Mucuna pruriens (aka Velvet Beans)

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20 Diseases Researched for Mucuna pruriens (aka Velvet Beans)
NameACCKFocus
Parkinson's Disease1339Locked
Hypertension313Locked
Snake Bite: Venom Toxicity 23Locked
Alcohol Toxicity 12Locked
Brain: Oxidative Stress12Locked
Chemically-Induced Liver Damage12Locked
Depression12Locked
Diabetic Complications12Locked
Erectile Dysfunction12Locked
High Fructose Diet12Locked
Ischemia12Locked
Low Libido12Locked
Neurodegenerative Diseases12Locked
Thrombus12Locked
Tuberculosis Drug Induced Toxicity 12Locked
Diabetes Mellitus: Type 211Locked
Hypotension11Locked
Liver Cancer11Locked
Oxidative Stress11Locked
Skin Diseases11Locked
23 Pharmacological Actions Researched for Mucuna pruriens (aka Velvet Beans)
NameACCKFocus
Neuroprotective Agents815Locked
Antioxidants46Locked
Anti-Inflammatory Agents24Locked
Antihypertensive Agents34Locked
Malondialdehyde Down-regulation24Locked
Angiotensin-Converting Enzyme Inhibitors22Locked
Anti-thrombotic12Locked
Antidepressive Agents12Locked
Aphrodisiac 12Locked
Cardioprotective12Locked
Hepatoprotective12Locked
Hypolipidemic12Locked
Immunomodulatory12Locked
Interleukin-1 beta downregulation12Locked
Interleukin-2 Downregulation12Locked
Interleukin-6 Downregulation12Locked
NF-kappaB Inhibitor12Locked
Prophylactic Agents12Locked
Superoxide Dismutase Up-regulation12Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor12Locked
Alpha-glucosidase inhibitor 11Locked
Anti-Platelet11Locked
Antiproliferative 11Locked

View the Evidence:
30 Abstracts with Mucuna pruriens (aka Velvet Beans) Research

[+]

A naturally occuring L-Dopa rich plant extract of Mucuna pruriens was found to be an effective treatment for patients with Parkinson's disease.Sep 01, 1995

Pubmed Data : J Altern Complement Med. 1995 Fall;1(3):249-55. PMID: 9395621
Article Published Date : Sep 01, 1995
Study Type : Human Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
[+]

Mucuna pruriens could be a sustainable alternative to marketed levodopa for indigent individuals with Parkinson disease.Jul 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neurology. 2017 Aug 1 ;89(5):432-438. Epub 2017 Jul 5. PMID: 28679598
Article Published Date : Jul 31, 2017
Study Type : Human Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Hypertension
Additional Keywords : Natural Substances Versus Drugs, Phytotherapy
[+]

Mucuna pruriens is effective in treating the symptoms of Parkinson's disease, without the concomitant increase in dyskinesias that occurs with conventional L-dopa preparations.Dec 01, 2004

Pubmed Data : J Neurol Neurosurg Psychiatry. 2004 Dec;75(12):1672-7. PMID: 15548480
Article Published Date : Dec 01, 2004
Study Type : Human Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
[+]

A hydroalcoholic extract of M. pruriens seeds have antidepressant action.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ayu. 2014 Jan ;35(1):90-7. PMID: 25364207
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]

An ethanol extract of Mucuna pruriens produces a sustained increase in sexual activity in normal male rats. Apr 21, 2009

Pubmed Data : J Ethnopharmacol. 2009 Apr 21;122(3):497-501. Epub 2009 Jan 31. PMID: 19429319
Article Published Date : Apr 21, 2009
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Low Libido
Pharmacological Actions : Aphrodisiac
[+]

M. pruriens bioactive peptides have hypolipidemic effects and antithrombotic activity.Dec 31, 2015

Pubmed Data : Food Funct. 2016 Jan ;7(1):434-44. PMID: 26505152
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Thrombus
Pharmacological Actions : Anti-thrombotic, Hypolipidemic
[+]

M. pruriens extract showed significant protection against brain damage caused by ischemia.Sep 24, 2017

Pubmed Data : Neuroreport. 2017 Sep 25. Epub 2017 Sep 25. PMID: 28953092
Article Published Date : Sep 24, 2017
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Ischemia
Pharmacological Actions : Neuroprotective Agents
[+]

M. pruriens seed pre-treatment had cardio-protective actions against snake venom poisoning.Aug 31, 2014

Pubmed Data : Indian J Exp Biol. 2014 Sep ;52(9):849-59. PMID: 25241584
Article Published Date : Aug 31, 2014
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Snake Bite: Venom Toxicity
Pharmacological Actions : Cardioprotective, Prophylactic Agents
Additional Keywords : Gene Expression Regulation, Plant Extracts
[+]

Mucuna pruriens can be an effective treatment for neurodegenerative diseases.Dec 31, 2013

Pubmed Data : Neurochem Int. 2014 Jan ;65:1-13. Epub 2013 Dec 11. PMID: 24333323
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Mucuna pruriens could have therapeutic effects on free fatty acid metabolism and local inflammatory responses in the brains of rats fed with HFrD.Sep 10, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Princ Pract. 2017 Sep 11. Epub 2017 Sep 11. PMID: 28898884
Article Published Date : Sep 10, 2017
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : High Fructose Diet
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Mucuna pruriens demonstrates antiparkinsonian activity superior to L-Dopa in a rodent model of Parkinson's disease. Feb 01, 2009

Pubmed Data : Neurotox Res. 2009 Feb;15(2):111-22. Epub 2009 Feb 20. PMID: 19384573
Article Published Date : Feb 01, 2009
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Additional Keywords : Natural Substances Versus Drugs
[+]

Mucuna pruriens efficacy in treating Parkinson's disease may be independent of its levodopa content.Feb 01, 2004

Pubmed Data : Phytother Res. 2004 Feb;18(2):97-101. PMID: 15022157
Article Published Date : Feb 01, 2004
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
[+]

Mucuna pruriens is superior to levodopa as an antiparkinson and neurorestorative agent.Sep 01, 2004

Pubmed Data : Phytother Res. 2004 Sep;18(9):706-12. PMID: 15478206
Article Published Date : Sep 01, 2004
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
[+]

Mucuna pruriens protects or prevents the progression of Parkinson's disease.Jun 18, 2017

Pubmed Data : J Chem Neuroanat. 2017 Jun 19 ;85:27-35. Epub 2017 Jun 19. PMID: 28642128
Article Published Date : Jun 18, 2017
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-1 beta downregulation, Interleukin-2 Downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Mucuna pruriens protein hydrolysate could be used as a functional ingredient to prevent blood pressure increase.Dec 31, 2016

Pubmed Data : J Med Food. 2017 Jan ;20(1):37-45. Epub 2016 Nov 28. PMID: 27893308
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents
Additional Keywords : Plant Extracts
[+]

Mucuna pruriens reduces inducible nitric oxide synthase expression in Parkinsonian mice model.Feb 28, 2017

Pubmed Data : J Chem Neuroanat. 2017 Mar ;80:1-10. Epub 2016 Dec 2. PMID: 27919828
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Mucuna pruriens seed extract treatment significantly reduced the Paraquat induced neurotoxicity.May 31, 2013

Pubmed Data : Neurochem Int. 2013 Jun ;62(8):1039-47. Epub 2013 Apr 3. PMID: 23562769
Article Published Date : May 31, 2013
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Brain: Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Malondialdehyde Down-regulation, Neuroprotective Agents
Additional Keywords : Plant Extracts
Problem Substances : Paraquat
[+]

The hydroethanolic extract of Mucuna pruriens leaves possesses hepatoprotective activity.Mar 31, 2014

Pubmed Data : Chin J Nat Med. 2014 Apr ;12(4):273-83. PMID: 24863352
Article Published Date : Mar 31, 2014
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans), Silymarin
Diseases : Alcohol Toxicity , Chemically-Induced Liver Damage, Tuberculosis Drug Induced Toxicity
Pharmacological Actions : Antioxidants, Hepatoprotective, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
[+]

The polar extract of M. pruriens seed can be used for erectile dysfunction therapy.Feb 28, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Trop Med. 2017 Mar ;10(3):238-252. Epub 2017 Mar 7. PMID: 28442107
Article Published Date : Feb 28, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Diabetic Complications, Erectile Dysfunction
Additional Keywords : Plant Extracts
[+]

This study confirms in this translational model the validity of Mucuna pruriens as a valuable approach for PD treatment.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(10):e110802. Epub 2014 Oct 23. PMID: 25340511
Article Published Date : Dec 31, 2013
Study Type : Insect Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

A methanolic extract of Mucuna pruriens might be helpful in the treatment of oxidative stress related skin diseases.Feb 02, 2014

Pubmed Data : J Ethnopharmacol. 2014 Feb 3 ;151(2):873-81. Epub 2013 Dec 5. PMID: 24315849
Article Published Date : Feb 02, 2014
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Oxidative Stress, Skin Diseases
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

An isolated isoquinoline alkaloid from Mucuna pruriens seeds had antiproliferative effects against Huh-7 cells.Dec 31, 2015

Pubmed Data : Nat Prod Res. 2016 ;30(4):460-3. Epub 2015 Mar 16. PMID: 25774560
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative
[+]

Ayurveda can strengthen the therapeutic armamentarium of Parkinson's disease to improve clinical outcomes.Aug 16, 2016

Pubmed Data : J Ethnopharmacol. 2016 Aug 17. Epub 2016 Aug 17. PMID: 27544001
Article Published Date : Aug 16, 2016
Study Type : Review
Additional Links
Substances : Ashwagandha, Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Isoflavanones, isoflavones, and pterocarpans of M. pruriens were found to be α-glucosidase inhibitors.Apr 30, 2014

Pubmed Data : Planta Med. 2014 May ;80(7):604-8. Epub 2014 Apr 29. PMID: 24782227
Article Published Date : Apr 30, 2014
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Alpha-glucosidase inhibitor
Additional Keywords : Plant Extracts
[+]

M. pruriens peptides act as antihypertensives, antioxidants, and inhibitors for human platelet aggregation and cholesterol micellar solubility.Jan 31, 2016

Pubmed Data : J Med Food. 2016 Feb ;19(2):187-95. PMID: 26854846
Article Published Date : Jan 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Pharmacological Actions : Anti-Platelet, Antihypertensive Agents, Antioxidants
[+]

M. pruriens seed is a potential ACE inhibitor can be explored further as an effective antihypertensive agent.Dec 31, 2014

Pubmed Data : Pharm Biol. 2015 ;53(11):1614-20. Epub 2015 Apr 14. PMID: 25868619
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Hypertension
Pharmacological Actions : Angiotensin-Converting Enzyme Inhibitors
Additional Keywords : Plant Extracts
[+]

MP-4 contributes significantly to the snake venom neutralization activity of M. pruriens seeds.May 19, 2016

Pubmed Data : J Biol Chem. 2016 May 20 ;291(21):11373-84. Epub 2016 Mar 17. PMID: 26987900
Article Published Date : May 19, 2016
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Snake Bite: Venom Toxicity
[+]

Mucuna pruriens has antioxidant and metal chelating activity independent of its levodopa content.Jan 01, 2008

Pubmed Data : Phytother Res. 2008 Jan;22(1):6-11. PMID: 18064727
Article Published Date : Jan 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
[+]

Mucuna pruriens may become a sustainable therapeutic alternative for patients with Parkinson's disease.Jun 14, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neurol Sci. 2016 Jun 15 ;365:175-80. Epub 2016 Apr 16. PMID: 27206902
Article Published Date : Jun 14, 2016
Study Type : Plant Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Parkinson's Disease
[+]

The study revealed the antihypertensive potential of Mucuna pruriens seed compounds via ACE inhibition.Jun 20, 2017

Pubmed Data : J Complement Integr Med. 2017 Jun 21. Epub 2017 Jun 21. PMID: 28640753
Article Published Date : Jun 20, 2017
Study Type : In Vitro Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Hypotension
Pharmacological Actions : Angiotensin-Converting Enzyme Inhibitors, Antihypertensive Agents

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