Puerarin

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182 Diseases Researched for Puerarin
NameACCKFocus
Osteoporosis1139Locked
Oxidative Stress1632Locked
Inflammation1431Locked
Lipopolysaccharide-Induced Toxicity1629Locked
Diabetes Mellitus: Type 21324Locked
Chemically-Induced Liver Damage1323Locked
Coronavirus Infection523Locked
Burns322Locked
Myocardial Infarction518Locked
Obesity518Locked
Parkinson's Disease1018Locked
Coronary Artery Disease317Locked
Alzheimer's Disease1116Locked
Cardiovascular Diseases915Locked
Myocardial Fibrosis 615Locked
Alcoholic Liver Disease714Locked
Myocardial Ischemia814Locked
Osteoarthritis814Locked
Subarachnoid hemorrhage314Locked
Atherosclerosis613Locked
Cadmium Poisoning 813Locked
Colon Cancer313Locked
Diabetic Nephropathy713Locked
Stroke: Ischemic313Locked
Alcohol Toxicity 612Locked
Diabetic Complications712Locked
Hypertension712Locked
Metabolic Diseases212Locked
Sepsis512Locked
C-Reactive Protein211Locked
Insulin Resistance711Locked
Polycystic Ovary Syndrome211Locked
Alcohol Addiction110Locked
Asthma110Locked
Brain Ischemia510Locked
Chronic Pain110Locked
Hantavirus Infections110Locked
Lipid Peroxidation510Locked
Liver Fibrosis510Locked
Neurodegenerative Diseases610Locked
Depression59Locked
Hypoxia69Locked
Spinal Cord Injuries59Locked
Diabetic Retinopathy58Locked
Lung Cancer68Locked
Cerebral Ischemia47Locked
Hydrogen Peroxide Induced Toxicity67Locked
Liver Damage47Locked
Pre-Eclampsia27Locked
Cardiac Hypertrophy46Locked
Cognitive Decline/Dysfunction36Locked
Diabetes Mellitus: Type 146Locked
Heart Failure36Locked
Hypertension: Pulmonary36Locked
Lead Poisoning46Locked
Lung Injury: Acute26Locked
Middle Cerebral Artery Occlusion (MCAO)36Locked
Neuropathic Pain36Locked
Advanced Glycation End products (AGE)35Locked
Brain: Oxidative Stress45Locked
Breast Cancer35Locked
Cardiomyopathy35Locked
Cholesterol: Oxidation15Locked
Endothelial Dysfunction35Locked
Ischemia35Locked
Liver Cancer45Locked
Lung Damage25Locked
Ovarian Cancer35Locked
Thrombosis15Locked
Anxiety24Locked
Bladder Cancer44Locked
Cancers: Drug Resistant34Locked
Carcinoma: Non-Small-Cell Lung34Locked
Chemotherapy and Radiation Toxicity34Locked
Chemotherapy-Induced Toxicity: Cisplatin24Locked
Chemotherapy-Induced Toxicity: Paclitaxel24Locked
DNA damage34Locked
Dementia24Locked
Diabetes: Cataract24Locked
Diabetes: Oxidative Stress24Locked
Dyslipidemias24Locked
Fibrosis24Locked
Hepatic Steatosis24Locked
High Fat Diet24Locked
Kidney Damage24Locked
Liver Cirrhosis24Locked
Macular Degeneration24Locked
Memory Disorders24Locked
Peripheral Nerve Diseases24Locked
Retinal Diseases24Locked
Brain Inflammation 23Locked
Cancer Metastasis23Locked
Chemotherapy-Induced Toxicity: Doxorubicin13Locked
Colorectal Cancer33Locked
Diabetes: Cardiovascular Illness23Locked
Glaucoma23Locked
Heart Disease23Locked
Hyperglycemia23Locked
Sarcopenia23Locked
Ulcerative Colitis23Locked
Wound Healing23Locked
Allodynia12Locked
Aluminum Toxicity 12Locked
Arthritis12Locked
Atopic Dermatitis12Locked
Bisphenol Toxicity12Locked
Bone Diseases12Locked
Bone Fractures12Locked
Chemotherapy12Locked
Chemotherapy-Induced Kidney Damage12Locked
Chemotherapy-Induced Toxicity: Cyclophosphamide12Locked
Chemotherapy-Induced Toxicity: 5-fluorouracil 12Locked
Chemotherapy-Induced Toxicity: Gentamicin12Locked
Degenerative Disk Disease12Locked
Diarrhea: IBS associated12Locked
Drug Toxicity: Methotrexate12Locked
Endometriosis22Locked
Escherichia coli Infections12Locked
Esophageal Cancer12Locked
Fatty Liver12Locked
Fever12Locked
Fibroids: Uterine12Locked
Gestational Diabetes12Locked
Heart Disease: Ischemic12Locked
High Sugar Diet12Locked
Hyperalgesia12Locked
Hypercholesterolemia12Locked
Hyperlipidemia12Locked
Hypersensitivity12Locked
Hypoglycemia12Locked
Incontinence: Urinary12Locked
Infertility: Male12Locked
Intracerebral Hemorrhage12Locked
Kidney Failure: Chronic12Locked
Kidney Fibrosis12Locked
Leukemia: Acute myelogenous leukemia (AML) 22Locked
Mastitis12Locked
Mercury Poisoning12Locked
Mucositis12Locked
Muscle Atrophy 12Locked
Neuralgia12Locked
Nonalcoholic fatty liver disease (NAFLD)12Locked
Osteonecrosis12Locked
Pancreatitis: Chronic12Locked
Post-Traumatic Stress Disorders (PTSD)12Locked
Postmenopausal Disorders12Locked
Pulmonary Fibrosis22Locked
Staphylococcus aureus infection12Locked
Stroke: Attenuation/Recovery 12Locked
Testicular Injury: Cadmium-Induced12Locked
Ultraviolet Radiation Induced Damage22Locked
Vascular Calcification12Locked
Acute Respiratory Distress Syndrome11Locked
Aging Skin11Locked
Air Pollution Linked Toxicity11Locked
Aortic Aneurysm11Locked
Brain Hypoxia11Locked
Breast Cancer: Triple Negative 11Locked
Cancers: Multi-Drug Resistant11Locked
Central Nervous System Diseases11Locked
Cervical Cancer11Locked
Chondrosarcoma11Locked
Colitis11Locked
Endothelial Damage11Locked
Eye Diseases11Locked
Gout11Locked
Human Papillomavirus (HPV)11Locked
Influenza11Locked
Kidney Damage: Chemically-Induced11Locked
Leukemia11Locked
Leukemia: Acute promyelocytic leukemia 11Locked
Leukemia: Chronic myelogenous leukemia (CML) 11Locked
Metabolic Syndrome X11Locked
Oral Cancer11Locked
Ovarian Failure11Locked
Pancreatic Cancer11Locked
Peripheral Neuropathies11Locked
Promyelocytic leukemia 11Locked
Prostate Cancer11Locked
Retinoblastoma11Locked
Squamous cell carcinoma11Locked
Titanium Toxicity11Locked
91 Pharmacological Actions Researched for Puerarin
NameACCKFocus
Anti-Inflammatory Agents85180Locked
Neuroprotective Agents62122Locked
Antioxidants63120Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor3991Locked
Cardioprotective4790Locked
Anti-Apoptotic4878Locked
NF-kappaB Inhibitor3478Locked
Interleukin-6 Downregulation2450Locked
Osteoprotective 1850Locked
Hepatoprotective2648Locked
Interleukin-1 beta downregulation2444Locked
Apoptotic2437Locked
Anti-Fibrotic1836Locked
Renoprotective1834Locked
Antiproliferative 2531Locked
Analgesics526Locked
Hypoglycemic Agents1222Locked
Nrf2 activation1321Locked
Chemoprotective Agents1020Locked
MicroRNA modulator1320Locked
Antihypertensive Agents619Locked
Hypolipidemic1119Locked
Vasodilator Agents516Locked
Antiviral Agents514Locked
Immunomodulatory314Locked
Malondialdehyde Down-regulation714Locked
Gastrointestinal Agents713Locked
Superoxide Dismutase Up-regulation813Locked
Anticholesteremic Agents212Locked
Autophagy Up-regulation710Locked
Chemosensitizer610Locked
Hypoxia-inducible factor-1 (HIF-1) inhibitor110Locked
Anti-metastatic89Locked
Cyclooxygenase 2 Inhibitors69Locked
Antidepressive Agents48Locked
Autophagy Inhibitors47Locked
Cytoprotective67Locked
Heme oxygenase-1 up-regulation47Locked
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor37Locked
Anti-Anxiety Agents36Locked
Neuritogenic36Locked
Osteogenic36Locked
Chemotherapeutic35Locked
Interleukin-4 downregulation35Locked
Cell cycle arrest44Locked
Chondroprotective24Locked
Gastroprotective24Locked
Pancreato Protective Agents34Locked
Transforming growth factor beta (TGF-β) inhibitor34Locked
Chemopreventive33Locked
Insulin Sensitizers23Locked
Radioprotective23Locked
SIRT1 Activator23Locked
Vascular Endothelial Growth Factor Inhibitors33Locked
5-Lipoxygenase Inhibitor12Locked
Angiogenesis Inducing Agents12Locked
Anti-pyretic 12Locked
Bcl-2 protein down-regulation22Locked
Brain-derived neurotrophic factor modulator12Locked
Chelating Agents12Locked
Detoxifier12Locked
Gene Protective12Locked
Interferon Gamma Reducer12Locked
Interleukin-18 down-regulation12Locked
Matrix Metalloproteinase-13 (MMP-13) Inhibitor12Locked
Matrix metalloproteinase-3 (MMP-3) inhibitor12Locked
Neuroplasticity enhancement12Locked
Nitric Oxide Inhibitor12Locked
Photoprotective22Locked
Postaglandin PGE2 downregulation 12Locked
STAT3 Inhibitor12Locked
Transforming growth factor beta (TGF-β) upregulation12Locked
Vascular Endothelial Growth Factor A Enhancer12Locked
Vascular Endothelial Growth Factor Regulator12Locked
Wnt/β-catenin pathway down-regulation12Locked
Wnt/β-catenin signaling pathway modulation22Locked
Angiogenesis Modulating Agents11Locked
Anti-Glycation Agents11Locked
Antineoplastic Agents11Locked
Antinoceceptive 11Locked
Bax/Bcl2 ratio: Increase11Locked
Genoprotective11Locked
Heme oxygenase-1 inducer11Locked
Interleukin-2 Downregulation11Locked
Interleukin-8 downregulation11Locked
Matrix metalloproteinase-1 (MMP-1) inhibitor11Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor11Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor11Locked
Multidrug Resistance Gene Modulators11Locked
Neocardiogenic 11Locked
Protein Kinase Inhibitors11Locked

View the Evidence:
375 Abstracts with Puerarin Research

[+]

Puerarin induces apoptosis in A549 cells.May 07, 2017

Pubmed Data : Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2017 May 8 ;33(5):466-469. PMID: 29926595
Article Published Date : May 07, 2017
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Lung Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Puerarin induces apoptosis in prostate cancer cells via inactivation of the Keap1/Nrf2/ARE signaling pathway.Nov 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Bioengineered. 2021 Dec ;12(1):402-413. PMID: 33356808
Article Published Date : Nov 30, 2021
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Prostate Cancer
Pharmacological Actions : Apoptotic
[+]

Puerarin induces cell apoptosis in human chondrosarcoma cell line SW1353.Oct 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2017 Nov ;14(5):5585-5590. Epub 2017 Sep 6. PMID: 29113186
Article Published Date : Oct 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Chondrosarcoma
Pharmacological Actions : Apoptotic
[+]

Puerarin induces ferroptosis in colorectal cancer cells.Dec 31, 2022

Pubmed Data : Nutr Cancer. 2023 ;75(7):1571-1578. Epub 2023 Jun 1. PMID: 37260353
Article Published Date : Dec 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Colorectal Cancer
Pharmacological Actions : Apoptotic
[+]

Puerarin induces liver cancer cell apoptosis in a dose-dependent manner.Jul 31, 2017

Pubmed Data : Anticancer Res. 2017 Aug ;37(8):4425-4431. PMID: 28739736
Article Published Date : Jul 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Dose Response
[+]

Puerarin induces mouse mesenteric vasodilation and ameliorates hypertension involving endothelial TRPV4 channels.Nov 17, 2020

Pubmed Data : Food Funct. 2020 Nov 18 ;11(11):10137-10148. PMID: 33155599
Article Published Date : Nov 17, 2020
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents, Vasodilator Agents
[+]

Puerarin induces Nrf2 as a cytoprotective mechanism to prevent cadmium-induced autophagy inhibition and NLRP3 inflammasome activation.Feb 10, 2021

Pubmed Data : J Inorg Biochem. 2021 Feb 11 ;217:111389. Epub 2021 Feb 11. PMID: 33607539
Article Published Date : Feb 10, 2021
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Cadmium Poisoning , Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Cytoprotective, Hepatoprotective
[+]

Puerarin induces platinum-resistant epithelial ovarian cancer cell apoptosis by targeting SIRT1.Aug 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Int Med Res. 2021 Sep ;49(9):3000605211040762. PMID: 34590923
Article Published Date : Aug 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Cancers: Drug Resistant, Ovarian Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Puerarin inhibited cadmium induced apoptosis in rPT cells by ameliorating the mitochondrial dysfunction.Dec 24, 2016

Pubmed Data : Chem Biol Interact. 2016 Dec 25 ;260:219-231. Epub 2016 Oct 4. PMID: 27717697
Article Published Date : Dec 24, 2016
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Cadmium Poisoning
Pharmacological Actions : Anti-Apoptotic, Bax/Bcl2 ratio: Increase
Additional Keywords : Anti-Apoptotic, Bax/Bcl2, Cadmium, Cadmium Poisoning, Puerarin
Problem Substances : Cadmium
[+]

Puerarin inhibits DNA damage of HaCaT cells induced by UVB via ceramide pathway.Apr 30, 2012

Pubmed Data : Yao Xue Xue Bao. 2012 May ;47(5):609-13. PMID: 22812004
Article Published Date : Apr 30, 2012
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : DNA damage, Ultraviolet Radiation Induced Damage
Pharmacological Actions : Photoprotective
[+]

Puerarin inhibits inflammation and attenuates endothelial insulin resistance.Apr 30, 2012

Pubmed Data : Biochimie. 2012 May ;94(5):1143-50. Epub 2012 Feb 1. PMID: 22314193
Article Published Date : Apr 30, 2012
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Inflammation, Insulin Resistance
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Puerarin inhibits NLRP3-caspase-1-GSDMD-mediated pyroptosis via P2X7 receptor in cardiomyocytes and macrophages.Aug 23, 2023

Pubmed Data : Int J Mol Sci. 2023 Aug 24 ;24(17). Epub 2023 Aug 24. PMID: 37685976
Article Published Date : Aug 23, 2023
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Diabetes: Cardiovascular Illness
Pharmacological Actions : Cardioprotective
[+]

Puerarin inhibits proliferation and induces apoptosis by up-regulation of miR-16 in bladder cancer cell line T24.Feb 07, 2018

Pubmed Data : Oncol Res. 2018 Feb 8. Epub 2018 Feb 8. PMID: 29422113
Article Published Date : Feb 07, 2018
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Bladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cyclooxygenase 2 Inhibitors, MicroRNA modulator, NF-kappaB Inhibitor
[+]

Puerarin inhibits the PERK-eIF2-ATF4-CHOP pathway through Inactivating JAK2/STAT3 signal in pancreatic beta-cells. Sep 05, 2021

Pubmed Data : Am J Chin Med. 2021 Sep 6:1-16. Epub 2021 Sep 6. PMID: 34488550
Article Published Date : Sep 05, 2021
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Anti-Apoptotic
[+]

Puerarin inhibits the progression of bladder cancer.Oct 04, 2020

Pubmed Data : Cancer Biother Radiopharm. 2020 Oct 5. Epub 2020 Oct 5. PMID: 33016781
Article Published Date : Oct 04, 2020
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Bladder Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , MicroRNA modulator
[+]

Puerarin inhibits the proliferation,invasion,and migration of non-small cell lung cancer cells.Jan 31, 2022

Pubmed Data : Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2022 Feb ;44(1):91-101. PMID: 35300770
Article Published Date : Jan 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer
Pharmacological Actions : Antiproliferative , MicroRNA modulator
[+]

Puerarin inhibits titanium particle-induced osteolysis and RANKL-induced osteoclastogenesis.Sep 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2020 Oct ;24(20):11972-11983. Epub 2020 Sep 7. PMID: 32896108
Article Published Date : Sep 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Titanium Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Titanium Nanoparticles
[+]

Puerarin is a potential therapeutic agent for lung cancer.Mar 31, 2018

Pubmed Data : Oncol Rep. 2018 Apr ;39(4):1731-1738. Epub 2018 Jan 26. PMID: 29393465
Article Published Date : Mar 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Lung Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Up-regulation
[+]

Puerarin is able to enhance SOD activity, and inhibit RAGE and VEGF expressions in retinas of STZ-induced early diabetic rats.Oct 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Trop Med. 2012 Nov ;5(11):891-6. PMID: 23146804
Article Published Date : Oct 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Advanced Glycation End products (AGE), Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Superoxide Dismutase Up-regulation, Vascular Endothelial Growth Factor Inhibitors
[+]

Puerarin may act as an intracellular ROS scavenger, and protect neurons against oxidative-stress-induced apoptosis.Dec 31, 2010

Pubmed Data : Exp Gerontol. 2011 Jan ;46(1):30-7. Epub 2010 Oct 13. PMID: 20933077
Article Published Date : Dec 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Brain: Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
[+]

Puerarin may be a potential cardioprotective agent for use in the clinical treatment of cardiomyopathy triggered by daunorubicin.Nov 30, 2017

Pubmed Data : Int J Mol Med. 2017 Dec ;40(6):1889-1894. Epub 2017 Oct 12. PMID: 29039532
Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Chemotherapy and Radiation Toxicity
Pharmacological Actions : Anti-Apoptotic, Cardioprotective, Chemoprotective Agents
[+]

Puerarin may be a potential neuroprotective drug in the clinical treatment of neuroinflammation via anti-apoptotic mechanisms.Jun 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2017 Jul ;14(1):813-818. Epub 2017 Jun 6. PMID: 28673004
Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Puerarin may be effective in preventing islet cells from the toxic action of reactive oxygen species in diabetes.Jan 03, 2006

Pubmed Data : Eur J Pharmacol. 2006 Jan 4 ;529(1-3):1-7. PMID: 16321378
Article Published Date : Jan 03, 2006
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Hydrogen Peroxide Induced Toxicity
Pharmacological Actions : Anti-Apoptotic, Pancreato Protective Agents, Superoxide Dismutase Up-regulation
Problem Substances : Insulin
[+]

Puerarin may exert protective effects against Alzheimer's disease.Nov 30, 2017

Pubmed Data : Mol Med Rep. 2017 Dec ;16(6):9081-9085. Epub 2017 Oct 3. PMID: 28990074
Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents, Wnt/β-catenin signaling pathway modulation
[+]

Puerarin may have neuroprotective effect through activation of the PI3K/Akt signalling pathway.Apr 30, 2012

Pubmed Data : Cell Biol Int. 2012 May 1 ;36(5):419-26. PMID: 22126839
Article Published Date : Apr 30, 2012
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Hydrogen Peroxide Induced Toxicity, Oxidative Stress
Pharmacological Actions : Neuroprotective Agents
[+]

Puerarin may improve the survival of female reproductive stem cells and play a protective role against premature ovarian failure.Sep 28, 2020

Pubmed Data : Reprod Sci. 2020 Sep 29. Epub 2020 Sep 29. PMID: 32996063
Article Published Date : Sep 28, 2020
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Ovarian Failure
Pharmacological Actions : Antioxidants, Nrf2 activation, Wnt/β-catenin signaling pathway modulation
[+]

Puerarin may represent a chemopreventive and chemotherapeutic agent for liver cancer treatment.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Braz J Med Biol Res. 2020 ;53(4):e8882. Epub 2020 Mar 31. PMID: 32294699
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Liver Cancer
Pharmacological Actions : Anti-metastatic, Chemopreventive, MicroRNA modulator
[+]

Puerarin may support myocardial regenerative processes. Dec 31, 2013

Pubmed Data : Cell Physiol Biochem. 2014 ;34(2):383-92. Epub 2014 Jul 11. PMID: 25059232
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Isoflavones, Puerarin
Pharmacological Actions : Neocardiogenic
Additional Keywords : Myocardial Regeneration
[+]

Puerarin might suppress the fine particulate matter-induced vascular smooth muscle cell proliferation.May 03, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2018 May 4 ;18(1):146. Epub 2018 May 4. PMID: 29728095
Article Published Date : May 03, 2018
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Air Pollution Linked Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Puerarin prevented lipopolysaccharide-induced vascular endothelial injury.May 14, 2018

Pubmed Data : Biomed Pharmacother. 2018 May 15 ;104:261-267. Epub 2018 May 15. PMID: 29775893
Article Published Date : May 14, 2018
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Endothelial Damage, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-8 downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Puerarin prevents acute lver injury.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2021 ;12:727916. Epub 2021 Aug 6. PMID: 34421621
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Inflammation, Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Puerarin prevents cadmium-induced hepatic cell damage by suppressing apoptosis and restoring autophagic flux.May 02, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 May 3 ;115:108929. Epub 2019 May 3. PMID: 31060001
Article Published Date : May 02, 2019
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Antioxidants, Hepatoprotective
Problem Substances : Cadmium
[+]

Puerarin prevents cadmium-induced mitochondrial fission in AML-12 cells via Sirt1-dependent pathway.Dec 14, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2022 Dec 15 ;248:114302. Epub 2022 Nov 16. PMID: 36399995
Article Published Date : Dec 14, 2022
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Hepatoprotective
Problem Substances : Cadmium
[+]

Puerarin prevents LPS-induced acute lung injury via inhibiting inflammatory response.Mar 19, 2018

Pubmed Data : Microb Pathog. 2018 Mar 20 ;118:170-176. Epub 2018 Mar 20. PMID: 29571724
Article Published Date : Mar 19, 2018
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Anti-Inflammatory Agents, Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute, Puerarin, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Puerarin produced a significant protection against lead induced mitochondrial apoptosis.Apr 26, 2016

Pubmed Data : Biol Trace Elem Res. 2016 Apr 27. Epub 2016 Apr 27. PMID: 27116952
Article Published Date : Apr 26, 2016
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Lead Poisoning
Pharmacological Actions : Anti-Apoptotic, Cytoprotective
[+]

Puerarin promotes DUSP1 expression by regulating miR‑133a‑3p in breast cancer.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2019 Jan ;19(1):205-212. Epub 2018 Nov 21. PMID: 30483784
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Puerarin promotes MIN6 cell survival by reducing cellular reactive oxygen species.Apr 30, 2018

Pubmed Data : Mol Med Rep. 2018 May ;17(5):7281-7286. Epub 2018 Mar 14. PMID: 29568901
Article Published Date : Apr 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Antioxidants, Pancreato Protective Agents
[+]

Puerarin protects against H 2 O 2-induced apoptosis of HTR-8/SVneo cells.Jul 05, 2022

Pubmed Data : Placenta. 2022 Jul 6 ;126:202-208. Epub 2022 Jul 6. PMID: 35870270
Article Published Date : Jul 05, 2022
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Hydrogen Peroxide Induced Toxicity
Pharmacological Actions : Anti-Apoptotic, MicroRNA modulator
[+]

Puerarin protects against high glucose-induced acute vascular dysfunction.Feb 28, 2009

Pubmed Data : Vascul Pharmacol. 2009 Mar-Apr;50(3-4):110-5. Epub 2008 Nov 24. PMID: 19073281
Article Published Date : Feb 28, 2009
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Endothelial Dysfunction
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation
Additional Keywords : Antioxidants, endothelial dysfunction, Heme oxygenase-1 up-regulation, Puerarin
[+]

Puerarin protects against human retinal endothelial cells injury induced by high glucose.Apr 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Gen Physiol Biophys. 2021 May ;40(3):235-243. PMID: 34100379
Article Published Date : Apr 30, 2021
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Diabetic Retinopathy
Pharmacological Actions : Anti-Apoptotic, MicroRNA modulator
[+]

Puerarin protects dopaminergic neurons against 6-hydroxydopamine neurotoxicity.Oct 31, 2010

Pubmed Data : Planta Med. 2010 Nov ;76(16):1820-6. Epub 2010 May 27. PMID: 20509103
Article Published Date : Oct 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Puerarin protects endothelial progenitor cells from damage of angiotensin II.Feb 28, 2018

Pubmed Data : Mol Med Rep. 2018 Mar ;17(3):3877-3883. Epub 2017 Dec 19. PMID: 29359784
Article Published Date : Feb 28, 2018
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Atherosclerosis
Pharmacological Actions : Antioxidants, Nrf2 activation
[+]

Puerarin protects PC12 cells against beta-amyloid-induced cell injury.Sep 30, 2008

Pubmed Data : Cell Biol Int. 2008 Oct ;32(10):1230-7. Epub 2008 Jul 16. PMID: 18675923
Article Published Date : Sep 30, 2008
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Brain: Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Antioxidants, Brain: Oxidative Stress, Neuroprotective Agents, Puerarin
[+]

Puerarin protects pulmonary arteries from hypoxic injury.May 06, 2019

Pubmed Data : Pharmacol Rep. 2019 May 7 ;71(5):855-861. Epub 2019 May 7. PMID: 31408784
Article Published Date : May 06, 2019
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Hypoxia
Pharmacological Actions : Antioxidants
[+]

Puerarin protects pulmonary arteries from hypoxic injury.Aug 31, 2019

Pubmed Data : Pharmacol Rep. 2019 Sep ;71(5):855-861. Epub 2019 May 7. PMID: 31994047
Article Published Date : Aug 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Hypoxia
Pharmacological Actions : Antioxidants
[+]

Puerarin protects vascular smooth muscle cells from oxidized low-density lipoprotein-induced reductions in viability.Nov 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2020 Dec ;20(6):270. Epub 2020 Oct 27. PMID: 33199995
Article Published Date : Nov 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Atherosclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Hypolipidemic, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Puerarin rebuilding the mucus layer and regulating mucin-utilizing bacteria to relieve ulcerative colitis. Oct 13, 2020

Pubmed Data : J Agric Food Chem. 2020 Oct 14 ;68(41):11402-11411. Epub 2020 Sep 14. PMID: 32864960
Article Published Date : Oct 13, 2020
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Ulcerative Colitis
Pharmacological Actions : Gastrointestinal Agents
[+]

Puerarin reduces oxidative damage and photoaging caused by UVA radiation.Nov 08, 2022

Pubmed Data : Nutrients. 2022 Nov 9 ;14(22). Epub 2022 Nov 9. PMID: 36432411
Article Published Date : Nov 08, 2022
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Aging Skin, Oxidative Stress, Ultraviolet Radiation Induced Damage
Pharmacological Actions : Antioxidants, Matrix metalloproteinase-1 (MMP-1) inhibitor, Nrf2 activation, Photoprotective
[+]

Puerarin regulated the proliferation and apoptosis of pulmonary fibrosis cells.Aug 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Sci Monit. 2019 Aug 31 ;25:6523-6531. Epub 2019 Aug 31. PMID: 31471534
Article Published Date : Aug 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Acute Respiratory Distress Syndrome, Pulmonary Fibrosis
Pharmacological Actions : Anti-Fibrotic, Interleukin-2 Downregulation, Interleukin-4 downregulation, Transforming growth factor beta (TGF-β) inhibitor
[+]

Puerarin restored the impaired autophagic flux in lead-treated rat proximal tubular (rPT) cells.Oct 19, 2016

Pubmed Data : J Biochem Mol Toxicol. 2016 Oct 20. Epub 2016 Oct 20. PMID: 27762461
Article Published Date : Oct 19, 2016
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Kidney Damage: Chemically-Induced, Lead Poisoning
Pharmacological Actions : Renoprotective
Problem Substances : Lead
[+]

Puerarin restores the autophagic flux to alleviate cadmium‑induced endoplasmic reticulum stress in NRK‑52E cells.Aug 31, 2020

Pubmed Data : Mol Med Rep. 2020 Sep ;22(3):2551-2563. Epub 2020 Jul 6. PMID: 32705200
Article Published Date : Aug 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Cadmium Poisoning
Pharmacological Actions : Antioxidants, Nrf2 activation
Problem Substances : Cadmium
[+]

Puerarin reverses cadmium-induced lysosomal dysfunction in primary rat proximal tubular cells.Mar 31, 2019

Pubmed Data : Biochem Pharmacol. 2019 Apr ;162:132-141. Epub 2018 Oct 19. PMID: 30347204
Article Published Date : Mar 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Cadmium Poisoning
Pharmacological Actions : Cytoprotective
[+]

Puerarin sensitized K562/ADR cells by inhibiting NF-κB pathway and inducing autophagy.Nov 02, 2020

Pubmed Data : Phytother Res. 2020 Nov 3. Epub 2020 Nov 3. PMID: 33141989
Article Published Date : Nov 02, 2020
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Leukemia: Acute myelogenous leukemia (AML)
Pharmacological Actions : Autophagy Up-regulation, Chemosensitizer
[+]

Puerarin suppresses cell growth and migration in HPV-positive cervical cancer cells.Jun 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2019 Jul ;18(1):543-549. Epub 2019 May 17. PMID: 31258692
Article Published Date : Jun 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Cervical Cancer, Human Papillomavirus (HPV)
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Puerarin suppresses glycolysis and increases cisplatin chemosensitivity in oral squamous cell carcinoma.Dec 31, 2022

Pubmed Data : Nutr Cancer. 2023 ;75(3):1028-1037. Epub 2023 Jan 31. PMID: 36718661
Article Published Date : Dec 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Oral Cancer, Squamous cell carcinoma
Pharmacological Actions : Antiproliferative , Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Cisplatin
[+]

Puerarin suppresses invasion and vascularization of endometriosis tissue stimulated by 17β-estradiol.Dec 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2011 ;6(9):e25011. Epub 2011 Sep 15. PMID: 21949833
Article Published Date : Dec 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Endometriosis
Pharmacological Actions : Vascular Endothelial Growth Factor Inhibitors
[+]

Puerarin was demonstrated to inhibit the viability of human bladder cancer cells.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2018 Jan ;15(1):167-174. Epub 2017 Oct 31. PMID: 29375709
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Bladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Puerarin will be a promising agent that prevents or slows osteoporosis.Jul 14, 2013

Pubmed Data : Phytomedicine. 2013 Jul 15 ;20(10):787-96. Epub 2013 Apr 29. PMID: 23639192
Article Published Date : Jul 14, 2013
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Osteoporosis
Pharmacological Actions : Anti-Apoptotic, Osteoprotective
[+]

Puerarin, the predominant isoflavone found within kudzu, inhibits aging of endothelial progenitor cells. Aug 01, 2008

Pubmed Data : Vascul Pharmacol. 2008 Aug-Sep;49(2-3):106-10. Epub 2008 Jul 20. PMID: 18692596
Article Published Date : Aug 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Kudzu, Puerarin
Additional Keywords : Endothelial Progenitor Cells
[+]

Puerarin-an isoflavone with beneficial effects on bone health.Dec 29, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Biosci (Landmark Ed). 2021 Dec 30 ;26(12):1653-1667. PMID: 34994179
Article Published Date : Dec 29, 2021
Study Type : Review
Additional Links
Substances : Puerarin
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

Puerarin: A protective drug against ischemia-reperfusion injury.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:927611. Epub 2022 Aug 24. PMID: 36091830
Article Published Date : Dec 31, 2021
Study Type : Review
Additional Links
Substances : Puerarin
Diseases : Ischemia
Pharmacological Actions : Cytoprotective, Neuroprotective Agents
[+]

Puerarin: A review of its mechanisms of action and clinical studies in ophthalmology.Nov 30, 2022

Pubmed Data : Phytomedicine. 2022 Dec ;107:154465. Epub 2022 Sep 19. PMID: 36166943
Article Published Date : Nov 30, 2022
Study Type : Review
Additional Links
Substances : Puerarin
Diseases : Diabetic Retinopathy, Eye Diseases, Glaucoma
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Bcl-2 protein down-regulation, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Protein Kinase Inhibitors, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Research progress of puerarin and its derivatives on anti-inflammatory and anti-gout activities.Sep 30, 2017

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2017 Oct ;42(19):3703-3708. PMID: 29235282
Article Published Date : Sep 30, 2017
Study Type : Review
Additional Links
Substances : Puerarin
Diseases : Gout
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Natural Substances Versus Drugs
[+]

Roles and mechanisms of puerarin on cardiovascular disease.Feb 28, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2022 Mar ;147:112655. Epub 2022 Jan 20. PMID: 35066299
Article Published Date : Feb 28, 2022
Study Type : Review
Additional Links
Substances : Puerarin
Diseases : Cardiovascular Diseases
Pharmacological Actions : Hypolipidemic
[+]

Study on the mechanism of puerarin against osteoarthritis from ferroptosis based on network pharmacology and bioinformatics.Aug 06, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2023 Aug 7. Epub 2023 Aug 7. PMID: 37548663
Article Published Date : Aug 06, 2023
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

The inhibitory effects of plant derivate polyphenols on the main protease of SARS coronavirus 2.Mar 29, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2021 Mar 30 ;26(7). Epub 2021 Mar 30. PMID: 33808054
Article Published Date : Mar 29, 2021
Study Type : In Vitro Study
Additional Links
Substances : Daidzein, Myricetin, Polyphenols, Puerarin, Tannic Acid
Diseases : Coronavirus Infection
Pharmacological Actions : Antiviral Agents
Additional Keywords : Drug Synergy, Plant Extracts
[+]

The isoflavone puerarin exerts anti-tumor activity in pancreatic ductal adenocarcinoma by suppressing mTOR-mediated glucose metabolism.Dec 03, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aging (Albany NY). 2021 Dec 4 ;13(23):25089-25105. Epub 2021 Dec 4. PMID: 34863080
Article Published Date : Dec 03, 2021
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Pancreatic Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
[+]

The role of puerarin in chronic wounds.Mar 10, 2022

Pubmed Data : Int J Low Extrem Wounds. 2022 Mar 11:15347346221086687. Epub 2022 Mar 11. PMID: 35274996
Article Published Date : Mar 10, 2022
Study Type : Review
Additional Links
Substances : Puerarin
Diseases : Wound Healing
Pharmacological Actions : Angiogenesis Modulating Agents, Anti-Inflammatory Agents, Antioxidants
[+]

These data suggested that puerarin inhibited LPS-induced iNOS, COX-2 and CRP expression.Dec 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacol Rep. 2011 ;63(3):781-9. PMID: 21857089
Article Published Date : Dec 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : C-Reactive Protein, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor
[+]

These findings indicate that puerarin may act as a chemopreventive and chemotherapeutic agent in colon cancer cells.Jul 07, 2006

Pubmed Data : Cancer Lett. 2006 Jul 8 ;238(1):53-60. Epub 2005 Aug 1. PMID: 16055262
Article Published Date : Jul 07, 2006
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Chemopreventive, Chemotherapeutic
[+]

These findings suggest that puerarin prevent Aβ-induced neurotoxicity through inhibiting neuronal apoptosis.May 29, 2011

Pubmed Data : Brain Res Bull. 2011 May 30 ;85(3-4):212-8. Epub 2011 Apr 5. PMID: 21473901
Article Published Date : May 29, 2011
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

These results showed that puerarin exerted protective effects against myocardial ischemia/reperfusion injury.Mar 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2023 Apr 1 ;46(4):524-532. Epub 2023 Jan 26. PMID: 36696989
Article Published Date : Mar 31, 2023
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Myocardial Ischemia
Pharmacological Actions : Cardioprotective
[+]

These results suggest that puerarin can protect neurons against oxidative stress.Dec 31, 2002

Pubmed Data : Cell Biol Int. 2003 ;27(12):1025-31. PMID: 14642535
Article Published Date : Dec 31, 2002
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Hydrogen Peroxide Induced Toxicity, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

This data contributes to a better understanding the mechanism of puerarin cardioprotection in the treatment of cardiovascular diseases.Oct 19, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2016 Oct 20 ;6:35475. Epub 2016 Oct 20. PMID: 27762288
Article Published Date : Oct 19, 2016
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Cardiovascular Diseases
Pharmacological Actions : Cardioprotective
Additional Keywords : Cardiovascular Diseases, Chinese herb medicine, Heart Disease, Puerarin
[+]

This present study revealed that puerarin might be a novel therapeutic drug for breast cancer treatment.Jul 31, 2017

Pubmed Data : Biomed Pharmacother. 2017 Aug ;92:429-436. Epub 2017 May 27. PMID: 28558356
Article Published Date : Jul 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Breast Cancer, Breast Cancer: Triple Negative , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-metastatic, Interleukin-6 Downregulation, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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