Mucuna pruriens (aka Velvet Beans)

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49 Diseases Researched for Mucuna pruriens (aka Velvet Beans)
NameACCKFocus
Parkinson's Disease2692Locked
Hyperglycemia223Locked
Hypertension313Locked
Infertility: Male510Locked
Chemically-Induced Liver Damage48Locked
Alcohol Toxicity 36Locked
Erectile Dysfunction36Locked
Kidney Damage: Chemically-Induced36Locked
Stress36Locked
Depression35Locked
Snake Bite: Venom Toxicity 35Locked
Aging24Locked
Obesity24Locked
Testicular Injury: Chemical/Metal Induced24Locked
Alzheimer's Disease23Locked
Brain Inflammation 23Locked
Neurodegenerative Diseases23Locked
Acetaminophen (Tylenol) Toxicity 12Locked
Anxiety12Locked
Arsenic Poisoning12Locked
Brain: Oxidative Stress12Locked
Cerebral Ischemia12Locked
Diabetes Mellitus: Type 1: Prevention12Locked
Diabetic Complications12Locked
Gastric Ulcer12Locked
High Fat Diet12Locked
High Fructose Diet12Locked
Inflammation22Locked
Ischemia12Locked
Kidney Damage: Drug-Induced12Locked
Lipid Peroxidation12Locked
Lipopolysaccharide-Induced Toxicity22Locked
Liver Cancer22Locked
Low Libido12Locked
Oxidative Stress22Locked
Seizures12Locked
Thrombus12Locked
Traumatic Brain Injury12Locked
Tuberculosis Drug Induced Toxicity 12Locked
Amyotrophic Lateral Sclerosis11Locked
Breast Cancer: Triple Negative 11Locked
Colorectal Cancer11Locked
DNA damage11Locked
Diabetes Mellitus: Type 211Locked
Hepatitis C11Locked
Hydrogen Peroxide Induced Toxicity11Locked
Hypotension11Locked
Pulmonary Hypertension11Locked
Skin Diseases11Locked
42 Pharmacological Actions Researched for Mucuna pruriens (aka Velvet Beans)
NameACCKFocus
Neuroprotective Agents2474Locked
Antioxidants1127Locked
Hypoglycemic Agents223Locked
Fertility Agents: Male612Locked
Anti-Inflammatory Agents711Locked
Hepatoprotective48Locked
Renoprotective48Locked
Antidepressive Agents47Locked
Interleukin-6 Downregulation46Locked
Antihypertensive Agents45Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor35Locked
Hypolipidemic24Locked
Immunomodulatory24Locked
Malondialdehyde Down-regulation24Locked
NF-kappaB Inhibitor34Locked
Superoxide Dismutase Up-regulation24Locked
Acetylcholinesterase Inhibitor12Locked
Angiotensin-Converting Enzyme Inhibitors22Locked
Anti-Anxiety Agents12Locked
Anti-Apoptotic12Locked
Anti-Ulcer Agents12Locked
Anti-thrombotic12Locked
Antiproliferative 22Locked
Aphrodisiac 12Locked
Apoptotic22Locked
Cardioprotective12Locked
Catalase Up-Regulation12Locked
Gastrointestinal Agents12Locked
Gastroprotective12Locked
Interleukin-1 beta downregulation12Locked
Interleukin-2 Downregulation12Locked
Nrf2 activation12Locked
Prophylactic Agents12Locked
Alpha-glucosidase inhibitor 11Locked
Anti-Platelet11Locked
Antiviral Agents11Locked
Cell cycle arrest11Locked
Chemopreventive11Locked
Cyclooxygenase 2 Inhibitors11Locked
Interleukin-8 downregulation11Locked
Wnt/β-catenin signaling pathway modulation11Locked
anti-inflammatory11Locked

View the Evidence:
74 Abstracts with Mucuna pruriens (aka Velvet Beans) Research

[+]

Mucuna pruriens extract demonstrates significant antidiabetic potential through glycemic regulation and organ tissue restoration.Apr 30, 2025

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Vet World. 2025 May ;18(5):1377-1388. Epub 2025 May 31. PMID: 40584130
Article Published Date : Apr 30, 2025
Study Type : Meta Analysis, Review
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Hyperglycemia
Pharmacological Actions : Hypoglycemic Agents
[+]

A naturally occuring L-Dopa rich plant extract of Mucuna pruriens was found to be an effective treatment for patients with Parkinson's disease.Sep 01, 1995

Pubmed Data : J Altern Complement Med. 1995 Fall;1(3):249-55. PMID: 9395621
Article Published Date : Sep 01, 1995
Study Type : Human Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
[+]

Comparative efficacy of Mucuna pruriens and conventional levodopa in Parkinson's disease.Mar 25, 2025

Pubmed Data : J Neural Transm (Vienna). 2025 Mar 26. Epub 2025 Mar 26. PMID: 40137945
Article Published Date : Mar 25, 2025
Study Type : Human Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Natural Substances Versus Drugs
[+]

L-dopa from M. pruriens seed extract with the prominent antioxidant activity is a promising option for elderly patients suffering from Parkinson's disease.May 16, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceutics. 2022 May 17 ;14(5). Epub 2022 May 17. PMID: 35631666
Article Published Date : May 16, 2022
Study Type : Human Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Mucuna pruriens could be a sustainable alternative to marketed levodopa for indigent individuals with Parkinson disease.Jul 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neurology. 2017 Aug 1 ;89(5):432-438. Epub 2017 Jul 5. PMID: 28679598
Article Published Date : Jul 31, 2017
Study Type : Human Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Hypertension
Additional Keywords : Natural Substances Versus Drugs, Phytotherapy
[+]

Mucuna pruriens is effective in treating the symptoms of Parkinson's disease, without the concomitant increase in dyskinesias that occurs with conventional L-dopa preparations.Dec 01, 2004

Pubmed Data : J Neurol Neurosurg Psychiatry. 2004 Dec;75(12):1672-7. PMID: 15548480
Article Published Date : Dec 01, 2004
Study Type : Human Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
[+]

Mucuna pruriens showed fast-acting and long-lasting effects in Parkinson's disease.Oct 14, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Intern Med. 2024 Oct 15 ;63(20):2773-2779. Epub 2024 Mar 11. PMID: 38462520
Article Published Date : Oct 14, 2024
Study Type : Human Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Recovery of motor function is associated with rescue of glutamate biomarkers in the striatum and motor cortex following treatment with Mucuna pruriens.Aug 31, 2023

Pubmed Data : Mol Cell Neurosci. 2023 Sep ;126:103883. Epub 2023 Jul 30. PMID: 37527694
Article Published Date : Aug 31, 2023
Study Type : Human Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

A hydroalcoholic extract of M. pruriens seeds have antidepressant action.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ayu. 2014 Jan ;35(1):90-7. PMID: 25364207
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]

Aging induced testicular damage: analyzing the ameliorative potential of Mucuna pruriens seed extract.May 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : 3 Biotech. 2023 Jun ;13(6):206. Epub 2023 May 22. PMID: 37229277
Article Published Date : May 31, 2023
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Aging, Infertility: Male
Pharmacological Actions : Fertility Agents: Male
[+]

Ameliorating effect of Mucuna pruriens seed extract on sodium arsenite-induced testicular toxicity and hepato-renal histopathology in rats.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Vet World. 2023 Jan ;16(1):82-93. Epub 2023 Jan 11. PMID: 36855363
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Fertility Agents: Male, Hepatoprotective, Renoprotective
Problem Substances : Arsenite
[+]

An ethanol extract of Mucuna pruriens produces a sustained increase in sexual activity in normal male rats. Apr 21, 2009

Pubmed Data : J Ethnopharmacol. 2009 Apr 21;122(3):497-501. Epub 2009 Jan 31. PMID: 19429319
Article Published Date : Apr 21, 2009
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Low Libido
Pharmacological Actions : Aphrodisiac
[+]

Antiulcer and antioxidant activity of a lectin from Mucuna pruriens seeds on ethanol- induced gastropathy.Dec 31, 2018

Pubmed Data : Curr Pharm Des. 2019 ;25(12):1430-1439. PMID: 31124421
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Alcohol Toxicity , Gastric Ulcer, Lipid Peroxidation
Pharmacological Actions : Anti-Ulcer Agents, Antioxidants, Gastroprotective
Additional Keywords : Lectins, Phytotherapy, Plant Extracts
[+]

Comparative evaluation of extract of Bacopa monnieri and Mucuna pruriens as neuroprotectant in MPTP model of Parkinson’s disease.Oct 31, 2016

Pubmed Data : Indian J Exp Biol. 2016 Nov ;54(11):758-66. PMID: 30179419
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Bacopa, Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Effect of Mucuna pruriens on brain NMDA receptor and tau protein gene expression in cerebral ischemic rats.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Physiol. 2023 ;14:1092032. Epub 2023 Feb 16. PMID: 36875022
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Cerebral Ischemia
Pharmacological Actions : Neuroprotective Agents
[+]

Effect of Mucuna pruriens seed extract on depression-like behavior derived from mild traumatic brain injury.Dec 31, 2023

Pubmed Data : Biomedicine (Taipei). 2024 ;14(3):23-30. Epub 2024 Sep 1. PMID: 39386181
Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Depression, Traumatic Brain Injury
Pharmacological Actions : Antidepressive Agents
[+]

Ethanolic extract of Mucuna pruriens leaves ameliorates carbon tetrachloride and rifampicin-induced hepatotoxicity and nephrotoxicity.Nov 16, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Med Ther. 2021 Nov 17 ;21(1):282. Epub 2021 Nov 17. PMID: 34789221
Article Published Date : Nov 16, 2021
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced
Pharmacological Actions : Hepatoprotective, Renoprotective
Additional Keywords : Plant Extracts
[+]

Hypolipidemic and antioxidant effects of vegetal milk produced with Mucuna pruriens L. seed in rats fed a high-fat diet.Oct 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Heliyon. 2022 Nov ;8(11):e11835. Epub 2022 Nov 23. PMID: 36458299
Article Published Date : Oct 31, 2022
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : High Fat Diet
Pharmacological Actions : Antioxidants, Hypolipidemic
[+]

Immunosuppressive effects of protein derivatives from Mucuna pruriens on a streptozotocin-induced type 1 diabetes murine model.Apr 30, 2019

Pubmed Data : J Food Biochem. 2019 May ;43(5):e12834. Epub 2019 Mar 14. PMID: 31353524
Article Published Date : Apr 30, 2019
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Diabetes Mellitus: Type 1: Prevention
Pharmacological Actions : Immunomodulatory
[+]

Levodopa-reduced Mucuna pruriens seed extract shows neuroprotective effects against Parkinson's.Aug 21, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Aug 22 ;10(9). Epub 2018 Aug 22. PMID: 30131460
Article Published Date : Aug 21, 2018
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

M. pruriens and M. pudica may be considered as promising antivenom agents for people living in a snake-bite prone environment.Dec 31, 2019

Pubmed Data : Recent Pat Biotechnol. 2020 ;14(2):134-144. PMID: 31652115
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Mimosa pudica, Mucuna pruriens (aka Velvet Beans)
Diseases : Snake Bite: Venom Toxicity
Additional Keywords : Plant Extracts
[+]

M. pruriens bioactive peptides have hypolipidemic effects and antithrombotic activity.Dec 31, 2015

Pubmed Data : Food Funct. 2016 Jan ;7(1):434-44. PMID: 26505152
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Thrombus
Pharmacological Actions : Anti-thrombotic, Hypolipidemic
[+]

M. pruriens extract showed significant protection against brain damage caused by ischemia.Sep 24, 2017

Pubmed Data : Neuroreport. 2017 Sep 25. Epub 2017 Sep 25. PMID: 28953092
Article Published Date : Sep 24, 2017
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Ischemia
Pharmacological Actions : Neuroprotective Agents
[+]

M. pruriens seed pre-treatment had cardio-protective actions against snake venom poisoning.Aug 31, 2014

Pubmed Data : Indian J Exp Biol. 2014 Sep ;52(9):849-59. PMID: 25241584
Article Published Date : Aug 31, 2014
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Snake Bite: Venom Toxicity
Pharmacological Actions : Cardioprotective, Prophylactic Agents
Additional Keywords : Gene Expression Regulation, Plant Extracts
[+]

Mucuna pruriens administration minimizes neuroinflammation and shows anxiolytic, antidepressant and slimming effects in obesity.Nov 25, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Nov 26 ;25(23). Epub 2020 Nov 26. PMID: 33256223
Article Published Date : Nov 25, 2020
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Anxiety, Brain Inflammation , Obesity
Pharmacological Actions : Anti-Anxiety Agents, Anti-Inflammatory Agents, Antidepressive Agents
Additional Keywords : Anti-Obesity Agents
[+]

Mucuna pruriens can be an effective treatment for neurodegenerative diseases.Dec 31, 2013

Pubmed Data : Neurochem Int. 2014 Jan ;65:1-13. Epub 2013 Dec 11. PMID: 24333323
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Mucuna pruriens could have therapeutic effects on free fatty acid metabolism and local inflammatory responses in the brains of rats fed with HFrD.Sep 10, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Princ Pract. 2017 Sep 11. Epub 2017 Sep 11. PMID: 28898884
Article Published Date : Sep 10, 2017
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : High Fructose Diet
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Mucuna pruriens demonstrates antiparkinsonian activity superior to L-Dopa in a rodent model of Parkinson's disease. Feb 01, 2009

Pubmed Data : Neurotox Res. 2009 Feb;15(2):111-22. Epub 2009 Feb 20. PMID: 19384573
Article Published Date : Feb 01, 2009
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Additional Keywords : Natural Substances Versus Drugs
[+]

Mucuna pruriens efficacy in treating Parkinson's disease may be independent of its levodopa content.Feb 01, 2004

Pubmed Data : Phytother Res. 2004 Feb;18(2):97-101. PMID: 15022157
Article Published Date : Feb 01, 2004
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
[+]

Mucuna pruriens is superior to levodopa as an antiparkinson and neurorestorative agent.Sep 01, 2004

Pubmed Data : Phytother Res. 2004 Sep;18(9):706-12. PMID: 15478206
Article Published Date : Sep 01, 2004
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
[+]

Mucuna pruriens protects or prevents the progression of Parkinson's disease.Jun 18, 2017

Pubmed Data : J Chem Neuroanat. 2017 Jun 19 ;85:27-35. Epub 2017 Jun 19. PMID: 28642128
Article Published Date : Jun 18, 2017
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-1 beta downregulation, Interleukin-2 Downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Mucuna pruriens protein hydrolysate could be used as a functional ingredient to prevent blood pressure increase.Dec 31, 2016

Pubmed Data : J Med Food. 2017 Jan ;20(1):37-45. Epub 2016 Nov 28. PMID: 27893308
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents
Additional Keywords : Plant Extracts
[+]

Mucuna pruriens reduces inducible nitric oxide synthase expression in Parkinsonian mice model.Feb 28, 2017

Pubmed Data : J Chem Neuroanat. 2017 Mar ;80:1-10. Epub 2016 Dec 2. PMID: 27919828
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Mucuna pruriens seed aqueous extract improved neuroprotective and acetylcholinesterase inhibitory effects compared with synthetic L-dopa.May 12, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2022 May 13 ;27(10). Epub 2022 May 13. PMID: 35630617
Article Published Date : May 12, 2022
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Alzheimer's Disease, Parkinson's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Mucuna pruriens seed extract treatment significantly reduced the Paraquat induced neurotoxicity.May 31, 2013

Pubmed Data : Neurochem Int. 2013 Jun ;62(8):1039-47. Epub 2013 Apr 3. PMID: 23562769
Article Published Date : May 31, 2013
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Brain: Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Malondialdehyde Down-regulation, Neuroprotective Agents
Additional Keywords : Plant Extracts
Problem Substances : Paraquat
[+]

Mucuna pruriens seed protects the hippocampal neurons and abrogates seizure indices in chemically-convulsed mice.Aug 31, 2022

Pubmed Data : J Chem Neuroanat. 2022 Sep ;123:102115. Epub 2022 May 31. PMID: 35662582
Article Published Date : Aug 31, 2022
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Seizures
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
Additional Keywords : Plant Extracts
[+]

Mucuna pruriens seed repeals the hypothalamic-pituitary-testicular axis disruption following carbamazepine treatment.Jun 29, 2023

Pubmed Data : Niger J Physiol Sci. 2023 Jun 30 ;38(1):113-119. Epub 2023 Jun 30. PMID: 38243374
Article Published Date : Jun 29, 2023
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Testicular Injury: Chemical/Metal Induced
Problem Substances : Carbamazepine
[+]

Mucuna pruriens treatment shows anti-obesity and intestinal health effects in obese rats.Jul 20, 2021

Pubmed Data : Food Funct. 2021 Jul 21 ;12(14):6479-6489. Epub 2021 Jun 2. PMID: 34076654
Article Published Date : Jul 20, 2021
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Obesity
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Anti-Obesity Agents
[+]

n-Propanol extract of boiled and fermented koro benguk (Mucuna pruriens seed) shows a neuroprotective effect.Aug 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Vet World. 2018 Sep ;11(9):1250-1254. Epub 2018 Sep 12. PMID: 30410229
Article Published Date : Aug 31, 2018
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Nephro-protective effect of Mucuna pruriens, Moringa oleifera, and Milk thistle extracts against APAP-induced acute kidney injury.Jul 07, 2025

Pubmed Data : Kidney Blood Press Res. 2025 Jul 8:1-24. Epub 2025 Jul 8. PMID: 40628252
Article Published Date : Jul 07, 2025
Study Type : Animal Study
Additional Links
Substances : Milk Thistle, Moringa oleifera, Mucuna pruriens (aka Velvet Beans)
Diseases : Acetaminophen (Tylenol) Toxicity , Kidney Damage: Drug-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Catalase Up-Regulation, Interleukin-6 Downregulation, Renoprotective, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Acetaminophen
[+]

Prevention of seminal vesicle damage by Mucuna pruriens var. pruriens seed extract in chronic unpredictable mild stress mice.Nov 30, 2023

Pubmed Data : Pharm Biol. 2023 Dec ;61(1):89-99. PMID: 36565036
Article Published Date : Nov 30, 2023
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Infertility: Male, Stress
Pharmacological Actions : Anti-Apoptotic, Fertility Agents: Male
Additional Keywords : Plant Extracts
[+]

Protective effect of Mucuna pruriens against arsenic-induced liver and kidney dysfunction and neurobehavioral alterations.Jul 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Vet World. 2020 Aug ;13(8):1555-1566. Epub 2020 Aug 12. PMID: 33061227
Article Published Date : Jul 31, 2020
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Arsenic Poisoning, Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced
Pharmacological Actions : Hepatoprotective, Neuroprotective Agents, Renoprotective
[+]

Protective effects of Thai Mucuna pruriens (L.) DC. var. pruriens seeds on sexual behaviors and essential reproductive markers in chronic unpredictable mild stress.Jun 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Complement Med. 2022 Jul ;12(4):402-413. Epub 2021 Dec 15. PMID: 35747354
Article Published Date : Jun 30, 2022
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Infertility: Male, Stress
Pharmacological Actions : Fertility Agents: Male
[+]

Seed extract of Thai Mucuna pruriens (L.) DC. var. pruriens enhances sexual performance and improves male reproductive damages in ethanol-induced rats.Jun 27, 2022

Pubmed Data : J Ethnopharmacol. 2022 Jun 28 ;292:115219. Epub 2022 Mar 24. PMID: 35339625
Article Published Date : Jun 27, 2022
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Alcohol Toxicity , Infertility: Male
Pharmacological Actions : Antioxidants, Fertility Agents: Male
Additional Keywords : Plant Extracts
[+]

Seed extract of Thai Mucuna pruriens reduced male reproductive damage in rats induced by chronic stress.Nov 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2022 Dec ;60(1):374-383. PMID: 35180038
Article Published Date : Nov 30, 2022
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Infertility: Male, Stress
Pharmacological Actions : Fertility Agents: Male
Additional Keywords : Plant Extracts
[+]

Sexual stimulatory effects of Mucuna pruriens in rodents.Dec 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ayurveda Integr Med. 2025 ;16(3):101130. Epub 2025 Jun 9. PMID: 40494136
Article Published Date : Dec 31, 2024
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Erectile Dysfunction, Hyperglycemia
Pharmacological Actions : Hypoglycemic Agents
[+]

The hydroethanolic extract of Mucuna pruriens leaves possesses hepatoprotective activity.Mar 31, 2014

Pubmed Data : Chin J Nat Med. 2014 Apr ;12(4):273-83. PMID: 24863352
Article Published Date : Mar 31, 2014
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans), Silymarin
Diseases : Alcohol Toxicity , Chemically-Induced Liver Damage, Tuberculosis Drug Induced Toxicity
Pharmacological Actions : Antioxidants, Hepatoprotective, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
[+]

The polar extract of M. pruriens seed can be used for erectile dysfunction therapy.Feb 28, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Trop Med. 2017 Mar ;10(3):238-252. Epub 2017 Mar 7. PMID: 28442107
Article Published Date : Feb 28, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Diabetic Complications, Erectile Dysfunction
Additional Keywords : Plant Extracts
[+]

Therapeutic potential of Mucuna pruriens (Linn.) on ageing induced damage in dorsal nerve of the penis and its implication on erectile function.Nov 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aging Male. 2020 Dec ;23(5):313-326. Epub 2018 Feb 15. PMID: 29447059
Article Published Date : Nov 30, 2020
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Aging, Erectile Dysfunction
[+]

This study confirms in this translational model the validity of Mucuna pruriens as a valuable approach for PD treatment.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(10):e110802. Epub 2014 Oct 23. PMID: 25340511
Article Published Date : Dec 31, 2013
Study Type : Insect Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

A methanolic extract of Mucuna pruriens might be helpful in the treatment of oxidative stress related skin diseases.Feb 02, 2014

Pubmed Data : J Ethnopharmacol. 2014 Feb 3 ;151(2):873-81. Epub 2013 Dec 5. PMID: 24315849
Article Published Date : Feb 02, 2014
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Oxidative Stress, Skin Diseases
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

An isolated isoquinoline alkaloid from Mucuna pruriens seeds had antiproliferative effects against Huh-7 cells.Dec 31, 2015

Pubmed Data : Nat Prod Res. 2016 ;30(4):460-3. Epub 2015 Mar 16. PMID: 25774560
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative
[+]

Antineoplastic effects of Mucuna pruriens against human colorectal adenocarcinoma.Feb 29, 2024

Pubmed Data : Appl Biochem Biotechnol. 2024 Mar ;196(3):1350-1364. Epub 2023 Jul 3. PMID: 37395947
Article Published Date : Feb 29, 2024
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Colorectal Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Plant Extracts
[+]

Ayurveda can strengthen the therapeutic armamentarium of Parkinson's disease to improve clinical outcomes.Aug 16, 2016

Pubmed Data : J Ethnopharmacol. 2016 Aug 17. Epub 2016 Aug 17. PMID: 27544001
Article Published Date : Aug 16, 2016
Study Type : Review
Additional Links
Substances : Ashwagandha, Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Bioactive molecules of Mucuna pruriens compounds have potential therapeutic value in the treatment of pulmonary vascular disease.Dec 31, 2023

Pubmed Data : In Silico Pharmacol. 2024 ;12(2):110. Epub 2024 Nov 19. PMID: 39575208
Article Published Date : Dec 31, 2023
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Pulmonary Hypertension
Pharmacological Actions : Antihypertensive Agents, Wnt/β-catenin signaling pathway modulation
[+]

Could Mucuna pruriens be the answer to Parkinson's disease management in sub-Saharan Africa and other low-income countries worldwide? Mar 31, 2020

Pubmed Data : Parkinsonism Relat Disord. 2020 Apr ;73:3-7. Epub 2020 Mar 10. PMID: 32179240
Article Published Date : Mar 31, 2020
Study Type : Review
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Cytotoxic and cellular response of doped Nb-NTO nanoparticles functionalized with Mentha arvensis and Mucuna pruriens extracts on MDA-MB-231 breast cancer cells.Apr 02, 2025

Pubmed Data : Appl Biochem Biotechnol. 2025 Apr 3. Epub 2025 Apr 3. PMID: 40178700
Article Published Date : Apr 02, 2025
Study Type : In Vitro Study
Additional Links
Substances : Mint, Mucuna pruriens (aka Velvet Beans)
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : anti-inflammatory, Apoptotic, Interleukin-6 Downregulation, Interleukin-8 downregulation
Additional Keywords : Cancer Stem Cells
[+]

Isoflavanones, isoflavones, and pterocarpans of M. pruriens were found to be α-glucosidase inhibitors.Apr 30, 2014

Pubmed Data : Planta Med. 2014 May ;80(7):604-8. Epub 2014 Apr 29. PMID: 24782227
Article Published Date : Apr 30, 2014
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Alpha-glucosidase inhibitor
Additional Keywords : Plant Extracts
[+]

M. pruriens extracts have the potential for use as an anti-inflammatory material.Dec 11, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2022 Dec 12 ;27(24). Epub 2022 Dec 12. PMID: 36557931
Article Published Date : Dec 11, 2022
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor
[+]

M. pruriens peptides act as antihypertensives, antioxidants, and inhibitors for human platelet aggregation and cholesterol micellar solubility.Jan 31, 2016

Pubmed Data : J Med Food. 2016 Feb ;19(2):187-95. PMID: 26854846
Article Published Date : Jan 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Pharmacological Actions : Anti-Platelet, Antihypertensive Agents, Antioxidants
[+]

M. pruriens seed is a potential ACE inhibitor can be explored further as an effective antihypertensive agent.Dec 31, 2014

Pubmed Data : Pharm Biol. 2015 ;53(11):1614-20. Epub 2015 Apr 14. PMID: 25868619
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Hypertension
Pharmacological Actions : Angiotensin-Converting Enzyme Inhibitors
Additional Keywords : Plant Extracts
[+]

MP-4 contributes significantly to the snake venom neutralization activity of M. pruriens seeds.May 19, 2016

Pubmed Data : J Biol Chem. 2016 May 20 ;291(21):11373-84. Epub 2016 Mar 17. PMID: 26987900
Article Published Date : May 19, 2016
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Snake Bite: Venom Toxicity
[+]

Mucuna pruriens (L.) DC. seed extract inhibits lipopolysaccharide-induced inflammatory responses in BV2 microglial cells.Feb 28, 2021

Pubmed Data : J Ethnopharmacol. 2021 Mar 1 ;267:113518. Epub 2020 Oct 26. PMID: 33122120
Article Published Date : Feb 28, 2021
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
Additional Keywords : Plant Extracts
[+]

Mucuna pruriens has antioxidant and metal chelating activity independent of its levodopa content.Jan 01, 2008

Pubmed Data : Phytother Res. 2008 Jan;22(1):6-11. PMID: 18064727
Article Published Date : Jan 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
[+]

Mucuna pruriens in Parkinson’s and in some other diseases: recent advancement and future prospective.Nov 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : 3 Biotech. 2020 Dec ;10(12):522. Epub 2020 Nov 10. PMID: 33194526
Article Published Date : Nov 30, 2020
Study Type : Review
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Mucuna pruriens may become a sustainable therapeutic alternative for patients with Parkinson's disease.Jun 14, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neurol Sci. 2016 Jun 15 ;365:175-80. Epub 2016 Apr 16. PMID: 27206902
Article Published Date : Jun 14, 2016
Study Type : Plant Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
[+]

Mucuna pruriens to treat Parkinson's disease in low-income countries.Jun 30, 2024

Pubmed Data : Parkinsonism Relat Disord. 2024 Jul ;124:106983. Epub 2024 May 8. PMID: 38797572
Article Published Date : Jun 30, 2024
Study Type : Review
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Mucuna pruriens, a possible treatment for depressive disorders. Nov 15, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neurol Int. 2024 Nov 16 ;16(6):1509-1527. Epub 2024 Nov 16. PMID: 39585071
Article Published Date : Nov 15, 2024
Study Type : Review
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]

Neuroprotection by Mucuna pruriens in neurodegenerative diseases.Jun 30, 2022

Pubmed Data : Neurochem Res. 2022 Jul ;47(7):1816-1829. Epub 2022 Apr 5. PMID: 35380400
Article Published Date : Jun 30, 2022
Study Type : Review
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Peptides from Mucuna pruriens L., with protection and antioxidant in vitro effect on HeLa cell line.May 31, 2019

Pubmed Data : J Sci Food Agric. 2019 Jun ;99(8):4167-4173. Epub 2019 Mar 21. PMID: 30779130
Article Published Date : May 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Hydrogen Peroxide Induced Toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Phytochemicals in Parkinson's disease: a pathway to neuroprotection and personalized medicine.May 31, 2025

Pubmed Data : Cell Biochem Biophys. 2025 Jun ;83(2):1427-1443. Epub 2024 Nov 13. PMID: 39537915
Article Published Date : May 31, 2025
Study Type : Review
Additional Links
Substances : Ginkgo biloba, Mucuna pruriens (aka Velvet Beans), Turmeric
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Regulation of chronic neuroinflammation through dietary herbal products.Dec 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2025 ;12:1487786. Epub 2025 Apr 9. PMID: 40297338
Article Published Date : Dec 31, 2024
Study Type : Review
Additional Links
Substances : Amla Fruit, Bacopa, Black Pepper, Dates, Gotu Kola, Moringa oleifera, Mucuna pruriens (aka Velvet Beans), Pomegranate, Turmeric
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The study revealed the antihypertensive potential of Mucuna pruriens seed compounds via ACE inhibition.Jun 20, 2017

Pubmed Data : J Complement Integr Med. 2017 Jun 21. Epub 2017 Jun 21. PMID: 28640753
Article Published Date : Jun 20, 2017
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Hypotension
Pharmacological Actions : Angiotensin-Converting Enzyme Inhibitors, Antihypertensive Agents
[+]

Therapeutic peptides of Mucuna pruriens L.: Anti-genotoxic molecules against human hepatocellular carcinoma and hepatitis C virus.May 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2021 Jun ;9(6):2908-2914. Epub 2021 Mar 25. PMID: 34136158
Article Published Date : May 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : DNA damage, Hepatitis C, Liver Cancer
Pharmacological Actions : Antiviral Agents, Chemopreventive

Copyright: ztun1971 / 123RF Stock Photo

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Despite the devastating impact of Parkinson's disease on millions of lives, the FDA has failed to approve a single drug that can prevent the decline of health in affected patients. While pharmaceutical companies focus on patented chemicals, a wealth of research points to the untapped potential of natural compounds in the fight against this debilitating condition.

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