Oregano

Name	AC	CK
Head Lice	1	10
Upper Respiratory Infections	1	10
Candida Infection	5	9
Oxidative Stress	3	6
Foodborne Pathogens: Prevention/Food Preservation	4	4
Liver Cancer	3	4
Liver Disease	1	4
Candidiasis	2	3
Escherichia coli Infections	2	3
ALT: Elevated	1	2
Aging	1	2
Alcohol Toxicity	1	2
Benzo[a]pyrene-induced Toxicity	1	2
Breast Cancer	1	2
Campylobacter Infections	1	2
Carcinoma: Non-Small-Cell Lung	1	2
Chemically-Induced Liver Damage	1	2
Chemotherapy and Radiation Toxicity	1	2
Chemotherapy-Induced Toxicity: Cyclophosphamide	1	2
Clostridium Infections	1	2
Cognitive Decline/Dysfunction	1	2
Dental Caries	1	2
Diabetic Complications	1	2
Drug-Induced Toxicity: Methotrexate	1	2
Enteropathy	1	2
Gamma-glutamyl transpeptidase: Elevated	1	2
Gram-Negative Bacterial Infections	2	2
Hypertension	1	2
Infection: Antibiotic Resistant	1	2
Inflammation	1	2
Mycobacterium Avium	1	2
Mycobacterium Infections	1	2
Parasitic Intestinal Diseases	1	2
Salmonella Infections	2	2
Staphylococcus aureus infection	2	2
Steptococcus Mutans Infections	1	2
Xenobiotic Exposures	1	2
Acetaminophen (Tylenol) Toxicity	1	1
Acute Myeloid Leukemia	1	1
Bacterial Infections and Mycoses	1	1
Cholesterol: Oxidation	1	1
Colon Cancer	1	1
Cystic Fibrosis: Infections	1	1
Dermatophytoses	1	1
Fungal Infection	1	1
Gastric Cancer	1	1
Giardiasis	1	1
Herpes Simplex Virus Type 1	1	1
Listeria Infections	1	1
Lyme Disease	1	1
Metabolic Syndrome X	1	1
Protozoan Infections	1	1
Staphylococcal Infections	1	1
Trichophytosis	1	1
Vibrio Infections	1	1

Name	AC	CK
Antifungal Agents	8	13
Anti-Bacterial Agents	9	11
Antiproliferative	6	9
Antioxidants	5	8
Antimicrobial	6	7
Apoptotic	5	7
Anti-Apoptotic	3	6
Hepatoprotective	2	3
Alpha-amylase inhibitor	1	2
Angiogenesis Inhibitors	1	2
Anti-Inflammatory Agents	1	2
Antihypertensive Agents	1	2
Antiparasitic Agents	1	2
Bcl-xL down-regulation	1	2
Chemoprotective Agents	1	2
Cyclooxygenase 2 Inhibitors	1	2
Gastroprotective	1	2
Hypoglycemic Agents	1	2
Hypolipidemic	1	2
NF-kappaB Inhibitor	1	2
Neuroprotective Agents	1	2
Phase I Detoxification Enzyme Inducer	1	2
Phase II Detoxification Enzyme Inducer	1	2
Radioprotective	1	2
Renoprotective	1	2
Antiprotozoal Agents	1	1
Antiviral Agents	1	1
Cell cycle arrest	1	1
Chemotherapeutic	1	1
Cytotoxic	1	1

[+]

A spray containing eucalyptus, peppermint, oregano and rosemary improves symptoms of upper respiratory infection.Jan 01, 2011

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Pubmed Data : Evid Based Complement Alternat Med. 2011;2011:690346. Epub 2010 Nov 1. PMID: 21052500

Article Published Date : Jan 01, 2011

Study Type : Human Study

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Substances : Eucalyptus, Oregano, Peppermint, Rosemary

Diseases : Upper Respiratory Infections

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Carvacrol ameliorates haematological parameters, antioxidant biomarkers and pulmonary function in patients with sulphur mustard-induced lung disorders.Mar 24, 2018

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Pubmed Data : J Clin Pharm Ther. 2018 Mar 25. Epub 2018 Mar 25. PMID: 29574804

Article Published Date : Mar 24, 2018

Study Type : Human Study

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Substances : Carvacrol

Diseases : Chemical Weapon Agent Injury: Sulfur Mustard

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Problem Substances : Mustard Gas

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Carvacrol reduced inflammatory cytokine and chemokine while increased anti-inflammatory cytokines in veterans exposed to mustard gas.Mar 31, 2019

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Pubmed Data : Respir Med. 2019 Apr ;150:21-29. Epub 2019 Feb 5. PMID: 30961947

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Pubmed Data : Planta Med. 2007 Oct;73(13):1365-71. Epub 2007 Oct 9. PMID: 17924312

Article Published Date : Oct 01, 2007

Study Type : Animal Study

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Substances : Carvacrol

Diseases : Hypertension

Pharmacological Actions : Antihypertensive Agents

[+]

Carvacrol has significant potential as an inhibitor of memory degeneration in neurodegenerative diseases.Dec 31, 2019

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Co-administration of curcumin or carvacrol and doxorubicin for 24 days could improve the heart function and structural changes.Oct 31, 2019

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Origanum vulgare essential oil is an effective counteractive treatment against cypermethrin-induced damage in exposed common carp.Sep 05, 2020

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Pubmed Data : Aquat Toxicol. 2020 Sep 6 ;228:105624. Epub 2020 Sep 6. PMID: 32947072

Article Published Date : Sep 05, 2020

Study Type : Animal Study

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Substances : Oregano

Diseases : Pesticide Toxicity: Cypermethrin

Pharmacological Actions : Antioxidants

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Origanum vulgare leaf extract protects mice bone marrow cells against ionizing radiation.Oct 31, 2016

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Pubmed Data : Avicenna J Phytomed. 2016 Nov-Dec;6(6):678-685. PMID: 28078248

Article Published Date : Oct 31, 2016

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Pubmed Data : Phytother Res. 2015 May ;29(5):730-6. Epub 2015 Feb 13. PMID: 25682768

Article Published Date : Apr 30, 2015

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Pubmed Data : Avicenna J Phytomed. 2019 Nov-Dec;9(6):563-573. PMID: 31763215

Article Published Date : Oct 31, 2019

Study Type : Animal Study

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Substances : Oregano

Diseases : Kidney Damage: Chemically-Induced, Paraquat Toxicity, Pesticide Toxicity

Pharmacological Actions : Antioxidants, Renoprotective

Problem Substances : Paraquat

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This study demonstrates a distinct tumour-suppressive effect of oregano in a breast cancer model.Feb 22, 2016

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Pubmed Data : Int J Antimicrob Agents. 2008 Jun;31(6):572-6. Epub 2008 Apr 28. PMID: 18440786

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Pubmed Data : Mycoses. 2013 May ;56(3):333-7. Epub 2013 Feb 1. PMID: 23368893

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Pubmed Data : Cytotechnology. 2003 Nov;43(1-3):149-54. PMID: 19003220

Article Published Date : Nov 01, 2003

Study Type : In Vitro Study

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Substances : Carvacrol, Oregano, Savory, Thyme

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Antiproliferative

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Carvacrol and thymol inhibit biofilm formation of carbapenemase-producing gram negative bacilli strains.May 19, 2017

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Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2017 May 20 ;63(5):108-112. Epub 2017 May 20. PMID: 28719354

Article Published Date : May 19, 2017

Study Type : In Vitro Study

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Substances : Carvacrol, Thymol

Diseases : Gram-Negative Bacterial Infections

Pharmacological Actions : Antimicrobial

Additional Keywords : Biofilm

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Carvacrol and thymol isolated from O. vulgare L. exhibit good bactericidal and antibiofilm activity against S. mutans.Nov 30, 2017

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Pubmed Data : AMB Express. 2017 Dec ;7(1):49. Epub 2017 Feb 23. PMID: 28233286

Article Published Date : Nov 30, 2017

Study Type : In Vitro Study

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Substances : Carvacrol, Oregano, Thymol

Diseases : Dental Caries, Steptococcus Mutans Infections

Pharmacological Actions : Antimicrobial

Additional Keywords : Biofilm

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Carvacrol could be a novel and strong anticancer agent against the human gastric adenocarcinoma.Feb 26, 2017

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Pubmed Data : Anticancer Drugs. 2017 Feb 27. Epub 2017 Feb 27. PMID: 28244942

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Pubmed Data : J Cell Physiol. 2019 Feb ;234(2):1803-1815. Epub 2018 Aug 2. PMID: 30070691

Article Published Date : Jan 31, 2019

Study Type : In Vitro Study

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Substances : Carvacrol

Diseases : Choriocarcinoma

Pharmacological Actions : Apoptotic

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Carvacrol inhibits cadmium toxicity through combating against caspase dependent/independent apoptosis in PC12 cells.Sep 24, 2019

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Pubmed Data : Food Chem Toxicol. 2019 Sep 25:110835. Epub 2019 Sep 25. PMID: 31562949

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Pubmed Data : J Periodontol. 2017 07 ;88(7):e120-e128. Epub 2017 Apr 7. PMID: 28387609

Article Published Date : Dec 31, 2016

Study Type : In Vitro Study

Additional Links

Substances : Carvacrol

Diseases : Periodontitis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Matrix metalloproteinase-9 (MMP-9) inhibitor

[+]

Carvacrol shows good anti-M. tuberculosis activity and synergism with rifampicin.Dec 31, 2017

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Pubmed Data : Future Microbiol. 2018 06 1 ;13:877-888. Epub 2018 Jun 7. PMID: 29877104

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Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:2421695. Epub 2019 Jan 15. PMID: 30766611

Article Published Date : Dec 31, 2018

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Pubmed Data : J Med Food. 2014 Oct ;17(10):1129-33. Epub 2014 Sep 17. PMID: 25230257

Article Published Date : Sep 30, 2014

Study Type : In Vitro Study

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Substances : Oregano

Diseases : Breast Cancer, Colon Cancer

Pharmacological Actions : Antiproliferative

Additional Keywords : Essential Oils, Plant Extracts

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Computational evaluation of major components from plant essential oils as potent inhibitors of SARS-CoV-2 spike protein.Dec 04, 2020

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Pubmed Data : J Mol Struct. 2020 Dec 5 ;1221:128823. Epub 2020 Jul 4. PMID: 32834111

Oregano kills Giardia intestinalis trophozoites in vitro.May 01, 2006

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Pubmed Data : Parasitol Res. 2006 May;98(6):557-60. Epub 2006 Jan 20. PMID: 16425064

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Pubmed Data : Heliyon. 2019 Oct ;5(10):e02625. Epub 2019 Oct 11. PMID: 31667426

Article Published Date : Sep 30, 2019

Study Type : In Vitro Study

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Substances : Oregano

Diseases : Klebsiella Infections, Proteus Vulgaris Infections, Staphylococcal Infections

Pharmacological Actions : Gastrointestinal Agents, Prophylactic Agents

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Origanum majorana showed apparent protective and curative effect on cadmium-induced hepatotoxicity and nephrotoxicity.Jul 31, 2011

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Pubmed Data : Saudi Med J. 2011 Aug ;32(8):797-805. PMID: 21858388

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Pubmed Data : Food Chem. 2014 ;152:300-6. Epub 2013 Dec 1. PMID: 24444941

Article Published Date : Dec 31, 2013

Study Type : In Vitro Study

Additional Links

Substances : Oregano

Diseases : Coxsackievirus Infections, Herpes Simplex Virus Type 1, Respiratory Syncytial Virus Infections

Pharmacological Actions : Antioxidants, Antiviral Agents

Additional Keywords : Plant Extracts

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Selective essential oils from spice or culinary herbs have high activity against stationary phase and biofilm Borrelia burgdorferi.Dec 31, 2016

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Pubmed Data : Front Med (Lausanne). 2017 ;4:169. Epub 2017 Oct 11. PMID: 29075628

Article Published Date : Dec 31, 2016

Study Type : In Vitro Study

Additional Links

Substances : Cinnamon, Clove, Oregano

Diseases : Lyme Disease

Pharmacological Actions : Antimicrobial

Additional Keywords : Biofilm, Essential Oils

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Studies with fresh meat, meat products, fish, milk, dairy products and cooked rice have shown that the concentration of essential oils needed to achieve a significant antibacterial effect is around 0.5 microl g (-1) in foods and about .1 - 10 microl ml (-Aug 01, 2004

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Pubmed Data : Int J Food Microbiol. 2004 Aug 1 ;94(3):223-53. PMID: 15246235

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Pubmed Data : PLoS One. 2014 ;9(4):e93414. Epub 2014 Apr 1. PMID: 24691035

Article Published Date : Dec 31, 2013

Study Type : In Vitro Study

Additional Links

Substances : Carvacrol

Diseases : Salmonella Infections, Staphylococcus aureus infection

Pharmacological Actions : Anti-Bacterial Agents, Quorum Sensing Inhibition

Additional Keywords : Biofilm

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This paper reviews classical methods for evaluating antibacterial and antifungal activity of essential oils and gives an overview on the susceptibility of human and food-borne bacteria and fungi towards different essential oils and their constituents.May 01, 2003

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Pubmed Data : Curr Med Chem. 2003 May ;10(10):813-29. PMID: 12678685

Article Published Date : May 01, 2003

Study Type : Review

Additional Links

Substances : Cinnamon, Mint, Oregano, Sage, Thyme

Diseases : Foodborne Pathogens: Prevention/Food Preservation

Pharmacological Actions : Anti-Bacterial Agents, Antifungal Agents

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This preliminary evaluation demonstrated a synergistic property of O. vulgare and H. perforatum extracts in treating S. aureus infection.Feb 28, 2019

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Pubmed Data : Future Sci OA. 2019 Mar ;5(3):FSO371. Epub 2019 Jan 31. PMID: 30906567

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Pubmed Data : Hum Exp Toxicol. 2016 Jan 22. Epub 2016 Jan 22. PMID: 26801986

Article Published Date : Jan 21, 2016

Study Type : In Vitro Study

Additional Links

Substances : Carvacrol, Thymol

Diseases : Acetaminophen (Tylenol) Toxicity

Pharmacological Actions : Antioxidants, Hepatoprotective

Additional Keywords : Dose Response

Problem Substances : Acetaminophen, Paracetamol

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Thymol seems to be a promising candidate for topical therapeutic application as antiviral agent for treatment of herpetic infections.Aug 29, 2017

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Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2017 Aug 30 ;63(8):42-47. Epub 2017 Aug 30. PMID: 28886313

Oregano is a Sub of the following Topic

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View the Evidence: 152 Abstracts with Oregano Research

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A spray containing eucalyptus, peppermint, oregano and rosemary improves symptoms of upper respiratory infection.Jan 01, 2011

Carvacrol ameliorates haematological parameters, antioxidant biomarkers and pulmonary function in patients with sulphur mustard-induced lung disorders.Mar 24, 2018

Carvacrol reduced inflammatory cytokine and chemokine while increased anti-inflammatory cytokines in veterans exposed to mustard gas.Mar 31, 2019

Oregano essential oil is effective against insecticide-susceptible and pyrethroid/malathion-resistant head lice.Mar 25, 2009

Possible therapeutic effect of carvacrol on asthmatic patients.Dec 31, 2017

The combination of carvacrol and exercise could be an effective therapeutic tool for treatment of neurobehavioral deficits in Parkinson's disease patients.Jul 28, 2019

Zataria multiflora could be suggested for use against asthma.Oct 31, 2017

A study of in vitro antifungal activity of pure constituents of essentials oils against Candida-associated denture stomatitis. Carvacrol, eugenol, geraniol, linalool and terpinen-4-ol were very active in vitro against oral Candida isolates. Dec 31, 2010

Carvacrol mediates its protective effect through modulation of UVB-induced ROS.Oct 31, 2015

O. majorana and F. vulgare aqueous extracts showed dose and time dependent anti-Blastocystis activity.Mar 31, 2018

The radioprotective effects of Origanum vulgare extract against genotoxicity induced by Radioiodine 131 in human blood lymphocyte.Mar 31, 2013

A combination of chamomile and oregano extracts could form a new class of drugs to treat diabetic complications.Sep 01, 2016

Administration of Zataria multiflora extract and carvacrol could reduce the oxidative damage in the rat liver induced by doxorubicin.Nov 30, 2018

After 6 weeks of supplementation with daily oil of oregano there was complete disappearance of Entamoeba hartmanni , Endolimax nana, and Blastocystis hominis.Apr 30, 2000

An extract of Zataria multiflora and carvacrol had protective effects on the renal damage induced by Adriamycin.Aug 08, 2019

Both curcumin and carvacrol showed a great efficacy against hepatocellular carcinoma.Dec 31, 2014

Carvacrol alleviates ethanol-mediated hippocampal neuronal impairment by antioxidative and antiapoptotic effects.Dec 31, 2016

Carvacrol and pomegranate decrease methotrexate related damage and apoptotic activity in intestinal tissue.Dec 31, 2014

Carvacrol and Zataria multiflora influenced the PPARγ agonist effects on systemic inflammation and oxidative stress induced by inhaled paraquat.Jun 30, 2020

Carvacrol attenuates cyclophosphamide-induced oxidative stress in rat kidney.Feb 02, 2017

Carvacrol attenuates diabetic cardiomyopathy.Dec 31, 2018

Carvacrol attenuates hippocampal neuronal death after global cerebral ischemia.Nov 25, 2018

Carvacrol can be used as a protective agent against benzo(a)pyrene-induced lung toxicity and inflammation.Dec 31, 2016

Carvacrol could potentially be used to control gut dysbiosis and reduce C. difficile infection.Dec 31, 2016

Carvacrol exerted an anti-hyperglycemic effect in streptozotocin-induced diabetes.May 10, 2020

Carvacrol has a hypotensive effect in normotensive rats.Oct 01, 2007

Carvacrol has significant potential as an inhibitor of memory degeneration in neurodegenerative diseases.Dec 31, 2019

Carvacrol may be a promising protective agent against bronchial asthma.Jan 31, 2020

Carvacrol normalizes elevated liver enzymes induced by d-galactosamine-induced hepatotoxicity in rats.Dec 01, 2009

Carvacrol obtained from oregano oil significantly increases the liver regeneration rate in rats undergoing partial hepatectomy. Sep 01, 2007

Carvacrol prevents the proconvulsant effect of LPS possibly through the inhibition of the COX-2 increased activity.Jan 11, 2018

Carvacrol promotes neuroprotection in the mouse hemiparkinsonian model.Jan 24, 2017

Carvacrol protects against 6-hydroxydopamine-induced neurotoxicity in in vivo and in vitro models of Parkinson's disease.Jul 29, 2019

Carvacrol provides protection for hippocampal neurons against cerebral ischemia.Aug 26, 2019

Carvacrol reduces hippocampal cell death and improves learning and memory deficits following lead-induced neurotoxicity via antioxidant activity.Apr 16, 2020

Carvacrol suppresses learning and memory dysfunction and hippocampal damages caused by chronic cerebral hypoperfusion.Dec 31, 2019

Carvacrol suppresses the progression of liver fibrosis.Jan 31, 2019

Chronic treatment with carvacrol improves passive avoidance memory in a rat model of Parkinson's disease.Jan 31, 2018

Co-administration of curcumin or carvacrol and doxorubicin for 24 days could improve the heart function and structural changes.Oct 31, 2019

Cognitive-enhancing activity of thymol and carvacrol in two rat models of dementia.May 31, 2012

Effects of carvacrol on human fibroblast (WS-1) and gastric adenocarcinoma (AGS) cells in vitro and on Wistar rats in vivo.Oct 31, 2018

Evaluation of the antibacterial activity and efflux pump reversal of thymol and carvacrol against Staphylococcus aureus.Apr 29, 2020

O. vulgare extract improved function and structure of testis tissue against finasteride-induced testicular toxicity.Sep 22, 2020

O. vulgare leaf extract has inhibitory effects on paraquat-induced liver damage due to its antioxidant properties.Feb 08, 2018

O. vulgare showed protective activity against carbon tetrachloride-induced hepatotoxicity.Mar 31, 2013

Oregano and cranberry extracts have a prolongevity effect in the Mexican fruit fly. Jan 01, 2010

Oregano and onion controls proliferative enteropathy in weaning pigs. Jan 01, 2009

Oregano leaves administered as an oral solution to calves with diarrhoea may be as effective in the treatment of colibacillosis (E. Coli infection) as neomycin.Oct 01, 1986

Origanum vulgare essential oil is an effective counteractive treatment against cypermethrin-induced damage in exposed common carp.Sep 05, 2020

Origanum vulgare leaf extract protects mice bone marrow cells against ionizing radiation.Oct 31, 2016

Protective effect of carvacrol on acetic acid-induced colitis.Nov 30, 2017

The ameliorative effect of carvacrol on oxidative stress and germ cell apoptosis in testicular tissue of adult diabetic rats.Feb 28, 2019

The results indicated a preventive effect of Z. multiflora extract and its constituent, carvacrol, on tracheal responsiveness and pathological changes of the lung.Apr 30, 2015

The results indicated that carvacrol protected from learning and memory impairment and the brain tissue inflammation and oxidative stress.Mar 31, 2020

The use of Carvacrol as a promising new strategy for the prevention or treatment of Parkinson's disease may be considered.Jan 29, 2018

The Zataria multiflora extract had a potent bactericidal effect against A. baumannii that could downregulate the ompA gene.Jul 23, 2019

Therapeutic potential of Origanum vulgare leaf hydroethanolic extract against renal oxidative stress and nephrotoxicity induced by paraquat.Oct 31, 2019

This study demonstrates a distinct tumour-suppressive effect of oregano in a breast cancer model.Feb 22, 2016

Thyme and its constituents increase the activities of xenobiotic-metabolizing enzymes in mouse liver.Jan 01, 2005

Thymol and carvacrol are highly promising candidates for the development of effective and safe drugs in the fight against visceral leishmaniasis.May 29, 2019

Zataria multiflora and carvacrol have a powerful hepatoprotective effects.Nov 30, 2018

Carvacrol (oregano), geraniol (geranium) and thymol (thyme) have significant anti-Candida activity and contribute to dissolving biofim. Jun 01, 2008

The results of the present study show that the 3 plant-derived essential oils can be used to prepare tomato-based antimicrobial edible films that are effective against Listeria, E. coli, and Salmonella.Sep 01, 2009

A combination of plant extracts could induce antiproliferative and apoptosis in acute myeloid leukemia cells.May 06, 2016

A herbal antifungal formulation of Thymus serpillum, Origanum vulgare and Rosmarinus officinalis for treating ovine dermatophytosis due to Trichophyton mentagrophytes.Apr 30, 2013

A review of dietary plants for the prevention and management of kidney stones.Mar 06, 2018

A review of the antimicrobial activity of basil, oregano, and thyme essential oils.Mar 27, 2017

Anti-biofilm activities of essential oils rich in carvacrol and thymol against Salmonella Enteritidis.Feb 28, 2019

Anti-inflammatory and antioxidant activity of carvacrol in the respiratory system.Apr 05, 2020

Anti-proliferative activity of Origanum vulgare inhibited lipogenesis and induced mitochondrial mediated apoptosis in human stomach cancer cell lines.Nov 30, 2018

Antifungal activity of essential oils against azole-resistant and azole-susceptible vaginal Candida glabrata strains.Sep 30, 2018

Oregano

View the Evidence:
152 Abstracts with Oregano Research