NAC (N-acetyl-L-cysteine)

Name	AC	CK
Oxidative Stress	31	106
Chronic Obstructive Pulmonary Disease	9	73
Polycystic Ovary Syndrome	5	71
Inflammation	10	68
Coronavirus Infection	18	50
Liver Damage: Drug-Induced	12	47
Bronchitis: Chronic	2	40
C-Reactive Protein	3	40
Helicobacter Pylori Infection	4	33
Obsessive-Compulsive Disorder	6	33
Schizophrenia	4	32
Cystic Fibrosis	4	31
Aluminum Toxicity	5	29
Depression	6	28
Alzheimer's Disease	6	27
Liver Damage	5	26
Testicular Injury: Chemical/Metal Induced	11	21
Bipolar Disorder	2	20
Hearing Loss: Sudden	2	20
Myocardial Ischemia	1	20
Nail-Biting	2	20
Substance Abuse	1	20
Substance Withdrawal Syndrome	1	20
Aging	5	18
Chemically-Induced Liver Damage	10	18
Obesity	5	18
Air Pollution Linked Toxicity	3	17
Acetaminophen (Tylenol) Toxicity	9	16
Anxiety	4	16
Pulmonary Fibrosis	5	16
Tuberculosis Drug Induced Toxicity	4	16
Endometriosis	5	15
Infertility: Male	4	15
Radiation Induced Illness	4	15
Chemotherapy-Induced Toxicity: Cisplatin	8	14
DNA damage	4	14
Autism	2	13
Myocardial Infarction	3	13
Parkinson's Disease	3	13
Wound Healing	5	13
Breast Cancer	3	12
Diabetes Mellitus: Type 2	2	12
Diesel Exhaust Particle Toxicity	2	12
Endothelial Dysfunction	3	12
Sepsis	3	12
Silicosis	2	12
HIV Infections	2	11
Septic Shock	2	11
Sperm Quality: Low	2	11
Acute lymphoblastic leukemia (ALL)	1	10
Anxiety Disorders	1	10
Aphthous Ulcer	1	10
Autism Spectrum Disorders	1	10
Brain Damage	1	10
Breast: Mammographic Density	1	10
Cardiac Surgery	1	10
Chemotherapy-Induced Toxicity	1	10
Chronic Obstructive Lung Disease	1	10
Depression: Multiple Sclerosis	1	10
Depressive Disorder	1	10
Diabetic Neuropathy	1	10
Dysmenorrhea	1	10
Fibrinogen: Elevated	1	10
Gingivitis	1	10
Graves Disease	1	10
Head Injuries	1	10
Headache: Migraine	1	10
Hearing Loss: Noise-Induced	1	10
Hydrogen Peroxide Induced Toxicity	1	10
Hypertension	1	10
Infertility: Female	1	10
Intima Media Thickening	1	10
Klebsiella Infections	1	10
Lipopolysaccharide-Induced Toxicity	7	10
Lumbar Radiculopathy	1	10
Marijuana Addiction/Withdrawal	1	10
Muscle Soreness: Exercise-Induced	1	10
Organ Transplantation: Liver	1	10
Pesticide Toxicity	6	10
Pneumonia	1	10
Pneumonia: Ventilator-associated	1	10
Prostatitis: Chronic	1	10
Psychoses	1	10
Raynaud Disease	1	10
Sclerosis: Systemic	1	10
Serotonin Disorders	1	10
Smoking Cessation	1	10
Stomatitis: Aphthous	1	10
Suicidal Ideation	1	10
Thalassemia	1	10
Traumatic Brain Injury	1	10
Bisphenol Toxicity	5	9
Influenza A	7	9
Influenza	6	8
Cognitive Decline/Dysfunction	4	7
Glyphosate Toxicity	4	7
Pesticide-Induced Toxicity: Organophosphates	2	7
Brain: Oxidative Stress	3	6
Ischemia	3	6
Kidney Damage: Chemically-Induced	3	6
Kidney Damage: Drug-Induced	3	6
Lung Cancer	3	6
Brain Inflammation	3	5
Cancers: Multi-Drug Resistant	1	5
Diabetic Complications	3	5
Hepatitis	2	5
Multiple Myeloma	1	5
Aging: Immunosenecence	2	4
Alcohol Withdrawal	2	4
Cancers: All	3	4
Chemotherapy-Induced Toxicity: Cyclophosphamide	2	4
Cystitis	2	4
Dengue	2	4
Diabetic Nephropathy	2	4
Duchenne's Muscular Dystrophy	2	4
Fibrosis	2	4
Fluoride Toxicity	2	4
High Fat Diet	2	4
Lipid Peroxidation	2	4
Liver Cancer	3	4
Liver Failure: Acute	2	4
Lung Inflammation	2	4
Neurodegenerative Diseases	3	4
Osteoporosis	2	4
Pancreatic Cancer	3	4
Phthalate Toxicity	2	4
Radiation	2	4
Smoking	2	4
Spinal Cord Injuries	2	4
Cancers: Drug Resistant	2	3
Chemotherapy-Induced Kidney Damage	2	3
Chemotherapy-Induced Toxicity: Gentamicin	2	3
Diabetic Retinopathy	2	3
HIV Drug-Induced Toxicity	2	3
Hypoxia	2	3
Kidney Damage	2	3
Leukemia	2	3
Leukemia: Acute promyelocytic leukemia	2	3
Malaria	1	3
Mercury Poisoning	2	3
Mitochondrial Dysfunction	2	3
Postmenopausal Disorders	2	3
Sickle Cell Anemia	1	3
Alcohol Toxicity	1	2
Amebiasis	1	2
Asthma	1	2
Atherosclerosis	1	2
Binge Eating	1	2
Brain Injury: Traumatic	1	2
Burns	1	2
Cadmium Poisoning	1	2
Cardiac Arrest	1	2
Cardiac Hypertrophy	2	2
Cerebral Ischemia	1	2
Chemotherapy	1	2
Chemotherapy and Radiation Toxicity	1	2
Chemotherapy-Induced Toxicity: Doxorubicin	1	2
Chemotherapy-Induced Toxicity: Oxaliplatin	1	2
Chronic Pain	1	2
Cirrhosis	1	2
Cornea Damage	1	2
Coronavirus Disease	1	2
Coxsackievirus Infections	1	2
Cystitis: Interstitial	1	2
Diabetes: Hearing Loss	1	2
Diabetic Neuropathies	1	2
Diagnostic Imaging	1	2
Drug-Induced Toxicity: Valproic Acid (Depakote)	1	2
Dysbiosis	1	2
Dyskeratosis Congenita	1	2
Dyslipidemias	1	2
Eating Disorders	1	2
Escherichia coli Infections	2	2
Eye Damage	1	2
Fever	1	2
Formaldehyde Toxicity	1	2
Gastric Cancer	2	2
Gestational Diabetes	1	2
Glioblastoma	1	2
Hearing Loss	1	2
Heavy Metal Toxicity	1	2
High Sugar Diet	1	2
Hypertension: Pulmonary	1	2
Hyperthyroidism	1	2
Immune Disorders: Low Immune Function	1	2
Immune Dysregulation: TH1/TH2 imbalance	1	2
Kidney Diseases	1	2
Liver Cirrhosis	1	2
Liver Disease	1	2
Low Disorders: Low TH1	1	2
Lung Injury: Acute	1	2
Memory Disorders	1	2
Mobile Phone-Induced Oxidative Stress	1	2
Muscular Dystrophies	1	2
Mycobacterium Tuberculosis	1	2
Myeloproliferative Disorders	1	2
Myocarditis: Viral	1	2
Nicotine/Tobacco Toxicity	1	2
Nonalcoholic fatty liver disease (NAFLD)	1	2
Ocular Hypertension	1	2
Osteoarthritis	1	2
Peripheral Neuropathies	1	2
Post-Traumatic Stress Disorders (PTSD)	1	2
Postoperative Recovery	1	2
Prostate Cancer	1	2
Pulmonary Emphysema	1	2
Pulmonary Fibrosis: Bleomycin-Induced	1	2
Pyrethroid Insecticide Induced Toxicity	1	2
Radiation Induced Illness: Bone Marrow	1	2
Radiotherapy	1	2
Restenosis	1	2
Retinal Degeneration: Light-Induced	1	2
Rhinosinusitis	1	2
Rotator Cuff Problems	1	2
Sarcopenia	1	2
Smoking: Pulmonary	1	2
Staphylococcal Infections	1	2
Thrombosis	1	2
Thyroid Cancer	1	2
Advanced Glycation End products (AGE)	1	1
Aging Skin	1	1
Antibiotic Toxicity	1	1
Atrial Fibrillation	1	1
Avian Influenza	1	1
Bacterial Infections: Resistance/Biofilm Formation	1	1
Blood Storage Problems	1	1
Bone Diseases	1	1
Breast Cancer Stem Cells	1	1
Breast Cancer: Triple Negative	1	1
Cancer Metastasis	1	1
Cancers: Estrogen Responsive	1	1
Carcinoma: Non-Small-Cell Lung	1	1
Cardiac Arrhythmias	1	1
Colorectal Cancer	1	1
Common Cold	1	1
Down Syndrome	1	1
Estrogen Dominance	1	1
Head and Neck Cancer	1	1
Human T-Cell Lymphotrophic Virus type 1 associated disease	1	1
Infertility	1	1
Influenza B	1	1
Low Testosterone	1	1
Myocardial Infarction: Prevention	1	1
Polychlorinated biphenyl toxicity	1	1
Promyelocytic leukemia	1	1
Pseudomonas aeruginosa	1	1
Respiratory Tract Infections	1	1
Skin Diseases	1	1
Sperm Count: Low	1	1
Substance Use Disorders	1	1
Tuberculosis	1	1
Upper Respiratory Infections	1	1
Urinary Tract Infections	1	1
Virally-Induced Cytokine Storm	1	1
Interstitial Lung Diseases	1	0

Name	AC	CK
Antioxidants	130	400
Anti-Inflammatory Agents	57	206
Neuroprotective Agents	38	127
Hepatoprotective	37	118
Antidepressive Agents	9	68
Tumor Necrosis Factor (TNF) Alpha Inhibitor	15	68
Interleukin-6 Downregulation	9	51
Antiviral Agents	16	48
Cardioprotective	11	46
Hypoglycemic Agents	4	43
Immunomodulatory	11	42
Anti-Bacterial Agents	9	38
Chemoprotective Agents	16	37
Malondialdehyde Down-regulation	6	36
Antiproliferative	18	35
Apoptotic	14	33
Renoprotective	18	33
Analgesics	4	32
Cytoprotective	11	28
Anti-Fibrotic	10	23
Anticholesteremic Agents	2	23
Anti-Apoptotic	10	21
Superoxide Dismutase Up-regulation	5	17
Anti-Anxiety Agents	4	16
NF-kappaB Inhibitor	9	14
Interleukin-1 beta downregulation	7	13
Antineoplastic Agents	6	12
Fertility Agents: Male	2	12
Insulin Sensitizers	2	12
Radioprotective	6	12
Nrf2 activation	4	11
Anti-Ulcer Agents	1	10
Antimicrobial	1	10
Fertility Agents: Female	1	10
Mucolytic	1	10
Neurorestorative	1	10
Prophylactic Agents	1	10
Vascular Cell Adhesion Molecule-1 Inhibitor	1	10
Vasodilator Agents	1	10
Chemopreventive	5	8
Osteoprotective	4	7
Enzyme Inhibitors	4	5
Hypolipidemic	3	5
Protein Kinase Inhibitors	1	5
Chemotherapeutic	3	4
MicroRNA modulator	2	4
Angiogenesis Inhibitors	2	3
Anti-metastatic	2	3
Antimalarials	1	3
Matrix metalloproteinase-9 (MMP-9) inhibitor	2	3
Angiogenesis Inducing Agents	1	2
Anti-pyretic	1	2
Anticarcinogenic Agents	1	2
Anticonvulsants	1	2
Antimycobacterial	1	2
Antinoceceptive	1	2
Autophagy Up-regulation	1	2
Catalase Up-Regulation	1	2
Cell cycle arrest	1	2
Chemosensitizer	2	2
Gastrointestinal Agents	1	2
Genoprotective	1	2
Interleukin-8 downregulation	1	2
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	1	2
Matrix metalloproteinase-2 (MMP-2) inhibitor	2	2
Nootropic Agents	1	2
Pancreato Protective Agents	1	2
Prostaglandin PGE2 downregulation	1	2
Wound Healing Effects	1	2
Antimutagenic Agents	1	1
Antioxidant	1	1
Glutathione Upregulation	1	1
Heme oxygenase-1 up-regulation	1	1
Neocardiogenic	1	1
Quorum Sensing Inhibition	1	1
Transforming growth factor beta (TGF-β) inhibitor	1	1
Vascular Endothelial Growth Factor A Inhibitor	1	1

[+]

N-acetycysteine: A potential therapeutic agent in COVID-19 infection.Jul 23, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Med Hypotheses. 2020 Jul 24 ;144:110133. Epub 2020 Jul 24. PMID: 32758904

Article Published Date : Jul 23, 2020

Study Type : Commentary

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Coronavirus Infection

Pharmacological Actions : Antioxidants

[+]

N-acetyl cysteine and vitamin D supplementation in treatment resistant obsessive compulsive disorder patients.Jan 16, 2018

Click here to read the entire abstract

Pubmed Data : Curr Pharm Des. 2018 04 17. Epub 2018 Apr 17. PMID: 29663874

Article Published Date : Jan 16, 2018

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine), Vitamin D

Diseases : Obsessive-Compulsive Disorder

Pharmacological Actions : Neuroprotective Agents

[+]

N-acetyl cysteine has antiproliferative on pancreatic cancer cells. Dec 01, 2000

Click here to read the entire abstract

Pubmed Data : Hum Cell. 2000 Dec;13(4):213-20. PMID: 11329937

Article Published Date : Dec 01, 2000

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Pancreatic Cancer

Pharmacological Actions : Glutathione Upregulation

[+]

N-acetyl cysteine, selenium, and ascorbic acid rescue diabetic cardiac hypertrophy.Nov 29, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2021 Nov 30 ;26(23). Epub 2021 Nov 30. PMID: 34885867

Article Published Date : Nov 29, 2021

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine), Selenium, Vitamin C

Diseases : Cardiac Hypertrophy, Mitochondrial Dysfunction

Pharmacological Actions : Anti-Fibrotic, Antioxidants, Cardioprotective, Hypolipidemic

[+]

N-acetyl-L-cysteine attenuated influenza virus-induced NF-kappa B activation.Dec 31, 1997

Click here to read the entire abstract

Pubmed Data : Am J Physiol. 1998 Jan ;274(1 Pt 1):L134-42. PMID: 9458811

Article Published Date : Dec 31, 1997

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Influenza A

Pharmacological Actions : NF-kappaB Inhibitor, Superoxide Dismutase Up-regulation

[+]

N-acetyl-l-cystine (NAC) protects against H9N2 swine influenza virus-induced acute lung injury.Aug 31, 2014

Click here to read the entire abstract

Pubmed Data : Int Immunopharmacol. 2014 Sep ;22(1):1-8. Epub 2014 Jun 24. PMID: 24968347

Article Published Date : Aug 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Influenza

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

N-acetylcysteine (NAC) attenuates quorum sensing regulated phenotypes in Pseudomonas aeruginosa PAO1.Feb 28, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Heliyon. 2023 Mar ;9(3):e14152. Epub 2023 Feb 28. PMID: 36923901

Article Published Date : Feb 28, 2023

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Pseudomonas aeruginosa

Pharmacological Actions : Anti-Bacterial Agents, Quorum Sensing Inhibition

[+]

N-acetylcysteine alleviated paraquat-induced mitochondrial fragmentation and autophagy in primary murine neural progenitor cells.Jul 31, 2019

Click here to read the entire abstract

Pubmed Data : J Appl Toxicol. 2019 Aug 1. Epub 2019 Aug 1. PMID: 31368586

Article Published Date : Jul 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Neurodegenerative Diseases, Pesticide Toxicity

Pharmacological Actions : Neuroprotective Agents

Problem Substances : Paraquat

[+]

N-acetylcysteine ameliorates cisplatin-induced renal senescence and renal interstitial fibrosis.Dec 31, 2018

Click here to read the entire abstract

Pubmed Data : Free Radic Biol Med. 2019 01 ;130:512-527. Epub 2018 Nov 15. PMID: 30447351

Article Published Date : Dec 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Chemotherapy-Induced Kidney Damage, Chemotherapy-Induced Toxicity: Cisplatin, Oxidative Stress

Pharmacological Actions : Anti-Fibrotic, Antioxidants, Chemoprotective Agents, Renoprotective

[+]

N-acetylcysteine and coronavirus disease 2019: May it work as a beneficial preventive and adjuvant therapy?Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Res Med Sci. 2020 ;25:109. Epub 2020 Nov 26. PMID: 33824674

Article Published Date : Dec 31, 2019

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Coronavirus Infection

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Antiviral Agents

[+]

N-acetylcysteine as adjuvant therapy for COVID-19.Dec 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Inflamm Res. 2021 ;14:2993-3013. Epub 2021 Jul 6. PMID: 34262324

Article Published Date : Dec 31, 2020

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Coronavirus Infection

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

N-acetylcysteine attenuates cisplatin-induced acute kidney injury by inhibiting the C5a receptor.Dec 31, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Res Int. 2019 ;2019:4805853. Epub 2019 Apr 14. PMID: 31111056

Article Published Date : Dec 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Chemotherapy-Induced Toxicity: Cisplatin

Pharmacological Actions : Chemoprotective Agents, Renoprotective

[+]

N-acetylcysteine attenuates lipopolysaccharide-induced osteolysis by restoring bone remodelling balance. Feb 25, 2020

Click here to read the entire abstract

Pubmed Data : Inflammation. 2020 Feb 26. Epub 2020 Feb 26. PMID: 32103436

Article Published Date : Feb 25, 2020

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Bone Diseases, Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Antioxidants, Osteoprotective

[+]

N-acetylcysteine blocks SOS induction and mutagenesis produced by fluoroquinolones in Escherichia coli.Jul 31, 2019

Click here to read the entire abstract

Pubmed Data : J Antimicrob Chemother. 2019 Aug 1 ;74(8):2188-2196. PMID: 31102529

Article Published Date : Jul 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Antibiotic Toxicity , Bacterial Infections: Resistance/Biofilm Formation, Escherichia coli Infections

Pharmacological Actions : Antimutagenic Agents

Additional Keywords : Risk Reduction

Problem Substances : Fluoroquinolone Antibiotic

[+]

N-acetylcysteine can induce massive oxidative stress, resulting in cell death with apoptotic features in human leukemia cells.Nov 22, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2021 Nov 23 ;22(23). Epub 2021 Nov 23. PMID: 34884437

Article Published Date : Nov 22, 2021

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Leukemia: Acute promyelocytic leukemia

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

N-Acetylcysteine could be used in the management of bacterial spot of tomato caused by copper-resistant Xanthomonas perforans.Nov 10, 2020

Click here to read the entire abstract

Pubmed Data : Plant Dis. 2020 Nov 11:PDIS05200928RE. Epub 2020 Nov 11. PMID: 33175655

Article Published Date : Nov 10, 2020

Study Type : Plant Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine), Tomato

Additional Keywords : Plant Disease

[+]

N-acetylcysteine for non-acetaminophen induced acute liver failure.Feb 06, 2022

Click here to read the entire abstract

Pubmed Data : Saudi J Gastroenterol. 2022 Feb 7. Epub 2022 Feb 7. PMID: 35142656

Article Published Date : Feb 06, 2022

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Liver Damage, Liver Failure: Acute

Pharmacological Actions : Hepatoprotective

[+]

N-acetylcysteine for obsessive-compulsive and related disorders in children and adolescents.Nov 15, 2022

Click here to read the entire abstract

Pubmed Data : Ann Pharmacother. 2022 Nov 16:10600280221138092. Epub 2022 Nov 16. PMID: 36384314

Article Published Date : Nov 15, 2022

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Obsessive-Compulsive Disorder

[+]

N-acetylcysteine for the management of non-acetaminophen drug-induced liver injury.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2022 ;13:876868. Epub 2022 May 17. PMID: 35656297

Article Published Date : Dec 31, 2021

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Liver Damage: Drug-Induced

Pharmacological Actions : Hepatoprotective

[+]

N-acetylcysteine improves the inhibitory effect of quercetin-rich onion extract on HT-29 and HCT-116 colorectal cancer migration and invasion.Dec 31, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Med Sci. 2023 ;20(9):1123-1134. Epub 2023 Jul 24. PMID: 37575276

Article Published Date : Dec 31, 2022

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine), Onion, Quercetin

Diseases : Colorectal Cancer

Pharmacological Actions : Antineoplastic Agents, Antioxidants, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor

[+]

N-acetylcysteine in substance use disorder: a lesson from preclinical and clinical researchJun 05, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Pharmacol Rep. 2021 Jun 6. Epub 2021 Jun 6. PMID: 34091880

Article Published Date : Jun 05, 2021

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Substance Use Disorders

[+]

N-acetylcysteine inhalation improves the quality of life of patients with head and neck cancers who are receiving radiation therapy.Aug 13, 2020

Click here to read the entire abstract

Pubmed Data : J Cancer Res Clin Oncol. 2020 Aug 14. Epub 2020 Aug 14. PMID: 32803294

Article Published Date : Aug 13, 2020

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Head and Neck Cancer

Pharmacological Actions : Chemotherapeutic

[+]

N-acetylcysteine is recommended for all patients with acetaminophen-induced acute liver failure and it reduces mortality. Dec 31, 2017

Click here to read the entire abstract

Pubmed Data : Clin Liver Dis. 2018 05 ;22(2):325-346. Epub 2018 Feb 9. PMID: 29605069

Article Published Date : Dec 31, 2017

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Acetaminophen (Tylenol) Toxicity , Chemically-Induced Liver Damage

Pharmacological Actions : Hepatoprotective

Problem Substances : Acetaminophen, Paracetamol

[+]

N-Acetylcysteine prevents amyloid-β secretion in neurons derived from human pluripotent stem cells with trisomy 21.Aug 29, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2021 Aug 30 ;11(1):17377. Epub 2021 Aug 30. PMID: 34462463

Article Published Date : Aug 29, 2021

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Alzheimer's Disease, Down Syndrome

Pharmacological Actions : Antioxidants, Neuroprotective Agents

[+]

N-acetylcysteine promotes oral absorption of curcumin.Aug 04, 2020

Click here to read the entire abstract

Pubmed Data : Eur J Pharm Sci. 2020 Aug 5 ;154:105506. Epub 2020 Aug 5. PMID: 32763460

Article Published Date : Aug 04, 2020

Study Type : In Vitro Study

Additional Links

Substances : Curcumin, NAC (N-acetyl-L-cysteine)

Additional Keywords : Increased Bioavailability, Turmeric Absorption

[+]

N-Acetylcysteine protects against cobalt chloride-induced endothelial dysfunction by enhancing glucose-6-phosphate dehydrogenase activity.Jun 03, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : FEBS Open Bio. 2022 Jun 4. Epub 2022 Jun 4. PMID: 35666067

Article Published Date : Jun 03, 2022

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Endothelial Dysfunction

Pharmacological Actions : Cytoprotective

Problem Substances : Cobalt

[+]

N-acetylcysteine protects bladder epithelial cells from bacterial invasion and displays antibiofilm activity against urinary tract bacterial pathogens. Jul 22, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Antibiotics (Basel). 2021 Jul 23 ;10(8). Epub 2021 Jul 23. PMID: 34438950

Article Published Date : Jul 22, 2021

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Urinary Tract Infections

Pharmacological Actions : Anti-Bacterial Agents

Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation

[+]

N-acetylcysteine protects hepatocytes from hypoxia-related cell injuryNov 30, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Clin Exp Hepatol. 2018 Dec ;4(4):260-266. Epub 2018 Dec 3. PMID: 30603674

Article Published Date : Nov 30, 2018

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Hypoxia

Pharmacological Actions : Anti-Apoptotic, Cytoprotective

[+]

N-acetylcysteine provides cytoprotection in murine oligodendrocytes through heme oxygenase-1 activity.Jul 22, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomedicines. 2020 Jul 23 ;8(8). Epub 2020 Jul 23. PMID: 32717964

Article Published Date : Jul 22, 2020

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Neurodegenerative Diseases, Oxidative Stress

Pharmacological Actions : Antioxidants, Cytoprotective, Heme oxygenase-1 up-regulation, Neuroprotective Agents

[+]

N-acetylcysteine significantly reduced the incidence of clinically apparent disease.Jun 30, 1997

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Eur Respir J. 1997 Jul ;10(7):1535-41. PMID: 9230243

Article Published Date : Jun 30, 1997

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Influenza A

Pharmacological Actions : Antiviral Agents

[+]

N-Acetylcysteine suppresses microglial inflammation.Feb 13, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2023 Feb 14 ;24(4). Epub 2023 Feb 14. PMID: 36835209

Article Published Date : Feb 13, 2023

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

N-acetylcysteine to combat COVID-19: An evidence review. Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ther Clin Risk Manag. 2020 ;16:1047-1055. Epub 2020 Nov 2. PMID: 33177829

Article Published Date : Dec 31, 2019

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Coronavirus Infection

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Immunomodulatory

[+]

N-Acetylcysteine: multiple clinical applicationsJul 31, 2009

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Am Fam Physician. 2009 Aug 1 ;80(3):265-9. PMID: 19621836

Article Published Date : Jul 31, 2009

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Acetaminophen (Tylenol) Toxicity , Cancers: All, Chemotherapy-Induced Toxicity: Gentamicin, Helicobacter Pylori Infection, Influenza

Pharmacological Actions : Anti-Bacterial Agents, Antioxidants, Chemopreventive, Chemoprotective Agents

[+]

NAC and curcumin ameliorate pesticide-induced oxidative DNA damage in human peripheral blood mononuclear cells.Nov 04, 2010

Click here to read the entire abstract

Pubmed Data : Environ Monit Assess. 2010 Nov 4. Epub 2010 Nov 4. PMID: 21049288

Article Published Date : Nov 04, 2010

Study Type : In Vitro Study

Additional Links

Substances : Curcumin, NAC (N-acetyl-L-cysteine)

Diseases : DNA damage, Pesticide Toxicity

Pharmacological Actions : Antioxidants

[+]

NAC exhibits strong potential for the protection of the diabetic heart at risk of myocardial infarction Apr 05, 2018

Click here to read the entire abstract

Pubmed Data : Am J Cardiovasc Drugs. 2018 Apr 6. Epub 2018 Apr 6. PMID: 29623672

Article Published Date : Apr 05, 2018

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Diabetic Complications, Myocardial Infarction: Prevention

Pharmacological Actions : Cardioprotective

[+]

NAC has good antibacterial properties and the ability to interfere with biofilm formation and disrupt biofilms.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Respir Med. 2016 08 ;117:190-7. Epub 2016 Jun 16. PMID: 27492531

Article Published Date : Dec 31, 2015

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Cystic Fibrosis, Upper Respiratory Infections

Pharmacological Actions : Anti-Bacterial Agents

Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation

[+]

NAC inhibits the LPS-mediated synthesis of tumor TNF-α and IL-1β in hPDLFs, through the NF-κB pathway.Sep 30, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Medicine (Baltimore). 2019 Oct ;98(40):e17126. PMID: 31577702

Article Published Date : Sep 30, 2019

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

NAC possesses beneficial effects in acute and chronic inflammatory diseases of the respiratory tract.Apr 18, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ter Arkh. 2018 Apr 19 ;90(3):89-95. PMID: 30701862

Article Published Date : Apr 18, 2018

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Respiratory Tract Infections

Pharmacological Actions : Immunomodulatory

[+]

Nutritional and medical food therapies for diabetic retinopathy.Dec 31, 2019

Click here to read the entire abstract

Pubmed Data : Eye Vis (Lond). 2020 ;7:33. Epub 2020 Jun 18. PMID: 32582807

Article Published Date : Dec 31, 2019

Study Type : Review

Additional Links

Substances : Alpha-Lipoic Acid, Lutein, NAC (N-acetyl-L-cysteine), Riboflavin (Vitamin B-2), Thiamine (B-1) , Vitamin B12, Vitamin B6, Vitamin C, Vitamin D, Vitamin E, Zeaxanthin

Diseases : Diabetic Retinopathy

Pharmacological Actions : Antioxidants, Neuroprotective Agents

[+]

Perspectives for the use of N-acetylcysteine as a candidate drug to treat COVID-19.Oct 26, 2020

Click here to read the entire abstract

Pubmed Data : Mini Rev Med Chem. 2020 Oct 27. Epub 2020 Oct 27. PMID: 33109047

Article Published Date : Oct 26, 2020

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Coronavirus Infection

Pharmacological Actions : Antiviral Agents

[+]

Possible beneficial effects of N-acetylcysteine for treatment of triple-negative breast cancer.Jan 23, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Antioxidants (Basel). 2021 Jan 24 ;10(2). Epub 2021 Jan 24. PMID: 33498875

Article Published Date : Jan 23, 2021

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Breast Cancer: Triple Negative

Pharmacological Actions : Antioxidants, Chemotherapeutic

[+]

Post-inflammatory administration of N-acetylcysteine reduces inflammation and alters receptor levels in a cellular model of Parkinson's disease.Jun 30, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : FASEB Bioadv. 2023 Jul ;5(7):263-276. Epub 2023 May 16. PMID: 37415931

Article Published Date : Jun 30, 2023

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Parkinson's Disease

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

[+]

Potential of nano-antioxidants and nanomedicine for recovery from neurological disorders linked to long COVID syndrome.Feb 05, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Antioxidants (Basel). 2023 Feb 6 ;12(2). Epub 2023 Feb 6. PMID: 36829952

Article Published Date : Feb 05, 2023

Study Type : Review

Additional Links

Substances : Curcumin, Ginkgo biloba, Melatonin, NAC (N-acetyl-L-cysteine), Quercetin, Rosemaric Acid, Vitamin C, Vitamin D, Vitamin E

Diseases : Coronavirus Infection

Pharmacological Actions : Antioxidants, Neuroprotective Agents

Additional Keywords : Long Covid

[+]

Potential role of antioxidant and anti-inflammatory therapies to prevent severe SARS-Cov-2 complications. Feb 09, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Antioxidants (Basel). 2021 Feb 10 ;10(2). Epub 2021 Feb 10. PMID: 33578849

Article Published Date : Feb 09, 2021

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine), Vitamin C

Diseases : Coronavirus Infection

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

Proteomics study of N-acetylcysteine response in H1N1-infected cells by using mass spectrometry.Apr 14, 2014

Click here to read the entire abstract

Pubmed Data : Rapid Commun Mass Spectrom. 2014 Apr 15 ;28(7):741-9. PMID: 24573805

Article Published Date : Apr 14, 2014

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Influenza

Pharmacological Actions : Anti-Apoptotic

[+]

Resveratrol and N-acetylcysteine block the cancer-initiating step in breast cancer cells.Jan 01, 2011

Click here to read the entire abstract

Pubmed Data : Free Radic Biol Med. 2011 Jan 1;50(1):78-85. Epub 2010 Oct 8. PMID: 20934508

Article Published Date : Jan 01, 2011

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine), Resveratrol

Diseases : Breast Cancer

Pharmacological Actions : Chemopreventive

Additional Keywords : Natural Substance Synergy

[+]

Resveratrol and NAC may prevent age-associated decline in skin and/or connective tissue quality.Jun 01, 2010

Click here to read the entire abstract

Pubmed Data : Minerva Ginecol. 2010 Jun;62(3):195-201. PMID: 20595944

Article Published Date : Jun 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine), Resveratrol

Diseases : Aging Skin, Postmenopausal Disorders

Pharmacological Actions : Antiproliferative , Enzyme Inhibitors

Additional Keywords : Stilbenes

[+]

Resveratrol and NAC may prevent DNA-estrogen adducts associated with carcinogenesis. Jan 01, 2010

Click here to read the entire abstract

Pubmed Data : Future Oncol. 2010 Jan;6(1):75-91. PMID: 20021210

Article Published Date : Jan 01, 2010

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine), Resveratrol, Stilbenes

Diseases : Breast Cancer, Cancers: All, Cancers: Estrogen Responsive, DNA damage, Estrogen Dominance

Pharmacological Actions : Antineoplastic Agents, Antioxidants

[+]

Storing red blood cells with vitamin C and N-acetylcysteine prevents oxidative stress-related lesions.Jun 30, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Blood Transfus. 2014 Jul ;12(3):376-87. Epub 2014 Jun 5. PMID: 25074788

Article Published Date : Jun 30, 2014

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine), Vitamin C

Diseases : Blood Storage Problems

Pharmacological Actions : Antioxidants

[+]

Targeting oxidative stress in septic acute kidney injury: from theory to practice.Aug 24, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Med. 2021 Aug 25 ;10(17). Epub 2021 Aug 25. PMID: 34501245

Article Published Date : Aug 24, 2021

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Kidney Damage, Sepsis

Pharmacological Actions : Renoprotective

[+]

Targeting oxidative stress involved in endometriosis and its pain. Jul 28, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomolecules. 2022 Jul 29 ;12(8). Epub 2022 Jul 29. PMID: 36008949

Article Published Date : Jul 28, 2022

Study Type : Review

Additional Links

Substances : Curcumin, Melatonin, NAC (N-acetyl-L-cysteine), Vitamin C

Diseases : Endometriosis, Oxidative Stress

Pharmacological Actions : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Antioxidants, Antiproliferative

[+]

The antioxidants NAC and glutathione attenuate oxidative stress and endothelial dysfunction caused by active antiretroviral therapy. Jan 01, 2004

Click here to read the entire abstract

Pubmed Data : Cardiovasc Toxicol. 2004;4(3):287-302. PMID: 15470276

Article Published Date : Jan 01, 2004

Study Type : In Vitro Study

Additional Links

Substances : Glutathione, NAC (N-acetyl-L-cysteine)

Diseases : Endothelial Dysfunction, HIV Drug-Induced Toxicity

Pharmacological Actions : Antioxidants, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Drug: Efavirenz, Drug: Indinavir, Drug: Nelfinavir, Drug: Zidovudine, Drug Side Effect Attenuation

[+]

The effects of twenty-one nutrients and phytonutrients on cognitive function: A narrative review.Aug 25, 2021

Click here to read the entire abstract

Pubmed Data : J Clin Transl Res. 2021 Aug 26 ;7(4):575-620. Epub 2021 Aug 4. PMID: 34541370

Article Published Date : Aug 25, 2021

Study Type : Review

Additional Links

Substances : Aloe Vera, Ashwagandha, Bacopa, Lion's Mane (Hericium Erinaceus), NAC (N-acetyl-L-cysteine), Omega-3 Fatty Acids, Rosemary, Saffron, Tart Cherry, Turmeric, Vitamin D, Vitamin E

Diseases : Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

[+]

The review of available literature suggests that N-acetylcysteine could potentially serve as a safe, tolerable, and effective therapeutic option for a variety of dermatologic conditions.May 01, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Aesthet Dermatol. 2019 May ;12(5):20-26. Epub 2019 May 1. PMID: 31320973

Article Published Date : May 01, 2019

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Skin Diseases

[+]

These results demonstrate the potential of allyl isothiocyanate and N-acetylcysteine- allyl isothiocyanate as chemopreventive agents.Mar 31, 2006

Click here to read the entire abstract

Pubmed Data : Exp Biol Med (Maywood). 2006 Apr ;231(4):421-30. PMID: 16565438

Article Published Date : Mar 31, 2006

Study Type : In Vitro Study

Additional Links

Substances : Isothiocyanates, NAC (N-acetyl-L-cysteine)

Diseases : Cancer Metastasis, Liver Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

[+]

This work supports the use of antioxidants in order to ameliorate the inflammatory effects of different viral infections during COPD exacerbations.Aug 31, 2011

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biochem Pharmacol. 2011 Sep 1 ;82(5):548-55. Epub 2011 May 25. PMID: 21635874

Article Published Date : Aug 31, 2011

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Chronic Obstructive Pulmonary Disease, Influenza A, Influenza B

Pharmacological Actions : Antiviral Agents, NF-kappaB Inhibitor

[+]

Trichostatin A works synergistically with curcumin to inhibit human leukemia cells.Aug 01, 2006

Click here to read the entire abstract

Pubmed Data : Pharmazie. 2006 Aug;61(8):710-6. PMID: 16964716

Article Published Date : Aug 01, 2006

Study Type : In Vitro Study

Additional Links

Substances : Curcumin, NAC (N-acetyl-L-cysteine), Vitamin C

Diseases : Promyelocytic leukemia

Pharmacological Actions : Antioxidants, Antiproliferative

Additional Keywords : Drug Synergy

[+]

Various antioxidants may be preventive and therapeutic in treating influenza A (H5N1) infection (e.g. selenium, vitamin E, NAC/glutathione, resveratrol, and quercetin)Aug 01, 2003

Click here to read the entire abstract

Pubmed Data : J Nat Prod. 2003 Aug;66(8):1124-7. PMID: 16624496

Article Published Date : Aug 01, 2003

Study Type : Commentary

Additional Links

Substances : Antioxidant formulas, Glutathione, NAC (N-acetyl-L-cysteine), Quercetin, Resveratrol, Selenium, Vitamin E

Diseases : Avian Influenza, Virally-Induced Cytokine Storm

[+]

Virological and immunological effects of antioxidant treatment in patients with HIV infection.Sep 30, 2000

Click here to read the entire abstract

Pubmed Data : Eur J Clin Invest. 2000 Oct ;30(10):905-14. PMID: 11029606

Article Published Date : Sep 30, 2000

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine), Vitamin C

Diseases : HIV Infections

Pharmacological Actions : Immunomodulatory

[+]

Vitamin D and L-cysteine could be useful in preventing the 'cytokine storm,' one of the most severe consequences of infection with COVID-19.Jul 12, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Am Coll Nutr. 2020 Jul 13:1-6. Epub 2020 Jul 13. PMID: 32659175

Article Published Date : Jul 12, 2020

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine), Vitamin D

Additional Keywords : Cytokine Modulation, Cytokine Storm, Risk Reduction

[+]

Water-soluble antioxidants improve the antioxidant and anticancer activity of low concentrations of curcumin in human leukemia cells.Jan 01, 2005

Click here to read the entire abstract

Pubmed Data : Pharmazie. 2005 Jan;60(1):57-61. PMID: 15700780

Article Published Date : Jan 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Curcumin, NAC (N-acetyl-L-cysteine), Vitamin C

Diseases : Leukemia, Oxidative Stress

Pharmacological Actions : Antineoplastic Agents, Antioxidants, Antiproliferative

Additional Keywords : Bioavailability, Natural Substance Synergy

[+]

Acetylcysteine is beneficial in treating idiopathic pulmonary fibrosis. - Article 1Nov 24, 2005

Click here to read the entire abstract

Pubmed Data : N Engl J Med. 2005 Nov 24;353(21):2229-42. PMID: 16306520

Article Published Date : Nov 24, 2005

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Interstitial Lung Diseases

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View the Evidence: 362 Abstracts with NAC (N-acetyl-L-cysteine) Research

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N-acetycysteine: A potential therapeutic agent in COVID-19 infection.Jul 23, 2020

N-acetyl cysteine and vitamin D supplementation in treatment resistant obsessive compulsive disorder patients.Jan 16, 2018

N-acetyl cysteine has antiproliferative on pancreatic cancer cells. Dec 01, 2000

N-acetyl cysteine, selenium, and ascorbic acid rescue diabetic cardiac hypertrophy.Nov 29, 2021

N-acetyl-L-cysteine attenuated influenza virus-induced NF-kappa B activation.Dec 31, 1997

N-acetyl-l-cystine (NAC) protects against H9N2 swine influenza virus-induced acute lung injury.Aug 31, 2014

N-acetylcysteine (NAC) attenuates quorum sensing regulated phenotypes in Pseudomonas aeruginosa PAO1.Feb 28, 2023

N-acetylcysteine alleviated paraquat-induced mitochondrial fragmentation and autophagy in primary murine neural progenitor cells.Jul 31, 2019

N-acetylcysteine ameliorates cisplatin-induced renal senescence and renal interstitial fibrosis.Dec 31, 2018

N-acetylcysteine and coronavirus disease 2019: May it work as a beneficial preventive and adjuvant therapy?Dec 31, 2019

N-acetylcysteine as adjuvant therapy for COVID-19.Dec 31, 2020

N-acetylcysteine attenuates cisplatin-induced acute kidney injury by inhibiting the C5a receptor.Dec 31, 2018

N-acetylcysteine attenuates lipopolysaccharide-induced osteolysis by restoring bone remodelling balance. Feb 25, 2020

N-acetylcysteine blocks SOS induction and mutagenesis produced by fluoroquinolones in Escherichia coli.Jul 31, 2019

N-acetylcysteine can induce massive oxidative stress, resulting in cell death with apoptotic features in human leukemia cells.Nov 22, 2021

N-Acetylcysteine could be used in the management of bacterial spot of tomato caused by copper-resistant Xanthomonas perforans.Nov 10, 2020

N-acetylcysteine for non-acetaminophen induced acute liver failure.Feb 06, 2022

N-acetylcysteine for obsessive-compulsive and related disorders in children and adolescents.Nov 15, 2022

N-acetylcysteine for the management of non-acetaminophen drug-induced liver injury.Dec 31, 2021

N-acetylcysteine improves the inhibitory effect of quercetin-rich onion extract on HT-29 and HCT-116 colorectal cancer migration and invasion.Dec 31, 2022

N-acetylcysteine in substance use disorder: a lesson from preclinical and clinical researchJun 05, 2021

N-acetylcysteine inhalation improves the quality of life of patients with head and neck cancers who are receiving radiation therapy.Aug 13, 2020

N-acetylcysteine is recommended for all patients with acetaminophen-induced acute liver failure and it reduces mortality. Dec 31, 2017

N-Acetylcysteine prevents amyloid-β secretion in neurons derived from human pluripotent stem cells with trisomy 21.Aug 29, 2021

N-acetylcysteine promotes oral absorption of curcumin.Aug 04, 2020

N-Acetylcysteine protects against cobalt chloride-induced endothelial dysfunction by enhancing glucose-6-phosphate dehydrogenase activity.Jun 03, 2022

N-acetylcysteine protects bladder epithelial cells from bacterial invasion and displays antibiofilm activity against urinary tract bacterial pathogens. Jul 22, 2021

N-acetylcysteine protects hepatocytes from hypoxia-related cell injuryNov 30, 2018

N-acetylcysteine provides cytoprotection in murine oligodendrocytes through heme oxygenase-1 activity.Jul 22, 2020

N-acetylcysteine significantly reduced the incidence of clinically apparent disease.Jun 30, 1997

N-Acetylcysteine suppresses microglial inflammation.Feb 13, 2023

N-acetylcysteine to combat COVID-19: An evidence review. Dec 31, 2019

N-Acetylcysteine: multiple clinical applicationsJul 31, 2009

NAC and curcumin ameliorate pesticide-induced oxidative DNA damage in human peripheral blood mononuclear cells.Nov 04, 2010

NAC exhibits strong potential for the protection of the diabetic heart at risk of myocardial infarction Apr 05, 2018

NAC has good antibacterial properties and the ability to interfere with biofilm formation and disrupt biofilms.Dec 31, 2015

NAC inhibits the LPS-mediated synthesis of tumor TNF-α and IL-1β in hPDLFs, through the NF-κB pathway.Sep 30, 2019

NAC possesses beneficial effects in acute and chronic inflammatory diseases of the respiratory tract.Apr 18, 2018

Nutritional and medical food therapies for diabetic retinopathy.Dec 31, 2019

Perspectives for the use of N-acetylcysteine as a candidate drug to treat COVID-19.Oct 26, 2020

Possible beneficial effects of N-acetylcysteine for treatment of triple-negative breast cancer.Jan 23, 2021

Post-inflammatory administration of N-acetylcysteine reduces inflammation and alters receptor levels in a cellular model of Parkinson's disease.Jun 30, 2023

Potential of nano-antioxidants and nanomedicine for recovery from neurological disorders linked to long COVID syndrome.Feb 05, 2023

Potential role of antioxidant and anti-inflammatory therapies to prevent severe SARS-Cov-2 complications. Feb 09, 2021

Proteomics study of N-acetylcysteine response in H1N1-infected cells by using mass spectrometry.Apr 14, 2014

Resveratrol and N-acetylcysteine block the cancer-initiating step in breast cancer cells.Jan 01, 2011

Resveratrol and NAC may prevent age-associated decline in skin and/or connective tissue quality.Jun 01, 2010

Resveratrol and NAC may prevent DNA-estrogen adducts associated with carcinogenesis. Jan 01, 2010

Storing red blood cells with vitamin C and N-acetylcysteine prevents oxidative stress-related lesions.Jun 30, 2014

Targeting oxidative stress in septic acute kidney injury: from theory to practice.Aug 24, 2021

Targeting oxidative stress involved in endometriosis and its pain. Jul 28, 2022

The antioxidants NAC and glutathione attenuate oxidative stress and endothelial dysfunction caused by active antiretroviral therapy. Jan 01, 2004

The effects of twenty-one nutrients and phytonutrients on cognitive function: A narrative review.Aug 25, 2021

The review of available literature suggests that N-acetylcysteine could potentially serve as a safe, tolerable, and effective therapeutic option for a variety of dermatologic conditions.May 01, 2019

These results demonstrate the potential of allyl isothiocyanate and N-acetylcysteine- allyl isothiocyanate as chemopreventive agents.Mar 31, 2006

This work supports the use of antioxidants in order to ameliorate the inflammatory effects of different viral infections during COPD exacerbations.Aug 31, 2011

Trichostatin A works synergistically with curcumin to inhibit human leukemia cells.Aug 01, 2006

Various antioxidants may be preventive and therapeutic in treating influenza A (H5N1) infection (e.g. selenium, vitamin E, NAC/glutathione, resveratrol, and quercetin)Aug 01, 2003

Virological and immunological effects of antioxidant treatment in patients with HIV infection.Sep 30, 2000

Vitamin D and L-cysteine could be useful in preventing the 'cytokine storm,' one of the most severe consequences of infection with COVID-19.Jul 12, 2020

Water-soluble antioxidants improve the antioxidant and anticancer activity of low concentrations of curcumin in human leukemia cells.Jan 01, 2005

Acetylcysteine is beneficial in treating idiopathic pulmonary fibrosis. - Article 1Nov 24, 2005

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NAC (N-acetyl-L-cysteine)

View the Evidence:
362 Abstracts with NAC (N-acetyl-L-cysteine) Research