Oregano

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140 Diseases Researched for Oregano
NameACCKFocus
Asthma322Locked
Chemical Weapon Agent Injury: Sulfur Mustard220Locked
Inflammation720Locked
Staphylococcus aureus infection920Locked
Oxidative Stress1019Locked
Parkinson's Disease518Locked
Streptococcus pyogenes 211Locked
C-Reactive Protein110Locked
Candida Infection 610Locked
Chemically-Induced Liver Damage610Locked
Head Lice110Locked
Upper Respiratory Infections110Locked
Lipid Peroxidation38Locked
Diabetic Complications47Locked
Lipopolysaccharide-Induced Toxicity47Locked
Breast Cancer56Locked
Chemotherapy-Induced Toxicity: Doxorubicin36Locked
Pesticide Toxicity 36Locked
Alzheimer's Disease35Locked
Blastocystis hominis infections15Locked
DNA damage15Locked
Hypertension35Locked
Radiation-Induced Illness: Radioiodine (Iodine-131)15Locked
Salmonella Infections55Locked
Acinetobacter baumannii infection34Locked
Brain: Oxidative Stress24Locked
Candidiasis34Locked
Carcinoma: Non-Small-Cell Lung34Locked
Cerebral Ischemia24Locked
Chemotherapy-Induced Kidney Damage24Locked
Clostridium Infections24Locked
Escherichia coli Infections34Locked
Foodborne Pathogens: Prevention/Food Preservation44Locked
Gastric Cancer34Locked
Infection: Antibiotic Resistant34Locked
Leishmaniasis34Locked
Liver Cancer34Locked
Liver Disease14Locked
Memory Disorders24Locked
Paraquat Toxicity24Locked
Prostate Cancer44Locked
Acetaminophen (Tylenol) Toxicity 23Locked
Candida Albicans33Locked
Kidney Damage: Chemically-Induced23Locked
Klebsiella Infections33Locked
Neurodegenerative Diseases23Locked
Rheumatoid Arthritis23Locked
Staphylococcus aureus: Methicillin-resistant (MRSA)23Locked
ALT: Elevated12Locked
Acute Myeloid Leukemia22Locked
Aging12Locked
Alcohol Toxicity 12Locked
Benzo[a]pyrene-induced Toxicity 12Locked
Brain Inflammation 12Locked
Campylobacter Infections12Locked
Cardiac Hypertrophy12Locked
Cardiomyopathy12Locked
Cerebral Hypoperfusion12Locked
Chemotherapy and Radiation Toxicity12Locked
Chemotherapy-Induced Toxicity: Cyclophosphamide12Locked
Chemotherapy-Induced Toxicity: Cisplatin12Locked
Chemotherapy-Induced Toxicity: Paclitaxel12Locked
Cholera12Locked
Chronic Obstructive Pulmonary Disease12Locked
Cognitive Decline/Dysfunction12Locked
Colitis12Locked
Colon Cancer22Locked
Coxsackievirus Infections22Locked
Dementia12Locked
Dental Caries12Locked
Diabetes Mellitus: Type 112Locked
Diabetes Mellitus: Type 212Locked
Diabetes: Sexual Dysfunction/Reproduction12Locked
Drug-Induced Toxicity: Methotrexate12Locked
Dysbiosis12Locked
Enteropathy12Locked
Fungal Infection22Locked
Gamma-glutamyl transpeptidase: Elevated12Locked
Gram-Negative Bacterial Infections22Locked
HIV Infections12Locked
Herpes Simplex Virus Type 122Locked
Hyperglycemia12Locked
Hypoglycemia22Locked
Influenza A12Locked
Lead Poisoning12Locked
Learning disorders12Locked
Liver Damage12Locked
Liver Damage: Drug-Induced12Locked
Liver Fibrosis12Locked
Mycobacterium Avium 12Locked
Mycobacterium Infections12Locked
Mycobacterium Tuberculosis22Locked
Parasitic Intestinal Diseases12Locked
Pesticide Toxicity: Cypermethrin12Locked
Pseudomonas aeruginosa22Locked
Seizures12Locked
Staphylococcal Infections22Locked
Steptococcus Mutans Infections12Locked
Streptococcus Infections22Locked
Testicular Injury: Chemical/Metal Induced12Locked
Xenobiotic Exposures12Locked
Aluminum Toxicity 11Locked
Bacterial Infections and Mycoses11Locked
Breast Cancer: Triple Negative 11Locked
Cadmium Poisoning 11Locked
Cancers: Drug Resistant11Locked
Candida Glabrata11Locked
Candidiasis: Vulvovaginal11Locked
Cervical Cancer11Locked
Cholesterol: Oxidation11Locked
Choriocarcinoma11Locked
Coronavirus Infection11Locked
Cystic Fibrosis: Infections11Locked
Denture Stomatitis11Locked
Dermatophytoses11Locked
Fungal Infections: Biofilm Formation/Resistance11Locked
Giardiasis11Locked
Glioblastoma11Locked
Herpes Simplex Virus Type 211Locked
Influenza11Locked
Kidney Stones11Locked
Listeria Infections11Locked
Lung Cancer11Locked
Lyme Disease11Locked
Metabolic Syndrome X11Locked
Multiple Sclerosis11Locked
Osteoarthritis11Locked
Periodontitis11Locked
Proteus Vulgaris Infections11Locked
Protozoan Infections11Locked
Radiotherapy11Locked
Respiratory Infections11Locked
Respiratory Syncytial Virus Infections11Locked
Rhinovirus Infection 11Locked
Sepsis11Locked
Staphylococcus epidermidis11Locked
Trichophytosis11Locked
Tuberculosis11Locked
Vibrio Infections11Locked
Wound Healing11Locked
70 Pharmacological Actions Researched for Oregano
NameACCKFocus
Anti-Inflammatory Agents2868Locked
Antioxidants3066Locked
Anti-Bacterial Agents3046Locked
Neuroprotective Agents1738Locked
Antiproliferative 1720Locked
Antifungal Agents1116Locked
Antimicrobial1516Locked
Apoptotic1316Locked
Hepatoprotective1016Locked
Chemoprotective Agents714Locked
Gastrointestinal Agents414Locked
Anti-Apoptotic713Locked
Renoprotective611Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor711Locked
Anti-Asthmatic Agents110Locked
Antiviral Agents79Locked
Radioprotective38Locked
Antiparasitic Agents27Locked
Interleukin-1 beta downregulation67Locked
Malondialdehyde Down-regulation47Locked
Cardioprotective36Locked
Hypoglycemic Agents46Locked
Antihypertensive Agents35Locked
Cyclooxygenase 2 Inhibitors35Locked
Interleukin-4 downregulation35Locked
Interleukin-6 Downregulation55Locked
NF-kappaB Inhibitor35Locked
Photoprotective15Locked
Cell cycle arrest44Locked
Immunomodulatory24Locked
Interleukin-5 downregulation24Locked
Leishmanicidal34Locked
Anti-metastatic33Locked
Chemopreventive33Locked
Chemotherapeutic33Locked
Cytotoxic23Locked
Interferon Gamma Reducer23Locked
Interleukin-12 downregulation23Locked
Prophylactic Agents23Locked
Quorum Sensing Inhibition33Locked
Alpha-amylase inhibitor12Locked
Angiogenesis Inhibitors12Locked
Anti-Fibrotic12Locked
Bcl-xL down-regulation12Locked
Cholinesterase Inhibitors12Locked
Gastroprotective12Locked
Hypolipidemic12Locked
Interleukin-10 upregulation22Locked
Interleukin-17 downregulation12Locked
Interleukin-2 Downregulation12Locked
Interleukin-8 downregulation22Locked
Nitric Oxide Inhibitor12Locked
Phase I Detoxification Enzyme Inducer12Locked
Phase II Detoxification Enzyme Inducer12Locked
Superoxide Dismutase Up-regulation12Locked
interleukin-13 down-regulation12Locked
Acetylcholinesterase Inhibitor11Locked
Alpha-glucosidase inhibitor 11Locked
Antineoplastic Agents11Locked
Antiprotozoal Agents11Locked
Autophagy Inhibitors11Locked
Bax/Bcl2 Ratio: Decrease11Locked
Enzyme Inhibitors11Locked
Heat Shock Protein Down-Regulation11Locked
Matrix Metalloproteinase-13 (MMP-13) Inhibitor11Locked
Matrix metalloproteinase-3 (MMP-3) inhibitor11Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor11Locked
Nrf2 activation11Locked
STAT3 Inhibitor11Locked
Vasodilator Agents11Locked
Related Topics

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View the Evidence:
236 Abstracts with Oregano Research

[+]

A spray containing eucalyptus, peppermint, oregano and rosemary improves symptoms of upper respiratory infection.Jan 01, 2011

Pubmed Data : Evid Based Complement Alternat Med. 2011;2011:690346. Epub 2010 Nov 1. PMID: 21052500
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Substances : Eucalyptus, Oregano, Peppermint, Rosemary
Diseases : Upper Respiratory Infections
[+]

Carvacrol ameliorates haematological parameters, antioxidant biomarkers and pulmonary function in patients with sulphur mustard-induced lung disorders.Mar 24, 2018

Pubmed Data : J Clin Pharm Ther. 2018 Mar 25. Epub 2018 Mar 25. PMID: 29574804
Article Published Date : Mar 24, 2018
Study Type : Human Study
Additional Links
Substances : Carvacrol
Diseases : Chemical Weapon Agent Injury: Sulfur Mustard
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Problem Substances : Mustard Gas
[+]

Carvacrol reduced inflammatory cytokine and chemokine while increased anti-inflammatory cytokines in veterans exposed to mustard gas.Mar 31, 2019

Pubmed Data : Respir Med. 2019 Apr ;150:21-29. Epub 2019 Feb 5. PMID: 30961947
Article Published Date : Mar 31, 2019
Study Type : Human Study
Additional Links
Substances : Carvacrol
Diseases : Chemical Weapon Agent Injury: Sulfur Mustard, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Problem Substances : Mustard Gas
[+]

Essential oil of Origanum vulgare may exhibit an antibacterial effect, similar to the antibiotic treatment, without promoting MS-specific dysbiosis.Jan 07, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2021 Jan 8 ;26(2). Epub 2021 Jan 8. PMID: 33429991
Article Published Date : Jan 07, 2021
Study Type : Human Study
Additional Links
Substances : Oregano
Diseases : Staphylococcus aureus infection, Streptococcus pyogenes
Pharmacological Actions : Anti-Bacterial Agents, Gastrointestinal Agents
[+]

Oregano essential oil is effective against insecticide-susceptible and pyrethroid/malathion-resistant head lice.Mar 25, 2009

Pubmed Data : J Agric Food Chem. 2009 Mar 25;57(6):2282-7. PMID: 19292466
Article Published Date : Mar 25, 2009
Study Type : Human Study
Additional Links
Substances : Oregano
Diseases : Head Lice
Additional Keywords : Malathion Resistance, Natural Substances Versus Drugs, Pyrethroid Resistance
[+]

Possible therapeutic effect of carvacrol on asthmatic patients.Dec 31, 2017

Pubmed Data : Phytother Res. 2018 Jan ;32(1):151-159. Epub 2017 Nov 28. PMID: 29193478
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Carvacrol
Diseases : Asthma, C-Reactive Protein
Pharmacological Actions : Anti-Inflammatory Agents
[+]

The combination of carvacrol and exercise could be an effective therapeutic tool for treatment of neurobehavioral deficits in Parkinson's disease patients.Jul 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arq Neuropsiquiatr. 2019 Jul 29 ;77(7):493-500. Epub 2019 Jul 29. PMID: 31365641
Article Published Date : Jul 28, 2019
Study Type : Human Study
Additional Links
Substances : Carvacrol
Diseases : Parkinson's Disease
Therapeutic Actions : Exercise
Pharmacological Actions : Neuroprotective Agents
[+]

Zataria multiflora could be suggested for use against asthma.Oct 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2017 Nov-Dec;7(6):531-541. PMID: 29299436
Article Published Date : Oct 31, 2017
Study Type : Human Study
Additional Links
Substances : Carvacrol, Zataria multiflora
Diseases : Asthma
Pharmacological Actions : Anti-Asthmatic Agents
[+]

A study of in vitro antifungal activity of pure constituents of essentials oils against Candida-associated denture stomatitis. Carvacrol, eugenol, geraniol, linalool and terpinen-4-ol were very active in vitro against oral Candida isolates. Dec 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2011 ;11:119. Epub 2011 Nov 26. PMID: 22118215
Article Published Date : Dec 31, 2010
Study Type : Human In Vitro
Additional Links
Substances : Carvacrol, Essential Oils: Unspecified, Eugenol, Geraniol
Diseases : Candida Infection
Pharmacological Actions : Antifungal Agents
Additional Keywords : Dental, Plant Extracts
[+]

Carvacrol mediates its protective effect through modulation of UVB-induced ROS.Oct 31, 2015

Pubmed Data : J Biochem Mol Toxicol. 2015 Nov ;29(11):497-507. Epub 2010 May 21. PMID: 26768646
Article Published Date : Oct 31, 2015
Study Type : Human In Vitro
Additional Links
Substances : Carvacrol
Diseases : DNA damage, Lipid Peroxidation, Oxidative Stress
Therapeutic Actions : Sunlight exposure
Pharmacological Actions : Antioxidants, Photoprotective
[+]

O. majorana and F. vulgare aqueous extracts showed dose and time dependent anti-Blastocystis activity.Mar 31, 2018

Pubmed Data : Phytomedicine. 2018 Apr 1 ;43:158-163. Epub 2018 Apr 10. PMID: 29747749
Article Published Date : Mar 31, 2018
Study Type : Human In Vitro
Additional Links
Substances : Fennel, Flavonoids, Oregano
Diseases : Blastocystis hominis infections
Pharmacological Actions : Antioxidants, Antiparasitic Agents
Additional Keywords : Natural Substances Versus Drugs, Plant Extracts
[+]

The radioprotective effects of Origanum vulgare extract against genotoxicity induced by Radioiodine 131 in human blood lymphocyte.Mar 31, 2013

Pubmed Data : Cancer Biother Radiopharm. 2013 Apr ;28(3):201-6. Epub 2013 Feb 15. PMID: 23413802
Article Published Date : Mar 31, 2013
Study Type : Human In Vitro
Additional Links
Substances : Oregano
Diseases : Radiation-Induced Illness: Radioiodine (Iodine-131)
Pharmacological Actions : Antioxidants, Radioprotective
Additional Keywords : Plant Extracts
[+]

The results revealed the antifungal activity of oregano. Mar 26, 2023

Pubmed Data : Microbiol Spectr. 2023 Mar 27 ;11(2):e0512422. Epub 2023 Mar 27. PMID: 36971589
Article Published Date : Mar 26, 2023
Study Type : Human In Vitro
Additional Links
Substances : Oregano
Pharmacological Actions : Antifungal Agents
[+]

Anti-inflammatory activity of carvacrol protects the heart from lipopolysaccharide-induced cardiac dysfunction.Jun 30, 2023

Pubmed Data : Life Sci. 2023 Jul 1 ;324:121743. Epub 2023 Apr 27. PMID: 37120013
Article Published Date : Jun 30, 2023
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Cardioprotective, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

Antinociceptive, anti-inflammatory, and cytotoxic properties of Origanum vulgare essential oil.Mar 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Korean J Pain. 2022 Apr 1 ;35(2):140-151. PMID: 35354677
Article Published Date : Mar 31, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Beta-Caryophyllene, Oregano
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antinoceceptive
Additional Keywords : Essential Oils
[+]

A combination of chamomile and oregano extracts could form a new class of drugs to treat diabetic complications.Sep 01, 2016

Pubmed Data : Can J Physiol Pharmacol. 2016 Sep 2:1-9. Epub 2016 Sep 2. PMID: 27875075
Article Published Date : Sep 01, 2016
Study Type : Animal Study
Additional Links
Substances : Chamomile, Oregano
Diseases : Diabetic Complications
Pharmacological Actions : Alpha-amylase inhibitor, Anti-Apoptotic, Hypoglycemic Agents, Hypolipidemic
Additional Keywords : Natural Substance Synergy, Plant Extracts
Problem Substances : Alloxan
[+]

Administration of Zataria multiflora extract and carvacrol could reduce the oxidative damage in the rat liver induced by doxorubicin.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed J. 2018 Dec ;41(6):340-347. Epub 2019 Jan 11. PMID: 30709575
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Zataria multiflora
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin, Liver Damage: Drug-Induced
Pharmacological Actions : Chemoprotective Agents, Hepatoprotective
[+]

After 6 weeks of supplementation with daily oil of oregano there was complete disappearance of Entamoeba hartmanni , Endolimax nana, and Blastocystis hominis.Apr 30, 2000

Pubmed Data : Phytother Res. 2000 May ;14(3):213-4. PMID: 10815019
Article Published Date : Apr 30, 2000
Study Type : Animal Study
Additional Links
Substances : Oregano
Diseases : Parasitic Intestinal Diseases
Pharmacological Actions : Antiparasitic Agents
Additional Keywords : Significant Treatment Outcome
[+]

An extract of Zataria multiflora and carvacrol had protective effects on the renal damage induced by Adriamycin.Aug 08, 2019

Pubmed Data : Arch Physiol Biochem. 2019 Aug 9:1-9. Epub 2019 Aug 9. PMID: 31397187
Article Published Date : Aug 08, 2019
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Zataria multiflora
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Antioxidants, Chemoprotective Agents, Malondialdehyde Down-regulation, Renoprotective
[+]

Both curcumin and carvacrol showed a great efficacy against hepatocellular carcinoma.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2015 ;16(12):4949-54. PMID: 26163620
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Curcumin
Diseases : Liver Cancer
Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative , Apoptotic
Additional Keywords : Gene Expression Regulation
[+]

Carvacrol administration may have therapeutic potential after traumatic brain injury.Nov 09, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 Nov 10 ;23(22). Epub 2022 Nov 10. PMID: 36430333
Article Published Date : Nov 09, 2022
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Traumatic Brain Injury
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Carvacrol alleviates ethanol-mediated hippocampal neuronal impairment by antioxidative and antiapoptotic effects.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2017 ;2017:4079425. Epub 2017 Jan 16. PMID: 28191274
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Alcohol Toxicity , Cognitive Decline/Dysfunction, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
[+]

Carvacrol and pomegranate decrease methotrexate related damage and apoptotic activity in intestinal tissue.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Clin Exp Med. 2015;8(9):15474-15481. Epub 2015 Sep 15. PMID: 26629037
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Pomegranate
Diseases : Drug-Induced Toxicity: Methotrexate
Pharmacological Actions : Anti-Apoptotic, Gastroprotective
[+]

Carvacrol and Zataria multiflora influenced the PPARγ agonist effects on systemic inflammation and oxidative stress induced by inhaled paraquat.Jun 30, 2020

Pubmed Data : Iran J Basic Med Sci. 2020 Jul ;23(7):930-936. PMID: 32774816
Article Published Date : Jun 30, 2020
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Zataria multiflora
Diseases : Inflammation, Oxidative Stress, Paraquat Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Problem Substances : Paraquat
[+]

Carvacrol at high doses can reduce the harmful effects of cisplatin on the ovary and improve ovarian reserve.Feb 28, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Taiwan J Obstet Gynecol. 2023 Mar ;62(2):256-263. PMID: 36965892
Article Published Date : Feb 28, 2023
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Ovarian Failure
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents, Fertility Agents: Female
[+]

Carvacrol attenuated lipopolysaccharide-induced intestinal injury.Jul 14, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2023 Jul 15 ;13(1):11447. Epub 2023 Jul 15. PMID: 37454126
Article Published Date : Jul 14, 2023
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Carvacrol attenuated neuroinflammation, oxidative stress and depression and anxiety like behaviors.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2022 ;12(5):514-526. PMID: 36249457
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Anxiety, Brain Inflammation , Depression
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
[+]

Carvacrol attenuates cyclophosphamide-induced oxidative stress in rat kidney.Feb 02, 2017

Pubmed Data : Can J Physiol Pharmacol. 2017 Feb 3. Epub 2017 Feb 3. PMID: 28177660
Article Published Date : Feb 02, 2017
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions : Chemoprotective Agents, Renoprotective
[+]

Carvacrol attenuates diabetic cardiomyopathy.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:998. Epub 2019 Sep 12. PMID: 31572181
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Cardiomyopathy
Pharmacological Actions : Cardioprotective
Additional Keywords : Natural Substances Versus Drugs
[+]

Carvacrol attenuates hippocampal neuronal death after global cerebral ischemia.Nov 25, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cells. 2018 Nov 26 ;7(12). Epub 2018 Nov 26. PMID: 30486272
Article Published Date : Nov 25, 2018
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Cerebral Ischemia
Pharmacological Actions : Neuroprotective Agents
[+]

Carvacrol can be used as a protective agent against benzo(a)pyrene-induced lung toxicity and inflammation.Dec 31, 2016

Pubmed Data : Hum Exp Toxicol. 2017 Jan 1:960327117735572. Epub 2017 Jan 1. PMID: 29019276
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Benzo[a]pyrene-induced Toxicity , Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor
Problem Substances : Benzo(a)pyrene
[+]

Carvacrol could potentially be used to control gut dysbiosis and reduce C. difficile infection.Dec 31, 2016

Pubmed Data : Front Microbiol. 2017 ;8:625. Epub 2017 Apr 21. PMID: 28484429
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Clostridium Infections, Dysbiosis
Pharmacological Actions : Gastrointestinal Agents
[+]

Carvacrol decreases blood-brain barrier permeability post-diffuse traumatic brain injury.Sep 03, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2023 Sep 4 ;13(1):14546. Epub 2023 Sep 4. PMID: 37666857
Article Published Date : Sep 03, 2023
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Antioxidants, Matrix metalloproteinase-9 (MMP-9) inhibitor, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Carvacrol decreases hypertrophy markers in in-vivo and in-vitro models of hypertrophy.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Pharm Res. 2019 ;18(3):1380-1394. PMID: 32641948
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Cardiac Hypertrophy
Pharmacological Actions : Cardioprotective
[+]

Carvacrol enhances anti-tumor activity and mitigates cardiotoxicity of sorafenib in thioacetamide-induced hepatocellular carcinoma.Jun 30, 2023

Pubmed Data : Life Sci. 2023 Jul 1 ;324:121735. Epub 2023 May 2. PMID: 37142088
Article Published Date : Jun 30, 2023
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Liver Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Cardioprotective, Chemoprotective Agents, Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Sorafenib
[+]

Carvacrol exerted an anti-hyperglycemic effect in streptozotocin-induced diabetes.May 10, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Med Ther. 2020 May 11 ;20(1):142. Epub 2020 May 11. PMID: 32393384
Article Published Date : May 10, 2020
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Diabetes Mellitus: Type 1, Hyperglycemia
Pharmacological Actions : Hypoglycemic Agents
[+]

Carvacrol exerts anti-inflammatory, anti-oxidative stress and hepatoprotective effects against diclofenac-induced liver injury.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Prev Med. 2023 ;14:61. Epub 2023 May 27. PMID: 37351047
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Liver Damage: Drug-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective
Problem Substances : Diclofenac
[+]

Carvacrol has a hypotensive effect in normotensive rats.Oct 01, 2007

Pubmed Data : Planta Med. 2007 Oct;73(13):1365-71. Epub 2007 Oct 9. PMID: 17924312
Article Published Date : Oct 01, 2007
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents
[+]

Carvacrol has significant potential as an inhibitor of memory degeneration in neurodegenerative diseases.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Korean J Physiol Pharmacol. 2020 Jan ;24(1):27-37. Epub 2020 Dec 20. PMID: 31908572
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Memory Disorders, Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

Carvacrol improves vascular function in hypertensive animals.Jul 03, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2023 Jul 4 ;15(13). Epub 2023 Jul 4. PMID: 37447358
Article Published Date : Jul 03, 2023
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Hypertension
Pharmacological Actions : Vasoprotective
[+]

Carvacrol may alleviate vascular inflammation in diabetic db/db mice.Aug 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2020 Sep ;46(3):977-988. Epub 2020 Jun 19. PMID: 32583003
Article Published Date : Aug 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Diabetes Mellitus: Type 2, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Carvacrol may be a promising protective agent against bronchial asthma.Jan 31, 2020

Pubmed Data : Life Sci. 2020 Feb 1 ;242:117222. Epub 2019 Dec 24. PMID: 31881223
Article Published Date : Jan 31, 2020
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Asthma
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, interleukin-13 down-regulation, Interleukin-4 downregulation, Interleukin-5 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Carvacrol may be a promising protective agent in λ-Cyhalothrin-induced hepatotoxicity and nephrotoxicity.Jun 30, 2023

Pubmed Data : Environ Toxicol. 2023 Jul ;38(7):1535-1547. Epub 2023 Mar 22. PMID: 36947485
Article Published Date : Jun 30, 2023
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Chemically-Induced Liver Damage, Inflammation, Kidney Damage: Chemically-Induced, Oxidative Stress, Pesticide Toxicity
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Renoprotective
Problem Substances : Pesticides
[+]

Carvacrol mitigates vancomycin-induced nephrotoxicity.Nov 30, 2022

Pubmed Data : Eur Rev Med Pharmacol Sci. 2022 Dec ;26(23):8738-8755. PMID: 36524493
Article Published Date : Nov 30, 2022
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Kidney Damage: Chemically-Induced, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, NF-kappaB Inhibitor, Nrf2 activation, Renoprotective
Additional Keywords : Drug: Vancomycin
Problem Substances : Vancomycin
[+]

Carvacrol normalizes elevated liver enzymes induced by d-galactosamine-induced hepatotoxicity in rats.Dec 01, 2009

Pubmed Data : Fundam Clin Pharmacol. 2009 Dec;23(6):757-65. Epub 2009 Jul 24. PMID: 19650854
Article Published Date : Dec 01, 2009
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : ALT: Elevated, Chemically-Induced Liver Damage, Gamma-glutamyl transpeptidase: Elevated, Oxidative Stress
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

Carvacrol obtained from oregano oil significantly increases the liver regeneration rate in rats undergoing partial hepatectomy. Sep 01, 2007

Pubmed Data : Toxicol Sci. 2007 Sep;99(1):190-202. Epub 2007 Mar 30. PMID: 17689059
Article Published Date : Sep 01, 2007
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Oregano
Diseases : Liver Disease
Additional Keywords : Liver Regeneration, Regenerative Substances
[+]

Carvacrol prevents acrylamide-induced oxidative and inflammatory liver damage and dysfunction.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2023 ;14:1161448. Epub 2023 Apr 5. PMID: 37089925
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Acrylamide-induced toxicity, Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Acrylamide
[+]

Carvacrol prevents the proconvulsant effect of LPS possibly through the inhibition of the COX-2 increased activity.Jan 11, 2018

Pubmed Data : Metab Brain Dis. 2018 12 ;33(6):2045-2050. Epub 2018 Sep 18. PMID: 30229386
Article Published Date : Jan 11, 2018
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Lipopolysaccharide-Induced Toxicity, Seizures
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors
[+]

Carvacrol promotes neuroprotection in the mouse hemiparkinsonian model.Jan 24, 2017

Pubmed Data : Neuroscience. 2017 07 25 ;356:176-181. Epub 2017 May 17. PMID: 28526576
Article Published Date : Jan 24, 2017
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Carvacrol protects against 6-hydroxydopamine-induced neurotoxicity in in vivo and in vitro models of Parkinson's disease.Jul 29, 2019

Pubmed Data : Neurotox Res. 2019 Jul 30. Epub 2019 Jul 30. PMID: 31364033
Article Published Date : Jul 29, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Parkinson's Disease
Pharmacological Actions : Malondialdehyde Down-regulation, Neuroprotective Agents
[+]

Carvacrol protects rat liver exposed to formaldehyde by regulating oxidative stress, and asprosin and subfatin hormones.Oct 31, 2023

Pubmed Data : Biotech Histochem. 2023 Nov ;98(5):336-345. Epub 2023 Mar 13. PMID: 36912062
Article Published Date : Oct 31, 2023
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Chemically-Induced Liver Damage, Formaldehyde Toxicity, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Hepatoprotective
Problem Substances : Formaldehyde
[+]

Carvacrol provides protection for hippocampal neurons against cerebral ischemia.Aug 26, 2019

Pubmed Data : Life Sci. 2019 Aug 27:116795. Epub 2019 Aug 27. PMID: 31470002
Article Published Date : Aug 26, 2019
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Cerebral Ischemia
Pharmacological Actions : Neuroprotective Agents
[+]

Carvacrol reduced pathological and biochemical damage, and improved kidney function by lowering the serum urea level.Nov 28, 2022

Pubmed Data : Biotech Histochem. 2022 Nov 29:1-8. Epub 2022 Nov 29. PMID: 36444536
Article Published Date : Nov 28, 2022
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Nephrolithiasis
Pharmacological Actions : Renoprotective
[+]

Carvacrol reduces hippocampal cell death and improves learning and memory deficits following lead-induced neurotoxicity via antioxidant activity.Apr 16, 2020

Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2020 Apr 17. Epub 2020 Apr 17. PMID: 32303785
Article Published Date : Apr 16, 2020
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Brain: Oxidative Stress, Lead Poisoning
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Problem Substances : Lead
[+]

Carvacrol suppresses learning and memory dysfunction and hippocampal damages caused by chronic cerebral hypoperfusion.Dec 31, 2019

Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2020 04 ;393(4):581-589. Epub 2019 Nov 15. PMID: 31729545
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Cerebral Hypoperfusion
Pharmacological Actions : Neuroprotective Agents
[+]

Carvacrol suppresses the progression of liver fibrosis.Jan 31, 2019

Pubmed Data : Immunopharmacol Immunotoxicol. 2019 Feb ;41(1):163-171. Epub 2019 Feb 1. PMID: 30706740
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Chemically-Induced Liver Damage, Liver Fibrosis
Pharmacological Actions : Anti-Fibrotic, Hepatoprotective
[+]

Carvacrol targets SarA and CrtM of methicillin-resistant Staphylococcus aureus to mitigate biofilm formation and staphyloxanthin synthesis.Dec 07, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ACS Omega. 2020 Dec 8 ;5(48):31100-31114. Epub 2020 Nov 24. PMID: 33324819
Article Published Date : Dec 07, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Staphylococcus aureus: Methicillin-resistant (MRSA)
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation
[+]

Chronic treatment with carvacrol improves passive avoidance memory in a rat model of Parkinson's disease.Jan 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arq Neuropsiquiatr. 2018 Feb ;76(2):71-77. PMID: 29489959
Article Published Date : Jan 31, 2018
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Co-administration of curcumin or carvacrol and doxorubicin for 24 days could improve the heart function and structural changes.Oct 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2019 Nov ;7(11):3581-3588. Epub 2019 Sep 10. PMID: 31763008
Article Published Date : Oct 31, 2019
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Curcumin
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Cardioprotective, Chemoprotective Agents
[+]

Cognitive-enhancing activity of thymol and carvacrol in two rat models of dementia.May 31, 2012

Pubmed Data : Behav Pharmacol. 2012 Jun ;23(3):241-9. PMID: 22470103
Article Published Date : May 31, 2012
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Alzheimer's Disease, Dementia
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cholinesterase Inhibitors
[+]

Combined carvacrol and cilostazol ameliorate ethanol-induced liver fibrosis.Jan 26, 2023

Pubmed Data : Int Immunopharmacol. 2023 Jan 27 ;116:109750. Epub 2023 Jan 27. PMID: 36709594
Article Published Date : Jan 26, 2023
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Alcoholic Liver Disease, Liver Fibrosis
Pharmacological Actions : Anti-Fibrotic, Hepatoprotective
[+]

Effect of carvacrol on histological analysis and expression of genes involved in an animal model of multiple sclerosis.Dec 15, 2022

Pubmed Data : Mult Scler Relat Disord. 2022 Dec 16 ;70:104471. Epub 2022 Dec 16. PMID: 36580874
Article Published Date : Dec 15, 2022
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation
Additional Keywords : Gene Expression Regulation
[+]

Effect of treatment with carvacrol and aerobic training on cardiovascular function in spontaneously hypertensive rats.Feb 16, 2021

Pubmed Data : Exp Physiol. 2021 Feb 17. Epub 2021 Feb 17. PMID: 33595154
Article Published Date : Feb 16, 2021
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Hypertension
Therapeutic Actions : Exercise: Aerobic
Pharmacological Actions : Antihypertensive Agents
[+]

Effects of carvacrol on human fibroblast (WS-1) and gastric adenocarcinoma (AGS) cells in vitro and on Wistar rats in vivo.Oct 31, 2018

Pubmed Data : Mol Cell Biochem. 2018 Nov ;448(1-2):237-249. Epub 2018 Feb 13. PMID: 29442269
Article Published Date : Oct 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Gastric Cancer
Pharmacological Actions : Apoptotic, Cytotoxic
[+]

Eugenol and carvacrol attenuate brain D-galactose-induced aging-related oxidative alterations.Feb 18, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Sci Pollut Res Int. 2022 Feb 19. Epub 2022 Feb 19. PMID: 35182345
Article Published Date : Feb 18, 2022
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Eugenol
Diseases : Aging
Pharmacological Actions : Antioxidants
[+]

Evaluation of the antibacterial activity and efflux pump reversal of thymol and carvacrol against Staphylococcus aureus.Apr 29, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Apr 30 ;25(9). Epub 2020 Apr 30. PMID: 32365898
Article Published Date : Apr 29, 2020
Study Type : Insect Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents
[+]

Memory-enhancing effects of Origanum majorana essential oil in an Alzheimer's.Sep 25, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2020 Sep 26 ;9(10). Epub 2020 Sep 26. PMID: 32993114
Article Published Date : Sep 25, 2020
Study Type : Animal Study
Additional Links
Substances : Oregano
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Neuroprotective effects of carvacrol against cadmium-induced neurotoxicity.Mar 31, 2022

Pubmed Data : Metab Brain Dis. 2022 Apr ;37(4):1259-1269. Epub 2022 Mar 22. PMID: 35316447
Article Published Date : Mar 31, 2022
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Cadmium Poisoning , Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Cadmium
[+]

O. vulgare extract improved function and structure of testis tissue against finasteride-induced testicular toxicity.Sep 22, 2020

Pubmed Data : Andrologia. 2020 Sep 23:e13823. Epub 2020 Sep 23. PMID: 32966695
Article Published Date : Sep 22, 2020
Study Type : Animal Study
Additional Links
Substances : Oregano
Diseases : Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Anti-Apoptotic
[+]

O. vulgare leaf extract has inhibitory effects on paraquat-induced liver damage due to its antioxidant properties.Feb 08, 2018

Pubmed Data : Arch Physiol Biochem. 2018 Feb 9:1-8. Epub 2018 Feb 9. PMID: 29425067
Article Published Date : Feb 08, 2018
Study Type : Animal Study
Additional Links
Substances : Oregano
Diseases : Chemically-Induced Liver Damage, Pesticide Toxicity
Pharmacological Actions : Antioxidants, Hepatoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

O. vulgare showed protective activity against carbon tetrachloride-induced hepatotoxicity.Mar 31, 2013

Pubmed Data : Protoplasma. 2013 Apr ;250(2):483-93. Epub 2012 Jul 7. PMID: 22772591
Article Published Date : Mar 31, 2013
Study Type : Animal Study
Additional Links
Substances : Oregano
Diseases : Chemically-Induced Liver Damage, Lipid Peroxidation
Pharmacological Actions : Antioxidants, Hepatoprotective, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
[+]

Oregano and cranberry extracts have a prolongevity effect in the Mexican fruit fly. Jan 01, 2010

Pubmed Data : J Gerontol A Biol Sci Med Sci. 2010 Jan;65(1):41-50. Epub 2009 Nov 11. PMID: 19906819
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Cranberry, Oregano
Diseases : Aging
Additional Keywords : Plant Extracts
[+]

Oregano and onion controls proliferative enteropathy in weaning pigs. Jan 01, 2009

Pubmed Data : Pol J Vet Sci. 2009;12(3):407-14. PMID: 19886265
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Garlic, Oregano
Diseases : Enteropathy
Additional Keywords : Plant Extracts
[+]

Oregano leaves administered as an oral solution to calves with diarrhoea may be as effective in the treatment of colibacillosis (E. Coli infection) as neomycin.Oct 01, 1986

Pubmed Data : J Ethnopharmacol. 1986 Oct;18(1):33-44. PMID: 16533332
Article Published Date : Oct 01, 1986
Study Type : Animal Study
Additional Links
Substances : Oregano
Diseases : Escherichia coli Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Natural Substances Versus Drugs
[+]

Origanum majorana L. protects against neuroinflammation-mediated cognitive impairment.May 19, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Med Ther. 2023 May 20 ;23(1):165. Epub 2023 May 20. PMID: 37210483
Article Published Date : May 19, 2023
Study Type : Animal Study
Additional Links
Substances : Oregano
Diseases : Cognitive Decline/Dysfunction, Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Neuroprotective Agents
[+]

Origanum vulgare essential oil is an effective counteractive treatment against cypermethrin-induced damage in exposed common carp.Sep 05, 2020

Pubmed Data : Aquat Toxicol. 2020 Sep 6 ;228:105624. Epub 2020 Sep 6. PMID: 32947072
Article Published Date : Sep 05, 2020
Study Type : Animal Study
Additional Links
Substances : Oregano
Diseases : Pesticide Toxicity: Cypermethrin
Pharmacological Actions : Antioxidants
[+]

Origanum vulgare leaf extract protects mice bone marrow cells against ionizing radiation.Oct 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2016 Nov-Dec;6(6):678-685. PMID: 28078248
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Oregano
Diseases : Chemotherapy and Radiation Toxicity
Pharmacological Actions : Radioprotective
Additional Keywords : Plant Extracts
Anti Therapeutic Actions : Low Dose Ionizing Radiation
[+]

Paraquat-induced systemic inflammation and increased oxidative markers in rats improved by Zataria multiflora extract and carvacrol.Aug 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2020 Sep-Oct;10(5):513-522. PMID: 32995329
Article Published Date : Aug 31, 2020
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Zataria multiflora
Diseases : Inflammation, Pesticide Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Problem Substances : Paraquat
[+]

Protective effect of carvacrol against paclitaxel-induced ototoxicity. Nov 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Turk Arch Otorhinolaryngol. 2020 Dec ;58(4):241-248. Epub 2020 Dec 1. PMID: 33554199
Article Published Date : Nov 30, 2020
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Chemoprotective Agents
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Protective effect of carvacrol on acetic acid-induced colitis.Nov 30, 2017

Pubmed Data : Biomed Pharmacother. 2017 Dec ;96:313-319. Epub 2017 Oct 7. PMID: 29017143
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Colitis, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Protective effects of carvacrol against diabetes-induced reproductive damage.Nov 25, 2020

Pubmed Data : Andrologia. 2020 Nov 26:e13899. Epub 2020 Nov 26. PMID: 33242925
Article Published Date : Nov 25, 2020
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Diabetes: Sexual Dysfunction/Reproduction, Diabetic Complications
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents
[+]

The ameliorative effect of carvacrol on oxidative stress and germ cell apoptosis in testicular tissue of adult diabetic rats.Feb 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Mar ;111:568-578. Epub 2018 Dec 29. PMID: 30597310
Article Published Date : Feb 28, 2019
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Diabetic Complications
Pharmacological Actions : Anti-Apoptotic, Antioxidants
[+]

The comparison of the effect of Origanum vulgare L. extract and vitamin C on the gentamycin-induced nephrotoxicity.Mar 09, 2021

Pubmed Data : Drug Chem Toxicol. 2021 Mar 10:1-8. Epub 2021 Mar 10. PMID: 33715559
Article Published Date : Mar 09, 2021
Study Type : Animal Study
Additional Links
Substances : Oregano, Vitamin C
Diseases : Chemotherapy-Induced Kidney Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents, Renoprotective
[+]

The effects of carvacrol on transient receptor potential (TRP) channels in an animal model of Parkinson's disease.Jul 14, 2023

Pubmed Data : Neurotox Res. 2023 Jul 15. Epub 2023 Jul 15. PMID: 37452911
Article Published Date : Jul 14, 2023
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

The protective effect of carvacrol on bevacizumab-related skin injury in rats: a biochemical and histopathological evaluation.Nov 30, 2022

Pubmed Data : Cutan Ocul Toxicol. 2022 Dec ;41(4):285-290. Epub 2022 Sep 21. PMID: 36111398
Article Published Date : Nov 30, 2022
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
Problem Substances : Anti-epidermal growth factor receptor monoclonal antibodies
[+]

The protective effects of thymol and carvacrol against di (2-ethylhexyl) phthalate-induced cytotoxicity in HEK-293 cells.May 05, 2022

Pubmed Data : J Biochem Mol Toxicol. 2022 May 6:e23092. Epub 2022 May 6. PMID: 35521929
Article Published Date : May 05, 2022
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Kidney Damage: Chemically-Induced, Phthalate Toxicity
Pharmacological Actions : Antioxidants, Renoprotective
Problem Substances : Phthalates
[+]

The results indicated a preventive effect of Z. multiflora extract and its constituent, carvacrol, on tracheal responsiveness and pathological changes of the lung.Apr 30, 2015

Pubmed Data : Phytother Res. 2015 May ;29(5):730-6. Epub 2015 Feb 13. PMID: 25682768
Article Published Date : Apr 30, 2015
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Zataria multiflora
Diseases : Chronic Obstructive Pulmonary Disease
Pharmacological Actions : Prophylactic Agents
Additional Keywords : Plant Extracts
Problem Substances : Dexamethasone
[+]

The results indicated that carvacrol protected from learning and memory impairment and the brain tissue inflammation and oxidative stress.Mar 31, 2020

Pubmed Data : Neurotox Res. 2020 Apr ;37(4):965-976. Epub 2019 Dec 6. PMID: 31811590
Article Published Date : Mar 31, 2020
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Brain: Oxidative Stress, Learning disorders, Lipopolysaccharide-Induced Toxicity, Memory Disorders
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

The results showed renoprotective effects of Zataria multiflora extract, carvacrol, and thymol in Cis-induced nephrotoxicity.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:8847212. Epub 2021 Jan 25. PMID: 33574884
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Thymol, Zataria multiflora
Diseases : Chemotherapy-Induced Kidney Damage, Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Chemoprotective Agents, Renoprotective
[+]

The use of Carvacrol as a promising new strategy for the prevention or treatment of Parkinson's disease may be considered.Jan 29, 2018

Pubmed Data : Brain Res Bull. 2018 Jan 30 ;139:9-15. Epub 2018 Jan 30. PMID: 29378222
Article Published Date : Jan 29, 2018
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

The Zataria multiflora extract had a potent bactericidal effect against A. baumannii that could downregulate the ompA gene.Jul 23, 2019

Pubmed Data : J Cell Biochem. 2019 Jul 24. Epub 2019 Jul 24. PMID: 31338900
Article Published Date : Jul 23, 2019
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Thymol, Zataria multiflora
Diseases : Acinetobacter baumannii infection
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Gene Expression
[+]

Therapeutic effect of carvacrol-loaded albumin nanoparticles on rheumatoid arthritis.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Pharm Res. 2020 ;19(1):312-320. PMID: 32922489
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Nitric Oxide Inhibitor
[+]

Therapeutic potential of Origanum vulgare leaf hydroethanolic extract against renal oxidative stress and nephrotoxicity induced by paraquat.Oct 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2019 Nov-Dec;9(6):563-573. PMID: 31763215
Article Published Date : Oct 31, 2019
Study Type : Animal Study
Additional Links
Substances : Oregano
Diseases : Kidney Damage: Chemically-Induced, Paraquat Toxicity, Pesticide Toxicity
Pharmacological Actions : Antioxidants, Renoprotective
Problem Substances : Paraquat
[+]

These results indicate that carvacrol is a potential alternative treatment for the excessive immune response induced by influenza virus A.Nov 01, 2020

Pubmed Data : J Ethnopharmacol. 2020 Nov 2:113555. Epub 2020 Nov 2. PMID: 33152425
Article Published Date : Nov 01, 2020
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Influenza A
Pharmacological Actions : Anti-Inflammatory Agents, Antiviral Agents, Immunomodulatory, Interferon Gamma Reducer, Interleukin-12 downregulation, Interleukin-2 Downregulation, Interleukin-4 downregulation, Interleukin-5 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Risk Reduction
[+]

This study demonstrates a distinct tumour-suppressive effect of oregano in a breast cancer model.Feb 22, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur J Nutr. 2016 Feb 23. Epub 2016 Feb 23. PMID: 26907089
Article Published Date : Feb 22, 2016
Study Type : Animal Study
Additional Links
Substances : Oregano
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-xL down-regulation
Additional Keywords : Cancer Stem Cells, Dose Response
[+]

Thyme and its constituents increase the activities of xenobiotic-metabolizing enzymes in mouse liver.Jan 01, 2005

Pubmed Data : J Med Food. 2005;8(2):184-9. PMID: 16117610
Article Published Date : Jan 01, 2005
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Thyme
Diseases : Xenobiotic Exposures
Pharmacological Actions : Phase I Detoxification Enzyme Inducer, Phase II Detoxification Enzyme Inducer
Additional Keywords : Plant Extracts
[+]

Thymol and carvacrol are highly promising candidates for the development of effective and safe drugs in the fight against visceral leishmaniasis.May 29, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 May 30 ;24(11). Epub 2019 May 30. PMID: 31151304
Article Published Date : May 29, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Leishmaniasis
Pharmacological Actions : Leishmanicidal
[+]

Zataria multiflora and carvacrol have a powerful hepatoprotective effects.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacopuncture. 2018 Dec ;21(4):249-257. Epub 2018 Dec 31. PMID: 30652051
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Zataria multiflora
Diseases : Acetaminophen (Tylenol) Toxicity , Liver Damage
Pharmacological Actions : Hepatoprotective
Problem Substances : Acetaminophen, Paracetamol
[+]

Zataria multiflora and its constituent, carvacrol, counteract sepsis-induced aortic and cardiac toxicity.May 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Animal Model Exp Med. 2023 Jun ;6(3):221-229. Epub 2023 Jun 5. PMID: 37272426
Article Published Date : May 31, 2023
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Zataria multiflora
Diseases : Lipopolysaccharide-Induced Toxicity, Oxidative Stress, Sepsis
Pharmacological Actions : Antioxidants, Cardioprotective, Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts
[+]

Carvacrol (oregano), geraniol (geranium) and thymol (thyme) have significant anti-Candida activity and contribute to dissolving biofim. Jun 01, 2008

Pubmed Data : Int J Antimicrob Agents. 2008 Jun;31(6):572-6. Epub 2008 Apr 28. PMID: 18440786
Article Published Date : Jun 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Geranium, Oregano, Thyme
Diseases : Candida Infection , Candidiasis, Fungal Infections: Biofilm Formation/Resistance
Pharmacological Actions : Antifungal Agents
Additional Keywords : Biofilm
[+]

Synergistic antimicrobial combination of carvacrol and thymol impairs single and mixed-species biofilms of Candida albicans and Staphylococcus epidermidis Jan 10, 2020

Pubmed Data : Biofouling. 2020 11 ;36(10):1256-1271. Epub 2021 Jan 12. PMID: 33435734
Article Published Date : Jan 10, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Candida Albicans, Staphylococcus epidermidis
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation, Natural Substance Synergy
[+]

The results of the present study show that the 3 plant-derived essential oils can be used to prepare tomato-based antimicrobial edible films that are effective against Listeria, E. coli, and Salmonella.Sep 01, 2009

Pubmed Data : J Food Sci. 2009 Sep ;74(7):M390-7. PMID: 19895486
Article Published Date : Sep 01, 2009
Study Type : Bacterial
Additional Links
Substances : Allspice, Garlic, Oregano
Diseases : Escherichia coli Infections, Foodborne Pathogens: Prevention/Food Preservation, Listeria Infections, Salmonella Infections
Pharmacological Actions : Anti-Bacterial Agents
[+]

A combination of plant extracts could induce antiproliferative and apoptosis in acute myeloid leukemia cells.May 06, 2016

Pubmed Data : Biomed Pharmacother. 2016 May 7 ;82:80-89. Epub 2016 May 7. PMID: 27470342
Article Published Date : May 06, 2016
Study Type : In Vitro Study
Additional Links
Substances : Oregano, Rose , Rose Hips, Sage, Sea buckthorn, Vitamin D
Diseases : Acute Myeloid Leukemia
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Natural Substance Synergy, Plant Extracts
[+]

A comprehensive review of herbal supplements used for persistent symptoms attributed to lyme disease.Feb 28, 2023

Pubmed Data : Integr Med (Encinitas). 2023 Mar ;22(1):30-38. PMID: 37101730
Article Published Date : Feb 28, 2023
Study Type : Review
Additional Links
Substances : Andrographis, Astragalus, Chinese Skullcap , Cordyceps sinensis, Garlic, Lemon Balm, Oregano, Peppermint, Reishi Mushroom, Thyme, Wormwood
Diseases : Lyme Disease
Pharmacological Actions : Antiparasitic Agents
[+]

A herbal antifungal formulation of Thymus serpillum, Origanum vulgare and Rosmarinus officinalis for treating ovine dermatophytosis due to Trichophyton mentagrophytes.Apr 30, 2013

Pubmed Data : Mycoses. 2013 May ;56(3):333-7. Epub 2013 Feb 1. PMID: 23368893
Article Published Date : Apr 30, 2013
Study Type : In Vitro Study
Additional Links
Substances : Oregano, Thyme
Diseases : Dermatophytoses
Pharmacological Actions : Antifungal Agents
Additional Keywords : Topical Treatment
[+]

A review of dietary plants for the prevention and management of kidney stones.Mar 06, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2018 Mar 7 ;19(3). Epub 2018 Mar 7. PMID: 29518971
Article Published Date : Mar 06, 2018
Study Type : Review
Additional Links
Substances : Green Tea, Hibiscus sabdariffa , Nettle, Nigella sativa (aka Black Seed), Oregano, Parsley, Pomegranate, Raspberry
Diseases : Kidney Stones
[+]

A review of the antimicrobial activity of basil, oregano, and thyme essential oils.Mar 27, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Microbiol Biotechnol. 2017 Mar 28 ;27(3):429-438. PMID: 27994215
Article Published Date : Mar 27, 2017
Study Type : Review
Additional Links
Substances : Basil, Oregano, Thyme
Pharmacological Actions : Antimicrobial
Additional Keywords : Essential Oils
[+]

A systematic appraisal of the use of carvacrol-rich plants to treat hydatid cysts.Aug 31, 2022

Pubmed Data : J Parasit Dis. 2022 Sep ;46(3):916-922. Epub 2022 Jan 16. PMID: 36091288
Article Published Date : Aug 31, 2022
Study Type : Review
Additional Links
Substances : Carvacrol
Diseases : Hydatid Cyst
Pharmacological Actions : Antiparasitic Agents
Additional Keywords : Essential Oils
[+]

Anti-biofilm activities of essential oils rich in carvacrol and thymol against Salmonella Enteritidis.Feb 28, 2019

Pubmed Data : Biofouling. 2019 Mar ;35(3):361-375. Epub 2019 May 14. PMID: 31088182
Article Published Date : Feb 28, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Salmonella Infections
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation, Essential Oils
[+]

Anti-biofilm inhibitory synergistic effects of combinations of essential oils and antibiotics.Sep 23, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antibiotics (Basel). 2020 Sep 24 ;9(10). Epub 2020 Sep 24. PMID: 32987638
Article Published Date : Sep 23, 2020
Study Type : In Vitro Study
Additional Links
Substances : Cinnamon, Oregano, Peppermint, Thyme
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation, Essential Oils, Natural Substance/Drug Synergy
[+]

Anti-cholinesterase and anti-α-amylase activities and neuroprotective effects of carvacrol.Mar 22, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2023 Mar 23 ;24(7). Epub 2023 Mar 23. PMID: 37047044
Article Published Date : Mar 22, 2023
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Hydrogen Peroxide Induced Toxicity
Pharmacological Actions : Alpha-amylase inhibitor, Cholinesterase Inhibitors, Neuroprotective Agents
[+]

Anti-inflammatory and antioxidant activity of carvacrol in the respiratory system.Apr 05, 2020

Pubmed Data : Phytother Res. 2020 Apr 6. Epub 2020 Apr 6. PMID: 32249518
Article Published Date : Apr 05, 2020
Study Type : Review
Additional Links
Substances : Carvacrol
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-4 downregulation, Interleukin-8 downregulation, Malondialdehyde Down-regulation
[+]

Anti-proliferative activity of Origanum vulgare inhibited lipogenesis and induced mitochondrial mediated apoptosis in human stomach cancer cell lines.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2018 Dec ;108:1835-1844. Epub 2018 Oct 19. PMID: 30372889
Article Published Date : Nov 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Gastric Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
[+]

Antibacterial and antibiofilm activity of carvacrol against oral pathogenic bacteria.Dec 12, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Metabolites. 2022 Dec 13 ;12(12). Epub 2022 Dec 13. PMID: 36557293
Article Published Date : Dec 12, 2022
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Steptococcus Mutans Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation
[+]

Antifungal activity of essential oils against azole-resistant and azole-susceptible vaginal Candida glabrata strains.Sep 30, 2018

Pubmed Data : Can J Microbiol. 2018 Oct ;64(10):647-663. Epub 2018 May 10. PMID: 29746162
Article Published Date : Sep 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Anise, Basil, Bay Laurel, Bergamot, Ginger, Grapefruit, Lavender, Mint, Oregano, Rosemary, Tea Tree
Diseases : Candida Glabrata, Candidiasis: Vulvovaginal
Pharmacological Actions : Antifungal Agents
Additional Keywords : Essential Oils
[+]

Antifungal activity of thymol and carvacrol against postharvest pathogens Botrytis cinerea.Apr 30, 2019

Pubmed Data : J Food Sci Technol. 2019 May ;56(5):2611-2620. Epub 2019 Apr 15. PMID: 31168143
Article Published Date : Apr 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Pharmacological Actions : Antifungal Agents
Additional Keywords : Plant Disease
[+]

Antihypertensive effect of carvacrol is improved after incorporation in β-cyclodextrin as a drug delivery system.Oct 31, 2020

Pubmed Data : Clin Exp Pharmacol Physiol. 2020 Nov ;47(11):1798-1807. Epub 2020 Aug 7. PMID: 32568422
Article Published Date : Oct 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Hypertension
Pharmacological Actions : Anti-Inflammatory Agents, Antihypertensive Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation
[+]

Antimicrobial and antioxidant activities and chemical characterization of essential oils of Thymusvulgaris, Rosmarinus officinalis, and Origanum majorana.Dec 31, 2014

Pubmed Data : Pak J Pharm Sci. 2015 Jan ;28(1 Suppl):363-9. PMID: 25631514
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Oregano, Rosemary, Thyme
Diseases : Fungal Infection, Oxidative Stress
Pharmacological Actions : Antimicrobial, Antioxidants
Additional Keywords : Essential Oils
[+]

Antioxidant efficacy of thymol and carvacrol in microencapsulated walnut oil triacylglycerols.Apr 24, 2019

Pubmed Data : Food Chem. 2019 Apr 25 ;278:805-810. Epub 2018 Dec 4. PMID: 30583446
Article Published Date : Apr 24, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol, Walnut
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Oils
[+]

Antiproliferative and anti-invasion effects of carvacrol on PC3 human prostate cancer cells.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Prev Med. 2019 ;10:156. Epub 2019 Oct 9. PMID: 32133074
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Prostate Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic, Antiproliferative , Interleukin-6 Downregulation, STAT3 Inhibitor
[+]

Antitumor effects of carvacrol and thymol: A systematic review. Dec 31, 2020

Pubmed Data : Front Pharmacol. 2021 ;12:702487. Epub 2021 Jul 7. PMID: 34305611
Article Published Date : Dec 31, 2020
Study Type : Review
Additional Links
Substances : Carvacrol, Thymol
Diseases : Cancers: All
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Antiviral mechanism of carvacrol on HSV-2 infectivity.Nov 10, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Infect Dis. 2020 Nov 11 ;20(1):832. Epub 2020 Nov 11. PMID: 33176697
Article Published Date : Nov 10, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Herpes Simplex Virus Type 2
Pharmacological Actions : Antiviral Agents
[+]

AXL protein is a crucial therapeutic target of carvacrol-induced inhibition of NSCLC cell proliferation and migration.Dec 31, 2017

Pubmed Data : Anticancer Res. 2018 01 ;38(1):279-286. PMID: 29277784
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer
Pharmacological Actions : Anti-metastatic, Antineoplastic Agents, Antiproliferative
[+]

Basil, clove, garlic, horseradish, marjoram, oregano, rosemary, and thyme exhibit antimicrobial activity against Vibrio parahaemolyticus.Aug 15, 2006

Pubmed Data : Int J Food Microbiol. 2006 Aug 15;111(1):6-11. Epub 2006 Jun 22. PMID: 16797760
Article Published Date : Aug 15, 2006
Study Type : In Vitro Study
Additional Links
Substances : Basil, Clove, Garlic, Horseradish, Marjoram, Oregano, Rosemary, Thyme
Diseases : Vibrio Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Plant Extracts
[+]

Beneficial Effects of Carvacrol on In Vitro Models of metabolically-associated liver steatosis and endothelial dysfunction.Mar 31, 2022

Pubmed Data : Curr Med Chem. 2022 Apr 1. Epub 2022 Apr 1. PMID: 35366761
Article Published Date : Mar 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Endothelial Dysfunction, Liver Steatosis
Pharmacological Actions : Hepatoprotective
[+]

Bioactive compounds of the O. vulgare ethanolic extract could yield novel products to fight dental caries.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Microbiol. 2022 ;13:999839. Epub 2022 Nov 2. PMID: 36406439
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Dental Caries
Pharmacological Actions : Anti-Bacterial Agents, Antimicrobial
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation
[+]

Carvacrol (found in oregano, savory, thymbra, thyme, corydothymus) is a potent inhibitor of cell growth in non-small cell carcinoma lines.Nov 01, 2003

Pubmed Data : Cytotechnology. 2003 Nov;43(1-3):149-54. PMID: 19003220
Article Published Date : Nov 01, 2003
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Oregano, Savory, Thyme
Diseases : Carcinoma: Non-Small-Cell Lung
Pharmacological Actions : Antiproliferative
[+]

Carvacrol affects breast cancer cells through TRPM7 mediated cell cycle regulation.Dec 09, 2020

Pubmed Data : Life Sci. 2020 Dec 10 ;266:118894. Epub 2020 Dec 10. PMID: 33310045
Article Published Date : Dec 09, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Carvacrol alleviates hyperuricemia-induced oxidative stress and inflammation.Dec 31, 2021

Pubmed Data : Drug Des Devel Ther. 2022 ;16:1159-1170. Epub 2022 Apr 22. PMID: 35496367
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Hyperuricemia, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor
[+]

Carvacrol and thymol inhibit biofilm formation of carbapenemase-producing gram negative bacilli strains.May 19, 2017

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2017 May 20 ;63(5):108-112. Epub 2017 May 20. PMID: 28719354
Article Published Date : May 19, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Gram-Negative Bacterial Infections
Pharmacological Actions : Antimicrobial
Additional Keywords : Biofilm
[+]

Carvacrol and thymol isolated from O. vulgare L. exhibit good bactericidal and antibiofilm activity against S. mutans.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : AMB Express. 2017 Dec ;7(1):49. Epub 2017 Feb 23. PMID: 28233286
Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Oregano, Thymol
Diseases : Dental Caries, Steptococcus Mutans Infections
Pharmacological Actions : Antimicrobial
Additional Keywords : Biofilm
[+]

Carvacrol arrests the proliferation of hypopharyngeal carcinoma cells.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2022 ;9:857256. Epub 2022 Apr 8. PMID: 35464036
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Nose & Throat Cancer
Pharmacological Actions : Antiproliferative
[+]

Carvacrol could be a novel and strong anticancer agent against the human gastric adenocarcinoma.Feb 26, 2017

Pubmed Data : Anticancer Drugs. 2017 Feb 27. Epub 2017 Feb 27. PMID: 28244942
Article Published Date : Feb 26, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Gastric Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Dose Response
[+]

Carvacrol could be a promising chemotherapeutic agent for prostate cancer.Sep 30, 2017

Pubmed Data : Nutr Cancer. 2017 Oct ;69(7):1075-1087. Epub 2017 Sep 5. PMID: 28872904
Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Prostate Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Carvacrol could be helpful to protect against neurodegeneration that occurs with aging and peripheral neurodegenerative diseases.Feb 29, 2020

Pubmed Data : Anat Sci Int. 2020 Mar ;95(2):230-239. Epub 2019 Dec 17. PMID: 31848974
Article Published Date : Feb 29, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

Carvacrol derivatives as antifungal agents.Sep 25, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Chim Slov. 2022 Sep 26 ;69(3):571-583. Epub 2022 Sep 26. PMID: 36196811
Article Published Date : Sep 25, 2022
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Candida Albicans
Pharmacological Actions : Anti-Bacterial Agents, Antifungal Agents
[+]

Carvacrol enhance apoptotic effect of 5-FU on MCF-7 cell line.Mar 31, 2022

Pubmed Data : Drug Res (Stuttg). 2022 Apr ;72(4):203-208. Epub 2022 Mar 4. PMID: 35253124
Article Published Date : Mar 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Breast Cancer, Cancers: Drug Resistant
Pharmacological Actions : Apoptotic
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil
[+]

Carvacrol enhances the antimicrobial potency of berberine in Bacillus subtilis.Mar 17, 2022

Pubmed Data : Curr Microbiol. 2022 Mar 18 ;79(5):135. Epub 2022 Mar 18. PMID: 35303184
Article Published Date : Mar 17, 2022
Study Type : In Vitro Study
Additional Links
Substances : Berberine, Carvacrol
Diseases : Bacillus subtilis infections
Pharmacological Actions : Antimicrobial
Additional Keywords : Natural Substance Synergy
[+]

Carvacrol exhibited rapid bactericidal action against S. pyogenes.Sep 20, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceutics. 2022 Sep 21 ;14(10). Epub 2022 Sep 21. PMID: 36297428
Article Published Date : Sep 20, 2022
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Streptococcus pyogenes
Pharmacological Actions : Anti-Bacterial Agents
[+]

Carvacrol exhibits chemopreventive potential against cervical cancer cells.Dec 29, 2020

Pubmed Data : Anticancer Agents Med Chem. 2020 Dec 30. Epub 2020 Dec 30. PMID: 33390139
Article Published Date : Dec 29, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Cervical Cancer
Pharmacological Actions : Antiproliferative , Chemopreventive
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil
[+]

Carvacrol exhibits modulatory effects on expression of pro-and anti-inflammatory cytokines.Feb 14, 2019

Pubmed Data : Life Sci. 2019 Feb 15 ;219:257-263. Epub 2018 Nov 23. PMID: 30472298
Article Published Date : Feb 14, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-6 Downregulation
[+]

Carvacrol exhibits rapid bactericidal activity against Streptococcus pyogenes through cell membrane damage.Jan 14, 2021

Pubmed Data : Sci Rep. 2021 Jan 15 ;11(1):1487. Epub 2021 Jan 15. PMID: 33452275
Article Published Date : Jan 14, 2021
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Streptococcus pyogenes
Pharmacological Actions : Anti-Bacterial Agents
[+]

Carvacrol induced Ca²⁺-dissociated cell death in PC3 human prostate cancer cells.Oct 30, 2017

Pubmed Data : Chin J Physiol. 2017 Oct 31 ;60(5):275-283. PMID: 28950692
Article Published Date : Oct 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Prostate Cancer
Pharmacological Actions : Chemotherapeutic
[+]

Carvacrol induced program cell death and cell cycle arrest in androgen-independent human prostate cancer cells.Jul 30, 2019

Pubmed Data : Anticancer Agents Med Chem. 2019 Jul 31. Epub 2019 Jul 31. PMID: 31364516
Article Published Date : Jul 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Prostate Cancer
Pharmacological Actions : Antiproliferative , Chemopreventive
Additional Keywords : Dose Response
[+]

Carvacrol induces mitochondria-mediated apoptosis via disruption of calcium homeostasis in human choriocarcinoma cells.Jan 31, 2019

Pubmed Data : J Cell Physiol. 2019 Feb ;234(2):1803-1815. Epub 2018 Aug 2. PMID: 30070691
Article Published Date : Jan 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Choriocarcinoma
Pharmacological Actions : Apoptotic
[+]

Carvacrol inhibits cadmium toxicity through combating against caspase dependent/independent apoptosis in PC12 cells.Sep 24, 2019

Pubmed Data : Food Chem Toxicol. 2019 Sep 25:110835. Epub 2019 Sep 25. PMID: 31562949
Article Published Date : Sep 24, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Cadmium Poisoning
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents, Nrf2 activation
Problem Substances : Cadmium
[+]

Carvacrol inhibits quorum sensing in opportunistic bacterium Aeromonas hydrophila.Aug 06, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Microorganisms. 2023 Aug 7 ;11(8). Epub 2023 Aug 7. PMID: 37630587
Article Published Date : Aug 06, 2023
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Aeromonas hydrophila
Pharmacological Actions : Anti-Bacterial Agents, Quorum Sensing Inhibition
[+]

Carvacrol loaded nanostructured lipid carriers as a promising parenteral formulation for leishmaniasis treatment.Apr 05, 2020

Pubmed Data : Eur J Pharm Sci. 2020 Apr 6:105335. Epub 2020 Apr 6. PMID: 32272211
Article Published Date : Apr 05, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Leishmaniasis
Pharmacological Actions : Leishmanicidal
[+]

Carvacrol may have potential therapeutic functions for the treatment of osteoarthritis.Feb 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2018 Mar ;17(3):3987-3992. Epub 2017 Dec 19. PMID: 29257341
Article Published Date : Feb 28, 2018
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Inflammation, Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Matrix metalloproteinase-3 (MMP-3) inhibitor, NF-kappaB Inhibitor
[+]

Carvacrol nanoemulsion evokes cell cycle arrest, apoptosis induction and autophagy inhibition in doxorubicin resistant-A549 cell line.Feb 05, 2018

Pubmed Data : Artif Cells Nanomed Biotechnol. 2018 Feb 6:1-12. Epub 2018 Feb 6. PMID: 29405784
Article Published Date : Feb 05, 2018
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Cancers: Drug Resistant, Carcinoma: Non-Small-Cell Lung
Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Inhibitors, Cell cycle arrest, Chemotherapeutic
[+]

Carvacrol possesses strong ameliorative effects on sepsis.Sep 30, 2017

Pubmed Data : Inflammation. 2017 Oct ;40(5):1654-1663. PMID: 28646428
Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Carvacrol prodrugs with antimicrobial activity loaded on clay nanocomposites.Apr 09, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Materials (Basel). 2020 Apr 10 ;13(7). Epub 2020 Apr 10. PMID: 32290211
Article Published Date : Apr 09, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Pharmacological Actions : Antimicrobial
[+]

Carvacrol promotes cell cycle arrest and apoptosis in MCF-7 breast cancer cells.Jun 21, 2020

Pubmed Data : Chin J Integr Med. 2020 Jun 22. Epub 2020 Jun 22. PMID: 32572774
Article Published Date : Jun 21, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bax/Bcl2 Ratio: Decrease, Cell cycle arrest
[+]

Carvacrol protects against diabetes-induced hypercontractility in the aorta through activation of the PI3K/Akt pathway.Apr 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2020 May ;125:109825. Epub 2020 Feb 7. PMID: 32036208
Article Published Date : Apr 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Diabetic Complications
Pharmacological Actions : Vasodilator Agents
[+]

Carvacrol protects mice against LPS-induced sepsis and attenuates inflammatory response in macrophages.Aug 06, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2023 Aug 7 ;13(1):12809. Epub 2023 Aug 7. PMID: 37550359
Article Published Date : Aug 06, 2023
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation
[+]

Carvacrol reduced tissue damage and bone loss caused by ligation-induced periodontitis.Dec 31, 2016

Pubmed Data : J Periodontol. 2017 07 ;88(7):e120-e128. Epub 2017 Apr 7. PMID: 28387609
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Periodontitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Carvacrol regimens exhibited significant antimicrobial activity against KPC-producing K. pneumoniae.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2021 ;16(2):e0246003. Epub 2021 Feb 22. PMID: 33617571
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Klebsiella Infections
Pharmacological Actions : Anti-Bacterial Agents
[+]

Carvacrol shows good anti-M. tuberculosis activity and synergism with rifampicin.Dec 31, 2017

Pubmed Data : Future Microbiol. 2018 06 1 ;13:877-888. Epub 2018 Jun 7. PMID: 29877104
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Mycobacterium Tuberculosis
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Natural Substance/Drug Synergy
[+]

Carvacrol suppresses inflammatory responses in rheumatoid arthritis fibroblast-like synoviocytes.Nov 27, 2018

Pubmed Data : J Cell Biochem. 2018 Nov 28. Epub 2018 Nov 28. PMID: 30485517
Article Published Date : Nov 27, 2018
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Carvacrol suppresses LPS-induced pro-inflammatory activation in RAW 264.7 macrophages through ERK1/2 and NF-kB pathway.Jul 25, 2019

Pubmed Data : Int Immunopharmacol. 2019 Jul 26 ;75:105743. Epub 2019 Jul 26. PMID: 31357087
Article Published Date : Jul 25, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Carvacrol treatment suppressed the growth of HPV-C33A cervical cancer cells.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Chem. 2022 ;10:1064191. Epub 2023 Jan 11. PMID: 36712982
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Cervical Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Carvacrol was demonstrated to both have low toxicity and be effective in alleviating systemic infections with C. albicans.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Infect Microbiol. 2020 ;10:192. Epub 2020 Apr 30. PMID: 32426298
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Candida Albicans
Pharmacological Actions : Anti-Bacterial Agents
[+]

Carvacrol, cinnamaldehyde, thymol, or oregano oil inhibit Clostridum prefringens in beef.Jul 01, 2006

Pubmed Data : J Food Prot. 2006 Jul;69(7):1546-51. PMID: 16865884
Article Published Date : Jul 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Cinnamaldehyde, Cinnamon, Oregano, Thyme, Thymol
Diseases : Clostridium Infections
Pharmacological Actions : Anti-Bacterial Agents
[+]

Carvacrol-A natural phenolic compound with antimicrobial properties.Apr 26, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antibiotics (Basel). 2023 Apr 27 ;12(5). Epub 2023 Apr 27. PMID: 37237727
Article Published Date : Apr 26, 2023
Study Type : Review
Additional Links
Substances : Carvacrol
Diseases : Candida Albicans, Candida Glabrata
Pharmacological Actions : Antimicrobial
[+]

Cinnamomum zeylanicum, Origanum vulgare, and Curcuma longa essential oils: chemical composition, antimicrobial and antileishmanial activity.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:2421695. Epub 2019 Jan 15. PMID: 30766611
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Cinnamon, Oregano, Turmeric
Diseases : Leishmaniasis
Pharmacological Actions : Antimicrobial, Leishmanicidal
Additional Keywords : Essential Oils
[+]

Cinnamon and Oregano, containing cinnamaldehyde and carvacrol, respectively, exhibit powerful antimicrobial activity against antibiotic-resistant strains of Campylobacter jejuni isolates.Jun 01, 2008

Pubmed Data : J Food Prot. 2008 Jun;71(6):1145-9. PMID: 18592739
Article Published Date : Jun 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Cinnamaldehyde, Cinnamon, Oregano
Diseases : Campylobacter Infections, Infection: Antibiotic Resistant
[+]

Combination of carvacrol and thymol has antimicrobial activity against Staphylococcus aureus and antioxidant activity.Apr 18, 2019

Pubmed Data : Foodborne Pathog Dis. 2019 Apr 19. Epub 2019 Apr 19. PMID: 31009261
Article Published Date : Apr 18, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Staphylococcus aureus infection
Pharmacological Actions : Antimicrobial
[+]

Combined effect of carvacrol, thymol and nisin against Staphylococcus aureus and Salmonella Enteritidis.Dec 31, 2020

Pubmed Data : An Acad Bras Cienc. 2021 ;93(suppl 4):e20210550. Epub 2021 Nov 1. PMID: 34730626
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Nisin, Thymol
Diseases : Salmonella Infections, Staphylococcus aureus infection
Pharmacological Actions : Antimicrobial
[+]

Composition and antiproliferative effect of essential oil of Origanum vulgare against tumor cell lines.Sep 30, 2014

Pubmed Data : J Med Food. 2014 Oct ;17(10):1129-33. Epub 2014 Sep 17. PMID: 25230257
Article Published Date : Sep 30, 2014
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Breast Cancer, Colon Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Essential Oils, Plant Extracts
[+]

Computational evaluation of major components from plant essential oils as potent inhibitors of SARS-CoV-2 spike protein.Dec 04, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Mol Struct. 2020 Dec 5 ;1221:128823. Epub 2020 Jul 4. PMID: 32834111
Article Published Date : Dec 04, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Cinnamaldehyde, Geraniol , Thymol
Diseases : Coronavirus Infection
Pharmacological Actions : Antiviral Agents
Additional Keywords : Essential Oils
[+]

Didymin ameliorates hepatic injury through inhibition of MAPK and NF-κB pathways.Dec 31, 2016

Pubmed Data : Int Immunopharmacol. 2017 Jan ;42:130-138. Epub 2016 Nov 29. PMID: 27912149
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Oregano
Diseases : Chemically-Induced Liver Damage, Lipid Peroxidation
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Dietary flavonoid carvacrol triggers the apoptosis of human breast cancer MCF-7 cells via the p53/Bax/Bcl-2 axis.Dec 09, 2022

Pubmed Data : Med Oncol. 2022 Dec 10 ;40(1):46. Epub 2022 Dec 10. PMID: 36495389
Article Published Date : Dec 09, 2022
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Tumor Suppressor Protein p53 Upregulation
[+]

Discovery of bioactive natural products for the treatment of acute respiratory infections.Jun 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Planta Med. 2018 Jul ;84(9-10):684-695. Epub 2018 Mar 19. PMID: 29554706
Article Published Date : Jun 30, 2018
Study Type : Review
Additional Links
Substances : Anise, Bael , Black Currant, Black Pepper, Blackberry, Carrot, Chrysanthemum Indicum, Cinnamon, Elderberry, Fennel, Frankincense, Garlic, Honeysuckle, Lemon Balm, Lotus , Marigold, Medicinal Mushrooms, Mugwort, Neem, Oregano, Reishi Mushroom, Rose , Rosemary, White Mulberry , Wormwood
Diseases : Coxsackievirus Infections, Influenza, Respiratory Infections, Rhinovirus Infection
Pharmacological Actions : Antiviral Agents
[+]

Effect of carvacrol and thymol on NorA efflux pump inhibition in multidrug-resistant (MDR) Staphylococcus aureus strains.Jun 21, 2021

Pubmed Data : J Bioenerg Biomembr. 2021 Jun 22. Epub 2021 Jun 22. PMID: 34159523
Article Published Date : Jun 21, 2021
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Infection: Antibiotic Resistant, Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents
[+]

Effect of carvacrol on the biological behavior of leukemia cells and its mechanism.Mar 31, 2022

Pubmed Data : Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2022 Apr ;30(2):393-399. PMID: 35395969
Article Published Date : Mar 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Leukemia
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Effects of carvacrol, thymol and essential oils containing such monoterpenes on wound healing: a systematic review.Jan 31, 2019

Pubmed Data : J Pharm Pharmacol. 2019 Feb ;71(2):141-155. Epub 2018 Dec 7. PMID: 30537169
Article Published Date : Jan 31, 2019
Study Type : Review
Additional Links
Substances : Carvacrol, Thymol
Diseases : Oxidative Stress, Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Essential Oils
[+]

Enhancement in site-specific delivery of carvacrol against methicillin resistant Staphylococcus aureus induced skin infections.Nov 12, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceutics. 2019 Nov 13 ;11(11). Epub 2019 Nov 13. PMID: 31766227
Article Published Date : Nov 12, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Staphylococcus aureus: Methicillin-resistant (MRSA)
Pharmacological Actions : Anti-Bacterial Agents
[+]

Essential oil from Origanum vulgare completely inhibits the growth of multidrug-resistant cystic fibrosis pathogens.May 31, 2016

Pubmed Data : Nat Prod Commun. 2016 Jun ;11(6):861-4. PMID: 27534136
Article Published Date : May 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Essential Oils: Unspecified, Oregano
Diseases : Cystic Fibrosis: Infections, Gram-Negative Bacterial Infections, Staphylococcus aureus infection
Pharmacological Actions : Antimicrobial
[+]

Essential oils from Origanum vulgare and Salvia officinalis exhibit antibacterial and anti-biofilm activities against Streptococcus pyogenes.Feb 12, 2018

Pubmed Data : Microb Pathog. 2018 Feb 13 ;117:118-127. Epub 2018 Feb 13. PMID: 29452197
Article Published Date : Feb 12, 2018
Study Type : In Vitro Study
Additional Links
Substances : Oregano, Sage
Diseases : Streptococcus Infections
Pharmacological Actions : Antimicrobial
Additional Keywords : Essential Oils
[+]

Evaluation of anti-enzyme properties of Origanum vulgare essential oil against oral Candida albicans.Feb 01, 2018

Pubmed Data : J Mycol Med. 2018 Feb 2. Epub 2018 Feb 2. PMID: 29402621
Article Published Date : Feb 01, 2018
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Candida Albicans
Pharmacological Actions : Antimicrobial, Enzyme Inhibitors
Additional Keywords : Essential Oils
[+]

Experimental treatment of cystic echinococcosis: combination therapy with carvacrol and thymol versus albendazole.Dec 31, 2022

Pubmed Data : Exp Parasitol. 2023 Jan ;244:108430. Epub 2022 Nov 23. PMID: 36435216
Article Published Date : Dec 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Echinococcosis
Pharmacological Actions : Antiparasitic Agents
[+]

Hydroalcoholic extract from Origanum vulgare induces a combined anti-mycobacterial and anti-inflammatory response in innate immune cells.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2019 ;14(3):e0213150. Epub 2019 Mar 4. PMID: 30830942
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Tuberculosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-12 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Hypoglycemic activity of Origanum vulgare L.Feb 24, 2021

Pubmed Data : Food Funct. 2021 Feb 25. Epub 2021 Feb 25. PMID: 33629672
Article Published Date : Feb 24, 2021
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Hypoglycemia
Pharmacological Actions : Hypoglycemic Agents
[+]

In vitro activities of carvacrol, cinnamaldehyde and thymol against Candida biofilms.Oct 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2021 Nov ;143:112218. Epub 2021 Sep 28. PMID: 34649348
Article Published Date : Oct 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Cinnamaldehyde, Thymol
Diseases : Candida Albicans, Candidiasis
Pharmacological Actions : Antifungal Agents
[+]

Inhibition of growth and virulence of Vibrio cholerae by carvacrol, an essential oil component of Origanum.Feb 04, 2021

Pubmed Data : J Appl Microbiol. 2021 Feb 5. Epub 2021 Feb 5. PMID: 33544959
Article Published Date : Feb 04, 2021
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Oregano
Diseases : Cholera
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Essential Oils
[+]

Natural antimicrobials extracted from oregano have an inhibitory activity against S. aureus strains from swine origin.Jul 21, 2019

Pubmed Data : J Appl Microbiol. 2019 Jul 22. Epub 2019 Jul 22. PMID: 31328837
Article Published Date : Jul 21, 2019
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Staphylococcus aureus infection
Pharmacological Actions : Antimicrobial
Additional Keywords : Essential Oils
[+]

Natural compounds rosmarinic acid and carvacrol counteract aluminium-induced oxidative stress.Apr 14, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Apr 15 ;25(8). Epub 2020 Apr 15. PMID: 32326410
Article Published Date : Apr 14, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Rosemaric Acid
Diseases : Aluminum Toxicity , Oxidative Stress
Pharmacological Actions : Antioxidants, Hepatoprotective, Neuroprotective Agents
[+]

Neuroprotective potential and underlying pharmacological mechanism of carvacrol for Alzheimer's and Parkinson's diseases.Dec 22, 2022

Pubmed Data : Curr Neuropharmacol. 2022 Dec 23. Epub 2022 Dec 23. PMID: 36567278
Article Published Date : Dec 22, 2022
Study Type : Review
Additional Links
Substances : Carvacrol
Diseases : Alzheimer's Disease, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

New anti-leukemic effect of carvacrol and thymol combination through synergistic induction of different cell death pathways. Jan 13, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2021 Jan 14 ;26(2). Epub 2021 Jan 14. PMID: 33466806
Article Published Date : Jan 13, 2021
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Acute Myeloid Leukemia
Pharmacological Actions : Apoptotic
Additional Keywords : Natural Substance Synergy
[+]

Nigella sativa essential oil and its bioactive compounds as resistance modifiers against Staphylococcus aureus.Jan 22, 2019

Pubmed Data : Phytother Res. 2019 Jan 23. Epub 2019 Jan 23. PMID: 30672036
Article Published Date : Jan 22, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Nigella sativa (aka Black Seed), Thymoquinone
Diseases : Staphylococcus aureus infection
Pharmacological Actions : Antimicrobial
[+]

Oregano (carvacrol) oil has exception inhibitory activity against Candida Albicans.Apr 01, 2005

Pubmed Data : Mycopathologia. 2005 Apr;159(3):339-45. PMID: 15883716
Article Published Date : Apr 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Candidiasis
Pharmacological Actions : Antifungal Agents
[+]

Oregano (carvacrol) oil inhibits Candida Albicans.Mar 01, 2011

Pubmed Data : Obes Surg. 2011 Mar;21(3):356-61. PMID: 12428445
Article Published Date : Mar 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Oregano
Diseases : Candidiasis
Pharmacological Actions : Antifungal Agents
[+]

Oregano and thyme extract prevents copper-induced oxidation of human low-density lipoproteins. Mar 01, 2007

Pubmed Data : Int J Food Sci Nutr. 2007 Mar;58(2):87-93. PMID: 17469764
Article Published Date : Mar 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Oregano, Thyme
Diseases : Cholesterol: Oxidation
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Oregano essential oil-pectin edible films as anti-quorum sensing and food antimicrobial agents.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Microbiol. 2014 ;5:699. Epub 2014 Dec 17. PMID: 25566215
Article Published Date : Dec 31, 2013
Study Type : Bacterial
Additional Links
Substances : Oregano
Pharmacological Actions : Anti-Bacterial Agents, Quorum Sensing Inhibition
[+]

Oregano extracts demonstrate significant activity against Mycobacterium avium. - Article 1Oct 01, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Appl Environ Microbiol. 2008 Oct;74(19):5986-90. PMID: 18676709
Article Published Date : Oct 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Oregano
Diseases : Mycobacterium Avium , Mycobacterium Infections
[+]

Oregano induces programmed cell death in human colon cancer cells.Jan 01, 2009

Pubmed Data : Nutr Cancer. 2009;61(3):381-9. PMID: 19373612
Article Published Date : Jan 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Colon Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Plant Extracts
[+]

Oregano kills Giardia intestinalis trophozoites in vitro.May 01, 2006

Pubmed Data : Parasitol Res. 2006 May;98(6):557-60. Epub 2006 Jan 20. PMID: 16425064
Article Published Date : May 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Giardiasis, Protozoan Infections
Pharmacological Actions : Antiprotozoal Agents
Additional Keywords : Plant Extracts
[+]

Oregano may prevent and ameliorate metabolic syndrome and its complications. Dec 24, 2008

Pubmed Data : J Agric Food Chem. 2008 Dec 24;56(24):11621-30. PMID: 19053389
Article Published Date : Dec 24, 2008
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Metabolic Syndrome X
Additional Keywords : Plant Extracts
[+]

Oregano oil and monolaurin may prove to be useful antimicrobial agents for prevention and therapy of Staphylococcus aureus infections.Apr 01, 2005

Pubmed Data : Mol Cell Biochem. 2005 Apr;272(1-2):29-34. PMID: 16010969
Article Published Date : Apr 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Monolaurin, Oregano
Diseases : Staphylococcal Infections, Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents
[+]

Oregano oil inhibits a wide range of pathogens, especially Candida Albicans.Feb 01, 2006

Pubmed Data : J Food Prot. 2006 Feb;69(2):369-75 PMID: 16496578
Article Published Date : Feb 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Candida Infection
Pharmacological Actions : Antifungal Agents
[+]

Oregano oil is a safe supplement to antiretrovirals, potentially delaying disease progression and resistance development.Jan 15, 2020

Pubmed Data : J Virol. 2020 07 16 ;94(15). Epub 2020 Jul 16. PMID: 32461309
Article Published Date : Jan 15, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Oregano
Diseases : HIV Infections
Pharmacological Actions : Antiviral Agents
[+]

Oregano powder reduces Streptococcus and increases SCFA concentration in a mixed bacterial culture assay.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2019 ;14(12):e0216853. Epub 2019 Dec 10. PMID: 31821320
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Streptococcus Infections
Pharmacological Actions : Anti-Bacterial Agents, Gastrointestinal Agents
[+]

Oregano: A potential prophylactic treatment for the intestinal microbiotaSep 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Heliyon. 2019 Oct ;5(10):e02625. Epub 2019 Oct 11. PMID: 31667426
Article Published Date : Sep 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Klebsiella Infections, Proteus Vulgaris Infections, Staphylococcal Infections
Pharmacological Actions : Gastrointestinal Agents, Prophylactic Agents
[+]

Origanum majorana showed apparent protective and curative effect on cadmium-induced hepatotoxicity and nephrotoxicity.Jul 31, 2011

Pubmed Data : Saudi Med J. 2011 Aug ;32(8):797-805. PMID: 21858388
Article Published Date : Jul 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced
Pharmacological Actions : Hepatoprotective, Renoprotective
Additional Keywords : Plant Extracts
Problem Substances : Cadmium
[+]

Origanum Syriacum essential oils have an antimicrobial activity.Aug 16, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Odontology. 2020 Aug 17. Epub 2020 Aug 17. PMID: 32808051
Article Published Date : Aug 16, 2020
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Denture Stomatitis
Pharmacological Actions : Antimicrobial
[+]

Origanum vulgare essential oil affects pathogens causing vaginal infections.Apr 30, 2017

Pubmed Data : J Appl Microbiol. 2017 May ;122(5):1177-1185. Epub 2017 Apr 4. PMID: 28176439
Article Published Date : Apr 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Candida Infection
Pharmacological Actions : Antimicrobial
Additional Keywords : Essential Oils
[+]

Origanum vulgare essential oil: antibacterial activities and synergistic effect with polymyxin B against multidrug-resistant Acinetobacter baumannii.Nov 30, 2020

Pubmed Data : Mol Biol Rep. 2020 Dec ;47(12):9615-9625. Epub 2020 Nov 15. PMID: 33190200
Article Published Date : Nov 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Acinetobacter baumannii infection
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Natural Substance/Drug Synergy
[+]

Origanum vulgare L. essential oil inhibits the growth of carbapenem-resistant gram-negative bacteria.Jun 26, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Rev Soc Bras Med Trop. 2019 Jun 27 ;52:e20180502. Epub 2019 Jun 27. PMID: 31271619
Article Published Date : Jun 26, 2019
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Acinetobacter baumannii infection, Infection: Antibiotic Resistant, Klebsiella Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Essential Oils
[+]

Phenolic compounds from Origanum vulgare and their antioxidant and antiviral activities.Dec 31, 2013

Pubmed Data : Food Chem. 2014 ;152:300-6. Epub 2013 Dec 1. PMID: 24444941
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Coxsackievirus Infections, Herpes Simplex Virus Type 1, Respiratory Syncytial Virus Infections
Pharmacological Actions : Antioxidants, Antiviral Agents
Additional Keywords : Plant Extracts
[+]

Potential anticancer effect of carvacrol codrugs on human glioblastoma cells.Oct 26, 2020

Pubmed Data : Curr Drug Deliv. 2020 Oct 27. Epub 2020 Oct 27. PMID: 33109049
Article Published Date : Oct 26, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Glioblastoma
Pharmacological Actions : Antiproliferative
[+]

Preparation and optimization of aloe ferox gel loaded with Finasteride-Oregano oil nanocubosomes for treatment of alopecia.Nov 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Deliv. 2022 Dec ;29(1):284-293. PMID: 35019794
Article Published Date : Nov 30, 2022
Study Type : In Vitro Study
Additional Links
Substances : Aloe Ferox, Oregano
Diseases : Alopecia
[+]

Radioprotective effects of plants from the Lamiaceae family. Oct 28, 2020

Pubmed Data : Anticancer Agents Med Chem. 2020 Oct 29. Epub 2020 Oct 29. PMID: 33121420
Article Published Date : Oct 28, 2020
Study Type : Review
Additional Links
Substances : Holy Basil, Oregano, Peppermint, Rosemary
Diseases : Radiotherapy
Pharmacological Actions : Radioprotective
[+]

Selective essential oils from spice or culinary herbs have high activity against stationary phase and biofilm Borrelia burgdorferi.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Med (Lausanne). 2017 ;4:169. Epub 2017 Oct 11. PMID: 29075628
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Cinnamon, Clove, Oregano
Diseases : Lyme Disease
Pharmacological Actions : Antimicrobial
Additional Keywords : Biofilm, Essential Oils
[+]

Studies with fresh meat, meat products, fish, milk, dairy products and cooked rice have shown that the concentration of essential oils needed to achieve a significant antibacterial effect is around 0.5 microl g (-1) in foods and about .1 - 10 microl ml (-Aug 01, 2004

Pubmed Data : Int J Food Microbiol. 2004 Aug 1 ;94(3):223-53. PMID: 15246235
Article Published Date : Aug 01, 2004
Study Type : Bacterial
Additional Links
Substances : Carvacrol, Cinnamaldehyde, Cinnamic acid, Eugenol, Perillaldehyde, Thymol
Diseases : Foodborne Pathogens: Prevention/Food Preservation
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Food Preservation With Essential Oils
[+]

Tea Tree, Oregano, and Pelargonium sidoides exhibit synergistic anti-Candida activity with the drug amphotericin B. Aug 01, 2008

Pubmed Data : Phytomedicine. 2008 Aug;15(8):635-8. Epub 2008 Jun 24. PMID: 18579358
Article Published Date : Aug 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Oregano, Pelargonium sidoides, Tea Tree
Diseases : Candida Infection
Additional Keywords : Drug: Amphotericin B, Drug-Plant-Vitamin Synergies
[+]

The antibacterial mechanism of carvacrol and thymol against Escherichia coli.Aug 31, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lett Appl Microbiol. 2008 Sep ;47(3):174-9. PMID: 19552781
Article Published Date : Aug 31, 2008
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Escherichia coli Infections
Pharmacological Actions : Anti-Bacterial Agents
[+]

The combination of Cinnamaldehyde, Carvacrol, and honey showed a higher antibacterial effect than Imipenem.Feb 29, 2020

Pubmed Data : Microb Pathog. 2020 Mar ;140:103946. Epub 2019 Dec 23. PMID: 31874231
Article Published Date : Feb 29, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Cinnamaldehyde, Honey
Diseases : Infection: Antibiotic Resistant, Pseudomonas aeruginosa
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

The current research verified that oregano and its main constituents could be potentially utilized as anticancer therapeutic agents.Aug 29, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2017 Aug 30 ;22(9). Epub 2017 Aug 30. PMID: 28867805
Article Published Date : Aug 29, 2017
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Liver Cancer
Pharmacological Actions : Chemotherapeutic, Cytotoxic
[+]

The essential oil of oregano is effective in working synergistically with Nystatin in inhibiting Candida species.Oct 01, 2009

Pubmed Data : Phytomedicine. 2009 Oct;16(10):972-5. Epub 2009 Jul 18. PMID: 19616925
Article Published Date : Oct 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Oregano
Diseases : Candida Infection
Pharmacological Actions : Antifungal Agents
Additional Keywords : Drug: Nystatin, Drug-Plant-Vitamin Synergies
[+]

The flavonoid didymin, isolated from Origanum vulgare induces apoptosis in HepG2 cells through mitochondrial dysfunction.Nov 26, 2016

Pubmed Data : Chem Biol Interact. 2016 Nov 27 ;261:118-126. Epub 2016 Nov 27. PMID: 27899290
Article Published Date : Nov 26, 2016
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Oregano
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

The impact of some natural phenolic compounds on carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase, and α-glycosidase enzymes.Nov 30, 2017

Pubmed Data : J Biochem Mol Toxicol. 2017 Dec ;31(12). Epub 2017 Sep 13. PMID: 28902458
Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Chrysin, Citrus naringin, Ginger, Hesperidin, Polyphenols
Diseases : Hypoglycemia
Pharmacological Actions : Acetylcholinesterase Inhibitor, Alpha-glucosidase inhibitor , Hypoglycemic Agents
[+]

The vapors from Oregano, Perilla, Tea Tree, Lavender, Clove, and Geranium essential oils have antifungal activity against Trichophyton mentagrophytes. Dec 01, 2006

Pubmed Data : J Infect Chemother. 2006 Dec;12(6):349-54. Epub 2007 Jan 18. PMID: 17235639
Article Published Date : Dec 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Clove, Geranium, Lavender, Oregano, Perilla , Tea Tree
Diseases : Fungal Infection, Trichophytosis
Pharmacological Actions : Antifungal Agents
[+]

The volatile oils exhibited considerable inhibitory effects against all the organisms under test.Jan 31, 2000

Pubmed Data : J Appl Microbiol. 2000 Feb ;88(2):308-16. PMID: 10736000
Article Published Date : Jan 31, 2000
Study Type : Bacterial
Additional Links
Substances : Black Pepper, Clove, Geranium, Nutmeg, Oregano, Thyme
Diseases : Bacterial Infections and Mycoses, Foodborne Pathogens: Prevention/Food Preservation
Pharmacological Actions : Anti-Bacterial Agents
[+]

These results indicate that carvacrol's activity in inhibition of biofilm formation may be related to the disruption of quorum sensing.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(4):e93414. Epub 2014 Apr 1. PMID: 24691035
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Salmonella Infections, Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents, Quorum Sensing Inhibition
Additional Keywords : Biofilm
[+]

This paper reviews classical methods for evaluating antibacterial and antifungal activity of essential oils and gives an overview on the susceptibility of human and food-borne bacteria and fungi towards different essential oils and their constituents.May 01, 2003

Pubmed Data : Curr Med Chem. 2003 May ;10(10):813-29. PMID: 12678685
Article Published Date : May 01, 2003
Study Type : Review
Additional Links
Substances : Cinnamon, Mint, Oregano, Sage, Thyme
Diseases : Foodborne Pathogens: Prevention/Food Preservation
Pharmacological Actions : Anti-Bacterial Agents, Antifungal Agents
[+]

This preliminary evaluation demonstrated a synergistic property of O. vulgare and H. perforatum extracts in treating S. aureus infection.Feb 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Future Sci OA. 2019 Mar ;5(3):FSO371. Epub 2019 Jan 31. PMID: 30906567
Article Published Date : Feb 28, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Oregano, St. Johns Wort
Diseases : Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Natural Substance Synergy
[+]

This study led to the identification of carvacrol with strong binding affinity on mTOR receptor.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2020 ;2020:8830665. Epub 2020 Oct 26. PMID: 33163084
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Breast Cancer
Pharmacological Actions : Chemopreventive
[+]

This study provided the evidence regarding the protective effects of carvacrol and thymol against Aβ25–35-induced cytotoxicity in PC12 cells.Dec 31, 2019

Pubmed Data : Iran Biomed J. 2020 07 ;24(4):243-50. Epub 2020 Jan 22. PMID: 32306722
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

This work confirms the antimicrobial activity of specific Oregano and Thyme varieties, and suggests the use in treatment and prevention of salmonella.Dec 31, 2004

Pubmed Data : APMIS. 2005 Jan ;113(1):1-6. PMID: 15676008
Article Published Date : Dec 31, 2004
Study Type : In Vitro Study
Additional Links
Substances : Oregano, Thyme
Diseases : Salmonella Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Oregano, Thyme
[+]

Thymol and carvacrol downregulate the expression of Salmonella typhimurium virulence genes.Jun 06, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Microorganisms. 2020 Jun 7 ;8(6). Epub 2020 Jun 7. PMID: 32517327
Article Published Date : Jun 06, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Salmonella Infections
Pharmacological Actions : Anti-Bacterial Agents
[+]

Thymol and carvacrol protected against acetaminophen induced toxicity.Jan 21, 2016

Pubmed Data : Hum Exp Toxicol. 2016 Jan 22. Epub 2016 Jan 22. PMID: 26801986
Article Published Date : Jan 21, 2016
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Acetaminophen (Tylenol) Toxicity
Pharmacological Actions : Antioxidants, Hepatoprotective
Additional Keywords : Dose Response
Problem Substances : Acetaminophen, Paracetamol
[+]

Thymol seems to be a promising candidate for topical therapeutic application as antiviral agent for treatment of herpetic infections.Aug 29, 2017

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2017 Aug 30 ;63(8):42-47. Epub 2017 Aug 30. PMID: 28886313
Article Published Date : Aug 29, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Herpes Simplex Virus Type 1
Pharmacological Actions : Antiviral Agents
Additional Keywords : Essential Oils
[+]

Thymus vulgaris, a natural pharmacy against COVID-19: A molecular review.Feb 28, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Herb Med. 2023 Mar ;38:100635. Epub 2023 Jan 26. PMID: 36718131
Article Published Date : Feb 28, 2023
Study Type : Review
Additional Links
Substances : Carvacrol, Thyme, Thymol
Diseases : Coronavirus Infection
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Transforming growth factor beta (TGF-β) upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ursolic acid and carvacrol may be potential inhibitors of dormancy protein small heat shock protein16.3 of Mycobacterium tuberculosis.Sep 30, 2018

Pubmed Data : J Biomol Struct Dyn. 2018 Oct ;36(13):3434-3443. Epub 2017 Oct 20. PMID: 28984500
Article Published Date : Sep 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Ursolic Acid
Diseases : Mycobacterium Tuberculosis
Pharmacological Actions : Heat Shock Protein Down-Regulation
[+]

Virulence of Pseudomonas aeruginosa exposed to carvacrol: alterations of the Quorum sensing at enzymatic and gene levels.Mar 21, 2019

Pubmed Data : J Cell Commun Signal. 2019 Mar 22. Epub 2019 Mar 22. PMID: 30903602
Article Published Date : Mar 21, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol
Diseases : Pseudomonas aeruginosa
Pharmacological Actions : Quorum Sensing Inhibition
[+]

Would carvacrol be a supporting treatment option effective in minimizing the deleterious effects of COVID-19?Oct 19, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2021 Oct 20. Epub 2021 Oct 20. PMID: 34669001
Article Published Date : Oct 19, 2021
Study Type : Review
Additional Links
Substances : Carvacrol
Diseases : Coronavirus Infection
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta upregulation, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor

Copyright: dionisvera / 123RF Stock Photo

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