Patchouli

Name	AC	CK
Inflammation	14	21
Lipopolysaccharide-Induced Toxicity	7	12
Colorectal Cancer	6	11
Adrenaline: Elevated	1	10
Adrenaline: Low	1	10
Catecholamines: Elevated	1	10
Catecholamines: Low	1	10
Colitis	5	10
Fatigue	1	10
Hypertension	1	10
Stress	1	10
Sympathetic Nervous System Diseases	1	10
Gastric Ulcer	5	8
Helicobacter Pylori Infection	7	8
Nonalcoholic fatty liver disease (NAFLD)	4	8
Alzheimer's Disease	4	7
Obesity	4	7
Chemotherapy-Induced Toxicity: 5-fluorouracil	3	6
Depression	3	6
Irritable Bowel Syndrome	3	6
Oxidative Stress	4	6
Alcohol Toxicity	3	5
Lung Injury: Acute	3	5
Ultraviolet Radiation Induced Damage	3	5
Aging Skin	3	4
Diarrhea: IBS associated	2	4
Drug-Induced Toxicity: Indomethacin	2	4
High Fat Diet	2	4
Inflammatory Bowel Diseases	2	4
Influenza	4	4
Liver Cancer	3	4
Lung Cancer	3	4
Mucositis	2	4
Neurodegenerative Diseases	2	3
Allergies	1	2
Bowel Surgery	1	2
Brain Inflammation	1	2
Brain Ischemia	1	2
Breast Cancer: Bone Metastasis	1	2
Cerebral Ischemia	1	2
Colon Surgery	1	2
Diarrhea	1	2
Endometrial Cancer	1	2
Gastritis	1	2
Gastrointestinal Diseases	1	2
Gram-Negative Bacterial Infections	1	2
Gram-Positive Bacterial Infections	1	2
Hepatic Steatosis	1	2
Hyperalgesia	1	2
Hyperglycemia	1	2
Liver Damage	1	2
Liver Injury: Ischemia/reperfusion	1	2
Mastitis	1	2
Myocardial Ischemia	1	2
Osteoarthritis	1	2
Prostate Cancer	2	2
Short Bowel Syndrome	1	2
Staphylococcus aureus: Methicillin-resistant (MRSA)	1	2
Ulcerative Colitis	1	2
Wound Healing	1	2
Acute Myeloid Leukemia	1	1
Animal Diseases: Porcine Epidemic Diarrhea Virus (PEDV)	1	1
Atherosclerosis	1	1
Bacillus subtilis infections	1	1
Brain Damage	1	1
Brain Diseases	1	1
Brain: Oxidative Stress	1	1
Candida Albicans	1	1
Candida Infection	1	1
Carcinoma: Non-Small-Cell Lung	1	1
Cervical Cancer	1	1
Coronavirus Infection	1	1
Enterobacteriaceae Infections	1	1
Escherichia coli Infections	1	1
Gastroenteritis	1	1
Hypoxia	1	1
Infection: Antibiotic Resistant	1	1
Influenza A	1	1
Lung Damage	1	1
Malignant Melanoma	1	1
Melanoma	1	1
Norovirus	1	1
Osteoporosis	1	1
Ovarian Cancer	1	1
Spinal Cord Injuries	1	1
Staphylococcus aureus infection	1	1
Chagas Disease	1	0
Nausea	1	0

Name	AC	CK
Anti-Inflammatory Agents	37	61
Tumor Necrosis Factor (TNF) Alpha Inhibitor	22	36
Interleukin-6 Downregulation	17	27
Antioxidants	14	22
Interleukin-1 beta downregulation	13	21
NF-kappaB Inhibitor	15	21
Apoptotic	12	19
Antiproliferative	13	17
Gastroprotective	9	17
Neuroprotective Agents	9	15
Gastrointestinal Agents	6	11
Hepatoprotective	5	10
Anti-Ulcer Agents	5	9
Anti-Apoptotic	6	8
Anti-Bacterial Agents	7	8
Antiviral Agents	7	7
Cyclooxygenase 2 Inhibitors	4	7
Antidepressive Agents	3	6
Chemoprotective Agents	3	6
Malondialdehyde Down-regulation	5	6
Antineoplastic Agents	3	5
Nitric Oxide Inhibitor	3	5
Nrf2 activation	3	5
Photoprotective	3	5
Antidiarrheals	2	4
Hypolipidemic	2	4
Interferon Gamma Reducer	2	4
Interleukin-10 upregulation	3	4
Interleukin-17 downregulation	2	4
Anti-metastatic	2	3
Autophagy Up-regulation	1	3
Cardioprotective	2	3
Analgesics	1	2
Anti-Adipogenic	1	2
Anti-Allergic Agents	1	2
Anticholesteremic Agents	1	2
Antihypertensive Agents	1	2
Antinoceceptive	1	2
Autophagy Inhibitors	1	2
Chemopreventive	1	2
Chemotherapeutic	1	2
Enzyme Inhibitors	2	2
Heme oxygenase-1 up-regulation	1	2
Hypoglycemic Agents	1	2
Immunomodulatory	1	2
Immunosuppressive Agents	1	2
Interleukin-18 down-regulation	1	2
MicroRNA modulator	1	2
Prostaglandin PGE2 downregulation	1	2
Antifungal Agents	1	1
Bax/Bcl2 ratio: Increase	1	1
Cell cycle arrest	1	1
Chemosensitizer	1	1
Histone deacetylase inhibitor	1	1
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	1	1
Interleukin-4 downregulation	1	1
Interleukin-4 upregulation	1	1
Interleukin-8 downregulation	1	1
Matrix Metalloproteinase-7 (MMP-7) Inhibitor	1	1
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	1
Matrix metalloproteinase-9 (MMP-9) inhibitor	1	1
Osteoprotective	1	1
P21 Activation	1	1
Postaglandin PGE2 downregulation	1	1
Vascular Endothelial Growth Factor Inhibitors	1	1
Xanthine oxidase inhibitor	1	1

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Fragrance inhalation of patchouli and rose oil reduce sympathetic nervous system activity by 40%; rose oil reduces adrenaline concentrations by 30%. Nov 01, 2002

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Pubmed Data : Jpn J Pharmacol. 2002 Nov;90(3):247-53. PMID: 12499579

Article Published Date : Nov 01, 2002

Study Type : Human Study

Additional Links

Substances : Black Pepper, Patchouli, Rose

Diseases : Adrenaline: Elevated, Adrenaline: Low, Catecholamines: Elevated, Catecholamines: Low, Hypertension, Sympathetic Nervous System Diseases

Therapeutic Actions : Aromatherapy

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Inhalation of patchouli oil effectively reduced the levels of stress and increased compassion satisfaction in emergency nurses.Oct 31, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Med. 2016 Jan ;37(1):217-24. Epub 2015 Nov 3. PMID: 26531835

Pubmed Data : Chin J Integr Med. 2021 Feb ;27(2):125-130. Epub 2016 Apr 13. PMID: 27080999

Article Published Date : Jan 31, 2021

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Patchouli

Diseases : Gram-Negative Bacterial Infections, Gram-Positive Bacterial Infections, Staphylococcus aureus: Methicillin-resistant (MRSA)

Pharmacological Actions : Anti-Bacterial Agents

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Induction of apoptosis in endometrial cancer cells by pogostemon cablin aqueous extract.Jun 01, 2015

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Pubmed Data : Int J Mol Sci. 2015 Jun 2 ;16(6):12424-35. Epub 2015 Jun 2. PMID: 26042464

Article Published Date : Jun 01, 2015

Study Type : Animal Study

Additional Links

Substances : Patchouli

Diseases : Endometrial Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic

Additional Keywords : Plant Extracts

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Inhibitory effects of patchouli alcohol on stress-induced diarrhea-predominant irritable bowel syndrome.Feb 13, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : World J Gastroenterol. 2018 Feb 14 ;24(6):693-705. PMID: 29456408

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Pharmacother. 2020 Apr ;124:109883. Epub 2020 Jan 28. PMID: 32004938

Article Published Date : Mar 31, 2020

Study Type : Animal Study

Additional Links

Substances : Patchouli

Diseases : Chemotherapy-Induced Toxicity: 5-fluorouracil , Mucositis

Pharmacological Actions : Anti-Inflammatory Agents, Chemoprotective Agents, Gastroprotective, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Microbiota

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Patchouli alcohol attenuates the cognitive deficits in a transgenic mouse model of Alzheimer's disease.Jan 29, 2023

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Pubmed Data : Planta Med. 2020 Mar ;86(4):255-266. Epub 2020 Jan 23. PMID: 31975362

Article Published Date : Feb 29, 2020

Study Type : Animal Study

Additional Links

Substances : Patchouli

Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

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Patchouli oil was capable of maintaining skin structural integrity caused by UV irradiation and it was useful in preventing photoaging.Jun 10, 2014

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2017 Feb ;42(3):562-566. PMID: 28952265

Article Published Date : Jan 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Patchouli

Diseases : Helicobacter Pylori Infection

Pharmacological Actions : Anti-Bacterial Agents

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Patchoulene epoxide isolated from patchouli oil suppresses acute inflammation.Dec 31, 2016

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Pubmed Data : Phytother Res. 2015 Jan ;29(1):67-72. Epub 2014 Sep 22. PMID: 25243578

Article Published Date : Dec 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Patchouli

Diseases : Helicobacter Pylori Infection

Pharmacological Actions : Anti-Bacterial Agents

Additional Keywords : Drug: Amoxicillin, Microbiota, Selective Cytotoxicity, Superiority of Natural Substances versus Drugs

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Patchouli alcohol induces G0 /G1 cell cycle arrest and apoptosis in vincristine-resistant non-small cell lung cancer.Jun 30, 2023

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Pubmed Data : Food Funct. 2022 Nov 14 ;13(22):11853-11864. Epub 2022 Nov 14. PMID: 36314728

Article Published Date : Nov 13, 2022

Study Type : In Vitro Study

Additional Links

Substances : Patchouli

Diseases : Inflammation, Obesity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Pogostone attenuates TNF-α-induced injury in A549 cells via inhibiting NF-κB and activating Nrf2 pathways.Aug 31, 2018

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Pubmed Data : Int Immunopharmacol. 2018 Sep ;62:15-22. Epub 2018 Jun 30. PMID: 29966943

Article Published Date : Aug 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Patchouli

Diseases : Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Essential Oils

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Pogostone enhances the antibacterial activity of colistin.Apr 27, 2022

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Pubmed Data : Molecules. 2022 Apr 28 ;27(9). Epub 2022 Apr 28. PMID: 35566163

Article Published Date : Apr 27, 2022

Study Type : In Vitro Study

Additional Links

Substances : Patchouli

Diseases : Enterobacteriaceae Infections, Escherichia coli Infections

Pharmacological Actions : Anti-Bacterial Agents

Additional Keywords : Natural Substance/Drug Synergy

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Problem Substances : Indomethacin

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The results showed that patchouli alcohol significantly inhibited different influenza virus strain multiplication in vitro.Jan 22, 2019

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Pubmed Data : Virol J. 2019 12 23 ;16(1):163. Epub 2019 Dec 23. PMID: 31870450

Article Published Date : Jan 22, 2019

Study Type : In Vitro Study

Additional Links

Substances : Patchouli

Diseases : Influenza

Pharmacological Actions : Antiviral Agents

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These findings suggest that Patchouli alcohol could be a promising membrane fusion inhibitor for the treatment of influenza A infection.Dec 31, 2021

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View the Evidence: 106 Abstracts with Patchouli Research

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Fragrance inhalation of patchouli and rose oil reduce sympathetic nervous system activity by 40%; rose oil reduces adrenaline concentrations by 30%. Nov 01, 2002

Inhalation of patchouli oil effectively reduced the levels of stress and increased compassion satisfaction in emergency nurses.Oct 31, 2020

Pogostone showed anti-colorectal tumor effects by inducing autophagy and apoptosis.Apr 17, 2017

Preventive activity of patchouli alcohol against colorectal cancer and diabetes Mar 31, 2023

Anti-allergic and anti-inflammatory effects of aqueous extract of Pogostemon cablin.Dec 31, 2015

Anti-inflammatory activity of patchouli alcohol isolated from Pogostemonis Herba in animal models.Nov 30, 2011

Anti-nociceptive effect of patchouli alcohol.May 31, 2019

Antidepressant-like activity of patchouli oil.May 14, 2022

Beta-patchoulene protects against non-alcoholic steatohepatitis.Aug 31, 2021

Effect of patchouli essential oil on in vitro and in vivo leukocytes behavior in acute inflammatory response.Nov 30, 2016

Effect of β-patchoulene on cerebral ischemia-reperfusion injury and the TLR4/NF-κB signaling pathway.Apr 30, 2019

Effects of topical application of patchouli alcohol on the UV-induced skin photoaging in mice.Oct 14, 2014

Extract of Pogostemon cablin possesses potent anticancer activity against colorectal cancer cells.Dec 31, 2019

In vitro and in vivo antibacterial activity of patchouli alcohol from Pogostemon cablin.Jan 31, 2021

Induction of apoptosis in endometrial cancer cells by pogostemon cablin aqueous extract.Jun 01, 2015

Inhibitory effects of patchouli alcohol on stress-induced diarrhea-predominant irritable bowel syndrome.Feb 13, 2018

Omeprazole and patchouli alcohol significantly normalizes oxidative stress and inflammatory responses against gastric ulcer.Jul 31, 2020

Oral administration with patchouli alcohol significantly reduced the ulcer areas induced by ethanol, indomethacin and water immersion restraint.Aug 25, 2014

Patchouli alcohol ameliorates acute liver injury via inhibiting oxidative stress and gut-origin LPS leakage.Aug 31, 2021

Patchouli alcohol ameliorates depression-like behaviors.Mar 31, 2023

Patchouli alcohol ameliorates dextran sodium sulfate-induced experimental colitis and suppresses tryptophan catabolism.Jun 30, 2017

Patchouli alcohol ameliorates skeletal muscle insulin resistance and NAFLD.Nov 30, 2021

Patchouli alcohol ameliorates the learning and memory impairments.Oct 31, 2022

Patchouli alcohol as a selective estrogen receptor β agonist ameliorates AD-like pathology.Aug 31, 2022

Patchouli alcohol attenuates 5-fluorouracil-induced intestinal mucositis.Mar 31, 2020

Patchouli alcohol attenuates the cognitive deficits in a transgenic mouse model of Alzheimer's disease.Jan 29, 2023

Patchouli alcohol dampens lipopolysaccharide induced mastitis in mice.Sep 30, 2014

Patchouli alcohol has anti-inflammatory effects of lipopolysaccharide induced acute lung injury in mice. Mar 31, 2015

Patchouli alcohol has the potential to be a promising candidate for treatment of H. pylori-related diseases.Dec 31, 2017

Patchouli alcohol improved diarrhea-predominant irritable bowel syndrome.Dec 31, 2021

Patchouli alcohol improves wound healing in high fat diet-fed mice through AMPK-mediated suppression of inflammation and TGFb1 signalingJan 04, 2021

Patchouli alcohol might be able to serve as a novel antitumor compound in the clinical treatment of lung cancer.Dec 31, 2015

Patchouli alcohol possesses health benefit effect through inhibiting adipogenesis and fat tissue development.Feb 29, 2020

Patchouli alcohol protects against ischemia/reperfusion-induced brain injury.Dec 31, 2017

Patchouli alcohol protects against myocardial ischaemia-reperfusion injury by regulating the Notch1/Hes1 pathway.Nov 30, 2022

Patchouli alcohol: a natural sesquiterpene against both inflammation and intestinal barrier damage of ulcerative colitis. Jul 31, 2020

Patchouli may provide gastrointestinal protection against trauma or surgical operation. Jul 01, 2009

Patchouli oil ameliorates 5-fluorouracil-induced intestinal mucositis.Mar 24, 2020

Patchouli oil ameliorates acute colitis.Jul 31, 2017

Patchouli oil attenuates high fat diet-induced non-alcoholic hepatic steatosis.Feb 29, 2020

Patchouli oil was capable of maintaining skin structural integrity caused by UV irradiation and it was useful in preventing photoaging.Jun 10, 2014

Pogostemon cablin triggered ROS-induced DNA damage to arrest cell cycle progression and induce apoptosis on human hepatocellular carcinoma.Nov 29, 2020

Pogostone attenuates osteolysis in breast cancer.Aug 31, 2023

Protective effect of patchouli alcohol against high-fat diet Induced hepatic steatosis.Dec 31, 2018

Protective effect of the combination of essential oil from patchouli and tangerine peel against gastric ulcer,Jan 09, 2022

Protective effects of patchouli alcohol isolated from Pogostemon cablin on lipopolysaccharide-induced acute lung injury in mice.Jan 31, 2016

Protective effects of Pogostemon cablin Bentham water extract on inflammatory cytokine expression in TNBS-induced colitis in rats.Jan 31, 2014

Protective role of β-patchoulene from Pogostemon cablin against indomethacin-induced gastric ulcer.Jan 14, 2018

T cell inhibition by pogostone from Pogostemon cablin (Blanco) Benth: In vitro and in vivo immunosuppressive analysis.Sep 30, 2017

The effects of patchouli alcohol on diarrhea-predominant irritable bowel syndrome are correlated with phenotypic plasticity in myenteric neurons.Dec 31, 2021

The results render patchouli alcohol a promising antidepressant.Jun 30, 2020

These results demonstrated that patchouli alcohol was a promising candidate for preventing the quality loss of aging cartilage.Dec 31, 2021

These results highlighted the potential of pogostone as a promising candidate to relieve Inflammatory bowel disease.Dec 31, 2016

This data demonstrate that the inhalation of patchouli essential oil influenced certain markers related to metabolic diseases.Jul 12, 2020

Traditional Patchouli essential oil modulates the host's immune responses and gut microbiota and exhibits potent anti-cancer effects.Dec 31, 2021

β-patchoulene ameliorates water transport and the mucus barrier in 5-fluorouracil-induced intestinal mucositis.Dec 31, 2020

β-Patchoulene from patchouli oil protects against LPS-induced acute lung injury.Aug 31, 2017

β-patchoulene improves lipid metabolism to alleviate non-alcoholic fatty liver disease.Jan 31, 2021

β-patchoulene isolated from patchouli oil had Anti-inflammatory activity.Apr 13, 2016

β-Patchoulene preconditioning protects mice against hepatic ischemia-reperfusion injury.Dec 31, 2021

β-patchoulene simultaneously ameliorated dextran sulfate sodium-induced colitis and secondary liver injury.Jan 11, 2020

A new antibacterial octaketide and cytotoxic phenylethanoid glycosides from Pogostemon cablin (Blanco) Benth.Jul 14, 2015

Anti-inflammatory property of the ethanol extract of the root and rhizome of Pogostemon cablin.Dec 31, 2012

Antiviral activity against porcine epidemic diarrhea virus of Pogostemon cablin polysaccharide.Sep 14, 2020

Chemical constituents with antiproliferative activity From Pogostemon cablin.Dec 31, 2021

Effect of patchouli alcohol on Helicobacter pylori-induced neutrophil recruitment and activation.Feb 28, 2019

Effect of patchouli alcohol on macrophage mediated Helicobacter pylori digestion based on intracellular urease inhibition.Nov 30, 2019

Effects of patchouli and cinnamon essential oils on biofilm and hyphae formation by Candida species.May 31, 2018

Effects of Pogostemon cablin extract on hypoxia induced rabbit cardiomyocyte injury.Mar 31, 2015

Evaluation of the pogostone effects on the expression of PTEN and DACT1 tumor suppressor genes, cell cycle, and apoptosis in ovarian cancer.Mar 31, 2022

Immunologic mechanism of Patchouli alcohol anti-H1N1 influenza virus may through regulation of the RLH signal pathway in vitro.Sep 30, 2013

Inhibitory effect and possible mechanism of action of patchouli alcohol against influenza A (H2N2) virus.Aug 02, 2011

Patchouli

View the Evidence:
106 Abstracts with Patchouli Research