Perilla

Views 412
Jump to
Abstracts Focused Research Topics
Download the GMI DOC on this Topic

Focus Your Research

Click any topic below to filter + focus research
17 Diseases Researched for Perilla
NameACCKFocus
Asthma24Locked
Allergic Rhinitis12Locked
Allergic Rhinoconjunctivitis12Locked
Cognitive Decline/Dysfunction12Locked
Depression12Locked
Dioxin Toxicity 12Locked
Dyslipidemias12Locked
Furan Toxicity 12Locked
Ileitis12Locked
Obesity12Locked
Fungal Infection11Locked
Gram-Negative Bacterial Infections11Locked
HIV Infections11Locked
Hepatoma11Locked
Leukemia11Locked
Pseudomonas aeruginosa11Locked
Trichophytosis11Locked
18 Pharmacological Actions Researched for Perilla
NameACCKFocus
Anti-Inflammatory Agents36Locked
Anti-Allergic Agents12Locked
Antidepressive Agents12Locked
Apoptotic22Locked
Cyclooxygenase 2 Inhibitors12Locked
Glucagon Like peptide 1 (GLP-1) Up-regulation12Locked
Immunomodulatory12Locked
Interleukin-1 beta downregulation12Locked
Interleukin-6 Downregulation12Locked
Interleukin-6 upregulation12Locked
Leukotriene Antagonists12Locked
NF-kappaB Inhibitor12Locked
Neuroprotective Agents12Locked
Anti-Bacterial Agents11Locked
Antifungal Agents11Locked
Antiproliferative 11Locked
Cell cycle arrest11Locked
Reverse Transcriptase Inhibitors11Locked

View the Evidence:
40 Abstracts with Perilla Research

[+]

Effectiveness of a nutraceutical supplement containing highly standardized perilla and ginger extracts in patients with functional dyspepsia.Feb 29, 2020

Pubmed Data : Minerva Gastroenterol Dietol. 2020 Mar ;66(1):35-40. PMID: 32283883
Article Published Date : Feb 29, 2020
Study Type : Human Study
Additional Links
Substances : Ginger, Perilla
Diseases : Dyspepsia
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Plant Extracts
[+]

Perilla frutescens leaf powder intake may be an effective intervention to prevent cardiovascular diseases.Apr 29, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Apr 30 ;25(9). Epub 2020 Apr 30. PMID: 32365849
Article Published Date : Apr 29, 2020
Study Type : Human Study
Additional Links
Substances : Alpha Linolenic Acid, Perilla
Diseases : Cardiovascular Diseases, Hypertension
Pharmacological Actions : Antihypertensive Agents, Cardioprotective
[+]

A diet containing P. frutescens extract effectively reversed learning and memory impairment induced by trimethyltin chloride.Oct 26, 2015

Pubmed Data : J Med Food. 2015 Oct 27. Epub 2015 Oct 27. PMID: 26505950
Article Published Date : Oct 26, 2015
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

A flavanone derivative Perilla frutescens potently suppresses IgE-mediated immediate hypersensitivity reactions.Jan 28, 2017

Pubmed Data : Biochem Biophys Res Commun. 2017 01 29 ;483(1):674-679. Epub 2016 Dec 13. PMID: 27986566
Article Published Date : Jan 28, 2017
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Allergic Rhinitis, Hypersensitivity: Immediate
Pharmacological Actions : Anti-Allergic Agents
[+]

A variety of vegetables reduce the absorption and enhance excretion of dioxin and furan toxins. May 01, 1999

Pubmed Data : Fukuoka Igaku Zasshi. 1999 May;90(5):171-83. PMID: 10396873
Article Published Date : May 01, 1999
Study Type : Animal Study
Additional Links
Substances : Broccoli, Cabbage, Chives, Kale, Onion, Perilla , Spinach, Vegetables: All
Diseases : Dioxin Toxicity , Furan Toxicity
[+]

Cold-pressed perilla oil has therapeutic potential in terms of protecting against skin photo-aging.Feb 21, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Feb 22 ;25(4). Epub 2020 Feb 22. PMID: 32098445
Article Published Date : Feb 21, 2020
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Aging Skin, Photooxidative Stress, Ultraviolet Radiation Induced Damage
Pharmacological Actions : Photoprotective
Additional Keywords : Plant Oils
[+]

Essential oil of P. frutescens administration exhibited significant antidepressant-like effects in mice with CUMS-induced depression.Sep 30, 2014

Pubmed Data : Chin J Nat Med. 2014 Oct ;12(10):753-9. Epub 2014 Oct 31. PMID: 25443368
Article Published Date : Sep 30, 2014
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents
Additional Keywords : Essential Oils
[+]

Omega-3 fatty acids (fish and perilla oil) are beneficial for small intestine inflammation associated with ileitis. Dec 01, 2009

Pubmed Data : Clin Exp Immunol. 2009 Dec;158(3):325-33. Epub 2009 Sep 30. PMID: 19793338
Article Published Date : Dec 01, 2009
Study Type : Animal Study
Additional Links
Substances : Fish Oil, Omega-3 Fatty Acids, Perilla
Diseases : Ileitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 upregulation
[+]

Perilla frutescens and its active compound rosmarinic acid have beneficial effects on cognitive improvement and may help prevent Alzheimer's disease.May 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res Pract. 2016 Jun ;10(3):274-81. Epub 2016 Apr 1. PMID: 27247723
Article Published Date : May 31, 2016
Study Type : Animal Study
Additional Links
Substances : Perilla , Rosmarinic acid
Diseases : Alzheimer's Disease
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor
[+]

Perilla frutescens and rosmarinic acid may play a role in ameliorating allergy diseases.Jan 01, 2011

Pubmed Data : Exp Biol Med (Maywood). 2011 Jan;236(1):99-106. PMID: 21239739
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Perilla , Rosmarinic acid
Diseases : Allergic Rhinitis, Allergic Rhinoconjunctivitis
Pharmacological Actions : Anti-Allergic Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor
Additional Keywords : Plant Extracts
[+]

Perilla frutescens extracts protects against dextran sulfate sodium-induced murine colitis.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2017 ;8:482. Epub 2017 Aug 8. PMID: 28848431
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, STAT3 Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Perilla frutescens leaf could be a potential therapeutic agent and food supplement for NSAID-induced gastric injuries.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2019 ;2019:9514703. Epub 2019 Mar 4. PMID: 30949513
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Perilla , Rosemaric Acid
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Gastroprotective
Problem Substances : Indomethacin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Perilla frutescens leaves attenuate dextran sulfate sodium-induced acute colitis.Dec 31, 2019

Pubmed Data : Food Sci Biotechnol. 2020 Jan ;29(1):131-140. Epub 2019 Nov 25. PMID: 31976135
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Perilla frutescens leaves extract ameliorates ultraviolet radiation-induced extracellular matrix damage.Jan 03, 2017

Pubmed Data : J Ethnopharmacol. 2017 Jan 4 ;195:334-342. Epub 2016 Nov 22. PMID: 27888134
Article Published Date : Jan 03, 2017
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Aging Skin, Ultraviolet Radiation Induced Damage
Pharmacological Actions : Photoprotective
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Perilla frutescens sprout displays beneficial effects in the prevention and treatment of type 2 diabetes.Jan 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res Pract. 2018 Feb ;12(1):20-28. Epub 2018 Jan 12. PMID: 29399293
Article Published Date : Jan 31, 2018
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
[+]

Perilla frutescens sprout extract may be useful for the prevention or treatment of diabetic nephropathy.Feb 07, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Feb 8 ;11(2). Epub 2019 Feb 8. PMID: 30744045
Article Published Date : Feb 07, 2019
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Diabetic Nephropathy, Kidney Fibrosis
Pharmacological Actions : Anti-Fibrotic, Renoprotective
[+]

Perilla increases glucagon-like peptide secretion.May 01, 2008

Pubmed Data : Biol Pharm Bull. 2008 May;31(5):1021-3. PMID: 18451539
Article Published Date : May 01, 2008
Study Type : Animal Study
Additional Links
Substances : Perilla
Pharmacological Actions : Glucagon Like peptide 1 (GLP-1) Up-regulation
[+]

Perilla leaf extract ameliorates obesity and dyslipidemia induced by high-fat diet.Dec 01, 2009

Pubmed Data : Phytother Res. 2009 Dec;23(12):1685-90. PMID: 19444921
Article Published Date : Dec 01, 2009
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Dyslipidemias, Obesity
[+]

Perilla leaf extract prevents atopic dermatitis induced by an extract of Dermatophagoides farinae in NC/Nga mice.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Allergy Immunol. 2016 Dec ;34(4):272-277. PMID: 27001658
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Atopic Dermatitis
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Perilla seed oil demonstrates anti-asthmatic effects. Jan 01, 2007

Pubmed Data : Planta Med. 2007 Jan;73(1):53-8. PMID: 17315310
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Asthma
Pharmacological Actions : Leukotriene Antagonists
[+]

Purple perilla showed lipid lowering in adipocyte cells and prevented body weight gain in mice.Aug 31, 2018

Pubmed Data : J Food Sci. 2018 Sep ;83(9):2384-2393. Epub 2018 Aug 2. PMID: 30070698
Article Published Date : Aug 31, 2018
Study Type : Animal Study
Additional Links
Substances : Perilla , Rosmarinic acid
Diseases : High Fat Diet, Obesity
Pharmacological Actions : Hypolipidemic
Additional Keywords : Anti-Obesity Agents, Phytotherapy, Plant Extracts
[+]

The promotion of hair regrowth by topical application of a Perilla frutescens extract.Dec 31, 2017

Pubmed Data : J Nat Med. 2018 Jan ;72(1):96-105. Epub 2017 Sep 13. PMID: 28905175
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Hair Loss
Additional Keywords : Hair Regeneration
[+]

Water extracts of perilla leaves could significantly suppress Th2 responses and airway inflammation in allergic murine model of asthma.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:324265. Epub 2015 Apr 20. PMID: 26064160
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Asthma
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory
Additional Keywords : Plant Extracts
[+]

A methoxyflavanone derivative from Perilla frutescens induces p53-mediated G2/M cell cycle arrest and apoptosis in A549 human lung adenocarcinoma.Jul 13, 2017

Pubmed Data : Cytotechnology. 2017 Jul 14. Epub 2017 Jul 14. PMID: 28710570
Article Published Date : Jul 13, 2017
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Lung Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Tumor Suppressor Protein p53 Upregulation
[+]

Anti-inflammatory constituents from Perilla frutescens on lipopolysaccharide-stimulated RAW264.7 cells.Sep 30, 2018

Pubmed Data : Fitoterapia. 2018 Oct ;130:61-65. Epub 2018 Aug 16. PMID: 30121232
Article Published Date : Sep 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Anti-inflammatory effects of Perilla frutescens in activated human neutrophils.Dec 13, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 Dec 14 ;5:18204. Epub 2015 Dec 14. PMID: 26659126
Article Published Date : Dec 13, 2015
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

Co-administration with nilotinib and perilla-derived methoxyflavanone significantly suppressed in vivo tumorigenicity of A549 cells in mice.Jul 28, 2017

Pubmed Data : Cytotechnology. 2017 Jul 29. Epub 2017 Jul 29. PMID: 28756527
Article Published Date : Jul 28, 2017
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Lung Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest
Additional Keywords : Natural Substance/Drug Synergy
[+]

Drying the leaves of Perilla frutescens increases their content of anticancer nutraceuticals.Mar 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2019 Apr ;7(4):1494-1501. Epub 2019 Mar 18. PMID: 31024723
Article Published Date : Mar 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Apigenin, Luteolin, Perilla
Diseases : Cancers: All
[+]

Extracts of Ficus carica and Perilla frutescens have potential for attenuating pathogens.Dec 31, 2013

Pubmed Data : Chemotherapy. 2014 ;60(5-6):379-83. Epub 2015 Oct 24. PMID: 26496663
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Fig, Perilla
Diseases : Gram-Negative Bacterial Infections, Pseudomonas aeruginosa
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Gene Expression Regulation, Multidrug Resistance, Plant Extracts
[+]

Isolation, characterization, and xanthine oxidase inhibitory activities of flavonoids from the leaves of Perilla frutescens.Jan 01, 2019

Pubmed Data : Nat Prod Res. 2019 Jan 2:1-7. Epub 2019 Jan 2. PMID: 30600717
Article Published Date : Jan 01, 2019
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Hyperuricemia
Pharmacological Actions : Xanthine oxidase inhibitor
[+]

Melissa, Sweet Basil, Perilla, Prunella vulgaris and Savory has anti-HIV-1 activity. Jan 01, 1986

Pubmed Data : Zh Mikrobiol Epidemiol Immunobiol. 1986 Jan;(1):62-5. PMID: 9743251
Article Published Date : Jan 01, 1986
Study Type : In Vitro Study
Additional Links
Substances : Basil: Sweet, Melissa (Lemonbalm), Perilla , Prunella vulgaris, Savory
Diseases : HIV Infections
Pharmacological Actions : Reverse Transcriptase Inhibitors
Additional Keywords : Plant Extracts
[+]

Neuroprotective effect of Perilla extracts on PC12 cells.Jun 30, 2016

Pubmed Data : J Med Assoc Thai. 2016 Jul ;99 Suppl 4:S256-64. PMID: 29927179
Article Published Date : Jun 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Alzheimer's Disease, Brain: Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Neuroprotective effect of polysaccharide separated from Perilla frutescens.Apr 07, 2018

Pubmed Data : Biosci Biotechnol Biochem. 2018 Apr 8:1-15. Epub 2018 Apr 8. PMID: 29629628
Article Published Date : Apr 07, 2018
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Hydrogen Peroxide Induced Toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents
Additional Keywords : Polysaccharides
[+]

Perilla leaf extract inhibits growth and induces programmed cell death in human hepatoma cells. Jul 25, 2007

Pubmed Data : J Ethnopharmacol. 2007 Jul 25;112(3):557-67. Epub 2007 May 10. PMID: 17574356
Article Published Date : Jul 25, 2007
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Hepatoma
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Perilla leaf induces programmed cell death and cell cycle arrest in human leukemia cells. Jun 01, 2009

Pubmed Data : J Med Food. 2009 Jun;12(3):508-17. PMID: 19627198
Article Published Date : Jun 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Leukemia
Pharmacological Actions : Apoptotic, Cell cycle arrest
[+]

Perilla nutlet extracts may have potential to protect endothelium against vascular inflammation.May 28, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Rep. 2020 May 29 ;40(5). PMID: 32426811
Article Published Date : May 28, 2020
Study Type : In Vitro Study
Additional Links
Substances : Perilla
Diseases : Cardiovascular Diseases, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Phytochemical and phytopharmacological review of Perilla frutescens L. Sep 30, 2017

Pubmed Data : Food Chem Toxicol. 2017 Oct ;108(Pt B):375-391. Epub 2016 Nov 24. PMID: 27890564
Article Published Date : Sep 30, 2017
Study Type : Review
Additional Links
Substances : Perilla
Diseases : Allergies, Cancers: All, Cough, Depression, Oxidative Stress
Pharmacological Actions : Anti-Allergic Agents, Antidepressive Agents, Antimicrobial, Antioxidants
Additional Keywords : Phytotherapy
[+]

The present review considers the literature on the effects of botanicals on BDNF. Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Plast. 2017 ;2017:5965371. Epub 2017 Dec 31. PMID: 29464125
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Substances : Ashwagandha, Bacopa, Coffee, Ginkgo biloba, Ginseng, Ginseng (Siberian), Grapes, Green Tea, Olive Oil, Perilla , Red Sage, Rhodiola (Tibetan Ginseng), Saffron
Diseases : Central Nervous System Diseases
Pharmacological Actions : Brain-derived neurotrophic factor modulator
[+]

The vapors from Oregano, Perilla, Tea Tree, Lavender, Clove, and Geranium essential oils have antifungal activity against Trichophyton mentagrophytes. Dec 01, 2006

Pubmed Data : J Infect Chemother. 2006 Dec;12(6):349-54. Epub 2007 Jan 18. PMID: 17235639
Article Published Date : Dec 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Clove, Geranium, Lavender, Oregano, Perilla , Tea Tree
Diseases : Fungal Infection, Trichophytosis
Pharmacological Actions : Antifungal Agents
[+]

These findings suggest that P. frutescens var. japonica and rosmarinic acid could prevent the progression of neurodegenerative diseases.Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomol Ther (Seoul). 2016 May 1 ;24(3):338-45. PMID: 27133263
Article Published Date : Apr 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Perilla , Rosmarinic acid
Diseases : Brain: Oxidative Stress, Hydrogen Peroxide Induced Toxicity, Neurodegenerative Diseases
Pharmacological Actions : Antioxidants, Cyclooxygenase 2 Inhibitors, Neuroprotective Agents

Copyright: marilyna / 123RF Stock Photo

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2020 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.