Pumpkin

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59 Diseases Researched for Pumpkin
NameACCKFocus
Prostatic Hyperplasia: Benign634Locked
Diabetes Mellitus: Type 2322Locked
Overactive Bladder220Locked
Hair Loss313Locked
Hyperglycemia212Locked
Anemia: Iron Deficiency110Locked
Anti-Social Behavior110Locked
Anxiety Disorders110Locked
Bladder Stones110Locked
C-Reactive Protein110Locked
Diabetes Mellitus: Type 1110Locked
HDL: Low110Locked
Hot Flash110Locked
Inflammation110Locked
Insomnia110Locked
Kidney Failure: Acute110Locked
Lung Cancer: Prevention110Locked
Phobia: Social110Locked
Postmenopausal Disorders110Locked
Triglycerides: Elevated110Locked
Oxidative Stress69Locked
Liver Cancer27Locked
Chemically-Induced Liver Damage24Locked
Erectile Dysfunction24Locked
Hypertension24Locked
Parasitic Intestinal Diseases24Locked
Prostatic Hyperplasia, Testosterone-Induced24Locked
Alopecia23Locked
Colon Cancer23Locked
Acetaminophen (Tylenol) Toxicity 12Locked
Alcohol Toxicity 12Locked
Arteriosclerosis12Locked
Arthritis12Locked
Athletic Performance12Locked
Bisphenol Toxicity12Locked
Chemotherapy-Induced Toxicity: Gentamicin12Locked
Colon Cancer: Prevention12Locked
Diabetic Nephropathy12Locked
Drug Toxicity: Methotrexate12Locked
Fatigue12Locked
Gastrointestinal Hemorrhage12Locked
Helminthiasis12Locked
High Cholesterol12Locked
Hyperlipidemia12Locked
Lipid Peroxidation12Locked
Neurotoxicity12Locked
Protein Malnourishment12Locked
Tapeworm Infection12Locked
Testicular Injury: Chemical/Metal Induced12Locked
Tuberculosis Drug Induced Toxicity 12Locked
Wound Healing12Locked
Breast Cancer11Locked
Chemotherapy-Induced Toxicity: Cisplatin11Locked
Hydrogen Peroxide Induced Toxicity11Locked
Lower Urinary Tract Symptoms11Locked
Obesity11Locked
Prostate Cancer11Locked
Schistosomiasis11Locked
Thyroid Cancer11Locked
29 Pharmacological Actions Researched for Pumpkin
NameACCKFocus
Hypoglycemic Agents525Locked
Antioxidants1322Locked
Anti-Inflammatory Agents313Locked
Antihypertensive Agents212Locked
Anticholesteremic Agents110Locked
Anxiolytic110Locked
Hepatoprotective510Locked
Hypolipidemic110Locked
Apoptotic38Locked
Malondialdehyde Down-regulation48Locked
Antiproliferative 37Locked
Bcl-2 protein down-regulation15Locked
Antiparasitic Agents23Locked
Chemoprotective Agents23Locked
Superoxide Dismutase Up-regulation23Locked
Antinoceceptive 12Locked
Cardioprotective12Locked
Catalase Up-Regulation12Locked
Chemopreventive12Locked
Ergogenic12Locked
Gastroprotective12Locked
Genoprotective12Locked
Neuroprotective Agents12Locked
Renoprotective12Locked
Anti-Androgen11Locked
Cytoprotective11Locked
Immunomodulatory11Locked
NF-kappaB Inhibitor11Locked
Nitric Oxide Inhibitor11Locked

View the Evidence:
67 Abstracts with Pumpkin Research

[+]

C. maxima may decrease high blood glucose level fast and effective in diabetic critically ill patients.May 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Pharm Bull. 2018 Jun ;8(2):347-351. Epub 2018 Jun 19. PMID: 30023337
Article Published Date : May 31, 2018
Study Type : Human Study
Additional Links
Substances : Pumpkin
Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2, Hyperglycemia
Pharmacological Actions : Hypoglycemic Agents
[+]

Consumption of C. ficifolia and probiotic yogurt may help treatment of diabetic patients.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Prev Med. 2016 ;7:30. Epub 2016 Feb 2. PMID: 26955460
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Pumpkin, Yoghurt
Diseases : C-Reactive Protein, Diabetes Mellitus: Type 2, Inflammation, Triglycerides: Elevated
Pharmacological Actions : Anti-Inflammatory Agents, Anticholesteremic Agents, Antihypertensive Agents, Hypoglycemic Agents, Hypolipidemic
[+]

consumption of specific green leafy vegetables and other vegetables might be associated with a reduced risk of lung cancer. Dec 31, 2013

Pubmed Data : Nutr Cancer. 2014 ;66(6):1030-7. Epub 2014 Aug 1. PMID: 25085257
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Substances : Broccoli, Green Leafy Vegetables, Pumpkin
Diseases : Lung Cancer: Prevention
Additional Keywords : Risk Reduction
[+]

Cucurbita pepo-Rhus aromatica-Humulus lupulus combination reduces overactive bladder symptoms in women.Jun 30, 2019

Pubmed Data : Planta Med. 2019 Jul 1. Epub 2019 Jul 1. PMID: 31261419
Article Published Date : Jun 30, 2019
Study Type : Human Study
Additional Links
Substances : Hops, Pumpkin
Diseases : Overactive Bladder
Additional Keywords : Plant Extracts
[+]

Findings of the present trial provide evidence of a promising potential role of pumpkin seed oil in treating female pattern hair loss.Feb 04, 2021

Pubmed Data : J Cosmet Dermatol. 2021 Feb 5. Epub 2021 Feb 5. PMID: 33544448
Article Published Date : Feb 04, 2021
Study Type : Human Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Hair Loss
[+]

Oral combination of pumpkin seed extract, soy germ isoflavonoids, and cranberry could be beneficial for benign prostate hyperplasia patients.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Urol. 2020 ;2020:6325490. Epub 2020 Jan 13. PMID: 32215007
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Substances : Cranberry, Pumpkin
Diseases : Prostatic Hyperplasia: Benign
[+]

Pumpkin seed consumption contributes to alleviating iron-deficiency associated anemia. Jul 01, 1995

Pubmed Data : AIDS Asia. 1995 Jul-Aug;2(4):6-7. PMID: 18198398
Article Published Date : Jul 01, 1995
Study Type : Human Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Anemia: Iron Deficiency
[+]

Pumpkin seed oil (prostafit) is effective and a safe alternative treatment in benign prostatic hyperplasia.May 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pak Med Assoc. 2014 Jun ;64(6):683-5. PMID: 25252490
Article Published Date : May 31, 2014
Study Type : Human Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Prostatic Hyperplasia: Benign
Additional Keywords : Phytotherapy, Plant Oils
[+]

Pumpkin seed oil and saw palmetto oil may be effective as complementary and alternative medicine treatments for benign prostatic hyperplasia.Dec 31, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res Pract. 2009 ;3(4):323-7. Epub 2009 Dec 31. PMID: 20098586
Article Published Date : Dec 31, 2008
Study Type : Human Study
Additional Links
Substances : Pumpkin, Saw Palmetto
Diseases : Prostatic Hyperplasia: Benign
[+]

Pumpkin seed oil extracted from C. maxima has the potential for prevention or treatment of urinary disorders.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Complement Med. 2014 Jan ;4(1):72-4. PMID: 24872936
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Overactive Bladder
[+]

Pumpkin seed oil has beneficial properties in postmenopausal women. May 05, 2011

Pubmed Data : Climacteric. 2011 May 5. Epub 2011 May 5. PMID: 21545273
Article Published Date : May 05, 2011
Study Type : Human Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : HDL: Low, Hot Flash, Postmenopausal Disorders
[+]

Pumpkin seeds reduce calcium-oxalate crystal occurence in the urine of children. Jan 01, 1987

Pubmed Data : Am J Clin Nutr. 1987 Jan;45(1):115-21. PMID: 3799495
Article Published Date : Jan 01, 1987
Study Type : Human Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Bladder Stones, Kidney Failure: Acute
[+]

Tryptophan-rich gourd seeds are a potential anxiolytic to those suffering from social phobia.Sep 01, 2007

Pubmed Data : Can J Physiol Pharmacol. 2007 Sep;85(9):928-32. PMID: 18066139
Article Published Date : Sep 01, 2007
Study Type : Human Study
Additional Links
Substances : Gourd, Pumpkin Seed Oil/Meal, Tryptophan
Diseases : Anti-Social Behavior, Anxiety Disorders, Phobia: Social
Pharmacological Actions : Anxiolytic
[+]

Tryptophan-rich gourd seeds significantly improve subjective and objective measurements of insomnia.Apr 01, 2005

Pubmed Data : Nutr Neurosci. 2005 Apr;8(2):121-7. PMID: 16053244
Article Published Date : Apr 01, 2005
Study Type : Human Study
Additional Links
Substances : Gourd, Pumpkin Seed Oil/Meal, Tryptophan
Diseases : Insomnia
[+]

Cucurmosin has potential anticancer activity for human hepatoma.Dec 31, 2011

Pubmed Data : Mol Med Rep. 2012 Jan ;5(1):196-201. Epub 2011 Sep 30. PMID: 21964700
Article Published Date : Dec 31, 2011
Study Type : Human In Vitro
Additional Links
Substances : Pumpkin
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation
[+]

Pumpkin seed oil-loaded niosomes for topical application: 5α-reductase inhibitory, anti-inflammatory, and in vivo anti-hair loss effects.Jul 26, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2022 Jul 27 ;15(8). Epub 2022 Jul 27. PMID: 36015077
Article Published Date : Jul 26, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Hair Loss
Pharmacological Actions : 5-alpha reductase inhibitor, Anti-Inflammatory Agents
[+]

A flax and pumpkin seed mixture has anti-atherogenic and hepatoprotective effects. Dec 01, 2008

Pubmed Data : Food Chem Toxicol. 2008 Dec;46(12):3714-20. Epub 2008 Oct 1. PMID: 18938206
Article Published Date : Dec 01, 2008
Study Type : Animal Study
Additional Links
Substances : Flaxseed, Omega-3 Fatty Acids, Pumpkin Seed Oil/Meal
Diseases : Arteriosclerosis, High Cholesterol
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

A purified polysaccharide from pumpkin fruit directly induces apoptotic cell death of HepG2 cells.Jun 16, 2017

Pubmed Data : Int J Biol Macromol. 2017 Jun 17 ;104(Pt A):681-686. Epub 2017 Jun 17. PMID: 28634059
Article Published Date : Jun 16, 2017
Study Type : Animal Study
Additional Links
Substances : Pumpkin
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic
[+]

Accelerating effect of Cucurbita pepo L. fruit extract on excisional wound healing.Aug 14, 2022

Pubmed Data : Nutrients. 2022 Aug 15 ;14(16). Epub 2022 Aug 15. PMID: 36014842
Article Published Date : Aug 14, 2022
Study Type : Animal Study
Additional Links
Substances : Pumpkin
Diseases : Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Plant Extracts
[+]

Animal's studies showed that oxidized oils decreased the whole body weight, which was ameliorated by the co-administration of un-oxidized oils. Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Chem. 2017 ;5:55. Epub 2017 Jul 26. PMID: 28798910
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
[+]

Antinociceptive and antioxidant activities of the methanolic extract of Telfairia occidentalis seeds.Sep 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anc Sci Life. 2016 Oct-Dec;36(2):98-103. PMID: 28446831
Article Published Date : Sep 30, 2016
Study Type : Animal Study
Additional Links
Substances : Pumpkin
Diseases : Oxidative Stress
Pharmacological Actions : Antinoceceptive , Antioxidants
[+]

Beneficial effects of pumpkin seed oil as a topical hair growth promoting agent in a mice model.Oct 31, 2019

Pubmed Data : Avicenna J Phytomed. 2019 Nov-Dec;9(6):499-504. PMID: 31763209
Article Published Date : Oct 31, 2019
Study Type : Animal Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Alopecia, Hair Loss
Additional Keywords : Hair Regeneration
[+]

C. pepo might ameliorate the progression of diabetic neuropathy.Jul 31, 2023

Pubmed Data : Environ Sci Pollut Res Int. 2023 Aug ;30(36):85910-85919. Epub 2023 Jul 3. PMID: 37400700
Article Published Date : Jul 31, 2023
Study Type : Animal Study
Additional Links
Substances : Pumpkin
Diseases : Diabetic Neuropathy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Renoprotective, Transforming growth factor beta (TGF-β) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Cucumis sativus and Cucurbita maxima extract attenuate diabetes-induced hepatic and pancreatic injury in a rat model.Jul 31, 2020

Pubmed Data : J Physiol Pharmacol. 2020 Aug ;71(4). Epub 2020 Nov 15. PMID: 33214339
Article Published Date : Jul 31, 2020
Study Type : Animal Study
Additional Links
Substances : Cucumber, Pumpkin
Diseases : Diabetic Complications
Pharmacological Actions : Antioxidants, Hypoglycemic Agents
Additional Keywords : Drug Synergy, Plant Extracts
[+]

Diets supplemented with raw and roasted pumpkin seeds improved some biochemical parameters associated with erectile function.Jan 31, 2021

Pubmed Data : J Food Biochem. 2021 Feb ;45(2):e13629. Epub 2021 Jan 27. PMID: 33502019
Article Published Date : Jan 31, 2021
Study Type : Animal Study
Additional Links
Substances : Pumpkin
Diseases : Erectile Dysfunction
Pharmacological Actions : Antioxidants
[+]

Ellagic acid and pumpkin seed oil protects against methotrexate-induced small intestine damage in rats.Nov 30, 2011

Pubmed Data : Indian J Biochem Biophys. 2011 Dec ;48(6):380-7. PMID: 22329239
Article Published Date : Nov 30, 2011
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid, Pumpkin Seed Oil/Meal
Diseases : Drug Toxicity: Methotrexate, Gastrointestinal Hemorrhage
Pharmacological Actions : Gastroprotective
[+]

Flax and Pumpkin seeds mixture supplemented in diet of diabetic rats may be helpful to prevent diabetes and its complications.Jul 31, 2010

Pubmed Data : Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2407-12. Epub 2010 Jun 4. PMID: 20570704
Article Published Date : Jul 31, 2010
Study Type : Animal Study
Additional Links
Substances : Flaxseed, Pumpkin
Diseases : Diabetic Nephropathy
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
Additional Keywords : Phytotherapy
[+]

Fluted pumpkin leaf extracts have hepatoprotective properties.Dec 31, 2004

Pubmed Data : J Med Food. 2005 ;8(4):560-3. PMID: 16379574
Article Published Date : Dec 31, 2004
Study Type : Animal Study
Additional Links
Substances : Pumpkin
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Hepatoprotective
Additional Keywords : Plant Extracts
[+]

In silico study of Cucurbita maxima compounds as potential therapeutics against schistosomiasis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Bioinform Biol Insights. 2022 ;16:11779322221100741. Epub 2022 May 20. PMID: 35615403
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Pumpkin
Diseases : Schistosomiasis
Pharmacological Actions : Antiparasitic Agents
[+]

Pumpkin (Cucurbita moschata) Fruit Extract Improves Physical Fatigue and Exercise Performance in Mice.Dec 31, 2011

Pubmed Data : Molecules. 2012 ;17(10):11864-76. Epub 2012 Oct 9. PMID: 23047485
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Pumpkin
Diseases : Athletic Performance, Fatigue
Pharmacological Actions : Ergogenic
[+]

Pumpkin fruit peel has a protective effect against carbon tetrachloride induced neurotoxicity.Oct 31, 2014

Pubmed Data : Pak J Pharm Sci. 2014 Nov ;27(6):1967-73. PMID: 25362619
Article Published Date : Oct 31, 2014
Study Type : Animal Study
Additional Links
Substances : Pumpkin
Diseases : Lipid Peroxidation, Neurotoxicity
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents
Additional Keywords : Dose Response, Plant Extracts
Adverse Pharmacological Actions : Neurotoxic
[+]

Pumpkin Seed contributes to inhibiting prostate growth. - Article 2Mar 01, 2008

Pubmed Data : QJM. 2008 Mar;101(3):167-79. Epub 2008 Jan 25. PMID: 16822218
Article Published Date : Mar 01, 2008
Study Type : Animal Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Prostatic Hyperplasia, Testosterone-Induced
[+]

Pumpkin seed is effective in controlling gastrointestinal helminths in naturally infected ostriches.Jun 08, 2012

Pubmed Data : Trop Anim Health Prod. 2012 Jun 9. Epub 2012 Jun 9. PMID: 22684690
Article Published Date : Jun 08, 2012
Study Type : Animal Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Helminthiasis, Parasitic Intestinal Diseases
Pharmacological Actions : Antiparasitic Agents
[+]

Pumpkin seed may prevent the risk of colon cancer when consumed in dietary proportions.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Toxicol. 2018 ;2018:6086490. Epub 2018 Sep 2. PMID: 30245714
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Colon Cancer, Colon Cancer: Prevention
Pharmacological Actions : Chemopreventive
Additional Keywords : Dietary Modification
[+]

Pumpkin seed oil can block testosterone induced increases in prostate size and protein synthesis. Jan 01, 2006

Pubmed Data : Urol Int. 2006;77(3):269-74. PMID: 17033217
Article Published Date : Jan 01, 2006
Study Type : Animal Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Prostatic Hyperplasia, Testosterone-Induced, Prostatic Hyperplasia: Benign
[+]

Pumpkin seed oil contributes to the beneficial effect of an ACE-inhibitor and Calcium-Channel Blocker in the treatment of hypertension. May 01, 2000

Pubmed Data : Pharmacol Res. 2000 May;41(5):555-63. PMID: 10753555
Article Published Date : May 01, 2000
Study Type : Animal Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Hypertension
[+]

Pumpkin seed oil exhibits an antihypertensive and cardioprotective effects.Jan 31, 2012

Pubmed Data : J Med Food. 2012 Feb ;15(2):180-9. Epub 2011 Nov 14. PMID: 22082068
Article Published Date : Jan 31, 2012
Study Type : Animal Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents, Cardioprotective, Malondialdehyde Down-regulation
[+]

Pumpkin seed oil improves lipid profile and cardiovascular outcomes in female rats. Jul 01, 2008

Pubmed Data : Phytother Res. 2008 Jul;22(7):873-7. PMID: 18567058
Article Published Date : Jul 01, 2008
Study Type : Animal Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Hyperlipidemia
[+]

Pumpkin seed oil may have a protective role against BPA genotoxicity and histopathological alterations in male mice.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Rep. 2018 ;5:857-863. Epub 2018 Aug 17. PMID: 30167376
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Bisphenol Toxicity
Pharmacological Actions : Genoprotective
Problem Substances : Bisphenol A
[+]

Pumpkin seed oil reduces the symptoms of arthritis as effectively as indomethacin, without causing liver damage. Jan 01, 1995

Pubmed Data : Pharmacol Res. 1995 Jan;31(1):73-9. PMID: 7784309
Article Published Date : Jan 01, 1995
Study Type : Animal Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Arthritis
Additional Keywords : Natural Substances Versus Drugs
[+]

Pumpkin seed protein isolate administration is effective in alleviating the detrimental effects associated with protein malnutrition and acetaminophen intoxication.Aug 31, 2006

Pubmed Data : Phytother Res. 2006 Sep ;20(9):780-3. PMID: 16807884
Article Published Date : Aug 31, 2006
Study Type : Animal Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Acetaminophen (Tylenol) Toxicity , Protein Malnourishment
Pharmacological Actions : Antioxidants, Hepatoprotective
Additional Keywords : Plant Extracts
[+]

Pumpkin seed protein isolate has significant antioxidant activity. May 01, 2009

Pubmed Data : Arch Biochem Biophys. 2009 May 1;485(1):63-71. Epub 2009 Feb 20. PMID: 16909447
Article Published Date : May 01, 2009
Study Type : Animal Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Oxidative Stress
[+]

Pumpkin seed protein isolate protects against CCl4-induced liver injury in low-protein fed rats.Mar 31, 2005

Pubmed Data : Phytother Res. 2005 Apr ;19(4):341-5. PMID: 16041732
Article Published Date : Mar 31, 2005
Study Type : Animal Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Hepatoprotective
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Pumpkin seeds has an antiparasitic effect against canine tapeworms. Oct 01, 2004

Pubmed Data : Rev Gastroenterol Peru. 2004 Oct-Dec;24(4):323-7. PMID: 15614300
Article Published Date : Oct 01, 2004
Study Type : Animal Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Parasitic Intestinal Diseases, Tapeworm Infection
[+]

T. occidentalis attenuated the deleterious effects of alcohol to the cyto-architecture of the testis.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Rep. 2015 ;2:968-975. Epub 2015 Jun 18. PMID: 28962436
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Pumpkin
Diseases : Alcohol Toxicity , Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation
[+]

Telfairia occidentalis pulp extract mitigates rifampicin-isoniazid-induced hepatotoxicity.Dec 31, 2018

Pubmed Data : J Integr Med. 2019 Jan ;17(1):46-56. Epub 2018 Dec 1. PMID: 30555014
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Pumpkin
Diseases : Chemically-Induced Liver Damage, Tuberculosis Drug Induced Toxicity
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

The administration of the extract together with and after the administration of gentamycin reverses renal damage caused by gentamycin.Dec 31, 2016

Pubmed Data : J Basic Clin Physiol Pharmacol. 2017 Jan 1 ;28(1):11-17. PMID: 27658143
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Pumpkin
Diseases : Chemotherapy-Induced Toxicity: Gentamicin
Pharmacological Actions : Chemoprotective Agents, Renoprotective
Additional Keywords : Plant Extracts
[+]

The combined administration of pumpkin polysaccharides and puerarin could synergistically ameliorate T2DM.Mar 07, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Mar 8 ;24(5). Epub 2019 Mar 8. PMID: 30857163
Article Published Date : Mar 07, 2019
Study Type : Animal Study
Additional Links
Substances : Puerarin, Pumpkin
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Natural Substance Synergy, Polysaccharides
[+]

The present study provides valuable evidence on the possible health benefits of Mayan plant foods.Jan 07, 2021

Pubmed Data : J Sci Food Agric. 2021 Jan 8. Epub 2021 Jan 8. PMID: 33420740
Article Published Date : Jan 07, 2021
Study Type : Animal Study
Additional Links
Substances : Achiote, Guava, Pumpkin, Radish
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
[+]

The results suggest that Telfairia occidentalis-induced lowering of plasma glucose afterone week of treatment.Dec 29, 2018

Pubmed Data : Niger J Physiol Sci. 2018 Dec 30 ;33(2):169-175. Epub 2018 Dec 30. PMID: 30837771
Article Published Date : Dec 29, 2018
Study Type : Animal Study
Additional Links
Substances : Pumpkin
Diseases : Hyperglycemia
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Plant Extracts
[+]

This study brought to limelight the medicinal importance of fluted pumpkin seed in erectile functions.Sep 08, 2019

Pubmed Data : J Food Biochem. 2019 Sep 9:e13037. Epub 2019 Sep 9. PMID: 31502274
Article Published Date : Sep 08, 2019
Study Type : Animal Study
Additional Links
Substances : Pumpkin
Diseases : Erectile Dysfunction
[+]

This study showed the significance of oil from pumpkin seeds as a promising drug to healing wounds in animal assays.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lipids Health Dis. 2016 ;15(1):73. Epub 2016 Apr 11. PMID: 27068642
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Pumpkin
Diseases : Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Oils
[+]

A review of herbal preparations for the treatment of hair loss.Nov 02, 2019

Pubmed Data : Arch Dermatol Res. 2019 Nov 3. Epub 2019 Nov 3. PMID: 31680216
Article Published Date : Nov 02, 2019
Study Type : Review
Additional Links
Substances : Ginger, Ginseng, Ginseng (Korean), Pumpkin, Red Clover, Saw Palmetto
Diseases : Alopecia, Hair Loss
[+]

Anti-proliferative and apoptotic effects of hull-less pumpkin extract on human papillary thyroid carcinoma cell line.Jan 27, 2021

Pubmed Data : Anat Cell Biol. 2021 Jan 28. Epub 2021 Jan 28. PMID: 33504684
Article Published Date : Jan 27, 2021
Study Type : In Vitro Study
Additional Links
Substances : Pumpkin
Diseases : Thyroid Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Antioxidants and health-beneficial nutrients in fruits of eighteen Cucurbita cultivars.Apr 13, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Apr 14 ;25(8). Epub 2020 Apr 14. PMID: 32295156
Article Published Date : Apr 13, 2020
Study Type : In Vitro Study
Additional Links
Substances : Pumpkin
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Effect of dietary inclusion of pumpkin seed on nephrotoxicity occasioned by cisplatin in experimental rats.Aug 17, 2020

Pubmed Data : J Food Biochem. 2020 Aug 18:e13439. Epub 2020 Aug 18. PMID: 32808341
Article Published Date : Aug 17, 2020
Study Type : In Vitro Study
Additional Links
Substances : Pumpkin
Diseases : Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Chemoprotective Agents
[+]

Effect of roasting on the antioxidant activity, phenolic composition, and nutritional quality of pumpkin seeds.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2021 ;8:647354. Epub 2021 Mar 10. PMID: 33777995
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Pumpkin
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

In vitro role of pumpkin parts as pharma-Foods: antihyperglycemic and antihyperlipidemic activities.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Food Sci. 2022 ;2022:4804408. Epub 2022 Aug 2. PMID: 35959224
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Pumpkin
Diseases : Hyperglycemia, Hyperlipidemia
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
[+]

Phytochemical analysis and antioxidant activity of the seed of Telfairia occidentalis.Jan 31, 2018

Pubmed Data : Nat Prod Res. 2018 Feb ;32(4):444-447. Epub 2017 Mar 31. PMID: 28361553
Article Published Date : Jan 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Pumpkin
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Polysaccharides from pumpkin have antioxidant and cytoprotective effects. Oct 14, 2013

Pubmed Data : Carbohydr Polym. 2013 Oct 15 ;98(1):686-91. Epub 2013 Jun 29. PMID: 23987399
Article Published Date : Oct 14, 2013
Study Type : In Vitro Study
Additional Links
Substances : Pumpkin
Diseases : Hydrogen Peroxide Induced Toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants, Cytoprotective
Additional Keywords : Polysaccharides
[+]

Pumpkin (Cucurbita ficifolia Bouché) extract attenuate the adipogenesis in human mesenchymal stem cells by controlling adipogenic gene expression.Apr 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi J Biol Sci. 2019 May ;26(4):744-751. Epub 2018 Oct 2. PMID: 31048999
Article Published Date : Apr 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Pumpkin
Diseases : Obesity
Additional Keywords : Anti-Obesity Agents, Gene Expression Regulation
[+]

Pumpkin polysaccharides: Purification, characterization and hypoglycemic potential.Aug 06, 2019

Pubmed Data : Int J Biol Macromol. 2019 Aug 7 ;139:842-849. Epub 2019 Aug 7. PMID: 31400422
Article Published Date : Aug 06, 2019
Study Type : In Vitro Study
Additional Links
Substances : Pumpkin
Pharmacological Actions : Antioxidants, Hypoglycemic Agents, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
Additional Keywords : Polysaccharides
[+]

Pumpkin seed extract had growth inhibition effects on hyperplastic and some cancer cell lines. Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Fitoterapia. 2016 Apr ;110:150-6. Epub 2016 Mar 11. PMID: 26976217
Article Published Date : Mar 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Pumpkin, Pumpkin Seeds
Diseases : Breast Cancer, Colon Cancer, Prostate Cancer, Prostatic Hyperplasia: Benign
Pharmacological Actions : Antiproliferative
Additional Keywords : Plant Extracts
[+]

Pumpkin seed oil: A comprehensive review of extraction methods, nutritional constituents and health benefits.Aug 30, 2023

Pubmed Data : J Sci Food Agric. 2023 Aug 31. Epub 2023 Aug 31. PMID: 37650308
Article Published Date : Aug 30, 2023
Study Type : Review
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Cancers: All, Cardiovascular Diseases, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective
[+]

Pumpkin-seed oil possesses effective antischistosomal activity against various stages of S. mansoni.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Infect Drug Resist. 2020 ;13:3469-3484. Epub 2020 Oct 7. PMID: 33116667
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Schistosomiasis
Pharmacological Actions : Antiparasitic Agents
[+]

The use of pumpkin seed could be beneficial in the treatment of lower urinary tract symptoms related to benign prostatic hyperplasia.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Ital Urol Androl. 2016 ;88(2):136-43. Epub 2016 Jul 4. PMID: 27377091
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Pumpkin
Diseases : Lower Urinary Tract Symptoms, Prostatic Hyperplasia: Benign
Pharmacological Actions : Anti-Androgen, Anti-Inflammatory Agents
[+]

These results suggest that the pumpkin extracts may have immunomodulatory effects.Sep 30, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Res Pharm Sci. 2012 Oct ;7(4):217-24. PMID: 23248672
Article Published Date : Sep 30, 2012
Study Type : In Vitro Study
Additional Links
Substances : Pumpkin
Pharmacological Actions : Immunomodulatory
Additional Keywords : Dose Response, Plant Extracts

Copyright: alexraths / 123RF Stock Photo

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