Perilla

Views 540
Jump to
Abstracts Focused Research Topics
Download the GMI DOC on this Topic

Focus Your Research

Click any topic below to filter + focus research
50 Diseases Researched for Perilla
NameACCKFocus
Cardiovascular Diseases211Locked
Dyspepsia110Locked
Hypertension110Locked
Aging Skin24Locked
Allergic Rhinitis24Locked
Asthma24Locked
Cancers: All34Locked
Diabetes Mellitus: Type 224Locked
Insomnia24Locked
Obesity24Locked
Ultraviolet Radiation Induced Damage24Locked
Alzheimer's Disease23Locked
Breast Cancer23Locked
Depression23Locked
Inflammation33Locked
Allergic Rhinoconjunctivitis12Locked
Atopic Dermatitis12Locked
Brain: Oxidative Stress22Locked
Cognitive Decline/Dysfunction12Locked
Colitis12Locked
Diabetic Nephropathy12Locked
Dioxin Toxicity 12Locked
Dyslipidemias12Locked
Furan Toxicity 12Locked
Gastric Ulcer12Locked
Hair Loss12Locked
Helicobacter Pylori Infection12Locked
High Fat Diet12Locked
Hydrogen Peroxide Induced Toxicity22Locked
Hypersensitivity: Immediate12Locked
Ileitis12Locked
Inflammatory Bowel Diseases12Locked
Kidney Fibrosis12Locked
Lipopolysaccharide-Induced Toxicity22Locked
Liver Cancer12Locked
Lung Cancer22Locked
Oxidative Stress22Locked
Photooxidative Stress12Locked
Allergies11Locked
Central Nervous System Diseases11Locked
Cough11Locked
Fungal Infection11Locked
Gram-Negative Bacterial Infections11Locked
HIV Infections11Locked
Hepatoma11Locked
Hyperuricemia11Locked
Leukemia11Locked
Neurodegenerative Diseases11Locked
Pseudomonas aeruginosa11Locked
Trichophytosis11Locked
42 Pharmacological Actions Researched for Perilla
NameACCKFocus
Anti-Inflammatory Agents1220Locked
Antihypertensive Agents110Locked
Cardioprotective110Locked
Gastrointestinal Agents110Locked
Neuroprotective Agents57Locked
Antioxidants56Locked
Antiproliferative 56Locked
Anti-Allergic Agents35Locked
Cyclooxygenase 2 Inhibitors35Locked
Interleukin-6 Downregulation35Locked
Apoptotic44Locked
Hypnotics and Sedatives24Locked
Interleukin-1 beta downregulation24Locked
NF-kappaB Inhibitor24Locked
Photoprotective24Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor34Locked
Anti-Bacterial Agents23Locked
Antidepressive Agents23Locked
Cell cycle arrest33Locked
Malondialdehyde Down-regulation23Locked
Acetylcholinesterase Inhibitor12Locked
Alpha-glucosidase inhibitor 12Locked
Anti-Apoptotic12Locked
Anti-Fibrotic12Locked
Gastroprotective12Locked
Glucagon Like peptide 1 (GLP-1) Up-regulation12Locked
Hypoglycemic Agents12Locked
Hypolipidemic12Locked
Immunomodulatory12Locked
Interleukin-6 upregulation12Locked
Interleukin-8 downregulation12Locked
Leukotriene Antagonists12Locked
Nitric Oxide Inhibitor12Locked
Renoprotective12Locked
STAT3 Inhibitor12Locked
Tyrosinase inhibitors12Locked
Antifungal Agents11Locked
Antimicrobial11Locked
Brain-derived neurotrophic factor modulator11Locked
Reverse Transcriptase Inhibitors11Locked
Tumor Suppressor Protein p53 Upregulation11Locked
Xanthine oxidase inhibitor11Locked

View the Evidence:
69 Abstracts with Perilla Research

[+]

Effectiveness of a nutraceutical supplement containing highly standardized perilla and ginger extracts in patients with functional dyspepsia.Feb 29, 2020

Pubmed Data : Minerva Gastroenterol Dietol. 2020 Mar ;66(1):35-40. PMID: 32283883
Article Published Date : Feb 29, 2020
Study Type : Human Study
Additional Links
Substances : Ginger, Perilla
Diseases : Dyspepsia
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Plant Extracts
[+]

Perilla frutescens leaf powder intake may be an effective intervention to prevent cardiovascular diseases.Apr 29, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Apr 30 ;25(9). Epub 2020 Apr 30. PMID: 32365849
Article Published Date : Apr 29, 2020
Study Type : Human Study
Additional Links
Substances : Alpha Linolenic Acid, Perilla
Diseases : Cardiovascular Diseases, Hypertension
Pharmacological Actions : Antihypertensive Agents, Cardioprotective
[+]

Perilla oil intake may improve gut function and microbiota in athletes.Jun 15, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Nutr. 2022 Jun 16:1-36. Epub 2022 Jun 16. PMID: 35705194
Article Published Date : Jun 15, 2022
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids, Perilla
Diseases : Athletic Performance
Pharmacological Actions : Gastrointestinal Agents
[+]

Perilla seed oil enhances cognitive function and mental health in healthy elderly Japanese individuals by enhancing the biological antioxidant potential.May 18, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2021 May 19 ;10(5). Epub 2021 May 19. PMID: 34069601
Article Published Date : May 18, 2021
Study Type : Human Study
Additional Links
Substances : Perilla
Diseases : Aging: Brain , Cognitive Decline/Dysfunction
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Perilla seed oil in combination with nobiletin-rich ponkan powder enhances cognitive function in healthy elderly Japanese individuals.Feb 15, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Funct. 2022 Feb 16. Epub 2022 Feb 16. PMID: 35171190
Article Published Date : Feb 15, 2022
Study Type : Human Study
Additional Links
Substances : Nobiletin , Perilla
Diseases : Aging: Brain , Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

A diet containing P. frutescens extract effectively reversed learning and memory impairment induced by trimethyltin chloride.Oct 26, 2015

Pubmed Data : J Med Food. 2015 Oct 27. Epub 2015 Oct 27. PMID: 26505950
Article Published Date : Oct 26, 2015
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

A flavanone derivative Perilla frutescens potently suppresses IgE-mediated immediate hypersensitivity reactions.Jan 28, 2017

Pubmed Data : Biochem Biophys Res Commun. 2017 01 29 ;483(1):674-679. Epub 2016 Dec 13. PMID: 27986566
Article Published Date : Jan 28, 2017
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Allergic Rhinitis, Hypersensitivity: Immediate
Pharmacological Actions : Anti-Allergic Agents
[+]

A variety of vegetables reduce the absorption and enhance excretion of dioxin and furan toxins. May 01, 1999

Pubmed Data : Fukuoka Igaku Zasshi. 1999 May;90(5):171-83. PMID: 10396873
Article Published Date : May 01, 1999
Study Type : Animal Study
Additional Links
Substances : Broccoli, Cabbage, Chives, Kale, Onion, Perilla , Spinach, Vegetables: All
Diseases : Dioxin Toxicity , Furan Toxicity
[+]

Anti-Helicobacter pylori activity of acomplex mixture of Lactobacillus paracasei HP7 including the extract of Perilla frutescens var. acuta and Glycyrrhiza glabra.Oct 27, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lab Anim Res. 2020 Oct 28 ;36(1):40. Epub 2020 Oct 28. PMID: 33292858
Article Published Date : Oct 27, 2020
Study Type : Animal Study
Additional Links
Substances : Lactobacillus paracasei, Licorice, Perilla
Diseases : Helicobacter Pylori Infection
Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents, Interleukin-8 downregulation
[+]

Anti-inflammatory effect of Perilla frutescens seed oil rich in omega-3 fatty acid on dextran sodium sulfate-induced colitis in mice.Sep 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Res Pharm Sci. 2021 Oct ;16(5):464-473. Epub 2021 Aug 19. PMID: 34522194
Article Published Date : Sep 30, 2021
Study Type : Animal Study
Additional Links
Substances : Omega-3 Fatty Acids, Perilla
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Cold-pressed perilla oil has therapeutic potential in terms of protecting against skin photo-aging.Feb 21, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Feb 22 ;25(4). Epub 2020 Feb 22. PMID: 32098445
Article Published Date : Feb 21, 2020
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Aging Skin, Photooxidative Stress, Ultraviolet Radiation Induced Damage
Pharmacological Actions : Photoprotective
Additional Keywords : Plant Oils
[+]

Effects of Perilla frutescens var. acuta in amyloid β toxicity and Alzheimer's disease-like pathology in 5XFAD mice.Feb 28, 2022

Pubmed Data : Food Chem Toxicol. 2022 Mar ;161:112847. Epub 2022 Feb 7. PMID: 35143918
Article Published Date : Feb 28, 2022
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Essential oil of P. frutescens administration exhibited significant antidepressant-like effects in mice with CUMS-induced depression.Sep 30, 2014

Pubmed Data : Chin J Nat Med. 2014 Oct ;12(10):753-9. Epub 2014 Oct 31. PMID: 25443368
Article Published Date : Sep 30, 2014
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents
Additional Keywords : Essential Oils
[+]

Omega-3 fatty acids (fish and perilla oil) are beneficial for small intestine inflammation associated with ileitis. Dec 01, 2009

Pubmed Data : Clin Exp Immunol. 2009 Dec;158(3):325-33. Epub 2009 Sep 30. PMID: 19793338
Article Published Date : Dec 01, 2009
Study Type : Animal Study
Additional Links
Substances : Fish Oil, Omega-3 Fatty Acids, Perilla
Diseases : Ileitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 upregulation
[+]

P. frutescens leaf exhibits excellent hypoglycemic activity in vitro and in vivo.Feb 02, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2021 Feb 3 ;10(2). Epub 2021 Feb 3. PMID: 33546380
Article Published Date : Feb 02, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Perilla
Diseases : Breast Cancer, Cancers: All, Diabetes Mellitus: Type 2, Liver Cancer
Pharmacological Actions : Acetylcholinesterase Inhibitor, Alpha-glucosidase inhibitor , Antiproliferative , Tyrosinase inhibitors
[+]

Perilla fruit water extract can be a potential drug to assist the treatment of airway respiratory distress syndrome.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:4444513. Epub 2022 Jun 30. PMID: 35815275
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Acute Respiratory Distress Syndrome, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Interleukin-8 downregulation
[+]

Perilla frutescens and its active compound rosmarinic acid have beneficial effects on cognitive improvement and may help prevent Alzheimer's disease.May 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res Pract. 2016 Jun ;10(3):274-81. Epub 2016 Apr 1. PMID: 27247723
Article Published Date : May 31, 2016
Study Type : Animal Study
Additional Links
Substances : Perilla , Rosmarinic acid
Diseases : Alzheimer's Disease
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor
[+]

Perilla frutescens and rosmarinic acid may play a role in ameliorating allergy diseases.Jan 01, 2011

Pubmed Data : Exp Biol Med (Maywood). 2011 Jan;236(1):99-106. PMID: 21239739
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Perilla , Rosmarinic acid
Diseases : Allergic Rhinitis, Allergic Rhinoconjunctivitis
Pharmacological Actions : Anti-Allergic Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor
Additional Keywords : Plant Extracts
[+]

Perilla frutescens extracts protects against dextran sulfate sodium-induced murine colitis.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2017 ;8:482. Epub 2017 Aug 8. PMID: 28848431
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, STAT3 Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Perilla frutescens leaf could be a potential therapeutic agent and food supplement for NSAID-induced gastric injuries.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2019 ;2019:9514703. Epub 2019 Mar 4. PMID: 30949513
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Perilla , Rosemaric Acid
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Gastroprotective
Problem Substances : Indomethacin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Perilla frutescens leaves attenuate dextran sulfate sodium-induced acute colitis.Dec 31, 2019

Pubmed Data : Food Sci Biotechnol. 2020 Jan ;29(1):131-140. Epub 2019 Nov 25. PMID: 31976135
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Perilla frutescens leaves extract ameliorates ultraviolet radiation-induced extracellular matrix damage.Jan 03, 2017

Pubmed Data : J Ethnopharmacol. 2017 Jan 4 ;195:334-342. Epub 2016 Nov 22. PMID: 27888134
Article Published Date : Jan 03, 2017
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Aging Skin, Ultraviolet Radiation Induced Damage
Pharmacological Actions : Photoprotective
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Perilla frutescens sprout displays beneficial effects in the prevention and treatment of type 2 diabetes.Jan 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res Pract. 2018 Feb ;12(1):20-28. Epub 2018 Jan 12. PMID: 29399293
Article Published Date : Jan 31, 2018
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
[+]

Perilla frutescens sprout extract may be useful for the prevention or treatment of diabetic nephropathy.Feb 07, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Feb 8 ;11(2). Epub 2019 Feb 8. PMID: 30744045
Article Published Date : Feb 07, 2019
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Diabetic Nephropathy, Kidney Fibrosis
Pharmacological Actions : Anti-Fibrotic, Renoprotective
[+]

Perilla increases glucagon-like peptide secretion.May 01, 2008

Pubmed Data : Biol Pharm Bull. 2008 May;31(5):1021-3. PMID: 18451539
Article Published Date : May 01, 2008
Study Type : Animal Study
Additional Links
Substances : Perilla
Pharmacological Actions : Glucagon Like peptide 1 (GLP-1) Up-regulation
[+]

Perilla leaf extract ameliorates obesity and dyslipidemia induced by high-fat diet.Dec 01, 2009

Pubmed Data : Phytother Res. 2009 Dec;23(12):1685-90. PMID: 19444921
Article Published Date : Dec 01, 2009
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Dyslipidemias, Obesity
[+]

Perilla leaf extract attenuates asthma airway inflammation by blocking the syk pathway.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mediators Inflamm. 2021 ;2021:6611219. Epub 2021 May 10. PMID: 34045925
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Asthma
Pharmacological Actions : Anti-Asthmatic Agents, Anti-Inflammatory Agents
[+]

Perilla leaf extract attenuates COPD airway inflammation.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2021 ;12:763624. Epub 2022 Jan 4. PMID: 35058774
Article Published Date : Dec 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Perilla
Diseases : Chronic Obstructive Pulmonary Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Perilla leaf extract prevents atopic dermatitis induced by an extract of Dermatophagoides farinae in NC/Nga mice.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Allergy Immunol. 2016 Dec ;34(4):272-277. PMID: 27001658
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Atopic Dermatitis
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Perilla oil alleviates high-fat diet-induced inflammation in the colon. Jul 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Med Food. 2020 Aug ;23(8):818-826. Epub 2020 Jun 17. PMID: 32552354
Article Published Date : Jul 31, 2020
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Gastrointestinal Inflammation, High Fat Diet
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Perilla seed oil Alleviates gut dysbiosis, intestinal inflammation and metabolic disturbance.Sep 08, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Sep 9 ;13(9). Epub 2021 Sep 9. PMID: 34579018
Article Published Date : Sep 08, 2021
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Dysbiosis, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Gastroprotective
[+]

Perilla seed oil demonstrates anti-asthmatic effects. Jan 01, 2007

Pubmed Data : Planta Med. 2007 Jan;73(1):53-8. PMID: 17315310
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Asthma
Pharmacological Actions : Leukotriene Antagonists
[+]

Purple perilla showed lipid lowering in adipocyte cells and prevented body weight gain in mice.Aug 31, 2018

Pubmed Data : J Food Sci. 2018 Sep ;83(9):2384-2393. Epub 2018 Aug 2. PMID: 30070698
Article Published Date : Aug 31, 2018
Study Type : Animal Study
Additional Links
Substances : Perilla , Rosmarinic acid
Diseases : High Fat Diet, Obesity
Pharmacological Actions : Hypolipidemic
Additional Keywords : Anti-Obesity Agents, Phytotherapy, Plant Extracts
[+]

Sedative and hypnotic effects of Perilla frutescens essential oil through GABAergic system pathway.Nov 23, 2020

Pubmed Data : J Ethnopharmacol. 2020 Nov 24:113627. Epub 2020 Nov 24. PMID: 33246117
Article Published Date : Nov 23, 2020
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Insomnia
Pharmacological Actions : Hypnotics and Sedatives
Additional Keywords : Essential Oils
[+]

Sedative effects of inhaled Perilla frutescens essential oils.Feb 11, 2021

Pubmed Data : J Nat Med. 2021 Feb 12. Epub 2021 Feb 12. PMID: 33580405
Article Published Date : Feb 11, 2021
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Insomnia
Pharmacological Actions : Hypnotics and Sedatives
Additional Keywords : Essential Oils
[+]

The anti-tussive, anti-inflammatory effects and sub-chronic toxicological evaluation of perilla seed oil.Mar 14, 2021

Pubmed Data : J Sci Food Agric. 2021 Mar 15 ;101(4):1419-1427. Epub 2020 Sep 14. PMID: 32833246
Article Published Date : Mar 14, 2021
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antitussive Agents
[+]

The essential oil derived from Perilla frutescens attenuates imiquimod-induced psoriasis-like skin lesions.May 06, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2022 May 7 ;27(9). Epub 2022 May 7. PMID: 35566346
Article Published Date : May 06, 2022
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Psoriasis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interferon Gamma Reducer, Interleukin-23 Downregulation, Interleukin-6 Downregulation
Additional Keywords : Essential Oils
[+]

The promotion of hair regrowth by topical application of a Perilla frutescens extract.Dec 31, 2017

Pubmed Data : J Nat Med. 2018 Jan ;72(1):96-105. Epub 2017 Sep 13. PMID: 28905175
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Hair Loss
Additional Keywords : Hair Regeneration
[+]

This suggests that Perilla frutescens leaf can counteract vascular dementia-associated structural and functional deterioration.Jan 07, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Issues Mol Biol. 2022 Jan 8 ;44(1):257-272. Epub 2022 Jan 8. PMID: 35723398
Article Published Date : Jan 07, 2022
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Brain Inflammation , Dementia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Water extracts of perilla leaves could significantly suppress Th2 responses and airway inflammation in allergic murine model of asthma.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:324265. Epub 2015 Apr 20. PMID: 26064160
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Asthma
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory
Additional Keywords : Plant Extracts
[+]

A methoxyflavanone derivative from Perilla frutescens induces p53-mediated G2/M cell cycle arrest and apoptosis in A549 human lung adenocarcinoma.Jul 13, 2017

Pubmed Data : Cytotechnology. 2017 Jul 14. Epub 2017 Jul 14. PMID: 28710570
Article Published Date : Jul 13, 2017
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Lung Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Tumor Suppressor Protein p53 Upregulation
[+]

A methoxyflavanone from Perilla frutescens induces cellular senescence in A549 human lung adenocarcinoma cells.Aug 17, 2022

Pubmed Data : Biol Pharm Bull. 2022 Aug 18. Epub 2022 Aug 18. PMID: 35979561
Article Published Date : Aug 17, 2022
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Lung Cancer
Pharmacological Actions : Antiproliferative , P21 Activation, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Selective Antiproliferation
[+]

Anti-inflammatory constituents from Perilla frutescens on lipopolysaccharide-stimulated RAW264.7 cells.Sep 30, 2018

Pubmed Data : Fitoterapia. 2018 Oct ;130:61-65. Epub 2018 Aug 16. PMID: 30121232
Article Published Date : Sep 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Anti-inflammatory effects of Perilla frutescens in activated human neutrophils.Dec 13, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 Dec 14 ;5:18204. Epub 2015 Dec 14. PMID: 26659126
Article Published Date : Dec 13, 2015
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

Anti-osteoporosis effect of Perilla frutescens leaf hexane fraction through regulating osteoclast and osteoblast differentiation.Jan 25, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2022 Jan 26 ;27(3). Epub 2022 Jan 26. PMID: 35164085
Article Published Date : Jan 25, 2022
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Plant Extracts
[+]

Co-administration with nilotinib and perilla-derived methoxyflavanone significantly suppressed in vivo tumorigenicity of A549 cells in mice.Jul 28, 2017

Pubmed Data : Cytotechnology. 2017 Jul 29. Epub 2017 Jul 29. PMID: 28756527
Article Published Date : Jul 28, 2017
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Lung Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest
Additional Keywords : Natural Substance/Drug Synergy
[+]

Drying the leaves of Perilla frutescens increases their content of anticancer nutraceuticals.Mar 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2019 Apr ;7(4):1494-1501. Epub 2019 Mar 18. PMID: 31024723
Article Published Date : Mar 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Apigenin, Luteolin, Perilla
Diseases : Cancers: All
[+]

Extracts of Ficus carica and Perilla frutescens have potential for attenuating pathogens.Dec 31, 2013

Pubmed Data : Chemotherapy. 2014 ;60(5-6):379-83. Epub 2015 Oct 24. PMID: 26496663
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Fig, Perilla
Diseases : Gram-Negative Bacterial Infections, Pseudomonas aeruginosa
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Gene Expression Regulation, Multidrug Resistance, Plant Extracts
[+]

Extracts of Perilla frutescens leaves have antitumor effects on breast cancer cells.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:5619761. Epub 2021 Feb 15. PMID: 33628300
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Glycoglycerolipids from the leaves of Perilla frutescens and their anti-inflammatory activities in lipopolysaccharide-stimulated RAW264.7 cells.Mar 31, 2021

Pubmed Data : Phytochemistry. 2021 Apr ;184:112679. Epub 2021 Feb 5. PMID: 33550195
Article Published Date : Mar 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Isolation, characterization, and xanthine oxidase inhibitory activities of flavonoids from the leaves of Perilla frutescens.Jan 01, 2019

Pubmed Data : Nat Prod Res. 2019 Jan 2:1-7. Epub 2019 Jan 2. PMID: 30600717
Article Published Date : Jan 01, 2019
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Hyperuricemia
Pharmacological Actions : Xanthine oxidase inhibitor
[+]

Lemongrass and perilla essential oils synergistically increased antimicrobial activity.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Mycol J. 2021 ;62(4):79-87. PMID: 34853254
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Lemongrass, Perilla
Diseases : Bacillus subtilis infections
Pharmacological Actions : Antimicrobial
Additional Keywords : Essential Oils, Natural Substance Synergy
[+]

Melissa, Sweet Basil, Perilla, Prunella vulgaris and Savory has anti-HIV-1 activity. Jan 01, 1986

Pubmed Data : Zh Mikrobiol Epidemiol Immunobiol. 1986 Jan;(1):62-5. PMID: 9743251
Article Published Date : Jan 01, 1986
Study Type : In Vitro Study
Additional Links
Substances : Basil: Sweet, Melissa (Lemonbalm), Perilla , Prunella vulgaris, Savory
Diseases : HIV Infections
Pharmacological Actions : Reverse Transcriptase Inhibitors
Additional Keywords : Plant Extracts
[+]

Neuroprotective effect of Perilla extracts on PC12 cells.Jun 30, 2016

Pubmed Data : J Med Assoc Thai. 2016 Jul ;99 Suppl 4:S256-64. PMID: 29927179
Article Published Date : Jun 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Alzheimer's Disease, Brain: Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Neuroprotective effect of polysaccharide separated from Perilla frutescens.Apr 07, 2018

Pubmed Data : Biosci Biotechnol Biochem. 2018 Apr 8:1-15. Epub 2018 Apr 8. PMID: 29629628
Article Published Date : Apr 07, 2018
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Hydrogen Peroxide Induced Toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents
Additional Keywords : Polysaccharides
[+]

Perilla frutescens extracts enhance DNA repair response in UVB damaged HaCaT cells.Apr 11, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Apr 12 ;13(4). Epub 2021 Apr 12. PMID: 33921322
Article Published Date : Apr 11, 2021
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Aging Skin, DNA damage, Oxidative Stress, Ultraviolet Radiation Induced Damage
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Perilla frutescens: A rich source of pharmacological active compounds.Jun 01, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2022 Jun 2 ;27(11). Epub 2022 Jun 2. PMID: 35684514
Article Published Date : Jun 01, 2022
Study Type : Review
Additional Links
Substances : Perilla
Diseases : Alopecia: Androgenic, Alzheimer's Disease, Atopic Dermatitis, Diabetic Nephropathy, Diabetic Retinopathy, Gastrointestinal Inflammation, Hyperglycemia, Hyperuricemia, Inflammation, Parkinson's Disease, Periodontitis
Pharmacological Actions : Alpha-glucosidase inhibitor , Anti-Inflammatory Agents, Hypoglycemic Agents, Neuroprotective Agents
[+]

Perilla leaf extract inhibits growth and induces programmed cell death in human hepatoma cells. Jul 25, 2007

Pubmed Data : J Ethnopharmacol. 2007 Jul 25;112(3):557-67. Epub 2007 May 10. PMID: 17574356
Article Published Date : Jul 25, 2007
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Hepatoma
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Perilla leaf extract inhibits SARS-CoV-2 via direct virus inactivation.Jan 27, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed J. 2021 Jan 28. Epub 2021 Jan 28. PMID: 34119448
Article Published Date : Jan 27, 2021
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Coronavirus Infection
Pharmacological Actions : Antiviral Agents
[+]

Perilla leaf induces programmed cell death and cell cycle arrest in human leukemia cells. Jun 01, 2009

Pubmed Data : J Med Food. 2009 Jun;12(3):508-17. PMID: 19627198
Article Published Date : Jun 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Leukemia
Pharmacological Actions : Apoptotic, Cell cycle arrest
[+]

Perilla nutlet extracts may have potential to protect endothelium against vascular inflammation.May 28, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Rep. 2020 May 29 ;40(5). PMID: 32426811
Article Published Date : May 28, 2020
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Cardiovascular Diseases, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Phytochemical and phytopharmacological review of Perilla frutescens L. Sep 30, 2017

Pubmed Data : Food Chem Toxicol. 2017 Oct ;108(Pt B):375-391. Epub 2016 Nov 24. PMID: 27890564
Article Published Date : Sep 30, 2017
Study Type : Review
Additional Links
Substances : Perilla
Diseases : Allergies, Cancers: All, Cough, Depression, Oxidative Stress
Pharmacological Actions : Anti-Allergic Agents, Antidepressive Agents, Antimicrobial, Antioxidants
Additional Keywords : Phytotherapy
[+]

Protective effect of UV-irradiated red perilla on carbon tetrachloride-induced liver injury.May 17, 2022

Pubmed Data : Biosci Biotechnol Biochem. 2022 May 18. Epub 2022 May 18. PMID: 35583245
Article Published Date : May 17, 2022
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

Rosmarinic acid rich fraction may be further developed as an inhalation agent for the prevention of lung inflammation and cancer metastasis induced by PM exposure.Jul 22, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2021 Jul 23 ;11(8). Epub 2021 Jul 23. PMID: 34439757
Article Published Date : Jul 22, 2021
Study Type : In Vitro Study
Additional Links
Substances : Perilla , Rosmarinic acid
Diseases : Air Pollution Linked Toxicity, Lung Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic, Antioxidants, Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords : Risk Reduction
[+]

The antibacterial mechanism of perilla rosmarinic acid.Sep 06, 2021

Pubmed Data : Biotechnol Appl Biochem. 2021 Sep 7. Epub 2021 Sep 7. PMID: 34490944
Article Published Date : Sep 06, 2021
Study Type : In Vitro Study
Additional Links
Substances : Perilla , Rosmarinic acid
Diseases : Bacillus subtilis infections, Escherichia coli Infections, Salmonella Infections, Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents
[+]

The methanolic extract of Perilla frutescens robustly restricts ebola virus glycoprotein-mediated entry.Sep 07, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Viruses. 2021 Sep 8 ;13(9). Epub 2021 Sep 8. PMID: 34578374
Article Published Date : Sep 07, 2021
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Ebola
Pharmacological Actions : Antiviral Agents
[+]

The present review considers the literature on the effects of botanicals on BDNF. Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Plast. 2017 ;2017:5965371. Epub 2017 Dec 31. PMID: 29464125
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Substances : Ashwagandha, Bacopa, Coffee, Ginkgo biloba, Ginseng, Ginseng (Siberian), Grapes, Green Tea, Olive Oil, Perilla , Red Sage, Rhodiola (Tibetan Ginseng), Saffron
Diseases : Central Nervous System Diseases
Pharmacological Actions : Brain-derived neurotrophic factor modulator
[+]

The vapors from Oregano, Perilla, Tea Tree, Lavender, Clove, and Geranium essential oils have antifungal activity against Trichophyton mentagrophytes. Dec 01, 2006

Pubmed Data : J Infect Chemother. 2006 Dec;12(6):349-54. Epub 2007 Jan 18. PMID: 17235639
Article Published Date : Dec 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Clove, Geranium, Lavender, Oregano, Perilla , Tea Tree
Diseases : Fungal Infection, Trichophytosis
Pharmacological Actions : Antifungal Agents
[+]

These findings suggest that P. frutescens var. japonica and rosmarinic acid could prevent the progression of neurodegenerative diseases.Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomol Ther (Seoul). 2016 May 1 ;24(3):338-45. PMID: 27133263
Article Published Date : Apr 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Perilla , Rosmarinic acid
Diseases : Brain: Oxidative Stress, Hydrogen Peroxide Induced Toxicity, Neurodegenerative Diseases
Pharmacological Actions : Antioxidants, Cyclooxygenase 2 Inhibitors, Neuroprotective Agents

Copyright: marilyna / 123RF Stock Photo

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.
  • Printer-friendly version

Connect with GreenMedInfo

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2022 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.