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31 Diseases Researched for Okra
NameACCKFocus
Diabetic Nephropathy527Locked
Diabetes Mellitus: Type 2822Locked
Chronic Kidney Disease (CKD)211Locked
Proteinuria211Locked
Diabetes: Oxidative Stress36Locked
Alcohol Toxicity 24Locked
Diabetic Complications24Locked
Fatigue24Locked
High Fat Diet24Locked
Crohn's Disease23Locked
Brain Ischemia12Locked
Breast Cancer22Locked
Cerebral Ischemia12Locked
Chemically-Induced Liver Damage12Locked
Chemotherapy-Induced Toxicity: Doxorubicin12Locked
Cognitive Decline/Dysfunction12Locked
Colitis12Locked
Depression12Locked
Dyslipidemias12Locked
Gastric Ulcer12Locked
Hepatic Steatosis12Locked
Nephropathy12Locked
Oxidative Stress22Locked
Staphylococcus aureus infection12Locked
Cervical Cancer11Locked
Fibrosis11Locked
Helicobacter Pylori Infection11Locked
Liver Cancer11Locked
Melanoma11Locked
Neurodegenerative Diseases11Locked
Ultraviolet Radiation Induced Damage11Locked
35 Pharmacological Actions Researched for Okra
NameACCKFocus
Renoprotective840Locked
Antioxidants1119Locked
Hypoglycemic Agents516Locked
Hypolipidemic313Locked
Malondialdehyde Down-regulation36Locked
Anti-Apoptotic35Locked
Nrf2 activation35Locked
Anti-Inflammatory Agents24Locked
Heme oxygenase-1 inducer24Locked
Hepatoprotective24Locked
Immunomodulatory24Locked
Neuroprotective Agents24Locked
Superoxide Dismutase Up-regulation24Locked
Apoptotic33Locked
Anti-Ulcer Agents12Locked
Antidepressive Agents12Locked
Antiproliferative 22Locked
Autophagy Up-regulation12Locked
Brain-derived neurotrophic factor modulator12Locked
Chemoprotective Agents12Locked
Gastrointestinal Agents12Locked
Gastroprotective12Locked
Immunomodulatory: Th17 downregulation12Locked
Immunostimulatory12Locked
Interleukin-17 downregulation12Locked
NF-kappaB Inhibitor12Locked
Nitric Oxide Inhibitor12Locked
Transforming growth factor beta (TGF-β) inhibitor22Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor12Locked
Alpha-amylase inhibitor11Locked
Anti-Fibrotic11Locked
Antineoplastic Agents11Locked
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor11Locked
Heme oxygenase-1 up-regulation11Locked
Photoprotective11Locked

View the Evidence:
37 Abstracts with Okra Research

[+]

A systematic review and meta-analysis of Abelmoschus manihot for diabetic nephropathy.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:9679234. Epub 2019 Apr 18. PMID: 31118973
Article Published Date : Dec 31, 2018
Study Type : Meta Analysis, Review
Additional Links
Substances : Okra
Diseases : Diabetic Nephropathy
Pharmacological Actions : Renoprotective
[+]

A manihot is a promising therapy for patients with primary kidney disease.Jun 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Kidney Dis. 2014 Jul ;64(1):57-65. Epub 2014 Mar 14. PMID: 24631042
Article Published Date : Jun 30, 2014
Study Type : Human Study
Additional Links
Substances : Okra
Diseases : Chronic Kidney Disease (CKD), Proteinuria
Pharmacological Actions : Renoprotective
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Okra consumption can elicit improvements in lipid profile, as well as glycemic markers, among T2D patients.Jul 23, 2020

Pubmed Data : Phytother Res. 2020 Jul 24. Epub 2020 Jul 24. PMID: 32706159
Article Published Date : Jul 23, 2020
Study Type : Human Study
Additional Links
Substances : Okra
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
[+]

A. esculentus flowers protects against transient cerebral ischemia-reperfusion injury.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:8987173. Epub 2018 Aug 5. PMID: 30174782
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Okra
Diseases : Brain Ischemia, Cerebral Ischemia
Pharmacological Actions : Antioxidants, Heme oxygenase-1 inducer, Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Nrf2 activation
[+]

Abelmoschus esculentus peel powder improves high-fat-diet-induced cognitive impairment.Jul 29, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2020 Jul 30 ;17(15). Epub 2020 Jul 30. PMID: 32751614
Article Published Date : Jul 29, 2020
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Cognitive Decline/Dysfunction, High Fat Diet
Pharmacological Actions : Neuroprotective Agents
[+]

Abelmoschus esculentus subfractions improved nephropathy with regulating dipeptidyl peptidase-4 and type 1 glucagon-like peptide receptor.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Food Drug Anal. 2019 Jan ;27(1):135-144. Epub 2018 Aug 14. PMID: 30648566
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Diabetes Mellitus: Type 2, Diabetic Nephropathy
Pharmacological Actions : Antioxidants, Renoprotective
[+]

Antidepressant activity of flavonoid ethanol extract of Abelmoschus manihot corolla with BDNF up-regulation in the hippocampus.Jan 31, 2017

Pubmed Data : Yao Xue Xue Bao. 2017 Feb ;52(2):222-8. PMID: 29979503
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Isoquercitrin, Okra, Quercetin
Diseases : Depression
Pharmacological Actions : Antidepressive Agents, Brain-derived neurotrophic factor modulator
Additional Keywords : Plant Extracts
[+]

Flos Abelmoschus manihot extract attenuates DSS-induced colitis by regulating gut microbiota and Th17/Treg balance.Aug 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Sep ;117:109162. Epub 2019 Jun 26. PMID: 31254739
Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Colitis
Pharmacological Actions : Gastrointestinal Agents, Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Okra could be a possible therapeutic antiulcer agent.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2018 Dec ;56(1):165-175. PMID: 29513129
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Alcohol Toxicity , Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents
Additional Keywords : Plant Extracts
[+]

Okra lectin has a gastro-protective effect on gastropathy induced by ethanol.Jan 31, 2016

Pubmed Data : Curr Pharm Des. 2016 Feb 1. Epub 2016 Feb 1. PMID: 26831461
Article Published Date : Jan 31, 2016
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Alcohol Toxicity
Pharmacological Actions : Gastroprotective
[+]

Okra may be used as a dietary supplementation in diabetes for prevention of oxidative stress-mediated complications.Oct 31, 2016

Pubmed Data : J Diet Suppl. 2016 Nov ;13(6):634-46. Epub 2016 Apr 11. PMID: 27065051
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Diabetes: Oxidative Stress, Diabetes Mellitus: Type 2, Diabetic Complications
Pharmacological Actions : Antioxidants
[+]

Okra polysaccharide possesses hypoglycemic activity.May 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 May 17 ;24(10). Epub 2019 May 17. PMID: 31108940
Article Published Date : May 16, 2019
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Diabetes: Oxidative Stress, Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Heme oxygenase-1 inducer, Hypoglycemic Agents, Malondialdehyde Down-regulation, Nrf2 activation, Superoxide Dismutase Up-regulation
Additional Keywords : Polysaccharides
[+]

Okra polysaccharides could act as an effective material to enhance immune response.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Pharmacol Sci. 2018 ;2018:8505383. Epub 2018 Oct 9. PMID: 30402093
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Staphylococcus aureus infection
Pharmacological Actions : Immunostimulatory, Interleukin-17 downregulation
Additional Keywords : Polysaccharides
[+]

Okra polysaccharides may potentially serve as novel immunomodulators.Feb 29, 2016

Pubmed Data : J Med Food. 2016 Mar ;19(3):253-65. Epub 2016 Feb 2. PMID: 26836029
Article Published Date : Feb 29, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Okra
Pharmacological Actions : Immunomodulatory
[+]

Okra powder could be useful intervention for improvement of ovaian dysfunction in diabetes.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Pharm Res. 2019 ;18(1):369-382. PMID: 31089371
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Diabetes: Oxidative Stress, Diabetic Complications, High Fat Diet
Pharmacological Actions : Anti-Apoptotic, Antioxidants
Additional Keywords : Gene Expression Regulation
[+]

Okra seeds possessed significant antioxidant and anti-fatigue effects.Sep 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2015 Oct ;7(10):8846-58. Epub 2015 Oct 26. PMID: 26516905
Article Published Date : Sep 30, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Okra
Diseases : Fatigue
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
[+]

Purification, characterization and anti-fatigue activity of polysaccharide fractions from okra.Feb 20, 2018

Pubmed Data : Food Funct. 2018 Feb 21 ;9(2):1088-1101. PMID: 29359209
Article Published Date : Feb 20, 2018
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Fatigue
Additional Keywords : Plant Extracts, Polysaccharides
[+]

Supplementation of Abelmoschus manihot ameliorates diabetic nephropathy and hepatic steatosis.Nov 06, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Nov 7 ;10(11). Epub 2018 Nov 7. PMID: 30405076
Article Published Date : Nov 06, 2018
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Diabetic Nephropathy, Hepatic Steatosis
Pharmacological Actions : Autophagy Up-regulation, Hepatoprotective, Renoprotective
Additional Keywords : Plant Extracts
[+]

The nutraceutical benefits of subfractions of Abelmoschus esculentus in treating type 2 diabetes mellitus.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(12):e0189065. Epub 2017 Dec 7. PMID: 29216237
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Diabetes Mellitus: Type 2, Dyslipidemias
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
Additional Keywords : Plant Extracts
[+]

These results substantiated the hepatoprotective activity of A. esculentus through its antioxidant capacity.Aug 31, 2013

Pubmed Data : Toxicol Mech Methods. 2013 Sep ;23(7):528-36. Epub 2013 May 17. PMID: 23581558
Article Published Date : Aug 31, 2013
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Dose Response, Plant Extracts
[+]

These results suggested that okra polysaccharide ameliorated diabetic nephropathy in diabetic mice.Aug 19, 2019

Pubmed Data : Int J Biol Macromol. 2019 Aug 20 ;140:568-576. Epub 2019 Aug 20. PMID: 31442509
Article Published Date : Aug 19, 2019
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Diabetes Mellitus: Type 2, Diabetic Nephropathy
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Renoprotective
Additional Keywords : Polysaccharides
[+]

Total extracts of Abelmoschus manihot attenuates adriamycin-induced renal tubule injury.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:567. Epub 2019 May 28. PMID: 31191310
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin, Nephropathy
Pharmacological Actions : Chemoprotective Agents, Renoprotective
[+]

Total flavone of Abelmoschus manihot ameliorates Crohn's disease by regulating the NF‑κB and MAPK signaling pathways.Jun 30, 2019

Pubmed Data : Int J Mol Med. 2019 Jul ;44(1):324-334. Epub 2019 May 6. PMID: 31059072
Article Published Date : Jun 30, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Okra
Diseases : Crohn's Disease
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Abscisic acid identification in Okra, Abelmoschus esculentus L. (Moench): perspective nutraceutical use for the treatment of diabetes.Jul 07, 2019

Pubmed Data : Nat Prod Res. 2019 Jul 8:1-7. Epub 2019 Jul 8. PMID: 31282220
Article Published Date : Jul 07, 2019
Study Type : In Vitro Study
Additional Links
Substances : Okra
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
[+]

Compounds found within Okra inhibit Helicobacter pylori to human gastric mucosa.Mar 24, 2004

Pubmed Data : J Agric Food Chem. 2004 Mar 24;52(6):1495-503. PMID: 15030201
Article Published Date : Mar 24, 2004
Study Type : In Vitro Study
Additional Links
Substances : Okra
Diseases : Helicobacter Pylori Infection
[+]

Flavonoids derived from Abelmoschus esculentus attenuates UV-B induced cell damage.Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacogn Mag. 2016 May ;12(Suppl 2):S129-38. Epub 2016 May 11. PMID: 27279697
Article Published Date : Apr 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Okra
Diseases : Ultraviolet Radiation Induced Damage
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation, Photoprotective
[+]

Flos A. manihot was more effective than the angiotensin-receptor blocker losartan in reducing proteinuria in patients with primary glomerular disease.Jan 31, 2016

Pubmed Data : Clin Exp Pharmacol Physiol. 2016 Feb ;43(2):145-8. PMID: 26667396
Article Published Date : Jan 31, 2016
Study Type : Review
Additional Links
Substances : Okra
Diseases : Chronic Kidney Disease (CKD), Proteinuria
Pharmacological Actions : Anti-Apoptotic, Renoprotective, Transforming growth factor beta (TGF-β) inhibitor
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Lectin from Okra promotes selective antitumor effects in human breast cancer cells.Feb 28, 2014

Pubmed Data : Biotechnol Lett. 2014 Mar ;36(3):461-9. Epub 2013 Oct 16. PMID: 24129958
Article Published Date : Feb 28, 2014
Study Type : In Vitro Study
Additional Links
Substances : Okra
Diseases : Breast Cancer
Pharmacological Actions : Antineoplastic Agents, Apoptotic
Additional Keywords : Lectins, Selective Cytotoxicity
[+]

Okra could be an adjuvant to protect neuron degenerative disease related to Aβ and insulin resistance.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2019 ;14(6):e0217400. Epub 2019 Jun 25. PMID: 31237881
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Okra
[+]

Okra extract has a hypoglycemic effect that helps decrease blood glucose level.Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Med Sci. 2016 May ;41(3 Suppl):S63. PMID: 27840529
Article Published Date : Apr 30, 2016
Study Type : Review
Additional Links
Substances : Okra
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
[+]

Okra has the potential to serve as an adjuvant for diabetic nephropathy.Feb 16, 2016

Pubmed Data : Food Funct. 2016 Feb 17 ;7(2):728-40. PMID: 26787242
Article Published Date : Feb 16, 2016
Study Type : In Vitro Study
Additional Links
Substances : Okra
Diseases : Diabetic Nephropathy
Pharmacological Actions : Renoprotective
[+]

Okra has three potential α-amylase inhibitors.Sep 02, 2015

Pubmed Data : J Sep Sci. 2015 Sep 3. Epub 2015 Sep 3. PMID: 26337511
Article Published Date : Sep 02, 2015
Study Type : In Vitro Study
Additional Links
Substances : Okra
Pharmacological Actions : Alpha-amylase inhibitor
[+]

Okra may be beneficial in people expressing the H63D variant to reduce the risk of AD and other neurodegenerative diseases.Aug 30, 2015

Pubmed Data : Neurosci Lett. 2015 Aug 31 ;603:6-11. Epub 2015 Jul 10. PMID: 26170247
Article Published Date : Aug 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Okra
Diseases : Neurodegenerative Diseases, Oxidative Stress
Pharmacological Actions : Antioxidants, Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor
Additional Keywords : Plant Extracts
[+]

Okra pectin is antiproliferative and induces programmed cell death in melanoma cells. Dec 09, 2009

Pubmed Data : Phytother Res. 2009 Dec 9. PMID: 20013817
Article Published Date : Dec 09, 2009
Study Type : In Vitro Study
Additional Links
Substances : Okra
Diseases : Melanoma
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

The effect of okra seed extract on human cancer cell lines delivered in its native form and loaded in polymeric micelles.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Biomater. 2019 ;2019:9404383. Epub 2019 Oct 21. PMID: 31781223
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Okra
Diseases : Breast Cancer, Cervical Cancer, Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

These results demonstrated that okra pod mucilage had potential sources of natural antioxidant.Apr 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2018 May ;6(3):563-571. Epub 2018 Feb 2. PMID: 29876107
Article Published Date : Apr 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Okra
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Total flavone of Abelmoschus manihot is expected to advance as a new therapy to treat Crohn's disease intestinal fibrosis.Aug 13, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2018 Aug 14 ;24(30):3414-3425. PMID: 30122880
Article Published Date : Aug 13, 2018
Study Type : In Vitro Study
Additional Links
Substances : Okra
Diseases : Crohn's Disease, Fibrosis
Pharmacological Actions : Anti-Fibrotic, Transforming growth factor beta (TGF-β) inhibitor
Additional Keywords : Plant Extracts

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