Phloretin

Name	AC	CK
Oxidative Stress	14	23
Inflammation	11	15
Acne	2	11
Aging Skin	1	10
Insulin Resistance	7	10
Ulcerative Colitis	5	10
Ultraviolet Radiation Induced Damage	1	10
Parkinson's Disease	3	9
Colon Cancer	7	8
Diabetic Complications	4	8
Endothelial Dysfunction	5	8
Breast Cancer	6	7
Diabetes Mellitus: Type 2	4	7
Liver Cancer	6	7
Melanoma	3	7
Staphylococcus aureus: Methicillin-resistant (MRSA)	3	7
Alzheimer's Disease	3	6
Colorectal Cancer	2	6
Kidney Damage	3	6
Nonalcoholic fatty liver disease (NAFLD)	3	6
Air Pollution Linked Toxicity	1	5
Brain Inflammation	3	5
Experimental Lung Inflammation	1	5
Lipopolysaccharide-Induced Toxicity	4	5
Salmonella Infections	4	5
Advanced Glycation End products (AGE)	3	4
Atherosclerosis	3	4
Chemotherapy-Induced Toxicity: Cisplatin	3	4
Diabetic Nephropathy	2	4
Hyperuricemia	2	4
Lung Cancer	4	4
Obesity	3	4
Osteoporosis	3	4
Cancers: All	3	3
Cancers: Drug Resistant	2	3
Carcinoma: Non-Small-Cell Lung	2	3
Cardiomyopathy	2	3
Chemotherapy-Induced Kidney Damage	2	3
Chemotherapy-Induced Toxicity: Doxorubicin	1	3
Chronic Obstructive Pulmonary Disease	2	3
Cognitive Decline/Dysfunction	1	3
Endothelial Damage	1	3
Escherichia coli Infections	2	3
High Fat Diet	2	3
Liver Damage	2	3
Memory Disorders: Sleep Deprivation Induced	1	3
Multiple Sclerosis	2	3
Oral Cancer	3	3
Prostatic Hyperplasia: Benign	2	3
Traumatic Brain Injury	2	3
Arsenic Poisoning	1	2
Arthritis	1	2
Asthma	1	2
Atopic Dermatitis	1	2
Brain Ischemia	1	2
Breast Cancer: Triple Negative	1	2
Candida Albicans	1	2
Cerebral Ischemia	1	2
Chemically-Induced Liver Damage	1	2
Chemotherapy-Induced Toxicity: Arsenic Trioxide	2	2
Colitis	1	2
Depression	1	2
Diabetic Neuropathy	1	2
Dysbiosis	1	2
Fatty Liver	1	2
Gastric Cancer	2	2
Glioblastoma	2	2
Gram-Negative Bacterial Infections	2	2
Heart Failure	1	2
Hepatic Steatosis	1	2
Hyperglycemia	2	2
Hyperlipidemia	1	2
Listeria Infections	2	2
Lung Inflammation	1	2
Memory Disorders	1	2
Mitochondrial Dysfunction	1	2
Myocardial Infarction	1	2
Necrotic Enteritis	1	2
Neurodegenerative Diseases	1	2
Osteoarthritis	1	2
Prostate Cancer	2	2
Pulmonary Hypertension	1	2
Sepsis	1	2
Skin Cancer	1	2
Staphylococcus aureus infection	2	2
Wound Healing	1	2
Bacterial Infections	1	1
Cancer Metastasis	1	1
Cancers: Multi-Drug Resistant	1	1
Cardiovascular Diseases	1	1
Cervical Cancer	1	1
Coronavirus Infection	1	1
Deep Vein Thrombosis	1	1
Esophageal Cancer	1	1
Gastroenteritis	1	1
Gastrointestinal Inflammation	1	1
Haemophilus influenzae	1	1
Hepatoma	1	1
Infection: Antibiotic Resistant	1	1
Leukemia: Acute promyelocytic leukemia	1	1
Lipid Peroxidation	1	1
Liver Cirrhosis	1	1
Liver Damage: Aflatoxin-Induced	1	1
Liver Fibrosis	1	1
Macular Degeneration	1	1
Pancreatic Cancer	1	1
Periodontitis	1	1
Porphyromonas gingivalis	1	1
Pseudomonas aeruginosa	1	1
Rheumatoid Arthritis	1	1
Steptococcus Mutans Infections	1	1
Streptococcus pneumoniae infection	1	1
Streptococcus pyogenes	1	1
Thrombosis	1	1
Tuberculosis	1	1
Vulvovaginitis: Infectious	1	1

Name	AC	CK
Anti-Inflammatory Agents	50	82
Antioxidants	37	69
Antiproliferative	24	31
NF-kappaB Inhibitor	15	30
Anti-Bacterial Agents	13	29
Interleukin-1 beta downregulation	11	24
Apoptotic	22	23
Cyclooxygenase 2 Inhibitors	7	23
Interleukin-6 Downregulation	12	22
Neuroprotective Agents	10	22
Tumor Necrosis Factor (TNF) Alpha Inhibitor	11	20
Prostaglandin PGE2 downregulation	4	18
Hepatoprotective	8	14
Renoprotective	7	13
Antimicrobial	3	12
Cardioprotective	6	11
Hypoglycemic Agents	7	11
Gastrointestinal Agents	5	10
Nrf2 activation	7	10
Photoprotective	1	10
Anti-metastatic	5	9
Chemopreventive	7	9
Immunomodulatory	6	9
Interleukin-8 downregulation	4	9
Cell cycle arrest	8	8
Hypolipidemic	4	8
Chemotherapeutic	3	7
Malondialdehyde Down-regulation	4	7
Chemoprotective Agents	5	6
Tumor Suppressor Protein p53 Upregulation	2	6
Angiogenesis Inhibitors	3	4
Anti-Apoptotic	3	4
Anti-Fibrotic	2	4
Bcl-2 protein down-regulation	3	4
Prophylactic Agents	3	4
Superoxide Dismutase Up-regulation	3	4
Anti-Glycation Agents	2	3
Anticarcinogenic Agents	2	3
Antineoplastic Agents	3	3
Catalase Up-Regulation	2	3
Cytoprotective	3	3
Glucose transporter-2 (GLUT2) expression down-regulation	2	3
Heme oxygenase-1 up-regulation	2	3
Matrix metalloproteinase-9 (MMP-9) inhibitor	3	3
Osteoprotective	2	3
Acetylcholinesterase Inhibitor	1	2
Adiponectin upregulation	1	2
Aldose reductase inhibitor	1	2
Anti-atherogenic	1	2
Antidepressive Agents	1	2
Antiviral Agents	2	2
Autophagy Up-regulation	2	2
Brain-derived neurotrophic factor modulator	1	2
Chemosensitizer	2	2
Gastroprotective	1	2
Insulin Sensitizers	1	2
Interferon Gamma Reducer	1	2
Interleukin-17 downregulation	1	2
Interleukin-2 Downregulation	1	2
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	1	2
Nitric Oxide Inhibitor	1	2
Nootropic Agents	1	2
Postaglandin PGE2 downregulation	2	2
STAT3 Inhibitor	1	2
Transforming growth factor beta (TGF-β) inhibitor	1	2
Alpha-glucosidase inhibitor	1	1
Anti-Angiogenic	1	1
Anti-Infective Agents	1	1
Autophagy Inhibitors	1	1
Cytotoxic	1	1
Heme oxygenase-1 inducer	1	1
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	1	1
Immunosuppressive Agents	1	1
Interleukin-12 downregulation	1	1
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	1
P-glycoprotein Inhibitors	1	1
Phase I Detoxification Enzyme Inducer	1	1
Phase II Detoxification Enzyme Inducer	1	1
Quorum Sensing Inhibition	1	1
Radiosensitizer	1	1
Remyelination	1	1
Survivin Down-Regulation	1	1
Vascular Endothelial Growth Factor Inhibitors	1	1

[+]

Phloretin inhibits the growth of P. acnes, P. granulosum, and S. epidermidis.Jan 31, 2016

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Pubmed Data : Int J Cosmet Sci. 2016 Feb ;38(1):85-92. Epub 2015 Aug 30. PMID: 26212527

Article Published Date : Jan 31, 2016

Study Type : Human In Vitro, Human Study

Additional Links

Substances : Phloretin

Diseases : Acne

Pharmacological Actions : Anti-Bacterial Agents, Antimicrobial, Cyclooxygenase 2 Inhibitors, Prostaglandin PGE2 downregulation

[+]

Protective effects of a topical antioxidant mixture against ultraviolet-induced photodamage in human skin.Nov 30, 2008

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Pubmed Data : J Cosmet Dermatol. 2008 Dec ;7(4):290-7. PMID: 19146606

Article Published Date : Nov 30, 2008

Study Type : Human Study

Additional Links

Substances : Ferulic acid, Phloretin, Vitamin C

Diseases : Aging Skin, Ultraviolet Radiation Induced Damage

Therapeutic Actions : Sunlight exposure

Pharmacological Actions : Antioxidants, Photoprotective

[+]

Antioxidant mixtures could prevent the harmful effects of ozone induced oxidative stress in human keratinocytes.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2015 ;10(8):e0131097. Epub 2015 Aug 13. PMID: 26270818

[+]

Low-dose phloretin alleviates diabetic atherosclerosis through endothelial KLF2 restoration.Dec 02, 2019

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Pubmed Data : Biosci Biotechnol Biochem. 2019 Dec 3:1-9. Epub 2019 Dec 3. PMID: 31791197

Article Published Date : Dec 02, 2019

Study Type : Animal Study

Additional Links

Substances : Phloretin

Diseases : Atherosclerosis, Diabetic Complications, Endothelial Dysfunction

Pharmacological Actions : Anti-atherogenic

[+]

Metagenomic signatures reveal the key role of phloretin in amelioration of gut dysbiosis.Dec 31, 2022

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Pubmed Data : Infect Immun. 2011 Dec ;79(12):4819-27. Epub 2011 Sep 19. PMID: 21930760

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Pubmed Data : Phytomedicine. 2020 Jan ;66:153111. Epub 2019 Oct 16. PMID: 31790902

Article Published Date : Dec 31, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Phloretin

Diseases : Hyperuricemia, Kidney Damage

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Renoprotective

[+]

Phloretin ameliorates testosterone-induced benign prostatic hyperplasia.Jul 25, 2021

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Phloretin could be a potential therapeutic treatment for COPD.Dec 11, 2017

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Pubmed Data : Int Immunopharmacol. 2017 Dec 12 ;55:112-119. Epub 2017 Dec 12. PMID: 29245072

Article Published Date : Dec 11, 2017

Study Type : Animal Study

Additional Links

Substances : Phloretin

Diseases : Chronic Obstructive Pulmonary Disease

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation

[+]

Phloretin is able to inhibit NSCLC A549 cell growth by inducing apoptosis.Nov 30, 2015

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Pubmed Data : Oncol Rep. 2015 Dec ;34(6):2871-9. PMID: 26503828

Article Published Date : Nov 30, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Phloretin

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation

[+]

Phloretin may be a potent reagent for hepatocellular carcinoma treatment. Oct 15, 2019

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Phloretin supplementation during PAH may mitigate PAH-associated physiological and biochemical alterations in broiler chickens.Sep 30, 2025

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Pubmed Data : Phytomedicine. 2014 Sep 15 ;21(10):1208-15. Epub 2014 Jun 2. PMID: 24932975

Article Published Date : Sep 14, 2014

Study Type : Animal Study

Additional Links

Substances : Phloretin

Diseases : Osteoporosis

Pharmacological Actions : Osteoprotective

Additional Keywords : Ovariectomy-Induced Changes

[+]

Phloretin-nanospanlastics for targeting the Akt/PI3K signaling pathways in dimethylhydrazine-induced colon cancer in mice.May 31, 2025

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Pubmed Data : Molecules. 2023 Feb 15 ;28(4). Epub 2023 Feb 15. PMID: 36838843

Article Published Date : Feb 14, 2023

Study Type : In Vitro Study

Additional Links

Substances : Phloretin

Diseases : High Fat Diet, Inflammation, Insulin Resistance, Obesity

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Anti-Obesity Agents

[+]

A review of the induced cytoprotective effects of Phloretin on mammalian cells.Dec 31, 2015

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Pubmed Data : Biofactors. 2016 Jan-Feb;42(1):13-40. Epub 2016 Jan 30. PMID: 26826024

Article Published Date : Dec 31, 2015

Study Type : Review

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Substances : Phloretin

Pharmacological Actions : Antioxidants, Cytoprotective

[+]

A systemic review of the pharmacological aspects and potential use of phloretin. Dec 31, 2018

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Pubmed Data : Mini Rev Med Chem. 2019 ;19(13):1060-1067. PMID: 30864525

Phloretin and Enalapril co-administration ameliorates hyperglycemia mediated exacerbation of myocardial injury.May 14, 2025

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Pubmed Data : Eur J Pharmacol. 2025 May 15 ;995:177394. Epub 2025 Feb 18. PMID: 39978711

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Pubmed Data : Exp Mol Pathol. 2022 Aug ;127:104814. Epub 2022 Jul 22. PMID: 35878674

Article Published Date : Jul 31, 2022

Study Type : In Vitro Study

Additional Links

Substances : Phloretin

Diseases : Glioblastoma

Pharmacological Actions : Apoptotic, Autophagy Up-regulation

[+]

Phloretin can enhance the killing effect of γδ T cells on SW-1116 cells.Dec 31, 2012

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Pubmed Data : Int Immunopharmacol. 2013 Jan ;15(1):6-14. Epub 2012 Nov 19. PMID: 23174508

Article Published Date : Dec 31, 2012

Study Type : In Vitro Study

Additional Links

Substances : Phloretin

Diseases : Colon Cancer

Pharmacological Actions : Immunomodulatory

[+]

Phloretin can inhibit BEL-7402 cells' malignant pheotype.Jun 30, 2008

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Pubmed Data : Molecules. 2015 ;20(12):21193-203. Epub 2015 Nov 27. PMID: 26633321

Article Published Date : Dec 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Apple, Phloretin

Diseases : Colon Cancer, Liver Cancer, Lung Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Phloretin has a strong chemopreventive effect against aflatoxin B1.Dec 31, 2011

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Pubmed Data : Biofactors. 2012 Jan-Feb;38(1):34-43. Epub 2012 Jan 18. PMID: 22253071

Pubmed Data : Nan Fang Yi Ke Da Xue Xue Bao. 2008 Jul ;28(7):1249-51. PMID: 18676276

Article Published Date : Jun 30, 2008

Study Type : In Vitro Study

Additional Links

Substances : Phloretin

Diseases : Liver Cancer

Pharmacological Actions : Apoptotic, Cell cycle arrest

[+]

Phloretin induces apoptosis of human esophageal cancer.Nov 30, 2017

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Pubmed Data : Molecules. 2023 Dec 13 ;28(24). Epub 2023 Dec 13. PMID: 38138556

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Pubmed Data : J Cardiovasc Pharmacol. 2015 May ;65(5):444-55. PMID: 25945863

Article Published Date : Apr 30, 2015

Study Type : In Vitro Study

Additional Links

Substances : Phloretin

Diseases : Atherosclerosis

Pharmacological Actions : Matrix metalloproteinase-9 (MMP-9) inhibitor

[+]

Phloretin may prove beneficial as a promising drug candidate for gastric cancer treatment.Dec 31, 2019

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Pubmed Data : J BUON. 2020 Jan-Feb;25(1):308-313. PMID: 32277647

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Pubmed Data : Free Radic Biol Med. 2024 Aug 20 ;221:283-295. Epub 2024 May 3. PMID: 38705496

Article Published Date : Aug 19, 2024

Study Type : In Vitro Study

Additional Links

Substances : Phloretin

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Superoxide Dismutase Up-regulation

[+]

Phloretin promotes lipolysis and inhibit inflammation in mouse 3T3-L1 cells.Sep 30, 2013

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Pubmed Data : Mol Nutr Food Res. 2013 Oct ;57(10):1803-13. Epub 2013 Jun 17. PMID: 23776070

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Pubmed Data : Methods. 2007 Aug;42(4):339-48. PMID: 18158826

Article Published Date : Aug 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Apples, Pear, Phloretin

Diseases : Colon Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Phloretin-induced apoptosis in B16 melanoma 4A5 cells and HL60 human leukemia cells.Mar 31, 1999

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View the Evidence: 165 Abstracts with Phloretin Research

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Phloretin inhibits the growth of P. acnes, P. granulosum, and S. epidermidis.Jan 31, 2016

Protective effects of a topical antioxidant mixture against ultraviolet-induced photodamage in human skin.Nov 30, 2008

Antioxidant mixtures could prevent the harmful effects of ozone induced oxidative stress in human keratinocytes.Dec 31, 2014

Phloretin has neuroprotective effects on rotenone-induced toxicity in human SH-SY5Y neuronal-like cells.Jul 07, 2017

Phloretin inhibits interleukin-1β-induced COX-2 and ICAM-1 in human lung epithelial cells.May 31, 2015

Phloretin might have a potential application in the development of treatment for MRSA infections.Jul 31, 2015

The apple polyphenol phloretin inhibits colorectal cancer cell growth.Sep 13, 2016

The combination of HSP70 with phloretin could be a novel treatment for efficient immunotherapy of intractable cancers such as skin melanoma.Dec 31, 2015

Phloretin alleviates doxorubicin-induced cardiotoxicity.Oct 31, 2023

Phloretin alleviates sleep deprivation-induced cognitive impairment by reducing inflammation.Nov 30, 2024

Phloretin ameliorates diabetes-induced endothelial injury through AMPK-dependent anti-EndMT pathway.Apr 30, 2022

Phloretin mitigates oxidative injury, inflammation and fibrogenic responses.May 20, 2022

Amorphous solid dispersion augments the bioavailability of phloretin and its therapeutic efficacy via targeting mTOR/SREBP-1c axis in NAFLD.Oct 31, 2023

Coenzyme Q10, biochanin A, and phloretin counteracted the neurotoxic effect due to Cr(VI) exposure in scavenging of free radicals.Aug 11, 2022

Combined phloretin and hPRP therapy is superior to either treatment alone in protecting the brain against TBD.Dec 31, 2023

Esculetin and phloretin combination mitigates acute kidney injury-diabetes comorbidity.Mar 29, 2025

Hepatotoxicity and endothelial dysfunction induced by high choline diet and the protective effects of phloretin in mice.Jul 31, 2016

Interplay between the gut microbiome and metabolism in ulcerative colitis Mice treated with the dietary ingredient phloretin.Oct 27, 2021

Low-dose phloretin alleviates diabetic atherosclerosis through endothelial KLF2 restoration.Dec 02, 2019

Metagenomic signatures reveal the key role of phloretin in amelioration of gut dysbiosis.Dec 31, 2022

Neuroprotective effect of phloretin in rotenone-induced mice model of Parkinson's disease.Nov 25, 2022

Phloretin alleviates Salmonella pullorum infection.Nov 24, 2025

Phloretin also acts as an inhibitor of E. coli O157:H7 biofilm formation as well as an anti-inflammatory agent in inflammatory bowel diseases.Nov 30, 2011

Phloretin ameliorates acetic acid induced colitis.Jan 23, 2020

Phloretin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by regulating the gut microbiota.Nov 01, 2019

Phloretin ameliorates diabetic nephropathy by inhibiting nephrin and podocin reduction through a non-hypoglycemic effect.May 26, 2022

Phloretin ameliorates heart function after myocardial infarction.Aug 31, 2023

Phloretin ameliorates hyperuricemia-induced chronic renal dysfunction.Dec 31, 2019

Phloretin ameliorates testosterone-induced benign prostatic hyperplasia.Jul 25, 2021

Phloretin and phloridzin guard against cisplatin-induced nephrotoxicity in mice through inhibiting oxidative stress and inflammation.Dec 08, 2020

Phloretin and phlorizin mitigates inflammatory stress and alleviate adipose and hepatic insulin resistance.May 31, 2023

Phloretin as an add-on therapy to losartan attenuates diabetes-induced AKIOct 31, 2023

Phloretin attenuates allergic airway inflammation and oxidative stress in asthmatic mice.Dec 31, 2016

Phloretin attenuates behavior deficits and neuroinflammatory response in MPTP induced Parkinson's disease in mice.Jun 24, 2019

Phloretin attenuates the inflammatory and oxidative stress pathways that accompany lung injury in mice.Oct 31, 2016

Phloretin attenuation of hepatic steatosis via an improvement of mitochondrial dysfunction.Dec 12, 2021

Phloretin can be used in a potential combination therapy with metformin for the prevention and rescue of type 2 diabetes.Dec 09, 2019

Phloretin could be a potent and effective antiarthritis agent.Dec 31, 2015

Phloretin could be a potential therapeutic treatment for COPD.Dec 11, 2017

Phloretin could be a promising agent in the management of diabetic neuropathy.Apr 30, 2018

Phloretin decreases microglia-mediated synaptic engulfment to prevent chronic mild stress-induced depression.Dec 31, 2022

Phloretin exhibited neuroprotective effects in cerebral ischemia/reperfusion.Apr 14, 2015

Phloretin has nootropic, neuroprotective and neurotrophic activities in scopolamine induced memory impaired mice.Jul 31, 2015

Phloretin has potential as a dietary supplement targeting key therapeutic mechanisms in neurodegenerative disorders.Apr 22, 2018

Phloretin has the potential to be utilized as an alternative therapeutic agent for treating atopic dermatitis.Dec 31, 2019

Phloretin improved glucose and lipid metabolism in rats with STZ-induced diabetes.Dec 31, 2016

Phloretin inhibited the pathogenicity and virulence factors against Candida albicans.Nov 30, 2021

Phloretin inhibits phorbol ester-induced tumor promotion and expression of cyclooxygenase-2 in mouse skin.Feb 29, 2012

Phloretin is able to inhibit NSCLC A549 cell growth by inducing apoptosis.Nov 30, 2015

Phloretin may be a potent reagent for hepatocellular carcinoma treatment. Oct 15, 2019

Phloretin may be a potential agent for the treatment of osteoarthritis.Nov 22, 2017

Phloretin might be a promising therapy for hyperuricemia‐related cardiovascular diseases.Sep 30, 2017

Phloretin might be able to increase insulin sensitivity and alleviate the metabolic diseases.Nov 30, 2014

Phloretin protects against cardiac damage and remodelling in a streptozotocin-induced diabetic model.May 09, 2019

Phloretin supplementation could improve growth performance and ameliorate intestinal injury in broilers with necrotic enteritis.Jun 30, 2025

Phloretin supplementation during PAH may mitigate PAH-associated physiological and biochemical alterations in broiler chickens.Sep 30, 2025

Phloretin suppresses intestinal inflammation and maintained epithelial tight junction integrity by modulating cytokines secretion in in vitro model of gut inflammation.Dec 31, 2022

Phloretin suppresses neuroinflammation by autophagy-mediated Nrf2 activation in macrophages.Jul 03, 2021

Phloretin was effective in preventing estrogen deficiency-induced osteoclastogenic resorption.Sep 14, 2014

Phloretin-nanospanlastics for targeting the Akt/PI3K signaling pathways in dimethylhydrazine-induced colon cancer in mice.May 31, 2025

Phloretin@cyclodextrin/natural silk protein/polycaprolactone nanofiber wound dressing with antioxidant and antibacterial activities promotes diabetic wound healing.Oct 31, 2024

Renoprotective effects of phloretin.Aug 31, 2025

Selected dietary components alone or in combination with other therapeutic approaches could prevent diabetes-related complications.Nov 30, 2016

The apple polyphenol phloretin inhibits breast cancer cell migration and proliferation.Dec 31, 2017

The modulatory role of phloretin in Aβ25-35 induced sporadic Alzheimer's disease in rat model.Nov 27, 2018

The natural dihydrochalcone phloretin reduces lipid accumulation.Jun 02, 2025

The present study evidenced strong anti-oxidant and anti-inflammatory effects of phloretin against tissue damage from CLP-induced sepsis.May 05, 2016

The protective role of phloretin against dextran sulfate sodium-induced ulcerative colitis in mice.Jan 02, 2019

Therapeutic delivery of phloretin by mixed emulsifier-stabilized nanoemulsion alleviated cerebral ischemia/reperfusion injury.Dec 10, 2025

Therapeutic effects of biochanin A, phloretin, and epigallocatechin-3-gallate in reducing oxidative stress in arsenic-intoxicated mice.Jan 05, 2021

Therapeutic effects of coenzymeQ10, biochanin A and phloretin against arsenic and chromium induced oxidative stress.Apr 30, 2022

These results provide direct evidence to support a possible use of phloretin for mitigation of obesity and maintenance of metabolic homeostasis.Feb 13, 2017

Phloretin

View the Evidence:
165 Abstracts with Phloretin Research