Pineapple

Name	AC	CK
Inflammation	18	41
Wound Healing	5	26
Lung Cancer	3	25
Breast Cancer	9	24
Burns	2	23
Hormone Imbalances: Low Melatonin	2	20
Osteoarthritis: Knee	2	20
Pain	1	20
Perineal trauma	1	20
Sinusitis	2	20
Coronavirus Infection	7	16
Osteoarthritis	4	15
Thrombosis	3	13
Cancers: All	7	12
Periodontitis	2	12
Celiac Disease	1	10
Chemotherapy-Induced Toxicity: Peripheral Neuropathy	1	10
Constipation: Post-Operative	1	10
Dental Care	1	10
Dyspepsia	1	10
Edema	1	10
Endothelial Dysfunction	1	10
Hypertension	1	10
Oral Surgical Procedures	1	10
Postoperative Edema	1	10
Postoperative Recovery	1	10
Prostatitis: Bacterial	1	10
Tooth Extraction: Wisdom	1	10
Xerostomia	1	10
Alzheimer's Disease	3	9
Colorectal Cancer	3	8
Inflammatory Bowel Diseases	4	6
Obesity	3	6
Oxidative Stress	3	6
Rheumatoid Arthritis	3	6
Tendon Injury	2	6
Asthma	3	5
Cervical Cancer	1	5
Allergic Airway Diseases	2	4
Aluminum Toxicity	2	4
Cancer Metastasis	1	4
Colitis	2	4
Colon Cancer	2	4
Diabetes Mellitus: Type 1	2	4
Diabetic Complications	2	4
High Fat Diet	2	4
Hyperlipidemia	2	4
Lipopolysaccharide-Induced Toxicity	4	4
Liver Damage	2	4
Neuropathic Pain	2	4
Non-Hodgkin Lymphoma	1	4
Chemotherapy-Induced Toxicity: Cisplatin	2	3
Diabetes Mellitus: Type 2	2	3
Liver Cirrhosis	1	3
Liver Fibrosis	1	3
Pancreatic Cancer	2	3
Skin Cancer	3	3
Ataxia	1	2
Atherosclerosis	1	2
Bisphenol Toxicity	1	2
Breastfeeding: Complications	1	2
Cadmium Poisoning	1	2
Chemically-Induced Liver Damage	1	2
Cognitive Decline/Dysfunction	1	2
Diabetes: Glycation/A1C	1	2
Drug-Induced Toxicity: Indomethacin	1	2
Gastric Cancer	2	2
Gastrointestinal Inflammation	1	2
Insulin Resistance	1	2
Kidney Damage: Chemically-Induced	1	2
Lactation Disorders	1	2
Lead Poisoning	1	2
Liver Cancer	2	2
Myocardial Infarction	1	2
Myocardial Ischemia	1	2
Nonalcoholic fatty liver disease (NAFLD)	1	2
Periodontal Diseases	1	2
Prostate Cancer	2	2
Sciatic Nerve Crush Injury	1	2
Sperm Quality: Low	1	2
Arthritis	1	1
Benzo[a]pyrene-induced Toxicity	1	1
Breast Cancer: Triple Negative	1	1
Burns: Severe	1	1
Cholangiocarcinoma	1	1
Cholera	1	1
Digestive System Diseases	1	1
Escherichia coli Infections	1	1
Glioma	1	1
Gram-Positive Bacterial Infections	1	1
Immune Disorders	1	1
Influenza	1	1
Intestinal Permeability	1	1
Leaky Gut Syndrome	1	1
Melanoma	1	1
Oral Cancer	1	1
Parkinson's Disease	1	1
Respiratory Diseases	1	1
Rotavirus Infections	1	1
Thrombophlebitis	1	1

Name	AC	CK
Anti-Inflammatory Agents	42	116
Analgesics	5	53
Antioxidants	14	35
Apoptotic	17	30
Anti-metastatic	5	28
Anti-Bacterial Agents	4	23
Tumor Necrosis Factor (TNF) Alpha Inhibitor	7	21
Interleukin-6 Downregulation	6	19
Interleukin-1 beta downregulation	5	17
Malondialdehyde Down-regulation	4	16
Neuroprotective Agents	7	16
Antiproliferative	10	15
NF-kappaB Inhibitor	10	14
Chemoprotective Agents	3	13
Immunomodulatory	4	13
Chemotherapeutic	3	12
Anti-Platelet	2	11
Hepatoprotective	5	11
Osteoprotective	1	10
Prostaglandin PGE2 downregulation	1	10
Antineoplastic Agents	4	8
Cyclooxygenase 2 Inhibitors	6	7
Antinoceceptive	3	6
Antiviral Agents	6	6
Interleukin-10 downregulation	3	6
Chemosensitizer	4	5
Hypoglycemic Agents	3	5
Autophagy Up-regulation	2	4
Hypolipidemic	2	4
Radiosensitizer	3	4
Anti-Fibrotic	1	3
Anticarcinogenic Agents	3	3
Anticoagulants	2	3
Cell cycle arrest	2	3
Chemopreventive	3	3
Chondroprotective	1	3
Interleukin-4 downregulation	2	3
Interleukin-8 downregulation	1	3
Matrix metalloproteinase-9 (MMP-9) inhibitor	2	3
Anti-Adipogenic	1	2
Anti-Allergic Agents	1	2
Anti-Anxiety Agents	1	2
Anti-Asthmatic Agents	1	2
Antimicrobial	2	2
Bcl-2 protein down-regulation	2	2
Cardioprotective	1	2
Cytoprotective	1	2
Cytotoxic	2	2
Gastrointestinal Agents	1	2
Gastroprotective	1	2
Immunostimulatory	2	2
Insulin Sensitizers	1	2
Interferon Gamma Reducer	1	2
Interleukin-12 downregulation	1	2
Interleukin-17 downregulation	1	2
Matrix metalloproteinase-3 (MMP-3) inhibitor	1	2
MicroRNA modulator	1	2
Postaglandin PGE2 downregulation	1	2
Radioprotective	1	2
Renoprotective	1	2
Tumor Suppressor Protein p53 Upregulation	2	2
Alpha-amylase inhibitor	1	1
Anti-thrombotic	1	1
Antifibrinolytic Agents	1	1
Thrombolytic	1	1

[+]

Bromelain-based enzymatic debridement versus standard of care in deep burn injuries.Sep 10, 2024

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Pubmed Data : J Burn Care Res. 2024 Sep 11. Epub 2024 Sep 11. PMID: 39259807

Article Published Date : Sep 10, 2024

Study Type : Meta Analysis, Review

Additional Links

Substances : Bromelain

Diseases : Burns

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A supplement with Ribes Nigrum, Boswellia Serrata, bromelain and vitamin D to stop local inflammation in chronic sinusitis.Apr 17, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Eur Rev Med Pharmacol Sci. 2010 Sep;14(9):771-4. PMID: 21061836

Article Published Date : Sep 01, 2010

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Pubmed Data : Sci Rep. 2023 Dec 1 ;13(1):21180. Epub 2023 Dec 1. PMID: 38040898

Article Published Date : Nov 30, 2023

Study Type : Human Study

Additional Links

Substances : Bromelain

Diseases : Celiac Disease

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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The effect of bromelain in periodontal surgery.May 12, 2023

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Pubmed Data : BMC Oral Health. 2023 May 13 ;23(1):286. Epub 2023 May 13. PMID: 37179311

Article Published Date : May 12, 2023

Study Type : Human Study

Additional Links

Substances : Bromelain

Diseases : Periodontitis

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These results showed the effectiveness of bromelain on episiotomy pain and wound healing.Feb 29, 2016

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Pubmed Data : Iran Red Crescent Med J. 2016 Mar ;18(3):e21019. Epub 2016 Mar 1. PMID: 27247780

Article Published Date : Feb 29, 2016

Study Type : Human Study

Additional Links

Substances : Bromelain, Pineapple

Diseases : Pain, Perineal trauma , Wound Healing

Pharmacological Actions : Analgesics

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Bromelain mitigates liver fibrosis via targeting hepatic stellate cells.May 31, 2023

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Pubmed Data : Tissue Cell. 2023 Jun ;82:102118. Epub 2023 May 27. PMID: 37269556

Article Published Date : May 31, 2023

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Bromelain

Diseases : Liver Cirrhosis, Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Antioxidants, Hepatoprotective

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Addition of bromelain and acetylcysteine to gemcitabine potentiates tumor inhibition in vivo in human colon cancer cell line LS174T.Dec 31, 2020

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Pubmed Data : Am J Transl Res. 2021 ;13(12):13524-13539. Epub 2021 Dec 15. PMID: 35035694

Article Published Date : Dec 31, 2020

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Pubmed Data : Neuropeptides. 2024 Jul 23 ;107:102455. Epub 2024 Jul 23. PMID: 39094391

Article Published Date : Jul 22, 2024

Study Type : Animal Study

Additional Links

Substances : Bromelain

Diseases : Ataxia

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents

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Bromelain exerts anti-inflammatory effects in an ovalbumin-induced murine model of allergic airway disease.Sep 01, 2005

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Pubmed Data : Cell Immunol. 2005 Sep;237(1):68-75. Epub 2005 Dec 6. PMID: 16337164

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Pubmed Data : Am J Physiol Heart Circ Physiol. 2008 Mar;294(3):H1365-70. Epub 2008 Jan 11. PMID: 18192224

Article Published Date : Mar 01, 2008

Study Type : Animal Study

Additional Links

Substances : Bromelain

Diseases : Myocardial Infarction, Myocardial Ischemia

Pharmacological Actions : Apoptotic, Cardioprotective

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Bromelain has immunomodulatory properties. Dec 20, 2006

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Pubmed Data : Int Immunopharmacol. 2006 Dec 20;6(13-14):2038-46. Epub 2006 Sep 5. PMID: 17161360

Article Published Date : Dec 20, 2006

Study Type : Animal Study

Additional Links

Substances : Bromelain

Pharmacological Actions : Interleukin-10 downregulation

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Bromelain has the potential to reduce the side effects of BPA on the male reproductive system.Nov 30, 2022

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Pubmed Data : Andrologia. 2022 Dec ;54(11):e14584. Epub 2022 Sep 6. PMID: 36068179

Article Published Date : Nov 30, 2022

Study Type : Animal Study

Additional Links

Substances : Bromelain

Diseases : Bisphenol Toxicity, Oxidative Stress, Sperm Quality: Low

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation

Additional Keywords : Estrogen Receptor Beta

Problem Substances : Bisphenol A

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Bromelain increases milk yield, milk composition and has no adverse effects on mammary health in dairy goats.Apr 01, 2009

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Pubmed Data : Trop Anim Health Prod. 2009 Apr;41(4):493-8. Epub 2008 Jul 27. PMID: 18661260

Article Published Date : Apr 01, 2009

Study Type : Animal Study

Additional Links

Substances : Bromelain

Diseases : Breastfeeding: Complications, Lactation Disorders

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Bromelain inhibits the ability of colorectal cancer cells to proliferate via activation of ROS production and autophagy.Dec 31, 2018

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Pubmed Data : Biomed Res Int. 2022 ;2022:5342559. Epub 2022 Nov 21. PMID: 36452063

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Pubmed Data : Acta Biol Hung. 2015 Jun ;66(2):149-60. PMID: 26081271

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Pubmed Data : Metabol Open. 2021 Mar ;9:100077. Epub 2021 Jan 4. PMID: 33490944

Article Published Date : Feb 28, 2021

Study Type : Animal Study

Additional Links

Substances : Pineapple

Diseases : Cognitive Decline/Dysfunction, High Fat Diet

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

Nephroprotective role of bromelain against oxidative injury induced by aluminium.Oct 31, 2020

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Pubmed Data : Environ Toxicol Pharmacol. 2020 Nov ;80:103509. Epub 2020 Oct 1. PMID: 33010469

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Pubmed Data : Food Sci Biotechnol. 2018 Oct ;27(5):1429-1438. Epub 2018 Apr 11. PMID: 30319853

Article Published Date : Sep 30, 2018

Study Type : Animal Study

Additional Links

Substances : Pineapple

Diseases : Obesity

Pharmacological Actions : MicroRNA modulator

Additional Keywords : Anti-Obesity Agents

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Pineapple leaf extract has insulin sensitizing activity.Aug 01, 2006

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Pubmed Data : Comp Biochem Physiol C Toxicol Pharmacol. 2006 Aug;143(4):429-35. Epub 2006 Apr 28. PMID: 16753349

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Pubmed Data : Arch Razi Inst. 2021 11 ;76(5):1427-1436. Epub 2021 Nov 30. PMID: 35355740

Article Published Date : Jan 10, 2021

Study Type : Animal Study

Additional Links

Substances : Bromelain

Diseases : Cadmium Poisoning

Pharmacological Actions : Anti-Inflammatory Agents

Problem Substances : Cadmium

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Protein stem bromelain together with all-trans retinoic-acid (atRA), may be a potent modulator of obesity by repressing the PPARγ-regulated adipogenesis pathwayDec 31, 2011

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Pubmed Data : PLoS One. 2012 ;7(1):e30831. Epub 2012 Jan 24. PMID: 22292054

Article Published Date : Dec 31, 2011

Study Type : Animal Study

Additional Links

Substances : Bromelain

Diseases : Obesity

Pharmacological Actions : Anti-Adipogenic, Apoptotic

Additional Keywords : Anti-Obesity Agents

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Study of the radiosensitizing and radioprotective efficacy of bromelain.Dec 31, 2019

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Pubmed Data : Integr Cancer Ther. 2020 Jan-Dec;19:1534735420950468. PMID: 32783540

Article Published Date : Dec 31, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Bromelain

Diseases : Cancers: All

Pharmacological Actions : Radioprotective, Radiosensitizer

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The ameliorative effect of bromelain on STZ-induced type 1 diabetes.Nov 14, 2021

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Pubmed Data : Life Sci. 2021 Nov 15 ;285:119982. Epub 2021 Sep 27. PMID: 34592232

Article Published Date : Nov 14, 2021

Study Type : Animal Study

Additional Links

Substances : Bromelain

Diseases : Diabetes Mellitus: Type 1

Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Malondialdehyde Down-regulation

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The present study provides new insights into the potential therapeutic value of bromelain for the prevention and treatment of thrombosis-related diseases.May 31, 2022

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Pubmed Data : J Exp Clin Cancer Res. 2014 Nov 12 ;33:92. Epub 2014 Nov 12. PMID: 25425315

Article Published Date : Nov 11, 2014

Study Type : In Vitro Study

Additional Links

Substances : Bromelain, NAC (N-acetyl-L-cysteine)

Diseases : Gastric Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

Additional Keywords : Natural Substance Synergy

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Bromelain and Olea europaea (L.) leaf extract mediated alleviation of benzo(a)pyrene induced lung cancer.Apr 22, 2021

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Pubmed Data : Environ Sci Pollut Res Int. 2021 Apr 23. Epub 2021 Apr 23. PMID: 33893581

Article Published Date : Apr 22, 2021

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Pubmed Data : J Int Oral Health. 2014 Sep ;6(5):96-8. PMID: 25395802

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Pubmed Data : Chin Med. 2016 ;11:46. Epub 2016 Nov 15. PMID: 27891174

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Bromelain

Diseases : Breast Cancer: Triple Negative

Pharmacological Actions : Apoptotic, Chemosensitizer, Chemotherapeutic

Additional Keywords : Chemotherapeutic Synergy: Cisplatin

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Bromelain induces apoptosis-related cell death in breast cancer cells with increasing concentrations in vitro.Apr 01, 2012

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Pubmed Data : J Med Food. 2012 Apr ;15(4):344-9. Epub 2011 Dec 22. PMID: 22191568

Article Published Date : Apr 01, 2012

Study Type : In Vitro Study

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Pubmed Data : Integr Cancer Ther. 2019 Jan-Dec;18:1534735419880258. PMID: 31752555

Article Published Date : Dec 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Bromelain

Diseases : Breast Cancer

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-4 downregulation

Additional Keywords : Chemotherapeutic Synergy: Cisplatin

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Bromelain-cisplatin chemoherbal combination demonstrated synergistic in-vitro anticancer effect on human prostatic carcinoma cell line.Dec 31, 2019

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Evaluation of the radiosensitizing potency of bromelain for radiation therapy of 4T1 breast cancer cells.Dec 31, 2018

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Pubmed Data : J Med Signals Sens. 2019 Jan-Mar;9(1):68-74. PMID: 30967992

Article Published Date : Dec 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Bromelain

Diseases : Breast Cancer

Pharmacological Actions : Antiproliferative , Radiosensitizer

[+]

Herbal anti-inflammatory agents for skin disease.Jan 01, 2000

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Pubmed Data : Skin Therapy Lett. 2000 ;5(4):3-5. PMID: 10785407

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Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2006 Aug;31(15):1242-4. PMID: 17048566

Article Published Date : Aug 01, 2006

Study Type : In Vitro Study

Additional Links

Substances : Beta Sitosterol, Caffeic Acid, Pineapple

[+]

Pineapple bromelain induces apoptosis in mammary cancer cells.Sep 16, 2010

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Pubmed Data : Biofactors. 2010 Sep 16. Epub 2010 Sep 16. PMID: 20848558

Article Published Date : Sep 16, 2010

Study Type : In Vitro Study

Additional Links

Substances : Bromelain, Pineapple

Diseases : Breast Cancer

Pharmacological Actions : Apoptotic, Autophagy Up-regulation

Additional Keywords : Autophagy

[+]

Pineapple juice has been shown to be capable of deactivating rotavirus transmission.Apr 30, 2008

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Pubmed Data : J Food Prot. 2008 May ;71(5):1035-7. PMID: 18522042

Article Published Date : Apr 30, 2008

Study Type : Viral

Additional Links

Substances : Pineapple

Diseases : Rotavirus Infections

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2021 ;12:717757. Epub 2021 Aug 20. PMID: 34489706

Article Published Date : Dec 31, 2020

Study Type : In Vitro Study

Additional Links

Substances : Bromelain

Diseases : Coronavirus Infection

Pharmacological Actions : Antiviral Agents

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View the Evidence: 136 Abstracts with Pineapple Research

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Bromelain-based enzymatic debridement versus standard of care in deep burn injuries.Sep 10, 2024

A supplement with Ribes Nigrum, Boswellia Serrata, bromelain and vitamin D to stop local inflammation in chronic sinusitis.Apr 17, 2023

Benefits of a food supplement containing Boswellia serrata and bromelain for improving the quality of life in patients with osteoarthritis.Oct 31, 2019

Bromelain has anti-platelet properties.Feb 01, 2006

Bromelain has antimetastic protential as demonstrated in lung cancer cells - Article 1. Jan 01, 1988

Bromelain has no difference in reducing symptoms of mild-to-moderate knee OA after 4 weeks when compared with diclofenac.Sep 30, 2016

Bromelain is effective in treating postoperative edema after third molar surgery.Sep 01, 2010

Bromelain may benefit children diagnosed with acute sinusitis. Mar 01, 2005

Bromelain may benefit patients with postoperative constipation. Sep 01, 2007

Bromelain reduces mild acute knee pain and improves well-being in a dose-dependent fashion in an open study of otherwise healthy adults.Dec 01, 2002

Bromelain-loaded nanocomposites decrease inflammatory and cytotoxicity effects of gliadin on Caco-2 cells and peripheral blood mononuclear cells of celiac patients.Nov 30, 2023

Combined anthocyanins and bromelain supplement improves endothelial function and skeletal muscle oxygenation status.Jan 27, 2021

Common fruit provide a dietary source of melatonin.Jan 16, 2013

Efficacy of a drug composed of herbal extracts on postoperative discomfort after surgical removal of impacted mandibular third molar.Apr 30, 2019

Glucosylceramide extracted from pineapple may improve the moisture level and xerostomia symptoms.Aug 27, 2019

OPERA was able to improve CIPN symptoms in a prospective series of patients treated with neurotoxic chemotherapy.Feb 28, 2017

Sodium alginate, sodium bicarbonate, bromelain and essential oils have therapeutic value in the treatment of functional dyspepsia.Jun 01, 2009

The combination of serenoa repens, selenium, lycopene and bromelain are beneficial in patients with chronic bacterial prostatitis.Oct 04, 2016

The effect of bromelain in periodontal surgery.May 12, 2023

These results showed the effectiveness of bromelain on episiotomy pain and wound healing.Feb 29, 2016

This study thus clearly supports the clinical relevance of treatment of postoperative conditions with bromelain.Sep 05, 2016

Treatment of COVID-19 patients with quercetin: a prospective, single center, randomized, controlled trial.Dec 31, 2020

Tropical fruit consumption increases the serum melatonin concentrations and also raises the antioxidant capacity in the serum of healthy volunteers in proportion to serum melatonin levels.Oct 04, 2012

Use of an alfa-lipoic, Methylsulfonylmethane, Boswellia serrata and Bromelain dietary supplement (OPERA®) for aromatase inhibitors-related arthralgia management.Jun 05, 2022

Anti-cancer activity of bromelain nanoparticles by oral administration.Nov 30, 2014

Bromelain degrades Aβ1-42 monomers and soluble aggregates.Jan 22, 2018

Bromelain extract exerts antiarthritic effects via chondroprotection.Oct 22, 2021

Bromelain mitigates liver fibrosis via targeting hepatic stellate cells.May 31, 2023

Addition of bromelain and acetylcysteine to gemcitabine potentiates tumor inhibition in vivo in human colon cancer cell line LS174T.Dec 31, 2020

Ameliorative effects of bromelain on aluminum-induced Alzheimer's disease.Jan 31, 2023

Antinociceptive and neuroprotective effects of bromelain in chronic constriction injury-induced neuropathic pain.Dec 31, 2019

Apoptosis and metastasis inhibitory potential of pineapple vinegar against mouse mammary gland cells.Dec 31, 2018

Bromelain Ameliorates Atherosclerosis.Dec 28, 2022

Bromelain ameliorates D-galactosamine-induced acute liver injury.Nov 24, 2022

Bromelain ameliorates hepatic microcirculation after warm ischemia indicating it may have liver protective effects after injury. May 01, 2007

Bromelain and acetylcysteine alone and in combination with gemcitabine inhibit subcutaneous deposits of pancreatic cancer after intraperitoneal injection.Dec 31, 2020

Bromelain and fresh pineapple juice have a therapeutic effect in acute crush archilles tendon injury.Apr 01, 2011

Bromelain attenuates inflammation in an experimental mouse model of asthma. Mar 01, 2008

Bromelain decreases oxidative stress and Neuroinflammation and improves motor function in adult male rats with cerebellar Ataxia induced by 3-acetylpyridine.Jul 22, 2024

Bromelain exerts anti-inflammatory effects in an ovalbumin-induced murine model of allergic airway disease.Sep 01, 2005

Bromelain has a healing effect in acute crush Archilles tendon injury. Jan 01, 2009

Bromelain has a therapeutic effect in established allergic airway disease.Aug 31, 2012

Bromelain has cardioprotective properties against an experimental model of heart injury. Mar 01, 2008

Bromelain has immunomodulatory properties. Dec 20, 2006

Bromelain has the potential to reduce the side effects of BPA on the male reproductive system.Nov 30, 2022

Bromelain increases milk yield, milk composition and has no adverse effects on mammary health in dairy goats.Apr 01, 2009

Bromelain inhibits the ability of colorectal cancer cells to proliferate via activation of ROS production and autophagy.Dec 31, 2018

Bromelain loaded nano lipid carriers opens new avenue for development of novel effective therapeutic modality for rheumatoid arthritis management.Jan 31, 2021

Bromelain may be an option in periodontal therapy by regulating cytokine levels, improving the healing process, and reducing bone resorption.Jul 31, 2023

Bromelain mitigated electrolyte imbalance in chronic constricted injury of the sciatic nerve.Oct 25, 2019

Bromelain modulates liver injury, hematological, molecular, and biochemical perturbations induced by aluminum.Dec 31, 2021

Bromelain plus peroxidase reduces non-Hodgkin lymphoma progressionOct 07, 2019

Bromelain protects against cisplatin-induced ocular toxicity through mitigating oxidative stress and inflammation.Dec 12, 2021

Bromelain reduced pro-inflammatory mediators as a common pathway that mediate antinociceptive and anti-anxiety effects in a sciatic nerve ligation model.Jan 10, 2021

Bromelain represents a novel approach to the treatment of metal toxicity.May 31, 2015

Bromelain treatment decreases neutrophil migration to sites of inflammation.Jul 01, 2008

Dietary supplementation with fresh pineapple juice decreases inflammation and colonic neoplasia in mice with colitis.Dec 01, 2010

Effect of bromelain on mast cell numbers and degranulation in diabetic rat wound healing.Jul 31, 2022

Enhancement of the anti-inflammatory effect of bromelain by its immobilization on probiotic spore of Bacillus cereus.Nov 05, 2020

High-fat diet-induced memory impairment and anxiety-like behavior in rats attenuated by peel extract of Ananas comosus fruit.Feb 28, 2021

Nephroprotective role of bromelain against oxidative injury induced by aluminium.Oct 31, 2020

Pharmacological evaluation of bromelain in mouse model of Alzheimer's disease.Dec 31, 2021

Pineapple bromelain has anti-tumor properties superior to the chemo-agent 5-fluorouracil.Oct 01, 2007

Pineapple juice may possibly be used as anti-obesity candidate.Sep 30, 2018

Pineapple leaf extract has insulin sensitizing activity.Aug 01, 2006

Pineapple leaves have anti-diabetic, anti-dyslipidemic and anti-oxidative activites.Jan 01, 2005

Pineapple leaves have hypolipidemic activity in mice similar to statins.Mar 01, 2007

Protective effect of bromelain on corrosive burns.Dec 09, 2020

Protective effects of bromelain against cadmium-induced pulmonary intoxication.Jan 10, 2021

Protein stem bromelain together with all-trans retinoic-acid (atRA), may be a potent modulator of obesity by repressing the PPARγ-regulated adipogenesis pathwayDec 31, 2011

Study of the radiosensitizing and radioprotective efficacy of bromelain.Dec 31, 2019

The ameliorative effect of bromelain on STZ-induced type 1 diabetes.Nov 14, 2021

Pineapple

View the Evidence:
136 Abstracts with Pineapple Research