Noni

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101 Diseases Researched for Noni
NameACCKFocus
Inflammation1220Locked
Oxidative Stress515Locked
Hypertension314Locked
Dyslipidemias212Locked
Nicotine/Tobacco Toxicity 212Locked
Smoking212Locked
Leishmaniasis211Locked
Alcohol Toxicity 110Locked
C-Reactive Protein110Locked
Coronavirus Infection110Locked
Cystitis110Locked
Diabetes Mellitus: Type 2110Locked
Hangover110Locked
Nausea: Post-Operative110Locked
Postoperative Recovery110Locked
Vomiting110Locked
Lung Cancer59Locked
Breast Cancer67Locked
Obesity47Locked
Carcinoma: Non-Small-Cell Lung26Locked
Osteoarthritis36Locked
Cancers: All35Locked
Arthritis24Locked
Athletic Performance24Locked
Cerebral Ischemia24Locked
Colitis24Locked
Immune Disorders: Low Immune Function24Locked
Osteoporosis24Locked
Pancreatic Cancer24Locked
Wound Healing24Locked
DNA damage23Locked
Inflammatory Bowel Diseases23Locked
Lipopolysaccharide-Induced Toxicity23Locked
Liver Cancer33Locked
Pain23Locked
Parkinson's Disease23Locked
Aging: Immunosenecence12Locked
Alcoholic Liver Disease12Locked
Athletic Performance: Recovery 12Locked
Atopic Dermatitis12Locked
Bone Diseases12Locked
Brain Ischemia12Locked
Breast Cancer: Triple Negative 22Locked
Cancer Metastasis12Locked
Candida Infection 22Locked
Cardiovascular Diseases12Locked
Chemically-Induced Liver Damage12Locked
Chemotherapy-Induced Liver Toxicity12Locked
Cholesterol: LDL/HDL ratio12Locked
Cognitive Decline/Dysfunction12Locked
Depression12Locked
Diabetes Mellitus: Type 112Locked
Fatigue12Locked
Gastric Ulcer12Locked
Gastroesophageal Reflux12Locked
HDL: Low12Locked
High Cholesterol12Locked
High Fat Diet12Locked
Hyperglycemia12Locked
Hyperlipidemia12Locked
Liver Fibrosis12Locked
Memory Disorders12Locked
Neurodegeneration: Dentate Gyrus12Locked
Obsessive-Compulsive Disorder12Locked
Parasitic Diseases12Locked
Prenatal Nutrition 12Locked
Rheumatoid Arthritis12Locked
Sarcoma12Locked
Stress12Locked
Tumors12Locked
Acquired Immunodeficiency Syndrome11Locked
Advanced Glycation End products (AGE)11Locked
Anxiety Disorders11Locked
Aspergillosis11Locked
Cholera11Locked
Colon Cancer11Locked
Colorectal Cancer11Locked
Dental Caries11Locked
Enterococcus Infections11Locked
Epstein-Barr Virus Infections11Locked
Foodborne Pathogens: Prevention/Food Preservation11Locked
Gastrointestinal Inflammation11Locked
Generalized Anxiety Disorder11Locked
Gout11Locked
Gram-Positive Bacterial Infections11Locked
Hepatitis C11Locked
Laryngeal Cancer11Locked
Leukemia11Locked
Liposarcoma 11Locked
Listeria Infections11Locked
Metabolic Diseases11Locked
Neuroblastoma11Locked
Oral Cancer11Locked
Periodontal Diseases11Locked
Promyelocytic leukemia 11Locked
Pseudogout11Locked
Squamous cell carcinoma11Locked
Streptococcus Infections11Locked
Tuberculosis11Locked
Vibrio Infections11Locked
Wound Healing: Periodontal11Locked
66 Pharmacological Actions Researched for Noni
NameACCKFocus
Antioxidants1641Locked
Anti-Inflammatory Agents1932Locked
Nitric Oxide Inhibitor517Locked
Antiproliferative 1114Locked
Hypoglycemic Agents314Locked
Immunomodulatory714Locked
Antihypertensive Agents212Locked
Interleukin-6 Downregulation212Locked
Interleukin-8 downregulation211Locked
Leishmanicidal211Locked
Antiemetics110Locked
Antiprotozoal Agents110Locked
Hepatoprotective510Locked
Apoptotic89Locked
Cyclooxygenase 2 Inhibitors49Locked
Neuroprotective Agents47Locked
NF-kappaB Inhibitor46Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor36Locked
Chemotherapeutic35Locked
Anti-Bacterial Agents44Locked
Epidermal growth factor receptor (EGFR) inhibitor14Locked
Gastrointestinal Agents24Locked
Immunostimulatory24Locked
Anti-Apoptotic23Locked
Anti-Tumor13Locked
Anti-metastatic33Locked
Anticarcinogenic Agents23Locked
Antiviral Agents33Locked
Cell cycle arrest23Locked
Acetylcholinesterase Inhibitor12Locked
Analgesics12Locked
Anti-Fibrotic12Locked
Anti-Inflammatory Agents: Non-Steroidal12Locked
Anti-Ulcer Agents12Locked
Antidepressive Agents12Locked
Antiparasitic Agents12Locked
Antispasmodic12Locked
Calcium Channel Blockers12Locked
Chondroprotective12Locked
Forkhead Transcription Factor Family O (FOXO) Modulator12Locked
Hypolipidemic12Locked
Insulin-releasing12Locked
Interferon Gamma Reducer12Locked
Interferon Inducers12Locked
Interleukin-17 downregulation12Locked
Malondialdehyde Down-regulation12Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor12Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor12Locked
MicroRNA modulator12Locked
Osteoprotective 12Locked
Vasodilator Agents12Locked
Angiogenesis Inhibitors11Locked
Anti-Angiogenic11Locked
Antifungal Agents11Locked
Antimicrobial11Locked
Anxiolytic11Locked
Chemopreventive11Locked
DNA Repair Up-regulation11Locked
GABA Modulators11Locked
Interleukin-10 upregulation11Locked
Interleukin-4 upregulation11Locked
Nrf2 activation11Locked
Quinone Reductase-Inducer11Locked
Regenerative11Locked
Wnt/β-catenin signaling pathway modulation11Locked
Xanthine oxidase inhibitor11Locked
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View the Evidence:
104 Abstracts with Noni Research

[+]

Consumption of noni and chokeberry juices lower blood pressure while energy drinks increase it. Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:6076751. Epub 2019 Aug 18. PMID: 31531115
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Chokeberry, Noni
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents
Problem Substances : Energy Drinks
[+]

Efficacy of N-acetylcysteine, D-mannose and Morinda citrifolia to treat recurrent cystitis in breast cancer survivors. Aug 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : In Vivo. 2017 Sep-Oct;31(5):931-936. PMID: 28882961
Article Published Date : Aug 31, 2017
Study Type : Human Study
Additional Links
Substances : Cysteine (see N-Acetylcysteine), D-Mannose, Noni
Diseases : Cystitis
[+]

Fermented Carica papaya and Morinda citrifolia as perspective food supplements for the treatment of post-COVID symptoms.May 24, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 May 25 ;14(11). Epub 2022 May 25. PMID: 35684003
Article Published Date : May 24, 2022
Study Type : Human Study
Additional Links
Substances : Fermented Foods and Beverages, Noni, Papaya
Diseases : Coronavirus Infection
Pharmacological Actions : Antioxidants, Interleukin-6 Downregulation, Interleukin-8 downregulation, Nitric Oxide Inhibitor
[+]

In this study of 40 patients 50% of them showed an excellent response and 30% exhibited good improvement to the treatment..Jan 31, 2012

Pubmed Data : Nat Prod Commun. 2012 Feb ;7(2):195-6. PMID: 22474954
Article Published Date : Jan 31, 2012
Study Type : Human Study
Additional Links
Substances : Noni
Diseases : Leishmaniasis
Pharmacological Actions : Antiprotozoal Agents, Leishmanicidal
Additional Keywords : Plant Extracts
[+]

Noni effectively reduces the incidence of early postoperative nausea.Dec 01, 2010

Pubmed Data : J Med Assoc Thai. 2010 Dec ;93 Suppl 7:S204-9. PMID: 21294416
Article Published Date : Dec 01, 2010
Study Type : Human Study
Additional Links
Substances : Noni
Diseases : Nausea: Post-Operative, Postoperative Recovery, Vomiting
Pharmacological Actions : Antiemetics
Additional Keywords : Plant Extracts
[+]

Noni fruit extract has the potential to improve hangover symptoms by decreasing alcohol and acetaldehyde levels.Feb 05, 2023

Pubmed Data : Food Funct. 2023 Feb 6 ;14(3):1750-1760. Epub 2023 Feb 6. PMID: 36727425
Article Published Date : Feb 05, 2023
Study Type : Human Study
Additional Links
Substances : Noni
Diseases : Alcohol Toxicity , Hangover
Additional Keywords : Plant Extracts
[+]

Noni fruit juice has the potential to regulate elevated blood sugar levels and some other pathological parameters in patients with type 2 diabetes.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2018 ;2018:3565427. Epub 2018 Aug 6. PMID: 30158993
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Noni
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
[+]

Noni juice improves serum lipid profiles and other risk markers in cigarette smokers.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ScientificWorldJournal. 2012 ;2012:594657. Epub 2012 Oct 11. PMID: 23097636
Article Published Date : Dec 31, 2011
Study Type : Human Study
Additional Links
Substances : Noni
Diseases : C-Reactive Protein, Dyslipidemias, Nicotine/Tobacco Toxicity , Oxidative Stress, Smoking
Pharmacological Actions : Antioxidants
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Safety Study: Noni.Nov 01, 2009

Pubmed Data : Pac Health Dialog. 2009 Nov;15(2):21-32. PMID: 20443518
Article Published Date : Nov 01, 2009
Study Type : Human Study
Additional Links
Substances : Noni
Additional Keywords : Plant Extracts
[+]

One of three enrolled patients with advanced stomach cancer had no evidence of disease progression for 36 months while taking noni.Dec 31, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Diet Suppl. 2009 ;6(4):347-59. PMID: 22435516
Article Published Date : Dec 31, 2008
Study Type : Human: Case Report
Additional Links
Substances : Noni
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-Tumor
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Effect of Morinda citrifolia and Annona muricata on erhlich tumor cells in swiss albino mice and in vitro fibroblast cells.Nov 08, 2018

Pubmed Data : J Med Food. 2018 Nov 9. Epub 2018 Nov 9. PMID: 30412453
Article Published Date : Nov 08, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Noni, Soursop
Diseases : Cancers: All
Pharmacological Actions : Chemotherapeutic
[+]

Epicatechin and scopoletin rich Morinda citrifolia leaf extract supplementation, mitigated OsteoarthritisFeb 28, 2019

Pubmed Data : J Food Biochem. 2019 Mar ;43(3):e12755. Epub 2019 Jan 3. PMID: 31353568
Article Published Date : Feb 28, 2019
Study Type : Animal Study
Additional Links
Substances : Epicatechin, Noni
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chondroprotective
Additional Keywords : Plant Extracts
[+]

Fermented Morinda citrifolia alleviates DNCB-induced atopic dermatitis. Jan 17, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Jan 18 ;12(1). Epub 2020 Jan 18. PMID: 31963703
Article Published Date : Jan 17, 2020
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Atopic Dermatitis
Pharmacological Actions : Immunomodulatory
[+]

Fermented noni juice has blood sugar lowering and liver protecting properties in diabetic rats.Jan 01, 2011

Pubmed Data : Evid Based Complement Alternat Med. 2011;2011:875293. Epub 2010 Oct 14. PMID: 20981320
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Hepatoprotective, Hypoglycemic Agents
[+]

M. citrifolia leaf extracts shows promise as an anti-obesity agents.Dec 31, 2016

Pubmed Data : Food Nutr Res. 2017 ;61(1):1338919. Epub 2017 Jul 27. PMID: 28814950
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Obesity
Additional Keywords : Anti-Obesity Agents
[+]

MicroRNAs involved in the therapeutic functions of noni fruit juice in the treatment of acute gouty arthritis. Jul 14, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2021 Jul 15 ;10(7). Epub 2021 Jul 15. PMID: 34359507
Article Published Date : Jul 14, 2021
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, MicroRNA modulator, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Morinda citrifolia can be used to alleviate skeletal muscle damage induced by Parkinsonism.Dec 22, 2015

Pubmed Data : Food Funct. 2015 Dec 23. Epub 2015 Dec 23. PMID: 26697948
Article Published Date : Dec 22, 2015
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Antioxidants
[+]

Morinda citrifolia extract prevents alcoholic fatty liver disease by improving gut health.Nov 30, 2022

Pubmed Data : J Med Food. 2022 Dec ;25(12):1102-1111. PMID: 36516056
Article Published Date : Nov 30, 2022
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Alcoholic Liver Disease, Inflammation
Pharmacological Actions : Gastrointestinal Agents, Hepatoprotective
Additional Keywords : Gut-liver axis
[+]

Morinda citrifolia leaf was more effective than the erlotinib in suppressing lung adenocarcinoma in mice. Jan 13, 2016

Pubmed Data : Food Funct. 2016 Jan 14. Epub 2016 Jan 14. PMID: 26765787
Article Published Date : Jan 13, 2016
Study Type : Animal Study
Additional Links
Substances : Noni, Noni leaf extract
Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer
Pharmacological Actions : Antiproliferative , Cyclooxygenase 2 Inhibitors, Epidermal growth factor receptor (EGFR) inhibitor, Immunomodulatory
Additional Keywords : Dose Response, Superiority of Natural Substances versus Drugs
[+]

Morinda citrifolia noni water extract enhances innate and adaptive immune responses in healthy mice.Jan 09, 2019

Pubmed Data : Phytother Res. 2019 Jan 10. Epub 2019 Jan 10. PMID: 30632216
Article Published Date : Jan 09, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Noni
Pharmacological Actions : Immunostimulatory
[+]

Naturally fermented Noni juice manifests a protective potential on liver fibrosis.Mar 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Chin Med Assoc. 2017 Apr ;80(4):212-221. Epub 2017 Mar 6. PMID: 28268174
Article Published Date : Mar 31, 2017
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages, Noni
Diseases : Liver Fibrosis
Pharmacological Actions : Anti-Fibrotic, Antioxidants, Hepatoprotective, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Noni (Morinda citrifolia) reduces cancer risk in current smokers by decreasing aromatic DNA adducts.Jan 01, 2009

Pubmed Data : Nutr Cancer. 2009;61(5):634-9. PMID: 19838937
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : DNA damage, Nicotine/Tobacco Toxicity , Smoking
Pharmacological Actions : Anticarcinogenic Agents
Additional Keywords : Risk Reduction
[+]

Noni (Morindia citrifolia) leaf enhances wound-healing. Sep 01, 2009

Pubmed Data : Evid Based Complement Alternat Med. 2009 Sep;6(3):351-6. Epub 2007 Oct 25. PMID: 18955257
Article Published Date : Sep 01, 2009
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Wound Healing
Additional Keywords : Accelerated Healing
[+]

Noni (Morindia citrifolia) works synergistically with doxorubicin to inhibit mammary tumor growth in mice. Dec 01, 2009

Pubmed Data : Cell Biochem Funct. 2009 Dec;27(8):542-6. PMID: 19908222
Article Published Date : Dec 01, 2009
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Breast Cancer
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Noni exhibits anti-parasitic activity in chickens.Oct 01, 2009

Pubmed Data : Rev Bras Parasitol Vet. 2009 Oct-Dec;18(4):32-6. PMID: 20040206
Article Published Date : Oct 01, 2009
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Parasitic Diseases
Pharmacological Actions : Antiparasitic Agents
Additional Keywords : Plant Extracts
[+]

Noni exhibits potent antitumour potential in Sarcoma.Dec 01, 2003

Pubmed Data : Phytother Res. 2003 Dec;17(10):1158-64. PMID: 14669249
Article Published Date : Dec 01, 2003
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Sarcoma, Tumors
[+]

Noni extract has benefits for physical activities and disease recovery.Nov 30, 2016

Pubmed Data : Food Chem. 2016 Dec 1 ;212:443-52. Epub 2016 Jun 2. PMID: 27374554
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Athletic Performance, Athletic Performance: Recovery
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Plant Extracts
[+]

Noni fruit juice delays immunosenescence in the lymphocytes in lymph nodes of old F344 rats.Dec 31, 2017

Pubmed Data : J Integr Med. 2018 05 ;16(3):199-207. Epub 2018 Apr 12. PMID: 29691190
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Aging: Immunosenecence
Pharmacological Actions : Immunostimulatory
[+]

Noni fruit juice prevents ischemic neuronal damage through suppression of the development of post-ischemic glucose intolerance.Oct 01, 2010

Pubmed Data : J Nat Med. 2010 Oct;64(4):468-73. Epub 2010 Jun 24. PMID: 20574728
Article Published Date : Oct 01, 2010
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Brain Ischemia, Cerebral Ischemia
Pharmacological Actions : Insulin-releasing, Neuroprotective Agents
[+]

Noni fruit juice promotes vascular endothelium function in hypertension.Apr 15, 2020

Pubmed Data : Phytother Res. 2020 Apr 16. Epub 2020 Apr 16. PMID: 32298014
Article Published Date : Apr 15, 2020
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents
[+]

Noni fruit puree compares favorably in analgesic and anti-inflammatory activity to tramadol and hydrocortisone, respectively, in an animal model of arthritis.Jun 22, 2009

Pubmed Data : Phytother Res. 2009 Jun 22. PMID: 19548275
Article Published Date : Jun 22, 2009
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Arthritis, Inflammation, Osteoporosis, Pain
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents: Non-Steroidal
Additional Keywords : Natural Substances Versus Drugs
[+]

Noni fruit reduces stress-induced impairment of cognitive function accompanied by vasculature improvement in mice.Sep 01, 2010

Pubmed Data : Physiol Behav. 2010 Sep 1;101(2):211-7. Epub 2010 Apr 21. PMID: 20416332
Article Published Date : Sep 01, 2010
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Cognitive Decline/Dysfunction, Neurodegeneration: Dentate Gyrus, Stress
Pharmacological Actions : Neuroprotective Agents
[+]

Noni fruit, leaves and root extracts have anti-dyslipidemic properties.Jan 01, 2010

Pubmed Data : Lipids Health Dis. 2010;9:88. Epub 2010 Aug 20. PMID: 20727145
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Cholesterol: LDL/HDL ratio, Dyslipidemias, HDL: Low, High Cholesterol
Pharmacological Actions : Hypolipidemic
[+]

Noni has antispamodic and vasodilator effects.Jan 13, 2010

Pubmed Data : BMC Complement Altern Med. 2010 Jan 13;10(1):2. Epub 2010 Jan 13. PMID: 20070879
Article Published Date : Jan 13, 2010
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Cardiovascular Diseases, Hypertension
Pharmacological Actions : Antispasmodic, Calcium Channel Blockers, Vasodilator Agents
[+]

Noni has demonstratable wound healing properties, confirming its traditional use in Polynesian medicine.Oct 01, 2010

Pubmed Data : Phytother Res. 2010 Oct;24(10):1437-41. PMID: 20878690
Article Published Date : Oct 01, 2010
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Wound Healing
Additional Keywords : Science Confirms Tradition
[+]

Noni has immunostimulatory activity on T and B lymphocytes, confirming its traditional use in the treatment of infections.Jul 01, 2010

Pubmed Data : Pharm Biol. 2010 Jul;48(7):724-31. PMID: 20645768
Article Published Date : Jul 01, 2010
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Immune Disorders: Low Immune Function
Pharmacological Actions : Immunomodulatory
Additional Keywords : Science Confirms Tradition
[+]

Noni has therapeutic potential in ameliorating reflux esophagitis and gastric ulcer. Mar 24, 2011

Pubmed Data : J Ethnopharmacol. 2011 Mar 24 ;134(2):243-50. Epub 2010 Dec 14. PMID: 21163341
Article Published Date : Mar 24, 2011
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Gastric Ulcer, Gastroesophageal Reflux
Pharmacological Actions : Anti-Ulcer Agents
Additional Keywords : Plant Extracts
[+]

Noni improves endurance, flexibility and balance in the mouse model.Nov 01, 2007

Pubmed Data : Phytother Res. 2007 Nov;21(11):1100-1. PMID: 17604369
Article Published Date : Nov 01, 2007
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Athletic Performance
[+]

Noni induces interferon production and may benefit immune systemFeb 12, 2008

Pubmed Data : J Ethnopharmacol. 2008 Feb 12;115(3):502-6. Epub 2007 Oct 24. PMID: 18063495
Article Published Date : Feb 12, 2008
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Immune Disorders: Low Immune Function
Pharmacological Actions : Immunomodulatory, Interferon Inducers
[+]

Noni juice demonstrated chronic anti-inflammatory activity on sensitized lungs along with a spasmolytic effect.Jul 19, 2016

Pubmed Data : J Ethnopharmacol. 2016 Jul 20. Epub 2016 Jul 20. PMID: 27451258
Article Published Date : Jul 19, 2016
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Dose Response
[+]

Noni juice improves glucose metabolism via Fox01 regulation in high-fat fed, diet-induced obese mice. Oct 20, 2011

Pubmed Data : Br J Nutr. 2011 Oct 20:1-11. Epub 2011 Oct 20. PMID: 22011624
Article Published Date : Oct 20, 2011
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Hyperglycemia
Pharmacological Actions : Forkhead Transcription Factor Family O (FOXO) Modulator, Hypoglycemic Agents
[+]

Noni leaf and black tea enhance bone regeneration in estrogen-deficient rats.Dec 31, 2016

Pubmed Data : Nutrition. 2017 Jan ;33:42-51. Epub 2016 Sep 7. PMID: 27908549
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Black Tea, Noni
Diseases : Bone Diseases, Inflammation, Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Bone Regeneration, Ovariectomy-Induced Changes, Plant Extracts
[+]

Noni leaf extract at 300mg/kg was more effective than Erlotinib for most of the parameters measured in this study. Apr 21, 2016

Pubmed Data : Mol Cell Biochem. 2016 Apr 22. Epub 2016 Apr 22. PMID: 27106908
Article Published Date : Apr 21, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Noni leaf extract
Diseases : Cancer Metastasis, Carcinoma: Non-Small-Cell Lung, Lung Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Apoptotic, Cell cycle arrest
Additional Keywords : Gene Expression Regulation, Plant Extracts, Superiority of Natural Substances versus Drugs
[+]

Noni leaf extract protects against cerebral ischemia and osteoporosis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:1039364. Epub 2018 Mar 25. PMID: 29765488
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Cerebral Ischemia, Osteoporosis
Pharmacological Actions : Neuroprotective Agents, Osteoprotective
[+]

Noni may have a protective effect against memory impairment. Nov 15, 2011

Pubmed Data : J Ethnopharmacol. 2011 Nov 15. Epub 2011 Nov 15. PMID: 22107832
Article Published Date : Nov 15, 2011
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Memory Disorders
Pharmacological Actions : Acetylcholinesterase Inhibitor
[+]

Noni protects the liver from chemotoxicity - Article 1Sep 01, 2008

Pubmed Data : Plant Foods Hum Nutr. 2008 Sep;63(3):141-5. Epub 2008 Jul 25. PMID: 18654853
Article Published Date : Sep 01, 2008
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Chemotherapy-Induced Liver Toxicity
Pharmacological Actions : Hepatoprotective
[+]

Noni protects the liver from chemotoxicity - Article 2Jun 01, 2008

Pubmed Data : Plant Foods Hum Nutr. 2008 Jun;63(2):59-63. Epub 2008 Mar 4. PMID: 18317933
Article Published Date : Jun 01, 2008
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Hepatoprotective
[+]

Noni seed oil has hypolipidemic properties.Jul 01, 2011

Pubmed Data : Nat Prod Commun. 2011 Jul ;6(7):1005-8. PMID: 21834246
Article Published Date : Jul 01, 2011
Study Type : Animal Study
Additional Links
Substances : Noni seed oil
Diseases : Hyperlipidemia
Additional Keywords : Plant Extracts
[+]

Noni wine prevents oxidative stress and obesity.Oct 31, 2020

Pubmed Data : J Food Biochem. 2020 Nov ;44(11):e13460. Epub 2020 Sep 9. PMID: 32902870
Article Published Date : Oct 31, 2020
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Obesity, Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Anti-Obesity Agents
[+]

Noni, and its major bioactive component damnacanthal, exhibits anti-inflammatory properties. Nov 01, 2011

Pubmed Data : Inflamm Allergy Drug Targets. 2011 Nov 1. Epub 2011 Nov 1. PMID: 21999179
Article Published Date : Nov 01, 2011
Study Type : Animal Study
Additional Links
Substances : Damnacanthal, Noni
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Nitric Oxide Inhibitor
[+]

Polysaccharide extracted from Morinda citrifolia linn has anti-inflammatory potential.Sep 30, 2018

Pubmed Data : Carbohydr Polym. 2018 Oct 1 ;197:515-523. Epub 2018 Jun 9. PMID: 30007642
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts, Polysaccharides
[+]

Polysaccharide-rich fractions of noni juice might be a potential candidates to be used as an adjuvant to doxorubicin chemotherapy.Dec 31, 2014

Pubmed Data : Sci Pharm. 2015 ;83(3):479-88. Epub 2015 Mar 12. PMID: 26839832
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Cancers: All
Pharmacological Actions : Chemotherapeutic, Immunomodulatory
[+]

Polysaccharides derived from Morinda citrifolia Linn reduce inflammatory markers during experimental colitis.Oct 11, 2019

Pubmed Data : J Ethnopharmacol. 2019 Oct 12 ;248:112303. Epub 2019 Oct 12. PMID: 31614204
Article Published Date : Oct 11, 2019
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor
Additional Keywords : Polysaccharides
[+]

Potential effects of noni fruit extract against obsessive-compulsive disorder.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:993927. Epub 2022 Sep 16. PMID: 36188588
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Obsessive-Compulsive Disorder
[+]

Safety Study: Noni exhibits no adverse effect on fertility and fetal development; on the contrary, noni juice appears to facilitate pregnancy and fetal development.Jan 01, 2011

Pubmed Data : J Toxicol Sci. 2011 Jan ;36(1):81-5. PMID: 21297344
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Prenatal Nutrition
Additional Keywords : Herb Safety, Safety of Natural Substances
[+]

Scopoletin-standardized Morinda elliptica leaf extract suppressed inflammation and cartilage degradation to alleviate osteoarthritis.Nov 30, 2017

Pubmed Data : Phytother Res. 2017 Dec ;31(12):1954-1961. Epub 2017 Oct 25. PMID: 29067744
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Standardized Morinda citrifolia L. and Morinda elliptica L. leaf extracts alleviated fatigue.Jul 10, 2018

Pubmed Data : Phytother Res. 2018 Jul 11. Epub 2018 Jul 11. PMID: 29993148
Article Published Date : Jul 10, 2018
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Fatigue
[+]

The current study revealed that Pikad Tri-phol-sa-mut-than possesses anti-inflammatory activities against acute and chronic inflammation.Nov 14, 2022

Pubmed Data : J Ethnopharmacol. 2022 Nov 15 ;298:115639. Epub 2022 Aug 12. PMID: 35964822
Article Published Date : Nov 14, 2022
Study Type : Animal Study
Additional Links
Substances : Bael , Coriandrum sativum, Noni
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

The present study was the first report where noni juice may be effective against rheumatoid arthritis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2019 ;42(3):496-500. PMID: 30828080
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

These findings suggest that noni fruit has both anxiolytic and antidepressant-like activities.Nov 30, 2017

Pubmed Data : Biomed Pharmacother. 2017 Dec ;96:944-952. Epub 2017 Dec 6. PMID: 29217165
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]

These results may point to noni fruit as an important source of anti-inflammatory molecules.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mediators Inflamm. 2017 ;2017:6567432. Epub 2017 Jan 17. PMID: 28194046
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Colitis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-17 downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

This study provides a basis for noni fruit polysaccharidesas a cheap intervention for the prevention and treatment of IBD patients.Aug 24, 2021

Pubmed Data : J Agric Food Chem. 2021 Aug 25. Epub 2021 Aug 25. PMID: 34432454
Article Published Date : Aug 24, 2021
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Polysaccharides
[+]

Treatment with Morinda citrifolia leaf extract resulted in significant improvement in the metabolic perturbations caused obesity.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Diabetes Res. 2016 ;2016:2391592. Epub 2015 Dec 20. PMID: 26798649
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : High Fat Diet, Obesity
Additional Keywords : Anti-Obesity Agents, Plant Extracts
[+]

"Damnacanthal, a noni component, exhibits antitumorigenic activity in human colorectal cancer cells."Aug 16, 2011

Pubmed Data : J Nutr Biochem. 2011 Aug 16. Epub 2011 Aug 16. PMID: 21852088
Article Published Date : Aug 16, 2011
Study Type : In Vitro Study
Additional Links
Substances : Damnacanthal, Noni
Diseases : Colorectal Cancer
Pharmacological Actions : Anti-Inflammatory Agents
[+]

A compound in noni exhibits anti-cancer activity in liver cancer cell ines.Oct 14, 2010

Pubmed Data : Eur J Pharmacol. 2010 Oct 14. Epub 2010 Oct 14. PMID: 20951126
Article Published Date : Oct 14, 2010
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Anthraquinones with potential antiproliferative activities from the fruits of Morinda citrifolia.Dec 12, 2021

Pubmed Data : Nat Prod Res. 2021 Dec 13:1-7. Epub 2021 Dec 13. PMID: 34894893
Article Published Date : Dec 12, 2021
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Breast Cancer, Colon Cancer, Liver Cancer, Lung Cancer, Promyelocytic leukemia
Pharmacological Actions : Antiproliferative
[+]

Anti-inflammatory effects of Morinda citrifolia extract against lipopolysaccharide-induced inflammation in RAW264 cells.Aug 03, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicines (Basel). 2021 Aug 4 ;8(8). Epub 2021 Aug 4. PMID: 34436222
Article Published Date : Aug 03, 2021
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor
[+]

Antibacterial activity of the noni fruit extract against Listeria monocytogenes and its applicability as a natural sanitizer for the washing of fresh-cut produce.Nov 30, 2019

Pubmed Data : Food Microbiol. 2019 Dec ;84:103260. Epub 2019 Jul 5. PMID: 31421758
Article Published Date : Nov 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Foodborne Pathogens: Prevention/Food Preservation, Listeria Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Plant Extracts
[+]

Chrysin combined with apigenin can reduce HepG2 and MDA-MB-231 proliferation, cell motility and induce apoptosis.May 02, 2016

Pubmed Data : J Agric Food Chem. 2016 May 3. Epub 2016 May 3. PMID: 27137679
Article Published Date : May 02, 2016
Study Type : In Vitro Study
Additional Links
Substances : Apigenin, Chrysin, Noni
Diseases : Breast Cancer, Breast Cancer: Triple Negative , Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Natural Substance Synergy, Plant Extracts
[+]

Compounds from noni have potential for used as anti tumor agents for oral cancer therapy.Dec 28, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2017 Dec 29 ;18(12):3333-3341. Epub 2017 Dec 29. PMID: 29286228
Article Published Date : Dec 28, 2017
Study Type : In Vitro Study
Additional Links
Substances : Damnacanthal, Noni
Diseases : Oral Cancer, Squamous cell carcinoma
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Plant Extracts
[+]

Costa Rican noni juice exhibits anti-oxidative and anti-inflammatory properties.Sep 19, 2010

Pubmed Data : J Ethnopharmacol. 2010 Sep 19. Epub 2010 Sep 19. PMID: 20858541
Article Published Date : Sep 19, 2010
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Efficacy and safety of Morinda citrifolia as a potential anticancer agent.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Cancer Ther. 2022 ;21:15347354221132848. PMID: 36448674
Article Published Date : Dec 31, 2021
Study Type : Review
Additional Links
Substances : Noni
Diseases : Cancers: All
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Immunomodulatory
[+]

Enhanced anti-cancer activity of chitosan loaded Morinda citrifolia essential oil against A549 human lung cancer cells.Nov 30, 2020

Pubmed Data : Int J Biol Macromol. 2020 Dec 1 ;164:4010-4021. Epub 2020 Aug 24. PMID: 32853609
Article Published Date : Nov 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Lung Cancer
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Essential Oils
[+]

Extracts of Neem, Noni and Aloe vera showed inhibitory effects against E. faecalis.Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Int Soc Prev Community Dent. 2016 May-Jun;6(3):196-9. Epub 2016 May 30. PMID: 27382533
Article Published Date : Apr 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Aloe Vera, Neem, Noni
Diseases : Gram-Positive Bacterial Infections
Pharmacological Actions : Antimicrobial
Additional Keywords : Plant Extracts
[+]

Identification of anti-inflammatory compounds from Hawaiian noni. Oct 26, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Oct 27 ;25(21). Epub 2020 Oct 27. PMID: 33121016
Article Published Date : Oct 26, 2020
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Immunomodulatory actions of a polynesian herb noni.Nov 30, 2019

Pubmed Data : Complement Ther Med. 2019 Dec ;47:102206. Epub 2019 Oct 3. PMID: 31780035
Article Published Date : Nov 30, 2019
Study Type : Review
Additional Links
Substances : Noni
Pharmacological Actions : Antioxidants, Immunomodulatory
Additional Keywords : Plant Extracts
[+]

M. citrifolia fruit juice exhibited antileishmanial activity against L. amazonensis axenic amastigotes.Jul 17, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Res Notes. 2018 Jul 18 ;11(1):492. Epub 2018 Jul 18. PMID: 30021621
Article Published Date : Jul 17, 2018
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Leishmaniasis
Pharmacological Actions : Leishmanicidal
[+]

M. citrifolia leaf extract suppressed inflammation, and potential metastasis by inhibiting new cancer-related blood vessel formation.Jun 30, 2019

Pubmed Data : J Food Biochem. 2019 Jul ;43(7):e12868. Epub 2019 Apr 24. PMID: 31353737
Article Published Date : Jun 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Leukemia
Pharmacological Actions : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Antiproliferative , Apoptotic, Interleukin-10 upregulation, Interleukin-4 upregulation
[+]

Morinda citrifolia and turmeric extracts have antibacterial activity against E. faecalis.Sep 30, 2016

Pubmed Data : J Clin Diagn Res. 2016 Oct ;10(10):ZC55-ZC57. Epub 2016 Oct 1. PMID: 27891459
Article Published Date : Sep 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Noni, Turmeric
Diseases : Enterococcus Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Plant Extracts
[+]

Morinda citrifolia may be an alternative therapeutic resource with great potential in the treatment of obesity and obesity-related metabolic dysfunction.May 24, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 May 25 ;9(6). Epub 2017 May 25. PMID: 28587078
Article Published Date : May 24, 2017
Study Type : Review
Additional Links
Substances : Noni
Diseases : Metabolic Diseases, Obesity
Additional Keywords : Anti-Obesity Agents
[+]

N-butanol extracts of Morinda citrifolia suppress advanced glycation end products induced inflammatory reactions in endothelial cells.Mar 03, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2017 Mar 4 ;17(1):137. Epub 2017 Mar 4. PMID: 28259164
Article Published Date : Mar 03, 2017
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Advanced Glycation End products (AGE)
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Noni (M. citrifolia) fruit extract has an antifungal effect on Candida albicans Sep 01, 2009

Pubmed Data : Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Sep;108(3):394-8. PMID: 19716507
Article Published Date : Sep 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Candida Infection
Pharmacological Actions : Antifungal Agents
Additional Keywords : Plant Extracts
[+]

Noni and Wrightia tinctoria exhibit anti-Hepatitis C virus activity.Nov 01, 2009

Pubmed Data : Indian J Pharm Sci. 2009 Nov;71(6):670-2. PMID: 20376221
Article Published Date : Nov 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Noni, Wrightia tinctoria
Diseases : Hepatitis C
Pharmacological Actions : Antiviral Agents
[+]

Noni contains an anthraquinone with potent quinone reductase-inducing (i.e. detoxifying) activity 40 times more potent than sufloraphane.Dec 01, 2010

Pubmed Data : Rejuvenation Res. 2010 Dec;13(6):749-54. PMID: 16378361
Article Published Date : Dec 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Noni, Sulforaphane
Pharmacological Actions : Anticarcinogenic Agents, Quinone Reductase-Inducer
[+]

Noni could enhance the expression of DNA repair genes by itself and in combination with cisplatin.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2015 ;16(8):3457-61. PMID: 25921162
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : DNA damage
Pharmacological Actions : DNA Repair Up-regulation
[+]

Noni demonstrates antitubercular activity.Nov 01, 2002

Pubmed Data : Phytother Res. 2002 Nov;16(7):683-5. PMID: 12410555
Article Published Date : Nov 01, 2002
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Tuberculosis
[+]

Noni exhibits anti-angiogenic activity in human breast tumors.Jan 01, 2003

Pubmed Data : Angiogenesis. 2003;6(2):143-9. PMID: 14739620
Article Published Date : Jan 01, 2003
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Breast Cancer
Pharmacological Actions : Anti-Angiogenic
[+]

Noni exhibits antibacterial activity against Vibrio cholorae.Jun 01, 2004

Pubmed Data : J Med Food. 2004 Summer;7(2):168-79. PMID: 20337116
Article Published Date : Jun 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Cholera, Vibrio Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Plant Extracts
[+]

Noni extracts strongly inhibited the proliferation and increased apoptosis in MCF-7 and MDA-MB-231 cells.Jul 08, 2015

Pubmed Data : Drug Res (Stuttg). 2015 Jul 9. Epub 2015 Jul 9. PMID: 26158795
Article Published Date : Jul 08, 2015
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Plant Extracts
[+]

Noni fruit juice has an inhibitory effect on xanthine oxidase enzymes, supporting the traditional usage of noni in the treatment of gout and gout-like diseases. May 12, 2009

Pubmed Data : Phytother Res. 2009 May 12. PMID: 19434757
Article Published Date : May 12, 2009
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Gout, Pseudogout
Pharmacological Actions : Xanthine oxidase inhibitor
[+]

Noni has selective cytotoxicity against Laryngeal Cancer, Breast Cancer, and Neuroblastoma cell lines. Jun 01, 2006

Pubmed Data : Phytother Res. 2006 Jun;20(6):515-7. PMID: 16619339
Article Published Date : Jun 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Breast Cancer, Laryngeal Cancer, Neuroblastoma
Pharmacological Actions : Antiproliferative
Additional Keywords : Plant Extracts, Selective Cytotoxicity
[+]

Noni has various antioxidant compounds.Apr 01, 2005

Pubmed Data : J Nat Prod. 2005 Apr;68(4):592-5. PMID: 15844957
Article Published Date : Apr 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Noni inhibits Candida albicans and Aspergillus nidulans. Jan 01, 2006

Pubmed Data : Am J Chin Med. 2006;34(3):503-9. PMID: 16710899
Article Published Date : Jan 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Aspergillosis, Candida Infection
[+]

Noni inhibits Epstein-Barr virus early antigen activation. May 01, 2007

Pubmed Data : J Nat Prod. 2007 May;70(5):754-7. Epub 2007 May 5. PMID:17480098
Article Published Date : May 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Epstein-Barr Virus Infections
Pharmacological Actions : Antiviral Agents
[+]

Noni interferes with HIV-1 viral protein's pathogenic effects.Sep 29, 2006

Pubmed Data : Biochem Biophys Res Commun. 2006 Sep 29;348(3):1101-6. Epub 2006 Aug 2. PMID: 16904642
Article Published Date : Sep 29, 2006
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Acquired Immunodeficiency Syndrome
Pharmacological Actions : Antiviral Agents
[+]

Noni juice inhibited the proliferation of A549 lung cancer cells.Jul 08, 2020

Pubmed Data : Chin J Integr Med. 2020 Jul 9. Epub 2020 Jul 9. PMID: 32648127
Article Published Date : Jul 08, 2020
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Lung Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, NF-kappaB Inhibitor
[+]

Noni leaf extract might be a novel alternative medicine for bone and periodontal regeneration in patients with periodontal diseases.Dec 31, 2017

Pubmed Data : J Med Food. 2018 Jan ;21(1):57-69. Epub 2017 Oct 5. PMID: 28981378
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Periodontal Diseases, Wound Healing: Periodontal
Pharmacological Actions : Regenerative, Wnt/β-catenin signaling pathway modulation
Additional Keywords : Bone Regeneration
[+]

Noni leaf possesses antioxidant activities and reduces nociceptive behavior and leukocyte migration.Oct 01, 2011

Pubmed Data : J Med Food. 2011 Oct ;14(10):1159-66. Epub 2011 May 6. PMID: 21548805
Article Published Date : Oct 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Noni leaf extract
Diseases : Inflammation, Oxidative Stress, Pain
Pharmacological Actions : Antioxidants
[+]

Noni may reduce anxiety via affinity with GABA receptors.Aug 01, 2007

Pubmed Data : Phytomedicine. 2007 Aug;14(7-8):517-22. Epub 2007 Jun 11. PMID: 17561385
Article Published Date : Aug 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Anxiety Disorders, Generalized Anxiety Disorder
Pharmacological Actions : Anxiolytic, GABA Modulators
[+]

Phytochemicals naturally synthesized by M. citrifolia have an inhibitory effect on oral streptococci.Oct 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Dent (Tehran). 2014 Nov ;11(6):703-10. Epub 2014 Nov 30. PMID: 25628701
Article Published Date : Oct 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Dental Caries, Streptococcus Infections
Pharmacological Actions : Anti-Bacterial Agents
[+]

Ripe and unripe Noni fruits have strong antiproliferative effects against human liposarcoma SW872 cells.Jun 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Complement Med. 2016 Jul ;6(3):299-304. Epub 2015 Nov 19. PMID: 27419097
Article Published Date : Jun 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Liposarcoma
Pharmacological Actions : Antioxidants, Antiproliferative
Additional Keywords : Plant Extracts
[+]

Scopoletin could be a potential treatment Parkinson's disease.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2019 ;2019:2761041. Epub 2019 May 2. PMID: 31191797
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

The fermented noni fruit promoted probiotic growths and downregulated the intracellular oxidation and inflammation in Caco-2 cells.Feb 03, 2015

Pubmed Data : J Med Food. 2015 Feb 4. Epub 2015 Feb 4. PMID: 25651187
Article Published Date : Feb 03, 2015
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages, Noni, Quercetin
Diseases : Gastrointestinal Inflammation, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-8 downregulation
Additional Keywords : Probiotic
[+]

This review summarizes the human clinical studies using berries or other natural products for chemoprevention of pancreatic ductal adenocarcinoma.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Berry Res. 2017 ;7(3):147-161. Epub 2017 Aug 18. PMID: 29367867
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Substances : Acai, Banana, Berries: All, Black Raspberry, Blackberries, Blueberry, Cranberry, Cucumber, Eggplant, Elderberry, Goji, Grapes, Indian Gooseberry, Kiwifruit, Noni, Raspberry, Tomato, Watermelon
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemopreventive

Copyright: /profile_kamonrat / 123RF Stock Photo

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