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12 Diseases Researched for Okra
NameACCKFocus
Alcohol Toxicity 12Locked
Chemically-Induced Liver Damage12Locked
Diabetes Mellitus: Type 212Locked
Diabetes: Oxidative Stress12Locked
Diabetic Complications12Locked
Fatigue12Locked
Breast Cancer11Locked
Diabetic Nephropathy11Locked
Helicobacter Pylori Infection11Locked
Melanoma11Locked
Neurodegenerative Diseases11Locked
Oxidative Stress11Locked
14 Pharmacological Actions Researched for Okra
NameACCKFocus
Antioxidants47Locked
Anti-Inflammatory Agents12Locked
Apoptotic22Locked
Gastroprotective12Locked
Hepatoprotective12Locked
Immunomodulatory12Locked
Malondialdehyde Down-regulation12Locked
Superoxide Dismutase Up-regulation12Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor12Locked
Alpha-amylase inhibitor11Locked
Antineoplastic Agents11Locked
Antiproliferative 11Locked
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor11Locked
Renoprotective11Locked

View the Evidence:
37 Abstracts with Okra Research

[+]

A systematic review and meta-analysis of Abelmoschus manihot for diabetic nephropathy.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:9679234. Epub 2019 Apr 18. PMID: 31118973
Article Published Date : Dec 31, 2018
Study Type : Meta Analysis, Review
Additional Links
Substances : Okra
Diseases : Diabetic Nephropathy
Pharmacological Actions : Renoprotective
[+]

A manihot is a promising therapy for patients with primary kidney disease.Jun 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Kidney Dis. 2014 Jul ;64(1):57-65. Epub 2014 Mar 14. PMID: 24631042
Article Published Date : Jun 30, 2014
Study Type : Human Study
Additional Links
Substances : Okra
Diseases : Chronic Kidney Disease (CKD), Proteinuria
Pharmacological Actions : Renoprotective
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Okra consumption can elicit improvements in lipid profile, as well as glycemic markers, among T2D patients.Jul 23, 2020

Pubmed Data : Phytother Res. 2020 Jul 24. Epub 2020 Jul 24. PMID: 32706159
Article Published Date : Jul 23, 2020
Study Type : Human Study
Additional Links
Substances : Okra
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
[+]

A. esculentus flowers protects against transient cerebral ischemia-reperfusion injury.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:8987173. Epub 2018 Aug 5. PMID: 30174782
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Okra
Diseases : Brain Ischemia, Cerebral Ischemia
Pharmacological Actions : Antioxidants, Heme oxygenase-1 inducer, Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Nrf2 activation
[+]

Abelmoschus esculentus peel powder improves high-fat-diet-induced cognitive impairment.Jul 29, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2020 Jul 30 ;17(15). Epub 2020 Jul 30. PMID: 32751614
Article Published Date : Jul 29, 2020
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Cognitive Decline/Dysfunction, High Fat Diet
Pharmacological Actions : Neuroprotective Agents
[+]

Abelmoschus esculentus subfractions improved nephropathy with regulating dipeptidyl peptidase-4 and type 1 glucagon-like peptide receptor.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Food Drug Anal. 2019 Jan ;27(1):135-144. Epub 2018 Aug 14. PMID: 30648566
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Diabetes Mellitus: Type 2, Diabetic Nephropathy
Pharmacological Actions : Antioxidants, Renoprotective
[+]

Antidepressant activity of flavonoid ethanol extract of Abelmoschus manihot corolla with BDNF up-regulation in the hippocampus.Jan 31, 2017

Pubmed Data : Yao Xue Xue Bao. 2017 Feb ;52(2):222-8. PMID: 29979503
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Isoquercitrin, Okra, Quercetin
Diseases : Depression
Pharmacological Actions : Antidepressive Agents, Brain-derived neurotrophic factor modulator
Additional Keywords : Plant Extracts
[+]

Flos Abelmoschus manihot extract attenuates DSS-induced colitis by regulating gut microbiota and Th17/Treg balance.Aug 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Sep ;117:109162. Epub 2019 Jun 26. PMID: 31254739
Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Colitis
Pharmacological Actions : Gastrointestinal Agents, Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Okra could be a possible therapeutic antiulcer agent.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2018 Dec ;56(1):165-175. PMID: 29513129
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Alcohol Toxicity , Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents
Additional Keywords : Plant Extracts
[+]

Okra lectin has a gastro-protective effect on gastropathy induced by ethanol.Jan 31, 2016

Pubmed Data : Curr Pharm Des. 2016 Feb 1. Epub 2016 Feb 1. PMID: 26831461
Article Published Date : Jan 31, 2016
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Alcohol Toxicity
Pharmacological Actions : Gastroprotective
[+]

Okra may be used as a dietary supplementation in diabetes for prevention of oxidative stress-mediated complications.Oct 31, 2016

Pubmed Data : J Diet Suppl. 2016 Nov ;13(6):634-46. Epub 2016 Apr 11. PMID: 27065051
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Diabetes: Oxidative Stress, Diabetes Mellitus: Type 2, Diabetic Complications
Pharmacological Actions : Antioxidants
[+]

Okra polysaccharide possesses hypoglycemic activity.May 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 May 17 ;24(10). Epub 2019 May 17. PMID: 31108940
Article Published Date : May 16, 2019
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Diabetes: Oxidative Stress, Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Heme oxygenase-1 inducer, Hypoglycemic Agents, Malondialdehyde Down-regulation, Nrf2 activation, Superoxide Dismutase Up-regulation
Additional Keywords : Polysaccharides
[+]

Okra polysaccharides could act as an effective material to enhance immune response.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Pharmacol Sci. 2018 ;2018:8505383. Epub 2018 Oct 9. PMID: 30402093
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Staphylococcus aureus infection
Pharmacological Actions : Immunostimulatory, Interleukin-17 downregulation
Additional Keywords : Polysaccharides
[+]

Okra polysaccharides may potentially serve as novel immunomodulators.Feb 29, 2016

Pubmed Data : J Med Food. 2016 Mar ;19(3):253-65. Epub 2016 Feb 2. PMID: 26836029
Article Published Date : Feb 29, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Okra
Pharmacological Actions : Immunomodulatory
[+]

Okra powder could be useful intervention for improvement of ovaian dysfunction in diabetes.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Pharm Res. 2019 ;18(1):369-382. PMID: 31089371
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Diabetes: Oxidative Stress, Diabetic Complications, High Fat Diet
Pharmacological Actions : Anti-Apoptotic, Antioxidants
Additional Keywords : Gene Expression Regulation
[+]

Okra seeds possessed significant antioxidant and anti-fatigue effects.Sep 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2015 Oct ;7(10):8846-58. Epub 2015 Oct 26. PMID: 26516905
Article Published Date : Sep 30, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Okra
Diseases : Fatigue
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
[+]

Purification, characterization and anti-fatigue activity of polysaccharide fractions from okra.Feb 20, 2018

Pubmed Data : Food Funct. 2018 Feb 21 ;9(2):1088-1101. PMID: 29359209
Article Published Date : Feb 20, 2018
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Fatigue
Additional Keywords : Plant Extracts, Polysaccharides
[+]

Supplementation of Abelmoschus manihot ameliorates diabetic nephropathy and hepatic steatosis.Nov 06, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Nov 7 ;10(11). Epub 2018 Nov 7. PMID: 30405076
Article Published Date : Nov 06, 2018
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Diabetic Nephropathy, Hepatic Steatosis
Pharmacological Actions : Autophagy Up-regulation, Hepatoprotective, Renoprotective
Additional Keywords : Plant Extracts
[+]

The nutraceutical benefits of subfractions of Abelmoschus esculentus in treating type 2 diabetes mellitus.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(12):e0189065. Epub 2017 Dec 7. PMID: 29216237
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Diabetes Mellitus: Type 2, Dyslipidemias
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
Additional Keywords : Plant Extracts
[+]

These results substantiated the hepatoprotective activity of A. esculentus through its antioxidant capacity.Aug 31, 2013

Pubmed Data : Toxicol Mech Methods. 2013 Sep ;23(7):528-36. Epub 2013 May 17. PMID: 23581558
Article Published Date : Aug 31, 2013
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Dose Response, Plant Extracts
[+]

These results suggested that okra polysaccharide ameliorated diabetic nephropathy in diabetic mice.Aug 19, 2019

Pubmed Data : Int J Biol Macromol. 2019 Aug 20 ;140:568-576. Epub 2019 Aug 20. PMID: 31442509
Article Published Date : Aug 19, 2019
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Diabetes Mellitus: Type 2, Diabetic Nephropathy
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Renoprotective
Additional Keywords : Polysaccharides
[+]

Total extracts of Abelmoschus manihot attenuates adriamycin-induced renal tubule injury.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:567. Epub 2019 May 28. PMID: 31191310
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin, Nephropathy
Pharmacological Actions : Chemoprotective Agents, Renoprotective
[+]

Total flavone of Abelmoschus manihot ameliorates Crohn's disease by regulating the NF‑κB and MAPK signaling pathways.Jun 30, 2019

Pubmed Data : Int J Mol Med. 2019 Jul ;44(1):324-334. Epub 2019 May 6. PMID: 31059072
Article Published Date : Jun 30, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Okra
Diseases : Crohn's Disease
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Abscisic acid identification in Okra, Abelmoschus esculentus L. (Moench): perspective nutraceutical use for the treatment of diabetes.Jul 07, 2019

Pubmed Data : Nat Prod Res. 2019 Jul 8:1-7. Epub 2019 Jul 8. PMID: 31282220
Article Published Date : Jul 07, 2019
Study Type : In Vitro Study
Additional Links
Substances : Okra
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
[+]

Compounds found within Okra inhibit Helicobacter pylori to human gastric mucosa.Mar 24, 2004

Pubmed Data : J Agric Food Chem. 2004 Mar 24;52(6):1495-503. PMID: 15030201
Article Published Date : Mar 24, 2004
Study Type : In Vitro Study
Additional Links
Substances : Okra
Diseases : Helicobacter Pylori Infection
[+]

Flavonoids derived from Abelmoschus esculentus attenuates UV-B induced cell damage.Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacogn Mag. 2016 May ;12(Suppl 2):S129-38. Epub 2016 May 11. PMID: 27279697
Article Published Date : Apr 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Okra
Diseases : Ultraviolet Radiation Induced Damage
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation, Photoprotective
[+]

Flos A. manihot was more effective than the angiotensin-receptor blocker losartan in reducing proteinuria in patients with primary glomerular disease.Jan 31, 2016

Pubmed Data : Clin Exp Pharmacol Physiol. 2016 Feb ;43(2):145-8. PMID: 26667396
Article Published Date : Jan 31, 2016
Study Type : Review
Additional Links
Substances : Okra
Diseases : Chronic Kidney Disease (CKD), Proteinuria
Pharmacological Actions : Anti-Apoptotic, Renoprotective, Transforming growth factor beta (TGF-β) inhibitor
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Lectin from Okra promotes selective antitumor effects in human breast cancer cells.Feb 28, 2014

Pubmed Data : Biotechnol Lett. 2014 Mar ;36(3):461-9. Epub 2013 Oct 16. PMID: 24129958
Article Published Date : Feb 28, 2014
Study Type : In Vitro Study
Additional Links
Substances : Okra
Diseases : Breast Cancer
Pharmacological Actions : Antineoplastic Agents, Apoptotic
Additional Keywords : Lectins, Selective Cytotoxicity
[+]

Okra could be an adjuvant to protect neuron degenerative disease related to Aβ and insulin resistance.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2019 ;14(6):e0217400. Epub 2019 Jun 25. PMID: 31237881
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Okra
[+]

Okra extract has a hypoglycemic effect that helps decrease blood glucose level.Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Med Sci. 2016 May ;41(3 Suppl):S63. PMID: 27840529
Article Published Date : Apr 30, 2016
Study Type : Review
Additional Links
Substances : Okra
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
[+]

Okra has the potential to serve as an adjuvant for diabetic nephropathy.Feb 16, 2016

Pubmed Data : Food Funct. 2016 Feb 17 ;7(2):728-40. PMID: 26787242
Article Published Date : Feb 16, 2016
Study Type : In Vitro Study
Additional Links
Substances : Okra
Diseases : Diabetic Nephropathy
Pharmacological Actions : Renoprotective
[+]

Okra has three potential α-amylase inhibitors.Sep 02, 2015

Pubmed Data : J Sep Sci. 2015 Sep 3. Epub 2015 Sep 3. PMID: 26337511
Article Published Date : Sep 02, 2015
Study Type : In Vitro Study
Additional Links
Substances : Okra
Pharmacological Actions : Alpha-amylase inhibitor
[+]

Okra may be beneficial in people expressing the H63D variant to reduce the risk of AD and other neurodegenerative diseases.Aug 30, 2015

Pubmed Data : Neurosci Lett. 2015 Aug 31 ;603:6-11. Epub 2015 Jul 10. PMID: 26170247
Article Published Date : Aug 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Okra
Diseases : Neurodegenerative Diseases, Oxidative Stress
Pharmacological Actions : Antioxidants, Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor
Additional Keywords : Plant Extracts
[+]

Okra pectin is antiproliferative and induces programmed cell death in melanoma cells. Dec 09, 2009

Pubmed Data : Phytother Res. 2009 Dec 9. PMID: 20013817
Article Published Date : Dec 09, 2009
Study Type : In Vitro Study
Additional Links
Substances : Okra
Diseases : Melanoma
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

The effect of okra seed extract on human cancer cell lines delivered in its native form and loaded in polymeric micelles.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Biomater. 2019 ;2019:9404383. Epub 2019 Oct 21. PMID: 31781223
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Okra
Diseases : Breast Cancer, Cervical Cancer, Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

These results demonstrated that okra pod mucilage had potential sources of natural antioxidant.Apr 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2018 May ;6(3):563-571. Epub 2018 Feb 2. PMID: 29876107
Article Published Date : Apr 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Okra
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Total flavone of Abelmoschus manihot is expected to advance as a new therapy to treat Crohn's disease intestinal fibrosis.Aug 13, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2018 Aug 14 ;24(30):3414-3425. PMID: 30122880
Article Published Date : Aug 13, 2018
Study Type : In Vitro Study
Additional Links
Substances : Okra
Diseases : Crohn's Disease, Fibrosis
Pharmacological Actions : Anti-Fibrotic, Transforming growth factor beta (TGF-β) inhibitor
Additional Keywords : Plant Extracts

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