Pumpkin

Name	AC	CK
Prostatic Hyperplasia: Benign	6	34
Diabetes Mellitus: Type 2	3	22
Overactive Bladder	2	20
Hair Loss	3	13
Hyperglycemia	2	12
Anemia: Iron Deficiency	1	10
Anti-Social Behavior	1	10
Anxiety Disorders	1	10
Bladder Stones	1	10
C-Reactive Protein	1	10
Diabetes Mellitus: Type 1	1	10
HDL: Low	1	10
Hot Flash	1	10
Inflammation	1	10
Insomnia	1	10
Kidney Failure: Acute	1	10
Lung Cancer: Prevention	1	10
Phobia: Social	1	10
Postmenopausal Disorders	1	10
Triglycerides: Elevated	1	10
Oxidative Stress	6	9
Liver Cancer	2	7
Chemically-Induced Liver Damage	2	4
Erectile Dysfunction	2	4
Hypertension	2	4
Parasitic Intestinal Diseases	2	4
Prostatic Hyperplasia, Testosterone-Induced	2	4
Alopecia	2	3
Colon Cancer	2	3
Acetaminophen (Tylenol) Toxicity	1	2
Alcohol Toxicity	1	2
Arteriosclerosis	1	2
Arthritis	1	2
Athletic Performance	1	2
Bisphenol Toxicity	1	2
Chemotherapy-Induced Toxicity: Gentamicin	1	2
Colon Cancer: Prevention	1	2
Diabetic Nephropathy	1	2
Drug Toxicity: Methotrexate	1	2
Fatigue	1	2
Gastrointestinal Hemorrhage	1	2
Helminthiasis	1	2
High Cholesterol	1	2
Hyperlipidemia	1	2
Lipid Peroxidation	1	2
Neurotoxicity	1	2
Protein Malnourishment	1	2
Tapeworm Infection	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Tuberculosis Drug Induced Toxicity	1	2
Wound Healing	1	2
Breast Cancer	1	1
Chemotherapy-Induced Toxicity: Cisplatin	1	1
Hydrogen Peroxide Induced Toxicity	1	1
Lower Urinary Tract Symptoms	1	1
Obesity	1	1
Prostate Cancer	1	1
Schistosomiasis	1	1
Thyroid Cancer	1	1

Name	AC	CK
Hypoglycemic Agents	5	25
Antioxidants	13	22
Anti-Inflammatory Agents	3	13
Antihypertensive Agents	2	12
Anticholesteremic Agents	1	10
Anxiolytic	1	10
Hepatoprotective	5	10
Hypolipidemic	1	10
Apoptotic	3	8
Malondialdehyde Down-regulation	4	8
Antiproliferative	3	7
Bcl-2 protein down-regulation	1	5
Antiparasitic Agents	2	3
Chemoprotective Agents	2	3
Superoxide Dismutase Up-regulation	2	3
Antinoceceptive	1	2
Cardioprotective	1	2
Catalase Up-Regulation	1	2
Chemopreventive	1	2
Ergogenic	1	2
Gastroprotective	1	2
Genoprotective	1	2
Neuroprotective Agents	1	2
Renoprotective	1	2
Anti-Androgen	1	1
Cytoprotective	1	1
Immunomodulatory	1	1
NF-kappaB Inhibitor	1	1
Nitric Oxide Inhibitor	1	1

[+]

C. maxima may decrease high blood glucose level fast and effective in diabetic critically ill patients.May 31, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Adv Pharm Bull. 2018 Jun ;8(2):347-351. Epub 2018 Jun 19. PMID: 30023337

Article Published Date : May 31, 2018

Study Type : Human Study

Additional Links

Substances : Pumpkin

Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2, Hyperglycemia

Pharmacological Actions : Hypoglycemic Agents

[+]

Consumption of C. ficifolia and probiotic yogurt may help treatment of diabetic patients.Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Prev Med. 2016 ;7:30. Epub 2016 Feb 2. PMID: 26955460

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Pumpkin, Yoghurt

Diseases : C-Reactive Protein, Diabetes Mellitus: Type 2, Inflammation, Triglycerides: Elevated

Pharmacological Actions : Anti-Inflammatory Agents, Anticholesteremic Agents, Antihypertensive Agents, Hypoglycemic Agents, Hypolipidemic

[+]

consumption of specific green leafy vegetables and other vegetables might be associated with a reduced risk of lung cancer. Dec 31, 2013

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Pubmed Data : Nutr Cancer. 2014 ;66(6):1030-7. Epub 2014 Aug 1. PMID: 25085257

Article Published Date : Dec 31, 2013

Study Type : Human Study

Additional Links

Substances : Broccoli, Green Leafy Vegetables, Pumpkin

Diseases : Lung Cancer: Prevention

Additional Keywords : Risk Reduction

[+]

Cucurbita pepo-Rhus aromatica-Humulus lupulus combination reduces overactive bladder symptoms in women.Jun 30, 2019

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Pubmed Data : Planta Med. 2019 Jul 1. Epub 2019 Jul 1. PMID: 31261419

Article Published Date : Jun 30, 2019

Study Type : Human Study

Additional Links

Substances : Hops, Pumpkin

Diseases : Overactive Bladder

Additional Keywords : Plant Extracts

[+]

Findings of the present trial provide evidence of a promising potential role of pumpkin seed oil in treating female pattern hair loss.Feb 04, 2021

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Pubmed Data : J Cosmet Dermatol. 2021 Feb 5. Epub 2021 Feb 5. PMID: 33544448

Article Published Date : Feb 04, 2021

Study Type : Human Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Hair Loss

[+]

Oral combination of pumpkin seed extract, soy germ isoflavonoids, and cranberry could be beneficial for benign prostate hyperplasia patients.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Adv Urol. 2020 ;2020:6325490. Epub 2020 Jan 13. PMID: 32215007

Article Published Date : Dec 31, 2019

Study Type : Human Study

Additional Links

Substances : Cranberry, Pumpkin

Diseases : Prostatic Hyperplasia: Benign

[+]

Pumpkin seed consumption contributes to alleviating iron-deficiency associated anemia. Jul 01, 1995

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Pubmed Data : AIDS Asia. 1995 Jul-Aug;2(4):6-7. PMID: 18198398

Article Published Date : Jul 01, 1995

Study Type : Human Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Anemia: Iron Deficiency

[+]

Pumpkin seed oil (prostafit) is effective and a safe alternative treatment in benign prostatic hyperplasia.May 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Pak Med Assoc. 2014 Jun ;64(6):683-5. PMID: 25252490

Article Published Date : May 31, 2014

Study Type : Human Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Prostatic Hyperplasia: Benign

Additional Keywords : Phytotherapy, Plant Oils

[+]

Pumpkin seed oil and saw palmetto oil may be effective as complementary and alternative medicine treatments for benign prostatic hyperplasia.Dec 31, 2008

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutr Res Pract. 2009 ;3(4):323-7. Epub 2009 Dec 31. PMID: 20098586

Article Published Date : Dec 31, 2008

Study Type : Human Study

Additional Links

Substances : Pumpkin, Saw Palmetto

Diseases : Prostatic Hyperplasia: Benign

[+]

Pumpkin seed oil extracted from C. maxima has the potential for prevention or treatment of urinary disorders.Dec 31, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Tradit Complement Med. 2014 Jan ;4(1):72-4. PMID: 24872936

Article Published Date : Dec 31, 2013

Study Type : Human Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Overactive Bladder

[+]

Pumpkin seed oil has beneficial properties in postmenopausal women. May 05, 2011

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Pubmed Data : Climacteric. 2011 May 5. Epub 2011 May 5. PMID: 21545273

Article Published Date : May 05, 2011

Study Type : Human Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : HDL: Low, Hot Flash, Postmenopausal Disorders

[+]

Pumpkin seeds reduce calcium-oxalate crystal occurence in the urine of children. Jan 01, 1987

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Pubmed Data : Am J Clin Nutr. 1987 Jan;45(1):115-21. PMID: 3799495

Article Published Date : Jan 01, 1987

Study Type : Human Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Bladder Stones, Kidney Failure: Acute

[+]

Tryptophan-rich gourd seeds are a potential anxiolytic to those suffering from social phobia.Sep 01, 2007

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Pubmed Data : Can J Physiol Pharmacol. 2007 Sep;85(9):928-32. PMID: 18066139

Article Published Date : Sep 01, 2007

Study Type : Human Study

Additional Links

Substances : Gourd, Pumpkin Seed Oil/Meal, Tryptophan

Diseases : Anti-Social Behavior, Anxiety Disorders, Phobia: Social

Pharmacological Actions : Anxiolytic

[+]

Tryptophan-rich gourd seeds significantly improve subjective and objective measurements of insomnia.Apr 01, 2005

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Pubmed Data : Nutr Neurosci. 2005 Apr;8(2):121-7. PMID: 16053244

Article Published Date : Apr 01, 2005

Study Type : Human Study

Additional Links

Substances : Gourd, Pumpkin Seed Oil/Meal, Tryptophan

Diseases : Insomnia

[+]

Cucurmosin has potential anticancer activity for human hepatoma.Dec 31, 2011

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Pubmed Data : Mol Med Rep. 2012 Jan ;5(1):196-201. Epub 2011 Sep 30. PMID: 21964700

Article Published Date : Dec 31, 2011

Study Type : Human In Vitro

Additional Links

Substances : Pumpkin

Diseases : Liver Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation

[+]

Pumpkin seed oil-loaded niosomes for topical application: 5α-reductase inhibitory, anti-inflammatory, and in vivo anti-hair loss effects.Jul 26, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Pharmaceuticals (Basel). 2022 Jul 27 ;15(8). Epub 2022 Jul 27. PMID: 36015077

Article Published Date : Jul 26, 2022

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Hair Loss

Pharmacological Actions : 5-alpha reductase inhibitor, Anti-Inflammatory Agents

[+]

A flax and pumpkin seed mixture has anti-atherogenic and hepatoprotective effects. Dec 01, 2008

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Pubmed Data : Food Chem Toxicol. 2008 Dec;46(12):3714-20. Epub 2008 Oct 1. PMID: 18938206

Article Published Date : Dec 01, 2008

Study Type : Animal Study

Additional Links

Substances : Flaxseed, Omega-3 Fatty Acids, Pumpkin Seed Oil/Meal

Diseases : Arteriosclerosis, High Cholesterol

Pharmacological Actions : Antioxidants, Hepatoprotective

[+]

A purified polysaccharide from pumpkin fruit directly induces apoptotic cell death of HepG2 cells.Jun 16, 2017

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Pubmed Data : Int J Biol Macromol. 2017 Jun 17 ;104(Pt A):681-686. Epub 2017 Jun 17. PMID: 28634059

Article Published Date : Jun 16, 2017

Study Type : Animal Study

Additional Links

Substances : Pumpkin

Diseases : Liver Cancer

Pharmacological Actions : Apoptotic

[+]

Accelerating effect of Cucurbita pepo L. fruit extract on excisional wound healing.Aug 14, 2022

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Pubmed Data : Nutrients. 2022 Aug 15 ;14(16). Epub 2022 Aug 15. PMID: 36014842

Article Published Date : Aug 14, 2022

Study Type : Animal Study

Additional Links

Substances : Pumpkin

Diseases : Wound Healing

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Additional Keywords : Plant Extracts

[+]

Animal's studies showed that oxidized oils decreased the whole body weight, which was ameliorated by the co-administration of un-oxidized oils. Dec 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Chem. 2017 ;5:55. Epub 2017 Jul 26. PMID: 28798910

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

[+]

Antinociceptive and antioxidant activities of the methanolic extract of Telfairia occidentalis seeds.Sep 30, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Anc Sci Life. 2016 Oct-Dec;36(2):98-103. PMID: 28446831

Article Published Date : Sep 30, 2016

Study Type : Animal Study

Additional Links

Substances : Pumpkin

Diseases : Oxidative Stress

Pharmacological Actions : Antinoceceptive , Antioxidants

[+]

Beneficial effects of pumpkin seed oil as a topical hair growth promoting agent in a mice model.Oct 31, 2019

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Pubmed Data : Avicenna J Phytomed. 2019 Nov-Dec;9(6):499-504. PMID: 31763209

Article Published Date : Oct 31, 2019

Study Type : Animal Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Alopecia, Hair Loss

Additional Keywords : Hair Regeneration

[+]

Cucumis sativus and Cucurbita maxima extract attenuate diabetes-induced hepatic and pancreatic injury in a rat model.Jul 31, 2020

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Pubmed Data : J Physiol Pharmacol. 2020 Aug ;71(4). Epub 2020 Nov 15. PMID: 33214339

Article Published Date : Jul 31, 2020

Study Type : Animal Study

Additional Links

Substances : Cucumber, Pumpkin

Diseases : Diabetic Complications

Pharmacological Actions : Antioxidants, Hypoglycemic Agents

Additional Keywords : Drug Synergy, Plant Extracts

[+]

Diets supplemented with raw and roasted pumpkin seeds improved some biochemical parameters associated with erectile function.Jan 31, 2021

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Pubmed Data : J Food Biochem. 2021 Feb ;45(2):e13629. Epub 2021 Jan 27. PMID: 33502019

Article Published Date : Jan 31, 2021

Study Type : Animal Study

Additional Links

Substances : Pumpkin

Diseases : Erectile Dysfunction

Pharmacological Actions : Antioxidants

[+]

Ellagic acid and pumpkin seed oil protects against methotrexate-induced small intestine damage in rats.Nov 30, 2011

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Pubmed Data : Indian J Biochem Biophys. 2011 Dec ;48(6):380-7. PMID: 22329239

Article Published Date : Nov 30, 2011

Study Type : Animal Study

Additional Links

Substances : Ellagic Acid, Pumpkin Seed Oil/Meal

Diseases : Drug Toxicity: Methotrexate, Gastrointestinal Hemorrhage

Pharmacological Actions : Gastroprotective

[+]

Flax and Pumpkin seeds mixture supplemented in diet of diabetic rats may be helpful to prevent diabetes and its complications.Jul 31, 2010

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Pubmed Data : Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2407-12. Epub 2010 Jun 4. PMID: 20570704

Article Published Date : Jul 31, 2010

Study Type : Animal Study

Additional Links

Substances : Flaxseed, Pumpkin

Diseases : Diabetic Nephropathy

Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation

Additional Keywords : Phytotherapy

[+]

Fluted pumpkin leaf extracts have hepatoprotective properties.Dec 31, 2004

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Pubmed Data : J Med Food. 2005 ;8(4):560-3. PMID: 16379574

Article Published Date : Dec 31, 2004

Study Type : Animal Study

Additional Links

Substances : Pumpkin

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants, Hepatoprotective

Additional Keywords : Plant Extracts

[+]

Pumpkin (Cucurbita moschata) Fruit Extract Improves Physical Fatigue and Exercise Performance in Mice.Dec 31, 2011

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Pubmed Data : Molecules. 2012 ;17(10):11864-76. Epub 2012 Oct 9. PMID: 23047485

Article Published Date : Dec 31, 2011

Study Type : Animal Study

Additional Links

Substances : Pumpkin

Diseases : Athletic Performance, Fatigue

Pharmacological Actions : Ergogenic

[+]

Pumpkin fruit peel has a protective effect against carbon tetrachloride induced neurotoxicity.Oct 31, 2014

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Pubmed Data : Pak J Pharm Sci. 2014 Nov ;27(6):1967-73. PMID: 25362619

Article Published Date : Oct 31, 2014

Study Type : Animal Study

Additional Links

Substances : Pumpkin

Diseases : Lipid Peroxidation, Neurotoxicity

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents

Additional Keywords : Dose Response, Plant Extracts

Adverse Pharmacological Actions : Neurotoxic

[+]

Pumpkin Seed contributes to inhibiting prostate growth. - Article 2Mar 01, 2008

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Pubmed Data : QJM. 2008 Mar;101(3):167-79. Epub 2008 Jan 25. PMID: 16822218

Article Published Date : Mar 01, 2008

Study Type : Animal Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Prostatic Hyperplasia, Testosterone-Induced

[+]

Pumpkin seed is effective in controlling gastrointestinal helminths in naturally infected ostriches.Jun 08, 2012

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Pubmed Data : Trop Anim Health Prod. 2012 Jun 9. Epub 2012 Jun 9. PMID: 22684690

Article Published Date : Jun 08, 2012

Study Type : Animal Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Helminthiasis, Parasitic Intestinal Diseases

Pharmacological Actions : Antiparasitic Agents

[+]

Pumpkin seed may prevent the risk of colon cancer when consumed in dietary proportions.Dec 31, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Toxicol. 2018 ;2018:6086490. Epub 2018 Sep 2. PMID: 30245714

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Colon Cancer, Colon Cancer: Prevention

Pharmacological Actions : Chemopreventive

Additional Keywords : Dietary Modification

[+]

Pumpkin seed oil can block testosterone induced increases in prostate size and protein synthesis. Jan 01, 2006

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Pubmed Data : Urol Int. 2006;77(3):269-74. PMID: 17033217

Article Published Date : Jan 01, 2006

Study Type : Animal Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Prostatic Hyperplasia, Testosterone-Induced, Prostatic Hyperplasia: Benign

[+]

Pumpkin seed oil contributes to the beneficial effect of an ACE-inhibitor and Calcium-Channel Blocker in the treatment of hypertension. May 01, 2000

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Pubmed Data : Pharmacol Res. 2000 May;41(5):555-63. PMID: 10753555

Article Published Date : May 01, 2000

Study Type : Animal Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Hypertension

[+]

Pumpkin seed oil exhibits an antihypertensive and cardioprotective effects.Jan 31, 2012

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Pubmed Data : J Med Food. 2012 Feb ;15(2):180-9. Epub 2011 Nov 14. PMID: 22082068

Article Published Date : Jan 31, 2012

Study Type : Animal Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Hypertension

Pharmacological Actions : Antihypertensive Agents, Cardioprotective, Malondialdehyde Down-regulation

[+]

Pumpkin seed oil improves lipid profile and cardiovascular outcomes in female rats. Jul 01, 2008

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Pubmed Data : Phytother Res. 2008 Jul;22(7):873-7. PMID: 18567058

Article Published Date : Jul 01, 2008

Study Type : Animal Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Hyperlipidemia

[+]

Pumpkin seed oil may have a protective role against BPA genotoxicity and histopathological alterations in male mice.Dec 31, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Toxicol Rep. 2018 ;5:857-863. Epub 2018 Aug 17. PMID: 30167376

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Bisphenol Toxicity

Pharmacological Actions : Genoprotective

Problem Substances : Bisphenol A

[+]

Pumpkin seed oil reduces the symptoms of arthritis as effectively as indomethacin, without causing liver damage. Jan 01, 1995

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Pubmed Data : Pharmacol Res. 1995 Jan;31(1):73-9. PMID: 7784309

Article Published Date : Jan 01, 1995

Study Type : Animal Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Arthritis

Additional Keywords : Natural Substances Versus Drugs

[+]

Pumpkin seed protein isolate administration is effective in alleviating the detrimental effects associated with protein malnutrition and acetaminophen intoxication.Aug 31, 2006

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Pubmed Data : Phytother Res. 2006 Sep ;20(9):780-3. PMID: 16807884

Article Published Date : Aug 31, 2006

Study Type : Animal Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Acetaminophen (Tylenol) Toxicity , Protein Malnourishment

Pharmacological Actions : Antioxidants, Hepatoprotective

Additional Keywords : Plant Extracts

[+]

Pumpkin seed protein isolate has significant antioxidant activity. May 01, 2009

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Pubmed Data : Arch Biochem Biophys. 2009 May 1;485(1):63-71. Epub 2009 Feb 20. PMID: 16909447

Article Published Date : May 01, 2009

Study Type : Animal Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Oxidative Stress

[+]

Pumpkin seed protein isolate protects against CCl4-induced liver injury in low-protein fed rats.Mar 31, 2005

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Pubmed Data : Phytother Res. 2005 Apr ;19(4):341-5. PMID: 16041732

Article Published Date : Mar 31, 2005

Study Type : Animal Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Chemically-Induced Liver Damage

Pharmacological Actions : Hepatoprotective

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Pumpkin seeds has an antiparasitic effect against canine tapeworms. Oct 01, 2004

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Pubmed Data : Rev Gastroenterol Peru. 2004 Oct-Dec;24(4):323-7. PMID: 15614300

Article Published Date : Oct 01, 2004

Study Type : Animal Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Parasitic Intestinal Diseases, Tapeworm Infection

[+]

T. occidentalis attenuated the deleterious effects of alcohol to the cyto-architecture of the testis.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Toxicol Rep. 2015 ;2:968-975. Epub 2015 Jun 18. PMID: 28962436

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Pumpkin

Diseases : Alcohol Toxicity , Testicular Injury: Chemical/Metal Induced

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation

[+]

Telfairia occidentalis pulp extract mitigates rifampicin-isoniazid-induced hepatotoxicity.Dec 31, 2018

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Pubmed Data : J Integr Med. 2019 Jan ;17(1):46-56. Epub 2018 Dec 1. PMID: 30555014

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Pumpkin

Diseases : Chemically-Induced Liver Damage, Tuberculosis Drug Induced Toxicity

Pharmacological Actions : Antioxidants, Hepatoprotective

[+]

The administration of the extract together with and after the administration of gentamycin reverses renal damage caused by gentamycin.Dec 31, 2016

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Pubmed Data : J Basic Clin Physiol Pharmacol. 2017 Jan 1 ;28(1):11-17. PMID: 27658143

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Pumpkin

Diseases : Chemotherapy-Induced Toxicity: Gentamicin

Pharmacological Actions : Chemoprotective Agents, Renoprotective

Additional Keywords : Plant Extracts

[+]

The combined administration of pumpkin polysaccharides and puerarin could synergistically ameliorate T2DM.Mar 07, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2019 Mar 8 ;24(5). Epub 2019 Mar 8. PMID: 30857163

Article Published Date : Mar 07, 2019

Study Type : Animal Study

Additional Links

Substances : Puerarin, Pumpkin

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Hypoglycemic Agents

Additional Keywords : Natural Substance Synergy, Polysaccharides

[+]

The present study provides valuable evidence on the possible health benefits of Mayan plant foods.Jan 07, 2021

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Pubmed Data : J Sci Food Agric. 2021 Jan 8. Epub 2021 Jan 8. PMID: 33420740

Article Published Date : Jan 07, 2021

Study Type : Animal Study

Additional Links

Substances : Achiote, Guava, Pumpkin, Radish

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Hypoglycemic Agents

[+]

The results suggest that Telfairia occidentalis-induced lowering of plasma glucose afterone week of treatment.Dec 29, 2018

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Pubmed Data : Niger J Physiol Sci. 2018 Dec 30 ;33(2):169-175. Epub 2018 Dec 30. PMID: 30837771

Article Published Date : Dec 29, 2018

Study Type : Animal Study

Additional Links

Substances : Pumpkin

Diseases : Hyperglycemia

Pharmacological Actions : Hypoglycemic Agents

Additional Keywords : Plant Extracts

[+]

This study brought to limelight the medicinal importance of fluted pumpkin seed in erectile functions.Sep 08, 2019

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Pubmed Data : J Food Biochem. 2019 Sep 9:e13037. Epub 2019 Sep 9. PMID: 31502274

Article Published Date : Sep 08, 2019

Study Type : Animal Study

Additional Links

Substances : Pumpkin

Diseases : Erectile Dysfunction

[+]

This study showed the significance of oil from pumpkin seeds as a promising drug to healing wounds in animal assays.Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Lipids Health Dis. 2016 ;15(1):73. Epub 2016 Apr 11. PMID: 27068642

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Pumpkin

Diseases : Wound Healing

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Plant Oils

[+]

A review of herbal preparations for the treatment of hair loss.Nov 02, 2019

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Pubmed Data : Arch Dermatol Res. 2019 Nov 3. Epub 2019 Nov 3. PMID: 31680216

Article Published Date : Nov 02, 2019

Study Type : Review

Additional Links

Substances : Ginger, Ginseng, Ginseng (Korean), Pumpkin, Red Clover, Saw Palmetto

Diseases : Alopecia, Hair Loss

[+]

Anti-proliferative and apoptotic effects of hull-less pumpkin extract on human papillary thyroid carcinoma cell line.Jan 27, 2021

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Pubmed Data : Anat Cell Biol. 2021 Jan 28. Epub 2021 Jan 28. PMID: 33504684

Article Published Date : Jan 27, 2021

Study Type : In Vitro Study

Additional Links

Substances : Pumpkin

Diseases : Thyroid Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Antioxidants and health-beneficial nutrients in fruits of eighteen Cucurbita cultivars.Apr 13, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2020 Apr 14 ;25(8). Epub 2020 Apr 14. PMID: 32295156

Article Published Date : Apr 13, 2020

Study Type : In Vitro Study

Additional Links

Substances : Pumpkin

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants

[+]

Effect of dietary inclusion of pumpkin seed on nephrotoxicity occasioned by cisplatin in experimental rats.Aug 17, 2020

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Pubmed Data : J Food Biochem. 2020 Aug 18:e13439. Epub 2020 Aug 18. PMID: 32808341

Article Published Date : Aug 17, 2020

Study Type : In Vitro Study

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Substances : Pumpkin

Diseases : Chemotherapy-Induced Toxicity: Cisplatin

Pharmacological Actions : Chemoprotective Agents

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Effect of roasting on the antioxidant activity, phenolic composition, and nutritional quality of pumpkin seeds.Dec 31, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Nutr. 2021 ;8:647354. Epub 2021 Mar 10. PMID: 33777995

Article Published Date : Dec 31, 2020

Study Type : In Vitro Study

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Substances : Pumpkin

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants

[+]

In vitro role of pumpkin parts as pharma-Foods: antihyperglycemic and antihyperlipidemic activities.Dec 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Food Sci. 2022 ;2022:4804408. Epub 2022 Aug 2. PMID: 35959224

Article Published Date : Dec 31, 2021

Study Type : In Vitro Study

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Substances : Pumpkin

Diseases : Hyperglycemia, Hyperlipidemia

Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic

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Phytochemical analysis and antioxidant activity of the seed of Telfairia occidentalis.Jan 31, 2018

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Pubmed Data : Nat Prod Res. 2018 Feb ;32(4):444-447. Epub 2017 Mar 31. PMID: 28361553

Article Published Date : Jan 31, 2018

Study Type : In Vitro Study

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Substances : Pumpkin

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants

[+]

Polysaccharides from pumpkin have antioxidant and cytoprotective effects. Oct 14, 2013

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Pubmed Data : Carbohydr Polym. 2013 Oct 15 ;98(1):686-91. Epub 2013 Jun 29. PMID: 23987399

Article Published Date : Oct 14, 2013

Study Type : In Vitro Study

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Substances : Pumpkin

Diseases : Hydrogen Peroxide Induced Toxicity, Oxidative Stress

Pharmacological Actions : Antioxidants, Cytoprotective

Additional Keywords : Polysaccharides

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Pumpkin (Cucurbita ficifolia Bouché) extract attenuate the adipogenesis in human mesenchymal stem cells by controlling adipogenic gene expression.Apr 30, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Saudi J Biol Sci. 2019 May ;26(4):744-751. Epub 2018 Oct 2. PMID: 31048999

Article Published Date : Apr 30, 2019

Study Type : In Vitro Study

Additional Links

Substances : Pumpkin

Diseases : Obesity

Additional Keywords : Anti-Obesity Agents, Gene Expression Regulation

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Pumpkin polysaccharides: Purification, characterization and hypoglycemic potential.Aug 06, 2019

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Pubmed Data : Int J Biol Macromol. 2019 Aug 7 ;139:842-849. Epub 2019 Aug 7. PMID: 31400422

Article Published Date : Aug 06, 2019

Study Type : In Vitro Study

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Substances : Pumpkin

Pharmacological Actions : Antioxidants, Hypoglycemic Agents, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation

Additional Keywords : Polysaccharides

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Pumpkin seed extract had growth inhibition effects on hyperplastic and some cancer cell lines. Mar 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Fitoterapia. 2016 Apr ;110:150-6. Epub 2016 Mar 11. PMID: 26976217

Article Published Date : Mar 31, 2016

Study Type : In Vitro Study

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Substances : Pumpkin, Pumpkin Seeds

Diseases : Breast Cancer, Colon Cancer, Prostate Cancer, Prostatic Hyperplasia: Benign

Pharmacological Actions : Antiproliferative

Additional Keywords : Plant Extracts

[+]

Pumpkin-seed oil possesses effective antischistosomal activity against various stages of S. mansoni.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Infect Drug Resist. 2020 ;13:3469-3484. Epub 2020 Oct 7. PMID: 33116667

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Pumpkin Seed Oil/Meal

Diseases : Schistosomiasis

Pharmacological Actions : Antiparasitic Agents

[+]

The use of pumpkin seed could be beneficial in the treatment of lower urinary tract symptoms related to benign prostatic hyperplasia.Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Arch Ital Urol Androl. 2016 ;88(2):136-43. Epub 2016 Jul 4. PMID: 27377091

Article Published Date : Dec 31, 2015

Study Type : Review

Additional Links

Substances : Pumpkin

Diseases : Lower Urinary Tract Symptoms, Prostatic Hyperplasia: Benign

Pharmacological Actions : Anti-Androgen, Anti-Inflammatory Agents

[+]

These results suggest that the pumpkin extracts may have immunomodulatory effects.Sep 30, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Res Pharm Sci. 2012 Oct ;7(4):217-24. PMID: 23248672

Article Published Date : Sep 30, 2012

Study Type : In Vitro Study

Additional Links

Substances : Pumpkin

Pharmacological Actions : Immunomodulatory

Additional Keywords : Dose Response, Plant Extracts

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View the Evidence: 64 Abstracts with Pumpkin Research

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C. maxima may decrease high blood glucose level fast and effective in diabetic critically ill patients.May 31, 2018

Consumption of C. ficifolia and probiotic yogurt may help treatment of diabetic patients.Dec 31, 2015

consumption of specific green leafy vegetables and other vegetables might be associated with a reduced risk of lung cancer. Dec 31, 2013

Cucurbita pepo-Rhus aromatica-Humulus lupulus combination reduces overactive bladder symptoms in women.Jun 30, 2019

Findings of the present trial provide evidence of a promising potential role of pumpkin seed oil in treating female pattern hair loss.Feb 04, 2021

Oral combination of pumpkin seed extract, soy germ isoflavonoids, and cranberry could be beneficial for benign prostate hyperplasia patients.Dec 31, 2019

Pumpkin seed consumption contributes to alleviating iron-deficiency associated anemia. Jul 01, 1995

Pumpkin seed oil (prostafit) is effective and a safe alternative treatment in benign prostatic hyperplasia.May 31, 2014

Pumpkin seed oil and saw palmetto oil may be effective as complementary and alternative medicine treatments for benign prostatic hyperplasia.Dec 31, 2008

Pumpkin seed oil extracted from C. maxima has the potential for prevention or treatment of urinary disorders.Dec 31, 2013

Pumpkin seed oil has beneficial properties in postmenopausal women. May 05, 2011

Pumpkin seeds reduce calcium-oxalate crystal occurence in the urine of children. Jan 01, 1987

Tryptophan-rich gourd seeds are a potential anxiolytic to those suffering from social phobia.Sep 01, 2007

Tryptophan-rich gourd seeds significantly improve subjective and objective measurements of insomnia.Apr 01, 2005

Cucurmosin has potential anticancer activity for human hepatoma.Dec 31, 2011

Pumpkin seed oil-loaded niosomes for topical application: 5α-reductase inhibitory, anti-inflammatory, and in vivo anti-hair loss effects.Jul 26, 2022

A flax and pumpkin seed mixture has anti-atherogenic and hepatoprotective effects. Dec 01, 2008

A purified polysaccharide from pumpkin fruit directly induces apoptotic cell death of HepG2 cells.Jun 16, 2017

Accelerating effect of Cucurbita pepo L. fruit extract on excisional wound healing.Aug 14, 2022

Animal's studies showed that oxidized oils decreased the whole body weight, which was ameliorated by the co-administration of un-oxidized oils. Dec 31, 2016

Antinociceptive and antioxidant activities of the methanolic extract of Telfairia occidentalis seeds.Sep 30, 2016

Beneficial effects of pumpkin seed oil as a topical hair growth promoting agent in a mice model.Oct 31, 2019

Cucumis sativus and Cucurbita maxima extract attenuate diabetes-induced hepatic and pancreatic injury in a rat model.Jul 31, 2020

Diets supplemented with raw and roasted pumpkin seeds improved some biochemical parameters associated with erectile function.Jan 31, 2021

Ellagic acid and pumpkin seed oil protects against methotrexate-induced small intestine damage in rats.Nov 30, 2011

Flax and Pumpkin seeds mixture supplemented in diet of diabetic rats may be helpful to prevent diabetes and its complications.Jul 31, 2010

Fluted pumpkin leaf extracts have hepatoprotective properties.Dec 31, 2004

Pumpkin (Cucurbita moschata) Fruit Extract Improves Physical Fatigue and Exercise Performance in Mice.Dec 31, 2011

Pumpkin fruit peel has a protective effect against carbon tetrachloride induced neurotoxicity.Oct 31, 2014

Pumpkin Seed contributes to inhibiting prostate growth. - Article 2Mar 01, 2008

Pumpkin seed is effective in controlling gastrointestinal helminths in naturally infected ostriches.Jun 08, 2012

Pumpkin seed may prevent the risk of colon cancer when consumed in dietary proportions.Dec 31, 2017

Pumpkin seed oil can block testosterone induced increases in prostate size and protein synthesis. Jan 01, 2006

Pumpkin seed oil contributes to the beneficial effect of an ACE-inhibitor and Calcium-Channel Blocker in the treatment of hypertension. May 01, 2000

Pumpkin seed oil exhibits an antihypertensive and cardioprotective effects.Jan 31, 2012

Pumpkin seed oil improves lipid profile and cardiovascular outcomes in female rats. Jul 01, 2008

Pumpkin seed oil may have a protective role against BPA genotoxicity and histopathological alterations in male mice.Dec 31, 2017

Pumpkin seed oil reduces the symptoms of arthritis as effectively as indomethacin, without causing liver damage. Jan 01, 1995

Pumpkin seed protein isolate administration is effective in alleviating the detrimental effects associated with protein malnutrition and acetaminophen intoxication.Aug 31, 2006

Pumpkin seed protein isolate has significant antioxidant activity. May 01, 2009

Pumpkin seed protein isolate protects against CCl4-induced liver injury in low-protein fed rats.Mar 31, 2005

Pumpkin seeds has an antiparasitic effect against canine tapeworms. Oct 01, 2004

T. occidentalis attenuated the deleterious effects of alcohol to the cyto-architecture of the testis.Dec 31, 2014

Telfairia occidentalis pulp extract mitigates rifampicin-isoniazid-induced hepatotoxicity.Dec 31, 2018

The administration of the extract together with and after the administration of gentamycin reverses renal damage caused by gentamycin.Dec 31, 2016

The combined administration of pumpkin polysaccharides and puerarin could synergistically ameliorate T2DM.Mar 07, 2019

The present study provides valuable evidence on the possible health benefits of Mayan plant foods.Jan 07, 2021

The results suggest that Telfairia occidentalis-induced lowering of plasma glucose afterone week of treatment.Dec 29, 2018

This study brought to limelight the medicinal importance of fluted pumpkin seed in erectile functions.Sep 08, 2019

This study showed the significance of oil from pumpkin seeds as a promising drug to healing wounds in animal assays.Dec 31, 2015

A review of herbal preparations for the treatment of hair loss.Nov 02, 2019

Anti-proliferative and apoptotic effects of hull-less pumpkin extract on human papillary thyroid carcinoma cell line.Jan 27, 2021

Antioxidants and health-beneficial nutrients in fruits of eighteen Cucurbita cultivars.Apr 13, 2020

Effect of dietary inclusion of pumpkin seed on nephrotoxicity occasioned by cisplatin in experimental rats.Aug 17, 2020

Effect of roasting on the antioxidant activity, phenolic composition, and nutritional quality of pumpkin seeds.Dec 31, 2020

In vitro role of pumpkin parts as pharma-Foods: antihyperglycemic and antihyperlipidemic activities.Dec 31, 2021

Phytochemical analysis and antioxidant activity of the seed of Telfairia occidentalis.Jan 31, 2018

Polysaccharides from pumpkin have antioxidant and cytoprotective effects. Oct 14, 2013

Pumpkin (Cucurbita ficifolia Bouché) extract attenuate the adipogenesis in human mesenchymal stem cells by controlling adipogenic gene expression.Apr 30, 2019

Pumpkin polysaccharides: Purification, characterization and hypoglycemic potential.Aug 06, 2019

Pumpkin seed extract had growth inhibition effects on hyperplastic and some cancer cell lines. Mar 31, 2016

Pumpkin-seed oil possesses effective antischistosomal activity against various stages of S. mansoni.Dec 31, 2019

The use of pumpkin seed could be beneficial in the treatment of lower urinary tract symptoms related to benign prostatic hyperplasia.Dec 31, 2015

These results suggest that the pumpkin extracts may have immunomodulatory effects.Sep 30, 2012

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View the Evidence:
64 Abstracts with Pumpkin Research