer Res. 2003 Mar-Apr;23(2C):1951-4. PMID: 12820485
Study Type : Human Study
Additional Links
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Study Type : Human Study
Additional Links
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Additional Keywords : Drug: Omeprazole
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Study Type : Human Study
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Diseases : Prostate Cancer
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Pubmed Data : Oncotarget. 2020 Oct 13 ;11(41):3723-3729. Epub 2020 Oct 13. PMID: 33110479
Study Type : Human Study
Additional Links
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Diseases : Prostate Cancer
Pharmacological Actions : Chemotherapeutic
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Study Type : Human Study
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Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
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Pubmed Data : Res Q Exerc Sport. 2023 Sep ;94(3):869-879. Epub 2022 May 16. PMID: 35575746
Study Type : Human Study
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Diseases : Liver Damage
Therapeutic Actions : Exercise
Pharmacological Actions : Hepatoprotective
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Pubmed Data : Heliyon. 2024 Apr 30 ;10(8):e29291. Epub 2024 Apr 9. PMID: 38644851
Study Type : Human Study
Additional Links
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Pharmacological Actions : Antiproliferative
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Study Type : Human Study
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Pharmacological Actions : Analgesics
Problem Substances : Hypnotic Drugs
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Pubmed Data : Pain Ther. 2020 Dec ;9(2):741-750. Epub 2020 Oct 16. PMID: 33067764
Study Type : Human Study
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Diseases : Headache
Pharmacological Actions : Prophylactic Agents
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Pubmed Data : Ann Otol Rhinol Laryngol. 2011 Jul ;120(7):433-40. PMID: 21859051
Study Type : Human Study
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Diseases : Tinnitus
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Pubmed Data : Mov Disord. 2016 Mar 12. Epub 2016 Mar 12. PMID: 26971528
Study Type : Human Study
Additional Links
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Additional Keywords : Risk Factors
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Study Type : Human Study
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Diseases : Tinnitus
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Study Type : Human Study
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Diseases : Tinnitus
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Study Type : Human Study
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Study Type : Human Study
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Study Type : Human Study
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Study Type : Human Study
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Pharmacological Actions : Chemotherapeutic
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Study Type : Human Study
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Therapeutic Actions : Exercise
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
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Pubmed Data : Inflammopharmacology. 2023 Feb ;31(1):265-274. Epub 2022 Nov 19. PMID: 36401728
Study Type : Human Study
Additional Links
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Study Type : Human Study
Additional Links
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Diseases : Autism
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Study Type : Human Study
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Diseases : Insomnia
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Study Type : Human Study
Additional Links
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Therapeutic Actions : Placebo Effect
Pharmacological Actions : Antidepressive Agents
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Study Type : Human Study
Additional Links
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Pubmed Data : Clin Cardiol. 2022 Apr ;45(4):417-426. Epub 2022 Feb 16. PMID: 35170783
Study Type : Human Study
Additional Links
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Diseases : Heart Failure
Pharmacological Actions : Cardioprotective
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Study Type : Human Study
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Diseases : Hemodialysis
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Pubmed Data : Clin Cardiol. 2021 Sep ;44(9):1263-1271. Epub 2021 Jun 28. PMID: 34184295
Study Type : Human Study
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Diseases : Heart Failure
Pharmacological Actions : Cardioprotective
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Pubmed Data : BMC Womens Health. 2020 Nov 26 ;20(1):262. Epub 2020 Nov 26. PMID: 33243209
Study Type : Human Study
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Pharmacological Actions : Gastrointestinal Agents
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Study Type : Human Study
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Diseases : Stroke: Ischemic
Pharmacological Actions : Neuroprotective Agents
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Study Type : Human Study
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Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents
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Study Type : Human Study
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Diseases : Nocturia
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Study Type : Human Study
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Diseases : Insomnia
Problem Substances : Trazodone
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Pubmed Data : J Neurol Neurosurg Psychiatry. 2016 May 10. Epub 2016 May 10. PMID: 27165014
Study Type : Human Study
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Pharmacological Actions : Prophylactic Agents
Problem Substances : Antidepressants
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Pubmed Data : Pharmazie. 2005 Sep;60(9):696-700. PMID: 16222871
Study Type : Human Study
Additional Links
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Pharmacological Actions : Antioxidants
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Study Type : Human Study
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Diseases : Sleep Disorders
Problem Substances : Cell Phone Exposure
Adverse Pharmacological Actions : Melatonin Interference
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Pubmed Data : J Pineal Res. 2015 Jun 3. Epub 2015 Jun 3. PMID: 26036434
Study Type : Human Study
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Pharmacological Actions : Osteogenic
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Study Type : Human Study
Additional Links
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Additional Keywords : Light Pollution
Anti Therapeutic Actions : Blue Light (400−495 nm)
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Study Type : Human Study
Additional Links
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Additional Keywords : Risk Reduction
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Pubmed Data : Isr Med Assoc J. 2016 Mar-Apr;18(3-4):188-92. PMID: 27228641
Study Type : Human Study
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Additional Keywords : Risk Reduction
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Study Type : Human Study
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Pubmed Data : EPMA J. 2011 Dec ;2(4):351-6. Epub 2011 Dec 23. PMID: 23199173
Study Type : Human Study
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Diseases : Breast Cancer
Anti Therapeutic Actions : Shift Work
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Study Type : Human Study
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Pharmacological Actions : Sedative effects
Additional Keywords : Natural Substances Versus Drugs
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Study Type : Human Study
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Pharmacological Actions : Antioxidants
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Pubmed Data : Gynecol Obstet Fertil. 2013 Feb ;41(2):105-9. Epub 2013 Feb 6. PMID: 23395427
Study Type : Human Study
Additional Links
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Diseases : Breast Cancer
Anti Therapeutic Actions : Sleep Deprivation
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Study Type : Human Study
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Study Type : Human Study
Additional Links
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Pubmed Data : Complement Med Res. 2022 Feb 25. Epub 2022 Feb 25. PMID: 35220312
Study Type : Human Study
Additional Links
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Diseases : Pneumonia, Sepsis
Pharmacological Actions : Anti-Inflammatory Agents
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Pubmed Data : Oral Dis. 2019 Dec 23. Epub 2019 Dec 23. PMID: 31869853
Study Type : Human Study
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Diseases : Oral Mucositis
Pharmacological Actions : Radioprotective
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Study Type : Human Study
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Therapeutic Actions : Exercise: Resistance Training
Pharmacological Actions : Antioxidants
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Study Type : Human Study
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Diseases : Cataract
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Study Type : Human Study
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Pharmacological Actions : Cardioprotective
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Study Type : Human Study
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Pubmed Data : Integr Cancer Ther. 2024 ;23:15347354241237520. PMID: 38622853
Study Type : Human Study
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Diseases : Breast Cancer
Pharmacological Actions : Chemotherapeutic
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Pubmed Data : BMC Gastroenterol. 2023 Apr 25 ;23(1):135. Epub 2023 Apr 25. PMID: 37098505
Study Type : Human Study
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Pharmacological Actions : Gastrointestinal Agents
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Study Type : Human Study
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Pharmacological Actions : Analgesics
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Pubmed Data : Pediatr Blood Cancer. 2022 Jan ;69(1):e29393. Epub 2021 Oct 21. PMID: 34674368
Study Type : Human Study
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Diseases : Cancers: All
Pharmacological Actions : Neuroprotective Agents
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Study Type : Human Study
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Pharmacological Actions : Renoprotective
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Study Type : Human Study
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Pharmacological Actions : Radioprotective
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Study Type : Human Study
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Pharmacological Actions : Hypnotics and Sedatives
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Pubmed Data : J Clin Endocrinol Metab. 2015 Jun 8:jc20151859. Epub 2015 Jun 8. PMID: 26052727
Study Type : Human Study
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Study Type : Human Study
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Study Type : Human Study
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Pubmed Data : Funct Neurol. 2016 Mar 8:1-5. Epub 2016 Mar 8. PMID: 26954506
Study Type : Human Study
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Diseases : Headache
Pharmacological Actions : Prophylactic Agents
Additional Keywords : Risk Reduction
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Pubmed Data : Complement Ther Med. 2019 Aug ;45:104-108. Epub 2019 May 25. PMID: 31331545
Study Type : Human Study
Additional Links
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Additional Keywords : Plant Extracts
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Pubmed Data : Ann Thorac Cardiovasc Surg. 2015 May 25. Epub 2015 May 25. PMID: 26004111
Study Type : Human Study
Additional Links
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Additional Keywords : Significant Treatment Outcome
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Pubmed Data : Clin Endocrinol (Oxf). 2015 Sep 9. Epub 2015 Sep 9. PMID: 26352863
Study Type : Human Study
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Pharmacological Actions : Adiponectin upregulation
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Study Type : Animal Study, Human Study
Additional Links
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Pharmacological Actions : Hypoglycemic Agents
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Study Type : Human Study
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Study Type : Human Study
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Pharmacological Actions : Secretagogue
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Study Type : Animal Study, Human In Vitro
Additional Links
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Diseases : Liver Fibrosis
Pharmacological Actions : Anti-Fibrotic, Antioxidants, Hepatoprotective
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Pubmed Data : Radiat Environ Biophys. 2010 Nov ;49(4):731-41. Epub 2010 Jun 26. PMID: 20582429
Study Type : Human In Vitro
Additional Links
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Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
Adverse Pharmacological Actions : Oxidant
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Pubmed Data : Stem Cell Res Ther. 2019 10 17 ;10(1):306. Epub 2019 Oct 17. PMID: 31623678
Study Type : Human In Vitro
Additional Links
Pharmacological Actions : Antioxidant, Regenerative
[+]
Pubmed Data : Int J Radiat Biol. 2013 Nov ;89(11):993-1001. Epub 2013 Sep 3. PMID: 23952262
Study Type : Human In Vitro
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Physiol Biochem. 2016 Nov 7 ;39(6):2297-2307. Epub 2016 Aug 7. PMID: 27832629
Study Type : Human In Vitro
Additional Links
Substances : Melatonin
Diseases : Osteosarcoma
Pharmacological Actions : Antiproliferative
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2017 Feb 14 ;23(6):986-998. PMID: 28246472
Study Type : Human In Vitro
Additional Links
Substances : Melatonin
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, Cyclooxygenase 2 Inhibitors
[+]
Pubmed Data : Oncol Rep. 2017 Feb 14. Epub 2017 Feb 14. PMID: 28259965
Study Type : Human In Vitro
Additional Links
Substances : Melatonin
Diseases : Neuroblastoma
[+]
Pubmed Data : J Pineal Res. 2016 Jun 6. Epub 2016 Jun 6. PMID: 27265199
Study Type : Human In Vitro
[+]
Pubmed Data : J Pineal Res. 2015 Jul 16. Epub 2015 Jul 16. PMID: 26184924
Study Type : Human In Vitro
Additional Links
Substances : Melatonin
Diseases : Lung Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]
Pubmed Data : J Pineal Res. 2017 Feb 8. Epub 2017 Feb 8. PMID: 28178378
Study Type : Human In Vitro
Additional Links
Substances : Melatonin
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer
[+]
Pubmed Data : J Pineal Res. 2012 Sep ;53(2):154-65. Epub 2012 Feb 21. PMID: 22348531
Study Type : Human In Vitro
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Stem Cell Res Ther. 2019 Dec 21 ;10(1):408. Epub 2019 Dec 21. PMID: 31864412
Study Type : Human In Vitro
Additional Links
Substances : Melatonin
Pharmacological Actions : Regenerative
Additional Keywords : Bone Regeneration
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(3):e0150407. Epub 2016 Mar 2. PMID: 26934679
Study Type : Human In Vitro, In Vitro Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Anti-metastatic
Additional Keywords : Cancer Stem Cells
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2019 Dec ;44(6):2234-2244. Epub 2019 Sep 27. PMID: 31573052
Study Type : Human In Vitro
Additional Links
Substances : Melatonin
Pharmacological Actions : Regenerative
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : iScience. 2024 Apr 19 ;27(4):109511. Epub 2024 Mar 15. PMID: 38571759
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : MicroRNA-214
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2023 Nov ;28(5). Epub 2023 Sep 29. PMID: 37772370
Study Type : Animal Study, In Vitro Study
[+]
Pubmed Data : Free Radic Biol Med. 2023 Feb 1 ;195:13-22. Epub 2022 Dec 19. PMID: 36549428
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Antioxidants, Gastroprotective, Nrf2 activation
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Gastrotoxic
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Microbiol Res. 2023 Nov ;276:127480. Epub 2023 Aug 23. PMID: 37659335
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Hypoxia
Pharmacological Actions : Gastrointestinal Agents, Gastroprotective
[+]
Pubmed Data : Int Immunopharmacol. 2023 Nov ;124(Pt A):110801. Epub 2023 Aug 29. PMID: 37651854
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Melatonin
[+]
Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2024 Aug 17. Epub 2024 Aug 17. PMID: 39153053
Study Type : Animal Study, In Vitro Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2023 Mar 15 ;253:114674. Epub 2023 Feb 22. PMID: 36827899
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Hepatoprotective
Problem Substances : Sodium Fluoride
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Regen Res. 2021 Apr ;16(4):757-764. PMID: 33063739
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Neuroprotective Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pers Med. 2022 Feb 26 ;12(3). Epub 2022 Feb 26. PMID: 35330355
Study Type : Animal Study
Additional Links
Substances : Melatonin
[+]
Pubmed Data : Acta Histochem. 2020 Sep ;122(6):151596. Epub 2020 Jul 18. PMID: 32778234
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Osteoprotective
[+]
Pubmed Data : J Toxicol Environ Health A. 2012 ;75(18):1120-8. PMID: 22891885
Study Type : Animal Study
Additional Links
Substances : Melatonin, Testosterone
Adverse Pharmacological Actions : Endocrine Disruptor, Melatonin Interference
[+]
Pubmed Data : Toxicol Ind Health. 2004 Sep ;20(6-10):133-9. PMID: 15941010
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Antioxidants
[+]
Pubmed Data : Nutrition. 2019 Nov 27 ;72:110659. Epub 2019 Nov 27. PMID: 31986320
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Breast Cancer
[+]
Pubmed Data : Biofactors. 2017 Mar ;43(2):272-282. Epub 2016 Nov 1. PMID: 27801960
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Liver Cirrhosis
Pharmacological Actions : Anti-Fibrotic
Additional Keywords : Liver Regeneration
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Manag Res. 2021 ;13:8803-8808. Epub 2021 Nov 24. PMID: 34853535
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Gastric Cancer
Pharmacological Actions : Antiproliferative
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell J. 2016 ;18(1):46-51. Epub 2016 Apr 4. PMID: 27054118
Study Type : Animal Study
Additional Links
Substances : Melatonin, Vitamin C
Pharmacological Actions : Radioprotective
Additional Keywords : Natural Substance Synergy
Anti Therapeutic Actions : Radiotherapy
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Exp Pathol. 2005 Dec ;86(6):383-96. PMID: 16309544
Study Type : Animal Study
[+]
Pubmed Data : Behav Brain Res. 2015 Oct 13. Epub 2015 Oct 13. PMID: 26475510
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Cytoprotective, Neuroprotective Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2023 Aug 16 ;12(8). Epub 2023 Aug 16. PMID: 37627614
Study Type : Animal Study
Additional Links
Substances : Melatonin, Saffron
Diseases : Sleep Disorders
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2023 Oct 15 ;265:115536. Epub 2023 Oct 3. PMID: 37797427
Study Type : Animal Study
Additional Links
Substances : Melatonin
Problem Substances : Cadmium
[+]
Pubmed Data : Food Chem Toxicol. 2020 Oct 29 ;146:111829. Epub 2020 Oct 29. PMID: 33130240
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Pharm Res. 2022 Dec ;21(1):e133971. Epub 2023 Jan 24. PMID: 36896324
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Neuroprotective Agents
[+]
Pubmed Data : Medicina (Kaunas). 2023 Nov 17 ;59(11). Epub 2023 Nov 17. PMID: 38004075
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Neuroprotective Agents
[+]
Pubmed Data : Cartilage. 2021 12 ;13(2_suppl):1041S-1053S. Epub 2021 Nov 15. PMID: 34775836
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Apoptotic, Chondroprotective
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Life (Basel). 2022 Apr 12 ;12(4). Epub 2022 Apr 12. PMID: 35455066
Study Type : Animal Study
[+]
Pubmed Data : J Pineal Res. 2015 Jun 23. Epub 2015 Jun 23. PMID: 26103459
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Antioxidants
[+]
Pubmed Data : J Hazard Mater. 2023 Sep 15 ;458:131949. Epub 2023 Jun 29. PMID: 37392641
Study Type : Animal Study
Additional Links
Substances : Melatonin, Probiotics
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Gut-brain Axis
Problem Substances : Polystyrene nanoparticles
[+]
Pubmed Data : J Pineal Res. 2015 Oct 14. Epub 2015 Oct 14. PMID: 26465095
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Cardioprotective
[+]
Pubmed Data : Neuropharmacology. 2020 Nov 13 ;182:108401. Epub 2020 Nov 13. PMID: 33197466
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Optic Neuritis
Additional Keywords : Chronobiotic
[+]
Pubmed Data : Neuroimmunomodulation. 2017 Apr 19. Epub 2017 Apr 19. PMID: 28419991
Study Type : Animal Study
Additional Links
Substances : Melatonin, Resveratrol
Diseases : Dementia
Pharmacological Actions : Neuroprotective Agents
[+]
Pubmed Data : Drug Chem Toxicol. 2015 Jun 15:1-10. Epub 2015 Jun 15. PMID: 26072956
Study Type : Animal Study
Additional Links
Substances : Melatonin
[+]
Pubmed Data : Cent Nerv Syst Agents Med Chem. 2022 Apr 29. Epub 2022 Apr 29. PMID: 35507790
Study Type : Animal Study
Additional Links
Substances : Melatonin, Vitamin D
Diseases : Epilepsy
Pharmacological Actions : Anticonvulsants
[+]
Pubmed Data : Can J Physiol Pharmacol. 2020 Nov 17. Epub 2020 Nov 17. PMID: 33201734
Study Type : Animal Study
[+]
Pubmed Data : J Acupunct Meridian Stud. 2021 Oct 31 ;14(5):176-182. PMID: 35770586
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Sciatica
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Neuroprotective Agents, Regenerative
Additional Keywords : Nerve Regeneration
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ulus Travma Acil Cerrahi Derg. 2024 Jun ;30(6):397-405. PMID: 38863293
Study Type : Animal Study
Additional Links
Substances : Melatonin, Royal Jelly
Diseases : Wound Healing
Pharmacological Actions : Antioxidants
[+]
Pubmed Data : Toxicology. 2006 Aug 15;225(2-3):150-6. Epub 2006 May 26. PMID: 16806632
Study Type : Animal Study
Additional Links
Pharmacological Actions : Antioxidants
Additional Keywords : Stilbenes
[+]
Pubmed Data : Mol Neurobiol. 2017 Oct 30. Epub 2017 Oct 30. PMID: 29086246
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Obesity
Pharmacological Actions : Neuroprotective Agents
[+]
Pubmed Data : Comp Med. 2015 ;65(6):473-85. PMID: 26678364
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Prostate Cancer
Therapeutic Actions : Light Therapy
Pharmacological Actions : Antiproliferative
[+]
Pubmed Data : Endocr Metab Immune Disord Drug Targets. 2019 Oct 9. Epub 2019 Oct 9. PMID: 32138638
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Antioxidants
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 Dec 5 ;9(12). Epub 2017 Dec 5. PMID: 29206172
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Obesity, Prediabetes
Pharmacological Actions : Cardioprotective
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Med. 2022 Mar 30 ;11(7). Epub 2022 Mar 30. PMID: 35407517
Study Type : Animal Study
Additional Links
Substances : Melatonin
[+]
Pubmed Data : J Altern Complement Med. 2001 Jun;7(3):241-51. PMID: 11439845
Study Type : Animal Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2020 Nov ;131:110761. Epub 2020 Sep 19. PMID: 33152924
Study Type : Animal Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Rev Med Pharmacol Sci. 2024 Mar ;28(5):1920-1930. PMID: 38497875
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Hypothyroidism
[+]
Pubmed Data : Aust Endod J. 2024 Mar 21. Epub 2024 Mar 21. PMID: 38509787
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Periodontitis
Pharmacological Actions : Anti-Inflammatory Agents, Osteoprotective
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : F S Sci. 2024 Mar 12. Epub 2024 Mar 12. PMID: 38484797
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Antiproliferative
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Family Med Prim Care. 2022 Aug ;11(8):4500-4504. Epub 2022 Aug 30. PMID: 36352994
Study Type : Animal Study
Additional Links
Pharmacological Actions : Hepatoprotective
Problem Substances : Aluminum
[+]
Pubmed Data : J Pineal Res. 2023 Aug ;75(1):e12884. Epub 2023 May 22. PMID: 37177873
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Cardioprotective, Chemoprotective Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Turk J Med Sci. 2023 Aug ;53(4):894-901. Epub 2023 Aug 18. PMID: 38031940
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Neuroprotective Agents
[+]
Pubmed Data : J Diabetes Metab Disord. 2019 Dec ;18(2):543-549. Epub 2019 Dec 2. PMID: 31890680
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Antioxidants, Hypoglycemic Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 Sep 18 ;5:14206. Epub 2015 Sep 18. PMID: 26381579
Study Type : Animal Study
Additional Links
Substances : Melatonin
Anti Therapeutic Actions : Electromagnetic Field Harms
Adverse Pharmacological Actions : Melatonin Interference
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:3082438. Epub 2018 Feb 18. PMID: 29670679
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Antioxidants, Renoprotective
Problem Substances : Bisphenol A
[+]
Pubmed Data : Cell J. 2018 Apr ;20(1):108-112. Epub 2017 Dec 1. PMID: 29308626
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Infertility
Pharmacological Actions : Fertility Agents
[+]
Pubmed Data : Environ Pollut. 2020 Nov 9:116056. Epub 2020 Nov 9. PMID: 33199064
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Antioxidants
Problem Substances : Cadmium
[+]
Pubmed Data : Environ Toxicol Pharmacol. 2023 Jan ;97:104044. Epub 2022 Dec 22. PMID: 36566951
Study Type : Animal Study
Additional Links
Substances : Melatonin
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Metab (Lond). 2020 ;17:6. Epub 2020 Jan 14. PMID: 31956332
Study Type : Animal Study
Additional Links
Substances : Folic Acid , Melatonin
[+]
Pubmed Data : Mol Nutr Food Res. 2015 May ;59(5):865-78. Epub 2015 Mar 23. PMID: 25677201
Study Type : Animal Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Lasers Med Sci. 2024 ;15:e39. Epub 2024 Aug 11. PMID: 39193106
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Periodontitis
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Anti-Inflammatory Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mediators Inflamm. 2016 ;2016:9050828. Epub 2016 Feb 18. PMID: 26989334
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]
Pubmed Data : Biofactors. 2020 Nov 2:e1690. Epub 2020 Nov 2. PMID: 33135223
Study Type : Animal Study
Additional Links
Substances : Melatonin
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2021 Sep ;22(3):1014. Epub 2021 Jul 15. PMID: 34373700
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Liver Damage
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]
Pubmed Data : Food Funct. 2016 Mar ;7(3):1438-45. PMID: 26841704
Study Type : Animal Study
Additional Links
Substances : Beans: All , Melatonin
Pharmacological Actions : Antioxidants
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2015 ;16(14):6061-6. PMID: 26320496
Study Type : Animal Study
Additional Links
Substances : Lycopene, Melatonin
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Okajimas Folia Anat Jpn. 2002 May ;79(1):25-31. PMID: 12199535
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Radioprotective
Adverse Pharmacological Actions : Cytotoxic, Hepatotoxic
[+]
Pubmed Data : Environ Sci Pollut Res Int. 2021 Jan 5. Epub 2021 Jan 5. PMID: 33398767
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
Problem Substances : Bisphenol A
[+]
Pubmed Data : J Alzheimers Dis. 2015 Jul 9 ;47(1):103-16. PMID: 26402759
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Neuroprotective Agents
[+]
Pubmed Data : Psychopharmacology (Berl). 2017 Feb 28. Epub 2017 Feb 28. PMID: 28246896
Study Type : Animal Study
Additional Links
Substances : Melatonin
[+]
Pubmed Data : Cent European J Urol. 2016 ;69(2):225-30. Epub 2016 Jun 20. PMID: 27551563
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Anti-Apoptotic, Renoprotective
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2015;2015:703709. Epub 2015 Jun 21. PMID: 26185593
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Antioxidants, Chemopreventive
Additional Keywords : Risk Reduction
Problem Substances : Acrylamide
[+]
Pubmed Data : Food Chem Toxicol. 2023 Aug ;178:113867. Epub 2023 Jun 1. PMID: 37269891
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Fertility Agents: Male
Additional Keywords : Gene Expression Regulation
Problem Substances : Sodium Fluoride
[+]
Pubmed Data : J Pineal Res. 2016 Oct 1. Epub 2016 Aug 1. PMID: 27696512
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Liver Cancer
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
Additional Keywords : Risk Reduction
[+]
Pubmed Data : Ecotoxicol Environ Saf. 2019 May 30 ;173:131-141. Epub 2019 Feb 13. PMID: 30771656
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Nrf2 activation
Problem Substances : Aluminum Chloride
[+]
Pubmed Data : J Hazard Mater. 2023 Oct 15 ;460:132274. Epub 2023 Aug 19. PMID: 37643573
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Antioxidants
Problem Substances : Aluminum
[+]
Pubmed Data : Aging (Albany NY). 2020 Nov 26 ;12. Epub 2020 Nov 26. PMID: 33259334
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Cardioprotective
[+]
Pubmed Data : Front Biosci (Landmark Ed). 2024 Mar 8 ;29(3):95. PMID: 38538260
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Anti-Apoptotic, Antioxidants
Problem Substances : Bisphenol A
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Transl Psychiatry. 2024 Mar 27 ;14(1):166. Epub 2024 Mar 27. PMID: 38538614
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]
Pubmed Data : Free Radic Biol Med. 2023 Nov 1 ;208:555-570. Epub 2023 Sep 17. PMID: 37717795
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Neuroprotective Agents
[+]
Pubmed Data : Environ Pollut. 2024 Mar 22 ;348:123828. Epub 2024 Mar 22. PMID: 38522604
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Antioxidants
Problem Substances : Glyphosate
[+]
Pubmed Data : Reprod Biol. 2021 Dec 22 ;22(1):100594. Epub 2021 Dec 22. PMID: 34953312
Study Type : Animal Study
Additional Links
Substances : Melatonin
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2023 Sep 3 ;24(17). Epub 2023 Sep 3. PMID: 37686424
Study Type : Animal Study
Additional Links
Substances : Melatonin
Additional Keywords : Microplastic
Problem Substances : Polyethylene
Adverse Pharmacological Actions : Gastrotoxic
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aging Cell. 2017 Feb 3. Epub 2017 Feb 3. PMID: 28156052
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2024 Jan 5 ;25(2). Epub 2024 Jan 5. PMID: 38255808
Study Type : Animal Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS Pathog. 2023 May ;19(5):e1011406. Epub 2023 May 18. PMID: 37200384
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Influenza
Additional Keywords : Cytokine Storm
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Gastroenterol Res Pract. 2022 ;2022:6920577. Epub 2022 Mar 17. PMID: 35340691
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Anti-Inflammatory Agents
[+]
Pubmed Data : Front Cell Dev Biol. 2024 ;12:1338828. Epub 2024 Feb 19. PMID: 38440074
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Antioxidants
Problem Substances : Bisphenol A
[+]
Pubmed Data : CNS Neurol Disord Drug Targets. 2020 Oct 12. Epub 2020 Oct 12. PMID: 33045971
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Hypertension
Pharmacological Actions : Anti-Apoptotic
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2022 Apr ;23(4):248. Epub 2022 Jan 31. PMID: 35261620
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Anti-Anxiety Agents
[+]
Pubmed Data : Neuroreport. 2020 Nov 5. Epub 2020 Nov 5. PMID: 33165196
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]
Pubmed Data : Biol Trace Elem Res. 2019 Dec 11. Epub 2019 Dec 11. PMID: 31828722
Study Type : Animal Study