Olive

Name	AC	CK
Oxidative Stress	48	132
Cardiovascular Diseases	20	103
Inflammation	44	94
Hypertension	14	84
Breast Cancer	24	47
Insulin Resistance	8	44
Obesity	15	40
Alzheimer's Disease	17	39
Diabetes Mellitus: Type 2	18	39
Lipopolysaccharide-Induced Toxicity	16	35
Nonalcoholic fatty liver disease (NAFLD)	8	32
Upper Respiratory Infections	1	30
Cancers: All	23	29
Myocardial Infarction	5	27
Rheumatoid Arthritis	4	27
Hypercholesterolemia	4	24
Aging	7	22
Arteriosclerosis	7	21
Atherosclerosis	7	21
High Cholesterol	3	21
Breast Cancer: Prevention	2	20
Coronary Artery Disease	2	20
Dyslipidemias	2	20
Ear Infection	2	20
Gastroesophageal Reflux	2	20
Brain Inflammation	11	19
Cholesterol: Oxidation	7	19
Colon Cancer	11	19
Coronavirus Infection	7	18
Hyperglycemia	6	17
Parkinson's Disease	12	17
Chemically-Induced Liver Damage	7	16
DNA damage	7	16
High Fat Diet	8	16
Colitis	9	15
Hyperlipidemia	4	15
Osteoarthritis	5	15
Ulcerative Colitis	4	15
Chemotherapy-Induced Toxicity: Cisplatin	7	14
Multiple Sclerosis	4	14
Coronavirus Disease (Covid-19)	3	13
Gastric Cancer	4	13
HIV Infections	6	13
Metabolic Syndrome X	4	13
Neurodegenerative Diseases	10	13
Clotting	2	12
Lipid Peroxidation	2	12
Ovarian Cancer	3	12
Stroke	3	12
Chronic Kidney Disease (CKD)	2	11
Cognitive Decline/Dysfunction	6	11
Leukemia	2	11
Melanoma	7	11
Aging Skin	1	10
Anal Fissure	1	10
Angina Pectoris	1	10
Blepharitis	1	10
Blood Coagulation Disorders	1	10
Breast Milk: Inadequate/Poor Quality	1	10
C-Reactive Protein	1	10
Candidiasis: Vulvovaginal	1	10
Chronic Lymphocytic Leukemia	1	10
Constipation	1	10
Cystitis	1	10
Dermatitis	1	10
Diaper Rash	1	10
Infant Care	1	10
Meibomian gland dysfunction	1	10
Oral Mucositis	1	10
Otitis media	1	10
Pityriasis Versicolor	1	10
Prediabetes	1	10
Prenatal Nutrition: Health of the Offspring	1	10
Prenatal Nutrition: Prevention of Problems	1	10
Psoriasis	1	10
Raynaud Disease	1	10
Sarcopenia	1	10
Statin-Induced Pathologies	1	10
Stress	1	10
Tinea	1	10
Urinary Tract Infections	1	10
Weight Problems	1	10
Wheezing: Infants	1	10
Chemotherapy-Induced Toxicity: Doxorubicin	5	9
Depression	5	9
Fatty Liver	4	9
Osteoporosis	5	9
Ultraviolet Radiation Induced Damage	4	9
Brain: Oxidative Stress	5	8
Diabetes Mellitus: Type 1	3	8
Endothelial Dysfunction	5	8
Inflammatory Bowel Diseases	5	8
Sepsis	4	8
Skin Diseases: Photo-Aging	3	8
Diabetic Complications	4	7
Fibromyalgia	2	7
Kidney Damage	4	7
Liver Damage	4	7
Myocardial Ischemia	4	7
Bisphenol-A Toxicity	1	6
Chemotherapy-Induced Toxicity	3	6
Diabetes: Cognitive Dysfunction	3	6
Drug-Induced Toxicity: Indomethacin	3	6
Gastric Ulcer	2	6
Glioblastoma	5	6
Ischemia	3	6
Kidney Damage: Chemically-Induced	3	6
Liver Cancer	6	6
Liver Fibrosis	3	6
Liver Steatosis	3	6
Lung Injury: Acute	3	6
Mycobacterium Infections	2	6
Prostate Cancer	4	6
Skin Cancer	2	6
Alcohol Toxicity	3	5
Asthma	2	5
Breast Cancer: Triple Negative	4	5
Hydrogen Peroxide Induced Toxicity	4	5
Leishmaniasis	2	5
Liver Cirrhosis	2	5
Lung Cancer	5	5
Neuropathic Pain	3	5
Staphylococcus aureus infection	5	5
Advanced Glycation End products (AGE)	3	4
Arsenic Poisoning	2	4
Atopic Dermatitis	2	4
Bisphenol Toxicity	1	4
Cardiomyopathy	2	4
Cardiotoxicity: Chemotherapy-Induced	2	4
Cerebral Ischemia	2	4
Cervical Cancer	4	4
Chemotherapy and Radiation Toxicity	2	4
Colorectal Cancer	4	4
Gout	1	4
Helicobacter Pylori Infection	2	4
Hyperuricemia	1	4
Insomnia	1	4
Lead Poisoning	2	4
Neuroblastoma	3	4
Opiate Tolerance	1	4
Post-Traumatic Stress Disorders (PTSD)	2	4
Pseudomonas aeruginosa	3	4
Cadmium Poisoning	2	3
Influenza	3	3
Mitochondrial Dysfunction	2	3
Pain	2	3
Pancreatic Cancer	2	3
Periodontitis	2	3
Pesticide Toxicity	2	3
Stroke: Ischemic	2	3
Acquired Immunodeficiency Syndrome	2	2
Acrylamide-induced toxicity	1	2
Air Pollution Linked Toxicity	1	2
Alcoholic Liver Disease	1	2
Athletic Performance	1	2
Autoimmune Diseases	1	2
Brain Ischemia	1	2
Cancer Metastasis	1	2
Cardiac Hypertrophy	1	2
Cerebral Stroke	1	2
Chemotherapy	1	2
Chemotherapy-Induced Toxicity: Bleomycin	1	2
Chemotherapy-Induced Toxicity: Gentamicin	1	2
Cholesterol: LDL/HDL ratio	1	2
Colorectal Cancer: Prevention	1	2
Degenerative Disk Disease	1	2
Diabetes: Oxidative Stress	1	2
Diabetic Nephropathy	1	2
Diabetic Retinopathy	1	2
Diarrhea	1	2
Drug Toxicity: Methotrexate	1	2
Dysbiosis	1	2
Endometriosis	1	2
Erythema	1	2
Escherichia coli Infections	2	2
Esophageal Cancer	1	2
Fibrinogen: Elevated	1	2
Food Allergies	1	2
Gastric Ulcers	1	2
Gastritis	1	2
Gastrointestinal Inflammation	1	2
Glioma	2	2
Gram-Positive Bacterial Infections	1	2
Heart Disease	1	2
Heart Failure	1	2
Herpes Simplex Virus Type 1	2	2
Hyperalgesia	1	2
Infants: Low Birth Weight	1	2
Infertility: Male	1	2
Intestinal Ischemia	1	2
Intracerebral Hemorrhage	1	2
Kidney Damage: Drug-Induced	1	2
Kidney Fibrosis	1	2
Liver Damage: Drug-Induced	1	2
Low Testosterone	1	2
Lung Damage	1	2
Malaria	1	2
Malignant Melanoma	1	2
Mastitis	1	2
Mesothelioma	1	2
Middle Cerebral Artery Occlusion (MCAO)	1	2
Mycotoxin Toxicity	1	2
Myocardial Fibrosis	1	2
Myocarditis: Autoimmune	1	2
Osteoporosis: Age-Related	1	2
Osteosarcoma	1	2
Pancreatitis	1	2
Pancreatitis: Chronic	1	2
Pesticide Toxicity: Permethrin	1	2
Prehypertension	1	2
Promyelocytic leukemia	2	2
Pulmonary Fibrosis	1	2
Pulmonary Fibrosis: Bleomycin-Induced	1	2
Radiation Induced Illness	1	2
Seizures	1	2
Spinal Cord Injuries	1	2
Sunburn	1	2
Systemic Lupus Erythematosus	1	2
Testicular Diseases	1	2
Thrombosis	1	2
Triglycerides: Elevated	1	2
Tuberculosis	2	2
Tumors	1	2
Wound Healing	2	2
Acute Myeloid Leukemia	1	1
Amyloidosis	1	1
Amyotrophic Lateral Sclerosis	1	1
Benzo[a]pyrene-induced Toxicity	1	1
Bladder Cancer	1	1
Blue Light Toxicity	1	1
Brain: Microglial Activation	1	1
Breast Cancer: Bone Metastasis	1	1
Campylobacter Infections	1	1
Cancers: Drug Resistant	1	1
Candida Albicans	1	1
Candida Glabrata	1	1
Candida Infection	1	1
Carcinoma: Non-Small-Cell Lung	1	1
Chemotherapy-Induced Toxicity: Cyclophosphamide	1	1
Chronic Myeloid Leukemia	1	1
Chronic Obstructive Pulmonary Disease	1	1
Common Cold	1	1
Cystic Fibrosis	1	1
Dementia	1	1
Dementia: Alzheimer Type	1	1
Drug-Induced Toxicity: L-Thyroxine	1	1
Dry Eye Syndromes	1	1
Duchenne's Muscular Dystrophy	1	1
Ebola Virus Infections	1	1
Epilepsy	1	1
Eye Diseases	1	1
Foodborne Pathogens: Prevention/Food Preservation	1	1
Fungus Diseases	1	1
Gastrointestinal Diseases	1	1
Glioblastoma Multiforme	1	1
HDL: Low	1	1
Head and Neck Cancer	1	1
Hepatitis B	1	1
High Homocysteine	1	1
Infection: Antibiotic Resistant	1	1
Ischemia: Myocardial	1	1
Leukemia: Acute myelogenous leukemia (AML)	1	1
Lymphedema	1	1
Mercury Poisoning	1	1
Multiple Myeloma	1	1
Muscle Atrophy	1	1
Mycoplasma Infections	1	1
Neuromuscular Diseases	1	1
Oral Cancer	1	1
Pleurisy	1	1
Pregnancy Complications	1	1
Pulmonary Emphysema	1	1
Radiation	1	1
Respiratory Tract Infections	1	1
Rhabdovirus Infections	1	1
Rotavirus Infections	1	1
Squamous cell carcinoma	1	1
Staphylococcal Infections	1	1
Staphylococcus aureus: Methicillin-resistant (MRSA)	1	1
Steptococcus Mutans Infections	1	1
Testicular Cancer	1	1
Vibrio Infections	1	1

Name	AC	CK
Anti-Inflammatory Agents	139	374
Antioxidants	158	336
Neuroprotective Agents	61	118
Hypolipidemic	18	96
Tumor Necrosis Factor (TNF) Alpha Inhibitor	33	90
Cardioprotective	27	87
Hepatoprotective	33	86
Interleukin-6 Downregulation	23	71
Apoptotic	38	64
Antiproliferative	41	59
Interleukin-1 beta downregulation	20	51
NF-kappaB Inhibitor	22	50
Antihypertensive Agents	12	48
Hypoglycemic Agents	11	47
Anti-Apoptotic	27	45
Cyclooxygenase 2 Inhibitors	17	44
Gastrointestinal Agents	14	43
Renoprotective	19	40
Chemoprotective Agents	14	34
Chemotherapeutic	18	30
Antiviral Agents	17	29
Insulin Sensitizers	5	28
Malondialdehyde Down-regulation	9	26
Analgesics	6	20
Anti-atherogenic	6	20
Chemopreventive	12	20
Interleukin-10 upregulation	2	20
Interleukin-8 downregulation	6	20
Anti-metastatic	13	18
Anticholesteremic Agents	5	18
MicroRNA modulator	9	18
Anti-Bacterial Agents	13	17
Immunomodulatory	8	16
Superoxide Dismutase Up-regulation	9	16
Vascular Cell Adhesion Molecule-1 Inhibitor	4	16
Anti-Fibrotic	7	15
Chemosensitizer	5	15
Antineoplastic Agents	6	14
Cell cycle arrest	10	14
Matrix metalloproteinase-2 (MMP-2) inhibitor	4	14
Antifungal Agents	4	13
Autophagy Up-regulation	8	13
Gastroprotective	6	13
Antioxidant	2	12
Chondroprotective	3	12
Interleukin-17 downregulation	2	12
Antioxidant Effects	1	10
Calcium Channel Blockers	1	10
Genoprotective	4	10
Hypotensive	1	10
Nrf2 activation	7	10
Prophylactic Agents	1	10
Osteoprotective	4	7
Anti-Ulcer Agents	2	6
Antidepressive Agents	3	6
Antimycobacterial	2	6
Matrix metalloproteinase-1 (MMP-1) inhibitor	2	6
Neurogenesis	2	6
Vasodilator Agents	3	6
Anti-Retroviral Agents	1	5
Catalase Up-Regulation	3	5
Cytoprotective	4	5
Cytotoxic	4	5
Interferon-gamma (IFN-gamma) inducer	1	5
Leishmanicidal	2	5
Matrix metalloproteinase-3 (MMP-3) inhibitor	1	5
Radioprotective	3	5
Angiogenesis Inhibitors	3	4
Brain-derived neurotrophic factor modulator	2	4
Enzyme Inhibitors	1	4
Hypnotics and Sedatives	1	4
Matrix metalloproteinase-9 (MMP-9) inhibitor	3	4
Photoprotective	3	4
Xanthine oxidase inhibitor	1	4
Anti-Angiogenic	2	3
Anti-Glycation Agents	2	3
Antimicrobial	3	3
HIV Fusion Inhibitors	1	3
Heme oxygenase-1 up-regulation	2	3
Interferon Gamma Reducer	2	3
Nitric Oxide Inhibitor	1	3
SIRT1 Activator	2	3
Topoisomerase II Inhibitor	1	3
Transforming growth factor beta (TGF-β) inhibitor	1	3
Vascular Endothelial Growth Factor A Inhibitor	2	3
Acetylcholinesterase Inhibitor	1	2
Anti-Anxiety Agents	1	2
Anti-Platelet	1	2
Anticonvulsants	1	2
Antimalarials	1	2
Antimutagenic Agents	1	2
Autophagy Inhibitors	1	2
Bax/Bcl2 Ratio: Decrease	1	2
Cardiovascular Agents	1	2
Caspase-3 Inhibition	1	2
Fertility Agents: Female	1	2
Fibroblast growth factor 21 upregulation	1	2
Glucagon Like peptide 1 (GLP-1) Up-regulation	1	2
Glutathione Peroxidase 1 (GPx1) Up-Regulation	1	2
Glutathione Upregulation	1	2
HIV-1 Integrase Inhibitor	1	2
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	1	2
P21 Activation	2	2
Phase I Detoxification Enzyme Inducer	1	2
Phase II Detoxification Enzyme Inducer	1	2
Quorum Sensing Inhibition	2	2
Thermogenic	1	2
Tumor Suppressor Protein p53 Upregulation	2	2
Vascular Endothelial Growth Factor C Inhibitor	1	2
Vascular Endothelial Growth Factor D Inhibitor	1	2
Vascular Endothelial Growth Factor Inhibitors	1	2
Wnt/β-catenin pathway down-regulation	1	2
Wnt/β-catenin signaling pathway modulation	1	2
Anti-HIV Agents	1	1
Anti-Proliferative	1	1
Anticarcinogenic Agents	1	1
Antinoceceptive	1	1
Antitubercular Agents	1	1
Cyclin D1 Down-Regulation	1	1
Cyclooxygenase 1 Inhibitor	1	1
Epidermal growth factor receptor (EGFR) inhibitor	1	1
Histone deacetylase inhibitor	1	1
Immunostimulatory	1	1
Insulin-releasing	1	1
Intercellular adhesion molecule 3 down-regulation	1	1
Interleukin-18 down-regulation	1	1
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	1	1
Neurominidase Inhibitor	1	1
PI3K/Akt/signaling suppression	1	1
Pancreato Protective Agents	1	1
Postaglandin PGE2 downregulation	1	1
Proteasome Inhibitors	1	1
Radiosensitizer	1	1
Scolicidal	1	1
apoptosis	1	1

[+]

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Antioxidants (Basel). 2020 Sep 15 ;9(9). Epub 2020 Sep 15. PMID: 32942738

Article Published Date : Sep 14, 2020

Study Type : Human Study

Additional Links

Substances : Fruit: All, Olive leaf extract

Diseases : Hypertension

Pharmacological Actions : Antihypertensive Agents

Additional Keywords : Plant Extracts

[+]

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Pubmed Data : Nutrients. 2019 Dec 16 ;11(12). Epub 2019 Dec 16. PMID: 31888255

Article Published Date : Dec 15, 2019

Study Type : Human Study

Additional Links

Substances : Grape, Olive leaf extract, Polyphenols

Diseases : Osteoarthritis

Pharmacological Actions : Anti-Inflammatory Agents, Chondroprotective, Interleukin-1 beta downregulation, NF-kappaB Inhibitor

Additional Keywords : Plant Extracts, Proanthocyanidins

[+]

Combined supplementation of amla, walnut, and olive extracts, and RYR powder exerts a significant antihyperlipidemic effect.Dec 31, 2022

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Pubmed Data : Front Pharmacol. 2023 ;14:1280234. Epub 2023 Nov 27. PMID: 38089061

Article Published Date : Dec 31, 2022

Study Type : Human Study

Additional Links

Substances : Amla Fruit, Olive leaf extract, Red Yeast Rice, Walnut

Diseases : Hypercholesterolemia, Hyperlipidemia

Pharmacological Actions : Hypolipidemic

[+]

[+]

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Pubmed Data : Int J Epidemiol. 2002 Apr;31(2):474-80. PMID: 11980820

Article Published Date : Apr 01, 2002

Study Type : Human Study

Additional Links

Substances : Olive

Diseases : Coronary Artery Disease, Myocardial Infarction

Additional Keywords : Risk Reduction

[+]

Olive oil consumption is associated with reduced incidence of ovarian cancer. Jun 01, 2002

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Pubmed Data : Cancer Causes Control. 2002 Jun;13(5):465-70. PMID: 12146851

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Pubmed Data : Alzheimers Dement (N Y). 2022 ;8(1):e12278. Epub 2022 Mar 13. PMID: 35310529

Article Published Date : Dec 31, 2021

Study Type : Human Study

Additional Links

Substances : Glutathione, Olive

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Omega-3 dietary supplementation may have a therapeutic effect in blepharitis and meibomian gland dysfunction.Jan 01, 2008

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Pubmed Data : Trans Am Ophthalmol Soc. 2008;106:336-56. PMID: 19277245

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Flaxseed, Olive, Omega-3 Fatty Acids

Diseases : Blepharitis, Meibomian gland dysfunction

[+]

Oral supplement containing hydroxytyrosol and punicalagin improves dyslipidemia.Apr 28, 2022

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Pubmed Data : J Natl Cancer Inst. 1995 Jan 18;87(2):110-6. PMID: 7503842

Article Published Date : Jan 18, 1995

Study Type : Human Study

Additional Links

Substances : Fruit: All, Olive, Olive Oil, Vegetables: All

Diseases : Breast Cancer: Prevention

Additional Keywords : Inverse Relationship, Risk Reduction

[+]

The effect of dietary intervention with high-oleocanthal and oleacein olive oil in Patients with early-stage chronic lymphocytic leukemia.Dec 31, 2020

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Pubmed Data : Pak J Biol Sci. 2019 Jan ;22(7):342-348. PMID: 31930845

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Pubmed Data : Nutrients. 2017 Apr 15 ;9(4). Epub 2017 Apr 15. PMID: 28420140

Article Published Date : Apr 14, 2017

Study Type : Human Study

Additional Links

Substances : Oleuropein

Diseases : Ulcerative Colitis

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-17 downregulation

[+]

Topical rosemary essential oil increased warmth perception in patients with systemic sclerosis-related Raynaud's phenomenon.Dec 31, 2021

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Pubmed Data : Complement Med Res. 2022 ;29(3):242-248. Epub 2022 Feb 9. PMID: 35139518

Article Published Date : Dec 31, 2021

Study Type : Human Study

Additional Links

Substances : Olive, Rosemary

Diseases : Raynaud Disease

[+]

Usefulness of extra virgin olive oil minor polar compounds in the management of chronic kidney disease patients.Feb 09, 2021

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Pubmed Data : Food Funct. 2016 Nov 21. Epub 2016 Aug 21. PMID: 27869910

Consumption of citrus fruit and olive leaf extract have beneficial effects on lipid metabolism.Sep 25, 2017

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Pubmed Data : Antioxidants (Basel). 2023 Jun 19 ;12(6). Epub 2023 Jun 19. PMID: 37372034

Article Published Date : Jun 18, 2023

Study Type : Animal Study

Additional Links

Substances : Olive, Polyphenols

Diseases : Endothelial Dysfunction, Systemic Lupus Erythematosus

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Epigenetic Modification

[+]

Effects of emulsion formulations of oleuropein isolated from ethanol extract of olive leaf in diabetic rats.Dec 31, 2019

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Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:8487248. Epub 2018 Apr 26. PMID: 30013722

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Olive leaf extract

Diseases : Chemotherapy-Induced Toxicity: Cisplatin

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents, Heme oxygenase-1 up-regulation, Nrf2 activation

[+]

EVOO polyphenols relieve synergistically autophagy dysregulation in a cellular model of Alzheimer's disease.Jul 04, 2021

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Pubmed Data : Int J Mol Sci. 2021 Jul 5 ;22(13). Epub 2021 Jul 5. PMID: 34281279

Article Published Date : Jul 04, 2021

Study Type : Animal Study

Additional Links

Substances : Oleuropein, Olive Oil, Polyphenols

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

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Pubmed Data : Nutrition. 2021 Dec 26 ;97:111579. Epub 2021 Dec 26. PMID: 35248848

Article Published Date : Dec 25, 2021

Study Type : Animal Study

Additional Links

Substances : Hydroxytyrosol

Diseases : Colitis

Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents

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Hydroxytyrosol alleviates methotrexate-induced pulmonary fibrosis in rats.Dec 31, 2023

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Hydroxytyrosol attenuates ethanol-induced liver injury.Nov 30, 2023

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Memory recovery effect of a new bioactive innovative combination in rats with experimental dementia.Nov 27, 2023

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Pubmed Data : Antioxidants (Basel). 2023 Nov 28 ;12(12). Epub 2023 Nov 28. PMID: 38136170

Article Published Date : Nov 27, 2023

Study Type : Animal Study

Additional Links

Substances : Alpha-Lipoic Acid, Citicoline, Green Tea, Olive leaf extract, Selenium, Vitamin D

Diseases : Dementia

Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Neuroprotective Agents, Superoxide Dismutase Up-regulation

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Nephroprotective effect of the virgin olive oil polyphenol hydroxytyrosol in type 1-like experimental diabetes mellitus.Nov 07, 2021

Article Published Date : Apr 30, 2024

Study Type : Animal Study

Additional Links

Substances : Oleuropein

Diseases : Chemotherapy, Kidney Damage: Drug-Induced

Pharmacological Actions : Chemoprotective Agents, Renoprotective

[+]

Oleuropein might be a potential useful therapeutic intervention for PTSD.Sep 06, 2017

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Pubmed Data : J Nat Med. 2017 Sep 7. Epub 2017 Sep 7. PMID: 28884427

Article Published Date : Sep 06, 2017

Study Type : Animal Study

Additional Links

Substances : Oleuropein

Diseases : Brain Inflammation , Post-Traumatic Stress Disorders (PTSD)

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

[+]

Oleuropein mitigates acrylamide-induced nephrotoxicity. Sep 30, 2023

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Pubmed Data : Eurasian J Med. 2023 Oct ;55(3):228-233. PMID: 37909193

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Pubmed Data : Anim Cells Syst (Seoul). 2018 ;22(2):109-117. Epub 2018 Mar 13. PMID: 30460087

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Oleuropein

Diseases : Post-Traumatic Stress Disorders (PTSD)

Pharmacological Actions : Anti-Anxiety Agents

[+]

Oleuropein reverses repeated corticosterone-induced depressive-like behaviour.Jan 23, 2020

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Pubmed Data : Mol Nutr Food Res. 2015 Sep 29. Epub 2015 Sep 29. PMID: 26502315

Article Published Date : Sep 28, 2015

Study Type : Animal Study

Additional Links

Substances : Oleuropein

Diseases : Colitis, Colorectal Cancer: Prevention

Pharmacological Actions : Anti-Inflammatory Agents, Chemopreventive, Interferon Gamma Reducer, Interleukin-17 downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Wnt/β-catenin pathway down-regulation

[+]

Oleuropein suppresses endometriosis progression and improves the fertility of mice with endometriosis.Nov 21, 2022

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Pubmed Data : Eur Rev Med Pharmacol Sci. 2024 Feb ;28(4):1259-1271. PMID: 38436159

Article Published Date : Jan 31, 2024

Study Type : Animal Study

Additional Links

Substances : Oleuropein

Diseases : Chemically-Induced Liver Damage, Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective

[+]

Oleuropein, a phenolic compound in extra virgin olive oil enhances thermogenesis and noradrenaline and andrenaline secretion in rats. Oct 01, 2008

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Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2008 Oct;54(5):363-70. PMID: 19001767

Article Published Date : Oct 01, 2008

Study Type : Animal Study

Additional Links

Substances : Olive

Pharmacological Actions : Thermogenic

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Oleuropein-rich leaf extract as a broad inhibitor of tumour and macrophage iNOS in an Apc mutant rat model.Oct 05, 2021

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Pubmed Data : Antioxidants (Basel). 2021 Oct 6 ;10(10). Epub 2021 Oct 6. PMID: 34679712

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Pubmed Data : Iran J Kidney Dis. 2012 Jan ;6(1):25-32. PMID: 22218116

Article Published Date : Jan 01, 2012

Study Type : Animal Study

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Substances : Olive leaf extract

Diseases : Chemotherapy-Induced Toxicity: Gentamicin

Pharmacological Actions : Antioxidants, Glutathione Upregulation , Renoprotective

Problem Substances : Gentamicin

Adverse Pharmacological Actions : Nephrotoxic, Oxidant

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Olive leaf extract and glutamine significantly increase GLP-1 up-regulation. Sep 01, 2011

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Pubmed Data : Sci Pharm. 2011 Sep ;79(3):615-621. Epub 2011 Jun 9. PMID: 21886907

Article Published Date : Sep 01, 2011

Study Type : Animal Study

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Substances : Glutamine, Olive leaf extract

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Glucagon Like peptide 1 (GLP-1) Up-regulation

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Olive leaf extract attenuates chlorpyrifos-induced neuro-and reproductive toxicity.Sep 26, 2022

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Pubmed Data : Life (Basel). 2022 Sep 27 ;12(10). Epub 2022 Sep 27. PMID: 36294935

Article Published Date : Sep 26, 2022

Study Type : Animal Study

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Substances : Olive leaf extract

Diseases : Pesticide Toxicity

Pharmacological Actions : Antioxidants, Neuroprotective Agents

Problem Substances : Chlorpyrifos

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Olive leaf extract can inhibit lead-induced brain injury by increasing antioxidant capacity and reducing apoptosis.Aug 04, 2013

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Pubmed Data : Neural Regen Res. 2013 Aug 5 ;8(22):2021-9. PMID: 25206510

Article Published Date : Aug 04, 2013

Study Type : Animal Study

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Substances : Olive leaf extract

Diseases : Brain: Oxidative Stress, Lead Poisoning, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Catalase Up-Regulation, Neuroprotective Agents, Superoxide Dismutase Up-regulation

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Olive leaf extract is a promising chemotherapeutic agent for reducing the toxicity of carbendazim and possibly other pesticides and toxicants.Apr 01, 2011

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Pubmed Data : Eur Rev Med Pharmacol Sci. 2011 Apr ;15(4):413-26. PMID: 21608437

Article Published Date : Apr 01, 2011

Study Type : Animal Study

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Substances : Olive leaf extract

Therapeutic Actions : anti-cancer, anti-carcinogenic role

Pharmacological Actions : Chemotherapeutic

Additional Keywords : Anti-cancer, Olive Leaf Extract, Phytotherapy, Plant Extracts

Problem Substances : Pesticides

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Olive leaf extract prevents spontaneous occurrence of non-alcoholic fatty liver in rats.Jan 01, 2010

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Pubmed Data : Pathology. 2010 Jan;42(1):66-72. PMID: 20025483

Article Published Date : Jan 01, 2010

Study Type : Animal Study

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Substances : Oleuropein, Olive leaf extract

Diseases : Fatty Liver

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Olive leaf extract protect against L-arginine induced chronic pancreatitis.Jun 29, 2022

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Pubmed Data : Anat Cell Biol. 2022 Jun 30 ;55(2):205-216. PMID: 35773220

Article Published Date : Jun 29, 2022

Study Type : Animal Study

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Substances : Olive leaf extract

Diseases : Pancreatitis: Chronic

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants

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Olive leaf extract protects against the genetic and oxidative damage by permethrin in vivo.Jan 20, 2012

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Pubmed Data : Cytotechnology. 2012 Jan 20. Epub 2012 Jan 20. PMID: 22262123

Article Published Date : Jan 20, 2012

Study Type : Animal Study

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Substances : Olive leaf extract

Diseases : DNA damage, Oxidative Stress, Pesticide Toxicity: Permethrin

Pharmacological Actions : Antioxidants, Genoprotective

Problem Substances : Permethrin

Adverse Pharmacological Actions : Genotoxic, Oxidant

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Olive leaf extract reduces oxidative stress and oxidative stress-related glucose metabolism disruption induced by 2.45 GHz Wi-Fi signals.Nov 01, 2013

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Pubmed Data : Environ Toxicol Pharmacol. 2013 Nov ;36(3):826-34. Epub 2013 Aug 3. PMID: 23994945

Article Published Date : Nov 01, 2013

Study Type : Animal Study

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Pubmed Data : Int J Fertil Steril. 2019 Apr ;13(1):57-65. Epub 2019 Jan 6. PMID: 30644246

Article Published Date : Mar 31, 2019

Study Type : Animal Study

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Substances : Olive leaf extract

Diseases : Chemotherapy and Radiation Toxicity

Pharmacological Actions : Chemoprotective Agents

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Patchouli alcohol against renal fibrosis of spontaneously hypertensive rats.Jul 04, 2023

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Pubmed Data : J Pharm Pharmacol. 2023 Jul 5 ;75(7):995-1010. PMID: 37177974

Article Published Date : Jul 04, 2023

Study Type : Animal Study

Additional Links

Substances : Olive

Diseases : Hypertension, Kidney Fibrosis

Pharmacological Actions : Anti-Fibrotic, Renoprotective

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View the Evidence: 558 Abstracts with Olive Research

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Olive leaf extract effect on cardiometabolic risk factors.Jan 28, 2024

The effects of olive leaf extract on cardiovascular risk factors in the general adult population.Oct 20, 2022

Efficacy and safety of dietary polyphenols in rheumatoid arthritis.Dec 31, 2022

A combination of olive leaf and fruit extracts may be used efficiently and safely in reducing hypertension and MetS markers.Sep 14, 2020

A combination of garlic, mullein, calendula, st. johns wort and olive oil is as effective as an anesthetic drug for the management of acute otitis media-associated pain. Jul 01, 2001

A combination of hydroxytyrosol, omega-3 fatty acids and curcumin improves pain and inflammation among early stage breast cancer patients.Mar 31, 2019

A combination of red yeast rice and olive extract in high-risk hypercholesterolemic patients, without inducing new-onset SAMS.Nov 30, 2017

A Mediterranean diet (that emphasizes olive oil, fiber, fruits, vegetables, fish and alcohol and reduces meat/meat products) can be an effective measure for reducing the risk of myocardial infarction.Apr 01, 2005

A Mediterranean diet rich in olive oil may have a protective role in multiple sclerosis. Jun 01, 2009

A Mediterranean diet rich in virgin olive oil is associated with high plasma antioxidant capacity and reduced body weight gain.Dec 01, 2009

A mixture of honey, olive oil and beeswax is safe and effective for hemorrhoids and anal fissure.Feb 02, 2006

A mixture of natural honey, beeswax and olive oil appears useful in the management of dermatitis and psoriasis vulgaris.Dec 01, 2003

A nut-enriched diet has cholesterol-lowering properties, and olive oil has a cholesterol-lowering property independent of its fatty acid content. May 31, 2011

A red yeast rice-olive extract supplement reduces biomarkers of oxidative stress, OxLDL and Lp-PLA2, in subjects with metabolic syndrome.Jul 02, 2017

A standardized extract of Opuntia ficus-indica (L.) Mill and Olea europaea L. improves gastrointestinal discomfort.Mar 15, 2021

Adherence to a diet comprising mostly fruits, vegetables, fish, and olive/sunflower oil, along with avoidance of Western-type foods, may contribute to a substantial reduction in postmenopausal breast cancer risk.Nov 15, 2009

Adherence to a Mediterranean dietary pattern may protect against coronary artery wall production of inflammatory mediators in patients with unstable angina pectoris. Sep 01, 2005

Administration of olive oil followed by a low volume of polyethylene glycol-electrolyte lavage solution improves patient satisfaction with right-side colonic cleansing over conventional preparation. Sep 01, 2009

An onion-olive-oil combination reduces arterial blood pressure, plasma viscosity and hematocrit, indicating the cardiovascular benefits of a Mediterranean diet. Sep 01, 2000

Antioxidant activity of hydroxytyrosol and vitamin E reduces systemic inflammation in children with paediatric NAFLD.Oct 11, 2020

Association of hydroxytyrosol enriched olive oil with vascular function in chronic coronary disease.Jun 30, 2023

Chondroprotective properties of human-enriched serum following polyphenol extract absorption.Dec 15, 2019

Combined supplementation of amla, walnut, and olive extracts, and RYR powder exerts a significant antihyperlipidemic effect.Dec 31, 2022

Extra virgin olive oil mitigates postprandial lipopolysaccharide-induced inflammation and oxidative stress.Mar 01, 2019

Food fried in extra-virgin olive oil improves postprandial insulin response in obese, insulin-resistant women.Dec 13, 2010

Hibiscus sabdariffa and Olea europaea had comparable antihypertensive efficacy and safety to captopril in Egyptian patients with grade 1 hypertension.Jul 28, 2020

Hydroxytyrosol changed body composition parameters and modulated the antioxidant profile, the expression of inflammation and oxidative stress-related genes.Dec 31, 2016

Hydroxytyrosol is effective and safe in preventing recurrent candida episodes.Jun 30, 2020

Hydroxytyrosol, a promising supplement in the management of human stroke.Apr 26, 2024

Leaf extract from european olive post-transcriptionally suppresses the epithelial-mesenchymal transition and sensitizes gastric cancer cells to chemotherapy.Dec 31, 2023

Mediterranean diet enriched in extra-virgin olive oil or nuts modulates circulating exosomal non-coding RNAs.Nov 30, 2021

Mediterranean diets supplemented with olive oil or nuts have beneficial effects on cardiovascular risk factors.Jul 04, 2006

Mucosave formulation is an effective treatment for reducing the frequency and intensity of symptoms associated with gastroesophageal reflux.Dec 31, 2015

Naturopathic treatment for ear pain is demonstrated superior to antibiotic treatment.May 01, 2003

OLE prevents the loss of muscle mass associated with aging and exerts anti-inflammatory and insulin-sensitizing effects on adipose tissue and skeletal muscle.May 06, 2021

Olive (Olea europaea L.) leaf polyphenols improve insulin sensitivity in middle-aged overweight men.Dec 31, 2012

Olive (Olea europaea) leaf extract, at the dosage regimen of 500 mg twice daily, was similarly effective in lowering systolic and diastolic blood pressures in subjects with stage-1 hypertension as Captopril, given at its effective dose of 12.5-25 mg twiceFeb 14, 2011

Olive fruit and almond skin extract seems to protect LDL from oxidation and to prevent inflammatory status in moderately hypercholesterolemic subjects.Aug 17, 2020

Olive leaf extract can improve the clinical status of the patients and decrease the length of hospitalization.Oct 28, 2022

Olive leaf extract has a beneficial effects on upper respiratory illness in high school athletes. Feb 08, 2019

Olive leaf extract has calcium channel blocking activity consistent with its traditional role in the treatment of cardiovascular disease. Nov 20, 2008

Olive leaf tea is beneficial for lipid metabolism in adults with prediabetes.May 10, 2019

Olive oil consumption appears to reduce the risk of non-fatal heart attack in coronary disease. Apr 01, 2002

Olive oil consumption is associated with reduced incidence of ovarian cancer. Jun 01, 2002

Olive oil consumption reduces the susceptibility of LDL to oxidation, supporting the hypothesis that daily virgin olive oil intake protects cardiovascular health. Dec 01, 2007

Olive oil during pregnancy is associated with reduced wheezing during the first year of life of the offspring.Apr 01, 2010

Olive oil inhibits ageing signs induced by chronic stress.Mar 31, 2019

Olive polyphenols and bioavailable glutathione: Promising results in patients diagnosed with mild Alzheimer's disease.Dec 31, 2021

Omega-3 dietary supplementation may have a therapeutic effect in blepharitis and meibomian gland dysfunction.Jan 01, 2008

Oral supplement containing hydroxytyrosol and punicalagin improves dyslipidemia.Apr 28, 2022

Our results support the protective role of olive oil consumption on breast cancer among Canaries women.Feb 01, 2006

Supplementation with hydroxytyrosol and punicalagin improves early atherosclerosis markers.Mar 15, 2019

Supplementation with omega-3 fatty acids in pregnancy is associated with increased omega-3 fatty acids in breast milk and is positively associated with infant DHA status at 1 y.Dec 01, 2007

The combination of D-mannose, inulin, cranberry, bearberry, Olea europaea, Orthosiphon and Lactobacillus acidophilus SGL 11 per os represents a useful therapy for recurrent UTIs.Aug 31, 2020

The consumption of vegetables and fruits are inversely, significantly and strongly associated with breast cancer risk. There also is evidence that olive oil consumption may reduce the risk of breast cancer. Jan 18, 1995

The effect of dietary intervention with high-oleocanthal and oleacein olive oil in Patients with early-stage chronic lymphocytic leukemia.Dec 31, 2020

The efficacy of honey or olive oil on the severity of oral mucositis and pain compared.Dec 31, 2022

The potential preventive role of a dietary supplement containing hydroxytyrosol in COVID-19.Nov 30, 2023

The results concluded that inflammation as a major cause of hypertension was significantly decreased in patients using olive leaf extract tablets.Dec 31, 2018

The topical application of a honey, olive oil and beeswax mixture has therapeutic effects in patients with Pityriasis Versicolor and Tinea. Mar 01, 2004

The topical application of honey, olive oil and beeswax has benefits in diaper dermatitis.Feb 01, 2005

These findings indicate that oleuropein improves postprandial glycaemic profile via hampering Nox2-derived oxidative stress.Mar 25, 2018

These new data support a potential role of oleuropein in the treatment of ulcerative colitis.Apr 14, 2017

Topical rosemary essential oil increased warmth perception in patients with systemic sclerosis-related Raynaud's phenomenon.Dec 31, 2021

Usefulness of extra virgin olive oil minor polar compounds in the management of chronic kidney disease patients.Feb 09, 2021

Vitamin E and hydroxytyrosol may be a promising strategy that could be easily diet integrated to improve NAFLD-related liver damage in children.Feb 10, 2019

5-Hydroxytyrosol inhibits HIV-1 replication in primary cells of the lower and upper female reproductive tract.Dec 31, 2016

Ethanol extract of olive leaf extract induced its genoprotective effect via the increase in the antioxidant capacity, inhibition of oxidative stress and scavenging of free radicals.Oct 01, 2011

Hydroxytyrosol as a promising ally in the treatment of fibromyalgia.Aug 08, 2020

OLE may promote the brown remodelling of white adipose tissue inducing thermogenesis and improving metabolic homeostasis.Dec 31, 2015

Oleuropein is effective in antimycoplasmal activity.Oct 01, 2002

Oleuropein might provide a basis for developing a new dietary strategy for the prevention and management of rheumatoid arthritis.Apr 19, 2017

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View the Evidence:
558 Abstracts with Olive Research