Prunella vulgaris

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81 Diseases Researched for Prunella vulgaris
NameACCKFocus
Breast Cancer823Locked
Inflammation815Locked
Escherichia coli Infections110Locked
Infection: Antibiotic Resistant110Locked
Thyroiditis: Subacute110Locked
Urinary Tract Infections110Locked
Lung Cancer57Locked
Thyroid Cancer57Locked
Allergies15Locked
Diabetic Nephropathy15Locked
Ebola Virus Infections15Locked
Thyroiditis: Autoimmune35Locked
Atherosclerosis34Locked
Diabetes Mellitus: Type 124Locked
Diabetes Mellitus: Type 224Locked
HIV Infections44Locked
Lipopolysaccharide-Induced Toxicity24Locked
Liver Cancer44Locked
Autoimmune Diseases23Locked
Breast Cancer: Metastatic13Locked
Cancers: All33Locked
Colon Cancer33Locked
Diabetic Complications23Locked
Hashimoto's thyroiditis33Locked
Mastitis13Locked
Acetaminophen (Tylenol) Toxicity 12Locked
Acute T cell Leukemias12Locked
Alcohol Toxicity 12Locked
Alcoholic Liver Disease12Locked
Alzheimer's Disease12Locked
Blue Light Toxicity12Locked
Bone Diseases12Locked
Carcinoma: Non-Small-Cell Lung12Locked
Chemically-Induced Liver Damage12Locked
Colitis12Locked
Colorectal Cancer12Locked
Dementia12Locked
Dysbiosis12Locked
Endotoxemia12Locked
Fluoride Toxicity 12Locked
Genital Herpes12Locked
Graves Disease12Locked
HSV-112Locked
HSV-212Locked
Herpes Labialis12Locked
Hyperglycemia12Locked
Hyperlipidemia12Locked
Hypertension12Locked
Liver Damage: Drug-Induced12Locked
Liver Fibrosis12Locked
Macular Degeneration12Locked
Myocardial Infarction12Locked
Oral Cancer12Locked
Oxidative Stress12Locked
Schizophrenia12Locked
Ulcerative Colitis12Locked
Wound Healing12Locked
Aging11Locked
Breast Cancer: estrogen receptor alpha-positive11Locked
Cancer Metastasis11Locked
Cardiovascular Diseases11Locked
Cerebral Ischemia11Locked
Cervical Cancer11Locked
Coronavirus Infection11Locked
Endometriosis11Locked
Equine infectious anemia11Locked
Hepatitis11Locked
Hepatitis: Lectin-Induced (concanavalin)11Locked
Herpes Simplex Virus Type 111Locked
Herpes Simplex Virus Type 211Locked
Insomnia11Locked
Lentivirus Infection 11Locked
Myoma11Locked
Myopia11Locked
Osteoporosis11Locked
Prostate Cancer11Locked
Rheumatoid Arthritis11Locked
Stomach Cancer11Locked
Thyroid Diseases11Locked
Thyroid Nodule11Locked
Ultraviolet Radiation Induced Damage11Locked
67 Pharmacological Actions Researched for Prunella vulgaris
NameACCKFocus
Anti-Inflammatory Agents2238Locked
Antioxidants1221Locked
Antiproliferative 1420Locked
Apoptotic1218Locked
NF-kappaB Inhibitor815Locked
Chemotherapeutic212Locked
Immunomodulatory912Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor912Locked
Antimicrobial211Locked
Chemoprotective Agents110Locked
Interleukin-1 beta downregulation510Locked
Interleukin-6 Downregulation610Locked
Anti-metastatic79Locked
Antiviral Agents56Locked
Cell cycle arrest46Locked
Hypoglycemic Agents36Locked
Angiogenesis Inhibitors35Locked
Anti-Allergic Agents15Locked
Anti-Fibrotic15Locked
Anti-Retroviral Agents15Locked
Chemopreventive35Locked
Neuroprotective Agents35Locked
Renoprotective15Locked
Bcl-2 protein down-regulation34Locked
Malondialdehyde Down-regulation24Locked
Superoxide Dismutase Up-regulation24Locked
Autophagy Up-regulation23Locked
Cardioprotective23Locked
Heme oxygenase-1 up-regulation23Locked
Hepatoprotective23Locked
Hypolipidemic23Locked
MicroRNA modulator23Locked
Osteoprotective 23Locked
Photoprotective23Locked
Acetylcholinesterase Inhibitor12Locked
Anti-Apoptotic22Locked
Anticarcinogenic Agents12Locked
Antinoceceptive 12Locked
Chemosensitizer12Locked
Gastrointestinal Agents12Locked
Gastroprotective12Locked
Immunomodulatory: Th17 downregulation12Locked
Interleukin-18 down-regulation12Locked
Interleukin-4 downregulation12Locked
Interleukin-8 downregulation12Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor22Locked
Neurogenesis12Locked
Nrf2 activation12Locked
Pancreato Protective Agents12Locked
Vascular Endothelial Growth Factor A Inhibitor12Locked
Anti-Bacterial Agents11Locked
Anti-HIV Agents11Locked
Anticholesteremic Agents11Locked
Antihypertensive Agents11Locked
Antineoplastic Agents11Locked
Cyclin D1 Down-Regulation11Locked
Cyclooxygenase 2 Inhibitors11Locked
Enzyme Inhibitors: Pancreatic Lipase11Locked
Estrogen Receptor Modulators11Locked
Immunosuppressive Agents11Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor11Locked
NF-E2-Related Factor-2 (Nrf2) Modulator11Locked
Prostaglandin PGE2 downregulation11Locked
Reverse Transcriptase Inhibitors11Locked
Survivin Down-Regulation11Locked
Tumor Suppressor Protein p53 Upregulation11Locked
Vascular Endothelial Growth Factor Inhibitors11Locked

View the Evidence:
84 Abstracts with Prunella vulgaris Research

[+]

Antimicrobial activity of Prunella Vulgaris extracts against multi-drug resistant Escherichia Coli from patients of urinary tract infection.Apr 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pak J Med Sci. 2018 May-Jun;34(3):616-620. PMID: 30034426
Article Published Date : Apr 30, 2018
Study Type : Human In Vitro, Human Study
Additional Links
Substances : Prunella vulgaris
Diseases : Escherichia coli Infections, Infection: Antibiotic Resistant, Urinary Tract Infections
Pharmacological Actions : Antimicrobial
Additional Keywords : Natural Substance/Drug Synergy
[+]

Initial treatment combined with Prunella vulgaris reduced prednisolone consumption for patients with subacute thyroiditis.Jan 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Transl Med. 2019 Feb ;7(3):45. PMID: 30906749
Article Published Date : Jan 31, 2019
Study Type : Human Study
Additional Links
Substances : Prunella vulgaris
Diseases : Thyroiditis: Subacute
Additional Keywords : Medication Reduction
[+]

Prunella vulgaris may be a potential adjuvant medicine for breast cancer treatment.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:806. Epub 2018 Aug 3. PMID: 30123125
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Prunella vulgaris
Diseases : Breast Cancer
Pharmacological Actions : Chemoprotective Agents, Chemotherapeutic
Additional Keywords : Natural Substance/Drug Synergy
[+]

Prunella vulgaris attenuates diabetic renal injury.Mar 29, 2017

Pubmed Data : Am J Chin Med. 2017 Mar 30:1-21. Epub 2017 Mar 30. PMID: 28359196
Article Published Date : Mar 29, 2017
Study Type : Human In Vitro
Additional Links
Substances : Prunella vulgaris
Diseases : Diabetic Nephropathy
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor, Renoprotective
[+]

Prunella vulgaris has potent anti-Ebola virus activity and may be developed as a novel antiviral approach against EBOV infection.Feb 29, 2016

Pubmed Data : Antiviral Res. 2016 Mar ;127:20-31. Epub 2016 Jan 9. PMID: 26778707
Article Published Date : Feb 29, 2016
Study Type : Human In Vitro
Additional Links
Substances : Prunella vulgaris
Diseases : Ebola Virus Infections
Pharmacological Actions : Anti-Retroviral Agents
Additional Keywords : Natural Substance/Drug Synergy
[+]

These results suggest that two compounds largely contribute to the anti-allergic inflammatory effect of P. vulgaris.Dec 31, 2015

Pubmed Data : Nat Prod Commun. 2016 Jan ;11(1):31-2. PMID: 26996013
Article Published Date : Dec 31, 2015
Study Type : Human In Vitro
Additional Links
Substances : Prunella vulgaris
Diseases : Allergies, Inflammation
Pharmacological Actions : Anti-Allergic Agents, Anti-Inflammatory Agents
[+]

A case report of Korean medicine therapy as a substitute for chemotherapy for metastatic breast cancer. Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Case Rep Oncol. 2015 Jan-Apr;8(1):64-71. Epub 2015 Feb 10. PMID: 25848354
Article Published Date : Dec 31, 2014
Study Type : Human: Case Report
Additional Links
Substances : Cordyceps sinensis, Ginseng, Prunella vulgaris, Trichosanthes Kirilowii
Diseases : Breast Cancer, Breast Cancer: Metastatic
Additional Keywords : Korean Medicine Therapy, Significant Treatment Outcome
[+]

An in vivo and in vitro assessment of the anti-breast cancer activity of crude extract and fractions from Prunella vulgaris.Oct 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Heliyon. 2022 Nov ;8(11):e11183. Epub 2022 Oct 19. PMID: 36345524
Article Published Date : Oct 31, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

P vulgaris extract can maintain the integrity of mammary connective tissue and reduce its inflammatory response to prevent acute mastitis.Jun 27, 2024

Pubmed Data : J Ethnopharmacol. 2024 Jun 28 ;328:117998. Epub 2024 Mar 12. PMID: 38484956
Article Published Date : Jun 27, 2024
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids, Prunella vulgaris
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Mastitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

An aqueous extract of Prunella vulgaris L. ameliorates cadmium-induced bone loss.Sep 30, 2023

Pubmed Data : Food Chem Toxicol. 2023 Oct ;180:114005. Epub 2023 Aug 26. PMID: 37640280
Article Published Date : Sep 30, 2023
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
Problem Substances : Cadmium
[+]

An aqueous extract of Prunella vulgaris L. inhibits the growth of papillary thyroid carcinoma by inducing autophagy.Jan 12, 2021

Pubmed Data : Phytother Res. 2021 Jan 13. Epub 2021 Jan 13. PMID: 33440461
Article Published Date : Jan 12, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Thyroid Cancer
Pharmacological Actions : Antiproliferative , Autophagy Up-regulation
[+]

An extract of P. vulgaris alleviated carbon tetrachloride-induced hepatic in vivo. Oct 12, 2015

Pubmed Data : Planta Med. 2015 Oct 13. Epub 2015 Oct 13. PMID: 26460672
Article Published Date : Oct 12, 2015
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Chemically-Induced Liver Damage, Liver Fibrosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-4 downregulation, Interleukin-8 downregulation, MicroRNA modulator, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

An extract of Prunella vulgaris could be a potential therapeutic agent to ameliorate type 1 diabetes and related complications.Nov 30, 2016

Pubmed Data : Biomed Pharmacother. 2016 Dec ;84:1008-1018. Epub 2016 Oct 18. PMID: 27768926
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Caffeic Acid, Prunella vulgaris
Diseases : Diabetes Mellitus: Type 1, Diabetic Complications
Pharmacological Actions : Antinoceceptive , Hypoglycemic Agents
Additional Keywords : Plant Extracts
[+]

Cancer chemoprevention with PV-1, a novel Prunella vulgaris-containing herbal mixture that remodels the tumor immune microenvironment.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2023 ;14:1196434. Epub 2023 Nov 24. PMID: 38077406
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Lung Cancer, Oral Cancer
Pharmacological Actions : Chemotherapeutic, Immunomodulatory
Additional Keywords : Tumor Microenvironment
[+]

In vivo hepatoprotective potential of extracts obtained from floral spikes of Prunella vulgaris LMar 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ayurveda Integr Med. 2020 Mar 31. Epub 2020 Mar 31. PMID: 32241633
Article Published Date : Mar 30, 2020
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Acetaminophen (Tylenol) Toxicity , Liver Damage: Drug-Induced
Pharmacological Actions : Hepatoprotective
Problem Substances : Acetaminophen, Paracetamol
[+]

Mechanism of Prunella vulgaris L. and luteolin in restoring Tfh/Tfr balance and alleviating oxidative stress in Graves' disease.Aug 31, 2024

Pubmed Data : Phytomedicine. 2024 Sep ;132:155818. Epub 2024 Jun 11. PMID: 38879922
Article Published Date : Aug 31, 2024
Study Type : Animal Study
Additional Links
Substances : Luteolin, Prunella vulgaris
Diseases : Graves Disease, Oxidative Stress
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
Additional Keywords : Plant Extracts
[+]

Monofloral honey from Prunella vulgaris protected against dextran sulfate sodium-induced ulcerative colitis.Jul 16, 2019

Pubmed Data : Food Funct. 2019 Jul 17 ;10(7):3828-3838. PMID: 31187840
Article Published Date : Jul 16, 2019
Study Type : Animal Study
Additional Links
Substances : Honey, Prunella vulgaris
Diseases : Ulcerative Colitis
Pharmacological Actions : Gastroprotective
[+]

Phenolic acids from Prunella vulgaris alleviate cardiac remodeling following myocardial infarction.Dec 31, 2023

Pubmed Data : Phytother Res. 2024 Jan ;38(1):384-399. Epub 2023 Nov 22. PMID: 37992723
Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Myocardial Infarction
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

Protective effect of Prunella vulgaris var. L extract against blue light induced damages in ARPE-19 cells and mouse retina.Dec 04, 2019

Pubmed Data : Free Radic Biol Med. 2019 Dec 5. Epub 2019 Dec 5. PMID: 31811921
Article Published Date : Dec 04, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Blue Light Toxicity, Macular Degeneration
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Photoprotective
Anti Therapeutic Actions : Blue Light (400−495 nm)
[+]

Prunella vulgaris aqueous extract has a protective effect on IL-1β-induced pancreatic β cell apoptosis and cytotoxicity.May 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2012 Jun ;3(6):919-924. Epub 2012 Mar 23. PMID: 22969993
Article Published Date : May 31, 2012
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Diabetes Mellitus: Type 1, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
Additional Keywords : Plant Extracts
[+]

Prunella vulgaris can improve the pregnancy outcomes of experimental autoimmune thyroiditis.Dec 23, 2021

Pubmed Data : J Reprod Immunol. 2021 Dec 24 ;149:103469. Epub 2021 Dec 24. PMID: 34979369
Article Published Date : Dec 23, 2021
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Thyroiditis: Autoimmune
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Prunella vulgaris exhibits anti-HSV-1 and HSV-2 activity. Sep 01, 2007

Pubmed Data : Antiviral Res. 2007 Sep;75(3):242-9. Epub 2007 Apr 17. PMID: 17475343
Article Published Date : Sep 01, 2007
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Genital Herpes, Herpes Labialis, HSV-1, HSV-2
Pharmacological Actions : Antiviral Agents
Additional Keywords : Plant Extracts
[+]

Prunella vulgaris has potential as a lung cancer chemopreventive agent.Dec 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2010 ;11(5):1355-8. PMID: 21198292
Article Published Date : Dec 31, 2009
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Chemopreventive
Additional Keywords : Phytotherapy, Plant Extracts
Problem Substances : Benzo(a)pyrene
[+]

Prunella vulgaris L. attenuates experimental autoimmune thyroiditis.Jul 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2020 Aug ;128:110288. Epub 2020 May 29. PMID: 32480225
Article Published Date : Jul 31, 2020
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Autoimmune Diseases, Thyroiditis: Autoimmune
Pharmacological Actions : Immunomodulatory
[+]

Prunella vulgaris L. attenuates gut dysbiosis and endotoxin leakage against alcoholic liver disease.Jan 29, 2024

Pubmed Data : J Ethnopharmacol. 2024 Jan 30 ;319(Pt 2):117237. Epub 2023 Sep 27. PMID: 37769885
Article Published Date : Jan 29, 2024
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Alcohol Toxicity , Alcoholic Liver Disease, Dysbiosis, Endotoxemia
Pharmacological Actions : Gastrointestinal Agents
[+]

Prunella vulgaris may enhance cognitive function via the activation of various intracellular signaling molecules and the up-regulation of adult hippocampal neurogenesis.Oct 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytother Res. 2015 Nov ;29(11):1814-21. Epub 2015 Sep 17. PMID: 26376910
Article Published Date : Oct 31, 2015
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Alzheimer's Disease, Schizophrenia
Pharmacological Actions : Neurogenesis, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Prunella vulgaris may prevent development of diabetic atherosclerosis.Dec 31, 2011

Pubmed Data : Am J Chin Med. 2012 ;40(5):937-51. PMID: 22928826
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Atherosclerosis, Diabetes Mellitus: Type 2, Hypertension
Pharmacological Actions : Hypoglycemic Agents, Malondialdehyde Down-regulation
Additional Keywords : Dose Response, Plant Extracts
[+]

Prunella vulgaris polysaccharides may interfere with hyperlipidaemia through anti-lipid peroxidation effects.May 05, 2020

Pubmed Data : Int J Biol Macromol. 2020 May 6 ;159:461-473. Epub 2020 May 6. PMID: 32387363
Article Published Date : May 05, 2020
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Hyperlipidemia
Pharmacological Actions : Antioxidants, Hypolipidemic
Additional Keywords : Polysaccharides
[+]

Root extract of Prunella vulgaris inhibits in vitro and in vivo carcinogenesis in MCF-5 human breast carcinoma.Feb 28, 2019

Pubmed Data : J BUON. 2019 Mar-Apr;24(2):549-554. PMID: 31128004
Article Published Date : Feb 28, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Breast Cancer
Pharmacological Actions : Angiogenesis Inhibitors, Anticarcinogenic Agents, Apoptotic, Cell cycle arrest, Chemopreventive
Additional Keywords : Plant Extracts
[+]

Sensitization to anoikis by pygenic acid A could be used as a new therapeutic strategy to control the metastasis of breast cancer.Nov 09, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2020 Nov 10 ;21(22). Epub 2020 Nov 10. PMID: 33182770
Article Published Date : Nov 09, 2020
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Breast Cancer
Pharmacological Actions : Anti-metastatic, Chemosensitizer
[+]

Spica prunellae extract has certain in vivo anti-tumour effect, which may be achieved through regulation of apoptosis related proteins.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Afr J Tradit Complement Altern Med. 2013 ;10(5):318-24. Epub 2013 Aug 12. PMID: 24311843
Article Published Date : Dec 31, 2012
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Acute T cell Leukemias
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Spica Prunellae may be a potential novel therapeutic agent for the treatment of cancers with constitutive activation of STAT3.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2013 ;13:144. Epub 2013 Jun 24. PMID: 23800091
Article Published Date : Dec 31, 2012
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Colorectal Cancer
Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative , Apoptotic, Vascular Endothelial Growth Factor A Inhibitor
Additional Keywords : Phytotherapy, Plant Extracts
[+]

The anti-inflammatory activity of P. vulgaris extract effectively attenuated the severity of intestinal inflammation in mdr1a-/- mice.Nov 05, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastrointest Pharmacol Ther. 2015 Nov 6 ;6(4):223-37. PMID: 26558156
Article Published Date : Nov 05, 2015
Study Type : Transgenic Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

The antitumour effect of Prunella vulgaris extract on thyroid cancer cells in vitro and in vivo.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:8869323. Epub 2021 Jan 8. PMID: 33505511
Article Published Date : Dec 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Thyroid Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative
[+]

The current study highlights P. vulgaris L. as an anti-dementia dietary supplement.Jan 17, 2017

Pubmed Data : J Agric Food Chem. 2017 Jan 18 ;65(2):291-300. Epub 2017 Jan 3. PMID: 28001065
Article Published Date : Jan 17, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Dementia
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents, Superoxide Dismutase Up-regulation
[+]

The therapeutic effects of Prunella vulgaris against fluoride-induced oxidative damage by using the metabolomics method.Jun 04, 2021

Pubmed Data : Environ Toxicol. 2021 Jun 5. Epub 2021 Jun 5. PMID: 34089294
Article Published Date : Jun 04, 2021
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Fluoride Toxicity
Pharmacological Actions : Antioxidants
Problem Substances : Fluoride, Sodium Fluoride
[+]

Triterpenic acid from Prunella vulgaris L. has an anti-diabetic effect, by controlling blood glucose and antioxidants.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin Med J (Engl). 2013 ;126(9):1647-53. PMID: 23652045
Article Published Date : Dec 31, 2012
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Diabetes Mellitus: Type 2, Hyperglycemia
Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Pancreato Protective Agents, Superoxide Dismutase Up-regulation
[+]

Wound healing acceleration and anti-inflammatory potential of Prunella vulgaris.Sep 14, 2022

Pubmed Data : J Ethnopharmacol. 2022 Sep 15 ;295:115411. Epub 2022 May 28. PMID: 35636653
Article Published Date : Sep 14, 2022
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

A hexane fraction of P. vulgaris var. lilacina may be a potent anti-inflammatory candidate.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2013 ;14(11):21489-503. Epub 2013 Oct 30. PMID: 24177568
Article Published Date : Dec 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Prostaglandin PGE2 downregulation
Additional Keywords : Plant Extracts
[+]

Anti-tumor effects and toxicity reduction mechanisms of Prunella vulgaris: A comprehensive review.Apr 17, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2024 Apr 18 ;29(8). Epub 2024 Apr 18. PMID: 38675663
Article Published Date : Apr 17, 2024
Study Type : Review
Additional Links
Substances : Prunella vulgaris
Diseases : Cancers: All
Pharmacological Actions : Angiogenesis Inhibitors, Apoptotic
Additional Keywords : Plant Extracts
[+]

Aqueous, as opposed to ethanol extract of Prunella vulgaris showed antiviral activity against HIV-1, primarily by inhibiting early events in the life cycle of the virus.Jan 01, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Virol J. 2011 ;8:188. Epub 2011 Apr 23. PMID: 21513560
Article Published Date : Jan 01, 2011
Study Type : Plant Study
Additional Links
Substances : Prunella vulgaris
Diseases : HIV Infections
Pharmacological Actions : Anti-HIV Agents
Additional Keywords : Plant Extracts, Water Versus Alcohol Extraction
[+]

Betulinic acid and ursolic acid have potential use as therapeutic agents against estrogen-dependent tumors.Aug 21, 2014

Pubmed Data : Biochem Biophys Res Commun. 2014 Aug 22 ;451(2):282-7. Epub 2014 Aug 1. PMID: 25088993
Article Published Date : Aug 21, 2014
Study Type : In Vitro Study
Additional Links
Substances : Betulinic acid, Prunella vulgaris, Ursolic Acid
Diseases : Breast Cancer, Breast Cancer: estrogen receptor alpha-positive, Prostate Cancer
Pharmacological Actions : Estrogen Receptor Modulators
[+]

Bioactive components in prunella vulgaris for treating Hashimoto's disease.Aug 29, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Heliyon. 2024 Aug 30 ;10(16):e36103. Epub 2024 Aug 13. PMID: 39253271
Article Published Date : Aug 29, 2024
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Hashimoto's thyroiditis
Pharmacological Actions : Immunomodulatory
[+]

Bioassay-guided isolation of an abetiane-type diterpenoid from Prunella vulgaris That protects against concanavalin A-induced autoimmune hepatitis.Jan 26, 2021

Pubmed Data : J Nat Prod. 2021 08 27 ;84(8):2189-2199. Epub 2021 Aug 12. PMID: 34383500
Article Published Date : Jan 26, 2021
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Autoimmune Diseases, Hepatitis, Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective
Problem Substances : Concanavalin A
[+]

Cannabis sativa, Prunella vulgaris and Withania somnifera possess anti-inflammatory, anti-arthritic and anti-rheumatic properties.Apr 18, 2017

Pubmed Data : J Mol Graph Model. 2017 Apr 19 ;74:296-304. Epub 2017 Apr 19. PMID: 28472734
Article Published Date : Apr 18, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ashwagandha, Cannabis, Prunella vulgaris
Diseases : Inflammation, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Emerging therapeutic role of Prunella vulgaris in thyroid disease.Jun 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin Herb Med. 2022 Jul ;14(3):403-413. Epub 2022 May 24. PMID: 36118009
Article Published Date : Jun 30, 2022
Study Type : Review
Additional Links
Substances : Prunella vulgaris
Diseases : Thyroid Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Exogenous melatonin enhances the yield and secondary metabolite contents of Prunella vulgaris.Mar 01, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Plants (Basel). 2023 Mar 2 ;12(5). Epub 2023 Mar 2. PMID: 36903989
Article Published Date : Mar 01, 2023
Study Type : Plant Study
Additional Links
Substances : Melatonin, Prunella vulgaris
[+]

Extracts of Prunella vulgaris L.have multi-target and multi-pathway effects on lung adenocarcinoma.Jul 21, 2014

Pubmed Data : Zhonghua Yi Xue Za Zhi. 2014 Jul 22 ;94(28):2216-21. PMID: 25331476
Article Published Date : Jul 21, 2014
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Lung Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Cell cycle arrest
Additional Keywords : Plant Extracts
[+]

Fallopia Japonica and Prunella vulgaris inhibit myopia progression.Oct 13, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Med Ther. 2022 Oct 14 ;22(1):271. Epub 2022 Oct 14. PMID: 36242032
Article Published Date : Oct 13, 2022
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Inflammation, Myopia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Identification and evaluation of the inhibitory effect of Prunella vulgaris extract on SARS-coronavirus 2 virus entry.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2021 ;16(6):e0251649. Epub 2021 Jun 9. PMID: 34106944
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Coronavirus Infection
Pharmacological Actions : Antiviral Agents
Additional Keywords : Plant Extracts
[+]

Innate immune-modulatory activity of Prunella vulgaris in thyrocytes functions as a potential mechanism for treating Hashimoto's thyroiditis.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Endocrinol (Lausanne). 2020 ;11:579648. Epub 2020 Nov 16. PMID: 33304319
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Hashimoto's thyroiditis
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Immunomodulatory
[+]

Melissa, Sweet Basil, Perilla, Prunella vulgaris and Savory has anti-HIV-1 activity. Jan 01, 1986

Pubmed Data : Zh Mikrobiol Epidemiol Immunobiol. 1986 Jan;(1):62-5. PMID: 9743251
Article Published Date : Jan 01, 1986
Study Type : In Vitro Study
Additional Links
Substances : Basil: Sweet, Melissa (Lemonbalm), Perilla , Prunella vulgaris, Savory
Diseases : HIV Infections
Pharmacological Actions : Reverse Transcriptase Inhibitors
Additional Keywords : Plant Extracts
[+]

Network pharmacology to explore the molecular mechanisms of Prunella vulgaris for treating Hashimoto's Thyroiditis.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2021 ;12:700896. Epub 2021 Oct 6. PMID: 34690752
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Kaempferol, Luteolin, Prunella vulgaris
Diseases : Hashimoto's thyroiditis
Pharmacological Actions : Immunomodulatory
[+]

Network pharmacology to explore the molecular mechanisms of Prunella vulgaris for treating thyroid cancer.Nov 09, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicine (Baltimore). 2023 Nov 10 ;102(45):e34871. PMID: 37960775
Article Published Date : Nov 09, 2023
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Thyroid Cancer
Pharmacological Actions : Antioxidants, Immunomodulatory
[+]

P. vulgaris extract has a potential protective effect against UVB-induced photo aging and photo-inflammation.Jan 28, 2018

Pubmed Data : Rejuvenation Res. 2018 Jan 29. Epub 2018 Jan 29. PMID: 29378470
Article Published Date : Jan 28, 2018
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Ultraviolet Radiation Induced Damage
Pharmacological Actions : Anti-Inflammatory Agents, Photoprotective
[+]

P. vulgaris L has marked anti- uterine myoma activity.Jun 17, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Med Ther. 2020 Jun 18 ;20(1):189. Epub 2020 Jun 18. PMID: 32552673
Article Published Date : Jun 17, 2020
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Myoma
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Survivin Down-Regulation
[+]

P. vulgaris possesses antiinflammatory properties and can regulate TNF-α-induced expression of adhesion molecules.Jun 30, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMB Rep. 2013 Jul ;46(7):352-7. PMID: 23884101
Article Published Date : Jun 30, 2013
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Atherosclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Anticholesteremic Agents, Hypolipidemic, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

P. vulgaris var. lilacina extract and its fractions have strong antioxidant and anticancer activities in vitro. Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2013 ;13:310. Epub 2013 Nov 9. PMID: 24206840
Article Published Date : Dec 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Cervical Cancer, Colon Cancer, Liver Cancer, Lung Cancer, Stomach Cancer
Pharmacological Actions : Antineoplastic Agents, Antioxidants, Apoptotic, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Plant Extracts
[+]

Pentacyclic triterpenoids from spikes of Prunella vulgaris L. with thyroid tumour cell cytostatic bioactivities.Jan 17, 2022

Pubmed Data : Nat Prod Res. 2022 Jan 18:1-9. Epub 2022 Jan 18. PMID: 35038938
Article Published Date : Jan 17, 2022
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Thyroid Cancer
Pharmacological Actions : Antiproliferative
[+]

Prunella possess antiviral, antibacterial, anti-inflammatory, immunoregulatory, anti-oxidative, anti-tumor, antihypertensive and hypoglycemic functions.Jul 31, 2016

Pubmed Data : Food Chem. 2016 Aug 1 ;204:483-96. Epub 2016 Feb 16. PMID: 26988527
Article Published Date : Jul 31, 2016
Study Type : Review
Additional Links
Substances : Prunella vulgaris
Diseases : Inflammation
Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents, Antihypertensive Agents, Antioxidants, Antiviral Agents, Immunomodulatory
[+]

Prunella vulgaris could be an effective therapeutic candidate against diabetes-associated cardiovascular diseases.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2013 ;2013:936463. Epub 2013 Sep 12. PMID: 24159354
Article Published Date : Dec 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Atherosclerosis, Cardiovascular Diseases, Diabetic Complications
Pharmacological Actions : Antioxidants, Antiproliferative , Heme oxygenase-1 up-regulation, NF-E2-Related Factor-2 (Nrf2) Modulator
Additional Keywords : Plant Extracts
[+]

Prunella vulgaris has the potential to be a future therapeutic agent for well-differentiated thyroid carcinoma. Jul 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2017 Aug ;14(2):1309-1314. Epub 2017 Jun 6. PMID: 28808482
Article Published Date : Jul 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Thyroid Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Prunella vulgaris inhibits HIV-1 infection. Mar 01, 1992

Pubmed Data : Virology. 1992 Mar;187(1):56-62. PMID: 1371029
Article Published Date : Mar 01, 1992
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : HIV Infections
[+]

Prunella vulgaris is an effective dietary chemopreventive agent with antimetastatic activity against malignant tumors.Oct 31, 2015

Pubmed Data : Oncol Rep. 2015 Nov ;34(5):2445-50. Epub 2015 Aug 21. PMID: 26324883
Article Published Date : Oct 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Cancer Metastasis, Cancers: All
Pharmacological Actions : Anti-metastatic, Chemopreventive, NF-kappaB Inhibitor
[+]

Prunella vulgaris L. attenuates experimental autoimmune thyroiditis.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2021 ;15:4559-4574. Epub 2021 Nov 4. PMID: 34764638
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Thyroiditis: Autoimmune
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Prunella vulgaris L: Critical pharmacological, expository traditional uses and extensive phytochemistry.Feb 02, 2021

Pubmed Data : Curr Drug Discov Technol. 2021 Feb 3. Epub 2021 Feb 3. PMID: 33538676
Article Published Date : Feb 02, 2021
Study Type : Review
Additional Links
Substances : Prunella vulgaris
Diseases : Cancers: All, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antimicrobial, Cardioprotective, Immunosuppressive Agents
[+]

Prunella vulgaris may have the therapeutic potential to inhibit the migration and invasion of liver cancer.Dec 31, 2015

Pubmed Data : Am J Chin Med. 2016 ;44(4):835-49. Epub 2016 May 24. PMID: 27222069
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Liver Cancer
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors
Additional Keywords : Tumor Microenvironment
[+]

Prunella vulgaris polysaccharide inhibits growth and migration of breast carcinoma-associated fibroblasts.Aug 31, 2016

Pubmed Data : Chin J Integr Med. 2016 Sep 1. Epub 2016 Sep 1. PMID: 27586473
Article Published Date : Aug 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Breast Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
Additional Keywords : Polysaccharides
[+]

Prunella vulgaris polysaccharide inhibits herpes simplex virus infection.Jan 07, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin Med. 2024 Jan 8 ;19(1):6. Epub 2024 Jan 8. PMID: 38185640
Article Published Date : Jan 07, 2024
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Herpes Simplex Virus Type 1, Herpes Simplex Virus Type 2
Pharmacological Actions : Anti-Inflammatory Agents, Antiviral Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Prunella vulgaris protects glucocorticoids-induced osteogenesis inhibition in bone marrow mesenchymal stem cells. Apr 30, 2020

Pubmed Data : Eur Rev Med Pharmacol Sci. 2020 May ;24(10):5691-5696. PMID: 32495904
Article Published Date : Apr 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Mesenchymal Stem Cells
[+]

Prunella vulgaris total flavonoids have an obvious anti-hepatocarcinoma effect.Jun 11, 2021

Pubmed Data : J Ethnopharmacol. 2021 Jun 12 ;273:113891. Epub 2021 Mar 4. PMID: 33675913
Article Published Date : Jun 11, 2021
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, Autophagy Up-regulation, Bcl-2 protein down-regulation
[+]

Research on the anti-ageing mechanism of Prunella vulgaris.Jul 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2023 Jul 31 ;13(1):12398. Epub 2023 Jul 31. PMID: 37524842
Article Published Date : Jul 30, 2023
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Aging
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Safety and efficacy of Prunella vulgaris preparation in adjuvant treatment of thyroid nodules.Oct 14, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicine (Baltimore). 2021 Oct 15 ;100(41):e27490. PMID: 34731129
Article Published Date : Oct 14, 2021
Study Type : Review
Additional Links
Substances : Prunella vulgaris
Diseases : Thyroid Nodule
[+]

Screening, identification and activity evaluation of pancreatic lipase inhibition in Prunella vulgaris.Nov 30, 2018

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2018 Dec ;43(23):4665-4671. PMID: 30717556
Article Published Date : Nov 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Pharmacological Actions : Enzyme Inhibitors: Pancreatic Lipase
[+]

Spica Prunellae can suppress the growth of HCT-8 cells.Aug 31, 2017

Pubmed Data : Oncol Rep. 2017 Sep ;38(3):1895-1901. Epub 2017 Jul 6. PMID: 28713966
Article Published Date : Aug 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative , MicroRNA modulator
Additional Keywords : Dose Response
[+]

Spica Prunellae inhibits the proliferation of colon cancer cells through G1/S cell cycle arrestSep 30, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2013 Oct ;6(4):1123-1127. Epub 2013 Aug 5. PMID: 24137475
Article Published Date : Sep 30, 2013
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest, Cyclin D1 Down-Regulation
Additional Keywords : Dose Response, Plant Extracts
[+]

Synergistic effects of multiple components, targets, and pathways on the anti-BRCA activity of P. vulgaris.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:5481563. Epub 2022 Aug 10. PMID: 35990843
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative
[+]

Tannin from the herbs Prunella vulgaris and Rhizoma cibotte may responsible for anti-HIV activity. Aug 30, 2002

Pubmed Data : Life Sci. 2002 Aug 30;71(15):1779-91. PMID: 12151056
Article Published Date : Aug 30, 2002
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris, Rhizoma cibotte
Diseases : HIV Infections
Pharmacological Actions : Antiviral Agents
Additional Keywords : Plant Extracts
[+]

The aqueous extract of Prunella vulgaris suppresses cell invasion and migration in human liver cancer cellsDec 31, 2011

Pubmed Data : Am J Chin Med. 2012 ;40(3):643-56. PMID: 22745076
Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Liver Cancer
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords : Phytotherapy, Plant Extracts
[+]

The results indicated that the growth of lung cancer cells A549 might be inhibited with Spica prunellae through activating the proapoptotic protein caspase-3.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cancer Res Ther. 2018 ;14(4):760-763. PMID: 29970649
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Lung Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

This study clarified that mangiferin, rosmarinic acid and salviaflaside were considered as the anti-insomnia components of P. vulgaris.Oct 27, 2021

Pubmed Data : J Ethnopharmacol. 2021 Oct 28 ;279:114373. Epub 2021 Jun 26. PMID: 34181959
Article Published Date : Oct 27, 2021
Study Type : Review
Additional Links
Substances : Mangiferin, Prunella vulgaris, Rosmarinic acid
Diseases : Insomnia
[+]

Vulgarisin-type diterpenoids from self-heal ( Prunella vulgaris) and their neuroprotective effects against ischemia/reperfusion.Jul 03, 2022

Pubmed Data : Food Funct. 2022 Jul 4 ;13(13):7062-7074. Epub 2022 Jul 4. PMID: 35678758
Article Published Date : Jul 03, 2022
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Cerebral Ischemia
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Water extracts of Prunella Vulgaris demonstrate potent anti-lentiviral activity against Equinine Infectious Anemia virus. Jan 20, 2009

Pubmed Data : Virol J. 2009 Jan 20;6:8. PMID: 19154592
Article Published Date : Jan 20, 2009
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Equine infectious anemia, Lentivirus Infection
[+]

Water-extracted Prunella vulgaris alleviates endometriosis by reducing aerobic glycolysis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:872810. Epub 2022 Apr 4. PMID: 35444541
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Endometriosis
Pharmacological Actions : Anti-Inflammatory Agents

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