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Pomegranate
Views 80587
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277 Diseases Researched for Pomegranate
Name
AC
CK
Focus
Oxidative Stress
31
126
Diabetes Mellitus: Type 2
11
84
Hypertension
10
59
Lipid Peroxidation
11
54
Inflammation
18
53
Hemodialysis
4
50
Prostate Cancer
12
48
Cardiovascular Diseases
4
41
Endothelial Dysfunction
4
36
Obesity
12
34
Polycystic Ovary Syndrome
3
30
Atherosclerosis
7
28
Breast Cancer
16
27
Rheumatoid Arthritis
6
26
Triglycerides: Elevated
4
24
Lipopolysaccharide-Induced Toxicity
4
22
Endotoxemia
2
20
Insulin Resistance
2
20
Intima Media Thickening
2
20
Nonalcoholic fatty liver disease (NAFLD)
7
20
Overweight
2
20
Prostate: PSA Doubling
2
20
Hyperglycemia
6
18
Diabetes: Oxidative Stress
4
16
Menopausal Syndrome
4
16
Chemically-Induced Liver Damage
7
15
Dysbiosis
4
15
Wound Healing
9
15
Alzheimer's Disease
9
14
Cognitive Decline/Dysfunction
3
14
Colorectal Cancer
3
14
Memory Disorders
3
14
Ulcerative Colitis
3
14
Aging Skin
3
13
Diabetic Complications
7
13
Neurodegenerative Diseases
7
13
Osteoarthritis
6
13
Arteriosclerosis
2
12
Chemotherapy and Radiation Toxicity
2
12
High Fat Diet
5
12
Liver Fibrosis
5
12
Lung Injury: Smoke-Induced
3
12
Metabolic Syndrome X
2
12
Myocardial Ischemia
2
12
Osteoarthritis: Knee
2
12
Periodontal Diseases
2
12
Streptococcus Infections
3
12
Ultraviolet Radiation Induced Damage
2
12
Athletic Performance
2
11
Athletic Performance: Recovery
2
11
Hyperlipidemia
6
11
Metabolic Diseases
2
11
Periodontitis
2
11
Staphylococcus aureus infection
11
11
Aging: Brain
1
10
Angina Pectoris
1
10
Arterial Thickening
1
10
C-Reactive Protein
1
10
Carotid Artery Narrowing
1
10
Carotid Stenosis
1
10
Chemotherapy-Induced Toxicity: Gentamicin
5
10
Cholesterol: Oxidation
1
10
Chronic Kidney Disease (CKD)
1
10
Dyslipidemias
1
10
Head and Neck Cancer
1
10
High Cholesterol
1
10
Kidney Failure
1
10
Memory Loss
1
10
Muscle Damage
1
10
Muscle Damage: Exercise-Induced
1
10
Muscle Soreness: Exercise-Induced
1
10
Nicotine/Tobacco Toxicity
1
10
Prenatal Chemical Exposures
1
10
Radiation Induced Illness: Mucositis
1
10
Smoking Cessation: Nicotine Addiction
1
10
Stroke: Attenuation/Recovery
1
10
Wrinkles
1
10
Cancers: All
9
9
Candidiasis
3
9
Liver Cancer
6
9
Osteoporosis
5
9
Chemotherapy-Induced Toxicity: Cisplatin
5
8
Kidney Damage
4
8
Escherichia coli Infections
7
7
Aluminum Toxicity
2
6
Colitis
3
6
Colon Cancer
5
6
Drug Toxicity: Methotrexate
2
6
Hepatic Steatosis
3
6
Lung Cancer
5
6
Multiple Myeloma
2
6
Benzo[a]pyrene-induced Toxicity
3
5
Coronary Artery Disease
3
5
Salmonella Infections
4
5
Staphylococcus epidermidis
4
5
Tobacco Toxicity
1
5
Acetaminophen (Tylenol) Toxicity
2
4
Aging
2
4
Barium Toxicity
2
4
Bladder Cancer
2
4
Brain Hypoxia
2
4
Brain Ischemia
2
4
Brain: Oxidative Stress
2
4
Burns
2
4
Chemotherapy-Induced Toxicity: Cyclophosphamide
2
4
Chemotherapy-Induced Toxicity: 5-fluorouracil
3
4
Citrobacter Infection
2
4
DNA damage
2
4
Depression: Postmenopausal
2
4
Fungal Infection
3
4
Hypoglycemia
3
4
Infertility: Male
2
4
Inflammatory Bowel Diseases
3
4
Ischemia
2
4
Kidney Damage: Chemically-Induced
2
4
Klebsiella Infections
3
4
Liver Damage
2
4
Malaria
2
4
Pseudomonas aeruginosa
4
4
Acne
2
3
Advanced Glycation End products (AGE)
2
3
Breast Cancer: Triple Negative
3
3
Cancer Metastasis
2
3
Candida Albicans
2
3
Cervical Cancer
2
3
Diabetes
2
3
Diabetes: Cognitive Dysfunction
2
3
Estrogen Deficiency
2
3
Kidney Stones
2
3
Leishmaniasis
2
3
Listeria Infections
3
3
Ovarian Cancer
2
3
Parasitic Diseases
2
3
Skin Diseases: Photo-Aging
3
3
Steptococcus Mutans Infections
3
3
Air Pollution Linked Toxicity
2
2
Alcohol Toxicity
1
2
Antibiotic Toxicity
1
2
Anxiety
1
2
Anxiety Disorders
1
2
Arthritis
1
2
Aspirin-Induced Toxicity
1
2
Bacillus Cereus infection
2
2
Biliary Obstruction
1
2
Blood Sugar Problems
1
2
Brain Inflammation
2
2
Brain: Microglial Activation
1
2
Breast Cancer Stem Cells
2
2
Cachexia
1
2
Cancer: Prostate
1
2
Candida Infection
2
2
Carcinoma: Non-Small-Cell Lung
2
2
Cardiotoxicity: Chemotherapy-Induced
1
2
Cerebral Ischemia
1
2
Chemical Exposure
1
2
Chemotherapy-Induced Liver Toxicity
1
2
Chemotherapy-Induced Toxicity
1
2
Chronic Obstructive Pulmonary Disease
1
2
Clogged Arteries
1
2
Colitis: Ulcerative
1
2
Coronavirus Infection
2
2
Creutzfeldt-Jakob disease
1
2
Cystitis: Hemorrhagic
1
2
Dementia
1
2
Depression
1
2
Dermatitis: Contact
1
2
Diabetes: Cardiovascular Illness
1
2
Diabetic Retinopathy
1
2
Diarrhea
1
2
Drug-Induced Toxicity: Methotrexate
1
2
Encephalomyelitis
1
2
Erectile Dysfunction
1
2
Fetal Origin of Adult Disease
1
2
Fibrosis: Liver
1
2
Fluoride Toxicity
1
2
Gastric Ulcer
1
2
Gastrointestinal Inflammation
1
2
Gestational Diabetes
1
2
HIV Infections
2
2
Hearing Loss
1
2
Hepatitis: Autoimmune
1
2
High Fructose Diet
1
2
Hypercholesterolemia
1
2
Hyperpigmentation
2
2
Hypoxia
1
2
Immune Disorders: Low Immune Function
1
2
Infertility
1
2
Influenza
2
2
Influenza A
2
2
Jaundice
1
2
Jaundice: Post-Hepatic/Obstructive
1
2
Kidney Failure: Acute
1
2
Lead Poisoning
1
2
Leukemia
2
2
Lung Cancer: Metastatic
1
2
Lung Cancer: Prevention
1
2
Lung Injury: Acute
1
2
Melanoma
1
2
Memory Disorders: Drug-Induced
1
2
Mycobacterium tuberculosis
2
2
NSAID-induced toxicity
1
2
Oral Cancer
2
2
Pancreatic Cancer
2
2
Pancreatitis
1
2
Parkinson's Disease
1
2
Pesticide Toxicity
1
2
Porphyromonas gingivalis
1
2
Pregnancy Complications
1
2
Prion Diseases
1
2
Prostate Cancer: Prevention
1
2
Radiation Induced Illness
1
2
Respiratory Infections
1
2
Sepsis
1
2
Skin Cancer: Prevention
1
2
Smoking
1
2
Staphylococcus aureus: Methicillin-resistant (MRSA)
2
2
Stress
1
2
Subarachnoid hemorrhage
1
2
Tapeworm Infection
1
2
Tuberculosis
1
2
Tuberculosis: Drug Resistant
1
2
Uterus: Contraction/Expulsion Disorders
1
2
Vaginal Atrophy
1
2
Wound Healing: Delayed
1
2
Adenoviridae Infections
1
1
Aflatoxicosis
1
1
Avian Influenza
1
1
Bacillus subtilis infections
1
1
Breast Cancer: Chemically-Induced
1
1
Breast Cancer: Estrogen
1
1
Breast Cancer: Metastatic
1
1
Breast Cancer: Prevention
1
1
Campylobacter Infections
1
1
Cancer Stem Cells
1
1
Candida Glabrata
1
1
Chemotherapy-Induced Kidney Damage
1
1
Cholera
1
1
Chronic Disease
1
1
Chronic Myeloid Leukemia
1
1
Clostridium Infections
1
1
Common Cold
1
1
Coronavirus Disease
1
1
Dental Caries
1
1
Diabetes Mellitus: Type 2: Prevention
1
1
Enterobacteriaceae Infections
1
1
Enveloped Viruses
1
1
Estrogen Dominance
1
1
Foodborne Pathogens: Prevention/Food Preservation
1
1
Gram-Negative Bacterial Infections
1
1
Gram-Positive Bacterial Infections
1
1
H3N2 Infection
1
1
Helicobacter Pylori Infection
1
1
Hepatitis B
1
1
Hepatitis C
1
1
Herpes Simplex Virus Type 1
1
1
Herpes Simplex Virus Type 2
1
1
Herpes family viruses
1
1
Hydrogen Peroxide Induced Toxicity
1
1
Infection: Antibiotic Resistant
1
1
MRSA
1
1
Mucositis
1
1
Mycotoxin Toxicity
1
1
Oral Candidosis
1
1
Oral Infection
1
1
Poxviruses
1
1
Pseudomonas Infections
1
1
SARS
1
1
Shigellosis
1
1
Skin Cancer
1
1
Squamous cell carcinoma
1
1
Staphylococcal Infections
1
1
Streptococcus pyogenes
1
1
Typhoid Fever
1
1
Vaccinia virus
1
1
Vibrio Infections
1
1
Viral Infections
1
1
Zika Virus
1
1
114 Pharmacological Actions Researched for Pomegranate
Name
AC
CK
Focus
Antioxidants
121
378
Anti-Inflammatory Agents
74
246
Antihypertensive Agents
10
94
Tumor Necrosis Factor (TNF) Alpha Inhibitor
18
70
Hypoglycemic Agents
15
66
Interleukin-6 Downregulation
14
65
Neuroprotective Agents
22
59
Cardioprotective
7
55
Malondialdehyde Down-regulation
11
53
Gastrointestinal Agents
8
49
Hypolipidemic
12
48
Hepatoprotective
22
44
Chemopreventive
21
43
Anti-Bacterial Agents
25
37
Anti-atherogenic
6
35
Renoprotective
16
30
Antiproliferative
25
29
NF-kappaB Inhibitor
11
29
Antimicrobial
16
28
Chemoprotective Agents
15
25
Apoptotic
15
22
Anti-Apoptotic
9
19
Insulin Sensitizers
3
18
Matrix metalloproteinase-2 (MMP-2) inhibitor
6
16
Matrix metalloproteinase-9 (MMP-9) inhibitor
6
16
Anti-metastatic
13
15
Anticarcinogenic Agents
7
14
Radioprotective
3
14
Cyclooxygenase 2 Inhibitors
8
12
Interleukin-1 beta downregulation
7
12
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
2
12
Photoprotective
2
12
Antifungal Agents
6
11
Antiviral Agents
11
11
Anti Inflammatory
1
10
Anti-collagenase
1
10
Anticholesteremic Agents
4
10
Cardiotonic Agents
1
10
Cardiovascular Agents
1
10
Cell cycle arrest
6
10
Cytoprotective
4
10
Ergogenic
1
10
Gastroprotective
6
10
Vasodilator Agents
1
10
anti-inflammatory
1
10
Chondroprotective
2
7
Prophylactic Agents
4
7
Anti-Fibrotic
4
6
Antidepressive Agents
3
6
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
3
6
Immunomodulatory
5
6
MicroRNA modulator
3
6
Tumor Suppressor Protein p53 Upregulation
4
6
Angiotensin-Converting Enzyme Inhibitors
3
5
Chemotherapeutic
5
5
Cyclin D1 Down-Regulation
3
5
Cytotoxic
1
5
Vasoprotective
2
5
Alpha-glucosidase inhibitor
4
4
Anti-Anxiety Agents
2
4
Anti-Ulcer Agents
2
4
Antimutagenic Agents
3
4
Antinoceceptive
2
4
Bax/Bcl2 ratio: Increase
3
4
Chemosensitizer
3
4
Interferon Gamma Reducer
2
4
Nrf2 activation
2
4
Osteoprotective
2
4
Angiogenesis Inhibitors
2
3
Anti-Infective Agents
2
3
Antineoplastic Agents
3
3
Antiparasitic Agents
2
3
Leishmanicidal
2
3
Prostaglandin PGE2 downregulation
2
3
Analgesics
1
2
Anti-Angiogenic
2
2
Antidiarrheals
1
2
Antimalarials
1
2
Antitubercular Agents
1
2
Aromatase Inhibitors
2
2
Bcl-2 protein down-regulation
1
2
Brain-derived neurotrophic factor modulator
1
2
Caspase-3 Activation
1
2
Cholinesterase Inhibitors
1
2
Fertility Agents
1
2
Fertility Agents: Male
1
2
Genoprotective
1
2
Glutathione S-transferase Inhibitor
1
2
Heat Shock Protein Down-Regulation
1
2
Immunostimulatory
1
2
Interleukin-10 downregulation
1
2
Interleukin-17 downregulation
1
2
Interleukin-18 down-regulation
1
2
Nitric Oxide Enhancer
1
2
Osteogenic
1
2
Pancreato Protective Agents
1
2
Regenerative
1
2
SGLT1 inducer
1
2
Selective estrogen enzyme modulator (SEEM)
2
2
Superoxide Dismutase Up-regulation
1
2
Uterotonic
1
2
Vascular Endothelial Growth Factor Inhibitors
2
2
Wnt/β-catenin signaling pathway modulation
2
2
apoptosis
1
2
Alpha-amylase inhibitor
1
1
Anti-Proliferative
1
1
Enzyme Inhibitors
1
1
Estrogen Receptor Modulators
1
1
Heme oxygenase-1 up-regulation
1
1
Nitric Oxide Inhibitor
1
1
P21 Activation
1
1
Selective Estrogen Receptor Modulators
1
1
Tyrosinase inhibitors
1
1
Viral Hemagglutinin Inhibitor
1
1
Research Articles
405
Cumulative Knowledge Score
655
Overall Research Rating
EXCELLENT
Related Topics
The Following are Sub-Topics of Pomegranate
Pomegranate Peel
Pomegranate Seed
Pomegranate flower
Pomegranate Polyphenols
Pomegranate is a Sub of the following Topic
Fruit: All
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View the Evidence:
519 Abstracts with Pomegranate Research
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[+]
The effects of pomegranate supplementation on biomarkers of inflammation and endothelial dysfunction.
Feb 29, 2020
Click here to read the entire abstract
Pubmed Data
: Complement Ther Med. 2020 Mar ;49:102358. Epub 2020 Feb 26. PMID:
32147056
Article Published Date
: Feb 29, 2020
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Pomegranate
Diseases
:
Endothelial Dysfunction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
The present meta-analysis suggests consistent benefits of pomegranate juice consumption on blood pressure.
Nov 22, 2016
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2016 Nov 23 ;115:149-161. Epub 2016 Nov 23. PMID:
27888156
Article Published Date
: Nov 22, 2016
Study Type
: Meta Analysis
Additional Links
Substances
:
Pomegranate
Diseases
:
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
[+]
This review provides support for the use of polyphenol-rich interventions for improving cardiovascular risk markers in haemodialysis patients.
Dec 10, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Dec 11 ;9(12). Epub 2017 Dec 11. PMID:
29232891
Article Published Date
: Dec 10, 2017
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Cocoa
,
Polyphenols
,
Pomegranate
,
Turmeric
Diseases
:
Cardiovascular Diseases
,
Hemodialysis
Pharmacological Actions
:
Antihypertensive Agents
,
Cardioprotective
Additional Keywords
:
Risk Reduction
[+]
4 weeks treatment with the pomegranate supplement significantly ameliorates the irritating symptoms of menopause.
Jan 31, 2022
Click here to read the entire abstract
Pubmed Data
: Complement Ther Clin Pract. 2022 Feb ;46:101544. Epub 2022 Feb 2. PMID:
35134697
Article Published Date
: Jan 31, 2022
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Menopausal Syndrome
[+]
A polyphenol-rich whole food supplement significantly effected the rate of PSA progression among men with prostate cancer.
Mar 10, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Prostate Cancer Prostatic Dis. 2014 Mar 11. Epub 2014 Mar 11. PMID:
24614693
Article Published Date
: Mar 10, 2014
Study Type
: Human Study
Additional Links
Substances
:
Broccoli
,
Green Tea
,
Polyphenols
,
Pomegranate
,
Turmeric
Diseases
:
Prostate: PSA Doubling
,
Prostate Cancer
Additional Keywords
:
Supplements
[+]
A proprietary blend of standardized Punica granatum fruit rind and Theobroma cocoa seed extracts mitigates aging males' symptoms.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Med Sci. 2022 ;19(8):1290-1299. Epub 2022 Jul 11. PMID:
35928723
Article Published Date
: Dec 31, 2021
Study Type
: Human Study
Additional Links
Substances
:
Cocoa
,
Pomegranate
Diseases
:
Aging
,
Low Testosterone
Additional Keywords
:
Plant Extracts
[+]
Antenatal intake of pomegranate may limit placental injury and thereby may confer protection to the exposed fetus.
Feb 28, 2012
Click here to read the entire abstract
Pubmed Data
: Am J Physiol Endocrinol Metab. 2012 Feb 28. Epub 2012 Feb 28. PMID:
22374759
Article Published Date
: Feb 28, 2012
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Prenatal Chemical Exposures
[+]
Comparison of antifungal efficacy of ethanolic extracts of Woodfordia fruticosa leaf and Punica granatum peel in uncontrolled diabetic patients wearing removable dentures.
Aug 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Curr Med Mycol. 2020 Sep ;6(3):15-20. PMID:
33834138
Article Published Date
: Aug 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
,
Woodfordia fruticosa
Diseases
:
Candida Infection
Pharmacological Actions
:
Antifungal Agents
[+]
Concentrated pomegranate juice appeared to have favourable effects on certain markers of subclinical inflammation in diabetic patients.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Endocrinol Metab. 2016 Jan ;14(1):e33835. Epub 2016 Jan 30. PMID:
27279834
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Diabetes Mellitus: Type 2
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
Additional Keywords
:
Risk Reduction
[+]
Consuming daily synbiotic pomegranate juice improved metabolic, oxidative, inflammatory, and blood pressure outcomes in females with PCOS.
Nov 10, 2019
Click here to read the entire abstract
Pubmed Data
: J Endocrinol Invest. 2019 Nov 11. Epub 2019 Nov 11. PMID:
31713129
Article Published Date
: Nov 10, 2019
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Polycystic Ovary Syndrome
Pharmacological Actions
:
Antihypertensive Agents
,
Antioxidants
,
Cardioprotective
[+]
Consumption of fruits that are high in antioxidants could represent a useful means to improve the antioxidant status of NAFLD.
Jul 13, 2016
Click here to read the entire abstract
Pubmed Data
: Int J Vitam Nutr Res. 2016 Jul 14:1-7. Epub 2016 Jul 14. PMID:
27414418
Article Published Date
: Jul 13, 2016
Study Type
: Human Study
Additional Links
Substances
:
Orange
,
Pomegranate
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
[+]
Consumption of pomegranate decreases plasma lipopolysaccharide-binding protein levels, a marker of metabolic endotoxemia.
May 16, 2018
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2018 May 17. Epub 2018 May 17. PMID:
29770393
Article Published Date
: May 16, 2018
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Colorectal Cancer
,
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Gastrointestinal Agents
[+]
Consumption of pomegranate decreases serum oxidative stress and reduces disease activity in patients with active rheumatoid arthritis.
Aug 01, 2011
Click here to read the entire abstract
Pubmed Data
: Isr Med Assoc J. 2011 Aug ;13(8):474-9. PMID:
21910371
Article Published Date
: Aug 01, 2011
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Lipid Peroxidation
,
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Consumption of pomegranate extract decreased endotoxemia in overweight-obese individuals by reshaping the gut microbiota.
May 31, 2018
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2018 Jun ;62(11):e1800160. Epub 2018 May 17. PMID:
29665619
Article Published Date
: May 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
C-Reactive Protein
,
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Gastrointestinal Agents
Additional Keywords
:
Microbiota
[+]
Consumption of pomegranate juice improved MDA levels and carbonyls, and thus decreased the oxidative damage caused by exercise.
Dec 06, 2015
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2015 Dec 7. Epub 2015 Dec 7. PMID:
26778544
Article Published Date
: Dec 06, 2015
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Oxidative Stress
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
[+]
Consumption of pomegranate peel extract in combination with vitamin E enhanced the inflammatory status and endothelial function in hemodialysis patients.
Aug 24, 2020
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2020 Aug 25. Epub 2020 Aug 25. PMID:
32839797
Article Published Date
: Aug 24, 2020
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate Peel
,
Vitamin E
Diseases
:
Endothelial Dysfunction
,
Hemodialysis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Consumption of watermelon juice enriched in I-citrulline and pomegranate ellagitannins enhanced metabolism during physical exercise.
Jun 06, 2017
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2017 Jun 7 ;65(22):4395-4404. Epub 2017 May 26. PMID:
28513179
Article Published Date
: Jun 06, 2017
Study Type
: Human Study
Additional Links
Substances
:
Citrulline
,
Pomegranate
,
Watermelon
Diseases
:
Muscle Damage
Therapeutic Actions
:
Exercise
[+]
Daily consumption of pomegranate juice may stabilize the ability to learn visual information over a 12-month period.
Nov 11, 2019
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2019 Nov 12. Epub 2019 Nov 12. PMID:
31711104
Article Published Date
: Nov 11, 2019
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Aging: Brain
,
Memory Disorders
Pharmacological Actions
:
Neuroprotective Agents
[+]
Daily oral pomegranate consumption may lead to enhanced protection from ultraviolet photodamage.
Oct 09, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2019 Oct 10 ;9(1):14528. Epub 2019 Oct 10. PMID:
31601842
Article Published Date
: Oct 09, 2019
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Photoprotective
[+]
Effects of natural polyphenol-rich pomegranate juice on the acute and delayed response of Homocysteine and steroidal hormones following weightlifting exercises.
Mar 05, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Int Soc Sports Nutr. 2020 Mar 6 ;17(1):15. Epub 2020 Mar 6. PMID:
32143716
Article Published Date
: Mar 05, 2020
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
,
Pomegranate
Diseases
:
Athletic Performance
[+]
Efficacy of pomegranate seed powder on glucose and lipid metabolism in patients with type 2 diabetes.
Dec 09, 2020
Click here to read the entire abstract
Pubmed Data
: Complement Med Res. 2020 Dec 10:1-8. Epub 2020 Dec 10. PMID:
33302270
Article Published Date
: Dec 09, 2020
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Hypoglycemic Agents
[+]
Extracts of gotu kola and pomegranate improve clinical symptoms of chronic periodontitis.
Jul 01, 2005
Click here to read the entire abstract
Pubmed Data
: J Int Acad Periodontol. 2005 Jul;7(3):70-9. PMID:
16022023
Article Published Date
: Jul 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Gotu Kola
,
Pomegranate
Diseases
:
Periodontitis
[+]
Fresh pomegranate juice decreases fasting serum erythropoietin in patients with type 2 diabetes.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Food Sci. 2019 ;2019:1269341. Epub 2019 Apr 18. PMID:
31139640
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Diabetes Mellitus: Type 2
[+]
GranaGard administration to MS patients might improve/stabilize cognitive disability.
Aug 31, 2021
Click here to read the entire abstract
Pubmed Data
: Mult Scler Relat Disord. 2021 Sep ;54:103103. Epub 2021 Jun 27. PMID:
34243101
Article Published Date
: Aug 31, 2021
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Cognitive Decline/Dysfunction
,
Multiple Sclerosis
Pharmacological Actions
:
Neuroprotective Agents
[+]
Human volunteers treated with pomegranate seed oil showed substantial amelioration of skin inflammation.
Jan 15, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2023 Jan 16 ;28(2). Epub 2023 Jan 16. PMID:
36677961
Article Published Date
: Jan 15, 2023
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate Seed
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
in the form of a new beverage can improve insulin resistance, insulin, testosterone level, BMI, weight and waist circumference in PCOS.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Nutr Metab Cardiovasc Dis. 2019 02 ;29(2):201-208. Epub 2018 Jul 17. PMID:
30538082
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
,
Probiotics
Diseases
:
Insulin Resistance
,
Polycystic Ovary Syndrome
Pharmacological Actions
:
Hypoglycemic Agents
,
Insulin Sensitizers
[+]
In UA producers, the genera Butyrivibrio, Enterobacter, Escherichia, Lactobacillus, Prevotella, Serratia and Veillonella were increased and Collinsella decreased significantly at week 4 compared to baseline.
Jul 19, 2015
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2015 Jul 20. Epub 2015 Jul 20. PMID:
26189645
Article Published Date
: Jul 19, 2015
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
,
Urolithin A
Diseases
:
Dysbiosis
Pharmacological Actions
:
Gastrointestinal Agents
Additional Keywords
:
Metabolites
,
Microbiota
[+]
Optimized curcumin, pomegranate extract, and methylsulfonylmethane reduce acute, systemic inflammatory response to a half-marathon race.
Jun 30, 2020
Click here to read the entire abstract
Pubmed Data
: Altern Ther Health Med. 2020 Jul 1. Epub 2020 Jul 1. PMID:
32619204
Article Published Date
: Jun 30, 2020
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
,
MSM (Methylsulfonylmethane)
,
Pomegranate
Diseases
:
Inflammation
,
Muscle Damage: Exercise-Induced
Therapeutic Actions
:
Exercise: Running
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Pharmacological therapy determines the gut microbiota modulation by a pomegranate extract nutraceutical in metabolic syndrome.
Dec 21, 2021
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2021 Dec 22:e2001048. Epub 2021 Dec 22. PMID:
33458928
Article Published Date
: Dec 21, 2021
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Metabolic Syndrome X
Pharmacological Actions
:
Gastrointestinal Agents
[+]
Polyphenol and methylsulfonylmethane supplementation improves immune, DAMP signaling, and inflammatory responses during recovery from all-out running efforts.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Physiol. 2021 ;12:712731. Epub 2021 Aug 31. PMID:
34531760
Article Published Date
: Dec 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
,
MSM (Methylsulfonylmethane)
,
Polyphenols
,
Pomegranate Polyphenols
Diseases
:
Inflammation
Therapeutic Actions
:
Exercise: Running
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Polyphenols on the outcomes of inflammatory factors and oxidative stress in patients with type 2 diabetes mellitus.
Feb 10, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Rev Cardiovasc Med. 2022 Feb 11 ;23(2):57. PMID:
35229548
Article Published Date
: Feb 10, 2022
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
,
Pomegranate Peel
Diseases
:
Diabetes: Oxidative Stress
,
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Pomegranate and chamomile plant extracts had antimicrobial and anti-inflammatory properties similar to that of chlorhexidine 0.12%.
Jan 31, 2014
Click here to read the entire abstract
Pubmed Data
: Complement Ther Clin Pract. 2014 Feb ;20(1):93-8. Epub 2013 Sep 25. PMID:
24439653
Article Published Date
: Jan 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Chamomile
,
Pomegranate
Diseases
:
Periodontal Diseases
Pharmacological Actions
:
anti-inflammatory
,
Antimicrobial
Additional Keywords
:
Natural Substances Versus Drugs
,
Plant Extracts
[+]
Pomegranate and licorice drinks could increase the metabolism rate for nicotine.
Sep 27, 2016
Click here to read the entire abstract
Pubmed Data
: J Pharm Biomed Anal. 2016 Sep 28 ;132:60-65. Epub 2016 Aug 28. PMID:
27693954
Article Published Date
: Sep 27, 2016
Study Type
: Human Study
Additional Links
Substances
:
Licorice
,
Pomegranate
Diseases
:
Nicotine/Tobacco Toxicity
,
Smoking Cessation: Nicotine Addiction
[+]
Pomegranate consumption can improve physical function and stiffness, decrease breakdown cartilage enzymes and increase antioxidant status.
Jan 24, 2016
Click here to read the entire abstract
Pubmed Data
: J Sci Food Agric. 2016 Jan 25. Epub 2016 Jan 25. PMID:
26804926
Article Published Date
: Jan 24, 2016
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Osteoarthritis: Knee
Pharmacological Actions
:
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
[+]
Pomegranate extract can ameliorate some clinical symptoms and reduce neutrophils, basophils, and eosinophils in allergic asthma patients.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2023 ;14:1109966. Epub 2023 Jan 25. PMID:
36762119
Article Published Date
: Dec 31, 2022
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Asthma
Pharmacological Actions
:
Anti-Asthmatic Agents
[+]
Pomegranate extract can improve lung function parameters and IL-35 expression in mild and moderate allergic asthma.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Nutr. 2022 ;9:1026343. Epub 2022 Oct 18. PMID:
36330147
Article Published Date
: Dec 31, 2021
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Asthma
Pharmacological Actions
:
Anti-Asthmatic Agents
[+]
Pomegranate extract consumption may reduce complications linked with obesity.
Jan 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Complement Ther Clin Pract. 2016 Feb ;22:44-50. Epub 2015 Dec 12. PMID:
26850805
Article Published Date
: Jan 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hypoglycemic Agents
,
Hypolipidemic
Additional Keywords
:
Plant Extracts
[+]
Pomegranate extract may be effective in improving performance outcomes at maximal effort and might help to restore force in the damaged muscles.
Mar 27, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Mar 28 ;11(4). Epub 2019 Mar 28. PMID:
30925733
Article Published Date
: Mar 27, 2019
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Athletic Performance: Recovery
Therapeutic Actions
:
Exercise: Cycling
[+]
Pomegranate extract supplementation enhanced vessel diameter and blood flow, suggesting possible exercise performance enhancement.
Mar 31, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Sport Sci. 2017 Apr ;17(3):317-325. Epub 2016 Sep 20. PMID:
27644475
Article Published Date
: Mar 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Athletic Performance
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Vasodilator Agents
Additional Keywords
:
Plant Extracts
[+]
Pomegranate extract supplementation may reduce BP and increase the antioxidant activity in HD patients.
Mar 30, 2015
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2015 Mar 31. Epub 2015 Mar 31. PMID:
25826143
Article Published Date
: Mar 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Chronic Kidney Disease (CKD)
,
Hemodialysis
Pharmacological Actions
:
Antihypertensive Agents
,
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Pomegranate juice augments memory and FMRI activity in middle-aged and older adults with mild memory complaints.
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: Evid Based Complement Alternat Med. 2013 ;2013:946298. Epub 2013 Jul 22. PMID:
23970941
Article Published Date
: Dec 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Cognitive Decline/Dysfunction
,
Memory Loss
Pharmacological Actions
:
Ergogenic
[+]
Pomegranate juice confers a lower glycemic response on a high-glycemic index food.
Oct 10, 2017
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2017 Oct 11. Epub 2017 Oct 11. PMID:
29021286
Article Published Date
: Oct 10, 2017
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
,
Punicalagin
Diseases
:
Hyperglycemia
Pharmacological Actions
:
Hypoglycemic Agents
[+]
Pomegranate juice consumption appears to slow the progression of the carotid intima-media thickness in subjects with increased oxidative stress and poor blood lipid profiles.
Oct 01, 2009
Click here to read the entire abstract
Pubmed Data
: Am J Cardiol. 2009 Oct 1;104(7):936-42. PMID:
19766760
Article Published Date
: Oct 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
,
Pomegranate
Diseases
:
Arterial Thickening
,
Carotid Artery Narrowing
,
Intima Media Thickening
Pharmacological Actions
:
Anti-atherogenic
,
Antioxidants
[+]
Pomegranate juice consumption could decrease systolic and diastolic blood pressure in patients with diabetes.
Jan 31, 2019
Click here to read the entire abstract
Pubmed Data
: Clin Nutr ESPEN. 2019 Feb ;29:30-35. Epub 2018 Dec 20. PMID:
30661697
Article Published Date
: Jan 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Diabetes Mellitus: Type 2
,
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
[+]
Pomegranate juice consumption has potential anti-inflammatory and cardio-protective effects.
Jul 31, 2016
Click here to read the entire abstract
Pubmed Data
: J Sci Food Agric. 2016 Aug 1. Epub 2016 Aug 1. PMID:
27476699
Article Published Date
: Jul 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Lipid Peroxidation
,
Metabolic Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Malondialdehyde Down-regulation
[+]
Pomegranate juice consumption may delay onset of T2D complications related to oxidative stress.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Nutr Res. 2015 ;59:28551. Epub 2015 Sep 8. PMID:
26355954
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Diabetes: Oxidative Stress
,
Diabetes Mellitus: Type 2
,
Lipid Peroxidation
Pharmacological Actions
:
Antioxidants
[+]
Pomegranate juice could attenuate oxidative stress following an intensive weightlifting training session.
Jul 28, 2017
Click here to read the entire abstract
Pubmed Data
: Nutrients. 2017 Jul 29 ;9(8). Epub 2017 Jul 29. PMID:
28758938
Article Published Date
: Jul 28, 2017
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Oxidative Stress
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Antioxidants
[+]
Pomegranate juice could have favourable effects on oxidative stress in patients with type 2 diabetes.
Sep 15, 2016
Click here to read the entire abstract
Pubmed Data
: Int J Food Sci Nutr. 2016 Sep 16:1-7. Epub 2016 Sep 16. PMID:
27633135
Article Published Date
: Sep 15, 2016
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Diabetes Mellitus: Type 2
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
Pomegranate juice had beneficial effects on hormonal biomarkers of breast cancer risk in this preliminary study.
Sep 30, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2015 Oct ;67(7):1113-9. Epub 2015 Sep 1. PMID:
26327495
Article Published Date
: Sep 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Breast Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
Pomegranate juice has potent antiatherogenic effects in healthy humans and in atherosclerotic mice that may be attributable to its antioxidative properties.
May 01, 2000
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Clin Nutr. 2000 May ;71(5):1062-76. PMID:
10799367
Article Published Date
: May 01, 2000
Study Type
: Animal Study, Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Arteriosclerosis
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Cardiotonic Agents
[+]
Pomegranate juice improves the cardiometabolic risk factors, biomarkers of oxidative stress and inflammation in hemodialysis patients.
Oct 22, 2019
Click here to read the entire abstract
Pubmed Data
: J Sci Food Agric. 2019 Oct 23. Epub 2019 Oct 23. PMID:
31646650
Article Published Date
: Oct 22, 2019
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Hemodialysis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
[+]
Pomegranate juice increases sirtuin1 protein in peripheral blood mononuclear cell from patients with type 2 diabetes.
Jun 28, 2018
Click here to read the entire abstract
Pubmed Data
: Metab Syndr Relat Disord. 2018 Jun 29. Epub 2018 Jun 29. PMID:
29957104
Article Published Date
: Jun 28, 2018
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Pomegranate juice intake enhances the effects of aerobic training on insulin resistance and liver enzymes in type 2 diabetic men.
May 16, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Nutr. 2022 May 17 ;8(1):48. Epub 2022 May 17. PMID:
35581639
Article Published Date
: May 16, 2022
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Diabetes Mellitus: Type 2
,
Insulin Resistance
Therapeutic Actions
:
Exercise: Aerobic
Pharmacological Actions
:
Enzyme Inhibitors
[+]
Pomegranate juice intake had a significant beneficial effect, lowering systolic blood pressure and improving the lipid profiles of hemodialysis patients.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr J. 2014 ;13:18. Epub 2014 Mar 4. PMID:
24593225
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Atherosclerosis
,
Cardiovascular Diseases
,
Hypertension
,
Kidney Failure
,
Oxidative Stress
,
Triglycerides: Elevated
Pharmacological Actions
:
Anti-atherogenic
,
Anti-Inflammatory Agents
,
Antihypertensive Agents
,
Antioxidants
,
Cardiovascular Agents
Additional Keywords
:
Phytotherapy
[+]
Pomegranate juice prolongs PSA doubling time, inhibits cell proliferation and increases apoptosis in men with prostate cancer.
Feb 01, 2007
Click here to read the entire abstract
Pubmed Data
: Forsch Komplementmed. 2007 Feb;14(1):39-44. Epub 2007 Mar 6. PMID:
16818701
Article Published Date
: Feb 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Prostate: PSA Doubling
,
Prostate Cancer
[+]
Pomegranate juice significantly modulates matrix metalloproteinases 2 and 9 and serum levels of inflammatory factors protecting against exercise induced oxidative injury.
Jun 30, 2014
Click here to read the entire abstract
Pubmed Data
: J Pak Med Assoc. 2014 Jul ;64(7):785-90. PMID:
25255587
Article Published Date
: Jun 30, 2014
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Anti Inflammatory
,
Antioxidants
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Phytotherapy
,
Prolonged Exercise
[+]
Pomegranate peel extract seems effective in complementary management of ulcerative colitis.
Jul 31, 2015
Click here to read the entire abstract
Pubmed Data
: Complement Ther Clin Pract. 2015 Aug ;21(3):141-6. Epub 2015 Apr 1. PMID:
26256131
Article Published Date
: Jul 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Ulcerative Colitis
Additional Keywords
:
Plant Extracts
[+]
Pomegranate polyphenols enhanced cognitive and functional recovery after stroke.
Feb 12, 2018
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2018 Feb 13:1-6. Epub 2018 Feb 13. PMID:
29433376
Article Published Date
: Feb 12, 2018
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Stroke: Attenuation/Recovery
Pharmacological Actions
:
Neuroprotective Agents
[+]
Pomegranate reduces the intima media thickness size of the artery, while also reducing blood pressure and LDL oxidation.
Jun 01, 2004
Click here to read the entire abstract
Pubmed Data
: Clin Nutr. 2004 Jun;23(3):423-33. PMID:
15158307
Article Published Date
: Jun 01, 2004
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Carotid Stenosis
,
Cholesterol: Oxidation
,
Hypertension
,
Intima Media Thickening
[+]
Pomegranate seed oil increased the GLUT-4 gene expression in diabetic patients without any side effects.
Apr 02, 2019
Click here to read the entire abstract
Pubmed Data
: J Cell Physiol. 2019 Apr 3. Epub 2019 Apr 3. PMID:
30945297
Article Published Date
: Apr 02, 2019
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Hypoglycemic Agents
[+]
Pomegranate seed oil influenced significant improvements in patients with menopausal symptoms.
Feb 28, 2017
Click here to read the entire abstract
Pubmed Data
: Altern Ther Health Med. 2017 Mar ;23(2):28-34. PMID:
28323626
Article Published Date
: Feb 28, 2017
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate Seed
Diseases
:
Menopausal Syndrome
Additional Keywords
:
Plant Oils
[+]
Pomegranate supplementation accelerates recovery of muscle damage and soreness and inflammatory markers.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2016 ;11(10):e0160305. Epub 2016 Aug 20. PMID:
27764091
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Muscle Soreness: Exercise-Induced
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
[+]
POMx alleviates disease activity and improves some blood biomarkers of inflammation and oxidative stress in rheumatoid arthritis patients.
Aug 30, 2016
Click here to read the entire abstract
Pubmed Data
: Eur J Clin Nutr. 2016 Aug 31. Epub 2016 Aug 31. PMID:
27577177
Article Published Date
: Aug 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
POMx treatment significantly increased the PSA doubling time by over 6 months in both treatment arms.
May 19, 2011
Click here to read the entire abstract
Pubmed Data
: J Clin Oncol. 2011 May 20 ;29(15_suppl):4522. PMID:
28023432
Article Published Date
: May 19, 2011
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Prostate Cancer
Additional Keywords
:
Cancer
,
Plant Extracts
,
pomegranate
,
POMx
,
prostate cancer
[+]
POMx treatment significantly increased the PSA doubling time by over 6 months in men with prostate cancer.
Feb 28, 2011
Click here to read the entire abstract
Pubmed Data
: J Clin Oncol. 2011 Mar ;29(7_suppl):11. PMID:
27968310
Article Published Date
: Feb 28, 2011
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Prostate Cancer
Additional Keywords
:
Plant Extracts
[+]
Protective effect of Punica granatum extract in head and neck cancer patients undergoing radiotherapy.
Sep 30, 2019
Click here to read the entire abstract
Pubmed Data
: Indian J Otolaryngol Head Neck Surg. 2019 Oct ;71(Suppl 1):318-320. Epub 2018 Mar 15. PMID:
31741979
Article Published Date
: Sep 30, 2019
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Chemotherapy and Radiation Toxicity
,
Head and Neck Cancer
,
Radiation Induced Illness: Mucositis
Pharmacological Actions
:
Radioprotective
[+]
Punica granatum peel extract as adjunct irrigation to nonsurgical treatment of chronic gingivitis.
Apr 30, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Complement Ther Clin Pract. 2021 May ;43:101383. Epub 2021 Apr 2. PMID:
33862350
Article Published Date
: Apr 30, 2021
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Gingivitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
Additional Keywords
:
Plant Extracts
[+]
Safety: pomegranate juice does not adversely affect insulin sensitivity and contributes to reduction in weight gain.
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: Ann Nutr Metab. 2011 ;58(3):220-3. Epub 2011 Jul 28. PMID:
21811060
Article Published Date
: Jan 01, 2011
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Insulin Resistance
,
Overweight
[+]
Short-term consumption of pomegranate juice alleviates some metabolic disturbances in overweight patients with dyslipidemia.
Jan 31, 2021
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2021 Feb 1. Epub 2021 Feb 1. PMID:
33523763
Article Published Date
: Jan 31, 2021
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Dyslipidemias
,
Overweight
Pharmacological Actions
:
Hypolipidemic
[+]
Supplementation with pomegranate contributed to a significant strengthening of plasma antioxidant potential in the group of well-trained rowers.
Jul 23, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Int Soc Sports Nutr. 2018 Jul 24 ;15(1):35. Epub 2018 Jul 24. PMID:
30041701
Article Published Date
: Jul 23, 2018
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Oxidative Stress
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Antioxidants
[+]
The addition of POMx to simvastatin therapy in hypercholesterolemic patients improved oxidative stress and lipid status in the patient's serum and in their HMDM.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: Atherosclerosis. 2014 Jan ;232(1):204-10. Epub 2013 Nov 19. PMID:
24401239
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Atherosclerosis
,
High Cholesterol
,
Oxidative Stress
,
Triglycerides: Elevated
Pharmacological Actions
:
Anti-atherogenic
,
Antioxidants
,
Hypolipidemic
Additional Keywords
:
Natural Substance/Drug Synergy
,
Plant Extracts
Problem Substances
:
Simvastatin
,
Statin Drugs
[+]
The aqueous extracts of the chosen herbal plants showed an acceptable antibacterial efficacy against oral streptococci.
Oct 30, 2017
Click here to read the entire abstract
Pubmed Data
: J Clin Pediatr Dent. 2017 Oct 31. Epub 2017 Oct 31. PMID:
29087796
Article Published Date
: Oct 30, 2017
Study Type
: Human Study
Additional Links
Substances
:
Grape Seed Extract
,
Guava
,
Pomegranate
Diseases
:
Streptococcus Infections
Pharmacological Actions
:
Anti-Bacterial Agents
Additional Keywords
:
Mouthwash
,
Plant Extracts
[+]
The combined formulation of fruit extracts showed excellent antioxidative and anti-collagenase activity as well as a significant effect on anti-wrinkle activity on human skin.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Clin Cosmet Investig Dermatol. 2015 ;8:389-96. Epub 2015 Jul 16. PMID:
26203268
Article Published Date
: Dec 31, 2014
Study Type
: Human Study, In Vitro Study
Additional Links
Substances
:
Fig
,
Ginkgo biloba
,
Pomegranate
,
White Mulberry
Diseases
:
Aging Skin
,
Wrinkles
Pharmacological Actions
:
Anti-collagenase
,
Antioxidants
Additional Keywords
:
Dose Response
,
Natural Substances Versus Drugs
,
Plant Extracts
[+]
The daily consumption of fermented pomegranate extracts can protect the skin against oxidative stress and slow skin aging.
Aug 19, 2021
Click here to read the entire abstract
Pubmed Data
: J Cosmet Dermatol. 2021 Aug 20. Epub 2021 Aug 20. PMID:
34416060
Article Published Date
: Aug 19, 2021
Study Type
: Human Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Pomegranate
Diseases
:
Aging Skin
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
The effect of a citrus and pomegranate complex on physical fitness and mental well-being in healthy elderly.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Nutr Health Aging. 2022 ;26(9):839-846. PMID:
36156675
Article Published Date
: Dec 31, 2021
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Grapefruit
,
Lemon
,
Orange
,
Pomegranate
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
[+]
The effect of concentrated pomegranate juice consumption on risk factors of cardiovascular diseases in women with polycystic ovary syndrome.
Aug 06, 2020
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2020 Aug 7. Epub 2020 Aug 7. PMID:
32767710
Article Published Date
: Aug 06, 2020
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Cardiovascular Diseases
,
Polycystic Ovary Syndrome
Pharmacological Actions
:
Antihypertensive Agents
[+]
The effect of pomegranate extract on anthropometric indices, serum lipids, glycemic indicators, and blood pressure in patients with NAFLD.
Sep 07, 2021
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2021 Sep 8. Epub 2021 Sep 8. PMID:
34498307
Article Published Date
: Sep 07, 2021
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Antihypertensive Agents
,
Hypoglycemic Agents
,
Hypolipidemic
[+]
The effect of pomegranate juice and sumac consumption in the treatment of outpatients with COVID-19.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mediators Inflamm. 2022 ;2022:6850342. Epub 2022 Nov 30. PMID:
36505757
Article Published Date
: Dec 31, 2021
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
,
Sumac
Diseases
:
Coronavirus Infection
Additional Keywords
:
Significant Treatment Outcome
[+]
The results of this study suggest protective effects of pomegranate juice against myocardial ischemia and reperfusion injury.
Sep 14, 2017
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2017 Sep 15. Epub 2017 Sep 15. PMID:
28913846
Article Published Date
: Sep 14, 2017
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Angina Pectoris
,
Myocardial Ischemia
Pharmacological Actions
:
Cardioprotective
Additional Keywords
:
Risk Reduction
[+]
A Polyphenol-rich pomegranate fruit extract suppresses NF-κB and IL-6 expression.
Mar 08, 2017
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2017 Mar 9. Epub 2017 Mar 9. PMID:
28276100
Article Published Date
: Mar 08, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Pomegranate
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chondroprotective
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
P. granatum extracts had cytotoxic and apoptotic effects on human U266 multiple myeloma cells via disruption of mitochondrial membrane potential and increasing cell cycle arrest.
Aug 28, 2015
Click here to read the entire abstract
Pubmed Data
: Tumour Biol. 2015 Aug 29. Epub 2015 Aug 29. PMID:
26318303
Article Published Date
: Aug 28, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Pomegranate
Diseases
:
Multiple Myeloma
Pharmacological Actions
:
Apoptotic
,
Cell cycle arrest
,
Chemopreventive
,
Cytotoxic
Additional Keywords
:
Plant Extracts
[+]
Pomegranate juice attenuated the damaging effects of cigarette smoke on cultured human alveolar cells.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Chron Obstruct Pulmon Dis. 2016 ;11:227-37. Epub 2016 Feb 3. PMID:
26893554
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Pomegranate
Diseases
:
Inflammation
,
Lung Injury: Smoke-Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Pomegranate juice is able to attenuate the damage provoked by cigarette smoke on cultured human alveolar macrophages.
Sep 26, 2016
Click here to read the entire abstract
Pubmed Data
: Endocr Metab Immune Disord Drug Targets. 2016 Sep 27. Epub 2016 Aug 27. PMID:
27697073
Article Published Date
: Sep 26, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Pomegranate
Diseases
:
Lung Injury: Smoke-Induced
,
Tobacco Toxicity
Pharmacological Actions
:
Cytoprotective
[+]
The minimum inhibitory concentration of peel extract of Punica granatum approximated with that of the clotrimazole.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Diagn Res. 2017 Jan ;11(1):ZC114-ZC117. Epub 2017 Jan 1. PMID:
28274059
Article Published Date
: Dec 31, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Candidiasis
Pharmacological Actions
:
Antifungal Agents
Additional Keywords
:
Natural Substances Versus Drugs
[+]
Pomegranate extract affects gut biofilm forming bacteria and promotes intestinal mucosal healing.
Apr 04, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2023 Apr 5 ;15(7). Epub 2023 Apr 5. PMID:
37049615
Article Published Date
: Apr 04, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Colitis
,
Inflammatory Bowel Diseases
,
Wound Healing
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
[+]
Punicalagin might find good use in wound healing therapy.
Aug 21, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2016 Aug 22 ;21(8). Epub 2016 Aug 22. PMID:
27556440
Article Published Date
: Aug 21, 2016
Study Type
: Human: Case Report
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Wound Healing
Additional Keywords
:
Pomegranate Peel
,
punicalagin
,
wound healing
[+]
These observations showed that pomegranate flower polyphenol ameliorates vasodilation in hyperglycemic rats.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2022 ;2022:4158762. Epub 2022 Jun 8. PMID:
35722136
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Pomegranate flower
Diseases
:
Diabetic Complications
,
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
,
Antioxidants
[+]
"Pomegranate (Punica granatum L.) flower improves learning and memory performances impaired by diabetes mellitus in rats."
Dec 01, 2011
Click here to read the entire abstract
Pubmed Data
: Acta Physiol Hung. 2011 Dec ;98(4):409-20. PMID:
22173022
Article Published Date
: Dec 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Diabetes: Cognitive Dysfunction
[+]
"Pomegranate Extract Attenuates Gentamicin-Induced Nephrotoxicity in Rats by Reducing Oxidative Stress."
Nov 25, 2012
Click here to read the entire abstract
Pubmed Data
: Ren Fail. 2012 Nov 26. Epub 2012 Nov 26. PMID:
23176634
Article Published Date
: Nov 25, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Chemotherapy-Induced Toxicity: Gentamicin
,
Kidney Damage: Chemically-Induced
Pharmacological Actions
:
Antioxidants
,
Renoprotective
Additional Keywords
:
Drug: Gentamicin
Problem Substances
:
Gentamicin
Adverse Pharmacological Actions
:
Nephrotoxic
[+]
A combination of black bean peel and pomegranate peel extracts, have the ability to ameliorate hyperglycemia by inhibiting oxidative stress induced damage to the pancreas.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2015 Jan ;9(1):43-48. Epub 2014 Oct 30. PMID:
25452774
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Beans: All
,
Black Bean
,
Pomegranate Peel
Diseases
:
Diabetes
,
Diabetes: Oxidative Stress
,
Hyperglycemia
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Natural Substance Synergy
,
Plant Extracts
[+]
A combination of pomegranate, date fruit and date seeds led to a more potent treatment result than each alone.
Mar 25, 2015
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2015 Mar 26. Epub 2015 Mar 26. PMID:
25811166
Article Published Date
: Mar 25, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Dates
,
Polyphenols
,
Pomegranate
Diseases
:
Atherosclerosis
,
Oxidative Stress
,
Triglycerides: Elevated
Pharmacological Actions
:
Anti-atherogenic
,
Anticholesteremic Agents
,
Antioxidants
Additional Keywords
:
Natural Substance Synergy
[+]
A herbal mixture from propolis, pomegranate, and grape pomace endowed with anti-inflammatory activity in an in vivo rheumatoid arthritis model.
May 10, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2020 May 11 ;25(9). Epub 2020 May 11. PMID:
32403241
Article Published Date
: May 10, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Grape
,
Pomegranate
,
Propolis: Bee
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-17 downregulation
,
Interleukin-1 beta downregulation
[+]
A methanolic extract of pomegranate peel ameliorated the hepatic damage caused by acetaminophen.
Jun 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Pak Med Assoc. 2016 Jul ;66(7):859-63. PMID:
27427136
Article Published Date
: Jun 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Acetaminophen (Tylenol) Toxicity
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
A nanoformulation of pomegranate seed oil can delay disease onset in a mouse model of genetic prion diseases.
Jul 31, 2014
Click here to read the entire abstract
Pubmed Data
: Nanomedicine. 2014 Aug ;10(6):1353-63. Epub 2014 Apr 2. PMID:
24704590
Article Published Date
: Jul 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Alzheimer's Disease
,
Creutzfeldt-Jakob disease
,
Lipid Peroxidation
,
Neurodegenerative Diseases
,
Prion Diseases
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
A polysaccharide from Punica granatum has an inhibitory effect on metastasis.
May 24, 2017
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2017 May 25. Epub 2017 May 25. PMID:
28552725
Article Published Date
: May 24, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Cancer Metastasis
,
Lung Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
Additional Keywords
:
Anti-metastatic
,
Cancer Metastasis
,
Lung Cancer: Metastatic
,
pomegranate
[+]
A pomegranate flower extract could ameliorate gentamicin induced renal toxicity in male rats.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Renal Inj Prev. 2015 ;4(2):45-50. Epub 2015 Jun 1. PMID:
26060837
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate flower
Diseases
:
Chemotherapy-Induced Toxicity: Gentamicin
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
Additional Keywords
:
Plant Extracts
[+]
A standardized pomegranate fruit extract ameliorates thioacetamide-induced liver fibrosis.
Feb 28, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Heliyon. 2023 Mar ;9(3):e14256. Epub 2023 Mar 4. PMID:
36938469
Article Published Date
: Feb 28, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
[+]
Administration of pomegranate peel extract has neuroprotective effects involving multiple mechanisms.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2016 ;11(11):e0166123. Epub 2016 Nov 9. PMID:
27829013
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Alzheimer's Disease
,
Lipid Peroxidation
,
Neurodegenerative Diseases
Pharmacological Actions
:
Malondialdehyde Down-regulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Alleviation of cyclophosphamide-induced hemorrhagic cystitis by dietary pomegranate.
May 03, 2018
Click here to read the entire abstract
Pubmed Data
: J Pediatr Hematol Oncol. 2018 May 4. Epub 2018 May 4. PMID:
29734214
Article Published Date
: May 03, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Cystitis: Hemorrhagic
Pharmacological Actions
:
Chemoprotective Agents
[+]
Amelioration of oxidative stress, cholinergic dysfunction, and neuroinflammation in scopolamine-induced amnesic rats fed with pomegranate seed.
Mar 27, 2022
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2022 Mar 28. Epub 2022 Mar 28. PMID:
35348947
Article Published Date
: Mar 27, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Brain: Oxidative Stress
,
Brain Inflammation
,
Memory Disorders
Pharmacological Actions
:
Neuroprotective Agents
[+]
An aqueous extract of pomegranate alone or in combination with citalopram produces antidepressant-like effects.
Dec 18, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2017 Dec 19 ;18(12). Epub 2017 Dec 19. PMID:
29257042
Article Published Date
: Dec 18, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Depression: Postmenopausal
Pharmacological Actions
:
Antidepressive Agents
[+]
An ellagic acid enriched pomegranates extract promoted cholesterol removal by enhancing fecal bile acid.
Feb 28, 2015
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2015 Mar ;6(3):780-7. PMID:
25579987
Article Published Date
: Feb 28, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ellagic Acid
,
Pomegranate
Diseases
:
Hyperlipidemia
Additional Keywords
:
Plant Extracts
,
Superiority of Natural Substances versus Drugs
Problem Substances
:
Simvastatin
[+]
Antenatal pomegranate juice rescues hypoxia-induced fetal growth restriction in pregnant mice.
May 31, 2018
Click here to read the entire abstract
Pubmed Data
: Placenta. 2018 Jun ;66:1-7. Epub 2018 Apr 16. PMID:
29884297
Article Published Date
: May 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Hypoxia
,
Pregnancy Complications
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
[+]
Anthocyanins rich pomegranate cream as a topical formulation with anti-aging activity.
Feb 04, 2020
Click here to read the entire abstract
Pubmed Data
: J Dermatolog Treat. 2020 Feb 5:1-8. Epub 2020 Feb 5. PMID:
32022625
Article Published Date
: Feb 04, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Pomegranate
Diseases
:
Aging Skin
Pharmacological Actions
:
Antioxidants
[+]
Anti-climacterium effects of pomegranate concentrated solutions in ovariectomized ddY mice.
Mar 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2017 Apr ;13(4):1249-1266. Epub 2017 Feb 8. PMID:
28413464
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Hepatic Steatosis
,
Hyperlipidemia
,
Obesity
,
Osteoporosis
Additional Keywords
:
Ovariectomy-Induced Changes
,
Risk Reduction
[+]
Anti-inflammatory mechanisms could be involved in pomegranate-mediated prevention of breast cancer.
Apr 27, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Apr 28 ;9(5). Epub 2017 Apr 28. PMID:
28452959
Article Published Date
: Apr 27, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
Heat Shock Protein Down-Regulation
[+]
Antinociceptive synergism of pomegranate peel extract and acetylsalicylic acid in an animal pain model.
Sep 06, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2021 Sep 7 ;26(18). Epub 2021 Sep 7. PMID:
34576905
Article Published Date
: Sep 06, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Chronic Pain
Pharmacological Actions
:
Antinoceceptive
Additional Keywords
:
Natural Substance Synergy
[+]
Aqueous extract of pomegranate enriched in ellagitannins prevents anxiety-like behavior.
Nov 30, 2020
Click here to read the entire abstract
Pubmed Data
: Neurochem Int. 2020 Dec ;141:104876. Epub 2020 Oct 10. PMID:
33049337
Article Published Date
: Nov 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Anxiety
,
Menopausal Syndrome
Pharmacological Actions
:
Anti-Anxiety Agents
Anti Therapeutic Actions
:
Western Diet
[+]
Astragalus membranaceus and Punica granatum alleviate infertility and kidney dysfunction induced by aging in male rats.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Turk J Biol. 2020 ;44(4):166-175. Epub 2020 Aug 19. PMID:
32922124
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
,
TA-65 (Astragalus compound)
Diseases
:
Aging
,
Infertility: Male
,
Kidney Damage
Pharmacological Actions
:
Fertility Agents: Male
,
Renoprotective
[+]
Beneficial effect of Punica granatum peel extract on murine malaria-induced spleen injury.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2016 ;16(1):221. Epub 2016 Jul 16. PMID:
27422638
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Malaria
Pharmacological Actions
:
Antimalarials
[+]
Carvacrol and pomegranate decrease methotrexate related damage and apoptotic activity in intestinal tissue.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Clin Exp Med. 2015;8(9):15474-15481. Epub 2015 Sep 15. PMID:
26629037
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
,
Pomegranate
Diseases
:
Drug-Induced Toxicity: Methotrexate
Pharmacological Actions
:
Anti-Apoptotic
,
Gastroprotective
[+]
Cellular damage induced by lead in the tissues of the kidney, liver and the heart were observed to have been partially prevented by pomegranate juice.
Oct 30, 2017
Click here to read the entire abstract
Pubmed Data
: Cell Mol Biol (Noisy-le-grand). 2017 Oct 31 ;63(10):33-42. Epub 2017 Oct 31. PMID:
29096741
Article Published Date
: Oct 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Lead Poisoning
Pharmacological Actions
:
Cardioprotective
,
Hepatoprotective
,
Renoprotective
[+]
Chemical characteristics, antioxidant capacities and hepatoprotection of polysaccharides from pomegranate peel.
Dec 14, 2018
Click here to read the entire abstract
Pubmed Data
: Carbohydr Polym. 2018 Dec 15 ;202:461-469. Epub 2018 Sep 7. PMID:
30287023
Article Published Date
: Dec 14, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Polysaccharides
[+]
Chronic stress could increase the severity of carcinogenesis and also diminishes the anti-oxidative efficacy of pomegranate juice.
Nov 22, 2015
Click here to read the entire abstract
Pubmed Data
: Tumour Biol. 2015 Nov 23. Epub 2015 Nov 23. PMID:
26596837
Article Published Date
: Nov 22, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Oxidative Stress
,
Stress
Pharmacological Actions
:
Antioxidants
,
Chemopreventive
[+]
Combination of pomegranate extract and curcumin ameliorates thioacetamide-induced liver fibrosis.
Jul 26, 2020
Click here to read the entire abstract
Pubmed Data
: Toxicol Mech Methods. 2020 Jul 27:1-23. Epub 2020 Jul 27. PMID:
32718261
Article Published Date
: Jul 26, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Pomegranate
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
[+]
Combinations of pomegranate with each of VIN, propolis, or cocoa have a promising disease-modifying antiparkinsonian therapy.
Aug 11, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Aging Res. 2021 Aug 12:1-20. Epub 2021 Aug 12. PMID:
34384037
Article Published Date
: Aug 11, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Cocoa
,
Pomegranate
,
Propolis: Bee
Diseases
:
Parkinson's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Consumption of pomegranate peel extract may be effective in preventing the bone loss.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2015 ;7(11):9265-84. Epub 2015 Nov 11. PMID:
26569295
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Osteogenic
Additional Keywords
:
Plant Extracts
[+]
Consumption of pomegranates improves synaptic function in a transgenic mice model of Alzheimer's disease.
Jul 27, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Jul 28. Epub 2016 Jul 28. PMID:
27486879
Article Published Date
: Jul 27, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Dietary ellagitannins from pomegranate could alleviate intestinal mucositis in rats induced by 5-FU.
Jun 18, 2018
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2018 Jun 19. Epub 2018 Jun 19. PMID:
29920075
Article Published Date
: Jun 18, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
,
Colorectal Cancer
Pharmacological Actions
:
Chemoprotective Agents
,
Chemosensitizer
Additional Keywords
:
Chemothapeutic Synergy: 5-flourouracil
[+]
Dietary pomegranate supplement alleviates murine pancreatitis.
Dec 20, 2018
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2018 Dec 21 ;66:17-28. Epub 2018 Dec 21. PMID:
30708236
Article Published Date
: Dec 20, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Pancreatitis
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Nrf2 activation
,
Pancreato Protective Agents
[+]
Diets containing pomegranate polyphenol and soy isoflavone attenuate contact hypersensitivity in mice.
Feb 28, 2019
Click here to read the entire abstract
Pubmed Data
: Biosci Biotechnol Biochem. 2019 Mar ;83(3):525-530. Epub 2018 Nov 10. PMID:
30417760
Article Published Date
: Feb 28, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Isoflavones
,
Pomegranate
Diseases
:
Dermatitis: Contact
[+]
Effects of pomegranate peel polyphenols combined with inulin on gut microbiota and serum metabolites of high-fat-induced obesity.
Apr 11, 2023
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2023 Apr 12 ;71(14):5733-5744. Epub 2023 Mar 30. PMID:
36996454
Article Published Date
: Apr 11, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Polyphenols
,
Pomegranate Peel
Diseases
:
High Fat Diet
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Efficacy of pomegranate extract loaded solid lipid nanoparticles transdermal emulgel against Ehrlich ascites carcinoma.
Sep 25, 2021
Click here to read the entire abstract
Pubmed Data
: Nanomedicine. 2021 Sep 26:102466. Epub 2021 Sep 26. PMID:
34587542
Article Published Date
: Sep 25, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Ehrlich carcinoma
Pharmacological Actions
:
Chemotherapeutic
[+]
Ellagic acid application could be a useful memory restorative agent in the treatment of dementia seen in elderly persons.
Jan 31, 2016
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2016 Feb 1:1-7. Epub 2016 Feb 1. PMID:
26828763
Article Published Date
: Jan 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ellagic Acid
,
Pomegranate
Diseases
:
Cognitive Decline/Dysfunction
,
Dementia
,
Memory Disorders
,
Memory Disorders: Drug-Induced
Pharmacological Actions
:
Neuroprotective Agents
[+]
Evaluating the potential role of pomegranate peel in aluminum-induced oxidative stress and histopathological alterations in brain of female rats.
Nov 30, 2012
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2012 Dec ;150(1-3):328-36. Epub 2012 Sep 5. PMID:
22945624
Article Published Date
: Nov 30, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
,
Pomegranate Peel
Diseases
:
Aluminum Toxicity
,
Neurodegenerative Diseases
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Evaluation of the effect of pomegranate seed oil on healing in a rat wound model.
Aug 30, 2021
Click here to read the entire abstract
Pubmed Data
: Int J Low Extrem Wounds. 2021 Aug 31:15347346211040593. Epub 2021 Aug 31. PMID:
34463139
Article Published Date
: Aug 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Wound Healing
Pharmacological Actions
:
Antioxidants
[+]
Evaluation of wound healing potential of pomegranate whole fruit extract on skin burn wounds.
May 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Adv Vet Anim Res. 2019 Jun ;6(2):202-207. Epub 2019 Apr 14. PMID:
31453192
Article Published Date
: May 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Burns
,
Wound Healing
Pharmacological Actions
:
Anti-Bacterial Agents
,
Anti-Inflammatory Agents
,
Antioxidants
[+]
Extracts of pomegranate peels and seeds have protective effects against liver fibrosis induced by carbon tetrachloride.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2015 ;15(1):389. Epub 2015 Oct 27. PMID:
26508316
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
,
Pomegranate Seed
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Extracts rich in gallo- and ellagitannins act on different molecular targets in the protection against ulcerative colitis.
Mar 28, 2016
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2016 Mar 29. Epub 2016 Mar 29. PMID:
27028006
Article Published Date
: Mar 28, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Mango
,
Pomegranate
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
[+]
F. carica extract is more effective than L. sativum and P. granatum extracts in the prevention and control of type 2 diabetes mellitus (T2DM) and its consequences.
Dec 31, 2020
Click here to read the entire abstract
Pubmed Data
: J Diabetes Res. 2021 ;2021:6018835. Epub 2021 Dec 21. PMID:
34970629
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Fig
,
Garden Cress (Lepidium sativum)
,
Pomegranate
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Hypoglycemic Agents
[+]
Gastro-protective and therapeutic effect of Punica granatum against stomach ulcer caused by Helicobacter pylori.
Jan 30, 2023
Click here to read the entire abstract
Pubmed Data
: Cell Mol Biol (Noisy-le-grand). 2023 Jan 31 ;69(1):48-53. Epub 2023 Jan 31. PMID:
37213156
Article Published Date
: Jan 30, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Gastric Ulcer
,
Helicobacter Pylori Infection
Pharmacological Actions
:
Anti-Ulcer Agents
,
Gastroprotective
Additional Keywords
:
Superiority of Natural Substances versus Drugs
[+]
Healthy properties of a new formulation of pomegranate-peel extract in mice suffering from experimental autoimmune encephalomyelitis.
Jan 27, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2022 Jan 28 ;27(3). Epub 2022 Jan 28. PMID:
35164175
Article Published Date
: Jan 27, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Encephalomyelitis
,
Multiple Sclerosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Hepatoprotective potential of pomegranate in curbing the incidence of acute liver injury.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2021 ;12:694607. Epub 2021 Nov 26. PMID:
34899284
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Hepatitis
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
High-dose berberine ameliorated cigarette smoke extract-induced airway inflammation in COPD mice.
Sep 30, 2019
Click here to read the entire abstract
Pubmed Data
: Curr Med Sci. 2019 Oct ;39(5):748-753. Epub 2019 Oct 14. PMID:
31612392
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Chronic Obstructive Pulmonary Disease
,
Lung Injury: Smoke-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Hypocholesterolemic effects of expeller-pressed and solvent-extracted fruit seed oils and defatted pomegranate seed meals.
Jun 04, 2019
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2019 Jun 5 ;67(22):6150-6159. Epub 2019 May 22. PMID:
31117552
Article Published Date
: Jun 04, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Hypercholesterolemia
Pharmacological Actions
:
Anticholesteremic Agents
,
Hypolipidemic
[+]
Ingestion of pomegranate polyphenols is associated with inhibition of x-ray-induced genomic instability and elevated GSH.
Sep 26, 2016
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2016 Sep 27:1-8. Epub 2016 Aug 27. PMID:
27673354
Article Published Date
: Sep 26, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Polyphenols
,
Pomegranate
Diseases
:
DNA damage
Pharmacological Actions
:
Genoprotective
,
Radioprotective
Anti Therapeutic Actions
:
X-ray Diagnostic Technologies
[+]
Inhibition of oxidative stress, IL-13, and WNT/β-catenin in ovalbumin-sensitized rats by a novel organogel of Punica granatum seed oil saponifiable fraction.
Sep 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2022 Oct ;154:113667. Epub 2022 Sep 7. PMID:
36942603
Article Published Date
: Sep 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Seed
Diseases
:
Asthma: Bronchial
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
interleukin-13 down-regulation
,
Wnt/β-catenin signaling pathway modulation
[+]
ketoprofen-loaded pomegranate seed oil nanoemulsions presented a high antinociceptive activity in the animal models tested.
Apr 04, 2016
Click here to read the entire abstract
Pubmed Data
: Colloids Surf B Biointerfaces. 2016 Apr 5 ;144:214-221. Epub 2016 Apr 5. PMID:
27088191
Article Published Date
: Apr 04, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Seed
Diseases
:
Inflammation
Pharmacological Actions
:
Antinoceceptive
Additional Keywords
:
Plant Oils
Problem Substances
:
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]
Long-term (15 mo) dietary supplementation with pomegranates from Oman attenuates cognitive and behavioral deficits in a transgenic mice model of Alzheimer's disease.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2015 Jan ;31(1):223-9. Epub 2014 Jun 25. PMID:
25441596
Article Published Date
: Dec 31, 2014
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Maternal dietary supplementation with pomegranate juice is neuroprotective in an animal model of neonatal hypoxic-ischemic brain injury.
May 31, 2005
Click here to read the entire abstract
Pubmed Data
: Pediatr Res. 2005 Jun ;57(6):858-64. Epub 2005 Mar 17. PMID:
15774834
Article Published Date
: May 31, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Brain Hypoxia
,
Brain Ischemia
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Phytotherapy
[+]
Maternal pomegranate juice attenuates maternal inflammation-induced fetal brain injury.
Apr 26, 2018
Click here to read the entire abstract
Pubmed Data
: Am J Obstet Gynecol. 2018 Apr 27. Epub 2018 Apr 27. PMID:
29709511
Article Published Date
: Apr 26, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Fetal Origin of Adult Disease
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Microencapsulated pomegranate peel extract induces mitochondrial complex IV activity and prevents mitochondrial cristae alteration in brown adipose tissue.
Nov 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Nutr. 2020 Dec 1:1-37. Epub 2020 Dec 1. PMID:
33256858
Article Published Date
: Nov 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Obesity
Additional Keywords
:
Anti-Obesity Agents
[+]
Neuroprotective effects of pomegranate juice against Parkinson's disease.
Dec 26, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Mol Sci. 2019 Dec 27 ;21(1). Epub 2019 Dec 27. PMID:
31892167
Article Published Date
: Dec 26, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
,
Urolithin A
Diseases
:
Parkinson's Disease
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
Nitric oxide plays a pivotal role in cardioprotection induced by pomegranate juice against myocardial ischemia and reperfusion.
Sep 30, 2018
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2018 Oct ;32(10):2069-2077. Epub 2018 Jul 12. PMID:
29998575
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Cardioprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Novel pomegranate-nanoparticles ameliorate cisplatin-induced nephrotoxicity and improves cisplatin anti-cancer efficacy.
Feb 27, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2022 Feb 28 ;27(5). Epub 2022 Feb 28. PMID:
35268707
Article Published Date
: Feb 27, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
,
Ehrlich carcinoma
Pharmacological Actions
:
Chemoprotective Agents
,
Chemosensitizer
Additional Keywords
:
Chemotherapeutic Synergy: Cisplatin
[+]
Oral feeding of pomegranate fruit extract inhibits early biomarkers of UVB radiation-induced carcinogenesis.
Nov 01, 2010
Click here to read the entire abstract
Pubmed Data
: Photochem Photobiol. 2010 Nov-Dec;86(6):1318-26. Epub 2010 Oct 14. PMID:
20946358
Article Published Date
: Nov 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Lipid Peroxidation
,
Skin Cancer: Prevention
Therapeutic Actions
:
Sunlight exposure
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Plant Extracts
[+]
P. granatum flower extract promoted wound healing in rats and could be used for managing burn injuries.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Adv Pharmacol Sci. 2017 ;2017:3059745. Epub 2017 Jan 19. PMID:
28203250
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate flower
Diseases
:
Burns
,
Wound Healing
Additional Keywords
:
Plant Extracts
[+]
Phenolic profiles, antihyperglycemic, antihyperlipidemic, and antioxidant properties of pomegranate peel extract.
Mar 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Food Biochem. 2019 Apr ;43(4):e12803. Epub 2019 Feb 11. PMID:
31353600
Article Published Date
: Mar 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Hypoglycemia
Pharmacological Actions
:
Antioxidants
,
Hypoglycemic Agents
,
Hypolipidemic
Additional Keywords
:
Natural Substances Versus Drugs
,
Plant Extracts
[+]
Phytochemical extract from Carica papaya leaves and Punica granatum seeds as therapy against cognitive impairment.
Aug 25, 2023
Click here to read the entire abstract
Pubmed Data
: Mol Neurobiol. 2023 Aug 26. Epub 2023 Aug 26. PMID:
37626269
Article Published Date
: Aug 25, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Papaya
,
Pomegranate
Diseases
:
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
[+]
Polyherbal combination for wound healing: Matricaria chamomilla L. and Punica granatum L.
May 08, 2021
Click here to read the entire abstract
Pubmed Data
: Daru. 2021 May 9. Epub 2021 May 9. PMID:
33966255
Article Published Date
: May 08, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Chamomile
,
Pomegranate
Diseases
:
Wound Healing
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Polyphenols potentiate dietary restriction-induced lifespan extension.
Jan 11, 2012
Click here to read the entire abstract
Pubmed Data
: Biochim Biophys Acta. 2012 Jan 11 ;1822(4):522-526. Epub 2012 Jan 11. PMID:
22265987
Article Published Date
: Jan 11, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
,
Green Tea
,
Polyphenols
,
Pomegranate
Diseases
:
Aging
Therapeutic Actions
:
Fasting/Caloric Restriction
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Pomanox supplementation hinders hyperlipemia-induced coronary endothelial dysfunction by activating the Akt/endothelial nitric oxide-synthase pathway
Feb 28, 2015
Click here to read the entire abstract
Pubmed Data
: Rev Esp Cardiol (Engl Ed). 2015 Mar ;68(3):216-25. Epub 2014 Oct 23. PMID:
25444379
Article Published Date
: Feb 28, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
,
Pomegranate Polyphenols
Diseases
:
Endothelial Dysfunction
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Vasoprotective
Additional Keywords
:
Plant Extracts
[+]
Pomegranate administration downregulated miR-145 levels in alloxan-diabetic wistar rats.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Cell J. 2018 Jan ;19(4):520-527. Epub 2017 Nov 4. PMID:
29105385
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Diabetic Complications
Pharmacological Actions
:
Antioxidants
,
Hypoglycemic Agents
,
MicroRNA modulator
[+]
Pomegranate and its components, punicalagin and ellagic acid, promote antidepressant, antioxidant, and free radical-scavenging activity.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Behav Neurosci. 2022 ;16:836681. Epub 2022 May 6. PMID:
35600992
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ellagic Acid
,
Pomegranate
,
Punicalagin
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
,
Antioxidants
[+]
Pomegranate attenuates inflammation, joint dysfunction via inhibition of NF-κB signaling pathway in experimental models of rheumatoid arthritis.
Jul 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Food Biochem. 2019 Aug ;43(8):e12959. Epub 2019 Jun 17. PMID:
31368549
Article Published Date
: Jul 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Pomegranate by-products could be used in colorectal cancer chemoprevention.
Sep 24, 2017
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2017 Sep 25. Epub 2017 Sep 25. PMID:
28948694
Article Published Date
: Sep 24, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Apoptotic
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
[+]
Pomegranate can be used as a dietary supplement in the treatment of cisplatin-induced kidney injury.
Jun 06, 2016
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2016 Jun 7. Epub 2016 Jun 7. PMID:
27273121
Article Published Date
: Jun 06, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Renoprotective
[+]
Pomegranate could be a potential and efficacious therapeutic agent against liver fibrosis.
Jun 04, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2018 Jun 5 ;8(1):8606. Epub 2018 Jun 5. PMID:
29872102
Article Published Date
: Jun 04, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Liver Fibrosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Pomegranate could be used as a hepatoprotective agent against P. chabaudi-induced hepatic injury.
Dec 14, 2015
Click here to read the entire abstract
Pubmed Data
: Parasitol Res. 2015 Dec 15. Epub 2015 Dec 15. PMID:
26670312
Article Published Date
: Dec 14, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Malaria
Pharmacological Actions
:
Hepatoprotective
[+]
Pomegranate could be used as a supplement to enhance longevity, fertility and growth rate for the other living organisms and human beings.
Mar 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmacogn Mag. 2015 Apr-Jun;11(42):356-9. PMID:
25829775
Article Published Date
: Mar 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Infertility
Pharmacological Actions
:
Antioxidants
,
Fertility Agents
Additional Keywords
:
Dose Response
,
Supplementation
[+]
Pomegranate demonstrated significant cardioprotection against daunorubicin-induced cardiotoxicity.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Prev Med. 2016 ;7:85. Epub 2016 Jun 20. PMID:
27413516
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Cardiotoxicity: Chemotherapy-Induced
,
Chemotherapy and Radiation Toxicity
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Malondialdehyde Down-regulation
[+]
Pomegranate ellagic polyphenols may be a candidate for the treatment of gestational diabetes mellitus.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Am J Transl Res. 2019 ;11(9):5487-5500. Epub 2019 Sep 15. PMID:
31632524
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Polyphenols
,
Pomegranate
Diseases
:
Gestational Diabetes
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Insulin Sensitizers
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Pomegranate exerts hepatoprotective effects against CCl4 induced oxidative stress and liver tissue damage.
Feb 29, 2016
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2016 Mar 1. Epub 2016 Mar 1. PMID:
26936425
Article Published Date
: Feb 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Regenerative
[+]
Pomegranate extract alleviates hypertension by reducing oxidative stress and improving mitochondrial function.
Oct 06, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2016 Oct 7 ;6:34246. Epub 2016 Aug 7. PMID:
27713551
Article Published Date
: Oct 06, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Hypertension
,
Oxidative Stress
Pharmacological Actions
:
Antihypertensive Agents
,
Antioxidants
[+]
Pomegranate extract ameliorates renal ischemia/reperfusion injury.
Nov 30, 2021
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2021 Dec ;40(12_suppl):S573-S582. Epub 2021 Nov 20. PMID:
34802289
Article Published Date
: Nov 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Ischemia
,
Kidney Damage
Pharmacological Actions
:
Renoprotective
[+]
pomegranate extract and beta-sitosterol may be a useful uterine stimulant.
Mar 01, 2010
Click here to read the entire abstract
Pubmed Data
: Reprod Sci. 2010 Mar;17(3):288-96. Epub 2009 Dec 4. PMID:
19966214
Article Published Date
: Mar 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Beta Sitosterol
,
Pomegranate
Diseases
:
Uterus: Contraction/Expulsion Disorders
Pharmacological Actions
:
Uterotonic
Additional Keywords
:
Plant Extracts
[+]
Pomegranate extract exerts a preventative effect on unilateral ureteral obstruction induced kidney damage in rats by reducing oxidative stress.
Mar 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Urol Ann. 2015 Apr-Jun;7(2):166-71. PMID:
25838069
Article Published Date
: Mar 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Kidney Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Renoprotective
Additional Keywords
:
Plant Extracts
[+]
Pomegranate extract improves colitis in IL-10 knockout mice fed a high fat high sucrose diet.
Dec 20, 2021
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2021 Dec 21:e2100730. Epub 2021 Dec 21. PMID:
34932869
Article Published Date
: Dec 20, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Colitis
,
High Fat Diet
,
High Sugar Diet
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Pomegranate extract improves several markers of NAFLD.
Dec 12, 2022
Click here to read the entire abstract
Pubmed Data
: Diabetes Metab Syndr. 2022 Dec 13 ;17(1):102693. Epub 2022 Dec 13. PMID:
36535123
Article Published Date
: Dec 12, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-6 Downregulation
[+]
Pomegranate extract is abundant in hydrolysable tannins that display multiple anti-acne capacities.
Jan 11, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2017 Jan 12 ;18(1). Epub 2017 Jan 12. PMID:
28085116
Article Published Date
: Jan 11, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Acne
Pharmacological Actions
:
Anti-Bacterial Agents
,
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Prostaglandin PGE2 downregulation
Additional Keywords
:
Plant Extracts
[+]
pomegranate extract merits further investigation as a complementary approach to alleviate obesity, reducing the low grade of chronic inflammation and metabolic stress.
Sep 08, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2022 Sep 9 ;23(18). Epub 2022 Sep 9. PMID:
36142372
Article Published Date
: Sep 08, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
High Fat Diet
,
Inflammation
,
Insulin Resistance
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
[+]
Pomegranate extract protects against alcohol and aspirin-induced gastric mucosal injury.
Jan 04, 2005
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2005 Jan 4;96(1-2):171-6. PMID:
15588667
Article Published Date
: Jan 04, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Alcohol Toxicity
,
Aspirin-Induced Toxicity
,
Gastric Ulcer
,
NSAID-induced toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Ulcer Agents
,
Antioxidants
,
Gastroprotective
Additional Keywords
:
Plant Extracts
[+]
Pomegranate extract reduced aortic sinus and coronary artery atherosclerosis in SR-BI/apoE dKO mice.
Apr 30, 2013
Click here to read the entire abstract
Pubmed Data
: Atherosclerosis. 2013 May ;228(1):80-9. Epub 2013 Mar 7. PMID:
23528829
Article Published Date
: Apr 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Atherosclerosis
,
Clogged Arteries
,
Coronary Artery Disease
[+]
Pomegranate extracts and exercise may be additively effective in improving immune function in HFD-fed rats.
Feb 27, 2016
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2016 Feb 28 ;32:20-28. Epub 2016 Feb 28. PMID:
27142733
Article Published Date
: Feb 27, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
High Fat Diet
,
Inflammation
,
Oxidative Stress
Therapeutic Actions
:
Exercise
,
Integrative Medicine
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Pomegranate extracts can accelerate the wound healing process.
Feb 28, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Vet World. 2018 Mar ;11(3):321-326. Epub 2018 Mar 17. PMID:
29657424
Article Published Date
: Feb 28, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ellagic Acid
,
Pomegranate
Diseases
:
Wound Healing
[+]
Pomegranate extracts were effective in the treatment of drug induced nephrotoxicity.
Oct 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Vet World. 2016 Nov ;9(11):1269-1274. Epub 2016 Nov 17. PMID:
27956780
Article Published Date
: Oct 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Antibiotic Toxicity
,
Chemotherapy-Induced Toxicity: Gentamicin
,
Kidney Failure: Acute
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
Additional Keywords
:
Plant Extracts
[+]
Pomegranate flower polyphenols prevents high fat diet-induced obesity in Apo E-/- mice.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Transl Res. 2017 ;9(6):3073-3083. Epub 2017 Jun 15. PMID:
28670394
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate flower
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
,
Obesity
Additional Keywords
:
Anti-Obesity Agents
,
Gene Expression Regulation
[+]
Pomegranate fruit extract and its components suppressed the formation of AGEs from bovine serum albumin and sugars.
Aug 04, 2015
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2015 Aug 5. Epub 2015 Aug 5. PMID:
26242637
Article Published Date
: Aug 04, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ellagic Acid
,
Gallic Acid
,
Pomegranate
Diseases
:
Advanced Glycation End products (AGE)
Additional Keywords
:
Plant Extracts
[+]
Pomegranate fruit extract reversed arsenic-induced hepatotoxicity and apoptosis.
Sep 05, 2016
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2016 Sep 6 ;38:25-40. Epub 2016 Aug 6. PMID:
27723467
Article Published Date
: Sep 05, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Hepatoprotective
Problem Substances
:
Arsenic
[+]
Pomegranate fruit extract rich in punicalagin reverses the proatherogenic effects of perturbed shear stress on endothelial function in rats.
Jan 15, 2007
Click here to read the entire abstract
Pubmed Data
: Cardiovasc Res. 2007 Jan 15;73(2):414-23. Epub 2006 Sep 1. PMID:
17014835
Article Published Date
: Jan 15, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Arteriosclerosis
,
Endothelial Dysfunction
[+]
Pomegranate fruit extract significantly inhibits lung tumorigenesis in A/J mice.
Mar 31, 2007
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Res. 2007 Apr 1 ;67(7):3475-82. Epub 2007 Mar 27. PMID:
17389758
Article Published Date
: Mar 31, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Benzo[a]pyrene-induced Toxicity
,
Lung Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
,
NF-kappaB Inhibitor
Additional Keywords
:
Anticarcinogenic Agents
,
Chemopreventive
,
lung cancer
,
NF-kappaB Inhibitor
,
Phytotherapy
,
Plant Extracts
,
pomegranate
Problem Substances
:
Benzo(a)pyrene
[+]
Pomegranate fruit juice suppressed androgen dependent prostate carcinogenesis.
Oct 03, 2014
Click here to read the entire abstract
Pubmed Data
: Prostate. 2014 Oct 4. Epub 2014 Oct 4. PMID:
25284475
Article Published Date
: Oct 03, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ellagic Acid
,
Pomegranate
Diseases
:
Cancer: Prostate
,
Prostate Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Bax/Bcl2 ratio: Increase
,
Caspase-3 Activation
,
Chemopreventive
[+]
Pomegranate fruits aqueous extract administration contributes to the modulation of both hyperglycemia and hyperlipidemia.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Iran J Pharm Res. 2019 ;18(1):358-368. PMID:
31089370
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Hyperglycemia
,
Hyperlipidemia
Pharmacological Actions
:
Hypoglycemic Agents
,
Hypolipidemic
Additional Keywords
:
Plant Extracts
[+]
Pomegranate glycolic extract had antimicrobial action against P. gingivalis in vivo.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: ScientificWorldJournal. 2016;2016:8626987. Epub 2016 Aug 7. PMID:
27668280
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Periodontal Diseases
,
Porphyromonas gingivalis
Pharmacological Actions
:
Antimicrobial
Additional Keywords
:
Plant Extracts
[+]
Pomegranate has a protective effect on experimental ischemia/reperfusion retinal injury in rats.
Aug 09, 2017
Click here to read the entire abstract
Pubmed Data
: Ultrastruct Pathol. 2017 Aug 10:1-12. Epub 2017 Aug 10. PMID:
28796566
Article Published Date
: Aug 09, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Ischemia
Pharmacological Actions
:
Antioxidants
,
Nrf2 activation
[+]
Pomegranate has blood sugar regulating properties.
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2011 ;39(5):1015-27. PMID:
21905289
Article Published Date
: Jan 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Blood Sugar Problems
,
Hyperglycemia
Pharmacological Actions
:
SGLT1 inducer
[+]
Pomegranate hull extract has antitumorigenic effect and could be a candidate for anticancer drugs.
Jul 05, 2016
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2016 Jul 6:1-8. Epub 2016 Jul 6. PMID:
27383944
Article Published Date
: Jul 05, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Bcl-2 protein down-regulation
,
Cyclin D1 Down-Regulation
Additional Keywords
:
Plant Extracts
[+]
Pomegranate improves depressive symptoms and bone properties in a menopausal syndrome model due to its estrogen content (estradiol, estrone and estriol).
May 01, 2004
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2004 May;92(1):93-101. PMID:
15099854
Article Published Date
: May 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Depression: Postmenopausal
,
Estrogen Deficiency
,
Menopausal Syndrome
,
Osteoporosis
Pharmacological Actions
:
Antidepressive Agents
Additional Keywords
:
Ovariectomy-Induced Changes
,
Plant Extracts
[+]
Pomegranate is promising in development a functional biomolecule in treatment and protection against diabetic complications as nephropathy.
Oct 02, 2022
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2022 Oct 3. Epub 2022 Oct 3. PMID:
36190633
Article Published Date
: Oct 02, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Pomegranate
Diseases
:
Diabetic Nephropathy
Pharmacological Actions
:
Anti-Glycation Agents
,
Anti-Inflammatory Agents
,
Antioxidants
[+]
Pomegranate juice ameliorates dopamine release and behavioral deficits.
Aug 24, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Brain Sci. 2021 Aug 25 ;11(9). Epub 2021 Aug 25. PMID:
34573149
Article Published Date
: Aug 24, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Parkinson's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Pomegranate juice and punicalagin-mediated chemoprevention of hepatocellular carcinogenesis.
Nov 01, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Cell Int. 2022 Nov 2 ;22(1):333. Epub 2022 Nov 2. PMID:
36324170
Article Published Date
: Nov 01, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
,
Punicalagin
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Apoptotic
,
Bcl-2 protein down-regulation
,
Bcl-xL down-regulation
,
Chemopreventive
,
MicroRNA modulator
,
NF-kappaB Inhibitor
[+]
Pomegranate juice can be potentially used for the treatment of inflammatory bowel disease.
Jun 27, 2016
Click here to read the entire abstract
Pubmed Data
: Mol Cell Biochem. 2016 Jun 28. Epub 2016 Jun 28. PMID:
27352379
Article Published Date
: Jun 27, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Pomegranate juice can prevent NAFLD even in the presence of the other risk factors.
Sep 21, 2016
Click here to read the entire abstract
Pubmed Data
: J Sci Food Agric. 2016 Sep 22. Epub 2016 Aug 22. PMID:
27717115
Article Published Date
: Sep 21, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Prophylactic Agents
Additional Keywords
:
Risk Reduction
[+]
Pomegranate juice concentrated powder has favourable protective effects against UVB-induced photoaging through anti-apoptotic effects.
Jul 31, 2017
Click here to read the entire abstract
Pubmed Data
: Exp Ther Med. 2017 Aug ;14(2):1023-1036. Epub 2017 Jun 16. PMID:
28810554
Article Published Date
: Jul 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Photoprotective
[+]
Pomegranate juice consumption ameliorates the carbon tetrachloride induced damages in male reproductive organs.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Toxicol Ind Health. 2016 Jan ;32(1):126-37. Epub 2013 Sep 30. PMID:
24081635
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Chemical Exposure
Pharmacological Actions
:
Antioxidants
,
Cytoprotective
[+]
Pomegranate juice could be beneficial as a dietary supplement in patients receiving chemotherapy medications.
Aug 05, 2015
Click here to read the entire abstract
Pubmed Data
: Arch Physiol Biochem. 2015 Aug 6:1-5. Epub 2015 Aug 6. PMID:
26247305
Article Published Date
: Aug 05, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
[+]
Pomegranate juice could protect against sodium fluoride induced oxidative injury.
Feb 11, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Can J Physiol Pharmacol. 2016 Feb 12:1-10. Epub 2016 Feb 12. PMID:
27124270
Article Published Date
: Feb 11, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Fluoride Toxicity
Pharmacological Actions
:
Antioxidants
,
Prophylactic Agents
Problem Substances
:
Sodium Fluoride
[+]
Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimer's disease.
Nov 30, 2006
Click here to read the entire abstract
Pubmed Data
: Neurobiol Dis. 2006 Dec ;24(3):506-15. Epub 2006 Sep 28. PMID:
17010630
Article Published Date
: Nov 30, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Pomegranate
Pharmacological Actions
:
Antioxidants
[+]
Pomegranate juice exacerbates oxidative stress and nigrostriatal degeneration in a Parkinson's disease model.
Apr 30, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neurobiol Aging. 2014 May ;35(5):1162-76. Epub 2013 Oct 21. PMID:
24315037
Article Published Date
: Apr 30, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
Pomegranate juice extract ameliorated polycystic ovary syndrome accompanying endometrial histological alterations.
May 18, 2021
Click here to read the entire abstract
Pubmed Data
: Morphologie. 2021 May 19. Epub 2021 May 19. PMID:
34023214
Article Published Date
: May 18, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Polycystic Ovary Syndrome
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Antiproliferative
[+]
Pomegranate juice has a chondroprotective effect in an animal mode of osteoarthritis of the knee joint.
Jun 05, 2009
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2009 Jun 5. PMID:
19504467
Article Published Date
: Jun 05, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Osteoarthritis
,
Osteoarthritis: Knee
[+]
Pomegranate juice has a protective effect on kidney stone formation (nephrolithiasis) in rats.
Nov 01, 2010
Click here to read the entire abstract
Pubmed Data
: Bone. 2010 Nov;47(5):926-37. Epub 2010 Aug 7. PMID:
19025399
Article Published Date
: Nov 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Kidney Stones
[+]
Pomegranate juice has protective effects of on nephrotoxicity induced by captopril and gentamicin in rats.
Oct 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Iran J Kidney Dis. 2017 Nov ;11(6):422-429. PMID:
29190602
Article Published Date
: Oct 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Chemotherapy-Induced Toxicity: Gentamicin
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Prophylactic Agents
[+]
Pomegranate juice may be effective against oxidative stress in diabetic retinas.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Ophthalmol. 2017 ;10(11):1662-1668. Epub 2017 Nov 18. PMID:
29181308
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Diabetes: Oxidative Stress
,
Diabetic Retinopathy
Pharmacological Actions
:
Antioxidants
[+]
Pomegranate juice might have a preventive effect in paracetamol-induced acute liver damage.
May 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Turk Pediatri Ars. 2016 Jun ;51(2):72-8. Epub 2016 Jun 1. PMID:
27489463
Article Published Date
: May 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Acetaminophen (Tylenol) Toxicity
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Pomegranate juice moderates anxiety- and depression-like behaviors.
Aug 16, 2021
Click here to read the entire abstract
Pubmed Data
: J Trace Elem Med Biol. 2021 Aug 17 ;68:126842. Epub 2021 Aug 17. PMID:
34418746
Article Published Date
: Aug 16, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Aluminum Toxicity
,
Anxiety
,
Depression
Pharmacological Actions
:
Anti-Anxiety Agents
,
Antidepressive Agents
Problem Substances
:
Aluminum
[+]
Pomegranate juice possesses a promising inhibitory effect on bladder cancer development.
Sep 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Heliyon. 2020 Oct ;6(10):e05192. Epub 2020 Oct 8. PMID:
33083625
Article Published Date
: Sep 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Bladder Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemopreventive
,
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Pomegranate juice protects against the effects of a high-fat diet in body weight, and cholesterol levels.
Feb 26, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2017 Feb 27. Epub 2017 Feb 27. PMID:
28243786
Article Published Date
: Feb 26, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
High Fat Diet
Pharmacological Actions
:
Anticholesteremic Agents
[+]
Pomegranate juice reduces blood pressure by inhibiting Angiotensin Converting Enzyme (ACE) activity in diabetic rats.
Dec 17, 2009
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2009 Dec 17. PMID:
20020514
Article Published Date
: Dec 17, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Diabetes: Cardiovascular Illness
,
Hypertension
Pharmacological Actions
:
Angiotensin-Converting Enzyme Inhibitors
[+]
Pomegranate juice rescues developmental, neurobehavioral and biochemical disorders in aluminum chloride-treated male mice.
Dec 31, 2020
Click here to read the entire abstract
Pubmed Data
: J Trace Elem Med Biol. 2021 Jan ;63:126655. Epub 2020 Sep 29. PMID:
33045674
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Aluminum Toxicity
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
Problem Substances
:
Aluminum Chloride
[+]
Pomegranate juice reverses AlCl 3-Induced neurotoxicity and improves learning and memory in female mice.
Jul 31, 2021
Click here to read the entire abstract
Pubmed Data
: Environ Res. 2021 Aug ;199:111270. Epub 2021 May 13. PMID:
33992638
Article Published Date
: Jul 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Aluminum Toxicity
Pharmacological Actions
:
Neuroprotective Agents
Problem Substances
:
Aluminum
[+]
Pomegranate juice shows antioxidant activity against cutaneous leishmaniasis-induced oxidative stress.
Dec 17, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Environ Res Public Health. 2017 Dec 18 ;14(12). Epub 2017 Dec 18. PMID:
29258248
Article Published Date
: Dec 17, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Leishmaniasis
Pharmacological Actions
:
Antioxidants
,
Leishmanicidal
[+]
Pomegranate juice supplementation significantly decreased the incidence of lung cancer.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2017 ;2017:6063201. Epub 2017 Nov 30. PMID:
29333211
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Lung Cancer: Prevention
,
Smoking
Pharmacological Actions
:
Chemopreventive
,
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
[+]
Pomegranate juice was found as an effective strategy against acrolein atherogenicity.
Sep 29, 2016
Click here to read the entire abstract
Pubmed Data
: Arch Toxicol. 2016 Sep 30. Epub 2016 Aug 30. PMID:
27696135
Article Published Date
: Sep 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Polyphenols
,
Pomegranate
Diseases
:
Atherosclerosis
Pharmacological Actions
:
Anti-atherogenic
,
Antioxidants
Additional Keywords
:
Microbiota
[+]
Pomegranate juice was proved to be a potential hepato-renal protective agent against liver and kidney damage induced by copper oxide nanoparticles.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Nanomedicine. 2019 ;14:8905-8922. Epub 2019 Nov 15. PMID:
31814719
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Chemically-Induced Liver Damage
,
Kidney Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Renoprotective
Problem Substances
:
Copper Oxide
[+]
Pomegranate leaf attenuates lipid absorption in the small intestine in hyperlipidemic mice.
Sep 30, 2017
Click here to read the entire abstract
Pubmed Data
: Chin J Nat Med. 2017 Oct ;15(10):732-739. PMID:
29103458
Article Published Date
: Sep 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Hyperlipidemia
Pharmacological Actions
:
Hypolipidemic
[+]
Pomegranate leaf extract attenuates lung inflammation in mice with acute lung injury.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: J Immunol Res. 2018 ;2018:6879183. Epub 2018 Feb 20. PMID:
29675437
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Pomegranate may be supportive in the preservation of bone density and the treatment of vaginal epithelial atrophy.
Mar 29, 2018
Click here to read the entire abstract
Pubmed Data
: J Obstet Gynaecol Res. 2018 Mar 30. Epub 2018 Mar 30. PMID:
29603520
Article Published Date
: Mar 29, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Osteoporosis
,
Vaginal Atrophy
Pharmacological Actions
:
Osteoprotective
[+]
Pomegranate mesocarp preparations could represent a complementary approach to conventional therapies for promoting abdominal pain relief.
Jun 16, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2020 Jun 17 ;21(12). Epub 2020 Jun 17. PMID:
32560291
Article Published Date
: Jun 16, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Colitis
Pharmacological Actions
:
Analgesics
[+]
Pomegranate peel anthocyanins prevent diet-induced obesity and insulin resistance.
Jan 17, 2022
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2022 Jan 18. Epub 2022 Jan 18. PMID:
35039918
Article Published Date
: Jan 17, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Insulin Resistance
,
Obesity
Pharmacological Actions
:
Gastrointestinal Agents
Additional Keywords
:
Anthocyanins
[+]
Pomegranate peel attenuates dextran sulfate sodium-induced lipid peroxidation.
Jan 07, 2021
Click here to read the entire abstract
Pubmed Data
: J Sci Food Agric. 2021 Jan 8. Epub 2021 Jan 8. PMID:
33417238
Article Published Date
: Jan 07, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Lipid Peroxidation
Pharmacological Actions
:
Antioxidants
,
Gastroprotective
[+]
Pomegranate peel decreased the hematotoxic and genotoxic effects induced by Barium chloride due to its powerful antioxidant capacity.
Mar 11, 2016
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2016 Mar 12:1-11. Epub 2016 Mar 12. PMID:
26971618
Article Published Date
: Mar 11, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Barium Toxicity
Pharmacological Actions
:
Antioxidants
Problem Substances
:
Barium
[+]
Pomegranate peel extract alters the microbiome in mice and dysbiosis caused by citrobacter todentium infection.
May 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Curr Dev Nutr. 2019 Jun ;3(Suppl 1). Epub 2019 Jun 13. PMID:
31223720
Article Published Date
: May 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Citrobacter Infection
,
Dysbiosis
Pharmacological Actions
:
Gastrointestinal Agents
[+]
Pomegranate peel extract ameliorates the severity of experimental autoimmune encephalomyelitis.
Nov 08, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Gut Microbes. 2020 Nov 9 ;12(1):1857515. PMID:
33382357
Article Published Date
: Nov 08, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Encephalomyelitis
Pharmacological Actions
:
Gastrointestinal Agents
[+]
Pomegranate peel extract attenuates isoprenaline-induced Takotsubo-like myocardial injury.
Jun 08, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Pharmaceutics. 2023 Jun 9 ;15(6). Epub 2023 Jun 9. PMID:
37376144
Article Published Date
: Jun 08, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Heart Failure
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
[+]
Pomegranate peel extract attenuates small intestine lipid peroxidation and strengthens the first line of small intestine antioxidant defences.
Nov 12, 2015
Click here to read the entire abstract
Pubmed Data
: J Sci Food Agric. 2015 Nov 13. Epub 2015 Nov 13. PMID:
26564426
Article Published Date
: Nov 12, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Lipid Peroxidation
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
Additional Keywords
:
Plant Extracts
[+]
Pomegranate peel extract can protect against age-related hearing loss.
Jul 24, 2017
Click here to read the entire abstract
Pubmed Data
: Neurobiol Aging. 2017 Jul 25 ;59:30-40. Epub 2017 Jul 25. PMID:
28837860
Article Published Date
: Jul 24, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Hearing Loss
Pharmacological Actions
:
Antioxidants
[+]
Pomegranate peel extract consumption conferred protection against hypertension in the spontaneously hypertensive rat (SHR) model.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Toxicol Environ Health A. 2016 ;79(21):998-1007. Epub 2016 Aug 15. PMID:
27710705
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Coronary Artery Disease
,
Hypertension
Pharmacological Actions
:
Angiotensin-Converting Enzyme Inhibitors
,
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Pomegranate peel extract decreases plaque necrosis and advanced atherosclerosis progression.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Front Pharmacol. 2022 ;13:888300. Epub 2022 Jun 1. PMID:
35721222
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Atherosclerosis
Pharmacological Actions
:
Anticholesteremic Agents
,
Hypoglycemic Agents
,
Hypolipidemic
[+]
Pomegranate peel extract has a protective effect on concanavalin A-induced autoimmune hepatitis.
Feb 07, 2018
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2018 Feb 8 ;100:213-220. Epub 2018 Feb 8. PMID:
29428670
Article Published Date
: Feb 07, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Hepatitis: Autoimmune
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interferon Gamma Reducer
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Pomegranate peel extract has revealed desirable changes on the effective parameters in infertility.
Jul 21, 2017
Click here to read the entire abstract
Pubmed Data
: J Complement Integr Med. 2017 Jul 22. Epub 2017 Jul 22. PMID:
28734114
Article Published Date
: Jul 21, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Infertility: Male
Additional Keywords
:
Plant Extracts
[+]
Pomegranate peel extract might be considered as a potential lead material in the treatment of NAFLD and obesity.
Feb 29, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Prev Nutr Food Sci. 2016 Mar ;21(1):14-23. Epub 2016 Mar 31. PMID:
27069901
Article Published Date
: Feb 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Pomegranate peel extract prevents liver fibrosis in biliary-obstructed rats.
Sep 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Pharm Pharmacol. 2007 Sep;59(9):1287-95. PMID:
17939210
Article Published Date
: Sep 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Biliary Obstruction
,
Fibrosis: Liver
,
Liver Fibrosis
[+]
Pomegranate peel extract protects against carbon tetrachloride-induced nephrotoxicity.
Aug 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Rep. 2020 Sep ;13(3):13. Epub 2020 Jun 26. PMID:
32765852
Article Published Date
: Aug 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Kidney Damage: Chemically-Induced
Pharmacological Actions
:
Antioxidants
,
Renoprotective
[+]
Pomegranate peel extract protects against ionizing radiation-induced enteritis and leukocyte damage in rats.
Jul 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Radiat Res (Tokyo). 2009 Jul;50(4):345-53. Epub 2009 May 29. PMID:
19478462
Article Published Date
: Jul 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Radiation Induced Illness
Pharmacological Actions
:
Anti-Apoptotic
,
Radioprotective
Additional Keywords
:
Plant Extracts
[+]
Pomegranate peel extract protects against the development of diabetic cardiomyopathy.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2023 ;14:1166653. Epub 2023 Mar 28. PMID:
37056985
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Cardiomyopathy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Interleukin-1 beta downregulation
[+]
Pomegranate peel extract reduced colonic damage and bacterial translocation in a mouse model of infectious colitis induced by Citrobacter rodentium.
Nov 15, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Res. 2019 Nov 16 ;73:27-37. Epub 2019 Nov 16. PMID:
31841745
Article Published Date
: Nov 15, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Citrobacter Infection
,
Colitis
Pharmacological Actions
:
Gastroprotective
[+]
Pomegranate peel had protective effects against barium induced renal oxidative damage.
Feb 01, 2016
Click here to read the entire abstract
Pubmed Data
: Arch Physiol Biochem. 2016 Feb 2:1-40. Epub 2016 Feb 2. PMID:
26835741
Article Published Date
: Feb 01, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Barium Toxicity
Pharmacological Actions
:
Antioxidants
,
Renoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Barium
[+]
Pomegranate peel has anti-inflammatory, antiapoptotic, free-radical-scavenging, and powerful antioxidant activity that protects against acrylamide toxicity.
Jan 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Life (Basel). 2022 Jan 31 ;12(2). Epub 2022 Jan 31. PMID:
35207511
Article Published Date
: Jan 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ellagic Acid
,
Pomegranate Peel
Diseases
:
Acrylamide-induced toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Nrf2 activation
Problem Substances
:
Acrylamide
[+]
Pomegranate peel polyphenols reduce chronic low-grade inflammatory responses in rats fed a high-fat diet.
Nov 12, 2019
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2019 Nov 13. Epub 2019 Nov 13. PMID:
31720661
Article Published Date
: Nov 12, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
,
Pomegranate Polyphenols
,
Punicalagin
,
Urolithin A
Diseases
:
High Fat Diet
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
[+]
Pomegranate peel polysaccharides could be used as an alternative means in lessening chemotherapy-induced immunosuppression.
Jun 19, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2019 Jun 20. Epub 2019 Jun 20. PMID:
31229542
Article Published Date
: Jun 19, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Immunostimulatory
Additional Keywords
:
Polysaccharides
[+]
Pomegranate peel, flower and seed oil have anti-inflammatory properties. Pomegranate seed oil also improved insulin sensitivity.
Jan 27, 2016
Click here to read the entire abstract
Pubmed Data
: Arch Physiol Biochem. 2016 Jan 28:1-40. Epub 2016 Jan 28. PMID:
26822470
Article Published Date
: Jan 27, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate flower
,
Pomegranate Peel
,
Pomegranate Seed
Diseases
:
Inflammation
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Insulin Sensitizers
[+]
Pomegranate polyphenol punicalagin improves learning memory deficits, redox homeostasis, and neuroinflammation.
Apr 23, 2023
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2023 Apr 24. Epub 2023 Apr 24. PMID:
37092799
Article Published Date
: Apr 23, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Polyphenols
Diseases
:
Aging: Brain
,
Brain Inflammation
,
Memory Disorders
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Pomegranate polyphenols and extract inhibit nuclear factor of activated T-cell activity and microglial activation in vitro and in a transgenic mouse model of Alzheimer disease.
Apr 30, 2013
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2013 May ;143(5):597-605. Epub 2013 Mar 6. PMID:
23468550
Article Published Date
: Apr 30, 2013
Study Type
: In Vitro Study, Transgenic Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Brain: Microglial Activation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Pomegranate polyphenols and resveratrol protect the neonatal brain against hypoxic-ischemic injury.
Dec 31, 2006
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Dev Neurosci. 2007 ;29(4-5):363-72. PMID:
17762204
Article Published Date
: Dec 31, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
,
Resveratrol
Diseases
:
Brain Hypoxia
,
Brain Ischemia
Pharmacological Actions
:
Antioxidants
,
Apoptotic
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Pomegranate protects liver against cecal ligation and puncture-induced oxidative stress and inflammation in rats.
Mar 14, 2016
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol Pharmacol. 2016 Mar 15 ;43:182-192. Epub 2016 Mar 15. PMID:
27011232
Article Published Date
: Mar 14, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Lipid Peroxidation
,
Liver Damage
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
NF-kappaB Inhibitor
[+]
Pomegranate red peel extract was found to have antioxidant activity that could significantly enhance the serum biochemical parameters.
May 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Parasit Dis. 2019 Jun ;43(2):215-228. Epub 2019 Jan 14. PMID:
31263326
Article Published Date
: May 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
Pomegranate seed and peel methanolic extracts could protect against methotrexate induced oxidative stress and lipid profile changes in rats.
May 31, 2017
Click here to read the entire abstract
Pubmed Data
: Adv Pharm Bull. 2017 Jun ;7(2):269-274. Epub 2017 Jun 30. PMID:
28761829
Article Published Date
: May 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
,
Pomegranate Seed
Diseases
:
Drug Toxicity: Methotrexate
,
Oxidative Stress
Pharmacological Actions
:
Anticholesteremic Agents
,
Antioxidants
,
Hypolipidemic
Additional Keywords
:
Plant Extracts
[+]
Pomegranate seed extract attenuates chemotherapy-induced acute nephrotoxicity and hepatotoxicity.
May 06, 2011
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2011 May 6. Epub 2011 May 6. PMID:
21548807
Article Published Date
: May 06, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Seed
Diseases
:
Chemotherapy-Induced Liver Toxicity
,
Chemotherapy-Induced Toxicity
Pharmacological Actions
:
Antioxidants
,
Glutathione S-transferase Inhibitor
,
Hepatoprotective
,
Renoprotective
[+]
Pomegranate seed oil and bitter melon extract supplemented in diet influence the lipid profile and intensity of peroxidation in livers of SPRD rats exposed to a chemical carcinogen.
Oct 08, 2020
Click here to read the entire abstract
Pubmed Data
: Prostaglandins Other Lipid Mediat. 2020 Oct 9 ;152:106495. Epub 2020 Oct 9. PMID:
33045366
Article Published Date
: Oct 08, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Melon
,
Pomegranate
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
[+]
Pomegranate seed oil decreased obesity-mediated insulin resistance and the progression of hepatic fibrosis.
Jul 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2020 Jul 31 ;21(15). Epub 2020 Jul 31. PMID:
32751794
Article Published Date
: Jul 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Seed
Diseases
:
Hepatic Steatosis
,
Liver Fibrosis
,
Obesity
Pharmacological Actions
:
Anti-Fibrotic
,
Antioxidants
,
Hepatoprotective
[+]
Pomegranate seed oil demonstrated an important therapeutic effect in the treatment of ovarian ischemia and reperfusion injury.
Nov 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Iran J Basic Med Sci. 2018 Dec ;21(12):1262-1268. PMID:
30627370
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Seed
Diseases
:
Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Pomegranate seed oil extract has therapeutic effects on osteoporosis.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: J Nutr Health Aging. 2017 ;21(10):1299-1306. PMID:
29188893
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Seed
Diseases
:
Osteoporosis
Pharmacological Actions
:
Osteoprotective
Additional Keywords
:
Plant Extracts
,
Plant Oils
[+]
Pomegranate seed oil fed to mice enhances B-cell function as measured by immunoglobulins G and M.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2006 Jan;22(1):54-9. Epub 2005 Oct 12. PMID:
16226015
Article Published Date
: Jan 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
,
Punicic acid
Diseases
:
Immune Disorders: Low Immune Function
Pharmacological Actions
:
Immunomodulatory
[+]
Pomegranate seed oil has a protective effect against diabetes complications in rats.
Jul 24, 2016
Click here to read the entire abstract
Pubmed Data
: Ren Fail. 2016 Jul 25:1-11. Epub 2016 Jul 25. PMID:
27453190
Article Published Date
: Jul 24, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Seed
Diseases
:
Diabetic Complications
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hypoglycemic Agents
,
Hypolipidemic
,
Malondialdehyde Down-regulation
[+]
Pomegranate seed oil has a protective effect against diabetes-induced alterations in oxidant/antioxidant balance in tissues.
Jun 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Avicenna J Phytomed. 2017 Jul-Aug;7(4):317-333. PMID:
28884082
Article Published Date
: Jun 30, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Pomegranate Seed
Diseases
:
Diabetic Complications
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Oils
[+]
Pomegranate seed oil has a protective effect against pesticide-induced nephrotoxicity in rats.
Jun 01, 2010
Click here to read the entire abstract
Pubmed Data
: Ren Fail. 2010 Jun;32(5):612-7. PMID:
20486845
Article Published Date
: Jun 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Kidney Damage
,
Pesticide Toxicity
Pharmacological Actions
:
Renoprotective
[+]
Pomegranate seed oil is an effective agent for the prevention of cisplatin-induced renal dysfunction and oxidative damage in rat.
Aug 18, 2015
Click here to read the entire abstract
Pubmed Data
: Ren Fail. 2015 Aug 19:1-6. Epub 2015 Aug 19. PMID:
26288026
Article Published Date
: Aug 18, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Seed
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Renoprotective
Additional Keywords
:
Plant Oils
[+]
Pomegranate seed oil rich in punicic acid has a positive effect on lipid metabolism (particularly triglycerol metabolism) in obese, hyperlipidemic rats.
Nov 09, 2004
Click here to read the entire abstract
Pubmed Data
: Lipids Health Dis. 2004 Nov 9;3:24. PMID:
15533261
Article Published Date
: Nov 09, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
,
Punicic acid
Diseases
:
Hyperlipidemia
,
Triglycerides: Elevated
[+]
Pomegranate seed oil suppresses chemically induced colon cancer in rats.
Jun 01, 2004
Click here to read the entire abstract
Pubmed Data
: Cancer Sci. 2004 Jun;95(6):481-6. PMID:
15182427
Article Published Date
: Jun 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Colon Cancer
[+]
Pomegranate was shown to have a vasospasm attenuating effect on the basilar artery in the rabbit SAH model.
Aug 09, 2016
Click here to read the entire abstract
Pubmed Data
: J Neurol Surg A Cent Eur Neurosurg. 2016 Aug 10. Epub 2016 Aug 10. PMID:
27509316
Article Published Date
: Aug 09, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Subarachnoid hemorrhage
[+]
Pomegranate, apple and prickly pear vinegars may prevent HFD-induced obesity and obesity-related cardiac complications.
Sep 04, 2016
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2016 Sep 5:1-10. Epub 2016 Sep 5. PMID:
27595296
Article Published Date
: Sep 04, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Apple Cider Vinegar
,
Pomegranate
,
Prickly Pear Cactus
,
Vinegar
Diseases
:
High Fat Diet
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Anti-Obesity Agents
[+]
Pomegranate, cork oak and broad bean extracts in vivo antifungal activity.
Nov 13, 2016
Click here to read the entire abstract
Pubmed Data
: J Mycol Med. 2016 Nov 14. Epub 2016 Nov 14. PMID:
27856170
Article Published Date
: Nov 13, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Beans: All
,
Oak
,
Pomegranate
Diseases
:
Candida Albicans
,
Candidiasis
,
Fungal Infection
Pharmacological Actions
:
Antifungal Agents
Additional Keywords
:
Plant Extracts
[+]
Pomegranate-derived anthocyanin regulates MORs-cAMP/CREB-BDNF pathways in opioid-dependent models and improves cognitive impairments.
May 15, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ayurveda Integr Med. 2020 May 16. Epub 2020 May 16. PMID:
32430240
Article Published Date
: May 15, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Pomegranate
Diseases
:
Cognitive Decline/Dysfunction
,
Memory Disorders
Pharmacological Actions
:
Brain-derived neurotrophic factor modulator
,
Neuroprotective Agents
[+]
Promoting effect of pomegranate peel extract on second-degree burn wound-healing through VEGF-A and TGF-β1 regulation.
Jun 20, 2021
Click here to read the entire abstract
Pubmed Data
: Burns. 2021 Jun 21. Epub 2021 Jun 21. PMID:
34716043
Article Published Date
: Jun 20, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Burns
Pharmacological Actions
:
Transforming growth factor beta (TGF-β) upregulation
,
Vascular Endothelial Growth Factor A Enhancer
[+]
Protective action of pomegranate peel polyphenols in type 2 diabetic rats.
Nov 14, 2021
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2021 Nov 15 ;12(22):11408-11419. Epub 2021 Nov 15. PMID:
34673854
Article Published Date
: Nov 14, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Antioxidants
,
Nrf2 activation
[+]
Protective effect of pomegranate extract against diabetic changes in adult male rat liver.
Sep 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Microsc Ultrastruct. 2019 Oct-Dec;7(4):165-170. Epub 2019 Nov 18. PMID:
31803570
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Diabetic Complications
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Hypoglycemic Agents
[+]
Punica granatum (pomegranate) ameliorates dextran sulfate sodium induced ulcerative colitis.
Apr 15, 2009
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2009 Apr 15. PMID:
19367659
Article Published Date
: Apr 15, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Ellagic Acid
,
Pomegranate
Diseases
:
Colitis: Ulcerative
,
Ulcerative Colitis
[+]
Punica granatum and amygdalin extracts plus cobalamin combined with albendazole reduce larval burden and myositis in experimental trichinosis.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Rev Bras Parasitol Vet. 2021 ;30(4):e012021. Epub 2021 Nov 1. PMID:
34730610
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Amygdalin
,
Pomegranate
,
Vitamin B-12
Diseases
:
Trichinosis
Additional Keywords
:
Natural Substance/Drug Synergy
,
Plant Extracts
[+]
Punica granatum extract shows cardioprotective effects measured by oxidative stress markers and biomarkers of heart failure.
May 24, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2023 May 25 ;12(6). Epub 2023 May 25. PMID:
37371882
Article Published Date
: May 24, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Heart Failure
,
Metabolic Syndrome X
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
[+]
Punica granatum improves renal function in gentamicin-induced nephropathy.
Mar 15, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ayurveda Integr Med. 2018 Mar 16. Epub 2018 Mar 16. PMID:
29555255
Article Published Date
: Mar 15, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Chemotherapy-Induced Toxicity: Gentamicin
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
[+]
Punica granatum L. flower is able to lower glucose levels in T2DM rats by improving the insulin resistance.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Endocrinol (Lausanne). 2018 ;9:586. Epub 2018 Oct 15. PMID:
30374328
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Hypoglycemic Agents
[+]
Punica granatum L.-derived omega-5 nanoemulsion improves hepatic steatosis in a high fat diet.
Jan 16, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2020 09 17 ;10(1):15229. Epub 2020 Sep 17. PMID:
32943651
Article Published Date
: Jan 16, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Hepatic Steatosis
,
High Fat Diet
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Phytotherapy
[+]
Punica granatum peel extract pre-treatment alleviates fenpropathrin-induced testicular injury.
Jun 02, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxics. 2023 Jun 3 ;11(6). Epub 2023 Jun 3. PMID:
37368604
Article Published Date
: Jun 02, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Testicular Injury: Chemical/Metal Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Punica granatum peel supplementation attenuates cognitive deficits and brain injury.
Dec 31, 2022
Click here to read the entire abstract
Pubmed Data
: Food Sci Nutr. 2023 Jan ;11(1):168-180. Epub 2022 Sep 12. PMID:
36655111
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Neurodegenerative Diseases
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Neuroprotective Agents
,
Nrf2 activation
[+]
Punica granatum pericarp extract suppressed tumor proliferation and angiogenesis in a model of melanoma.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Iran J Pharm Res. 2019 ;18(1):348-357. PMID:
31089369
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Melanoma
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Antiproliferative
[+]
Punica granatum protects against oxidative stress in PC12 cells and oxidative stress-induced Alzheimer's symptoms in mice.
Jun 30, 2011
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2011 Jul-Aug;14(7-8):695-701. Epub 2011 Jun 1. PMID:
21631359
Article Published Date
: Jun 30, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Brain: Oxidative Stress
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Punicalagin and ellagic acid demonstrate antimutagenic activity and inhibition of benzo[a]pyrene induced DNA adducts.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2014 ;2014:467465. Epub 2014 May 14. PMID:
24949451
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ellagic Acid
,
Pomegranate
,
Punicalagin
,
Tannic Acid
Diseases
:
Benzo[a]pyrene-induced Toxicity
,
DNA damage
Pharmacological Actions
:
Antimutagenic Agents
,
Antioxidants
Additional Keywords
:
Plant Extracts
Problem Substances
:
Benzo(a)pyrene
[+]
Punicalagin has a beneficial effect against S. typhimurium infection in mice.
Jun 17, 2015
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2015 Jun 18. Epub 2015 Jun 18. PMID:
26084785
Article Published Date
: Jun 17, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
,
Punicalagin
Diseases
:
Salmonella Infections
Pharmacological Actions
:
Anti-Infective Agents
,
Interferon Gamma Reducer
,
Interleukin-10 downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Red clover and pomegranate powder synergically and potently relieve climacterium symptoms, especially obesity and osteoporosis in menopausal females.
Mar 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2015 Apr ;7(4):2622-47. Epub 2015 Apr 9. PMID:
25912038
Article Published Date
: Mar 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
,
Red Clover
Diseases
:
Menopausal Syndrome
,
Obesity
Additional Keywords
:
Anti-Obesity Agents
,
Natural Substance Synergy
[+]
Supplementation with a punicalagin-rich pomegranate extract may protect skeletal muscle against an acute inflammation.
Nov 01, 2016
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2016 Nov 2. Epub 2016 Aug 2. PMID:
27804206
Article Published Date
: Nov 01, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
,
Punicalagin
,
Urolithin A
Diseases
:
Cachexia
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
The antiarthritic potential of a butanol fraction of Punica granatum Linn. rind extract may be due to the presence of active phytoconstituents.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: J Environ Pathol Toxicol Oncol. 2018 ;37(1):53-62. PMID:
29773000
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
The combination of pomegranate juice and tolbutamide exhibited profound protection compared to tolbutamide alone against diabetic complications.
Nov 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Integr Med Res. 2017 Dec ;6(4):354-360. Epub 2017 Aug 1. PMID:
29296562
Article Published Date
: Nov 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Diabetic Complications
Pharmacological Actions
:
Antinoceceptive
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
The combined effect of pomegranate extract and tangeretin on the DMBA-induced breast cancer model.
Dec 12, 2020
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2020 Dec 13:108566. Epub 2020 Dec 13. PMID:
33326843
Article Published Date
: Dec 12, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
,
Tangeretin
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
,
Cyclin D1 Down-Regulation
,
Tumor Suppressor Protein p53 Upregulation
[+]
The consumption of pomegranate extract amelior
