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Polyphenols
Views 8222
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Focused Research Topics
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Click any topic below to filter + focus research
304 Diseases Researched for Polyphenols
Name
AC
CK
Focus
Oxidative Stress
94
243
Cardiovascular Diseases
41
205
Hypertension
22
173
Inflammation
41
118
Obesity
31
102
Endothelial Dysfunction
15
99
Diabetes Mellitus: Type 2
16
72
Cholesterol: Oxidation
9
65
Insulin Resistance
9
58
Prostate Cancer
17
46
Hyperglycemia
11
45
Arteriosclerosis
7
44
HDL: Low
4
40
Breast Cancer
31
39
Cancers: All
32
39
DNA damage
14
37
Metabolic Diseases
7
36
Hyperlipidemia
13
35
Lipopolysaccharide-Induced Toxicity
14
34
Lipid Peroxidation
14
32
C-Reactive Protein
2
30
Atherosclerosis
11
28
High Cholesterol
6
27
Alzheimer's Disease
20
26
Neurodegenerative Diseases
22
26
Chemically-Induced Liver Damage
12
23
Radiation Induced Illness
9
23
Diarrhea
3
22
HIV Infections
4
22
Dysbiosis
3
21
Dysbiosis: Bifidobacteria Deficiency
3
21
Metabolic Syndrome X
8
21
All-Cause Mortality
2
20
Cholesterol: LDL/HDL ratio
2
20
Cognitive Decline/Dysfunction
6
20
Hemodialysis
1
20
Liver Cancer
10
20
Prostate: PSA Doubling
2
20
Parkinson's Disease
14
19
Adiponectin: Low Levels
5
18
Nonalcoholic fatty liver disease (NAFLD)
6
18
Aging
11
17
Colon Cancer
13
17
Diabetes Mellitus: Type 2: Prevention
3
17
Cardiovascular Disease
2
15
Dementia
6
15
High Fat Diet
8
15
Dyslipidemias
3
14
Escherichia coli Infections
4
14
Triglycerides: Elevated
3
13
Brain Inflammation
8
12
Dental Caries
3
12
Gallbladder Cancer
2
12
Cardiovascular Disease: Prevention
2
11
Erectile Dysfunction
2
11
Helicobacter Pylori Infection
2
11
Human T-Cell Lymphotrophic Virus type 1 associated disease
2
11
Prostate Cancer: Prevention
2
11
Sarcopenia
2
11
Sleep Disorders
2
11
Ultraviolet Radiation Induced Damage
6
11
AIDS
1
10
Adult T-cell leukemia/lymphoma (ATL)
1
10
Aflatoxicosis
1
10
Alcoholic Liver Disease
5
10
Angina Pectoris
1
10
Arterial Thickening
1
10
Bile Duct Cancer
1
10
Blood Pressure: High
1
10
Carotid Artery Narrowing
1
10
Common Cold
1
10
Constipation
1
10
Depression
7
10
Dermatitis: Contact
1
10
Diabetes: Cardiovascular Illness
1
10
Diarrhea: in Children
1
10
Fibromyalgia
1
10
Gastroenteritis
1
10
Heart Disease: Ischemic
1
10
Intima Media Thickening
1
10
Libido: Low
1
10
Lung Cancer
8
10
Lung Cancer: Prevention
1
10
Muscle Damage: Exercise-Induced
1
10
Myocardial Infarction
5
10
Neurofibromatosis
1
10
Obesity: Abdominal
1
10
Osteopenia
1
10
Overweight
1
10
Prostatitis: Acute
1
10
Pulmonary Diseases
1
10
Rotavirus Infections
1
10
Sexaul Dysfunction
1
10
Smoking
1
10
Systemic Lupus Erythematosus
1
10
Alcohol Toxicity
5
9
Breast Cancer: Triple Negative
7
9
Colorectal Cancer
5
9
Breast Cancer: Metastatic
4
8
Cadmium Poisoning
4
8
Colitis
4
8
Coronavirus Infection
8
8
Sepsis
3
8
Cancers: Drug Resistant
6
7
Cervical Cancer
6
7
Pancreatic Cancer
5
7
Cancers
2
6
Colorectal Cancer: Prevention
2
6
Diabetic Complications
4
6
Diabetic Nephropathy
3
6
Endotoxemia
3
6
Fatty Liver
3
6
Immune Disorders: Low Immune Function
3
6
Osteoporosis
4
6
Staphylococcus aureus infection
6
6
Aging Skin
4
5
Aging: Brain
3
5
Aging: Immunosenecence
3
5
Allergies
3
5
Anti-gliadin Antibodies: Elevated
1
5
Cancer Metastasis
4
5
Endothelial Damage
1
5
Food Allergies: Wheat
1
5
Hypercholesterolemia
3
5
Hypertension: Pulmonary
1
5
Inflammatory Bowel Diseases
4
5
Kidney Damage: Chemically-Induced
3
5
Liver Damage
3
5
Melanoma
4
5
Aluminum Toxicity
2
4
Breast Cancer: Lung Metastasis
2
4
Colon Cancer: Prevention
3
4
Food Allergies
2
4
Gastric Cancer
4
4
Gastric Ulcer
2
4
Glioma
3
4
High Fructose Diet
2
4
Hyperinsulinism
2
4
Hyperuricemia
2
4
Irritable Bowel Syndrome
2
4
Liver Damage: Drug-Induced
2
4
Oral Cancer
4
4
Periodontal Diseases
3
4
Stress
2
4
Advanced Glycation End products (AGE)
2
3
Bladder Cancer
3
3
Cataract
2
3
Chemotherapy-Induced Toxicity: Cisplatin
2
3
Cholera
2
3
Drug-Induced Toxicity: Indomethacin
2
3
High Homocysteine
2
3
Influenza
2
3
MRSA
2
3
Memory Disorders
2
3
Periodontitis
2
3
Pseudomonas aeruginosa
3
3
Snake Bite: Venom Toxicity
2
3
Steptococcus Mutans Infections
3
3
Ulcerative Colitis
2
3
Acetaminophen (Tylenol) Toxicity
1
2
Acute lymphoblastic leukemia (ALL)
2
2
Air Pollution Linked Toxicity
2
2
Alopecia
1
2
Amyotrophic Lateral Sclerosis
2
2
Anaphylaxis
1
2
Aneurysm: Aortic
1
2
Antibiotic Toxicity
1
2
Arsenic Poisoning
2
2
Autoimmune Diseases
1
2
Brain Injury: Hippocampal Damage
1
2
Cancers: Multi-Drug Resistant
2
2
Cancers: Radiation-Resistant
1
2
Cardiac Hypertrophy
1
2
Cerebral Ischemia
1
2
Chemical Exposure: Nitrobenzene
1
2
Chemotherapy-Induced Toxicity: Irinotecan
1
2
Clostridium Infections
2
2
Coronavirus Disease
2
2
Dermatitis
1
2
Diabetes: Cognitive Dysfunction
1
2
Diabetes: Oxidative Stress
2
2
Diabetic Retinopathy
2
2
Diesel Exhaust Particle Toxicity
1
2
Dioxin Toxicity
1
2
Drug-Induced Toxicity: Cyclosporine
1
2
Esophageal Cancer
2
2
Eye Diseases
2
2
Female
1
2
Fructose-Induced Toxicity
1
2
Gastrointestinal Inflammation
1
2
Gestational Diabetes
1
2
Giardiasis
2
2
Glaucoma
2
2
Hair Loss
1
2
Hashimoto's thyroiditis
1
2
Heavy Metal Toxicity
1
2
Hypersensitivity
1
2
Hypertension: Arterial
1
2
Hypothyroidism
1
2
IgA Deficiency
1
2
IgE-Mediated Hypersensitivity
1
2
Infertility: Aging Associated
1
2
Infertility: Female
1
2
Influenza A
2
2
Intestinal Diseases
1
2
Kidney Damage
1
2
Liver Damage: Aflatoxin-Induced
1
2
Liver Fibrosis
1
2
Low Immune Function: Thymus Dysfunction
1
2
Lung Injury: Acute
1
2
Lymphoma
1
2
Melanoma: Metastatic
1
2
Multiple Sclerosis
2
2
Mycobacterium tuberculosis
2
2
Myocarditis: Autoimmune
1
2
Nasopharyngeal Cancer
2
2
Neuroblastoma
2
2
Ovariectomy Associated Adverse Changes
1
2
Petroleum Exposure And Toxicity
1
2
Prostatic Hyperplasia: Benign
1
2
Psychiatric Disorders
2
2
Radiation Induced Illness: Bone Marrow
1
2
Retinal Degeneration: Light-Induced
2
2
Rheumatoid Arthritis
1
2
Schizophrenia
2
2
Skin Cancer
2
2
Skin Diseases: Photo-Aging
2
2
Surgery: Anesthesiology
1
2
Tetanus
1
2
Tumors
1
2
Vaccine-induced Toxicity
1
2
Acrylamide-induced toxicity
1
1
Asbestos Toxicity
1
1
Attention Deficit Disorder
1
1
Attention Deficit Hyperactivity Disorder
1
1
Autism Spectrum Disorders
1
1
Barrett Esophagus
1
1
Benzene Toxicity
1
1
Bladder Cancer: Prevention
1
1
Brain Ischemia
1
1
Brain: Microglial Activation
1
1
Breast Cancer: HER-2 Overexpressed
1
1
Candida Albicans
1
1
Candida Infection
1
1
Carcinoma: Non-Small-Cell Lung
1
1
Chemotherapy-Induced Toxicity: Doxorubicin
1
1
Chlamydia Infections
1
1
Chronic Obstructive Pulmonary Disease
1
1
Clotting
1
1
Coronary Artery Disease
1
1
Crohn's Disease
1
1
Cryptosporidiosis
1
1
Dengue
1
1
Diabetes
1
1
Diabetes Mellitus: Type 1
1
1
Diabetes Mellitus: Type 1: Prevention
1
1
Diabetes: Eye Disease
1
1
Drug-Induced Toxicity: Gastrointestinal
1
1
Ebola Virus Infections
1
1
Electromagnetic Radiation Mitigation
1
1
Epithelial Neoplasms: Malignant
1
1
Excitotoxicity
1
1
Eye Damage
1
1
Foodborne Pathogens: Prevention/Food Preservation
1
1
Fusobacterium Infections
1
1
Glioblastoma
1
1
H3N2 Infection
1
1
H5N1 Infection
1
1
Hepatoma
1
1
Herpes Simplex Virus Type 1
1
1
Herpes Simplex Virus Type 2
1
1
Human Papillomavirus (HPV)
1
1
Hyperpigmentation
1
1
Hypoglycemia
1
1
Infertility
1
1
Iron Overload
1
1
Kidney Cancer
1
1
Kidney Damage: Drug-Induced
1
1
Leukemia
1
1
Leukemia: Chronic Lymphocytic Leukemia (CLL)
1
1
Listeria Infections
1
1
Macular Degeneration
1
1
Malaria
1
1
Malignant Melanoma
1
1
Measles
1
1
Mercury Poisoning
1
1
Mesothelioma
1
1
Neurologic Disorders
1
1
Ovarian Cancer
1
1
Pancreatitis
1
1
Pesticide Toxicity
1
1
Photooxidative Stress
1
1
Promyelocytic leukemia
1
1
Protozoan Infections
1
1
Psoriasis
1
1
Salmonella Infections
1
1
Staphylococcal Infections
1
1
Sugar (Sucrose) Toxicity
1
1
Tertiary butyl hydroperoxide toxicity
1
1
Thrombosis
1
1
Urinary Tract Infections
1
1
Vibrio Infections
1
1
Vitamin A Deficiency
1
1
Zinc Deficiency
1
1
152 Pharmacological Actions Researched for Polyphenols
Name
AC
CK
Focus
Antioxidants
221
519
Anti-Inflammatory Agents
115
232
Antihypertensive Agents
20
154
Neuroprotective Agents
53
94
Antiproliferative
65
90
Cardioprotective
27
83
Chemopreventive
41
79
Tumor Necrosis Factor (TNF) Alpha Inhibitor
41
79
Gastrointestinal Agents
25
76
Hypolipidemic
20
74
Apoptotic
56
68
Anticholesteremic Agents
11
63
Hypoglycemic Agents
19
57
Hepatoprotective
30
56
NF-kappaB Inhibitor
28
55
Interleukin-6 Downregulation
30
50
Immunomodulatory
15
41
Superoxide Dismutase Up-regulation
10
41
Anticarcinogenic Agents
18
36
Interleukin-1 beta downregulation
22
36
Cell cycle arrest
24
34
Insulin Sensitizers
4
32
Anti-metastatic
25
31
MicroRNA modulator
15
29
Anti-Bacterial Agents
18
28
Radioprotective
11
26
Vasodilator Agents
4
25
Anti-Apoptotic
12
24
Antiviral Agents
14
24
Malondialdehyde Down-regulation
8
23
Cyclooxygenase 2 Inhibitors
14
22
Nrf2 activation
12
21
Antineoplastic Agents
13
19
Anti-atherogenic
3
14
Cytoprotective
8
14
Regenerative
11
13
Renoprotective
7
13
Antidiarrheals
2
12
Antioxidant
3
12
Angiotensin-Converting Enzyme Inhibitors
2
11
Matrix metalloproteinase-2 (MMP-2) inhibitor
7
11
Nitric Oxide Enhancer
2
11
Adiponectin upregulation
4
10
Anti-Allergic Agents
4
10
Chemotherapeutic
8
10
Enzyme Inhibitors
8
10
Hepatocyte growth factor (HGF) inhibitor
1
10
Matrix metalloproteinase-9 (MMP-9) inhibitor
7
10
Photoprotective
5
10
Vascular Endothelial Growth Factor Regulator
1
10
Antidepressive Agents
5
8
Chemosensitizer
8
8
Vascular Endothelial Growth Factor Inhibitors
3
8
Antimicrobial
6
7
Genoprotective
5
7
Heme oxygenase-1 up-regulation
4
7
Alpha-glucosidase inhibitor
5
6
Angiogenesis Inhibitors
2
6
Anti Inflammatory
2
6
Chemoprotective Agents
4
6
Gastroprotective
4
6
Nitric Oxide Inhibitor
4
6
Antilipemic Agents
1
5
Antioxidant Effects
1
5
Brain-derived neurotrophic factor modulator
3
5
Glucagon Like peptide 1 (GLP-1) Up-regulation
1
5
Anti-Ulcer Agents
2
4
Bcl-2 protein down-regulation
3
4
Cyclooxygenase Inhibitors
2
4
Interleukin-10 downregulation
2
4
Interleukin-12 downregulation
2
4
Osteoprotective
3
4
Tumor Suppressor Protein p53 Upregulation
4
4
Anti-Angiogenic
3
3
Anti-Glycation Agents
2
3
Anti-Tumor
2
3
Chelating Agents
2
3
Epidermal growth factor receptor (EGFR) inhibitor
2
3
Interleukin-8 downregulation
3
3
Matrix metalloproteinase-1 (MMP-1) inhibitor
2
3
Prophylactic Agents
2
3
Quorum Sensing Inhibition
3
3
Radiosensitizer
2
3
STAT3 Inhibitor
3
3
Acetylcholinesterase Inhibitor
2
2
Analgesics
1
2
Anti-Adipogenic
1
2
Anticoagulants
2
2
Antimutagenic Agents
2
2
Autophagy Inhibitors
1
2
Bax/Bcl2 Ratio: Decrease
1
2
Bone Density Conservation Agents
1
2
Caspase-3 Activation
1
2
Catalase Up-Regulation
1
2
Cyclin D1 Down-Regulation
2
2
Dermatologic Agents
1
2
Gluconeogenesis Inhibitor
2
2
Histone deacetylase inhibitor
2
2
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
2
2
Immunostimulatory
1
2
Interferon Gamma Reducer
1
2
Interleukin-10 upregulation
1
2
Interleukin-18 down-regulation
1
2
Interleukin-2 Downregulation
1
2
Interleukin-4 downregulation
1
2
Interleukin-5 downregulation
1
2
Leptin Down-Regulation
1
2
Matrix Metalloproteinases Inhibitors
1
2
Neuroplasticity enhancement
1
2
Phase II Detoxification Enzyme Inducer
1
2
Proteasome Inhibitors
2
2
Tyrosinase inhibitors
2
2
Vascular Cell Adhesion Molecule-1 Inhibitor
2
2
angiogenesis
1
2
interleukin-13 down-regulation
1
2
AMP-activated protein kinase modulation
1
1
Alpha-amylase inhibitor
1
1
Anti-HIV Agents
1
1
Anti-Infective Agents
1
1
Anti-Platelet
1
1
Antifungal Agents
1
1
Antigiardial agents
1
1
Antiparasitic Agents
1
1
Antiprotozoal Agents
1
1
Bax/Bcl2 ratio: Increase
1
1
DNA Repair Up-regulation
1
1
E-cadherin down-regulation
1
1
Estrogen Receptor Modulators
1
1
Fertility Agents
1
1
Forkhead Transcription Factor Family O (FOXO) Modulator
1
1
Glucose Uptake Optimization
1
1
Glutathione Upregulation
1
1
Heat Shock Protein Inducer
1
1
Insulin-releasing
1
1
Interleukin-1 alpha downregulation
1
1
Iron Chelating Agents
1
1
Leukotriene Antagonists
1
1
Matrix metalloproteinase-14 (MMP-14) inhibitor
1
1
Matrix metalloproteinase-16 (MMP-16) inhibitor
1
1
Matrix metalloproteinase-17 (MMP-17) inhibitor
1
1
Matrix metalloproteinase-8 (MMP-8) inhibitor
1
1
NF-E2-Related Factor-2 (Nrf2) Modulator
1
1
Neuritogenic
1
1
Neurominidase Inhibitor
1
1
P21 Activation
1
1
Pancreato Protective Agents
1
1
Protease Inhibitors
1
1
Topoisomerase II Inhibitor
1
1
Transforming growth factor beta (TGF-β) inhibitor
1
1
Tumor Suppressor Protein p73 Upregulation
1
1
Vascular Endothelial Growth Factor A Inhibitor
1
1
Wnt/β-catenin signaling pathway modulation
1
1
Research Articles
700
Cumulative Knowledge Score
1132
Overall Research Rating
EXCELLENT
View the Evidence:
785 Abstracts with Polyphenols Research
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[+]
Daily grape polyphenol intake can significantly reduce the systolic blood pressure in humans.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(9):e0137665. Epub 2015 Sep 16. PMID:
26375022
Article Published Date
: Dec 31, 2014
Study Type
: Meta Analysis
Additional Links
Substances
:
Grape
,
Polyphenols
Diseases
:
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
[+]
Endothelial function can be significantly improved in healthy adults in the initial 2 hours after intake of grape polyphenols.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2013 ;8(7):e69818. Epub 2013 Jul 24. PMID:
23894543
Article Published Date
: Dec 31, 2012
Study Type
: Meta Analysis
Additional Links
Substances
:
Polyphenols
Diseases
:
Cardiovascular Diseases
,
Endothelial Dysfunction
Pharmacological Actions
:
Cardioprotective
,
Vasodilator Agents
[+]
The effect of grape products containing polyphenols on C-reactive protein levels.
Sep 13, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Nutr. 2020 Sep 14:1-41. Epub 2020 Sep 14. PMID:
32921322
Article Published Date
: Sep 13, 2020
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Grape Seed Extract
,
Polyphenols
Diseases
:
C-Reactive Protein
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
There are statistically significant and meaningful differences in nutritional composition between organic and non-organic crops and crop based foods.
Jun 25, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Nutr. 2014 Jun 26:1-18. Epub 2014 Jun 26. PMID:
24968103
Article Published Date
: Jun 25, 2014
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Polyphenols
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Organic Versus Conventional Foods
,
Pesticide Residue In Foods
[+]
This review provides support for the use of polyphenol-rich interventions for improving cardiovascular risk markers in haemodialysis patients.
Dec 10, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Dec 11 ;9(12). Epub 2017 Dec 11. PMID:
29232891
Article Published Date
: Dec 10, 2017
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Cocoa
,
Polyphenols
,
Pomegranate
,
Turmeric
Diseases
:
Cardiovascular Diseases
,
Hemodialysis
Pharmacological Actions
:
Antihypertensive Agents
,
Cardioprotective
Additional Keywords
:
Risk Reduction
[+]
High polyphenol chocolate is effective in improving the atherosclerotic cholesterol profile in patients with diabetes by increasing HDL cholesterol and improving the cholesterol:HDL ratio.
Nov 01, 2010
Click here to read the entire abstract
Pubmed Data
: Diabet Med. 2010 Nov;27(11):1318-21. PMID:
20968113
Article Published Date
: Nov 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cholesterol: LDL/HDL ratio
,
Diabetes: Cardiovascular Illness
,
HDL: Low
[+]
Plasma polyphenols and antioxidants, oxidative DNA damage and endothelial function in a diet and wine intervention study in humans.
Dec 31, 1998
Click here to read the entire abstract
Pubmed Data
: Drugs Exp Clin Res. 1999 ;25(2-3):133-41. PMID:
10370876
Article Published Date
: Dec 31, 1998
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Red Wine
Diseases
:
Arteriosclerosis
,
DNA damage
,
Endothelial Dysfunction
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
28‐days of polyphenol supplementation modulates the acute JNK, BAD, and Bcl‐2 response to heavy resistance exercise.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Physiol Rep. 2018 Jan ;6(2). PMID:
29380956
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
Diseases
:
Muscle Damage: Exercise-Induced
Therapeutic Actions
:
Exercise: Resistance Training
Pharmacological Actions
:
Anti-Apoptotic
[+]
A Chinese green tea polyphenol extract has evident anti-plaque effect.
Sep 01, 2000
Click here to read the entire abstract
Pubmed Data
: Zhonghua Kou Qiang Yi Xue Za Zhi. 2000 Sep;35(5):383-4. PMID:
11780252
Article Published Date
: Sep 01, 2000
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Green Tea
,
Polyphenols
Diseases
:
Dental Caries
[+]
A citrus polyphenol extract improved both overweight process and correlated skeletal muscle mass metabolism.
Jun 02, 2015
Click here to read the entire abstract
Pubmed Data
: Int J Food Sci Nutr. 2015 Jun 3:1-7. Epub 2015 Jun 3. PMID:
26037199
Article Published Date
: Jun 02, 2015
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
Diseases
:
Obesity
Additional Keywords
:
Anti-Obesity Agents
,
Significant Treatment Outcome
[+]
A combination of polyphenols reduced diastolic pressure by potentiating eNOS activation and nitric oxide production.
Jun 09, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Clin Nutr. 2015 Jun 10. Epub 2015 Jun 10. PMID:
26059745
Article Published Date
: Jun 09, 2015
Study Type
: Human Study
Additional Links
Substances
:
Bilberry
,
Ginkgo biloba
,
Grape Seed Extract
,
Grapefruit peel extract
,
Green Tea
,
Polyphenols
,
Quercetin
,
Resveratrol
Diseases
:
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
,
Nitric Oxide Enhancer
Additional Keywords
:
Plant Extracts
,
Significant Treatment Outcome
[+]
A joint consumption of apple juice, natural antioxidants and polyphenols might provide mild favorable effects on cardiometabolic markers, as compared to apple polyphenols alone.
Nov 30, 2014
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2014 Dec ;53(8):1645-57. Epub 2014 Feb 16. PMID:
24531755
Article Published Date
: Nov 30, 2014
Study Type
: Human Study
Additional Links
Substances
:
Apples
,
Polyphenols
,
Vitamin C
Pharmacological Actions
:
Anticholesteremic Agents
,
Antioxidants
Additional Keywords
:
Fruit Juice
,
Natural Substance Synergy
[+]
A polyphenol and antioxidant rich fruit and vegetable concentrate has therapeutic value in HIV patients due to enhanced proliferation, which could restore disturbances in T-cell homeostasis.
Feb 01, 2004
Click here to read the entire abstract
Pubmed Data
: Eur J Clin Nutr. 2004 Feb;58(2):317-25. PMID:
14749753
Article Published Date
: Feb 01, 2004
Study Type
: Human Study
Additional Links
Substances
:
Fruit: All
,
Polyphenols
,
Vegetables: All
Diseases
:
AIDS
,
HIV Infections
Pharmacological Actions
:
Antioxidants
,
Immunomodulatory
[+]
A polyphenol content of the diet was associated with reduced mortality risk in a Mediterranean population.
Nov 27, 2017
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2017 Nov 28 ;48:87-95. Epub 2017 Nov 28. PMID:
29469027
Article Published Date
: Nov 27, 2017
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
Diseases
:
All-Cause Mortality
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
All-Cause Mortality
,
Anti-Inflammatory Agents
,
POLYPHENOLS
,
Risk Reduction
[+]
A polyphenol pattern provided by a diet containing specific plant products was associated with lower dementia risk.
May 28, 2018
Click here to read the entire abstract
Pubmed Data
: Neurology. 2018 May 29 ;90(22):e1979-e1988. Epub 2018 Apr 27. PMID:
29703769
Article Published Date
: May 28, 2018
Study Type
: Human Study
Additional Links
Substances
:
Berries: All
,
Nuts
,
Olive Oil
,
Polyphenols
,
Red Wine Extract
,
Vegetables: All
Diseases
:
Dementia
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Risk Reduction
[+]
A polyphenol-rich beverage reduces symptoms associated with the common cold.
Oct 01, 2010
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2010 Oct;104(8):1156-64. Epub 2010 May 21. PMID:
20487584
Article Published Date
: Oct 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Common Cold
[+]
A polyphenol-rich whole food supplement significantly effected the rate of PSA progression among men with prostate cancer.
Mar 10, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Prostate Cancer Prostatic Dis. 2014 Mar 11. Epub 2014 Mar 11. PMID:
24614693
Article Published Date
: Mar 10, 2014
Study Type
: Human Study
Additional Links
Substances
:
Broccoli
,
Green Tea
,
Polyphenols
,
Pomegranate
,
Turmeric
Diseases
:
Prostate: PSA Doubling
,
Prostate Cancer
Additional Keywords
:
Supplements
[+]
Administration of Pycnogenol leads in improvement of erectile function in patients with diabetes.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Bratisl Lek Listy. 2019 ;120(12):941-944. PMID:
31855055
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
,
Pycnogenol (Pine Bark)
Diseases
:
Diabetes Mellitus: Type 2
,
Erectile Dysfunction
Pharmacological Actions
:
Anticholesteremic Agents
,
Hypoglycemic Agents
[+]
An acute dose of cranberry beverages improved biomarkers of antioxidant status and inhibition of bacterial adhesion in urine.
Apr 30, 2014
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2014 May ;34(5):420-7. Epub 2014 Apr 5. PMID:
24916555
Article Published Date
: Apr 30, 2014
Study Type
: Human Study
Additional Links
Substances
:
Cranberry
,
Polyphenols
Diseases
:
Escherichia coli Infections
,
Oxidative Stress
Pharmacological Actions
:
Anti-Bacterial Agents
,
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
Anthocyanin-rich apples may influence immune function compared to control apples.
Mar 26, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2021 Mar 27 ;13(4). Epub 2021 Mar 27. PMID:
33801641
Article Published Date
: Mar 26, 2021
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Apple
,
Polyphenols
Pharmacological Actions
:
Gastrointestinal Agents
,
Immunomodulatory
[+]
Antioxidant protection from bioactive compounds present in fruit and vegetables could have an adjuvant role in fibromyalgia treatment.
Nov 20, 2016
Click here to read the entire abstract
Pubmed Data
: Int J Vitam Nutr Res. 2016 Nov 21:1-10. Epub 2016 Nov 21. PMID:
27866465
Article Published Date
: Nov 20, 2016
Study Type
: Human Study
Additional Links
Substances
:
Chocolate
,
Fruit: All
,
Polyphenols
,
Vegetables: All
Diseases
:
Fibromyalgia
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Risk Reduction
[+]
Apple peel extract inhibits the growth of Helicobacter pylori, and attenuates damage to the gastric mucosa caused by neutrophils.
Sep 09, 2009
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2009 Sep 9;57(17):7743-9. PMID:
19691323
Article Published Date
: Sep 09, 2009
Study Type
: Human Study
Additional Links
Substances
:
Apples
,
Flavonoids
,
Polyphenols
Diseases
:
Helicobacter Pylori Infection
Additional Keywords
:
Plant Extracts
,
Proanthocyanidins
[+]
Aronia berry polyphenol consumption reduces plasma total and low-density lipoprotein cholesterol
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2017 Jan ;37:67-77. Epub 2016 Dec 10. PMID:
28215316
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Chokeberry
,
Polyphenols
Diseases
:
Cardiovascular Diseases
,
Hypertension
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Hypolipidemic
Additional Keywords
:
Plant Extracts
[+]
Bilberry has anti-inflammatory properties.
Sep 01, 2010
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2010 Sep;49(6):345-55. Epub 2010 Feb 2. PMID:
20119859
Article Published Date
: Sep 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Bilberry
,
Flavonoids
,
Polyphenols
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
NF-kappaB Inhibitor
[+]
Black tea consumption can decrease postprandial blood glucose after sucrose intake.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asia Pac J Clin Nutr. 2017 Jan ;26(1):59-64. PMID:
28049262
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Black Tea
,
Polyphenols
Diseases
:
Hyperglycemia
Pharmacological Actions
:
Hypoglycemic Agents
[+]
Blood pressure is reduced and insulin sensitivity increased in glucose-intolerant, hypertensive subjects after 15 days of consuming high-polyphenol dark chocolate.
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2008 Sep;138(9):1671-6. PMID:
18716168
Article Published Date
: Sep 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cardiovascular Diseases
,
Hypertension
,
Insulin Resistance
[+]
Boswellia resin extract and propolis derived polyphenols can reduce genitourinary pain and then improve quality of life of men affected by prostatitis-like symptoms.
Jan 13, 2020
Click here to read the entire abstract
Pubmed Data
: Arch Ital Urol Androl. 2020 Jan 14 ;91(4):251-255. Epub 2020 Jan 14. PMID:
31937091
Article Published Date
: Jan 13, 2020
Study Type
: Human Study
Additional Links
Substances
:
Bee Propolis
,
Frankincense
,
Polyphenols
Diseases
:
Prostatitis: Acute
[+]
Brazilian native fruit juices decrease postprandial glycemia in healthy subjects.
Jan 10, 2017
Click here to read the entire abstract
Pubmed Data
: Food Res Int. 2017 10 ;100(Pt 2):196-203. Epub 2017 Aug 19. PMID:
28888441
Article Published Date
: Jan 10, 2017
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
Diseases
:
Hyperglycemia
Pharmacological Actions
:
Hypoglycemic Agents
Additional Keywords
:
Plant Extracts
[+]
Cocoa inhibits LDL oxidation both in vitro and ex vivo.
Apr 06, 1999
Click here to read the entire abstract
Pubmed Data
: Mutat Res. 1999 Apr 6;440(2):181-8. PMID:
11185658
Article Published Date
: Apr 06, 1999
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Arteriosclerosis
,
Cholesterol: Oxidation
Pharmacological Actions
:
Antioxidants
[+]
Cocoa-rich chocolate and body composition in postmenopausal women.
Jan 13, 2021
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2021 03 14 ;125(5):548-556. Epub 2020 Aug 4. PMID:
32746952
Article Published Date
: Jan 13, 2021
Study Type
: Human Study
Additional Links
Substances
:
Cocoa
,
Polyphenols
Diseases
:
Hypertension
,
Postmenopausal Disorders: Weight Gain/Obesity
Additional Keywords
:
Anti-Obesity Agents
[+]
Coffee appears to have a beneficial effect on pulmonary function, among non-smokers.
Oct 15, 2010
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2010 Oct 15;127(8):1758-68. PMID:
19372215
Article Published Date
: Oct 15, 2010
Study Type
: Human Study
Additional Links
Substances
:
Coffee
,
Flavonoids
,
Polyphenols
Diseases
:
Pulmonary Diseases
,
Smoking
[+]
Coffee bean polyphenols ameliorate postprandial endothelial dysfunction in healthy male adults.
May 01, 2015
Click here to read the entire abstract
Pubmed Data
: Int J Food Sci Nutr. 2015 May ;66(3):350-4. Epub 2015 Feb 10. PMID:
25666414
Article Published Date
: May 01, 2015
Study Type
: Human Study
Additional Links
Substances
:
Coffee
,
Polyphenols
Diseases
:
Endothelial Dysfunction
[+]
Coffee polyphenols extracted from green coffee beans improve skin properties and microcirculatory function.
Aug 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biosci Biotechnol Biochem. 2017 Sep ;81(9):1814-1822. Epub 2017 Jul 4. PMID:
28675091
Article Published Date
: Aug 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Coffee
,
Coffee: Green/Unroasted
,
Polyphenols
[+]
Consumption of a polyphenol-rich grape-wine extract lowers ambulatory blood pressure in mildly hypertensive subjects.
Apr 29, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2015 Apr 30 ;7(5):3138-53. Epub 2015 Apr 30. PMID:
25942487
Article Published Date
: Apr 29, 2015
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Catechin
,
Polyphenols
Diseases
:
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
Additional Keywords
:
Plant Extracts
[+]
Consumption of either NPJ or HPJ protected against DNA damage and lipid peroxidation, modified several antioxidant enzymes, and reduced body weight.
Jul 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2015 Aug ;145(8):1808-16. Epub 2015 Jul 1. PMID:
26136593
Article Published Date
: Jul 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Oranges
,
Polyphenols
Diseases
:
Lipid Peroxidation
,
Obesity
Pharmacological Actions
:
Antihypertensive Agents
,
Antioxidants
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Anti-Obesity Agents
,
Orange Juice
[+]
Consumption of mango improves symptoms and associated biomarkers of constipation beyond an equivalent amount of fiber.
May 06, 2018
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2018 May 7:e1701034. Epub 2018 May 7. PMID:
29733520
Article Published Date
: May 06, 2018
Study Type
: Human Study
Additional Links
Substances
:
Mango
,
Polyphenols
Diseases
:
Constipation
[+]
Consumption of olive oil polyphenols decreased plasma LDL concentrations and LDL atherogenicity in healthy young men.
Jun 30, 2015
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2015 Jul 1. Epub 2015 Jul 1. PMID:
26136585
Article Published Date
: Jun 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Olive Oil
,
Polyphenols
Diseases
:
Atherosclerosis
,
Cholesterol: Oxidation
,
High Cholesterol
,
Oxidative Stress
Pharmacological Actions
:
Anticholesteremic Agents
,
Antioxidants
Additional Keywords
:
Dietary Modification
,
Risk Reduction
[+]
Consumption of phytochemical-rich foods may prevent the development of hypertension.
Feb 28, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Clin Nutr. 2015 Mar ;69(3):392-8. Epub 2014 Nov 12. PMID:
25387902
Article Published Date
: Feb 28, 2015
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Hypertension
Additional Keywords
:
Dietary Modification
,
Plant Extracts
,
Risk Reduction
[+]
Consumption of polyphenols results in a significant improvement in an established marker of cardiovascular risk in hypertensive participants.
May 09, 2016
Click here to read the entire abstract
Pubmed Data
: Heart. 2016 May 10. Epub 2016 May 10. PMID:
27164919
Article Published Date
: May 09, 2016
Study Type
: Human Study
Additional Links
Substances
:
Berries: All
,
Chocolate
,
Fruit: All
,
Polyphenols
,
Vegetables: All
Diseases
:
Cardiovascular Diseases
,
Hypertension
Additional Keywords
:
Risk Reduction
[+]
Continuous intake of polyphenolic compounds containing cocoa powder reduces LDL oxidative susceptibility and has beneficial effects on plasma HDL-cholesterol concentrations in humans.
Jun 02, 2009
Click here to read the entire abstract
Pubmed Data
: Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):9033-8. Epub 2009 May 18. PMID:
17344491
Article Published Date
: Jun 02, 2009
Study Type
: Human Study
Additional Links
Substances
:
Catechin
,
Flavonoids
,
Polyphenols
Diseases
:
Cholesterol: Oxidation
,
HDL: Low
Pharmacological Actions
:
Antioxidants
[+]
Dark chocolate consumption increases HDL cholesterol concentration and chocolate fatty acids may inhibit lipid peroxidation in healthy humans.
Dec 01, 2008
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol.2008 Dec;46(12):3586-92. Epub 2008 Sep 3 PMID:
15454274
Article Published Date
: Dec 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Chocolate
,
Flavonoids
,
Polyphenols
Diseases
:
Cholesterol: LDL/HDL ratio
,
Cholesterol: Oxidation
,
HDL: Low
[+]
Dietary polyphenol intake is associated with biological aging, a novel predictor of cardiovascular disease.
May 16, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2021 May 17 ;13(5). Epub 2021 May 17. PMID:
34067821
Article Published Date
: May 16, 2021
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
Diseases
:
Aging
,
Cardiovascular Diseases
Pharmacological Actions
:
Antioxidants
[+]
Diets rich in polyphenols and omega-3s improve postprandial dyslipidemia and oxidative stress.
Mar 01, 2014
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2014 Mar ;99(3):463-71. Epub 2013 Dec 24. PMID:
24368433
Article Published Date
: Mar 01, 2014
Study Type
: Human Study
Additional Links
Substances
:
Omega-3 Fatty Acids
,
Polyphenols
Diseases
:
Dyslipidemias
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hypolipidemic
[+]
Fruit and vegetable consumption and their polyphenol content are inversely associated with sleep duration.
Nov 19, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2018 Nov 20 ;10(11). Epub 2018 Nov 20. PMID:
30463296
Article Published Date
: Nov 19, 2018
Study Type
: Human Study
Additional Links
Substances
:
Fruit: All
,
Polyphenols
,
Vegetables: All
Diseases
:
Sleep Disorders
[+]
Gazpacho soup consumption is associated with a lower prevalence of hypertension.
Sep 30, 2013
Click here to read the entire abstract
Pubmed Data
: Nutr Metab Cardiovasc Dis. 2013 Oct ;23(10):944-52. Epub 2012 Nov 11. PMID:
23149074
Article Published Date
: Sep 30, 2013
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
,
Soup
Diseases
:
Cardiovascular Diseases
,
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
Additional Keywords
:
Natural Substance Synergy
[+]
Grape polyphenols reduce blood pressure and increase flow-mediated vasodilation in men with metabolic syndrome.
Aug 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2012 Sep ;142(9):1626-32. Epub 2012 Jul 18. PMID:
22810991
Article Published Date
: Aug 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Grape
,
Polyphenols
Diseases
:
Endothelial Dysfunction
,
Hypertension
,
Metabolic Syndrome X
Pharmacological Actions
:
Antihypertensive Agents
[+]
Grape pomace phenolic extract reduces trimethylamine-n-oxide levels in humans.
Jan 10, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Jan 10 ;11(1). Epub 2019 Jan 10. PMID:
30634687
Article Published Date
: Jan 10, 2019
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
,
Resveratrol
Diseases
:
Cardiovascular Diseases
Additional Keywords
:
Plant Extracts
[+]
Grape pomace polyphenols and pectin reduce trimethylamine-n-oxide serum levels.
Jan 01, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2019 ;10:575. Epub 2019 May 21. PMID:
31164827
Article Published Date
: Jan 01, 2019
Study Type
: Human Study
Additional Links
Substances
:
Pectin
,
Polyphenols
Diseases
:
Cardiovascular Disease
[+]
Grape pomace polyphenols reduce postprandial insulin levels and improve insulin sensitivity.
Jan 12, 2019
Click here to read the entire abstract
Pubmed Data
: Clin Nutr. 2019 12 ;38(6):2727-2734. Epub 2018 Dec 7. PMID:
30573355
Article Published Date
: Jan 12, 2019
Study Type
: Human Study
Additional Links
Substances
:
Grape
,
Polyphenols
Diseases
:
Insulin Resistance
Pharmacological Actions
:
Insulin Sensitizers
[+]
Green tea drinkers with susceptible IGF1 (CA)19/(CA)19 and (CA)19/X genotypes had a significant reduced risk of lung cancer.
Jan 01, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2012 ;7(2):e30951. Epub 2012 Feb 7. PMID:
22347413
Article Published Date
: Jan 01, 2012
Study Type
: Human Study
Additional Links
Substances
:
Green Tea
,
Polyphenols
Diseases
:
Lung Cancer: Prevention
Pharmacological Actions
:
Antiproliferative
,
Chemopreventive
Additional Keywords
:
Risk Reduction
Problem Substances
:
Tobacco: Smoking
[+]
Green tea drinking suppresses proliferation of HTLV-1-infected lymphocytes in vivo.
Jul 01, 2004
Click here to read the entire abstract
Pubmed Data
: Cancer Sci. 2004 Jul;95(7):596-601. PMID:
15245597
Article Published Date
: Jul 01, 2004
Study Type
: Human Study
Additional Links
Substances
:
Green Tea
,
Polyphenols
Diseases
:
Adult T-cell leukemia/lymphoma (ATL)
,
Human T-Cell Lymphotrophic Virus type 1 associated disease
Pharmacological Actions
:
Antiviral Agents
[+]
Green tea extract decreased fasting insulin concentrations in those with elevated baseline fasting concentrations.
Jan 01, 2016
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2016 Jan ;146(1):38-45. Epub 2015 Nov 18. PMID:
26581683
Article Published Date
: Jan 01, 2016
Study Type
: Human Study
Additional Links
Substances
:
Catechin
,
Polyphenols
,
Tea
Diseases
:
Adiponectin: Low Levels
,
Obesity
Therapeutic Actions
:
Fasting/Caloric Restriction
Additional Keywords
:
Plant Extracts
Problem Substances
:
Insulin
[+]
Green tea induced changes in NFκB and systemic oxidation, and uptake of GT polyphenols in prostate tissue they may have a role in prostate cancer prevention and treatment.
Mar 31, 2015
Click here to read the entire abstract
Pubmed Data
: Prostate. 2015 Apr 1 ;75(5):550-9. Epub 2014 Dec 24. PMID:
25545744
Article Published Date
: Mar 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Black Tea
,
Green Tea
,
Polyphenols
Diseases
:
Prostate Cancer
,
Prostate Cancer: Prevention
Pharmacological Actions
:
Chemopreventive
,
NF-kappaB Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Green tea polyphenol treatment could have potential beneficial effects on LDL-cholesterol concentrations.
Jun 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Acta Cardiol Sin. 2016 Jul ;32(4):439-49. PMID:
27471357
Article Published Date
: Jun 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Green Tea
,
Polyphenols
Diseases
:
Angina Pectoris
Pharmacological Actions
:
Anticholesteremic Agents
Additional Keywords
:
Dietary Concentrations
[+]
H. sabdariffa extract improved metabolism, displayed potent anti-inflammatory and antioxidant activities, and significantly reduced blood pressure.
May 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Nutr Food Res. 2014 Jun ;58(6):1374-8. Epub 2014 Feb 24. PMID:
24668839
Article Published Date
: May 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Hibiscus sabdariffa
,
Polyphenols
Diseases
:
Cardiovascular Diseases
,
Endothelial Dysfunction
,
Hypertension
,
Metabolic Diseases
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antihypertensive Agents
,
Antioxidants
Additional Keywords
:
Plant Extracts
,
Significant Treatment Outcome
[+]
Hibiscus and lemon verbena polyphenols modulate appetite-related biomarkers in overweight subjects.
Jun 19, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Funct. 2018 Jun 20 ;9(6):3173-3184. PMID:
29862395
Article Published Date
: Jun 19, 2018
Study Type
: Human Study
Additional Links
Substances
:
Hibiscus sabdariffa
,
Lemon Verbena
,
Polyphenols
Diseases
:
Obesity
,
Overweight
Pharmacological Actions
:
Hypolipidemic
Additional Keywords
:
Anti-Obesity Agents
,
Plant Extracts
[+]
Hibiscus sabdariffa exerts beneficial effects on inflammation, endothelial dysfunction, and oxidation, systemically inhibits the renin-angiotensin system and angiotensin-converting enzyme.
Sep 01, 2015
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2015 Sep ;6(9):2957-66. PMID:
26234931
Article Published Date
: Sep 01, 2015
Study Type
: Human Study
Additional Links
Substances
:
Hibiscus sabdariffa
,
Polyphenols
Diseases
:
Hypertension
Pharmacological Actions
:
Angiotensin-Converting Enzyme Inhibitors
Additional Keywords
:
Plant Extracts
[+]
High concentrations of polyphenols, a nutritional biomarker of polyphenol intake, were associated with lower risk of substantial cognitive decline in an older population studied over a 3-year period.
Apr 30, 2015
Click here to read the entire abstract
Pubmed Data
: J Am Geriatr Soc. 2015 May ;63(5):938-46. Epub 2015 Apr 27. PMID:
25919574
Article Published Date
: Apr 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
Diseases
:
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Risk Factors
,
Risk Reduction
[+]
High dietary intake of polyphenols may be associated with longevity.
Aug 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Nutr. 2013 Sep ;143(9):1445-50. Epub 2013 Jun 26. PMID:
23803472
Article Published Date
: Aug 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
Diseases
:
All-Cause Mortality
[+]
High levels of Bifidobacteria are associated with increased levels of anthocyanin microbial metabolites.
Jul 31, 2014
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2014 Aug ;5(8):1932-8. PMID:
24958563
Article Published Date
: Jul 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Polyphenols
Diseases
:
Dysbiosis: Bifidobacteria Deficiency
Additional Keywords
:
Metabolites
,
Microbiota
[+]
Increases in dietary polyphenols are associated with decreased inflammatory biomarkers.
Apr 20, 2016
Click here to read the entire abstract
Pubmed Data
: Br J Clin Pharmacol. 2016 Apr 21. Epub 2016 Apr 21. PMID:
27100393
Article Published Date
: Apr 20, 2016
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
Diseases
:
Cardiovascular Diseases
,
Hypertension
,
Inflammation
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antihypertensive Agents
Additional Keywords
:
Dose Response
,
Risk Reduction
[+]
Intake of total polyphenols and some classes of polyphenols is inversely associated with diabetes in elderly People at high cardiovascular disease risk.
Mar 08, 2016
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2016 Mar 9. Epub 2016 Mar 9. PMID:
26962181
Article Published Date
: Mar 08, 2016
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cardiovascular Disease: Prevention
,
Diabetes Mellitus: Type 2: Prevention
Additional Keywords
:
Risk Reduction
[+]
Long-term green tea polyphenol supplementation could be an efficient protection against the health issues induced by high-voltage power lines.
Aug 31, 2016
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol Pharmacol. 2016 Sep ;46:183-7. Epub 2016 Jul 26. PMID:
27490209
Article Published Date
: Aug 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Green Tea
,
Polyphenols
Diseases
:
Oxidative Stress
Additional Keywords
:
Risk Reduction
Anti Therapeutic Actions
:
Electromagnetic Field Harms
[+]
Medium-term administration of onion peel extract an improvement in flow-mediated dilation and circulating endothelial progenitor cells.
Aug 31, 2015
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2015 Sep ;31(9):1131-5. PMID:
26233871
Article Published Date
: Aug 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Onion
,
Polyphenols
,
Quercetin
Diseases
:
Cardiovascular Diseases
,
Endothelial Dysfunction
,
Obesity
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Modulation of aflatoxin biomarkers in human blood and urine by green tea polyphenols intervention.
Jan 31, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Carcinogenesis. 2008 Feb ;29(2):411-7. Epub 2008 Jan 12. PMID:
18192689
Article Published Date
: Jan 31, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Tea
Diseases
:
Aflatoxicosis
,
Liver Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
Problem Substances
:
Aflatoxin
[+]
Natural ice cream rich in polyphenols improved vascular function and physical performance in healthy people through a reduction in oxidative stress.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2017 Jan ;33:225-233. Epub 2016 Jul 26. PMID:
27658659
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
Diseases
:
Endothelial Dysfunction
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
Nutritional doses of grape polyphenols protects against fructose induced oxidative stress and insulin resistance.
May 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Diabetes Care. 2013 Jun ;36(6):1454-61. Epub 2012 Dec 28. PMID:
23275372
Article Published Date
: May 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Grape
,
Polyphenols
Diseases
:
Diabetes Mellitus: Type 2
,
Insulin Resistance
,
Metabolic Diseases
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
High-fructose Corn Syrup
[+]
Olive (Olea europaea L.) leaf polyphenols improve insulin sensitivity in middle-aged overweight men.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Article Published Date
: Dec 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Olive leaf extract
,
Polyphenols
Diseases
:
Diabetes Mellitus: Type 2
,
Insulin Resistance
Pharmacological Actions
:
Insulin Sensitizers
Additional Keywords
:
Plant Extracts
[+]
Participants with high intake of chocolate products and cocoa-derived flavanols experience a reduced risk of developing T2D.
May 23, 2018
Click here to read the entire abstract
Pubmed Data
: Eur J Clin Nutr. 2018 May 24. Epub 2018 May 24. PMID:
29795238
Article Published Date
: May 23, 2018
Study Type
: Human Study
Additional Links
Substances
:
Cocoa
,
Polyphenols
Diseases
:
Diabetes Mellitus: Type 2
[+]
Plasma antioxidant capacity can be increased by long-term ingestion of polyphenols from fruit juices or fruit-vegetable-concentrate in HIV-seropositive patients.
Oct 01, 2000
Click here to read the entire abstract
Pubmed Data
: Toxicol In Vitro. 2000 Oct;14(5):405-8. PMID:
11528495
Article Published Date
: Oct 01, 2000
Study Type
: Human Study
Additional Links
Substances
:
Antioxidant formulas
,
Fruit: All
,
Polyphenols
,
Vegetables: All
Diseases
:
HIV Infections
Pharmacological Actions
:
Antioxidants
[+]
Polyphenol and methylsulfonylmethane supplementation improves immune, DAMP signaling, and inflammatory responses during recovery from all-out running efforts.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Physiol. 2021 ;12:712731. Epub 2021 Aug 31. PMID:
34531760
Article Published Date
: Dec 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
,
MSM (Methylsulfonylmethane)
,
Polyphenols
,
Pomegranate Polyphenols
Diseases
:
Inflammation
Therapeutic Actions
:
Exercise: Running
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Polyphenol rich berry juices reduce blood pressure in hypertensive patients more so than in normotensive subjects.
Oct 13, 2015
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2015 Oct 14 ;114(7):1054-63. Epub 2015 Jul 31. PMID:
26227795
Article Published Date
: Oct 13, 2015
Study Type
: Human Study
Additional Links
Substances
:
Bilberry
,
Cherry: All Varieties
,
Chokeberry
,
Grape
,
Polyphenols
Diseases
:
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
,
Antioxidants
[+]
Polyphenols from strawberries and cranberries improved insulin sensitivity in overweight and obese non-diabetic, insulin-resistant human subjects.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2017 Feb ;117(4):519-531. Epub 2017 Mar 14. PMID:
28290272
Article Published Date
: Jan 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Cranberry
,
Polyphenols
,
Strawberry
Diseases
:
Insulin Resistance
,
Obesity
Pharmacological Actions
:
Insulin Sensitizers
[+]
Pomegranate juice consumption appears to slow the progression of the carotid intima-media thickness in subjects with increased oxidative stress and poor blood lipid profiles.
Oct 01, 2009
Click here to read the entire abstract
Pubmed Data
: Am J Cardiol. 2009 Oct 1;104(7):936-42. PMID:
19766760
Article Published Date
: Oct 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
,
Pomegranate
Diseases
:
Arterial Thickening
,
Carotid Artery Narrowing
,
Intima Media Thickening
Pharmacological Actions
:
Anti-atherogenic
,
Antioxidants
[+]
Propolis has radioprotective properties.
Aug 01, 2009
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2009 Aug;23(8):1159-68. PMID:
19165751
Article Published Date
: Aug 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Bee Propolis
,
Flavonoids
,
Polyphenols
Diseases
:
DNA damage
,
Radiation Induced Illness
Pharmacological Actions
:
Radioprotective
[+]
Raspberries lower postprandial hyperglycemia and inflammation.
Jan 01, 2019
Click here to read the entire abstract
Pubmed Data
: Ann Nutr Metab. 2019 ;74(2):165-174. Epub 2019 Feb 14. PMID:
30763939
Article Published Date
: Jan 01, 2019
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
,
Raspberry
Diseases
:
Diabetes Mellitus: Type 2
,
Hyperglycemia
,
Inflammation
Pharmacological Actions
:
Antioxidant
[+]
Red grape polyphenol oral administration improves immune response in women affected by nickel-mediated allergic contact dermatitis.
Jan 12, 2020
Click here to read the entire abstract
Pubmed Data
: Endocr Metab Immune Disord Drug Targets. 2020 03 13. Epub 2020 Mar 13. PMID:
32167433
Article Published Date
: Jan 12, 2020
Study Type
: Human Study
Additional Links
Substances
:
Grape
,
Polyphenols
Diseases
:
Dermatitis: Contact
Pharmacological Actions
:
Immunomodulatory
[+]
Red wine polyphenols can inhibit non beneficial bacteria from the human microbiota and potentiate the growth of probiotic bacteria such as bifidobacteria.
May 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Clin Nutr. 2012 Jun ;95(6):1323-34. Epub 2012 May 2. PMID:
22552027
Article Published Date
: May 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
,
Red Wine Extract
Diseases
:
C-Reactive Protein
,
Dysbiosis
,
Dysbiosis: Bifidobacteria Deficiency
,
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
,
Gastrointestinal Agents
,
Hypolipidemic
Additional Keywords
:
Significant Treatment Outcome
[+]
Regular moderate intake of red wine is linked to a better women's sexual health.
Sep 30, 2009
Click here to read the entire abstract
Pubmed Data
: J Sex Med. 2009 Oct ;6(10):2772-7. Epub 2009 Jul 21. PMID:
19627470
Article Published Date
: Sep 30, 2009
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Wine
Diseases
:
Endothelial Dysfunction
,
Libido: Low
,
Sexaul Dysfunction
[+]
Results indicate a positive impact of regular chokeberry juice consumption on BP and lipid status in pharmacologically untreated hypertensive subjects.
May 13, 2015
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2015 May 14. Epub 2015 May 14. PMID:
25973889
Article Published Date
: May 13, 2015
Study Type
: Human Study
Additional Links
Substances
:
Chokeberry
,
Polyphenols
Diseases
:
Blood Pressure: High
,
Cardiovascular Diseases
,
Hypertension
,
Triglycerides: Elevated
Pharmacological Actions
:
Antihypertensive Agents
,
Cardioprotective
,
Hypolipidemic
Additional Keywords
:
Dietary Modification
,
Significant Treatment Outcome
[+]
Rooibos tea improves the lipid profile and redox status of adults at risk of developing cardiovascular disease.
Jan 07, 2011
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2011 Jan 7 ;133(1):46-52. Epub 2010 Sep 15. PMID:
20833235
Article Published Date
: Jan 07, 2011
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Rooibos
Diseases
:
Cardiovascular Diseases
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Short-term cocoa consumption signficantly reduces blood cholesterol.
Jul 01, 2010
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2010 Jul;92(1):218-25. Epub 2010 May 26. PMID:
20504978
Article Published Date
: Jul 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cardiovascular Diseases
,
High Cholesterol
Pharmacological Actions
:
Anticholesteremic Agents
[+]
Short-term supplementation with curcumin improves liver fat and transaminase levels in patients with NAFLD.
Mar 31, 2017
Click here to read the entire abstract
Pubmed Data
: Drug Res (Stuttg). 2017 Apr ;67(4):244-251. Epub 2017 Feb 3. PMID:
28158893
Article Published Date
: Mar 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
,
Polyphenols
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Significant decreases in bowel movement frequency and rapid normalization of stool consistency were observed with consumption of this novel solution.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PeerJ. 2015 ;3:e969. Epub 2015 May 21. PMID:
26038724
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
Diseases
:
Diarrhea
,
Diarrhea: in Children
Pharmacological Actions
:
Antidiarrheals
,
Gastrointestinal Agents
Additional Keywords
:
Significant Treatment Outcome
[+]
Supplementation with 150 mg/day Oligopin® for 12 weeks exerts beneficial effects in postmenopausal osteopenia.
Dec 31, 2020
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2021 Jan ;81:153417. Epub 2020 Nov 19. PMID:
33250314
Article Published Date
: Dec 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
Diseases
:
Osteopenia
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
Supplementation with green tea extract prevents exercise-induced oxidative stress.
Aug 01, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Eur J Nutr. 2015 Aug ;54(5):783-91. Epub 2014 Aug 14. PMID:
25120110
Article Published Date
: Aug 01, 2015
Study Type
: Human Study
Additional Links
Substances
:
Green Tea
,
Polyphenols
,
Tea
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Supplementation with red wine extract increases insulin sensitivity and peripheral blood mononuclear Sirt1 expression in nondiabetic humans.
Oct 11, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2020 Oct 12 ;12(10). Epub 2020 Oct 12. PMID:
33053742
Article Published Date
: Oct 11, 2020
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
,
Red Wine Extract
,
Resveratrol
Diseases
:
Insulin Resistance
Pharmacological Actions
:
Hypolipidemic
,
Interleukin-6 Downregulation
[+]
Tea consumption reduces the risk of biliary tract and gallbladder diseases.
Nov 01, 2005
Click here to read the entire abstract
Pubmed Data
: Zhonghua Zhong Liu Za Zhi. 2005 Nov;27(11):667-71. PMID:
16438888
Article Published Date
: Nov 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Green Tea
,
Polyphenols
,
Tea: Black
Diseases
:
Bile Duct Cancer
,
Gallbladder Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Tea polyphenols (primarily EGCG), significantly reduce PSA, Hepatocyte growth factor, VEG in men with prostate cancer.
Jul 01, 2009
Click here to read the entire abstract
Pubmed Data
: Cancer Prev Res (Phila Pa). 2009 Jul;2(7):673-82. Epub 2009 Jun 19. PMID:
19542190
Article Published Date
: Jul 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
,
Green Tea
,
Polyphenols
Diseases
:
Prostate: PSA Doubling
,
Prostate Cancer
Pharmacological Actions
:
Hepatocyte growth factor (HGF) inhibitor
,
Vascular Endothelial Growth Factor Regulator
[+]
The association between common foods, such as oranges and apples, with specific microorganisms reported to be decreased in SLE could be of great importance for these patients.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2015 ;7(2):1301-17. Epub 2015 Feb 16. PMID:
25690419
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Apples
,
Oranges
,
Polyphenols
,
Red Wine Extract
Diseases
:
Dysbiosis
,
Systemic Lupus Erythematosus
Pharmacological Actions
:
Gastrointestinal Agents
Additional Keywords
:
Microbiota
[+]
The intake of flavonoids showed an inverse association with risk of cardiovascular events.
Oct 03, 2018
Click here to read the entire abstract
Pubmed Data
: Nutr Metab Cardiovasc Dis. 2018 Oct 4. Epub 2018 Oct 4. PMID:
30459074
Article Published Date
: Oct 03, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cardiovascular Diseases
Additional Keywords
:
Risk Reduction
[+]
The Mediterranean diet, which includes a combination of antioxidant compounds and flavonoid-rich foods, appears effective to decrease LDL particle oxidizability, which reduces the risk for cardiovascular disease.
Oct 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2006 Oct;17(10):645-58. Epub 2006 Feb 3. PMID:
16517144
Article Published Date
: Oct 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Arteriosclerosis
,
Cardiovascular Diseases
,
Cholesterol: Oxidation
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet
Pharmacological Actions
:
Antioxidants
[+]
There is a synergistic interplay between curcumin and polyphenol-rich foods in the Mediterranean diet.
Jul 20, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Jul 21 ;9(7). Epub 2017 Jul 21. PMID:
28754004
Article Published Date
: Jul 20, 2017
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
,
Polyphenols
Diseases
:
Neurofibromatosis
Therapeutic Actions
:
Mediterranean diet
Additional Keywords
:
Natural Substance Synergy
,
Significant Treatment Outcome
[+]
These results provide for the first time a first-level evidence of an enhancement in HDL function by polyphenol-rich olive oil.
Aug 31, 2014
Click here to read the entire abstract
Pubmed Data
: Arterioscler Thromb Vasc Biol. 2014 Sep ;34(9):2115-9. Epub 2014 Jul 24. PMID:
25060792
Article Published Date
: Aug 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Olive Oil
,
Polyphenols
Diseases
:
Cholesterol: Oxidation
,
HDL: Low
Pharmacological Actions
:
Antioxidants
[+]
These results suggest that combined administration of black soybean with fenofibrate enhances the antihyperlipidemic action of fenofibrate.
Jun 01, 2015
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2015 Jun ;18(6):615-8. Epub 2015 Feb 4. PMID:
25651043
Article Published Date
: Jun 01, 2015
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
,
Soy
Diseases
:
Diabetes Mellitus: Type 2
,
Hyperlipidemia
Additional Keywords
:
Drug Synergy
,
Phytotherapy
,
Plant Extracts
[+]
This pilot study provides the first evidence of miRNA modulation by diet and other factors, that can be detected consistently in both plasma and stools samples.
Aug 31, 2014
Click here to read the entire abstract
Pubmed Data
: Mutagenesis. 2014 Sep ;29(5):385-91. PMID:
25150024
Article Published Date
: Aug 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Pharmacological Actions
:
MicroRNA modulator
Additional Keywords
:
Dietary Concentrations
,
Epigenetic Modification
[+]
This study provides clinical information concerning the use of Aliva, a novel polyphenol-based prebiotic for the treatment of acute nonspecific diarrhea in children and adults.
Sep 13, 2014
Click here to read the entire abstract
Article Publish Status
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Pubmed Data
: World J Gastroenterol. 2014 Sep 14 ;20(34):12301-7. PMID:
25232265
Article Published Date
: Sep 13, 2014
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
,
Prebiotics
Diseases
:
Diarrhea
,
Gastroenteritis
,
Rotavirus Infections
Pharmacological Actions
:
Gastrointestinal Agents
Additional Keywords
:
Significant Treatment Outcome
[+]
This study shows direct and indirect associations with lipid molecular species and clinical variables of interest in the evaluation of the metabolic syndrome after diets naturally rich in polyphenols.
Aug 31, 2014
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2014 Sep ;58(9):1873-82. Epub 2014 Jun 24. PMID:
24961394
Article Published Date
: Aug 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Omega-3 Fatty Acids
,
Polyphenols
Diseases
:
Cardiovascular Diseases
,
Metabolic Diseases
,
Obesity: Abdominal
Additional Keywords
:
Dietary Modification
[+]
Usefulness of extra virgin olive oil minor polar compounds in the management of chronic kidney disease patients.
Feb 09, 2021
Click here to read the entire abstract
Article Publish Status
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Pubmed Data
: Nutrients. 2021 Feb 10 ;13(2). Epub 2021 Feb 10. PMID:
33578682
Article Published Date
: Feb 09, 2021
Study Type
: Human Study
Additional Links
Substances
:
Olive
,
Polyphenols
Diseases
:
Chronic Kidney Disease (CKD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Whey protein, omega-3 fatty acids and polyphenols with electrical muscle stimulation increases muscle strength in elderly adults with limited mobility.
Jun 22, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Nutrients. 2020 Jun 23 ;12(6). Epub 2020 Jun 23. PMID:
32585837
Article Published Date
: Jun 22, 2020
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
,
Omega-3 Fatty Acids
,
Polyphenols
,
Rutin
,
Whey
Diseases
:
Sarcopenia
Therapeutic Actions
:
Electric Stimulation
[+]
Wine consumption reduces TNF-apha-induced adhesion of monocytes to endothelial cells.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Cell Physiol Biochem. 2010;26(3):471-82. Epub 2010 Aug 24. PMID:
15213052
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Wine
Diseases
:
Arteriosclerosis
,
Heart Disease: Ischemic
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
1,3,4-tri-O-galloyl-6-O-caffeoyl-β-D-glucopyranose, a New Anti-Proliferative Ellagitannin, Regulates the Expression of microRNAs in HepG(2) Cancer Cells.
Oct 01, 2011
Click here to read the entire abstract
Pubmed Data
: Nan Fang Yi Ke Da Xue Xue Bao. 2011 Oct ;31(10):1641-8. PMID:
22027761
Article Published Date
: Oct 01, 2011
Study Type
: Human In Vitro
Additional Links
Substances
:
Polyphenols
,
Tannic Acid
Diseases
:
Cancers
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
[+]
chokeberry juice inhibited Caco-2 cell proliferation by causing G(2)/M cell cycle arrest.
Mar 31, 2007
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2007 Apr ;18(4):259-71. Epub 2006 Jul 24. PMID:
16860979
Article Published Date
: Mar 31, 2007
Study Type
: Human In Vitro
Additional Links
Substances
:
Chokeberry
,
Flavonoids
,
Polyphenols
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
Pharmacological Actions
:
Antiproliferative
,
Cell cycle arrest
,
Chemopreventive
[+]
Chokeberry, bilberry, raspberry, and cranberry extract increases adiponectin, decreases leptin, and suppresses adipogenesis/lipogenesis in vitro.
Jan 01, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: PLoS One. 2017 ;12(11):e0188583. Epub 2017 Nov 28. PMID:
29182628
Article Published Date
: Jan 01, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Polyphenols
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidant Effects
Additional Keywords
:
Plant Extracts
[+]
Cultured coconut extract showed a barrier-enhancing effect and anti-inflammatory properties against UVB irradiation-induced inflammation.
Jul 31, 2017
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2017 Aug ;106(Pt A):367-375. Epub 2017 May 28. PMID:
28564614
Article Published Date
: Jul 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Coconut
,
Polyphenols
Diseases
:
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Photoprotective
Additional Keywords
:
Plant Extracts
[+]
Depsidic gallotannins and simpler galloylated glucose derivatives all inhibit amyloid β-peptide (Aβ) aggregation in vitro, and monogalloylated α-glucogallin and a natural β-hexagalloylglucose are shown to be the strongest inhibitors.
Jul 06, 2015
Click here to read the entire abstract
Pubmed Data
: Angew Chem Int Ed Engl. 2015 Jul 6 ;54(28):8217-21. Epub 2015 May 26. PMID:
26013280
Article Published Date
: Jul 06, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Polyphenols
,
Tannic Acid
Pharmacological Actions
:
Neuroprotective Agents
[+]
Dietary coffee polyphenols augment gut-derived active GLP-1 secretion via the cAMP-dependent pathway, which may contribute to the reduced risk of type 2 diabetes.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Nutr Sci. 2015 ;4:e9. Epub 2015 Mar 3. PMID:
26097706
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Coffee
,
Polyphenols
Diseases
:
Diabetes Mellitus: Type 2: Prevention
Pharmacological Actions
:
Glucagon Like peptide 1 (GLP-1) Up-regulation
Additional Keywords
:
Risk Reduction
[+]
Fermentable carbohydrates and polyphenols inhibit trimethylamine production in the colon.
Dec 13, 2018
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2018 Dec 13 ;9(12):6470-6483. PMID:
30465688
Article Published Date
: Dec 13, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Polyphenols
,
Prebiotics
Diseases
:
Cardiovascular Disease
[+]
Plant polyphenols mitigate the pro-inflammatory and pro-oxidant adipocyte response to lipopolysaccharides.
Jan 01, 2017
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2017 05 ;119:303-312. Epub 2017 Feb 27. PMID:
28249816
Article Published Date
: Jan 01, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Polyphenols
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Polyphenol antioxidant treatment may provide an adjunctive action to alleviate pulmonary vascular remodeling.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Biol Sci. 2017 ;13(8):1067-1081. Epub 2017 Sep 3. PMID:
28924387
Article Published Date
: Dec 31, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Polyphenols
Diseases
:
Hypertension: Pulmonary
Pharmacological Actions
:
Antihypertensive Agents
,
Antioxidants
,
Nrf2 activation
[+]
Polyphenol interactions mitigate the immunogenicity and allergenicity of gliadins.
Feb 12, 2017
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2017 Feb 13. Epub 2017 Feb 13. PMID:
28190352
Article Published Date
: Feb 12, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Apple Polyphenols
,
Artichoke
,
Cranberry
,
Green Tea
,
Polyphenols
Diseases
:
Anti-gliadin Antibodies: Elevated
,
Food Allergies: Wheat
Pharmacological Actions
:
Anti-Allergic Agents
Additional Keywords
:
Plant Extracts
[+]
Polyphenols may modulate intestinal lipid absorption through effects on intestinal glucose uptake.
Jun 19, 2019
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2019 Jun 19 ;10(6):3127-3134. PMID:
31140506
Article Published Date
: Jun 19, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Polyphenols
Diseases
:
Hyperlipidemia
Pharmacological Actions
:
Anticholesteremic Agents
,
Antilipemic Agents
[+]
Red grape are a source of compounds that ameliorate endothelial progenitor cells viability and function, while preventing endothelial dysfunction.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Eur J Pharm Biopharm. 2012 Jan ;80(1):176-84. Epub 2011 Sep 24. PMID:
21971368
Article Published Date
: Dec 31, 2011
Study Type
: Human In Vitro
Additional Links
Substances
:
Grape
,
Polyphenols
Diseases
:
Atherosclerosis
,
Endothelial Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Gastrointestinal Agents
Additional Keywords
:
Plant Extracts
[+]
Tea polyphenols act as renin inhibitors and may control hypertension.
Oct 09, 2013
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2013 Oct 9 ;61(40):9697-704. Epub 2013 Sep 30. PMID:
24028635
Article Published Date
: Oct 09, 2013
Study Type
: Human In Vitro
Additional Links
Substances
:
Catechin
,
Polyphenols
,
Tea
Diseases
:
Hypertension
Additional Keywords
:
Plant Extracts
[+]
VEGF is a key molecular target for specific polyphenols found in tea, apples and cocoa which potently inhibit VEGF signalling and angiogenesis at physiological concentrations.
Feb 28, 2015
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2015 Mar ;59(3):401-12. Epub 2015 Jan 22. PMID:
25546248
Article Published Date
: Feb 28, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Apple Polyphenols
,
EGCG (Epigallocatechin gallate)
,
Polyphenols
Diseases
:
Cancers: All
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Diet
[+]
Whey protein and high polyphenolic cocoa increase adiponectin levels and result in a lower glucose response compared to that of a low polyphenolic cocoa.
Mar 01, 2016
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2016 Mar ;19(3):219-27. PMID:
26987021
Article Published Date
: Mar 01, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Polyphenols
,
Whey
Diseases
:
Hyperglycemia
Pharmacological Actions
:
Adiponectin upregulation
,
Hypoglycemic Agents
[+]
Zingerone could be a potential therapeutic agent for treatment of various severe vascular inflammatory diseases.
Feb 28, 2018
Click here to read the entire abstract
Pubmed Data
: Arch Pharm Res. 2018 Mar ;41(3):276-287. Epub 2017 May 16. PMID:
28508944
Article Published Date
: Feb 28, 2018
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Ginger
,
Polyphenols
Diseases
:
Inflammation
,
Sepsis
Pharmacological Actions
:
Cytoprotective
[+]
Purple grape juices prevent pentylenetetrazol-induced oxidative damage in the liver and serum of Wistar rats.
Jan 31, 2013
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2013 Feb ;33(2):120-5. Epub 2013 Jan 17. PMID:
23399662
Article Published Date
: Jan 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Grape
,
Polyphenols
Diseases
:
Lipid Peroxidation
,
Liver Damage: Drug-Induced
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
[+]
"Polyphenols decreased liver NADPH oxidase activity, increased muscle mitochondrial biogenesis and decreased gastrocnemius age-dependent autophagy in aged rats."
May 18, 2012
Click here to read the entire abstract
Pubmed Data
: Free Radic Res. 2012 May 18. Epub 2012 May 18. PMID:
22607117
Article Published Date
: May 18, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Grape
,
Polyphenols
Additional Keywords
:
Mitochondrial Biogenesis
[+]
A cocoa diet enhances thymus antioxidant defenses and influences thymocyte differentiation.
Aug 08, 2007
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2007 Aug 8;55(16):6431-8. Epub 2007 Jul 14. PMID:
17630760
Article Published Date
: Aug 08, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Catechin
,
Flavonoids
,
Polyphenols
Diseases
:
Low Immune Function: Thymus Dysfunction
Pharmacological Actions
:
Antioxidants
,
Immunomodulatory
[+]
A cocoa enriched diet produces an immunomodulatory effect that prevents anti-allergen IgE synthesis.
May 31, 2012
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2012 Jun ;65(6):603-8. Epub 2012 Feb 10. PMID:
22342543
Article Published Date
: May 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Polyphenols
Diseases
:
Allergies
,
Hypersensitivity
Pharmacological Actions
:
Anti-Allergic Agents
,
Immunomodulatory
,
Interleukin-10 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Dietary Flavanoid
[+]
A cocoa polyphenol-rich extract increases the chronological lifespan of S. cerevisiae.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Frailty Aging. 2016 ;5(3):186-90. PMID:
27554321
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Cocoa
,
Polyphenols
Diseases
:
Aging
Pharmacological Actions
:
Antioxidants
[+]
A cocoa-enriched diet prevents gingival oxidative stress in experimental periodontitis.
Nov 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Periodontol. 2009 Nov;80(11):1799-808. PMID:
19905949
Article Published Date
: Nov 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Cocoa
,
Flavonoids
,
Polyphenols
Diseases
:
Periodontitis
Pharmacological Actions
:
Antioxidants
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A combination of pomegranate, date fruit and date seeds led to a more potent treatment result than each alone.
Mar 25, 2015
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2015 Mar 26. Epub 2015 Mar 26. PMID:
25811166
Article Published Date
: Mar 25, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Dates
,
Polyphenols
,
Pomegranate
Diseases
:
Atherosclerosis
,
Oxidative Stress
,
Triglycerides: Elevated
Pharmacological Actions
:
Anti-atherogenic
,
Anticholesteremic Agents
,
Antioxidants
Additional Keywords
:
Natural Substance Synergy
[+]
A matured fruit extract of date palm tree (Phoenix dactylifera L.) stimulates the cellular immune system in mice.
Oct 25, 2011
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2011 Oct 26 ;59(20):11287-93. Epub 2011 Oct 3. PMID:
21936496
Article Published Date
: Oct 25, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Dates
,
Polyphenols
Diseases
:
Immune Disorders: Low Immune Function
Pharmacological Actions
:
Immunomodulatory
Additional Keywords
:
Plant Extracts
[+]
A polyphenol extract from red grapes redues fat content in an animal model of non-alcoholic liver disease.
Dec 01, 2010
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2010 Dec;104(12):1760-70. Epub 2010 Aug 2. PMID:
20673376
Article Published Date
: Dec 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Grape
,
Polyphenols
,
Resveratrol
Diseases
:
Fatty Liver
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
A polyphenol-rich strawberry extract exerts important biological activities against a highly invasive breast cancer cell line.
Aug 07, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2016 Aug 8 ;6:30917. Epub 2016 Aug 8. PMID:
27498973
Article Published Date
: Aug 07, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Polyphenols
,
Strawberry
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Cell cycle arrest
,
Chemopreventive
Additional Keywords
:
Dose Response
[+]
Administration of a polyphenol-rich apple extract reduces the number of neoplastic lesions in mice with AOM-induced colorectal cancer.
Apr 14, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Foods. 2021 Apr 15 ;10(4). Epub 2021 Apr 15. PMID:
33921048
Article Published Date
: Apr 14, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Apple
,
Polyphenols
Diseases
:
Cachexia
,
Colorectal Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
Allomelanins suppress the tumor cell growth in vitro and in vivo.
Aug 01, 1997
Click here to read the entire abstract
Pubmed Data
: Cancer Biother Radiopharm. 1997 Aug;12(4):273-6. PMID:
10851475
Article Published Date
: Aug 01, 1997
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Lymphoma
Pharmacological Actions
:
Cell cycle arrest
Additional Keywords
:
Food Colors: Black
,
Food Colors: Purple
[+]
Ameliorative effect of Ecklonia cava polyphenol extract on renal inflammation.
May 16, 2017
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2017 May 17 ;65(19):3811-3818. Epub 2017 May 5. PMID:
28459555
Article Published Date
: May 16, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Polyphenols
,
Seaweed: Brown
Diseases
:
Kidney Damage
,
Obesity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Nrf2 activation
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
An antioxidant-rich extract of seaweed polyphenols combined with current PC treatment modalities may inhibit tumor relapse by targeting therapy-orchestrated autophagy in residual cells.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Biomed Sci. 2015 ;22(1):28. Epub 2015 Apr 17. PMID:
25898131
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Polyphenols
,
Seaweed
Diseases
:
Cancers: Drug Resistant
,
Cancers: Radiation-Resistant
,
Pancreatic Cancer
Pharmacological Actions
:
Antiproliferative
,
Autophagy Inhibitors
,
Chemotherapeutic
Additional Keywords
:
Chemotherapeutic Synergy: Gemcitabine
,
Gene Expression Regulation
,
Significant Treatment Outcome
[+]
An apple peel polyphenol extract protected cells against the indomethacin-associated adverse effects in vivo.
Nov 08, 2011
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2011 Nov 9 ;59(21):11501-8. Epub 2011 Oct 6. PMID:
21954913
Article Published Date
: Nov 08, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Apple
,
Polyphenols
Diseases
:
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Cytoprotective
Additional Keywords
:
Drug: Indomethacin
Problem Substances
:
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]
An aqueous decoction of mango flowers has potential gastroprotective and ulcer-healing properties.
Aug 01, 2004
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2004 Aug;70(8):745-52. PMID:
16500058
Article Published Date
: Aug 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Flowers
,
Mango
,
Polyphenols
Diseases
:
Gastric Ulcer
Pharmacological Actions
:
Anti-Ulcer Agents
,
Cyclooxygenase Inhibitors
Additional Keywords
:
Plant Extracts
[+]
An Ayurvedic formulation of Emblica officinalis and Curcuma longa alleviates insulin resistance in diabetic rats.
Aug 06, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ayurveda Integr Med. 2021 Aug 7. Epub 2021 Aug 7. PMID:
34376352
Article Published Date
: Aug 06, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Amla Fruit
,
Curcuminoids
,
Polyphenols
,
Turmeric
Diseases
:
Diabetes Mellitus: Type 2
,
Insulin Resistance
Pharmacological Actions
:
Hypoglycemic Agents
[+]
An extract of aged black garlic significantly suppressed IgE-induced anaphylaxis in a (PCA) model.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Med Food. 2014 Jan ;17(1):92-102. PMID:
24456359
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Garlic: Aged
,
Polyphenols
Diseases
:
Allergies
,
Anaphylaxis
,
IgE-Mediated Hypersensitivity
Pharmacological Actions
:
Anti-Allergic Agents
,
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Analgesic effects and the mechanisms of anti-inflammation of hispolon in mice.
Dec 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2011 ;2011:478246. Epub 2010 Oct 25. PMID:
19349477
Article Published Date
: Dec 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Phellinus Linteus
,
Polyphenols
Diseases
:
Inflammation
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
,
Antioxidants
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-Inflammatory action of blueberry polyphenols in HIG-82 rabbit synoviocytes.
Sep 30, 2019
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2019 Oct ;22(10):1032-1040. Epub 2019 May 22. PMID:
31120380
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
,
Polyphenols
Diseases
:
Inflammation
,
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-inflammatory and anti-thrombotic effects of zingerone in a rat model of myocardial infarction.
Nov 14, 2016
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2016 Nov 15 ;791:595-602. Epub 2016 Aug 26. PMID:
27568839
Article Published Date
: Nov 14, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
,
Polyphenols
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Antimicrobial activity of red wine and oenological extracts against periodontal pathogens in a validated oral biofilm model.
Jun 20, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2019 Jun 21 ;19(1):145. Epub 2019 Jun 21. PMID:
31226983
Article Published Date
: Jun 20, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Polyphenols
,
Red Wine Extract
Diseases
:
Periodontal Diseases
Pharmacological Actions
:
Antimicrobial
Additional Keywords
:
Plant Extracts
[+]
Antiobesity effect of prebiotic polyphenol-rich grape seed flour supplemented with probiotic kefir-derived lactic acid bacteria.
Nov 27, 2018
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2018 Nov 28 ;66(47):12498-12511. Epub 2018 Nov 16. PMID:
30392364
Article Published Date
: Nov 27, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Grape
,
Kefir
,
Polyphenols
Diseases
:
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Anti-Obesity Agents
,
Plant Extracts
[+]
Antioxidant and antihyperlipidemic effects of Ajwa date (Phoenix dactylifera L.) extracts in rats fed a cholesterol-rich diet.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: J Food Biochem. 2019 08 ;43(8):e12933. Epub 2019 May 26. PMID:
31368543
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Dates
,
Polyphenols
Diseases
:
Hyperlipidemia
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Apple fibers and polyphenols may play a role in preventing atherosclerosis by decreasing uric acid plasma level.
Apr 01, 2007
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2007 Apr;14(4):280-4. Epub 2007 Feb 12. PMID:
18558693
Article Published Date
: Apr 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Apples
,
Fiber
,
Flavonoids
,
Polyphenols
Diseases
:
Atherosclerosis
,
Hyperuricemia
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Apple juice upregulates antioxidant-associated genes in the rat colon and liver, which may account for apple's anti-cancer activity.
Aug 01, 2000
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2000 Aug;21(8):1461-7. PMID:
20652274
Article Published Date
: Aug 01, 2000
Study Type
: Animal Study
Additional Links
Substances
:
Apples
,
Polyphenols
Diseases
:
Colon Cancer
,
Liver Cancer
Pharmacological Actions
:
Antioxidants
,
Chemopreventive
[+]
Apple polyphenol extracts have neuroprotective effects against Aluminum induced biotoxicity.
Nov 30, 2014
Click here to read the entire abstract
Pubmed Data
: Neurotoxicology. 2014 Dec ;45:111-20. Epub 2014 Oct 17. PMID:
25445564
Article Published Date
: Nov 30, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Apple Polyphenols
,
Polyphenols
Diseases
:
Aluminum Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Chelating Agents
,
Neuroprotective Agents
Additional Keywords
:
Chelation
,
Plant Extracts
[+]
Apple polyphenol extracts prevent damage to human gastric epithelial cells.
Jan 31, 2005
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Gut. 2005 Feb ;54(2):193-200. PMID:
15647180
Article Published Date
: Jan 31, 2005
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Drug-Induced Toxicity: Indomethacin
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Gastroprotective
Additional Keywords
:
Plant Extracts
[+]
Apple polyphenol may reduce the adverse effects of the immunization adjuvant cholera toxin.
Jul 30, 2009
Click here to read the entire abstract
Pubmed Data
: Vaccine. 2009 Jul 30;27(35):4808-17. Epub 2009 Jun 17. PMID:
19539583
Article Published Date
: Jul 30, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Apple Polyphenols
,
Apples
,
Polyphenols
Diseases
:
Cholera
,
Vaccine-induced Toxicity
Additional Keywords
:
Drug Side Effect Attenuation
[+]
Apples may exert their colon cancer protective effects through favorably altering gene patterns resulting in protection of cells against toxicological insults.
Jun 15, 2008
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2008 Jun 15;122(12):2647-55. PMID:
18351577
Article Published Date
: Jun 15, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Apples
,
Flavonoids
,
Polyphenols
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Epigenetic Modification
[+]
Apples rich polyphenols reduce colonic inflammation in rats.
Dec 01, 2009
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2009 Dec;102(11):1620-8. Epub 2009 Jul 22. PMID:
19622193
Article Published Date
: Dec 01, 2009
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Apples
,
Flavonoids
,
Polyphenols
Diseases
:
Inflammatory Bowel Diseases
,
Irritable Bowel Syndrome
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
[+]
Banana peel polyphenols exert a good preventive effect against hepatic injury.
Apr 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2016 May ;11(5):1947-1954. Epub 2016 Mar 11. PMID:
27168833
Article Published Date
: Apr 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Banana Peel
,
Polyphenols
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Malondialdehyde Down-regulation
[+]
Bergamot polyphenols boost therapeutic effects of the diet on non-alcoholic steatohepatitis induced by junk food.
Oct 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2018 Nov 1 ;10(11). Epub 2018 Nov 1. PMID:
30388763
Article Published Date
: Oct 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Bergamot orange
,
Polyphenols
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
Anti Therapeutic Actions
:
Western Diet
[+]
Bioavailability and in vivo antioxidant activity of a standardized polyphenol mixture extracted from brown propolis.
Jan 12, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2020 Jan 13 ;9(1). Epub 2020 Jan 13. PMID:
31940981
Article Published Date
: Jan 12, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Bee Propolis
,
Chrysin
,
Polyphenols
Diseases
:
Glioma
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Antiproliferative
Additional Keywords
:
Natural Substances Versus Drugs
,
Superiority of Natural Substances versus Drugs
[+]
Black tea polyphenols and polysaccharides could be used to prevent obesity.
May 09, 2016
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2016 May 10. Epub 2016 May 10. PMID:
27161951
Article Published Date
: May 09, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Black Tea
,
Polyphenols
Diseases
:
High Fat Diet
,
Obesity
Additional Keywords
:
Anti-Obesity Agents
[+]
Blackberries improve motor and cognitive performance in aged rats.
Jun 01, 2009
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2009 Jun;12(3):135-40. PMID:
19356316
Article Published Date
: Jun 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Blackberry
,
Flavonoids
,
Polyphenols
Diseases
:
Aging: Brain
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Blueberry inhibits the growth and metastatic potential of triple negative breast cancer in vitro and in vivo.
May 01, 2010
Click here to read the entire abstract
Pubmed Data
: Cancer Res. 2010 May 1;70(9):3594-605. Epub 2010 Apr 13. PMID:
20388778
Article Published Date
: May 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
,
Flavonoids
,
Polyphenols
Diseases
:
Breast Cancer
,
Breast Cancer: Metastatic
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
Additional Keywords
:
Plant Extracts
[+]
Blueberry polyphenols extract is a potential prebiotic with anti-obesity effects.
Jan 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2019 Feb ;64:88-100. Epub 2018 Aug 11. PMID:
30471564
Article Published Date
: Jan 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
,
Polyphenols
,
Prebiotics
Diseases
:
Obesity
Pharmacological Actions
:
Gastrointestinal Agents
Additional Keywords
:
Anti-Obesity Agents
[+]
Boswellia is as effective as orlistat in preventing obesity, hyperlipidemia, steatosis, and insulin resistance through anti-inflammatory effects and upregulation of adiponectin.
Jun 01, 2019
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2019 Jun ;27(3):549-559. Epub 2018 Aug 1. PMID:
30069718
Article Published Date
: Jun 01, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Boswellia
,
Polyphenols
Diseases
:
Adiponectin: Low Levels
,
Hyperlipidemia
,
Insulin Resistance
,
Obesity
Pharmacological Actions
:
Adiponectin upregulation
,
Anti-Inflammatory Agents
,
Leptin Down-Regulation
Additional Keywords
:
Anti-Obesity Agents
,
Plant Extracts
[+]
Both curcumin and its metabolite tetrahydrocurcumin exert neuroprotection against chemically-induced neurotoxicity.
Apr 01, 2008
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2008 Apr;16(2):96-9. PMID:
18408903
Article Published Date
: Apr 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Flavonoids
,
Polyphenols
,
Tetrahydrocurcumin
Diseases
:
Neurodegenerative Diseases
,
Parkinson's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Buckwheat polyphenols protective effect against long-lasting impairment of spatial memory associated with hippocampal neuronal damage in rats subjected to repeated cerebral ischemia.
Apr 01, 2004
Click here to read the entire abstract
Pubmed Data
: J Pharmacol Sci. 2004 Apr;94(4):393-402. PMID:
15107579
Article Published Date
: Apr 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Buckwheat
,
Flavonoids
,
Polyphenols
Diseases
:
Brain Injury: Hippocampal Damage
,
Cerebral Ischemia
,
Memory Disorders
Pharmacological Actions
:
Neuroprotective Agents
[+]
Cacao polyphenol extract ameliorates experimental autoimmune myocarditis in mice.
Dec 09, 2015
Click here to read the entire abstract
Pubmed Data
: Hypertens Res. 2015 Dec 10. Epub 2015 Dec 10. PMID:
26657007
Article Published Date
: Dec 09, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Cocoa
,
Polyphenols
Diseases
:
Autoimmune Diseases
,
Myocarditis: Autoimmune
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
[+]
Cacao polyphenol extract suppresses dioxin-induced toxicity in mice.
Jan 01, 1993
Click here to read the entire abstract
Pubmed Data
: Clin Investig. 1993;71(8 Suppl):S134-6. PMID:
18928297
Article Published Date
: Jan 01, 1993
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Dioxin Toxicity
Additional Keywords
:
Plant Extracts
[+]
Cacao polyphenol extracts could protect animal kidneys against carbon tetrachloride.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Biosci Biotechnol Biochem. 2015 ;79(10):1669-75. Epub 2015 May 21. PMID:
25996516
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Cocoa
,
Polyphenols
Diseases
:
Kidney Damage: Chemically-Induced
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Renoprotective
[+]
Cardiac delayed repolarisation and atrioventricular conduction in rats with diabetes were halted by zingerone.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(12):e0189074. Epub 2017 Dec 5. PMID:
29206854
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
,
Polyphenols
Diseases
:
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Cardioprotective
[+]
Chia seed exerts a hypoglycemic and hypolipidemic effect in rats.
Sep 01, 2016
Click here to read the entire abstract
Pubmed Data
: Plant Foods Hum Nutr. 2016 Sep ;71(3):225-30. PMID:
27193017
Article Published Date
: Sep 01, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Fiber
,
Polyphenols
Diseases
:
Dyslipidemias
Pharmacological Actions
:
Hypoglycemic Agents
,
Hypolipidemic
[+]
Chokeberry fruit derivatives may act as a promising supplementary therapeutic option in the prevention and treatment of disorders occurring in metabolic syndrome, as well as their complications.
Nov 30, 2008
Click here to read the entire abstract
Pubmed Data
: Plant Foods Hum Nutr. 2008 Dec ;63(4):176-82. Epub 2008 Aug 23. PMID:
18726160
Article Published Date
: Nov 30, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Chokeberry
,
Flavonoids
,
Polyphenols
Diseases
:
Diabetes Mellitus: Type 2: Prevention
,
Hyperlipidemia
,
Lipid Peroxidation
,
Metabolic Syndrome X
Pharmacological Actions
:
Alpha-glucosidase inhibitor
,
Hypoglycemic Agents
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Cocoa extract has a protective efect on experimentally induced benign prostatic hyperplasia.
Dec 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2007 Dec;10(4):628-35. PMID:
18158833
Article Published Date
: Dec 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Prostatic Hyperplasia: Benign
Additional Keywords
:
Plant Extracts
[+]
Cocoa polyphenol has an antidepressant-like effect in rats.
Dec 01, 2008
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2008 Dec;11(6):269-76. PMID:
19000380
Article Published Date
: Dec 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
Additional Keywords
:
Plant Extracts
[+]
Cocoa polyphenols may inhibit tumor promotion through antioxidant and antiinflammatory mechanisms.
May 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2006 May;136(5):1150-5. PMID:
16614396
Article Published Date
: May 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Tumors
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
Coffee polyphenols modulate whole-body substrate oxidation and suppress postprandial hyperglycaemia, hyperinsulinaemia and hyperlipidaemia.
Jun 01, 2012
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2012 Jun ;107(12):1757-65. Epub 2011 Sep 29. PMID:
22017960
Article Published Date
: Jun 01, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Coffee
,
Polyphenols
Diseases
:
Hyperglycemia
,
Hyperinsulinism
,
Hyperlipidemia
Pharmacological Actions
:
Hypoglycemic Agents
,
Hypolipidemic
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Coffee polyphenols modulate whole-body substrate oxidation and suppress postprandial hyperglycaemia, hyperinsulinaemia and hyperlipidaemia.
Jun 01, 2012
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2012 Jun ;107(12):1757-65. Epub 2011 Sep 29. PMID:
22017960
Article Published Date
: Jun 01, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Coffee
,
Polyphenols
Diseases
:
Hyperglycemia
,
Hyperinsulinism
,
Hyperlipidemia
Pharmacological Actions
:
Hypoglycemic Agents
,
Hypolipidemic
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Combinations of natural anti-oxidants prevents metabolic syndrome by reducing oxidative stress.
Jun 25, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Redox Biol. 2015 Jun 26 ;6:206-217. Epub 2015 Jun 26. PMID:
26262997
Article Published Date
: Jun 25, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Grapefruit peel extract
,
Green Tea
,
Polyphenols
,
Vitamin C
,
Vitamin E
Diseases
:
Metabolic Diseases
,
Obesity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Glycation Agents
,
Antioxidants
,
Malondialdehyde Down-regulation
Additional Keywords
:
Risk Reduction
[+]
Compounds in oats are bioavailable and act synergistically with vitamin C enhance hamster and human LDL resistance to oxidation.
Jun 01, 2004
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2004 Jun;134(6):1459-66. PMID:
15173412
Article Published Date
: Jun 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Oats
,
Polyphenols
,
Vitamin C
Diseases
:
Cholesterol: Oxidation
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Natural Substance Synergy
[+]
Consumption of chokeberry polyphenols may play a role in prevention against female skeleton damage due to chronic exposure to cadmium.
Mar 04, 2015
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2015 Mar 5 ;229:132-46. Epub 2015 Feb 3. PMID:
25656917
Article Published Date
: Mar 04, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Chokeberry
,
Polyphenols
Diseases
:
Cadmium Poisoning
,
Heavy Metal Toxicity
[+]
Consumption of curcumin elevates fecal immunoglobulin A, an index of intestinal immune function, in rats fed a high-fat diet.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Nutr Sci Vitaminol (Tokyo). 2010;56(1):68-71. PMID:
20354349
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Flavonoids
,
Polyphenols
Diseases
:
IgA Deficiency
,
Immune Disorders: Low Immune Function
Pharmacological Actions
:
Immunomodulatory
Additional Keywords
:
Plant Extracts
[+]
Consumption of polyphenol-rich products may prevent Cadmium absorption from the diet polluted by this metal and its accumulation in the body, and thus also protect from its toxic action.
Jan 01, 2015
Click here to read the entire abstract
Pubmed Data
: Curr Drug Targets. 2015 Jan 2. Epub 2015 Jan 2. PMID:
25557255
Article Published Date
: Jan 01, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Chokeberry
,
Polyphenols
Diseases
:
Cadmium Poisoning
Pharmacological Actions
:
Hepatoprotective
,
Renoprotective
Additional Keywords
:
Detoxification
[+]
Consumption of some polyphenols reduces fecal deoxycholic acid and lithocholic acid, the secondary bile acids of risk factors of colon cancer.
Sep 23, 2009
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2009 Sep 23;57(18):8587-90. PMID:
19711910
Article Published Date
: Sep 23, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Caffeic Acid
,
Curcumin
,
Ellagic Acid
,
Flavonoids
,
Polyphenols
,
Rutin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
[+]
Consumption of two whole kiwifruit (Actinide chinensis) per day improves lipid homeostasis, fatty acid metabolism and gut microbiota in healthy rats.
Jul 31, 2020
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2020 Aug 1 ;156:186-195. Epub 2020 Apr 9. PMID:
32278604
Article Published Date
: Jul 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Kiwifruit
,
Polyphenols
Diseases
:
Lipid Peroxidation
Pharmacological Actions
:
Antioxidants
,
Gastrointestinal Agents
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Curcumin exhibits chemopreventive properties in hematogenous breast cancer metastases in immunodeficient mice.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: Cell Physiol Biochem. 2007;19(1-4):137-52. PMID:
17310108
Article Published Date
: Jan 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Flavonoids
,
Polyphenols
Diseases
:
Breast Cancer
,
Cancer Metastasis
,
Immune Disorders: Low Immune Function
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Apoptotic
,
NF-kappaB Inhibitor
[+]
Curcuminoids positively modulates oxidative damage and mitochondrial dysfunction in diabetic rat brain.
Nov 01, 2008
Click here to read the entire abstract
Pubmed Data
: Free Radic Res. 2008 Nov;42(11-12):999-1005. PMID:
19031318
Article Published Date
: Nov 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Flavonoids
,
Polyphenols
Diseases
:
Diabetes: Cognitive Dysfunction
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
Cyperus rotundus suppresses AGE formation and protein oxidation in a model of fructose-mediated protein glycoxidation.
Dec 01, 2007
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2007 Dec 1;41(5):572-8. Epub 2007 Jul 27. PMID:
17765965
Article Published Date
: Dec 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Cyperus rotundus
,
Flavonoids
,
Polyphenols
Diseases
:
Advanced Glycation End products (AGE)
,
Fructose-Induced Toxicity
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Dandelion polyphenols protect against acetaminophen-induced hepatotoxicity.
Jan 31, 2020
Click here to read the entire abstract
Pubmed Data
: Chin J Nat Med. 2020 Feb ;18(2):103-113. PMID:
32172946
Article Published Date
: Jan 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Dandelion
,
Polyphenols
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Hepatoprotective
,
Nrf2 activation
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Decreasing pro-inflammatory cytokine and reversing the immunosenescence with extracts of Pu-erh tea.
Dec 14, 2012
Click here to read the entire abstract
Pubmed Data
: Food Chem. 2012 Dec 15 ;135(4):2222-8. Epub 2012 Jul 15. PMID:
22980794
Article Published Date
: Dec 14, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Black Tea
,
Polyphenols
Diseases
:
Aging: Immunosenecence
,
Cancers: All
Pharmacological Actions
:
Immunomodulatory
,
Immunostimulatory
Additional Keywords
:
Plant Extracts
[+]
Dieckol reduces muscle atrophy.
Sep 29, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2021 Sep 30 ;10(10). Epub 2021 Sep 30. PMID:
34679696
Article Published Date
: Sep 29, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Polyphenols
Diseases
:
Hypertension
,
Muscle Atrophy
Pharmacological Actions
:
Immunomodulatory
[+]
Dietary constituents inhibit chemically-induced DNA and hemoglobin adductions associated with cancer.
Mar 01, 2003
Click here to read the entire abstract
Pubmed Data
: Appl Radiat Isot. 2003 Mar;58(3):291-8. PMID:
12595006
Article Published Date
: Mar 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Garlic
,
Grape Seed Extract
,
Polyphenols
,
Tea
,
Vitamin C
,
Vitamin E
Diseases
:
Chemical Exposure: Nitrobenzene
,
DNA damage
Pharmacological Actions
:
Antioxidants
,
Chemopreventive
[+]
dietary polyphenols play a significant role in the prevention of degenerative diseases via the improvement in colonic environment without any absorption from digestive tract.
Oct 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Biochem Nutr. 2015 Nov ;57(3):212-6. Epub 2015 Sep 29. PMID:
26566306
Article Published Date
: Oct 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Bilberry
,
Blue Honeysuckle
,
Chokeberry
,
Polyphenols
Diseases
:
High Fat Diet
Pharmacological Actions
:
Gastrointestinal Agents
Additional Keywords
:
Microbiota
,
Plant Extracts
[+]
Dietary supplementation with the polyphenol-rich açaí pulps improves cognition in aged rats and attenuates inflammatory signalling.
Nov 29, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2015 Nov 30. Epub 2015 Nov 30. PMID:
26618555
Article Published Date
: Nov 29, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Acai
,
Polyphenols
Diseases
:
Cognitive Decline/Dysfunction
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Dietary unripe apple polyphenol inhibits the development of food allergies in the mouse model.
Aug 15, 2005
Click here to read the entire abstract
Pubmed Data
: FEBS Lett. 2005 Aug 15;579(20):4485-91. PMID:
16081068
Article Published Date
: Aug 15, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Apples
,
Flavonoids
,
Polyphenols
,
Tannic Acid
Diseases
:
Food Allergies
Additional Keywords
:
Proanthocyanidins
[+]
Dose-dependent effects of cacao polyphenol intake on lipid metabolism.
May 31, 2021
Click here to read the entire abstract
Pubmed Data
: Plant Foods Hum Nutr. 2021 Jun ;76(2):254-255. Epub 2021 Apr 8. PMID:
33830369
Article Published Date
: May 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Cocoa
,
Polyphenols
Diseases
:
Obesity
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
Additional Keywords
:
Anti-Obesity Agents
[+]
Effect of acacia polyphenol supplementation on exercise-Induced oxidative stress in mice liver and skeletal muscle.
Dec 27, 2019
Click here to read the entire abstract
Pubmed Data
: Antioxidants (Basel). 2019 Dec 28 ;9(1). Epub 2019 Dec 28. PMID:
31905679
Article Published Date
: Dec 27, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Acacia catechu
,
Polyphenols
Diseases
:
Oxidative Stress
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Antioxidants
[+]
Effects of grape polyphenols on the Life span and neuroinflammatory alterations related to neurodegenerative disease-like disturbances.
Nov 15, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2020 Nov 16 ;25(22). Epub 2020 Nov 16. PMID:
33207644
Article Published Date
: Nov 15, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Grape Seed Extract
,
Polyphenols
Diseases
:
Neurodegenerative Diseases
,
Parkinson's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Effects of green tea polyphenols on iodide-induced autoimmune thyroiditis in nonobese diabetic mice.
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: Immunol Invest. 2013 ;42(3):235-46. Epub 2013 Mar 5. PMID:
23461615
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea
,
Polyphenols
,
Tea
Diseases
:
Hashimoto's thyroiditis
[+]
Embelia ribes has a cardioprotective effect against isoproterenol-induced myocardial infarcation in rats.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Indian J Exp Biol. 2008 Jan;46(1):35-40. PMID:
18697569
Article Published Date
: Jan 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Embelia ribes
,
Flavonoids
,
Polyphenols
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
Additional Keywords
:
Plant Extracts
[+]
Ethanol extracts of the peel Solanum tuberosum L. cv Jayoung led to the suppression of dermatitis in mice.
Jun 22, 2015
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2015 Jun 23. Epub 2015 Jun 23. PMID:
26102094
Article Published Date
: Jun 22, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Polyphenols
,
Potato
Diseases
:
Dermatitis
Pharmacological Actions
:
Dermatologic Agents
,
interleukin-13 down-regulation
,
Interleukin-4 downregulation
,
Interleukin-5 downregulation
Additional Keywords
:
Plant Extracts
[+]
Ethanolic extract of black chokeberry fruits not only has a potential value as a prophylactic agent but also may function as a nutritional supplement in the management of arterial hypertension.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2013 ;2013:912769. Epub 2013 Feb 27. PMID:
23533529
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Chokeberry
,
Polyphenols
Diseases
:
Hypertension: Arterial
,
Oxidative Stress
Pharmacological Actions
:
Antihypertensive Agents
,
Antioxidants
,
Prophylactic Agents
Additional Keywords
:
Prophylactic
[+]
EVOO polyphenols relieve synergistically autophagy dysregulation in a cellular model of Alzheimer's disease.
Jul 04, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2021 Jul 5 ;22(13). Epub 2021 Jul 5. PMID:
34281279
Article Published Date
: Jul 04, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Oleuropein
,
Olive Oil
,
Polyphenols
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Exosomes transport trace amounts of polyphenols.
Aug 17, 2020
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2020 Aug 18. Epub 2020 Aug 18. PMID:
32808000
Article Published Date
: Aug 17, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Polyphenols
Additional Keywords
:
Exosomes
[+]
Fenugreek (Trigonella foenum graecum) seed polyphenols protects the liver from alcohol toxicity.
Apr 01, 2007
Click here to read the entire abstract
Pubmed Data
: Pharmazie. 2007 Apr;62(4):299-304. PMID:
17484288
Article Published Date
: Apr 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Fenugreek
,
Flavonoids
,
Polyphenols
Diseases
:
Alcohol Toxicity
,
Alcoholic Liver Disease
Pharmacological Actions
:
Phase II Detoxification Enzyme Inducer
Additional Keywords
:
Plant Extracts
[+]
Fenugreek seed polyphenolic extract and quercetin compares favorably to metformin in improving insulin signaling, sensitivity and functioning in a rat model.
Apr 01, 2009
Click here to read the entire abstract
Pubmed Data
: Indian J Med Res. 2009 Apr;129(4):401-8. PMID:
19535835
Article Published Date
: Apr 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Fenugreek
,
Polyphenols
Diseases
:
Insulin Resistance
Additional Keywords
:
Drug: Metformin
,
Natural Substances Versus Drugs
,
Plant Extracts
[+]
Fenugreek seed polyphenols inhibit ethanol-induced damage in the rat liver.
Nov 01, 2007
Click here to read the entire abstract
Pubmed Data
: Cell Biol Toxicol. 2007 Nov;23(6):373-83. Epub 2007 Apr 24. PMID:
17453353
Article Published Date
: Nov 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Fenugreek
,
Polyphenols
Diseases
:
Alcoholic Liver Disease
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Fermented Pu-er tea can protect against damage from aflatoxin B1.
Mar 31, 2017
Click here to read the entire abstract
Pubmed Data
: J Sci Food Agric. 2017 Apr ;97(6):1910-1915. Epub 2016 Sep 22. PMID:
27539359
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Black Tea
,
Fermented Foods and Beverages
,
Green Tea
,
Polyphenols
Diseases
:
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Aflatoxin
[+]
Fish oil increases adiponectin and a combination of fish oil and apple polyphenols decrease cholesterol and oxidative stress.
Jan 01, 2017
Click here to read the entire abstract
Pubmed Data
: J Nutr Sci Vitaminol (Tokyo). 2017 ;63(1):21-27. PMID:
28367922
Article Published Date
: Jan 01, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Fish Oil
,
Polyphenols
Diseases
:
Adiponectin: Low Levels
,
High Cholesterol
,
Oxidative Stress
Pharmacological Actions
:
Adiponectin upregulation
,
Anticholesteremic Agents
,
Antioxidants
[+]
Fish oils and their combination with grape polyphenols could be beneficial against the negative effects of an unhealthy diet.
Dec 20, 2016
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2016 Dec 21 ;41:84-97. Epub 2016 Dec 21. PMID:
28064013
Article Published Date
: Dec 20, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Grape
,
Omega-3 Fatty Acids
,
Polyphenols
,
Polyunsaturated Fatty Acids (PUFAs)
Diseases
:
High Fat Diet
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Fructo-oligosaccharides and pectins enhance beneficial effects of raspberry polyphenols in rats with nonalcoholic fatty liver.
Mar 02, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2021 Mar 3 ;13(3). Epub 2021 Mar 3. PMID:
33802455
Article Published Date
: Mar 02, 2021
Study Type
: Animal Study
Additional Links
Substances
:
FOS (Fructooligosaccharides)
,
Pectin
,
Polyphenols
,
Raspberry
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Hypolipidemic
,
Interleukin-6 Downregulation
Additional Keywords
:
Natural Substance Synergy
[+]
Ginger and its derivatives may be effective herbal supplements for the clinical treatment of enterotoxigenic Escherichia coli diarrhea.
Oct 16, 2007
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2007 Oct 17 ;55(21):8390-7. Epub 2007 Sep 20. PMID:
17880155
Article Published Date
: Oct 16, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
,
Polyphenols
Diseases
:
Diarrhea
,
Escherichia coli Infections
Pharmacological Actions
:
Antidiarrheals
Additional Keywords
:
Phytotherapy
[+]
Ginger improved trinitrobenzene sulphonic acid-induced colitis via modulation of NF-κB activity and IL-1β signalling pathway.
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: Food Chem. 2013 Jan 1 ;136(1):170-7. Epub 2012 Aug 10. PMID:
23017409
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
,
Polyphenols
Diseases
:
Colitis
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Grape leaf extract has neuroprotective activities against aluminum chloride-induced cerebral damages and neurocognitive dysfunction.
Aug 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 Sep ;93:837-851. Epub 2017 Jul 14. PMID:
28715867
Article Published Date
: Aug 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Grape
,
Polyphenols
Diseases
:
Aluminum Toxicity
,
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Grape seed extract could improve imbalanced populations of intestinal microbiota, leading to prevention of obesity.
Mar 31, 2018
Click here to read the entire abstract
Pubmed Data
: J Food Sci. 2018 Apr ;83(4):1149-1152. Epub 2018 Mar 26. PMID:
29578242
Article Published Date
: Mar 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Grape Seed Extract
,
Polyphenols
Diseases
:
Obesity
Pharmacological Actions
:
Gastrointestinal Agents
Additional Keywords
:
Anti-Obesity Agents
[+]
Grape seed extract has bactericidal effects on MRSA.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Toxicol Sci. 2010;35(3):357-64. PMID:
20519844
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Grape Seed Extract
,
Polyphenols
Diseases
:
MRSA
Pharmacological Actions
:
Anti-Bacterial Agents
,
Antioxidants
[+]
Grape seed extract has inhibiting effect on the accumulation of age-related oxidative DNA damages in the central nervous system of rats.
Feb 15, 2006
Click here to read the entire abstract
Pubmed Data
: Brain Res Bull. 2006 Feb 15;68(6):469-73. Epub 2005 Nov 2. PMID:
16459205
Article Published Date
: Feb 15, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Aging: Brain
,
DNA damage
,
Neurodegenerative Diseases
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
,
Proanthocyanidins
[+]
Grape seed extract prevents adverse metabolic alterations through tis anti-inflammatory and antioxidant action.
Oct 01, 2017
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2017 Oct ;31(10):1621-1632. Epub 2017 Aug 25. PMID:
28840618
Article Published Date
: Oct 01, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Polyphenols
Diseases
:
Adiponectin: Low Levels
,
Inflammation
,
Insulin Resistance
,
Obesity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
Problem Substances
:
Insulin
[+]
Grape seed polyphenols and curcumin reduce genomic instability events in a transgenic mouse model for Alzheimer's disease.
Feb 10, 2009
Click here to read the entire abstract
Pubmed Data
: Mutat Res. 2009 Feb 10;661(1-2):25-34. Epub 2008 Nov 6. PMID:
19027755
Article Published Date
: Feb 10, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Flavonoids
,
Grapefruit Seed Extract
,
Polyphenols
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Genoprotective
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Grape-derived polyphenols produce antidepressant effects via VGF- and BDNF-dependent mechanisms.
May 09, 2019
Click here to read the entire abstract
Pubmed Data
: Ann N Y Acad Sci. 2019 May 10. Epub 2019 May 10. PMID:
31074515
Article Published Date
: May 09, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Grape Seed Extract
,
Polyphenols
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
,
Brain-derived neurotrophic factor modulator
[+]
Green tea has a growth inhibitory and antimetastatic effect on metastasis-specific mouse mammary cancer.
Mar 01, 2005
Click here to read the entire abstract
Pubmed Data
: Clin Cancer Res. 2005 Mar 1;11(5):1918-27. PMID:
15756018
Article Published Date
: Mar 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Green Tea
,
Polyphenols
Diseases
:
Breast Cancer: Lung Metastasis
,
Breast Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
[+]
Green tea has radioprotective properties against gamma-radiation exposure in mice.
Oct 01, 2008
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2008 Oct;22(10):1380-3. PMID:
18570224
Article Published Date
: Oct 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Green Tea
,
Polyphenols
,
Tea
Diseases
:
Radiation Induced Illness
Pharmacological Actions
:
Radioprotective
[+]
Green tea polyphenol and EGCG induce programmed cell death and inhibit invasion in human breast cancer cells.
Dec 01, 2007
Click here to read the entire abstract
Pubmed Data
: Cancer Biol Ther. 2007 Dec;6(12):1938-43. Epub 2007 Sep 1. PMID:
18059161
Article Published Date
: Dec 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Catechin
,
Flavonoids
,
Polyphenols
Diseases
:
Breast Cancer
,
Breast Cancer: Metastatic
Pharmacological Actions
:
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
[+]
Green tea polyphenol is able to attenuate alcoholic liver damage.
May 01, 2006
Click here to read the entire abstract
Pubmed Data
: Hepatobiliary Pancreat Dis Int. 2006 May;5(2):268-72. PMID:
16698589
Article Published Date
: May 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Green Tea
,
Polyphenols
Diseases
:
Alcoholic Liver Disease
Pharmacological Actions
:
Hepatoprotective
[+]
Green tea polyphenols (e.g. EGCG) have radioprotective properties.
May 01, 2010
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2010 May;35(10):1328-31. PMID:
20707208
Article Published Date
: May 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Catechin
,
Flavonoids
,
Green Tea
,
Polyphenols
Diseases
:
Radiation Induced Illness
Pharmacological Actions
:
Radioprotective
Additional Keywords
:
Plant Extracts
[+]
Green tea polyphenols and its constituent EGCG inhibits proliferation of human breast cancer cells in vitro and in vivo.
Jan 08, 2007
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 2007 Jan 8;245(1-2):232-41. Epub 2006 Mar 6. PMID:
16519995
Article Published Date
: Jan 08, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Catechin
,
Flavonoids
,
Green Tea
,
Polyphenols
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
[+]
Green tea polyphenols could decrease uric acid level through xanthine oxidase and renal urate transporters in hyperuricemic mice.
Sep 02, 2015
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2015 Sep 3. Epub 2015 Sep 3. PMID:
26344851
Article Published Date
: Sep 02, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea
,
Polyphenols
Diseases
:
Hyperuricemia
[+]
Green tea polyphenols decrease weight gain, ameliorate alteration of gut microbiota, and mitigate intestinal inflammation.
Dec 19, 2019
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2019 Dec 20 ;78:108324. Epub 2019 Dec 20. PMID:
32004926
Article Published Date
: Dec 19, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea
,
Polyphenols
Diseases
:
High Fat Diet
,
Inflammation
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Anti-Obesity Agents
[+]
Green tea polyphenols has a significant therapeutic effect on TNBS-induced colitis.
Feb 28, 2018
Click here to read the entire abstract
Pubmed Data
: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2018 Mar ;34(3):237-241. PMID:
29773105
Article Published Date
: Feb 28, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea
,
Polyphenols
Diseases
:
Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Green tea polyphenols improve isoflurane-induced cognitive impairment via modulating oxidative stress.
Oct 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2019 Nov ;73:108213. Epub 2019 Aug 1. PMID:
31704346
Article Published Date
: Oct 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea
,
Polyphenols
Diseases
:
Cognitive Decline/Dysfunction
,
Surgery: Anesthesiology
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
Green tea polyphenols mitigate deterioration of bone microarchitecture in middle-aged female rats.
Apr 01, 2009
Click here to read the entire abstract
Pubmed Data
: Bone. 2009 Apr;44(4):684-90. Epub 2008 Dec 11. PMID:
19118658
Article Published Date
: Apr 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Tea
Diseases
:
Osteoporosis
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Bone Quality
[+]
Green tea polyphenols modify the gut microbiome which correlated with a blood glucose lowering effect.
Jan 21, 2019
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2019 Jan 22:e1801064. Epub 2019 Jan 22. PMID:
30667580
Article Published Date
: Jan 21, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea
,
Polyphenols
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Hypoglycemic Agents
[+]
Green tea polyphenols prevent lipopolysaccharide-induced inflammatory liver injury.
Jun 11, 2019
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2019 Jun 12. Epub 2019 Jun 12. PMID:
31187838
Article Published Date
: Jun 11, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea
,
Polyphenols
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Green tea polyphenols protect against cyclosporine A nephrotoxicity.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2014 ;8(6):e65029. Epub 2013 Jun 3. PMID:
23755172
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea
,
Polyphenols
Diseases
:
Drug-Induced Toxicity: Cyclosporine
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
[+]
Green tea prevents and reverses fasting-induced intestinal mucosal damage.
Jun 01, 2003
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2003 Jun;19(6):536-40. PMID:
12781855
Article Published Date
: Jun 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Vitamin E
Diseases
:
Intestinal Diseases
Therapeutic Actions
:
Fasting/Caloric Restriction
Pharmacological Actions
:
Antioxidants
[+]
Green tea reduced ROS production, improving the redox status and reducing pro-inflammatory cytokine production by lymphocytes.
Aug 19, 2015
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2015 Aug 20. Epub 2015 Aug 20. PMID:
26299975
Article Published Date
: Aug 19, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea
,
Polyphenols
Diseases
:
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-2 Downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Green tea supplementation benefits body composition and improves bone properties in obese female rats fed with high-fat diet and caloric restricted diet.
Dec 01, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2015 Dec ;35(12):1095-105. Epub 2015 Oct 5. PMID:
26525915
Article Published Date
: Dec 01, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Polyphenols
Diseases
:
Adiponectin: Low Levels
,
Female
,
Obesity
,
Osteoporosis
Pharmacological Actions
:
Osteoprotective
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Green teaGreen tea polyphenol administration partly ameliorates irinotecan chemotherapy-induced side effects in the small intestine of mice.
Mar 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2007 Mar;137(3):634-40. PMID:
17311952
Article Published Date
: Mar 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
,
Green Tea
,
Polyphenols
Diseases
:
Chemotherapy-Induced Toxicity: Irinotecan
Pharmacological Actions
:
Antineoplastic Agents
[+]
Gut microbiota modulation by polyphenols from Aronia melanocarpa of LPS-induced liver diseases.
Mar 23, 2021
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2021 Mar 24 ;69(11):3312-3325. Epub 2021 Mar 10. PMID:
33688735
Article Published Date
: Mar 23, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Chokeberry
,
Polyphenols
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Hawthorn polyphenol extract could be used as a functional food component in the adjuvant treatment of T2D.
Mar 31, 2021
Click here to read the entire abstract
Pubmed Data
: Food Res Int. 2021 Apr ;142:110239. Epub 2021 Feb 25. PMID:
33773689
Article Published Date
: Mar 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Hawthorn
,
Polyphenols
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hypolipidemic
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
SIRT1 Activator
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Wnt/β-catenin signaling pathway modulation
[+]
Hawthorn polyphenol extract inhibits UVB-induced skin photoaging.
Aug 14, 2018
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2018 Aug 15 ;66(32):8537-8546. Epub 2018 Jul 31. PMID:
30032605
Article Published Date
: Aug 14, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Hawthorn
,
Polyphenols
Diseases
:
Aging Skin
,
Ultraviolet Radiation Induced Damage
Therapeutic Actions
:
Sunlight exposure
Pharmacological Actions
:
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Photoprotective
Additional Keywords
:
Plant Extracts
[+]
Hepatoprotective effects of zingerone on carbon tetrachloride- and dimethylnitrosamine-induced liver injuries in rats.
Jan 31, 2016
Click here to read the entire abstract
Pubmed Data
: Arch Pharm Res. 2016 Feb ;39(2):279-91. Epub 2015 Dec 14. PMID:
26667466
Article Published Date
: Jan 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
,
Polyphenols
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Hibiscus sabdariffa exerts effects similar to those of linagliptin, which improves insulin resistance and epithelial to mesenchymal transition.
Oct 07, 2014
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2014 Oct 8 ;62(40):9736-43. Epub 2014 Sep 26. PMID:
25226384
Article Published Date
: Oct 07, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Hibiscus sabdariffa
,
Polyphenols
Diseases
:
Diabetes Mellitus: Type 2
,
Diabetic Nephropathy
,
Insulin Resistance
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Natural Substances Versus Drugs
[+]
Hispolon protects rats from liver damage from carbon tetrachloride.
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2012 ;2012:480714. Epub 2011 Oct 15. PMID:
22013489
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Phellinus Linteus
,
Polyphenols
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Hispolon suppresses metastasis via autophagic degradation of cathepsin S in cervical cancer cells.
Jan 04, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Death Dis. 2017 10 5 ;8(10):e3089. Epub 2017 Oct 5. PMID:
28981104
Article Published Date
: Jan 04, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Phellinus Linteus
,
Polyphenols
Diseases
:
Cervical Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Cell cycle arrest
[+]
Incorporating polyphenol-enriched Oriental plum into a high-cholesterol diet can ameliorate some of the symptoms of neurodegenerative conditions.
Apr 12, 2015
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2015 Apr 13:1-8. Epub 2015 Apr 13. PMID:
25866056
Article Published Date
: Apr 12, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Plum
,
Polyphenols
Diseases
:
Alzheimer's Disease
,
High Cholesterol
,
Neurodegenerative Diseases
Pharmacological Actions
:
Hypolipidemic
,
Neuroprotective Agents
[+]
Increasing doses of blueberry polyphenols alters colonic metabolism and calcium absorption in ovariectomized rats.
May 31, 2020
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2020 Jun ;64(12):e2000031. Epub 2020 May 27. PMID:
32386352
Article Published Date
: May 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
,
Polyphenols
Pharmacological Actions
:
Gastrointestinal Agents
[+]
Ingestion of pomegranate polyphenols is associated with inhibition of x-ray-induced genomic instability and elevated GSH.
Sep 26, 2016
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2016 Sep 27:1-8. Epub 2016 Aug 27. PMID:
27673354
Article Published Date
: Sep 26, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Polyphenols
,
Pomegranate
Diseases
:
DNA damage
Pharmacological Actions
:
Genoprotective
,
Radioprotective
Anti Therapeutic Actions
:
X-ray Diagnostic Technologies
[+]
Inhibitory potential of Hydroxychavicol on Ehrlich ascites carcinoma model.
May 31, 2020
Click here to read the entire abstract
Pubmed Data
: Nat Prod Res. 2020 Jun ;34(11):1591-1596. Epub 2018 Nov 23. PMID:
30470141
Article Published Date
: May 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Betel
,
Polyphenols
Diseases
:
Ehrlich carcinoma
Pharmacological Actions
:
Antiproliferative
Additional Keywords
:
Plant Extracts
[+]
Kolaviron possibly possesses significant antihypertensive effect.
May 10, 2021
Click here to read the entire abstract
Pubmed Data
: J Complement Integr Med. 2021 May 11. Epub 2021 May 11. PMID:
33977689
Article Published Date
: May 10, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Garcinia kola
,
Polyphenols
Diseases
:
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
,
Antioxidants
,
Hypolipidemic
[+]
Licorice has hypocholesterolaemic and antioxidant effects.
Nov 01, 2006
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2006 Nov;50(11):1080-6. PMID:
17054099
Article Published Date
: Nov 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Licorice
,
Polyphenols
Diseases
:
Hypercholesterolemia
Pharmacological Actions
:
Anticholesteremic Agents
,
Antioxidants
[+]
Liver injury induced by carbon tetrachloride in mice is prevented by the antioxidant capacity of white tea polyphenols.
Mar 13, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2019 Mar 14 ;8(3). Epub 2019 Mar 14. PMID:
30875793
Article Published Date
: Mar 13, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Polyphenols
,
White Tea
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
,
Interleukin-1 beta downregulation
[+]
Long-term consumption of a myricitrin-supplemented diet may effectively protect against HFD-induced obesity and related metabolic disorders.
Oct 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Med Food. 2019 Nov ;22(11):1151-1158. Epub 2019 Sep 24. PMID:
31549892
Article Published Date
: Oct 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Polyphenols
Diseases
:
Dyslipidemias
,
Fatty Liver
,
High Fat Diet
,
Inflammation
,
Insulin Resistance
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Longan flower water extract has antiobesity and hypolipidemic effects.
Feb 10, 2010
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2010 Feb 10;58(3):2020-7. PMID:
20088600
Article Published Date
: Feb 10, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Flowers
,
Longan
,
Polyphenols
Diseases
:
Hyperlipidemia
,
Obesity
Additional Keywords
:
Plant Extracts
[+]
Lonicera caerulea L. berry polyphenols might inhibit LPS-induced inflammation by modulating both inflammatory and antioxidant mediators.
Jun 27, 2017
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2017 Jun 28 ;65(25):5133-5141. Epub 2017 Jun 14. PMID:
28573848
Article Published Date
: Jun 27, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Blue Honeysuckle
,
Polyphenols
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Nrf2 activation
[+]
Lychee seed polyphenol inhibits Aβ-induced activation of NLRP3 inflammasome.
Aug 04, 2020
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2020 Aug 5 ;130:110575. Epub 2020 Aug 5. PMID:
32768883
Article Published Date
: Aug 04, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Lychee
