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Organosulfur Compounds
Views 1406
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300 Diseases Researched for Organosulfur Compounds
Name
AC
CK
Focus
Oxidative Stress
42
98
Inflammation
20
53
Athletic Performance: Recovery
4
40
Prostate Cancer
24
39
Breast Cancer
29
38
Colon Cancer
16
30
DNA damage
10
30
Helicobacter Pylori Infection
7
28
Breast Cancer: Triple Negative
7
27
Osteoarthritis
4
27
Cancers: All
15
24
Pancreatic Cancer
15
24
Autism Spectrum Disorders
3
21
Allergic Rhinitis
2
20
Schizophrenia
2
20
Bladder Cancer
8
19
Diabetes Mellitus: Type 2
7
18
Melanoma
6
17
Alzheimer's Disease
8
16
Depression
4
16
Insulin Resistance
4
16
Liver Cancer
13
16
Immune Disorders: Low Immune Function
4
15
Chemotherapy-Induced Toxicity: Cisplatin
8
14
Endothelial Dysfunction
6
14
Fatty Liver
3
14
Lipopolysaccharide-Induced Toxicity
11
14
Lung Cancer
10
14
Prostate Cancer: Prevention
4
14
Autism
2
12
Cancer Metastasis
10
12
Diesel Exhaust Particle Toxicity
3
12
Glutathione Deficiency
3
12
Muscle Damage: Exercise-Induced
2
12
Air Pollution Linked Toxicity
2
11
Skin Diseases
2
11
Anemia: Sickle Cell
1
10
Asthma
1
10
Athletic Performance
1
10
Bipolar Disorder
1
10
Bladder Degeneration
1
10
COPD
1
10
Cancers: Drug Resistant
5
10
Cognitive Decline/Dysfunction
5
10
Cystic Fibrosis
1
10
Cystitis
1
10
Gastritis
1
10
Hyperhomocysteinemia
1
10
Hyperinsulinism
1
10
Influenza in Swine
1
10
Interstitial Lung Diseases
1
10
Lung Diseases
1
10
Lymphopenia
1
10
Neutrophils: Elevated
1
10
Obesity
5
10
Osteoarthritis: Knee
1
10
Prostate: PSA Doubling
1
10
Pulmonary Fibrosis
1
10
Radical Prostatectomy
1
10
Respiratory Diseases
1
10
Rosacea
1
10
Swine Flu Associated Virus
1
10
Thrush
1
10
Cerebral Ischemia
5
9
Gastric Cancer
8
9
Colorectal Cancer
5
8
Chemically-Induced Liver Damage
5
7
Chemotherapy-Induced Toxicity: Doxorubicin
5
7
Hypoxia
5
7
Myocardial Ischemia
4
7
Neurodegenerative Diseases
5
7
Acetaminophen (Tylenol) Toxicity
3
6
Adenomatous Polyposis Coli
3
6
Hypertension
3
6
Spinal Cord Injuries
3
6
Testicular Injury: Chemical/Metal Induced
3
6
Cancer Stem Cells
5
5
Diabetic Nephropathy
3
5
Drug-Induced Toxicity: Indomethacin
3
5
Endothelial Damage
1
5
Gastric Ulcer
3
5
Glioblastoma
4
5
Ovarian Cancer
5
5
Pesticide Toxicity
3
5
Aflatoxicosis
3
4
Arteriosclerosis
2
4
Aspirin-Induced Toxicity
2
4
Brain Inflammation
3
4
Brain Injury: Traumatic
2
4
Brain: Microglial Activation
2
4
Cadmium Poisoning
3
4
Cardiovascular Diseases
4
4
Cervical Cancer
4
4
Chronic Kidney Disease (CKD)
2
4
Diabetic Complications
2
4
Head and Neck Cancer
4
4
Hydrogen Peroxide Induced Toxicity
4
4
Intestinal Polyps
2
4
Ischemia
2
4
Lead Poisoning
2
4
Leishmaniasis
2
4
Leukemia
4
4
Liver Disease
2
4
Lung Injury: Acute
2
4
Myocardial Infarction
2
4
NSAID-induced toxicity
2
4
Oral Cancer
3
4
Organ Transplantation: Pancreatic Islet Cells
2
4
Parkinson's Disease
4
4
Sepsis
2
4
Skin Cancer
3
4
Skin Cancer: Prevention
2
4
Traumatic Brain Injury
2
4
Advanced Glycation End products (AGE)
2
3
Aging Skin
2
3
Arsenic Poisoning
2
3
Benzo[a]pyrene-induced Toxicity
2
3
Blood-Brain-Barrier Disorders
2
3
Brain Cancer
3
3
Brain Damage
2
3
Carcinoma: Non-Small-Cell Lung
2
3
Cardiac Hypertrophy
2
3
Chemotherapy-Induced Toxicity
2
3
Colon Cancer: Prevention
2
3
Diabetes Mellitus: Type 1: Prevention
2
3
Glioma
3
3
Intestinal Diseases
2
3
Lipid Peroxidation
2
3
Liver Cancer: Prevention
2
3
Liver Damage: Aflatoxin-Induced
2
3
Low Disorders: Low TH1
2
3
Lymphoma
2
3
Melanoma: Metastatic
2
3
Multiple Myeloma
2
3
Nasopharyngeal Cancer
2
3
Neurologic Disorders
2
3
Osteosarcoma
2
3
Petroleum Exposure And Toxicity
2
3
Polycyclic aromatic hydrocarbon (PAH) toxicity
2
3
Promyelocytic leukemia
3
3
Rheumatoid Arthritis
2
3
Skin Diseases: Photo-Aging
2
3
Aging
2
2
Alcohol Toxicity
1
2
Alcoholic Liver Disease
1
2
Amebiasis
1
2
Amphetamine Addiction/Withdrawal
1
2
Antibiotic Toxicity
1
2
Anxiety Disorders
1
2
Arterial Calcification
1
2
Arterial Plaque
1
2
Arterial Thickening
1
2
Asphyxia
1
2
Atherosclerosis
1
2
Bacterial Infections and Mycoses
2
2
Bladder Dysfunction
1
2
Bladder Outlet Obstruction
1
2
Brain Edema
1
2
Brain Hypoxia
2
2
Breast Cancer: Metastatic
2
2
Cancers: Multi-Drug Resistant
1
2
Candida Infection
2
2
Carbon Monoxide Poisoning
1
2
Chemical Exposure
1
2
Chemical Weapon Agent Injury
1
2
Cholangiocarcinoma
1
2
Colitis
1
2
Depressive Disorder
1
2
Diabetes Mellitus: Type 1
1
2
Diabetes: Cognitive Dysfunction
1
2
Diabetes: Memory Problems
1
2
Drug-Induced Toxicity: Cyclosporine
1
2
Duchenne's Muscular Dystrophy
1
2
Epstein-Barr Virus Infections
1
2
Eye Damage
1
2
Fluoride Toxicity
1
2
Gastrointestinal Cancer
1
2
Gout
1
2
Hearing Loss
1
2
Heart Failure
1
2
Hypertension: Pulmonary
1
2
Hypoglycemia
2
2
Immune Dysregulation: TH1/TH2 imbalance
1
2
Intima Media Thickening
1
2
Intoxication
1
2
Kidney Damage: Chemically-Induced
1
2
Kidney Diseases
1
2
Kidney Stones
1
2
Light Sensitivity
1
2
Liver Damage
1
2
Low Immune Function: Natural Killer Cells
1
2
Malathion Toxicity
1
2
Mercury Poisoning
1
2
Muscle Fatigue
1
2
Muscle Soreness
1
2
Mycobacterium tuberculosis
1
2
Nephropathy
1
2
Neuropathic Pain
1
2
Nicotine/Tobacco Toxicity
1
2
Nonalcoholic fatty liver disease (NAFLD)
1
2
Obsessive-Compulsive Disorder
1
2
Organ Transplantation
1
2
Pancreatitis
1
2
Respiratory Syncytial Virus Infections
1
2
Respiratory Tract Infections
1
2
Right Ventricular Hypertrophy
1
2
Salivary Gland Adenoid Cystic Carcinoma.
2
2
Salivary Gland Diseases
2
2
Schistosomiasis
1
2
Schwannoma: Vestibular
1
2
Seizures
1
2
Serotonin Disorders
1
2
Smoking
1
2
Streptococcus infections: Group A
2
2
Stroke
1
2
Stroke: Recovery
1
2
Subarachnoid hemorrhage
1
2
Tumors
2
2
Uremia
1
2
Acute Myeloid Leukemia
1
1
Allergies
1
1
Androgen-Induced Diseases
1
1
Aortic Plaques
1
1
Aphthous Ulcer
1
1
Aspergillosis
1
1
Bone Destructive Diseases: Over-Active Osteoclasts
1
1
Brain Injury: Hippocampal Damage
1
1
Brain: Oxidative Stress
1
1
Breast Cancer: HER-2 Overexpressed
1
1
Breast Cancer: Prevention
1
1
Candidiasis
1
1
Canker Sore
1
1
Cardiovascular Disease: Prevention
1
1
Cholesterol: LDL/HDL ratio
1
1
Chronic Myeloid Leukemia
1
1
Colorectal Tumors
1
1
Dementia
1
1
Dental Caries
1
1
Dopamine Deficiency
1
1
Drug-Induced Toxicity
1
1
Dystrophic retinal detachment (DRD)
1
1
Encephalomyelitis
1
1
Endometrial Cancer
1
1
Excitotoxicity
1
1
Fibrosarcoma
1
1
Fibrosis
1
1
Fungal Infection
1
1
Gastrointestinal Diseases
1
1
Gastrointestinal Inflammation
1
1
Giardiasis
1
1
Gonorrhea
1
1
Gram-Negative Bacterial Infections
1
1
Gram-Positive Bacterial Infections
1
1
HDL: Low
1
1
HIV Infections
1
1
Hepatitis
1
1
Hepatitis C
1
1
Hepatitis: Lectin-Induced (concanavalin)
1
1
Heterocyclic Aromatic Amine Induced Toxicity
1
1
Hyperglycemia
1
1
Hyperlipidemia
1
1
IgE-Mediated Hypersensitivity
1
1
Infection: Antibiotic Resistant
1
1
Keloid
1
1
Kidney Damage
1
1
Leukemia: Acute promyelocytic leukemia
1
1
Leukemia: Chronic Lymphocytic Leukemia (CLL)
1
1
Low Human Growth Hormone
1
1
Lung Cancer: Prevention
1
1
Lymphoma: B-Cell
1
1
Lymphoma: Mantle Cell
1
1
MRSA
1
1
Macular Degeneration
1
1
Medulloblastoma
1
1
Melanism
1
1
Methicillin-resistant Staphylococcus aureus
1
1
Microcystis aeruginosa
1
1
Mitochondrial Diseases
1
1
Multiple Sclerosis
1
1
Napthalene-Induced Toxicity
1
1
Oral Cancer: Prevention
1
1
Osteoporosis: Over-active Osteoclasts
1
1
Pancreatic Cancer Stem Cell
1
1
Periodontal Diseases
1
1
Pneumococcal Infections
1
1
Prediabetes
1
1
Pseudomonas Infections
1
1
Restenosis
1
1
Retinal Diseases
1
1
Squamous cell carcinoma
1
1
Staphylococcus aureus infection
1
1
Staphylococcus aureus: Methicillin-resistant (MRSA)
1
1
Staphylococcus epidermidis
1
1
Stomach Cancer
1
1
Streptococcus Infections
1
1
Streptococcus infections: Group B
1
1
Striatonigral Degeneration: Autosomal Dominant
1
1
Sunburn
1
1
Thyroid Cancer
1
1
Ultraviolet Radiation Induced Damage
1
1
111 Pharmacological Actions Researched for Organosulfur Compounds
Name
AC
CK
Focus
Antioxidants
91
219
Anti-Inflammatory Agents
65
167
Apoptotic
101
144
Anticarcinogenic Agents
76
128
Chemopreventive
55
106
Antiproliferative
63
100
Neuroprotective Agents
40
77
Nrf2 activation
39
77
Tumor Necrosis Factor (TNF) Alpha Inhibitor
25
41
Phase II Detoxification Enzyme Inducer
14
40
Cell cycle arrest
30
34
Cardioprotective
16
33
Interleukin-1 beta downregulation
20
33
Cytoprotective
7
28
Hepatoprotective
12
28
NF-kappaB Inhibitor
22
27
Anti-metastatic
21
26
Cyclooxygenase 2 Inhibitors
14
26
Interleukin-6 Downregulation
17
26
Chemotherapeutic
18
25
Glutathione Upregulation
5
24
Antineoplastic Agents
17
22
Anti-Allergic Agents
2
20
Histone deacetylase inhibitor
10
19
Enzyme Inhibitors
8
17
Antidepressive Agents
4
16
Chemosensitizer
13
16
Renoprotective
9
16
Anti-Apoptotic
9
15
Genoprotective
3
13
Matrix metalloproteinase-9 (MMP-9) inhibitor
9
13
Superoxide Dismutase Up-regulation
5
13
Chemoprotective Agents
7
12
Matrix metalloproteinase-2 (MMP-2) inhibitor
7
12
MicroRNA modulator
11
11
Anti-Bacterial Agents
10
10
Anticholesteremic Agents
1
10
Insulin Down-Regulation
1
10
Malondialdehyde Down-regulation
5
9
NF-E2-Related Factor-2 (Nrf2) Modulator
8
9
Heme oxygenase-1 up-regulation
6
7
Immunomodulatory
5
7
Antihypertensive Agents
3
6
Autophagy Up-regulation
4
6
Hypolipidemic
4
6
Anti-Angiogenic
4
5
Antifungal Agents
4
4
Antiviral Agents
3
4
Bcl-2 protein down-regulation
4
4
Gastroprotective
2
4
Heat Shock Protein Inducer
2
4
Leishmanicidal
2
4
Telomerase Inhibitor
4
4
Vascular Endothelial Growth Factor Inhibitors
2
4
Anti-Proliferative
2
3
Anti-Ulcer Agents
2
3
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
2
3
Radioprotective
2
3
Tumor Suppressor Protein p53 Upregulation
3
3
Angiogenesis Inhibitors
1
2
Anti-Anxiety Agents
1
2
Anti-Fibrotic
2
2
Anticonvulsants
1
2
Antimicrobial
2
2
Antinoceceptive
1
2
Autophagy Inhibitors
1
2
Detoxifier
2
2
Epidermal growth factor receptor (EGFR) inhibitor
1
2
Hypotensive
1
2
Immunomodulatory: Th17 downregulation
1
2
Interleukin-17 downregulation
1
2
Interleukin-18 down-regulation
1
2
Interleukin-2 upregulation
1
2
Interleukin-8 downregulation
2
2
Leptin Down-Regulation
1
2
P21 Activation
2
2
Phase I Detoxification Enzyme Inducer
1
2
Photoprotective
1
2
Prostaglandin PGE2 downregulation
1
2
Proteasome Inhibitors
2
2
STAT3 Activation
1
2
Schistosomicides
1
2
Serotonergic
1
2
Vasodilator Agents
1
2
Wnt/β-catenin signaling pathway modulation
2
2
Anti Inflammatory
1
1
Anti-Glycation Agents
1
1
Anti-atherogenic
1
1
Antimitotic Agents
1
1
Antiparasitic Agents
1
1
Beta-Defensin-2 Up-Regulation
1
1
Caspase-3 Activation
1
1
Cell Differentiation Inducer
1
1
Cytotoxic
1
1
Estrogen Receptor Modulators
1
1
HMG-CoA reductase inhibitor
1
1
Hypoglycemic Agents
1
1
Immunostimulatory
1
1
Interferon Gamma Reducer
1
1
Interleukin-1 alpha downregulation
1
1
Interleukin-10 upregulation
1
1
Interleukin-4 upregulation
1
1
Postaglandin PGE2 downregulation
1
1
Quinone Reductase-Inducer
1
1
Radiopharmaceuticals
1
1
Radiosensitizer
1
1
Secretagogue
1
1
Survivin Down-Regulation
1
1
Vascular Cell Adhesion Molecule-1 Inhibitor
1
1
Vascular Endothelial Growth Factor Regulator
1
1
Wnt/β-catenin pathway down-regulation
1
1
Research Articles
481
Cumulative Knowledge Score
778
Overall Research Rating
EXCELLENT
Related Topics
The Following are Sub-Topics of Organosulfur Compounds
Allicin
Sulforaphane
MSM (Methylsulfonylmethane)
Cysteine (see N-Acetylcysteine)
Cysteine (see N-Acetylcysteine)
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938 Abstracts with Organosulfur Compounds Research
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[+]
Sulforaphane ameliorates lipid profile.
Apr 07, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2021 Apr 8 ;11(1):7804. Epub 2021 Apr 8. PMID:
33833347
Article Published Date
: Apr 07, 2021
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Sulforaphane
Diseases
:
Cardiovascular Diseases
,
Hypertension
,
Nonalcoholic fatty liver disease (NAFLD)
,
Obesity
Pharmacological Actions
:
Hypolipidemic
[+]
Sulforaphane exhibits potent renoprotective effects in preclinical models of kidney diseases.
May 31, 2023
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2023 Jun 1 ;322:121664. Epub 2023 Apr 5. PMID:
37023957
Article Published Date
: May 31, 2023
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Sulforaphane
Diseases
:
Kidney Diseases
Pharmacological Actions
:
Renoprotective
[+]
Allicin as an add-on therapy improves H. pylori eradication, healing of ulcers, and remission of symptoms.
Oct 20, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Gastroenterol. 2019 Oct 21 ;25(39):6025-6040. PMID:
31660038
Article Published Date
: Oct 20, 2019
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Allicin
Diseases
:
Helicobacter Pylori Infection
Pharmacological Actions
:
Gastrointestinal Agents
,
Gastroprotective
[+]
Sulforaphane and EGCG restore estrogen receptor expression by modulating epigenetic events in the breast cancer cell line MDA-MB-231.
Oct 17, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Nutrigenet Nutrigenomics. 2017 Oct 18 ;10(3-4):126-135. Epub 2017 Oct 18. PMID:
29040973
Article Published Date
: Oct 17, 2017
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
,
Sulforaphane
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Epigenetic Modification In Cancer
[+]
In vitro effects of sulforaphane on interferon-driven inflammation and exploratory evaluation in two healthy volunteers.
Jun 11, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2021 Jun 12 ;26(12). Epub 2021 Jun 12. PMID:
34204601
Article Published Date
: Jun 11, 2021
Study Type
: Human In Vitro, Human Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Accumulation of sulforaphane and alliin in human prostate tissue.
Aug 09, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2022 Aug 10 ;14(16). Epub 2022 Aug 10. PMID:
36014767
Article Published Date
: Aug 09, 2022
Study Type
: Human Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
,
Sulforaphane
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Antioxidants
,
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
Acetylcysteine is beneficial in treating idiopathic pulmonary fibrosis. - Article 2
Sep 01, 1995
Click here to read the entire abstract
Pubmed Data
: Thorax. 1995 Sep;50 Suppl 1:S53-8. PMID:
7570466
Article Published Date
: Sep 01, 1995
Study Type
: Human Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
Diseases
:
Interstitial Lung Diseases
[+]
After 4 weeks consuming broccoli sprouts powder it resulted in a significant decrease in serum insulin concentration in patients.
Oct 31, 2012
Click here to read the entire abstract
Pubmed Data
: Int J Food Sci Nutr. 2012 Nov ;63(7):767-71. Epub 2012 Apr 26. PMID:
22537070
Article Published Date
: Oct 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Broccoli Sprouts
,
Sulforaphane
Diseases
:
Diabetes Mellitus: Type 2
,
Hyperinsulinism
,
Insulin Resistance
Pharmacological Actions
:
Antioxidants
,
Insulin Down-Regulation
[+]
Allicin extract and sodium bicarbonate may be suitable as drug alternatives in prevention of thrush in newborn infants.
Jan 01, 1992
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Xi Yi Jie He Za Zhi. 1992 Jan;12(1):28-9, 6. PMID:
1320966
Article Published Date
: Jan 01, 1992
Study Type
: Human Study
Additional Links
Substances
:
Allicin
,
Sodium Bicarbonate
Diseases
:
Thrush
[+]
Allicin improves carotid artery intima-media thickness in coronary artery disease patients with hyperhomocysteinemia.
Jul 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2017 Aug ;14(2):1722-1726. Epub 2017 Jun 28. PMID:
28810641
Article Published Date
: Jul 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Allicin
Diseases
:
Hyperhomocysteinemia
Pharmacological Actions
:
Anticholesteremic Agents
,
Cardioprotective
[+]
Broccoli sprout homogenate is safe in stable SCD patients and may induce changes in gene expression levels.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2016 ;11(4):e0152895. Epub 2016 Apr 12. PMID:
27071063
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Broccoli Sprouts
,
Sulforaphane
Diseases
:
Anemia: Sickle Cell
Additional Keywords
:
Gene Expression Regulation
[+]
Broccoli sprouts may enhance detoxication of airborne pollutants and attenuate their associated health risks.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2012 Jan ;33(1):101-7. Epub 2011 Nov 1. PMID:
22045030
Article Published Date
: Dec 31, 2011
Study Type
: Human Study
Additional Links
Substances
:
Broccoli Sprouts
,
Sulforaphane
Diseases
:
Air Pollution Linked Toxicity
,
DNA damage
Additional Keywords
:
Isothiocyanates
[+]
Broccoli sprouts reduce colonization and attenuate gastritis in Helicobacter pylori-infected mice and humans.
Apr 01, 2009
Click here to read the entire abstract
Pubmed Data
: Cancer Prev Res (Phila Pa). 2009 Apr;2(4):353-60. PMID:
19349290
Article Published Date
: Apr 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Broccoli
,
Broccoli Sprouts
,
Sprouts
,
Sulforaphane
Diseases
:
Gastritis
,
Helicobacter Pylori Infection
[+]
Consumption of broccoli sprouts modulated the excretion of biomarkers linked to inflammation and vascular reactions.
Apr 14, 2015
Click here to read the entire abstract
Pubmed Data
: Food Chem. 2015 Apr 15 ;173:1187-94. Epub 2014 Nov 7. PMID:
25466142
Article Published Date
: Apr 14, 2015
Study Type
: Human Study
Additional Links
Substances
:
Broccoli Sprouts
,
Sulforaphane
Diseases
:
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Cystine (a dipeptide of cysteine) and theanine supplementation restores high-Intensity resistance exercise-induced atenuation of natural killer cell activity in well-trained men.
Feb 09, 2010
Click here to read the entire abstract
Pubmed Data
: J Strength Cond Res. 2010 Feb 9. Epub 2010 Feb 9. PMID:
20145562
Article Published Date
: Feb 09, 2010
Study Type
: Human Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
,
Theanine
Diseases
:
Athletic Performance: Recovery
,
Immune Disorders: Low Immune Function
[+]
Daily administration of free sulforaphane shows promise in managing biochemical recurrences in prostate cancer after radical prostatectomy.
May 11, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Prev Res (Phila). 2015 May 12. Epub 2015 May 12. PMID:
25968598
Article Published Date
: May 11, 2015
Study Type
: Human Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Prostate: PSA Doubling
,
Radical Prostatectomy
Additional Keywords
:
Recurrence Risk
,
Significant Treatment Outcome
[+]
Effect of a sulforaphane supplement on muscle soreness and damage induced by eccentric exercise.
Jan 11, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Physiol Rep. 2021 12 ;9(24):e15130. PMID:
34927380
Article Published Date
: Jan 11, 2021
Study Type
: Human Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Muscle Soreness: Exercise-Induced
,
Oxidative Stress
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Nrf2 activation
[+]
Effect of supplemental antioxidant-based therapy on the oxidative stress level in COVID-19 patients.
Feb 28, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2023 Mar 1 ;44(1):7-16. Epub 2023 Mar 29. PMID:
36987766
Article Published Date
: Feb 28, 2023
Study Type
: Human Study
Additional Links
Substances
:
Lycopene
,
Reishi Mushroom
,
Resveratrol
,
Sulforaphane
Diseases
:
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Effects of sulforaphane intake on processing speed and negative moods in healthy older adults.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Aging Neurosci. 2022 ;14:929628. Epub 2022 Jul 29. PMID:
35966784
Article Published Date
: Dec 31, 2021
Study Type
: Human Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Cognitive Decline/Dysfunction
,
Mood Disorders
Pharmacological Actions
:
Neuroprotective Agents
[+]
Efficacy of N-acetylcysteine, D-mannose and Morinda citrifolia to treat recurrent cystitis in breast cancer survivors.
Aug 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: In Vivo. 2017 Sep-Oct;31(5):931-936. PMID:
28882961
Article Published Date
: Aug 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
,
D-Mannose
,
Noni
Diseases
:
Cystitis
[+]
Efficacy of sulforaphane in treatment of children with autism spectrum disorder.
Nov 23, 2022
Click here to read the entire abstract
Pubmed Data
: J Autism Dev Disord. 2022 Nov 24. Epub 2022 Nov 24. PMID:
36427174
Article Published Date
: Nov 23, 2022
Study Type
: Human Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Autism Spectrum Disorders
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
[+]
Evaluation of biodistribution of sulforaphane after administration of oral broccoli sprout extract in melanoma patients.
Apr 23, 2018
Click here to read the entire abstract
Pubmed Data
: Cancer Prev Res (Phila). 2018 Apr 24. Epub 2018 Apr 24. PMID:
29691233
Article Published Date
: Apr 23, 2018
Study Type
: Human Study
Additional Links
Substances
:
Broccoli Sprouts
,
Sulforaphane
Diseases
:
Melanoma
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemopreventive
[+]
Identification of urinary metabolites that correlate with clinical improvements in children with autism treated with sulforaphane from broccoli.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Autism. 2018 ;9:35. Epub 2018 May 30. PMID:
29854372
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Autism Spectrum Disorders
Pharmacological Actions
:
Antioxidants
[+]
L-cystine and l-theanine may contribute to enhancing the immune response against the H1N1 virus.
Dec 01, 2008
Click here to read the entire abstract
Pubmed Data
: Geriatr Gerontol Int. 2008 Dec;8(4):243-50. PMID:
19149835
Article Published Date
: Dec 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
,
Theanine
Diseases
:
Influenza in Swine
,
Swine Flu Associated Virus
Additional Keywords
:
Drug-Plant-Vitamin Synergies
[+]
Methylsulfonylmethane and boswellic acids versus glucosamine sulfate in the treatment of knee arthritis
Feb 29, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Immunopathol Pharmacol. 2016 Mar ;29(1):140-6. Epub 2015 Dec 18. PMID:
26684635
Article Published Date
: Feb 29, 2016
Study Type
: Human Study
Additional Links
Substances
:
Frankincense
,
MSM (Methylsulfonylmethane)
Diseases
:
Osteoarthritis: Knee
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
[+]
Methylsulfonylmethane appears to dampen the release of inflammatory molecules in response to exercise.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Sports Med (Hindawi Publ Corp). 2016 ;2016:7498359. Epub 2016 Oct 23. PMID:
27844051
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Inflammation
,
Muscle Damage: Exercise-Induced
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Methylsulfonylmethane may favourably influence selected markers of exercise recovery.
Sep 26, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Int Soc Sports Nutr. 2012 Sep 27 ;9(1):46. Epub 2012 Sep 27. PMID:
23013531
Article Published Date
: Sep 26, 2012
Study Type
: Human Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Athletic Performance: Recovery
Therapeutic Actions
:
Exercise
[+]
MSM contributes to the improvement of the symptoms of rosacea.
Mar 01, 2008
Click here to read the entire abstract
Pubmed Data
: J Cosmet Dermatol. 2008 Mar;7(1):8-14. PMID:
18254805
Article Published Date
: Mar 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Milk Thistle
,
MSM (Methylsulfonylmethane)
Diseases
:
Rosacea
[+]
MSM improves symptoms of pain and physical function in those with osteoarthritis.
Mar 01, 2006
Click here to read the entire abstract
Pubmed Data
: Osteoarthritis Cartilage. 2006 Mar;14(3):286-94. Epub 2005 Nov 23. PMID:
16309928
Article Published Date
: Mar 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Osteoarthritis
[+]
MSM relieves symptoms in the treatment of seasonal allergic rhinitis.
Apr 01, 2002
Click here to read the entire abstract
Pubmed Data
: J Altern Complement Med. 2002 Apr;8(2):167-73. PMID:
12006124
Article Published Date
: Apr 01, 2002
Study Type
: Human Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Allergic Rhinitis
[+]
MSM supplementation has therapeutic value in osteoarthritis.
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: BMC Complement Altern Med. 2011 ;11:50. Epub 2011 Jun 27. PMID:
21708034
Article Published Date
: Jan 01, 2011
Study Type
: Human Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Osteoarthritis
[+]
N-acetyl cysteine appears to be a safe and moderately effective augmentation strategy in chronic schizophrenia.
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: Biol Psychiatry. 2008 Sep 1;64(5):361-8. Epub 2008 Apr 23. PMID:
18436195
Article Published Date
: Sep 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
Diseases
:
Schizophrenia
[+]
N-acetylcysteine could be associated with a reduction in depressive symptoms.
Dec 03, 2018
Click here to read the entire abstract
Pubmed Data
: J Clin Psychiatry. 2018 Dec 4 ;80(1). Epub 2018 Dec 4. PMID:
30549489
Article Published Date
: Dec 03, 2018
Study Type
: Human Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
Diseases
:
Bipolar Disorder
,
Depression
Pharmacological Actions
:
Antidepressive Agents
Problem Substances
:
Aspirin
[+]
Optimized curcumin, pomegranate extract, and methylsulfonylmethane reduce acute, systemic inflammatory response to a half-marathon race.
Jun 30, 2020
Click here to read the entire abstract
Pubmed Data
: Altern Ther Health Med. 2020 Jul 1. Epub 2020 Jul 1. PMID:
32619204
Article Published Date
: Jun 30, 2020
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
,
MSM (Methylsulfonylmethane)
,
Pomegranate
Diseases
:
Inflammation
,
Muscle Damage: Exercise-Induced
Therapeutic Actions
:
Exercise: Running
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Oral chronic sulforaphane effects on heavy resistance exercise.
Sep 30, 2021
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2021 Oct ;90:111266. Epub 2021 Apr 7. PMID:
34004418
Article Published Date
: Sep 30, 2021
Study Type
: Human Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Muscle Damage: Exercise-Induced
Therapeutic Actions
:
Exercise: Resistance Training
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Oral sulforaphane safely and effectively induces mucosal Phase II enzyme expression in the upper airway of human subjects.
Mar 01, 2009
Click here to read the entire abstract
Pubmed Data
: Clin Immunol. 2009 Mar;130(3):244-51. Epub 2008 Nov 22. PMID:
19028145
Article Published Date
: Mar 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
COPD
,
Cystic Fibrosis
,
Glutathione Deficiency
,
Lung Diseases
,
Pulmonary Fibrosis
,
Respiratory Diseases
Pharmacological Actions
:
Antioxidants
,
Glutathione Upregulation
,
Phase II Detoxification Enzyme Inducer
Additional Keywords
:
Isothiocyanates
[+]
Oral supplementation of MSM has alleviating effects on known markers of oxidative stress following acute bouts of exercise in healthy young men.
Oct 01, 2011
Click here to read the entire abstract
Pubmed Data
: J Pharm Pharmacol. 2011 Oct ;63(10):1290-4. Epub 2011 Aug 1. PMID:
21899544
Article Published Date
: Oct 01, 2011
Study Type
: Human Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Athletic Performance: Recovery
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Glutathione Upregulation
[+]
Polyphenol and methylsulfonylmethane supplementation improves immune, DAMP signaling, and inflammatory responses during recovery from all-out running efforts.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Physiol. 2021 ;12:712731. Epub 2021 Aug 31. PMID:
34531760
Article Published Date
: Dec 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
,
MSM (Methylsulfonylmethane)
,
Polyphenols
,
Pomegranate Polyphenols
Diseases
:
Inflammation
Therapeutic Actions
:
Exercise: Running
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Raw broccoli results in faster absorption, higher bioavailability, and higher peak plasma amounts of sulforaphane, compared to cooked broccoli.
Nov 26, 2008
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2008 Nov 26;56(22):10505-9. PMID:
18950181
Article Published Date
: Nov 26, 2008
Study Type
: Human Study
Additional Links
Substances
:
Broccoli
,
Sulforaphane
Pharmacological Actions
:
Anticarcinogenic Agents
Additional Keywords
:
Raw versus Cooked
[+]
Safety Study: Brocolli sprouts (sulforaphane) are safe, tolerable and do not adversely effect thyroid hormone levels.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2006;55(1):53-62. PMID:
16965241
Article Published Date
: Jan 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Broccoli
,
Sprouts
,
Sulforaphane
Pharmacological Actions
:
Anticarcinogenic Agents
Additional Keywords
:
Isothiocyanates
,
Plant Extracts
[+]
Sulforaphane as an adjunctive treatment for irritability in children with autism spectrum disorder.
Apr 28, 2020
Click here to read the entire abstract
Pubmed Data
: Psychiatry Clin Neurosci. 2020 Apr 29. Epub 2020 Apr 29. PMID:
32347624
Article Published Date
: Apr 28, 2020
Study Type
: Human Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Autism Spectrum Disorders
Pharmacological Actions
:
Neuroprotective Agents
[+]
Sulforaphane detoxifies benzene, an air pollutant, in a dose-dependent manner and may attentuate attenuate associated long-term health risks of air pollution.
Jul 03, 2019
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2019 Jul 3. Epub 2019 Jul 3. PMID:
31268126
Article Published Date
: Jul 03, 2019
Study Type
: Human Study
Additional Links
Substances
:
Broccoli Sprouts
,
Sulforaphane
Diseases
:
Air Pollution Linked Toxicity
,
Benzene Toxicity
Pharmacological Actions
:
Antioxidant Effects
,
Detoxifier
Additional Keywords
:
Airborne Pollution
,
Broccoli
,
Broccoli Sprouts
,
Cruciferous Vegetables
,
Dose Response
,
Environmental Pollutant
,
Environmental Pollution
Problem Substances
:
Airborne Pollution
,
Benzene
[+]
Sulforaphane from broccoli was able to reduce some of the symptoms of autism.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Glob Adv Health Med. 2017 ;6:2164957X17735826. Epub 2017 Oct 26. PMID:
29147630
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Autism
[+]
Sulforaphane has a novel chemopreventive mechanism in human colon cancer cells and prostate epithelial cells, namely the inhibition of histone deacetylase (HDAC). I
Feb 01, 2007
Click here to read the entire abstract
Pubmed Data
: Exp Biol Med (Maywood). 2007 Feb;232(2):227-34. PMID:
17259330
Article Published Date
: Feb 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Colon Cancer
,
Prostate Cancer
,
Prostate Cancer: Prevention
Pharmacological Actions
:
Chemopreventive
,
Enzyme Inhibitors
,
Histone deacetylase inhibitor
[+]
Sulforaphane may improve endothelial function and blood pressure in women with pregnancy hypertension.
Apr 30, 2021
Click here to read the entire abstract
Pubmed Data
: Reprod Sci. 2021 May ;28(5):1489-1497. Epub 2021 Jan 6. PMID:
33409874
Article Published Date
: Apr 30, 2021
Study Type
: Human Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
[+]
Sulforaphane promotes white matter plasticity and improves long-term neurological outcomes after ischemic stroke.
Nov 19, 2022
Click here to read the entire abstract
Pubmed Data
: Free Radic Biol Med. 2022 Nov 20 ;193(Pt 1):292-303. Epub 2022 Oct 13. PMID:
36244590
Article Published Date
: Nov 19, 2022
Study Type
: Human Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Stroke
Pharmacological Actions
:
Neuroplasticity enhancement
,
Neuroprotective Agents
,
Nrf2 activation
Additional Keywords
:
Isothiocyanates
[+]
Sulforaphane protects against chemically-induced damage in bladder cells and tissues.
Jan 01, 2003
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2003 Jan;17(1):66-9. PMID:
20810543
Article Published Date
: Jan 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Bladder Cancer
,
Bladder Degeneration
,
DNA damage
Pharmacological Actions
:
Chemopreventive
,
Genoprotective
[+]
Sulforaphane treatment resulted in a significant reduction in specific airway resistance and also increased small airway luminal area.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Respir Res. 2015 ;16:106. Epub 2015 Sep 15. PMID:
26369337
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Broccoli Sprouts
,
Sulforaphane
Diseases
:
Asthma
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Nrf2 activation
Additional Keywords
:
Gene Expression Regulation
,
Plant Extracts
[+]
Sulforaphane-containing broccoli sprout extracts induce a cytoprotective phase 2 response in mouse and human skin.
Apr 01, 2007
Click here to read the entire abstract
Pubmed Data
: Cancer Epidemiol Biomarkers Prev. 2007 Apr;16(4):847-51. PMID:
17416783
Article Published Date
: Apr 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Broccoli
,
Sulforaphane
Diseases
:
Skin Diseases
Pharmacological Actions
:
Phase II Detoxification Enzyme Inducer
Additional Keywords
:
Plant Extracts
[+]
Sulforaphane-rich broccoli sprout extract attenuates nasal allergic response to diesel exhaust particles.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2014 Jan ;5(1):35-41. PMID:
24287881
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Broccoli Sprouts
,
Sulforaphane
Diseases
:
Diesel Exhaust Particle Toxicity
Pharmacological Actions
:
Anti-Allergic Agents
Additional Keywords
:
Isothiocyanates
,
Plant Extracts
[+]
Sulforaphane’s capacity to activate the Keap1–Nrf2 cytoprotective signaling pathway, and may protect against environmental and endogenous risk factors in autism spectrum disorders.
Oct 27, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Proc Natl Acad Sci U S A. 2014 Oct 28 ;111(43):15550-5. Epub 2014 Oct 13. PMID:
25313065
Article Published Date
: Oct 27, 2014
Study Type
: Human Study
Additional Links
Substances
:
Broccoli Sprouts
,
Isothiocyanates
,
Sulforaphane
Diseases
:
Autism Spectrum Disorders
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cytoprotective
,
Neuroprotective Agents
,
Nrf2 activation
Additional Keywords
:
Risk Factors
[+]
Supplementation therapy of sulforaphane rich broccoli sprout extract may have the potential to improve cognitive deficits in patients with schizophrenia.
Apr 29, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Clin Psychopharmacol Neurosci. 2015 Apr 30 ;13(1):62-7. PMID:
25912539
Article Published Date
: Apr 29, 2015
Study Type
: Human Study
Additional Links
Substances
:
Broccoli Sprouts
,
Sulforaphane
Diseases
:
Schizophrenia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
Additional Keywords
:
Plant Extracts
,
Significant Treatment Outcome
[+]
Supplementation with sulforaphane rich broccoli sprout extract could improve liver function through reduction of oxidative stress.
Nov 20, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Gastroenterol. 2015 Nov 21 ;21(43):12457-67. PMID:
26604653
Article Published Date
: Nov 20, 2015
Study Type
: Human Study
Additional Links
Substances
:
Broccoli
,
Sulforaphane
Diseases
:
Fatty Liver
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Synergism of allicin in combination with itraconazole and terbinafine, which could be a reference for the treatment of tinea capitis due to M. canis.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Med (Lausanne). 2021 ;8:783086. Epub 2021 Nov 26. PMID:
34901093
Article Published Date
: Dec 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Allicin
Diseases
:
Tinea
Pharmacological Actions
:
Antifungal Agents
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
The bioavailability of isothiocyanates from fresh broccoli is approximately three times greater than that from cooked broccoli,
Jan 01, 2000
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2000;38(2):168-78. PMID:
11525594
Article Published Date
: Jan 01, 2000
Study Type
: Human Study
Additional Links
Substances
:
Broccoli
,
Sulforaphane
Pharmacological Actions
:
Anticarcinogenic Agents
Additional Keywords
:
Raw versus Cooked
[+]
The bioavailability of sulforaphane from glucoraphanin supplements was equal to that from broccoli sprouts.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(11):e0140963. Epub 2015 Nov 2. PMID:
26524341
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Broccoli
,
Sulforaphane
Additional Keywords
:
Food Vs. Supplement
,
Increased Bioavailability
,
Plant Extracts
[+]
The effect of daily methylsulfonylmethane (MSM) consumption on high-density lipoprotein cholesterol.
Oct 14, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2021 Oct 15 ;13(10). Epub 2021 Oct 15. PMID:
34684621
Article Published Date
: Oct 14, 2021
Study Type
: Human Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Inflammation
,
Obesity
,
Overweight
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticholesteremic Agents
,
Antioxidants
[+]
The garlic compound allicin improves Helicobacter pylori eradication outcomes in patients who are HP positive in biopsy.
Jan 01, 2001
Click here to read the entire abstract
Pubmed Data
: Acta Medica (Hradec Kralove). 2001;44(3):97-100. PMID:
11811084
Article Published Date
: Jan 01, 2001
Study Type
: Human Study
Additional Links
Substances
:
Allicin
Diseases
:
Helicobacter Pylori Infection
Additional Keywords
:
Drug-Plant-Vitamin Synergies
[+]
The methylsulfonylmethane study product provided significant relief of allergic rhinitis symptoms.
Nov 28, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: JMIR Res Protoc. 2018 Nov 29 ;7(11):e11139. Epub 2018 Nov 29. PMID:
30497995
Article Published Date
: Nov 28, 2018
Study Type
: Human Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Allergic Rhinitis
Pharmacological Actions
:
Anti-Allergic Agents
[+]
The results of this study found that dosing twice a day may be important for increasing or prolonging certain chemopreventive benefits associated with sulforaphane consumption.
Feb 28, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Nutr Food Res. 2015 Mar ;59(3):424-33. Epub 2015 Jan 22. PMID:
25522265
Article Published Date
: Feb 28, 2015
Study Type
: Human Study
Additional Links
Substances
:
Cruciferous Vegetables
,
Sulforaphane
Diseases
:
Cancers: All
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Absorption
,
Bioavailability
,
Dietary Modification
[+]
Theanine/cysteine intake suppresses exercise-induced neutrophilia and lymphopenia in athletes.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Int Soc Sports Nutr. 2010;7(1):23. Epub 2010 Jun 4. PMID:
20525371
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
,
Theanine
Diseases
:
Athletic Performance
,
Athletic Performance: Recovery
,
Lymphopenia
,
Neutrophils: Elevated
[+]
This data suggest the therapeutic effect of allicin (L-cysteine) on COVID-19.
Jun 17, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Eur J Transl Myol. 2021 Jun 18 ;31(2). Epub 2021 Jun 18. PMID:
34148335
Article Published Date
: Jun 17, 2021
Study Type
: Human Study
Additional Links
Substances
:
Allicin
Diseases
:
Coronavirus Infection
Pharmacological Actions
:
Antiviral Agents
[+]
Week-long oral administration of sulforaphane increased blood and thalamic glutathione levels in healthy human subjects.
May 01, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Neuropsychiatry. 2018 May ;3(4):214-222. Epub 2018 Apr 17. PMID:
29888232
Article Published Date
: May 01, 2018
Study Type
: Human Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Psychiatric Disorders
Pharmacological Actions
:
Glutathione Upregulation
Additional Keywords
:
Broccoli
,
Broccoli Sprouts
,
Cruciferous Vegetables
,
psychiatric disorders
[+]
A diet rich in sulforaphane and related mustard oils may be considered as a supportive nutritional strategy to enhance therapeutic efficacy in patients suffering from pancreatic cancer.
Mar 29, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2014 Mar 30 ;5(6):1621-34. PMID:
24742583
Article Published Date
: Mar 29, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Cruciferous Vegetables
,
Sulforaphane
Diseases
:
Cancers: Drug Resistant
,
Pancreatic Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Chemotherapeutic
Additional Keywords
:
Cancer Stem Cells
,
Dietary Concentrations
[+]
Combination of epigallocatechin gallate and sulforaphane dounteracts In Vitro oxidative stress and delays stemness loss of amniotic fluid stem cells.
Jan 01, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2018 ;2018:5263985. Epub 2018 Dec 17. PMID:
30647811
Article Published Date
: Jan 01, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Catechin
,
Sulforaphane
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Regenerative
Additional Keywords
:
Isothiocyanates
[+]
Free radicals enhance the activation of Antioxidant Response Element (ARE) by sulforaphane, despite suppression of Nrf2 nuclear accumulation.
Jan 20, 2018
Click here to read the entire abstract
Pubmed Data
: Free Radic Biol Med. 2018 08 20 ;124:532-540. Epub 2018 Jun 30. PMID:
29969714
Article Published Date
: Jan 20, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidant Effects
,
Nrf2 activation
Additional Keywords
:
Antioxidants
,
Broccoli
,
Broccoli Sprouts
,
Cruciferous Vegetables
[+]
Methylsulfonylmethane and mobilee prevent negative effect of IL-1β in human chondrocyte cultures.
Nov 30, 2018
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2018 Dec ;65:129-139. Epub 2018 Oct 10. PMID:
30316071
Article Published Date
: Nov 30, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Protective role of allicin and L-ascorbic acid against the genotoxic damage induced by chlormadinone acetate.
Aug 31, 2005
Click here to read the entire abstract
Pubmed Data
: Indian J Exp Biol. 2005 Sep ;43(9):769-72. PMID:
16187526
Article Published Date
: Aug 31, 2005
Study Type
: Human In Vitro
Additional Links
Substances
:
Allicin
,
Vitamin C
Pharmacological Actions
:
Antioxidants
,
Cytoprotective
[+]
Sulforaphane attentuates cadmium-induced carcinogenesis through Nrf2, antioxidant, and autophagy mechanisms.
Jan 15, 2018
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2018 08 15 ;353:23-30. Epub 2018 Jun 6. PMID:
29885333
Article Published Date
: Jan 15, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Cadmium Poisoning
,
Cancers
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antioxidant
,
Antioxidant Effects
,
Apoptotic
,
Autophagy Up-regulation
,
NF-E2-Related Factor-2 (Nrf2) Modulator
Additional Keywords
:
Broccoli
,
Broccoli Sprouts
,
Cruciferous Vegetables
,
Isothiocyanates
[+]
Sulforaphane combats colon cancer in vitro by inhibiting COX-2 and prostaglandin E1 synthase and exhibiting anti-angiogenic, anti-proliferative, and anti-metastatic properties.
Jan 01, 2018
Click here to read the entire abstract
Pubmed Data
: Cells Tissues Organs. 2018 ;206(1-2):46-53. Epub 2018 Jul 24. PMID:
30041241
Article Published Date
: Jan 01, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-Angiogenic
,
Anti-cancer
,
Anti-metastatic
,
Anti-Proliferative
,
Cyclooxygenase 2 Inhibitors
,
Hypoxia-inducible factor-1 (HIF-1) inhibitor
,
Prostaglandin E Synthase-1 (PGES-1) Down-Regulation
Additional Keywords
:
Broccoli
,
Broccoli Sprouts
,
Cruciferous Vegetables
[+]
Sulforaphane decreases leukemia cell viability in vitro by inhibiting NADPH oxidase enzymes and redox transporter signaling.
Jan 01, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2018 ;2018:4125297. Epub 2018 Nov 18. PMID:
30581529
Article Published Date
: Jan 01, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Cruciferous Vegetables
,
Sulforaphane
Diseases
:
Leukemia
Pharmacological Actions
:
Antioxidant
,
Antioxidant Effects
,
Antiproliferative
,
NADPH Oxidase Inhibitors
Additional Keywords
:
Broccoli
,
Broccoli Sprouts
,
Isothiocyanates
[+]
Sulforaphane delays fibroblast aging in vitro by decreasing glycolysis and reducing oxidative stress.
Jan 01, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2018 ;2018:5642148. Epub 2018 Nov 22. PMID:
30595796
Article Published Date
: Jan 01, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Aging
,
Oxidative Stress
Pharmacological Actions
:
Nrf2 activation
Additional Keywords
:
calorie restriction
,
High Sugar Diet
,
Isothiocyanates
[+]
Sulforaphane improves mitochondrial metabolism in fibroblasts from patients with fragile X-associated tremor and ataxia syndrome.
Aug 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neurobiol Dis. 2021 Sep ;157:105427. Epub 2021 Jun 19. PMID:
34153466
Article Published Date
: Aug 31, 2021
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Ataxia
,
Fragile X Syndrome
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
Sulforaphane inhibits Wnt/β-catenin signaling in colorectal cancer cells, supressing proliferation and inducing cell death.
Sep 21, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2018 Sep 21 ;9(74):33982-33994. Epub 2018 Sep 21. PMID:
30338040
Article Published Date
: Sep 21, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Wnt/β-catenin pathway down-regulation
Additional Keywords
:
Anti-cancer
[+]
Sulforaphane may prevent or treat breast cancer by reversing estrogen-induced metabolic changes or alterations in methylation.
Dec 01, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: FEBS Open Bio. 2018 Dec ;8(12):2022-2034. Epub 2018 Nov 14. PMID:
30524952
Article Published Date
: Dec 01, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Breast Cancer: Estrogen
Additional Keywords
:
Estrogen Positive Breast Cancer
,
Folate
,
Methylation
[+]
Sulforaphane prevents hepatic insulin resistance through a ceramide-dependent mechanism.
May 27, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 May 27 ;11(5). Epub 2019 May 27. PMID:
31137828
Article Published Date
: May 27, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Broccoli Sprouts
,
Sulforaphane
Diseases
:
Diabetes Mellitus: Type 2
,
Insulin Disorders
,
Insulin Resistance
Pharmacological Actions
:
Glucose Uptake Optimization
,
Insulin Sensitizers
Additional Keywords
:
Broccoli
,
Cruciferous Vegetables
,
glucose control
,
Glucose Uptake Enhancement
[+]
Sulforaphane protected the injury of vascular endothelial cell by LPC by enhancing anti-oxidative capabilities mediated by Nrf-2 translocation.
May 25, 2015
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2015 May 26. Epub 2015 May 26. PMID:
26008201
Article Published Date
: May 25, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Endothelial Damage
,
Endothelial Dysfunction
Pharmacological Actions
:
Antioxidants
,
Phase II Detoxification Enzyme Inducer
,
Superoxide Dismutase Up-regulation
[+]
Sulforaphane protects against ethanol-induced apoptosis in neural crest cells, a characteristic of Fetal Alcohol Syndrome, through restoration of Snail1 expression and epithelial-mesenchymal transition.
Jul 08, 2019
Click here to read the entire abstract
Pubmed Data
: Biochim Biophys Acta Mol Basis Dis. 2019 Jul 8 ;1865(10):2586-2594. Epub 2019 Jul 8. PMID:
31295528
Article Published Date
: Jul 08, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Fetal Alcoholism
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
Additional Keywords
:
Alcohol
,
Broccoli
,
Broccoli Sprouts
,
Cruciferous Vegetables
,
Mesenchymal Stem Cells
,
Pregnancy And Fetal Growth
[+]
Sulforaphane protects against oxidative stress in culture of adult cardiomyocytes.
Aug 01, 2018
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2018 Aug ;104:165-171. Epub 2018 May 15. PMID:
29772437
Article Published Date
: Aug 01, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Nrf2 activation
Additional Keywords
:
Broccoli
,
Broccoli Sprouts
,
Cruciferous Vegetables
,
Isothiocyanates
[+]
Sulforaphane regulates xenobiotic metabolism phase II and III enzymes differently in colorectal cancer and untransformed epithelial colon cells.
Oct 31, 2016
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2016 Nov-Dec;68(8):1338-1348. Epub 2016 Aug 16. PMID:
27636860
Article Published Date
: Oct 31, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Colon Cancer
Pharmacological Actions
:
Cytoprotective
,
Nrf2 activation
Additional Keywords
:
Gene Expression Regulation
,
Selective Cytotoxicity
[+]
Sulforaphane rescues amyloid-β peptide-mediated decrease in MerTK expression through its anti-inflammatory effect.
Mar 11, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Neuroinflammation. 2018 Mar 12 ;15(1):75. Epub 2018 Mar 12. PMID:
29530050
Article Published Date
: Mar 11, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Sulforaphane suppresses proliferation and enhances apoptosis of gastric cancer stem cells in vitro.
Aug 01, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Food Sci Nutr. 2019 Aug ;70(5):570-578. Epub 2019 Jan 9. PMID:
30624124
Article Published Date
: Aug 01, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Gastric Cancer
,
Gastric Cancer: Prevention
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Anti-cancer
[+]
Sulforaphene inhibits liver cancer cell proliferation by stimulating apoptosis and causing cytotoxicity.
Jun 04, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2018 Jun 4 ;10(6). Epub 2018 Jun 4. PMID:
29866995
Article Published Date
: Jun 04, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Liver Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Broccoli
,
Broccoli Sprouts
,
Cruciferous Vegetables
,
Isothiocyanates
[+]
Sulforphane exhibits immunomodulatory properties on human placenta cells in vitro.
Feb 01, 2019
Click here to read the entire abstract
Pubmed Data
: J Reprod Immunol. 2019 Feb ;131:44-49. Epub 2018 Dec 29. PMID:
30641297
Article Published Date
: Feb 01, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Immune Enhancing Properties
Additional Keywords
:
Broccoli
,
Broccoli Sprouts
,
Cruciferous Vegetables
,
Pregnancy
[+]
The addition of broccoli and watercress in the diet may reduce risk of breast cancer
Dec 01, 2005
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2005 Dec 1 ;209(2):105-13. Epub 2005 Jun 13. PMID:
15953625
Article Published Date
: Dec 01, 2005
Study Type
: Human In Vitro
Additional Links
Substances
:
Broccoli
,
Sulforaphane
,
Watercress
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
Additional Keywords
:
Isothiocyanates
,
Plant Extracts
[+]
The protective effect of sulforaphane against oxidative stress.
Oct 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell J. 2021 Nov ;23(6):692-700. Epub 2021 Nov 23. PMID:
34939763
Article Published Date
: Oct 31, 2021
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Nrf2 activation
[+]
This study demonstrates that sulforaphane targets multiple signaling pathways to suppress ovarian cancer in vitro and in vivo.
Nov 01, 2018
Click here to read the entire abstract
Pubmed Data
: Int J Mol Med. 2018 Nov ;42(5):2447-2458. Epub 2018 Sep 6. PMID:
30226534
Article Published Date
: Nov 01, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Female
,
Ovarian Cancer
Pharmacological Actions
:
Anti-Tumor
,
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
HER-2 oncoprotein down-regulation
,
NF-kappaB Inhibitor
,
Tumor Suppressor Protein p53 Upregulation
Additional Keywords
:
Drug Synergy
,
Isothiocyanates
[+]
Diallyl trisulfide inhibits monosodium urate-induced NLRP3 inflammasome activation.
Mar 31, 2023
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2023 Apr ;112:154705. Epub 2023 Feb 9. PMID:
36796188
Article Published Date
: Mar 31, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Organosulfur Compounds
Diseases
:
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
[+]
In silico and in vitro analysis of sulforaphane anti-candida activity.
Dec 18, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antibiotics (Basel). 2022 Dec 19 ;11(12). Epub 2022 Dec 19. PMID:
36551499
Article Published Date
: Dec 18, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Candida Albicans
Pharmacological Actions
:
Antifungal Agents
,
Antimicrobial
Additional Keywords
:
Bacterial Infections: Resistance/Biofilm Formation
[+]
Lipid-based nanoparticle formulation of diallyl trisulfide chemosensitizes the growth inhibitory activity of doxorubicin in colorectal cancer.
Mar 27, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2022 Mar 28 ;27(7). Epub 2022 Mar 28. PMID:
35408590
Article Published Date
: Mar 27, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Organosulfur Compounds
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Apoptotic
,
Chemosensitizer
Additional Keywords
:
Chemotherapeutic Synergy: Doxorubicin
[+]
Sulforaphane ameliorates hepatic lipid metabolism.
Dec 06, 2022
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2022 Dec 7 ;70(48):15126-15133. Epub 2022 Nov 24. PMID:
36420856
Article Published Date
: Dec 06, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Hyperlipidemia
Pharmacological Actions
:
Hypolipidemic
[+]
Allicin reduces inflammation by regulating ROS/NLRP3 and autophagy in the context of A. fumigatus infection in mice.
Aug 07, 2020
Click here to read the entire abstract
Pubmed Data
: Gene. 2020 Aug 8 ;762:145042. Epub 2020 Aug 8. PMID:
32777529
Article Published Date
: Aug 07, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Allicin
Diseases
:
Aspergillosis
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
"Inhibition of bladder cancer by broccoli isothiocyanates sulforaphane and erucin."
Oct 31, 2012
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2012 Nov ;56(11):1675-87. Epub 2012 Oct 5. PMID:
23038615
Article Published Date
: Oct 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Erucin
,
Sulforaphane
Diseases
:
Bladder Cancer
Pharmacological Actions
:
Chemopreventive
[+]
"Inhibition of Epstein-Barr virus reactivation in nasopharyngeal carcinoma cells by dietary sulforaphane."
May 28, 2012
Click here to read the entire abstract
Pubmed Data
: Mol Carcinog. 2012 May 29. Epub 2012 May 29. PMID:
22641235
Article Published Date
: May 28, 2012
Study Type
: Insect Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Epstein-Barr Virus Infections
,
Nasopharyngeal Cancer
[+]
"Neuroprotective effects of sulforaphane after contusive spinal cord injury."
Oct 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Neurotrauma. 2012 Nov 1 ;29(16):2576-86. Epub 2012 Sep 20. PMID:
22853439
Article Published Date
: Oct 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Spinal Cord Injuries
Pharmacological Actions
:
Neuroprotective Agents
[+]
"Prevention of diabetic nephropathy by sulforaphane: possible role of Nrf2 upregulation and activation."
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2012 ;2012:821936. Epub 2012 Sep 23. PMID:
23050040
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Diabetic Nephropathy
[+]
"Protective effects of the antioxidant sulforaphane on behavioral changes and neurotoxicity in mice after the administration of methamphetamine."
Jun 30, 2012
Click here to read the entire abstract
Pubmed Data
: Psychopharmacology (Berl). 2012 Jul ;222(1):37-45. Epub 2011 Dec 27. PMID:
22200890
Article Published Date
: Jun 30, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Amphetamine Addiction/Withdrawal
,
Brain: Microglial Activation
,
Neurodegenerative Diseases
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
"Sulforaphane induces phase II detoxication enzymes in mouse skin and prevents mutagenesis induced by a mustard gas analog."
Nov 29, 2012
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2012 Nov 30. Epub 2012 Nov 30. PMID:
23201461
Article Published Date
: Nov 29, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Chemical Weapon Agent Injury
,
Skin Cancer: Prevention
Pharmacological Actions
:
Phase II Detoxification Enzyme Inducer
[+]
"Sulforaphane inhibits the growth of KPL-1 human breast cancer cells in vitro and suppresses the growth and metastasis of orthotopically transplanted KPL-1 cells in female athymic mice."
Sep 01, 2011
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2011 Sep ;26(3):603-8. Epub 2011 May 20. PMID:
21617865
Article Published Date
: Sep 01, 2011
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Breast Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
[+]
"ulforaphane Protects Small Intestinal Mucosa From Aspirin/NSAID-Induced Injury by Enhancing Host Defense Systems Against Oxidative Stress and by Inhibiting Mucosal Invasion of Anaerobic Enterobacteria."
Aug 22, 2012
Click here to read the entire abstract
Pubmed Data
: Curr Pharm Des. 2012 Aug 23. Epub 2012 Aug 23. PMID:
22950492
Article Published Date
: Aug 22, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Aspirin-Induced Toxicity
,
NSAID-induced toxicity
[+]
Acetaminophen-induced liver injury: Molecular mechanism and treatments from natural products.
Dec 31, 2022
Click here to read the entire abstract
Pubmed Data
: Front Pharmacol. 2023 ;14:1122632. Epub 2023 Mar 27. PMID:
37050900
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Polyphenols
,
Sulforaphane
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Acetaminophen
[+]
Addition of bromelain and acetylcysteine to gemcitabine potentiates tumor inhibition in vivo in human colon cancer cell line LS174T.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Cancer Res. 2021 ;11(5):2252-2263. Epub 2021 May 15. PMID:
34094682
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Bromelain
,
Cysteine (see N-Acetylcysteine)
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemosensitizer
Additional Keywords
:
Chemotherapeutic Synergy: Gemcitabine
[+]
Administration of N- acetylcysteine and genistein have an additive gastroprotective effect in indomethacin induced gastric injury.
Jul 15, 2018
Click here to read the entire abstract
Pubmed Data
: Can J Physiol Pharmacol. 2018 Jul 16. Epub 2018 Jul 16. PMID:
30011378
Article Published Date
: Jul 15, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
,
Genistein
Diseases
:
Drug-Induced Toxicity: Indomethacin
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Gastroprotective
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Age-related mitochondrial impairment and renal injury is ameliorated by sulforaphane.
Jan 13, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2022 Jan 14 ;11(1). Epub 2022 Jan 14. PMID:
35052660
Article Published Date
: Jan 13, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Aging
,
Kidney Damage
Pharmacological Actions
:
Nrf2 activation
,
Renoprotective
[+]
Allicin administration has the potential to protect against cyclosporine-A induced renal injury.
Jun 30, 2017
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2017 Jul ;36(7):681-691. Epub 2016 Sep 5. PMID:
27596067
Article Published Date
: Jun 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Drug-Induced Toxicity: Cyclosporine
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Renoprotective
Problem Substances
:
Cyclosporine
[+]
Allicin alleviated learning and memory deficits caused by lead exposure at developmental stage.
Jun 02, 2019
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2019 Jun 3. Epub 2019 Jun 3. PMID:
31170417
Article Published Date
: Jun 02, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Lead Poisoning
,
Memory Disorders
Pharmacological Actions
:
Neuroprotective Agents
Problem Substances
:
Lead
[+]
Allicin alleviates diabetes mellitus by inhibiting the formation of advanced glycation end products.
Dec 11, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2022 Dec 12 ;27(24). Epub 2022 Dec 12. PMID:
36557926
Article Published Date
: Dec 11, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Advanced Glycation End products (AGE)
,
Diabetes: Oxidative Stress
Pharmacological Actions
:
Anti-Glycation Agents
[+]
Allicin alleviates inflammation of diabetic macroangiopathy via the Nrf2 and NF-kB pathway.
Mar 01, 2020
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2020 Mar 2:173052. Epub 2020 Mar 2. PMID:
32135124
Article Published Date
: Mar 01, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Allicin
Diseases
:
Diabetic Complications
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
,
Nrf2 activation
[+]
Allicin alleviates lead-induced bone loss by preventing oxidative stress and osteoclastogenesis.
Apr 20, 2020
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2020 Apr 21. Epub 2020 Apr 21. PMID:
32314144
Article Published Date
: Apr 20, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Antioxidants
,
Osteoprotective
Problem Substances
:
Lead
[+]
Allicin ameliorates aluminium- and copper-induced cognitive dysfunction.
May 21, 2021
Click here to read the entire abstract
Pubmed Data
: J Biol Inorg Chem. 2021 May 22. Epub 2021 May 22. PMID:
34023945
Article Published Date
: May 21, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Aluminum Toxicity
,
Cognitive Decline/Dysfunction
,
Copper Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Allicin ameliorates cognitive impairment in APP/PS1 mice.
Jan 31, 2018
Click here to read the entire abstract
Pubmed Data
: Tissue Cell. 2018 Feb ;50:89-95. Epub 2017 Dec 2. PMID:
29429523
Article Published Date
: Jan 31, 2018
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Allicin ameliorates renal ischemia/reperfusion injury via inhibition of oxidative stress and inflammation.
Aug 22, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2021 Aug 23 ;142:112077. Epub 2021 Aug 23. PMID:
34426252
Article Published Date
: Aug 22, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Renoprotective
[+]
Allicin ameliorates sepsis-induced acute kidney injury.
Sep 04, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Nat Med. 2023 Sep 5. Epub 2023 Sep 5. PMID:
37668824
Article Published Date
: Sep 04, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Kidney Damage
,
Sepsis
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Nrf2 activation
,
Renoprotective
[+]
Allicin and omega-3 fatty acids attenuates acetaminophen mediated renal toxicity.
Jul 11, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Naunyn Schmiedebergs Arch Pharmacol. 2023 Jul 12. Epub 2023 Jul 12. PMID:
37436496
Article Published Date
: Jul 11, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
,
Omega-3 Fatty Acids
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Kidney Damage: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Renoprotective
Problem Substances
:
Acetaminophen
[+]
Allicin attenuated chronic social defeat stress induced depressive-like behaviors
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Metab Brain Dis. 2019 02 ;34(1):319-329. Epub 2018 Dec 4. PMID:
30515710
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
[+]
Allicin attenuated depressive-like behaviours triggered by long-term high fat diet consumption.
Jun 13, 2019
Click here to read the entire abstract
Pubmed Data
: Metab Brain Dis. 2019 Jun 14. Epub 2019 Jun 14. PMID:
31201726
Article Published Date
: Jun 13, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Depression
,
High Fat Diet
,
Obesity
Pharmacological Actions
:
Antidepressive Agents
,
Antioxidants
,
Nrf2 activation
[+]
Allicin attenuates calcium oxalate crystal deposition.
May 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Cell Physiol. 2019 Jun ;234(6):9640-9651. Epub 2018 Oct 30. PMID:
30378099
Article Published Date
: May 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Kidney Stones
[+]
Allicin attenuates early brain injury after experimental subarachnoid hemorrhage.
Feb 14, 2019
Click here to read the entire abstract
Pubmed Data
: J Clin Neurosci. 2019 Feb 15. Epub 2019 Feb 15. PMID:
30773476
Article Published Date
: Feb 14, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Subarachnoid hemorrhage
Pharmacological Actions
:
Neuroprotective Agents
[+]
Allicin attenuates lipopolysaccharide‑induced acute lung injury.
Mar 06, 2018
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2018 Mar 7. Epub 2018 Mar 7. PMID:
29512749
Article Published Date
: Mar 06, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Allicin attenuates liver oxidative stress and inflammation.
Sep 27, 2016
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2016 Sep 28 ;64(38):7104-13. Epub 2016 Sep 19. PMID:
27584700
Article Published Date
: Sep 27, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Alcohol Toxicity
,
Fatty Liver
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Alcohol Toxicity
,
Allicin
,
Anti-Inflammatory Agents
,
Fatty Liver
,
Inflammation
,
oxidative stress
[+]
Allicin can protect rats against myocardial ischemia reperfusion injury by suppressing inflammation and oxidative stress.
Jul 31, 2019
Click here to read the entire abstract
Pubmed Data
: Transplant Proc. 2019 Jul - Aug;51(6):2060-2065. PMID:
31399184
Article Published Date
: Jul 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Allicin can reduce oxidative stress damage and cardiomyocyte apoptosis in a model of myocardial infarction.
Aug 11, 2020
Click here to read the entire abstract
Pubmed Data
: Pharmacology. 2020 Aug 12:1-9. Epub 2020 Aug 12. PMID:
32784309
Article Published Date
: Aug 11, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Allicin could be a promising cytoprotective agent against doxorubicin cardiotoxicity.
Aug 06, 2017
Click here to read the entire abstract
Pubmed Data
: Cancer Chemother Pharmacol. 2017 Aug 7. Epub 2017 Aug 7. PMID:
28785995
Article Published Date
: Aug 06, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
,
Garlic
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
[+]
Allicin could be promising for the treatment of human cutaneous leishmaniasis and the control of secondary bacterial infections.
Jul 12, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Environ Res Public Health. 2017 Jul 13 ;14(7). Epub 2017 Jul 13. PMID:
28703780
Article Published Date
: Jul 12, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Allicin
Diseases
:
Leishmaniasis
Pharmacological Actions
:
Leishmanicidal
[+]
Allicin could be used as a novel supplementary cardioprotective therapy to avoid trastuzumab-induced cardiotoxicity.
May 20, 2022
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2022 May 21 ;302:120656. Epub 2022 May 21. PMID:
35605695
Article Published Date
: May 20, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Chemotherapy and Radiation Toxicity
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
[+]
Allicin could be used as a pharmacologic treatment in tunicamycin induced cognitive deficits.
May 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Iran J Basic Med Sci. 2017 Jun ;20(6):676-682. PMID:
28868122
Article Published Date
: May 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Antibiotic Toxicity
Pharmacological Actions
:
Neuroprotective Agents
Problem Substances
:
Antibiotics
[+]
Allicin could be used in protection in traumatic spinal cord injury.
Sep 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2016 Oct ;14(4):3086-92. Epub 2016 Aug 19. PMID:
27573340
Article Published Date
: Sep 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Oxidative Stress
,
Spinal Cord Injuries
Pharmacological Actions
:
Antioxidants
,
Heat Shock Protein Inducer
,
Neuroprotective Agents
Additional Keywords
:
Allicin
,
Antioxidants
,
Heat Shock Protein Inducer
,
Neuroprotective Agents
,
oxidative stress
,
Spinal Cord Injuries
[+]
Allicin could decrease blood glucose level, improve islet structure and insulin expression, and inhibit apoptosis to reduce STZ-induced pancreatic β cell injury.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Front Pharmacol. 2023 ;14:1108730. Epub 2023 Feb 3. PMID:
36817124
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Diabetes Mellitus: Type 1
Pharmacological Actions
:
Anti-Apoptotic
,
Hypoglycemic Agents
,
Pancreato Protective Agents
[+]
Allicin delays the progression of diabetic nephropathy through antioxidant and anti-inflammatory mechanisms.
Oct 10, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2018 Oct 11 ;19(10). Epub 2018 Oct 11. PMID:
30314265
Article Published Date
: Oct 10, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Allicin
,
Garlic
Diseases
:
Diabetic Nephropathy
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Allicin enhances antimicrobial activity of macrophages during Mycobacterium tuberculosis infection.
Dec 07, 2018
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2018 Dec 8. Epub 2018 Dec 8. PMID:
30537531
Article Published Date
: Dec 07, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Allicin
Diseases
:
Mycobacterium Tuberculosis
[+]
Allicin exhibits antitumor activity in mouse lymphoma.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Asian Pac J Cancer Prev. 2010 ;11(5):1241-4. PMID:
21198270
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Lymphoma
Pharmacological Actions
:
Anti-Proliferative
,
Apoptotic
[+]
Allicin has antileishmanial effects under in vitro and in vivo conditions and may be used in clinical applications.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2016 ;11(8):e0161296. Epub 2016 Aug 18. PMID:
27537199
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Allicin
Diseases
:
Leishmaniasis
Pharmacological Actions
:
Leishmanicidal
Additional Keywords
:
Allicin
,
Leishmaniasis
,
Leishmanicidal
[+]
Allicin has powerful protective effects against ischemia/hypoxia-induced cell apoptosis.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2018 ;2018:3207973. Epub 2018 Apr 16. PMID:
29849702
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Heme oxygenase-1 up-regulation
,
Superoxide Dismutase Up-regulation
[+]
Allicin has the potential to help in the treatment of diabetic nephropathy.
Nov 14, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2020 Nov 15 ;9(11). Epub 2020 Nov 15. PMID:
33203103
Article Published Date
: Nov 14, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Diabetic Nephropathy
Pharmacological Actions
:
Anti-Fibrotic
,
Antioxidants
,
Renoprotective
[+]
Allicin have the effective hepato-protection on ethanol-induced hepatotoxicity.
Nov 29, 1998
Click here to read the entire abstract
Pubmed Data
: Wei Sheng Yan Jiu. 1998 Nov 30 ;27(6):415-7. PMID:
11939034
Article Published Date
: Nov 29, 1998
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Alcoholic Liver Disease
Pharmacological Actions
:
Hepatoprotective
[+]
Allicin improves cardiac function by protecting against apoptosis in rat model of myocardial infarction.
Jul 31, 2017
Click here to read the entire abstract
Pubmed Data
: Chin J Integr Med. 2017 Aug ;23(8):589-597. Epub 2016 Jul 13. PMID:
27412589
Article Published Date
: Jul 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
Additional Keywords
:
Allicin
,
Anti-Apoptotic
,
Cardioprotective
,
Myocardial Infarction
[+]
Allicin improves metabolism in high-fat diet-induced obese mice by modulating the gut microbiota.
Dec 01, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Dec 2 ;11(12). Epub 2019 Dec 2. PMID:
31810206
Article Published Date
: Dec 01, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Obesity
Pharmacological Actions
:
Gastrointestinal Agents
Additional Keywords
:
Anti-Obesity Agents
[+]
Allicin in garlic protects against coronary endothelial dysfunction and right heart hypertrophy in pulmonary hypertensive rats.
Nov 01, 2006
Click here to read the entire abstract
Pubmed Data
: Am J Physiol Heart Circ Physiol. 2006 Nov;291(5):H2431-8. Epub 2006 May 26. PMID:
16731642
Article Published Date
: Nov 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
,
Garlic
Diseases
:
Endothelial Dysfunction
,
Hypertension: Pulmonary
,
Right Ventricular Hypertrophy
Additional Keywords
:
Plant Extracts
[+]
Allicin inhibits mouse colorectal tumorigenesis through suppressing the activation of STAT3 signaling pathway.
Apr 22, 2018
Click here to read the entire abstract
Pubmed Data
: Nat Prod Res. 2018 Apr 23:1-4. Epub 2018 Apr 23. PMID:
29683343
Article Published Date
: Apr 22, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Allicin
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
,
STAT3 Activation
[+]
Allicin inhibits the proliferation and invasion in cholangiocarcinoma.
May 21, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Cell Physiol Biochem. 2018 May 22 ;47(2):641-653. Epub 2018 May 22. PMID:
29794468
Article Published Date
: May 21, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Allicin
Diseases
:
Cholangiocarcinoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Allicin is a promising therapeutic approach for the treatment of obesity and metabolic disorders.
May 21, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: iScience. 2020 May 22 ;23(5):101113. Epub 2020 Apr 28. PMID:
32413611
Article Published Date
: May 21, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Hepatic Steatosis
,
Obesity
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Anti-Obesity Agents
[+]
Allicin is highly effective in the treatment and prevention of acrylamide-induced intestinal injury.
Oct 24, 2021
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2021 Oct 25. Epub 2021 Oct 25. PMID:
34694121
Article Published Date
: Oct 24, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Acrylamide-induced toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Gastroprotective
Problem Substances
:
Acrylamide
[+]
Allicin may ameliorate sepsis-induced acute lung injury in mice by enhancing the level of autophagy.
Aug 27, 2017
Click here to read the entire abstract
Pubmed Data
: Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2017 Aug 28 ;42(8):899-905. PMID:
28872080
Article Published Date
: Aug 27, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Sepsis
Pharmacological Actions
:
Autophagy Up-regulation
[+]
Allicin may be an alternative in treating pulmonary arterial hypertension.
Aug 18, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2023 Aug 19 ;24(16). Epub 2023 Aug 19. PMID:
37629140
Article Published Date
: Aug 18, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Pulmonary Hypertension
Pharmacological Actions
:
Antihypertensive Agents
[+]
Allicin may be useful in preventing cisplatin-induced ototoxicity.
Jul 23, 2019
Click here to read the entire abstract
Pubmed Data
: ORL J Otorhinolaryngol Relat Spec. 2019 Jul 24:1-13. Epub 2019 Jul 24. PMID:
31340214
Article Published Date
: Jul 23, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
[+]
Allicin may be useful in preventing oto-vestibulotoxicity mediated by cisplatin.
Jun 14, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2017 Jun 15 ;805:108-117. Epub 2017 Mar 1. PMID:
28259711
Article Published Date
: Jun 14, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
[+]
Allicin may be useful in reducing oxidative stress, inflammation, vascular dysfunction, and the aortic pathology in hypercholesterolemic rabbits.
Aug 13, 2015
Click here to read the entire abstract
Pubmed Data
: Can J Physiol Pharmacol. 2015 Aug 14:1-9. Epub 2015 Aug 14. PMID:
26618400
Article Published Date
: Aug 13, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Endothelial Dysfunction
,
Inflammation
,
Obesity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Allicin may exhibit the cardiovascular disease protective effect through modulation of gut microbiota-TMAO-atherosclerosis pathway.
May 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Curr Dev Nutr. 2019 Jun ;3(Suppl 1). Epub 2019 Jun 13. PMID:
31223853
Article Published Date
: May 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Cardiovascular Diseases
Pharmacological Actions
:
Cardioprotective
,
Gastrointestinal Agents
[+]
Allicin may have therapeutic effects on lead poisoning.
Dec 01, 2008
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2008 Winter;126(1-3):141-7. Epub 2008 Aug 22. PMID:
18719860
Article Published Date
: Dec 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Lead Poisoning
[+]
Allicin may safeguard renal function in rats with chronic kidney disease.
Apr 30, 2023
Click here to read the entire abstract
Pubmed Data
: Iran J Kidney Dis. 2023 May ;17(3):135-140. PMID:
37337797
Article Published Date
: Apr 30, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Kidney Failure: Chronic
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
NF-kappaB Inhibitor
,
Renoprotective
,
Superoxide Dismutase Up-regulation
[+]
Allicin mitigates hepatic injury following cyclophosphamide administration.
Mar 23, 2021
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2021 Mar 24. Epub 2021 Mar 24. PMID:
33763830
Article Published Date
: Mar 23, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Hepatoprotective
,
Nrf2 activation
[+]
Allicin modifies the composition and function of the gut microbiota in alcoholic hepatic steatosis mice.
Mar 10, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Agric Food Chem. 2020 Mar 11 ;68(10):3088-3098. Epub 2020 Feb 27. PMID:
32050766
Article Published Date
: Mar 10, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Alcoholic Liver Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Allicin modulates diclofenac sodium induced hepatonephro toxicity.
Nov 22, 2019
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol Pharmacol. 2019 Nov 23 ;74:103306. Epub 2019 Nov 23. PMID:
31812117
Article Published Date
: Nov 22, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Pharmacological Actions
:
Hepatoprotective
,
Renoprotective
Problem Substances
:
Diclofenac
[+]
Allicin promotes functional recovery in ischemic stroke.
Sep 05, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Death Discov. 2023 Sep 6 ;9(1):335. Epub 2023 Sep 6. PMID:
37673878
Article Published Date
: Sep 05, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Stroke: Ischemic
Pharmacological Actions
:
Glutathione Peroxidase 1 (GPx1) Up-Regulation
,
Neuroprotective Agents
[+]
Allicin protects against myocardial I/R by accelerating angiogenesis via the miR-19a-3p/PI3K/AKT axis.
Oct 03, 2021
Click here to read the entire abstract
Pubmed Data
: Aging (Albany NY). 2021 Oct 4 ;13(undefined). Epub 2021 Oct 4. PMID:
34607973
Article Published Date
: Oct 03, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Angiogenesis Inducing Agents
,
Anti-Inflammatory Agents
,
MicroRNA modulator
[+]
Allicin protects against renal ischemia-reperfusion injury by attenuating oxidative stress and apoptosis.
Nov 24, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int Urol Nephrol. 2021 Nov 25. Epub 2021 Nov 25. PMID:
34825305
Article Published Date
: Nov 24, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Renoprotective
[+]
Allicin protects auditory hair cells and spiral ganglion neurons from cisplatin.
Mar 31, 2017
Click here to read the entire abstract
Pubmed Data
: Neuropharmacology. 2017 Apr ;116:429-440. Epub 2017 Jan 3. PMID:
28062185
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
[+]
Allicin provided cardioprotection for cardiac hypertrophy.
Nov 30, 2018
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2018 Dec 1 ;51:241-254. Epub 2018 Oct 19. PMID:
30466623
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Cardiac Hypertrophy
,
Endothelial Dysfunction
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Allicin provides protection against arsenic trioxide induced liver injury.
Feb 28, 2017
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2017 Mar ;176(1):192-200. Epub 2016 Aug 25. PMID:
27561292
Article Published Date
: Feb 28, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Arsenic Poisoning
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
NF-kappaB Inhibitor
,
Nrf2 activation
Additional Keywords
:
Allicin
,
Antioxidants
,
Arsenic Poisoning
,
NF-kappaB Inhibitor
,
Nrf2 activation
,
oxidative stress
Problem Substances
:
Arsenic Trioxide
[+]
Allicin regulates Treg/Th17 balance in mice with collagen-induced arthritis.
Apr 30, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Sci Nutr. 2021 May ;9(5):2364-2371. Epub 2021 Apr 7. PMID:
34026055
Article Published Date
: Apr 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Arthritis
Pharmacological Actions
:
Immunomodulatory
[+]
Allicin reversed the process of frailty in aging male Fischer 344 rats with osteoporosis.
Sep 20, 2019
Click here to read the entire abstract
Pubmed Data
: J Gerontol A Biol Sci Med Sci. 2019 Sep 21. Epub 2019 Sep 21. PMID:
31541608
Article Published Date
: Sep 20, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Osteoporosis
Pharmacological Actions
:
Osteoprotective
[+]
Allicin showed an antihypertensive, nephroprotective, cardioprotective, and antioxidant effects.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2016 ;2016:3850402. Epub 2016 Nov 21. PMID:
27990229
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Chronic Kidney Disease (CKD)
,
Hypertension
,
Oxidative Stress
Pharmacological Actions
:
Antihypertensive Agents
,
Antioxidants
,
Cardioprotective
,
Renoprotective
[+]
Allicin suppressed Escherichia coli-induced urinary tract infections by a novel MALT1/NF-κB pathway.
Mar 04, 2022
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2022 Mar 5. Epub 2022 Mar 5. PMID:
35246671
Article Published Date
: Mar 04, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Escherichia coli Infections
Pharmacological Actions
:
Anti-Bacterial Agents
[+]
Allicin treatment for 8 weeks partially reverse dexamethasone induced hypertension in rats.
Feb 28, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Integr Med Res. 2017 Mar ;6(1):60-65. Epub 2016 Dec 16. PMID:
28462145
Article Published Date
: Feb 28, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
[+]
Allicin was found to be potentially effective on wound healing.
Jul 01, 2020
Click here to read the entire abstract
Pubmed Data
: J Wound Care. 2020 Jul 2 ;29(7):388-392. PMID:
32654608
Article Published Date
: Jul 01, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Wound Healing
[+]
Allicin, a dietary trpa1 agonist, prevents high fat diet-induced dysregulation of gut hormones and associated complications.
Oct 26, 2021
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2021 Oct 27. Epub 2021 Oct 27. PMID:
34705006
Article Published Date
: Oct 26, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
High Fat Diet
Pharmacological Actions
:
Gastrointestinal Agents
[+]
Allicin‐induced host‐gut microbe interactions improves energy homeostasis.
Jul 02, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: FASEB J. 2020 Jul 3. Epub 2020 Jul 3. PMID:
32619085
Article Published Date
: Jul 02, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Obesity
Pharmacological Actions
:
Gastrointestinal Agents
Additional Keywords
:
Anti-Obesity Agents
[+]
Alliin alleviates myocardial ischemia-reperfusion injury by promoting autophagy.
Apr 29, 2019
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2019 Apr 30 ;512(2):236-243. Epub 2019 Mar 15. PMID:
30885435
Article Published Date
: Apr 29, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Autophagy Up-regulation
,
Cardioprotective
[+]
Alliin alters gut microbiota and gene expression of colonic epithelial tissues.
Mar 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Food Biochem. 2019 Apr ;43(4):e12795. Epub 2019 Feb 21. PMID:
31353605
Article Published Date
: Mar 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Bacterial Infections
Pharmacological Actions
:
Antimicrobial
,
Gastrointestinal Agents
,
Immunomodulatory
Additional Keywords
:
Gene Expression Regulation
,
Microbiota
[+]
Ameliorative effect of allicin on vascular calcification via inhibiting endoplasmic reticulum stress.
Jul 22, 2021
Click here to read the entire abstract
Pubmed Data
: Vascular. 2021 Jul 23:17085381211035291. Epub 2021 Jul 23. PMID:
34301159
Article Published Date
: Jul 22, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Vascular Calcification
Pharmacological Actions
:
Vasoprotective
[+]
Ameliorative role of diallyl disulfide against glycerol-induced nephrotoxicity.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Pharm Bioallied Sci. 2021 Jan-Mar;13(1):129-135. Epub 2020 Dec 21. PMID:
34084059
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
Diseases
:
Kidney Damage: Chemically-Induced
Pharmacological Actions
:
Renoprotective
[+]
Anti-gastric cancer effects of Z Ajoene and its molecular mechanisms.
Aug 31, 2021
Click here to read the entire abstract
Pubmed Data
: Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2021 Sep ;37(5):514-519. PMID:
34816664
Article Published Date
: Aug 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Organosulfur Compounds
Diseases
:
Gastric Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
Anti-inflammatory effect of allicin associated with fibrosis in pulmonary arterial hypertension.
Aug 09, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2021 Aug 10 ;22(16). Epub 2021 Aug 10. PMID:
34445305
Article Published Date
: Aug 09, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Hypertension: Pulmonary
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Transforming growth factor beta (TGF-β) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-inflammatory effect of sulforaphane on LPS-stimulated RAW 264.7 cells and ob/ob mice.
Oct 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Vet Sci. 2020 Nov ;21(6):e91. PMID:
33263238
Article Published Date
: Oct 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-obesity effect of sulforaphane in broccoli leaf extract on 3T3-L1 adipocytes and ob/ob mice.
Jan 31, 2022
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2022 Feb ;100:108885. Epub 2021 Oct 13. PMID:
34655754
Article Published Date
: Jan 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Broccoli
,
Sulforaphane
Diseases
:
Obesity
Pharmacological Actions
:
Hypolipidemic
Additional Keywords
:
Anti-Obesity Agents
[+]
Antioxidant and anti-apoptotic potency of allicin and lycopene against methotrexate-induced cardiac injury.
Jul 31, 2023
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2023 Aug ;30(38):88724-88733. Epub 2023 Jul 13. PMID:
37440131
Article Published Date
: Jul 31, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
,
Lycopene
Diseases
:
Drug Toxicity: Methotrexate
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Cardioprotective
[+]
Antischistosomal and anti-inflammatory activity of garlic and allicin compared with that of praziquantel in vivo.
Apr 26, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2018 Apr 27 ;18(1):135. Epub 2018 Apr 27. PMID:
29703259
Article Published Date
: Apr 26, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
,
Garlic
Diseases
:
Schistosomiasis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Schistosomicides
Additional Keywords
:
Natural Substances Versus Drugs
[+]
Antiviral activity of diallyl trisulfide against H9N2 avian influenza virus infection in vitro and in vivo.
Jan 18, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Virol J. 2021 08 19 ;18(1):171. Epub 2021 Aug 19. PMID:
34412671
Article Published Date
: Jan 18, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Organosulfur Compounds
Diseases
:
Influenza
Pharmacological Actions
:
Antiviral Agents
[+]
Atherosclerosis amelioration by allicin in raw garlic through gut microbiota and trimethylamine-N-oxide modulation.
Jan 26, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: NPJ Biofilms Microbiomes. 2022 Jan 27 ;8(1):4. Epub 2022 Jan 27. PMID:
35087050
Article Published Date
: Jan 26, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Cardiovascular Disease
Pharmacological Actions
:
Cardioprotective
,
Gastrointestinal Agents
[+]
Authors conclude that data from this study provides evidence for the use of sulforaphane in preventing stroke in selected high-risk patient cohorts.
Jan 01, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Pharmacol. 2018 08 ;175(16):3333-3346. Epub 2018 Jul 3. PMID:
29797311
Article Published Date
: Jan 01, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Stroke
Pharmacological Actions
:
Platelet aggregation inhibitor: collagen-induced aggregation
Additional Keywords
:
Broccoli
,
Broccoli Sprouts
,
Cruciferous Vegetables
[+]
Benzyl isothiocyanate and sulforaphane protect against initiation of pancreatic carcinogenesis in hamsters.
Sep 28, 2006
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 2006 Sep 28;241(2):275-80. Epub 2006 Jan 4. PMID:
16386831
Article Published Date
: Sep 28, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Benzyl isothiocyanate
,
Sulforaphane
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Isothiocyanates
,
Stilbenes
[+]
Broccoli and its phytochemical sulforaphane activate detoxification enzymes that may protect against polycyclic aromatic hydrocarbon induced toxicity.
Mar 01, 2009
Click here to read the entire abstract
Pubmed Data
: Chemosphere. 2009 Mar;74(9):1145-51. Epub 2009 Jan 13. PMID:
19144376
Article Published Date
: Mar 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Oxidative Stress
,
Petroleum Exposure And Toxicity
,
Polycyclic aromatic hydrocarbon (PAH) toxicity
Pharmacological Actions
:
Phase II Detoxification Enzyme Inducer
[+]
Broccoli sprout could be prophylactic vegetable to prevent or minimize the relapse by inflammation in the remission state of depressed patients.
Oct 10, 2016
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2016 Oct 11 ;39:134-144. Epub 2016 Aug 11. PMID:
27833054
Article Published Date
: Oct 10, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Broccoli Sprouts
,
Sulforaphane
Diseases
:
Depression
,
Depressive Disorder
,
Inflammation
Pharmacological Actions
:
Antidepressive Agents
Additional Keywords
:
Risk Reduction
[+]
Broccoli sprout extract containing sulforaphane attentuated alcohol-induced oxidative stress and endoplasmic reticulum stress through restoration of antioxidant enzyme function in mice.
Jun 06, 2018
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2018 Jun 6 ;66(22):5574-5580. Epub 2018 May 23. PMID:
29730925
Article Published Date
: Jun 06, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Broccoli Sprouts
,
Sulforaphane
Diseases
:
Alcohol Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Malondialdehyde Down-regulation
,
Nrf2 activation
,
Phase II Detoxification Enzyme Inducer
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Broccoli sprouts can serve as a good dietary source of sulforaphane in vivo and that they have significant inhibitory effects on prostate tumorigenesis.
Oct 01, 2009
Click here to read the entire abstract
Pubmed Data
: Pharm Res. 2009 Oct;26(10):2324-31. Epub 2009 Aug 8. PMID:
19669099
Article Published Date
: Oct 01, 2009
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Broccoli
,
Sprouts
,
Sulforaphane
Diseases
:
Prostate Cancer
,
Prostate Cancer: Prevention
Pharmacological Actions
:
Apoptotic
Additional Keywords
:
Plant Extracts
[+]
Broccoli sprouts contain compounds which protect the skin against damage by UV radiation.
Oct 30, 2007
Click here to read the entire abstract
Pubmed Data
: Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17500-5. Epub 2007 Oct 23. PMID:
17956979
Article Published Date
: Oct 30, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Broccoli
,
Sprouts
,
Sulforaphane
Diseases
:
Aging Skin
[+]
Brocolli sprout extract and the active compound known as sulforaphane demonstrates chemopreventive action in mammary tissue.
Jul 01, 2007
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2007 Jul;28(7):1485-90. Epub 2007 Mar 7. PMID:
17347138
Article Published Date
: Jul 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Broccoli
,
Sulforaphane
Diseases
:
Breast Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Brussel sprouts induce detoxifying enzymes.
Aug 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Food Sci. 2010 Aug 1;75(6):H190-9. PMID:
20722931
Article Published Date
: Aug 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Brussel sprouts
,
Sulforaphane
Diseases
:
Chemical Exposure
,
Intoxication
Pharmacological Actions
:
Phase I Detoxification Enzyme Inducer
,
Phase II Detoxification Enzyme Inducer
Additional Keywords
:
Isothiocyanates
,
Plant Extracts
[+]
Co-administration of SFN reversed the DOX-associated reduction in nuclear Nrf2 binding activity and restored cardiac expression of Nrf2-regulated genes, at both the RNA and protein levels.
May 25, 2015
Click here to read the entire abstract
Pubmed Data
: Free Radic Biol Med. 2015 May 26. Epub 2015 May 26. PMID:
26025579
Article Published Date
: May 25, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
,
Nrf2 activation
[+]
Co-treatment with vitamin E, sulphoraphane and Ficus religiosa were found to be effective in reversing cadmium induced reproductive toxicity.
Jul 31, 2014
Click here to read the entire abstract
Pubmed Data
: Syst Biol Reprod Med. 2014 Aug ;60(4):199-205. Epub 2014 Apr 23. PMID:
24758558
Article Published Date
: Jul 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Fig
,
Sulforaphane
,
Vitamin E
Diseases
:
Cadmium Poisoning
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Cytoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Cadmium
[+]
Combination of two or three components showed striking synergetic effect with gemcitabine in vitro.
Jan 11, 2017
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 2017 Jan 12. Epub 2017 Jan 12. PMID:
28089829
Article Published Date
: Jan 11, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Capsaicin
,
Piceatannol
,
Resveratrol
,
Sulforaphane
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Chemosensitizer
,
Chemotherapeutic
Additional Keywords
:
Chemotherapeutic Synergy: Gemcitabine
,
Natural Substance Synergy
[+]
Consumption of sulforaphane-enriched broccoli soup may inhibit bacterial growth in the stomach and upper small intestine.
Jul 09, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Eur J Nutr. 2020 Jul 10. Epub 2020 Jul 10. PMID:
32651764
Article Published Date
: Jul 09, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Broccoli
,
Sulforaphane
Diseases
:
Escherichia coli Infections
Pharmacological Actions
:
Antimicrobial
[+]
Continuous exposure of pancreatic cancer cells to dietary bioactive agents does not induce drug resistance unlike chemotherapy.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Death Dis. 2016 ;7(6):e2246. Epub 2016 Jun 2. PMID:
27253410
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Quercetin
,
Sulforaphane
Diseases
:
Cancers: Drug Resistant
,
Pancreatic Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
Diallyl disulfide administration prevents and reveres lipopolysaccharide-induced depression-like behaviours.
Jul 31, 2021
Click here to read the entire abstract
Pubmed Data
: Inflammation. 2021 Aug ;44(4):1381-1395. Epub 2021 Jan 29. PMID:
33511484
Article Published Date
: Jul 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
Diseases
:
Brain Inflammation
,
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Antioxidants
[+]
Diallyl disulfide alleviates hypercholesterolemia induced by a western diet.
May 02, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Med Ther. 2023 May 3 ;23(1):141. Epub 2023 May 3. PMID:
37138269
Article Published Date
: May 02, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Organosulfur Compounds
Diseases
:
Hypercholesterolemia
Pharmacological Actions
:
Anticholesteremic Agents
Anti Therapeutic Actions
:
Western Diet
[+]
Diallyl disulfide ameliorates intestinal Candida albicans infection.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Cell Infect Microbiol. 2021 ;11:743454. Epub 2022 Jan 7. PMID:
35071031
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Organosulfur Compounds
Diseases
:
Candida Albicans
Pharmacological Actions
:
Anti-Bacterial Agents
,
Gastrointestinal Agents
,
Gastroprotective
[+]
Diallyl disulfide ameliorates methotrexate-induced nephropathy.
Dec 31, 2020
Click here to read the entire abstract
Pubmed Data
: J Food Biochem. 2021 06 ;45(6):e13765. Epub 2021 May 16. PMID:
33997994
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
Diseases
:
Drug Toxicity: Methotrexate
,
Kidney Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Renoprotective
Problem Substances
:
Methotrexate
[+]
Diallyl disulfide and diallyl trisulfide have the potential to attenuate neuropathic pain.
Jun 30, 2020
Click here to read the entire abstract
Pubmed Data
: Korean J Pain. 2020 Jul 1 ;33(3):216-225. PMID:
32606266
Article Published Date
: Jun 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
Diseases
:
Neuropathic Pain
Pharmacological Actions
:
Antioxidants
,
Nrf2 activation
[+]
Diallyl disulfide attenuates non‑alcoholic steatohepatitis.
Jul 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2019 Aug ;20(2):1363-1372. Epub 2019 May 31. PMID:
31173200
Article Published Date
: Jul 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
Diseases
:
Inflammation
,
Lipid Peroxidation
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
[+]
Diallyl disulfide down-regulates calreticulin and promotes C/EBPα expression in differentiation of human leukaemia cells.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cell Mol Med. 2019 01 ;23(1):194-204. Epub 2018 Nov 5. PMID:
30394654
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
Diseases
:
Leukemia: Acute myelogenous leukemia (AML)
Pharmacological Actions
:
Antiproliferative
[+]
Diallyl disulfide may be a potential therapeutic candidate for the treatment of rheumatoid arthritis.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: J Environ Pathol Toxicol Oncol. 2018 ;37(4):291-303. PMID:
30806236
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Phytotherapy
,
Plant Extracts
Problem Substances
:
Freund adjuvant
[+]
Diallyl disulfide mitigates DNA damage and spleen tissue effects after irradiation.
Nov 23, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Med Sci Monit. 2019 Nov 24 ;25:8920-8927. Epub 2019 Nov 24. PMID:
31760404
Article Published Date
: Nov 23, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
Diseases
:
DNA damage
,
Radiation
Pharmacological Actions
:
Anti-Apoptotic
,
Radioprotective
[+]
Diallyl disulfide prevents 1,3-dichloro-2-propanol-induced hepatotoxicity through mitogen-activated protein kinases signaling.
Jan 05, 2022
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2022 Jan 6 ;160:112814. Epub 2022 Jan 6. PMID:
34999178
Article Published Date
: Jan 05, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Organosulfur Compounds
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Diallyl disulfide prevents cigarette smoke-induced emphysema.
Jul 31, 2021
Click here to read the entire abstract
Pubmed Data
: Pulm Pharmacol Ther. 2021 Aug ;69:102053. Epub 2021 Jul 5. PMID:
34214692
Article Published Date
: Jul 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
Diseases
:
Emphysema: Pulmonary
,
Lung Injury: Smoke-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Enzyme Activators
[+]
Diallyl sulfide protects against dilated cardiomyopathy via inhibition of oxidative stress and apoptosis.
Nov 30, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2021 Dec ;24(6). Epub 2021 Oct 15. PMID:
34651661
Article Published Date
: Nov 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Organosulfur Compounds
Diseases
:
Cardiomyopathy
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Cardioprotective
[+]
Diallyl trisulfide inhibited tobacco smoke-mediated bladder EMT and cancer stem cell marker expression via the NF-κB pathway in vivo.
Feb 28, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Int Med Res. 2021 Mar ;49(3):300060521992900. PMID:
33730908
Article Published Date
: Feb 28, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Organosulfur Compounds
Diseases
:
Bladder Cancer
,
Smoking
Pharmacological Actions
:
NF-kappaB Inhibitor
Additional Keywords
:
Cancer Stem Cells
[+]
Diallyl trisulfide inhibits leptin-induced oncogenic signalling in human breast cancer cells.
Mar 29, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cancer Prev. 2020 Mar 30 ;25(1):1-12. PMID:
32266174
Article Published Date
: Mar 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
Diseases
:
Breast Cancer
Pharmacological Actions
:
Chemopreventive
,
Chemotherapeutic
[+]
Diallyl trisulfide potentiates chemotherapeutic efficacy of doxorubicin in experimentally induced mammary carcinoma.
Jul 26, 2020
Click here to read the entire abstract
Pubmed Data
: Pathol Res Pract. 2020 Jul 27 ;216(10):153139. Epub 2020 Jul 27. PMID:
32853959
Article Published Date
: Jul 26, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Organosulfur Compounds
Diseases
:
Breast Cancer
Pharmacological Actions
:
Antiproliferative
,
Chemosensitizer
Additional Keywords
:
Chemotherapeutic Synergy: Doxorubicin
[+]
Diallyl trisulfide promotes colonic mucosal healing in ulcerative colitis.
Mar 19, 2023
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2023 Mar 20:e2200784. Epub 2023 Mar 20. PMID:
36938915
Article Published Date
: Mar 19, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Gastrointestinal Agents
,
Gastroprotective
[+]
Diallyl trisulfide promotes placental angiogenesis by regulating lipid metabolism and alleviating inflammatory responses in obese pregnant mice.
May 25, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2022 May 26 ;14(11). Epub 2022 May 26. PMID:
35684030
Article Published Date
: May 25, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Organosulfur Compounds
Diseases
:
Inflammation
,
Obesity
,
Pregnancy Complications
Pharmacological Actions
:
Angiogenesis Inducing Agents
,
Anti-Inflammatory Agents
[+]
Diallyl trisulfide protects against concanavalin A-induced acute liver injury.
Jul 31, 2021
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2021 Aug 1 ;278:119631. Epub 2021 May 19. PMID:
34022202
Article Published Date
: Jul 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Organosulfur Compounds
Diseases
:
Inflammation
,
Liver Damage: Drug-Induced
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Concanavalin A
[+]
Diallyl trisulfide regulates cell apoptosis and invasion in human osteosarcoma U2OS cells.
Nov 30, 2020
Click here to read the entire abstract
Pubmed Data
: Histol Histopathol. 2020 Dec ;35(12):1511-1520. Epub 2020 Dec 29. PMID:
33372687
Article Published Date
: Nov 30, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Organosulfur Compounds
Diseases
:
Osteosarcoma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Bcl-2 protein down-regulation
[+]
Diallyl trisulfide suppresses angiotensin II-induced vascular remodelling Via inhibition of mitochondrial fission.
Sep 30, 2020
Click here to read the entire abstract
Pubmed Data
: Cardiovasc Drugs Ther. 2020 Oct ;34(5):605-618. PMID:
32564303
Article Published Date
: Sep 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
Diseases
:
Endothelial Damage
,
Hyperglycemia
[+]
dietary intake of SFN-rich broccoli sprouts during the juvenile and adolescence may prevent the onset of psychosis at adulthood.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(6):e0127244. Epub 2015 Jun 24. PMID:
26107664
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Broccoli Sprouts
,
Sulforaphane
Diseases
:
Cognitive Decline/Dysfunction
,
Neurologic Disorders
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
,
Nrf2 activation
Additional Keywords
:
Plant Extracts
[+]
Dietary supplementation with sulforaphane ameliorates skin aging.
Nov 30, 2021
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2021 Dec ;98:108817. Epub 2021 Jul 14. PMID:
34271100
Article Published Date
: Nov 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Aging Skin
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Nrf2 activation
[+]
Dietary supplementation with sulforaphane attenuates liver damage and heme overload in a sickle cell disease murine model.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Hematol. 2019 09 ;77:51-60.e1. Epub 2019 Aug 9. PMID:
31404577
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Liver Damage
,
Sickle Cell Anemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Nrf2 activation
[+]
Effect of allicin and artesunate combination treatment on experimental mice infected with Plasmodium berghei.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Vet Med Int. 2022 ;2022:7626618. Epub 2022 Apr 18. PMID:
35479191
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
,
Artesunate
Diseases
:
Malaria
Pharmacological Actions
:
Antimalarials
[+]
Effects of diallyl disulfide on the proliferation and apoptosis of epithelial ovarian cancer cells.
Feb 27, 2019
Click here to read the entire abstract
Pubmed Data
: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2019 Feb 28 ;41(1):43-52. PMID:
30837041
Article Published Date
: Feb 27, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
[+]
Garlic powder prevents carcinogen-induced DNA damage in rat liver and colon.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2006 ;55(2):178-84. PMID:
17044773
Article Published Date
: Jan 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
,
Garlic
Diseases
:
Colon Cancer: Prevention
,
DNA damage
,
Liver Cancer: Prevention
Pharmacological Actions
:
Antineoplastic Agents
,
Chemopreventive
[+]
Garlic-derived organosulfur compounds regulate metabolic and immune pathways in macrophages and attenuate intestinal inflammation.
Feb 01, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Nutr Food Res. 2022 Feb 2:e2101004. Epub 2022 Feb 2. PMID:
35107883
Article Published Date
: Feb 01, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Organosulfur Compounds
Diseases
:
Gastrointestinal Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Gene expression changes by diallyl trisulfide administration in chemically-induced mammary tumors.
Mar 29, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cancer Prev. 2022 Mar 30 ;27(1):22-30. PMID:
35419300
Article Published Date
: Mar 29, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Organosulfur Compounds
Diseases
:
Breast Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Gene Expression Regulation
[+]
Glucoraphanin supplementation attenuated weight gain, decreased hepatic steatosis, and improved glucose tolerance and insulin sensitivity.
Feb 15, 2017
Click here to read the entire abstract
Pubmed Data
: Diabetes. 2017 Feb 16. Epub 2017 Feb 16. PMID:
28209760
Article Published Date
: Feb 15, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Insulin Resistance
,
Nonalcoholic fatty liver disease (NAFLD)
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Nrf2 activation
Additional Keywords
:
Anti-Obesity Agents
,
Gene Expression Regulation
[+]
Hepatoprotective effect of allicin against acetaminophen-induced liver injury.
Feb 09, 2020
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2020 Feb 10:e22470. Epub 2020 Feb 10. PMID:
32040233
Article Published Date
: Feb 09, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-1 beta downregulation
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Hepatoprotective effect of diallyl trisulfide against lipopolysaccharide and D-galactosamine induced acute liver failure.
Mar 31, 2022
Click here to read the entire abstract
Pubmed Data
: Toxicol Res (Camb). 2022 Apr ;11(2):263-271. Epub 2022 Feb 19. PMID:
35510232
Article Published Date
: Mar 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Organosulfur Compounds
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Failure: Acute
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
Hepatoprotective effect of methylsulfonylmethane against carbon tetrachloride-induced acute liver injury in rats.
Aug 31, 2013
Click here to read the entire abstract
Pubmed Data
: Arch Pharm Res. 2013 Sep ;36(9):1140-8. Epub 2013 Apr 17. PMID:
23591777
Article Published Date
: Aug 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Apoptotic
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Hydrogen sulfide inhibits inflammatory pain and enhances the analgesic properties of delta opioid receptors.
Dec 10, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2021 Dec 11 ;10(12). Epub 2021 Dec 11. PMID:
34943080
Article Published Date
: Dec 10, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Organosulfur Compounds
Diseases
:
Chronic Pain
,
Inflammation
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
,
Antioxidants
,
Nrf2 activation
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Hypertensive vascular and cardiac remodeling protection by allicin in spontaneous hypertension rats via CaMK Ⅱ/NF-κB pathway.
Oct 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2022 Nov ;155:113802. Epub 2022 Oct 7. PMID:
36271577
Article Published Date
: Oct 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Cardiovascular Diseases
,
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
,
Cardioprotective
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Inhibitory activities of sulfur compounds in garlic essential oil against Alzheimer's disease-related enzymes and their distribution.
Sep 07, 2021
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2021 Sep 8 ;69(35):10163-10173. Epub 2021 Aug 30. PMID:
34459194
Article Published Date
: Sep 07, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
Diseases
:
Alzheimer's Disease
,
Neurodegenerative Diseases
Pharmacological Actions
:
Neuroprotective Agents
[+]
Inhibitory effects of sulforaphane on NLRP3 inflammasome activation.
Jan 11, 2021
Click here to read the entire abstract
Pubmed Data
: Mol Immunol. 2021 12 ;140:175-185. Epub 2021 Oct 28. PMID:
34717147
Article Published Date
: Jan 11, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
Additional Keywords
:
Epigenetic Modification
[+]
Isothiocyanates exhibit anti-myeloma activity.
Aug 01, 2011
Click here to read the entire abstract
Pubmed Data
: Haematologica. 2011 Aug ;96(8):1170-9. Epub 2011 Jun 28. PMID:
21712538
Article Published Date
: Aug 01, 2011
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Isothiocyanate
,
Sulforaphane
Diseases
:
Multiple Myeloma
Pharmacological Actions
:
Apoptotic
[+]
L-cysteine attenuates the mutagenicity of the antiamebic drug diiodohydroxyquinoline in mice.
Apr 01, 1987
Click here to read the entire abstract
Pubmed Data
: Mutat Res. 1987 Apr;187(4):219-22. PMID:
3104778
Article Published Date
: Apr 01, 1987
Study Type
: Animal Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
,
NAC (N-acetyl-L-cysteine)
Diseases
:
Amebiasis
Additional Keywords
:
Drug-Plant-Vitamin Synergies
[+]
Long-term sulforaphane-treatment restores redox homeostasis and prevents cognitive decline.
Sep 30, 2022
Click here to read the entire abstract
Pubmed Data
: Biogerontology. 2022 Oct ;23(5):587-613. Epub 2022 Aug 12. PMID:
35960458
Article Published Date
: Sep 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Brain: Oxidative Stress
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
,
Prophylactic Agents
[+]
Methylsulfonylmethane ameliorates inflammation.
Jan 09, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Poult Sci. 2022 Jan 10 ;101(4):101706. Epub 2022 Jan 10. PMID:
35121233
Article Published Date
: Jan 09, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Inflammation
,
Mycoplasma Infections
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
[+]
Methylsulfonylmethane and tamoxifen synergistically inhibits tumor growth and metastasis in ER-positive breast cancer xenografts.
Jun 18, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Cancer. 2015 Jun 19 ;15:474. Epub 2015 Jun 19. PMID:
26084564
Article Published Date
: Jun 18, 2015
Study Type
: Animal Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
Additional Keywords
:
Synergy with Tamoxifen
[+]
Methylsulfonylmethane increases the alveolar bone density of mandibles in aging female mice.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Physiol. 2021 ;12:708905. Epub 2021 Oct 4. PMID:
34671266
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Osteoprotective
Additional Keywords
:
Bone Regeneration
[+]
Methylsulfonylmethane is effective against gastric mucosal injury.
Sep 14, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2017 Sep 15 ;811:240-248. Epub 2017 Jun 28. PMID:
28666801
Article Published Date
: Sep 14, 2017
Study Type
: Animal Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Gastric Ulcer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Methylsulfonylmethane is effective against obesity-induced metabolic disorders.
Jan 09, 2016
Click here to read the entire abstract
Pubmed Data
: Metabolism. 2016 10 ;65(10):1508-21. Epub 2016 Jul 20. PMID:
27621186
Article Published Date
: Jan 09, 2016
Study Type
: Animal Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Diabetes Mellitus: Type 2
,
Fatty Liver
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Anti-Obesity Agents
[+]
Methylsulfonylmethane pre-treatment could alleviate hepatic injury induced by acetaminophen intoxication.
Jul 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Iran J Basic Med Sci. 2013 Aug ;16(8):896-900. PMID:
24106592
Article Published Date
: Jul 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Acetaminophen (Tylenol) Toxicity
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Methylsulfonylmethane protects against ethanol-induced brain injury.
Feb 20, 2022
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2022 Feb 21 ;106:108638. Epub 2022 Feb 21. PMID:
35203043
Article Published Date
: Feb 20, 2022
Study Type
: Animal Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Alcohol Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Methylsulfonylmethane significantly ameliorated pancreas and lung histopathological changes.
Aug 31, 2018
Click here to read the entire abstract
Pubmed Data
: J Pharm Pharmacol. 2018 Sep ;70(9):1188-1199. Epub 2018 Jul 3. PMID:
29971769
Article Published Date
: Aug 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Pancreatitis
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Methylsulfonylmethane suppresses breast cancer growth by down-regulating STAT3 and STAT5b pathways.
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2012 ;7(4):e33361. Epub 2012 Apr 2. PMID:
22485142
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Breast Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Methylsulfonylmethane suppresses hepatic tumor development through activation of apoptosis.
Feb 26, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Hepatol. 2014 Feb 27 ;6(2):98-106. PMID:
24575169
Article Published Date
: Feb 26, 2014
Study Type
: Animal Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Liver Cancer
Pharmacological Actions
:
Apoptotic
,
Chemopreventive
[+]
MSM has therapeutic value in an animal model of colitis.
Jun 15, 2011
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2011 Jun 15 ;253(3):197-202. Epub 2011 Apr 2. PMID:
21463646
Article Published Date
: Jun 15, 2011
Study Type
: Animal Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
N-acetyl cysteine inhibits arthersclerosis in uremic rabbits.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Am J Respir Crit Care Med. 2008 Jan 1;177(1):56-65. Epub 2007 Oct 4. PMID:
18356775
Article Published Date
: Jan 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
Diseases
:
Arterial Calcification
,
Arterial Plaque
,
Arteriosclerosis
,
Uremia
[+]
N-acetyl cysteine inhibits balloon-induced arterial thickening in a rabbit experimental model
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: Oral Health Prev Dent. 2007;5(4):327-36. PMID:
11341511
Article Published Date
: Jan 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
Diseases
:
Arterial Thickening
,
Intima Media Thickening
[+]
N-acetylcysteine amide has possible protective effects in neonatal asphyxia.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Dis Markers. 2018 ;2018:5046372. Epub 2018 Jan 30. PMID:
29651324
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
Diseases
:
Asphyxia
Pharmacological Actions
:
Antioxidants
[+]
N-acetylcysteine and thymoquinone have renoprotective effects of against the toxicity of fluoride via multiple mechanisms.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2018 ;2018:5614803. Epub 2018 Jun 28. PMID:
30050936
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
,
Thymoquinone
Diseases
:
Fluoride Toxicity
,
Kidney Damage: Chemically-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Glutathione Upregulation
,
Nrf2 activation
,
Renoprotective
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Sodium Fluoride
[+]
N-acetylcysteine inhibits Mancozeb-induced impairments to the normal development of zebrafish embryos.
Apr 13, 2018
Click here to read the entire abstract
Pubmed Data
: Neurotoxicol Teratol. 2018 Apr 14. Epub 2018 Apr 14. PMID:
29665402
Article Published Date
: Apr 13, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
Diseases
:
Pesticide Toxicity
Pharmacological Actions
:
Cytoprotective
Problem Substances
:
Pesticides
[+]
N-acetylcysteine is capable of attenuating lipid metabolism alterations and abnormal body weight gain in the chronic intermittent hypoxia model.
Jul 02, 2018
Click here to read the entire abstract
Pubmed Data
: Med Sci Monit. 2018 Jul 3 ;24:4583-4591. Epub 2018 Jul 3. PMID:
29968701
Article Published Date
: Jul 02, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
Diseases
:
Hypoxia
,
Obesity
Pharmacological Actions
:
Hypolipidemic
Additional Keywords
:
Anti-Obesity Agents
[+]
N-acetylcysteine protected against titanium dioxide's damaging effects.
May 31, 2018
Click here to read the entire abstract
Pubmed Data
: Int J Fertil Steril. 2018 Jun ;12(3):249-256. Epub 2018 Jun 20. PMID:
29935072
Article Published Date
: May 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
Diseases
:
Testicular Injury: Chemical/Metal Induced
Pharmacological Actions
:
Genoprotective
Problem Substances
:
Titanium Nanoparticles
[+]
N-acetylcysteine protects against chorioretinal damage induced by photodynamic therapy.
Apr 17, 2018
Click here to read the entire abstract
Pubmed Data
: Photodiagnosis Photodyn Ther. 2018 Apr 18. Epub 2018 Apr 18. PMID:
29679669
Article Published Date
: Apr 17, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
Diseases
:
Eye Damage
Therapeutic Actions
:
Photodynamic therapy
Pharmacological Actions
:
Photoprotective
[+]
N-acetylcysteine treatment reduces Age-related hearing loss and memory impairment.
Jul 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Aging Dis. 2018 Aug ;9(4):664-673. Epub 2018 Aug 1. PMID:
30090654
Article Published Date
: Jul 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
Diseases
:
Hearing Loss
[+]
NAC improves the antioxidative capacity of the both glands and protects against oxidative damage to the parotid glands of insulin resistance rats.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2018 ;2018:6581970. Epub 2018 Jan 30. PMID:
29636851
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
Diseases
:
Insulin Resistance
Pharmacological Actions
:
Antioxidants
[+]
Natural garlic organosulfur compounds prevent metabolic disorder of lipid and glucose.
May 17, 2022
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2022 May 18 ;70(19):5829-5837. Epub 2022 May 6. PMID:
35522133
Article Published Date
: May 17, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
Diseases
:
Metabolic Diseases
Pharmacological Actions
:
Gastrointestinal Agents
[+]
Obesity may increase susceptibility to chronic pain often due to poor diet.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Eur J Pain. 2018 08 ;22(7):1203-1213. Epub 2018 Mar 2. PMID:
29436058
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
EGCG (Epigallocatechin gallate)
,
Ginseng
,
Resveratrol
,
Sulforaphane
Diseases
:
Chronic Pain
,
Inflammation
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Inflammatory Diet
,
Risk Factors
[+]
Oncogenic c-Myc is a target of sulforaphane to prevent and eliminate the onset of human prostate cancer.
Mar 14, 2016
Click here to read the entire abstract
Pubmed Data
: J Cell Biochem. 2016 Mar 15. Epub 2016 Mar 15. PMID:
26990292
Article Published Date
: Mar 14, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Cancer Stem Cells
[+]
Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice.
Sep 15, 2005
Click here to read the entire abstract
Pubmed Data
: Cancer Res. 2005 Sep 15;65(18):8548-57. PMID:
16166336
Article Published Date
: Sep 15, 2005
Study Type
: Animal Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
,
Phenethyl isothiocyanate
,
Sulforaphane
Diseases
:
Lung Cancer
,
Nicotine/Tobacco Toxicity
,
Smoking
Pharmacological Actions
:
Anticarcinogenic Agents
Additional Keywords
:
Isothiocyanates
[+]
Pre-treatment with sulforaphane or thymoquinone can reduce acetylsalicylic acid-induced gastric ulcers.
Jun 14, 2016
Click here to read the entire abstract
Pubmed Data
: J Surg Res. 2016 Jun 15 ;203(2):348-59. Epub 2016 Mar 24. PMID:
27363643
Article Published Date
: Jun 14, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
,
Thymoquinone
Diseases
:
Gastric Ulcer
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Anti-Ulcer Agents
,
Antioxidants
,
Gastroprotective
[+]
Profile of insulin resistance in adipose tissue of diet induced obese mice in response to anti-obesity treatment.
Apr 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: FASEB J. 2022 May ;36 Suppl 1. PMID:
35559539
Article Published Date
: Apr 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
Additional Keywords
:
Anti-Obesity Agents
[+]
Prostate cancer chemoprevention by sulforaphane in a preclinical mouse model is associated with inhibition of fatty acid metabolism.
Apr 12, 2018
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2018 Apr 13. Epub 2018 Apr 13. PMID:
29668854
Article Published Date
: Apr 12, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Protective effect and mechanism of action of diallyl disulfide against acetaminophen-induced acute hepatotoxicity.
Oct 31, 2017
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2017 Nov ;109(Pt 1):28-37. Epub 2017 Aug 25. PMID:
28847761
Article Published Date
: Oct 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
,
NF-kappaB Inhibitor
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Protective effect of diallyl disulfide against cerulein-induced acute pancreatitis and associated lung injury.
Feb 29, 2020
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2020 Mar ;80:106136. Epub 2020 Jan 25. PMID:
31991372
Article Published Date
: Feb 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
Diseases
:
Lung Cancer
,
Pancreatitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Protective effect of N-acetylcysteine on dizocilpine-induced testicular oxidative stress in mice.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2019 Jan ;109:1988-1993. Epub 2018 Nov 26. PMID:
30551454
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
Diseases
:
Testicular Injury: Chemical/Metal Induced
Pharmacological Actions
:
Antioxidants
[+]
Protective effect of sulforaphane on oxidative stress and mitochondrial dysfunction associated with status epilepticus.
Jan 03, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Neurobiol. 2023 Jan 4. Epub 2023 Jan 4. PMID:
36598650
Article Published Date
: Jan 03, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Epilepsy
,
Mitochondrial Dysfunction
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Nrf2 activation
[+]
Protective effects of diallyl trisulfide (DATS) against doxorubicin-induced inflammation and oxidative stress in the brain.
Jul 30, 2020
Click here to read the entire abstract
Pubmed Data
: Free Radic Biol Med. 2020 Jul 31 ;160:141-148. Epub 2020 Jul 31. PMID:
32745770
Article Published Date
: Jul 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Organosulfur Compounds
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Neuroprotective Agents
[+]
Protective effects of sulforaphane and aerobic exercise on acute alcoholic hepatic injury in mice.
Oct 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Saudi J Biol Sci. 2020 Nov ;27(11):3145-3149. Epub 2020 Jul 14. PMID:
33100876
Article Published Date
: Oct 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane