Quercetin

Name	AC	CK
Oxidative Stress	38	101
Cardiovascular Diseases	5	42
Hypertension	5	42
Obesity	16	42
Inflammation	19	41
Colorectal Cancer	5	33
Endothelial Dysfunction	4	24
Diabetes Mellitus: Type 2	8	22
Interstitial Cystitis	2	20
Rectal Cancer	1	20
DNA damage	9	18
Hyperuricemia	5	17
Liver Cancer	14	17
Aging	3	14
Breast Cancer	12	14
Pesticide Toxicity	3	14
Benzo[a]pyrene-induced Toxicity	3	13
Cancers: All	12	13
Pancreatic Cancer	12	13
Prostate Cancer	10	13
Cancers: Drug Resistant	10	12
Colon Polyps	2	12
Esophageal Cancer	3	12
Gastrointestinal polyps	2	12
Osteoarthritis	2	12
Arthritis: Rheumatoid	2	11
Cholesterol: Oxidation	2	11
Allergies	1	10
Cardiovascular Disease: Prevention	1	10
Chronic Pelvic Pain Syndrome	1	10
Cystitis: Interstitial	1	10
Diabetic Neuropathies	1	10
Endometrial Cancer	1	10
Erythema	1	10
Familial Adenomatous Polyposis	1	10
Fructose-Induced Toxicity	4	10
Graves Disease	1	10
High Fat Diet	5	10
Insulin Resistance	5	10
Itching	1	10
Kidney Cancer	1	10
Leukemia	8	10
Organ Transplantation: Kidney	1	10
Ovarian Cancer	8	10
Overweight	1	10
Painful Bladder Syndrome	1	10
Peripheral Neuropathies	1	10
Prostatitis: Chronic	1	10
Sarcoidosis	1	10
Smoking	1	10
Thrombosis	1	10
Ultraviolet Radiation Induced Damage	1	10
Urinary Tract Infections	1	10
Diabetic Complications	5	9
Melanoma	6	9
Mitochondrial Dysfunction	5	9
Alzheimer's Disease	5	8
Fluoride Toxicity	4	8
Lung Cancer	5	8
Neurodegenerative Diseases	5	8
Cancer Metastasis	5	7
Chemotherapy-Induced Toxicity: Cisplatin	5	7
Medulloblastoma	2	7
Radiation Induced Illness	4	7
Aluminum Toxicity	3	6
Breast Cancer: Triple Negative	4	6
Cancers: Multi-Drug Resistant	6	6
Chemically-Induced Liver Damage	3	6
Gastric Cancer	5	6
Ischemia	3	6
Kidney Damage	3	6
Liver Cancer: Prevention	4	6
Atherosclerosis	3	5
Cerebral Ischemia	3	5
Chronic Obstructive Pulmonary Disease	4	5
Colitis	3	5
Colon Cancer	3	5
Diabetes Mellitus: Type 1	4	5
Diabetic Retinopathy	3	5
Lipopolysaccharide-Induced Toxicity	4	5
Lymphoma	4	5
Wound Healing	3	5
Aneurysm: Aortic	2	4
Brain: Oxidative Stress	2	4
C-Reactive Protein	2	4
Cadmium Poisoning	2	4
Cancer Stem Cells	4	4
Chemotherapy-Induced Toxicity: Gentamicin	2	4
Chronic Lymphocytic Leukemia	3	4
Cognitive Decline/Dysfunction	2	4
Drug Toxicity: Methotrexate	2	4
Lipid Peroxidation	2	4
Manganese Poisoning	2	4
Neuropathic Pain	2	4
Parkinson's Disease	3	4
Arthritis	2	3
Asthma	2	3
Bisphenol Toxicity	2	3
Bisphenol-A Toxicity	2	3
Brain Inflammation	2	3
Carcinoma: Non-Small-Cell Lung	2	3
Cervical Cancer	3	3
Dyslipidemias	2	3
Epstein-Barr Virus Infections	2	3
Excitotoxicity	2	3
Glioma	2	3
High Fructose Diet	2	3
Hyperglycemia	2	3
Hyperlipidemia	2	3
Inflammatory Bowel Diseases	2	3
Metabolic Syndrome X	2	3
Mitochondrial Diseases	2	3
Oral Cancer	3	3
Prostate Cancer: Prevention	2	3
Scars	2	3
Testicular Injury: Cadmium-Induced	2	3
Acetaminophen (Tylenol) Toxicity	1	2
Acrylamide-induced toxicity	1	2
Advanced Glycation End products (AGE)	1	2
Aging: Brain	1	2
Air Pollution Linked Toxicity	1	2
Alcohol Toxicity	1	2
Alcohol Withdrawal	1	2
Alcoholic Liver Disease	1	2
Allergic Rhinitis	1	2
Anxiety	1	2
Asbestos Toxicity	2	2
Ascites	1	2
Athletic Performance	1	2
Bacterial Infections	1	2
Bone Fractures	1	2
Brain Injury: Traumatic	1	2
Cachexia	1	2
Cachexia: Cancer	1	2
Candida Albicans	1	2
Candidiasis: Vulvovaginal	1	2
Cardiac Hypertrophy	1	2
Cerebral Ischemia: Transient	1	2
Chemotherapy-Induced Toxicity: Kidney	1	2
Chemotherapy-Induced Toxicity: Paclitaxel	1	2
Cirrhosis	1	2
Depression	1	2
Diabetes: Cataract	1	2
Diabetic Nephropathy	1	2
Diesel Exhaust Particle Toxicity	1	2
Drug-Induced Toxicity	1	2
Drug-Induced Toxicity: Indomethacin	1	2
Drug-Induced Toxicity: Methotrexate	1	2
Dysbiosis	1	2
Ebola Virus Infections	1	2
Endometriosis	1	2
Enteropathy	1	2
Esophageal Reflux	1	2
Esophagitis	1	2
Eye Diseases	2	2
Fatty Liver	1	2
Furan Toxicity	1	2
Gastric Spasm	1	2
Gastroesophageal Reflux	1	2
Gastrointestinal Cancer	1	2
Glyphosate Toxicity	1	2
HIV Drug-Induced Toxicity	1	2
Heat Stroke	1	2
Hepatitis: Lectin-Induced (concanavalin)	1	2
Hepatopulmonary Syndrome	1	2
Homocysteine: Elevated	1	2
Huntington Disease	1	2
Hydrogen Peroxide Induced Toxicity	2	2
Hyperthyroidism	1	2
Immune Dysregulation: TH1/TH2 imbalance	1	2
Infertility: Male	1	2
Influenza in Swine	1	2
Intestinal Ischemia	1	2
Intestinal Permeability	2	2
Kidney Failure	1	2
Leaky Gut Syndrome	2	2
Melanoma: Metastatic	1	2
Memory Disorders: Sleep Deprivation Induced	1	2
Mercury Poisoning	1	2
Metabolic Diseases	1	2
Multiple Myeloma	1	2
Muscle Atrophy	1	2
Muscle Damage: Exercise-Induced	1	2
Myocardial Ischemia	1	2
Neurodevelopmental Disorders	1	2
Nicotine/Tobacco Toxicity	1	2
Non-Hodgkin's lymphoma: B Cell	2	2
Nonalcoholic fatty liver disease (NAFLD)	1	2
Periodontal Diseases	1	2
Petroleum Exposure And Toxicity	1	2
Phthalate Toxicity	1	2
Polychlorinated biphenyl toxicity	1	2
Promyelocytic leukemia	2	2
Pulmonary Fibrosis	1	2
Pulmonary Fibrosis: Bleomycin-Induced	1	2
Renal Failure: Acute	1	2
Rheumatoid Arthritis	1	2
Rhinovirus Infection	1	2
Sciatica	1	2
Seizures	1	2
Sepsis	1	2
Skin Cancer	1	2
Sleep Disorders	1	2
Sperm Count: Low	1	2
Spinal Cord Injuries	1	2
Squamous cell carcinoma	2	2
Staphylococcus aureus infection	2	2
Staphylococcus aureus: Methicillin-resistant (MRSA)	2	2
Statin-Induced Pathologies	1	2
Stroke	1	2
Stroke: Attenuation/Recovery	1	2
Swine Flu Associated Virus	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Thyroid Cancer	1	2
Traumatic Brain Injury	1	2
Tumors	1	2
Acid Reflux	1	1
Autoimmune Diseases	1	1
Avian Influenza	1	1
Benzene Toxicity	1	1
Bladder Cancer	1	1
Bone Diseases	1	1
Brain Cancer	1	1
Brain: Microglial Activation	1	1
Breast Cancer: Drug Resistant	1	1
Burns	1	1
Candida Infection	1	1
Cataract	1	1
Chemotherapy and Radiation Toxicity	1	1
Chemotherapy-Induced Toxicity: Cyclophosphamide	1	1
Chemotherapy-Induced Toxicity: Doxorubicin	1	1
Corneal Diseases	1	1
Diabetes Mellitus: Type 2: Prevention	1	1
Diabetic Neuropathy	1	1
Escherichia coli Infections	1	1
Estrogen Deficiency	1	1
Fungal Infections: Biofilm Formation/Resistance	1	1
Gastrointestinal Inflammation	1	1
Glaucoma	1	1
Glioblastoma	1	1
Gout	1	1
Head and Neck Cancer	1	1
Helicobacter Pylori Infection	1	1
Hepatitis C	1	1
High Cholesterol	1	1
Hyperinsulinism	1	1
Hypersensitivity	1	1
Hypoxia	1	1
Leishmaniasis	1	1
Leukemia: Chronic Lymphocytic Leukemia (CLL)	1	1
Liver Disease	1	1
Liver Diseases	1	1
Lymphoma: B-Cell	1	1
Macular Degeneration	1	1
Mesothelioma	1	1
Myocarditis: Autoimmune	1	1
Nasopharyngeal Cancer	1	1
Neutrophils: Elevated	1	1
Organ Transplantation	1	1
Osteosarcoma	1	1
Pancreatic Stem Cell	1	1
Periodontitis	1	1
Pseudomonas aeruginosa	1	1
Radiation	1	1
Retinal Diseases	1	1
Salmonella Infections	1	1
Streptococcus pyogenes	1	1
Teratoma	1	1
Tongue Cancer	1	1
Triglycerides: Elevated	1	1
Virally-Induced Cytokine Storm	1	1
Vitiligo	1	1
Weight Problems	1	1

Name	AC	CK
Antioxidants	90	254
Anti-Inflammatory Agents	51	99
Apoptotic	65	72
Chemopreventive	28	72
Neuroprotective Agents	28	57
Antiproliferative	48	56
Tumor Necrosis Factor (TNF) Alpha Inhibitor	15	34
Antihypertensive Agents	3	31
Anti-Apoptotic	11	29
Hepatoprotective	13	25
Anti-metastatic	16	24
Anticarcinogenic Agents	11	24
Cardioprotective	8	23
Interleukin-6 Downregulation	14	23
Chemosensitizer	18	21
Antineoplastic Agents	9	20
Cell cycle arrest	19	20
NF-kappaB Inhibitor	12	20
Renoprotective	10	20
Enzyme Inhibitors	6	16
Interleukin-1 beta downregulation	9	16
Chemoprotective Agents	9	14
Interleukin-8 downregulation	4	13
MicroRNA modulator	9	13
Anti-Allergic Agents	2	12
Matrix metalloproteinase-9 (MMP-9) inhibitor	8	12
Nrf2 activation	7	12
Hypolipidemic	2	11
Anti-thrombotic	1	10
Chemotherapeutic	9	10
Dermatologic Agents	1	10
Heme oxygenase-1 up-regulation	5	10
Nitric Oxide Enhancer	1	10
Photoprotective	1	10
Uricosuric Agents	1	10
Anti-Bacterial Agents	7	9
Cyclooxygenase 2 Inhibitors	6	9
Gastroprotective	5	9
Radioprotective	6	9
Superoxide Dismutase Up-regulation	5	9
Cytoprotective	4	8
Immunomodulatory	6	8
Genoprotective	4	7
Hypoglycemic Agents	4	7
Matrix metalloproteinase-2 (MMP-2) inhibitor	5	7
Angiogenesis Inhibitors	4	6
Interleukin-10 downregulation	3	6
Malondialdehyde Down-regulation	3	6
Tumor Suppressor Protein p53 Upregulation	4	6
Vascular Endothelial Growth Factor A Inhibitor	4	6
Antimutagenic Agents	1	5
Antiviral Agents	3	5
Gastrointestinal Agents	3	5
Antimicrobial	4	4
Bcl-2 protein down-regulation	3	4
Multidrug Resistance Gene Modulators	4	4
Radiosensitizer	3	4
STAT3 Inhibitor	3	4
AMP-activated protein kinase modulation	2	3
Anti-atherogenic	2	3
Antifungal Agents	2	3
Autophagy Up-regulation	3	3
Prophylactic Agents	2	3
Vascular Endothelial Growth Factor Inhibitors	2	3
Wnt/β-catenin signaling pathway modulation	3	3
Analgesics	1	2
Anti-Angiogenic	2	2
Anti-Anxiety Agents	1	2
Anti-Cachexic Agents	1	2
Anti-Fibrotic	1	2
Anti-Glycation Agents	1	2
Anticholesteremic Agents	1	2
Anticonvulsants	1	2
Antidepressive Agents	1	2
Antispasmodic	1	2
Autophagy Inhibitors	1	2
Bax/Bcl2 ratio: Increase	2	2
Brain-derived neurotrophic factor modulator	1	2
Calcium Channel Blockers	1	2
Chelating Agents	1	2
Cyclin D1 Down-Regulation	2	2
Epidermal growth factor receptor (EGFR) inhibitor	1	2
Excitatory Amino Acid Agonists	1	2
Insulin Sensitizers	1	2
Interleukin-17 downregulation	1	2
Interleukin-4 downregulation	1	2
NF-E2-Related Factor-2 (Nrf2) Modulator	1	2
Neuritogenic	1	2
Nitric Oxide Inhibitor	1	2
Pancreato Protective Agents	1	2
Postaglandin PGE2 downregulation	1	2
Proteasome Inhibitors	2	2
Protein Kinase Inhibitors	1	2
SIRT1 Activator	1	2
Vascular Cell Adhesion Molecule-1 Inhibitor	1	2
Vasodilator Agents	1	2
Alpha-amylase inhibitor	1	1
Alpha-glucosidase inhibitor	1	1
Anti-Adipogenic	1	1
Anti-Proliferative	1	1
Caspase-3 Activation	1	1
Cell Differentiation Inducer	1	1
Estrogen Receptor Modulators	1	1
Gluconeogenesis Inhibitor	2	1
Glucose transporter-2 (GLUT2) expression down-regulation	1	1
Glucose transporter-5 (GLUT5) expression down-regulation	1	1
Glutathione Upregulation	1	1
Heme oxygenase-1 inducer	1	1
Histone deacetylase inhibitor	1	1
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	1	1
Hypoxia-inducible factor-1 (HIF-1) inhibitor	1	1
Immunosuppressive Agents	1	1
Interleukin-1 alpha downregulation	1	1
Osteoprotective	1	1
Phase II Detoxification Enzyme Inducer	1	1
Phosphodiesterase Inhibitors	1	1
Proton Pump Inhibitor	1	1
VEGFR3 inhibition	1	1
Vascular Endothelial Growth Factor Regulator	1	1
Xanthine oxidase inhibitor	1	1

[+]

High intake of flavonols may reduce the risk of colon cancer and high intake of flavones may reduce the risk of rectal cancer.Jul 22, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Eur J Clin Nutr. 2015 Jun 10. Epub 2015 Jun 10. PMID: 26059745

Click here to read the entire abstract

Pubmed Data : J Med Food. 2015 Dec ;18(12):1327-32. Epub 2015 Sep 1. PMID: 26325006

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Pubmed Data : Pharmazie. 2005 Sep;60(9):696-700. PMID: 16222871

Article Published Date : Sep 01, 2005

Study Type : Human Study

Additional Links

Substances : Melatonin, NAC (N-acetyl-L-cysteine), Quercetin

Diseases : Graves Disease

Pharmacological Actions : Antioxidants

[+]

Onion peel extract consumption may be beneficial for obese individuals as a means of reducing oxidative stress to eventually prevent chronic diseases.Aug 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Cancer Prev. 2015 Sep ;20(3):202-7. PMID: 26473159

Article Published Date : Aug 31, 2015

Study Type : Human Study

Additional Links

Substances : Onion, Quercetin

Diseases : Obesity, Oxidative Stress

Pharmacological Actions : Antioxidants

Additional Keywords : Anti-Obesity Agents, Plant Extracts

[+]

People who preferentially consume high amounts of quercetin-containing foods have a reduced risk of thrombosis and potential CVD risk.Aug 31, 2006

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Pubmed Data : Br J Nutr. 2006 Sep ;96(3):482-8. PMID: 16925853

Article Published Date : Aug 31, 2006

Study Type : Human Study

Additional Links

Substances : Flavonoids, Onion, Quercetin, Soup

Diseases : Cardiovascular Disease: Prevention, Cardiovascular Diseases, Thrombosis

Pharmacological Actions : Anti-thrombotic, Cardioprotective

[+]

Quercetin and isoflavone intake is associated with a reduced risk for endometrial cancer. Sep 01, 2009

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Pubmed Data : Cancer Causes Control. 2009 Sep;20(7):1117-27. Epub 2009 Apr 8. PMID: 19353280

Article Published Date : Sep 01, 2009

Study Type : Human Study

Additional Links

Substances : Isoflavones, phytoestrogens, Quercetin

Diseases : Endometrial Cancer

[+]

Quercetin and rutin may ameliorate insecticide induced oxidative stress in human erythrocytes.Mar 01, 2010

Additional Keywords : Risk Reduction

[+]

The flavonoid quercetin may prevent renal cell cancer among male smokers. Aug 03, 2009

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Pubmed Data : Am J Epidemiol. 2009 Aug 3. PMID: 19651663

Article Published Date : Aug 03, 2009

Study Type : Human Study

Additional Links

Substances : Quercetin

Diseases : Kidney Cancer, Smoking

Pharmacological Actions : Chemopreventive

[+]

Pharmacological Actions : Chemopreventive, Tumor Suppressor Protein p53 Upregulation

Additional Keywords : Chemical: Lindane

[+]

Additional Keywords : Gene Expression Regulation

[+]

Ameliorative effects of quercetin on folliculogenesis in diabetic mice.Dec 30, 2019

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Pubmed Data : Gynecol Endocrinol. 2019 Dec 31:1-5. Epub 2019 Dec 31. PMID: 31889455

Article Published Date : Dec 30, 2019

Study Type : Animal Study

Additional Links

Substances : Quercetin

Diseases : Diabetic Complications

[+]

An isocaloric carbohydrate restriction diet and natural AMPK activating agents induce synergistic anticancer effects.Mar 18, 2015

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Pubmed Data : Eur J Cancer Prev. 2015 Mar 19. Epub 2015 Mar 19. PMID: 25747515

Article Published Date : Mar 18, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Basic Clin Physiol Pharmacol. 2015 May 1 ;26(3):237-51. PMID: 25918918

Article Published Date : Apr 30, 2015

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Pubmed Data : Exp Ther Med. 2017 Dec ;14(6):5942-5948. Epub 2017 Oct 18. PMID: 29285143

Article Published Date : Nov 30, 2017

Study Type : Animal Study

Additional Links

Substances : Quercetin, Resveratrol

Diseases : High Fat Diet, Obesity

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Anti-Obesity Agents

[+]

Combining green tea polyphenols and quercetin significantly enhanced the antiproliferative and proapoptotic effect in vivo. Dec 31, 2013

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Pubmed Data : J Nutr Biochem. 2014 Jan ;25(1):73-80. Epub 2013 Oct 10. PMID: 24314868

Article Published Date : Nov 30, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Gold (nanoparticles), Quercetin

Diseases : Breast Cancer, Breast Cancer: Triple Negative

Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic

[+]

Green tea and quercetin could enhance the therapeutic effect of Doc in a less-toxic manner.Dec 31, 2015

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Pubmed Data : J Exp Clin Cancer Res. 2016 ;35(1):73. Epub 2016 May 6. PMID: 27151407

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Green Tea, Quercetin

Diseases : Prostate Cancer

Pharmacological Actions : Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Docetaxel

[+]

[+]

Melatonin, curcumin, quercetin, and resveratrol ameliorate chemically-induced kidney damage.Dec 01, 2007

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Pubmed Data : Neuro Endocrinol Lett. 2007 Dec;28(6):739-44. PMID: 18684806

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Pubmed Data : J Nutr. 2009 Jul;139(7):1339-46. Epub 2009 Jun 3. PMID: 19494027

Article Published Date : Jul 01, 2009

Study Type : Animal Study

Additional Links

Substances : Quercetin

Diseases : Cirrhosis, Hepatopulmonary Syndrome

Pharmacological Actions : Antioxidants

[+]

Quercetin alleviated dehydroepiandrosterone-induced polycystic ovarian syndrome.Mar 10, 2020

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Pubmed Data : J Basic Clin Physiol Pharmacol. 2020 Mar 11. Epub 2020 Mar 11. PMID: 32160160

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2019 ;10:1544. Epub 2020 Jan 17. PMID: 32009956

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Quercetin

Diseases : Depression, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Antidepressive Agents, Brain-derived neurotrophic factor modulator

[+]

Quercetin ameliorated bisphenol A induced testicular steroidogenesis.Dec 31, 2017

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Pubmed Data : Toxicol Res (Camb). 2018 Jan 1 ;7(1):22-31. Epub 2017 Sep 14. PMID: 30090559

Article Published Date : Dec 31, 2017

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Pubmed Data : Nutrients. 2017 Jul 19 ;9(7). Epub 2017 Jul 19. PMID: 28753942

Article Published Date : Jul 18, 2017

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea, Quercetin

Diseases : High Fat Diet, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Gene Expression Regulation

[+]

Quercetin and low level laser therapy promote wound healing process in diabetic rats.Feb 20, 2018

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Pubmed Data : Biomed Pharmacother. 2018 Feb 21 ;101:58-73. Epub 2018 Feb 21. PMID: 29477473

Article Published Date : Feb 20, 2018

Pubmed Data : Food Chem Toxicol. 2014 Sep ;71:183-96. Epub 2014 Jun 19. PMID: 24953551

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Toxicol. 2018 ;2018:2817036. Epub 2018 May 16. PMID: 29861723

Article Published Date : Dec 31, 2017

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Pubmed Data : Biomed Pharmacother. 2017 Feb ;86:570-582. Epub 2016 Dec 24. PMID: 28027533

Article Published Date : Jan 31, 2017

Study Type : Animal Study

Additional Links

Substances : Quercetin

Diseases : Diabetic Complications, Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Cardioprotective

Problem Substances : Insulin

[+]

Quercetin could protect against pantoprazole sodium induced enteropathic damage in a dose dependent manner.Oct 21, 2016

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Pubmed Data : Exp Toxicol Pathol. 2016 Oct 22. Epub 2016 Aug 22. PMID: 27780667

Article Published Date : Oct 21, 2016

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Pubmed Data : Food Funct. 2018 Jan 2. Epub 2018 Jan 2. PMID: 29292417

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Diabetes Res. 2016 ;2016:8492780. Epub 2016 Nov 15. PMID: 27975068

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Quercetin, Toona sinensis

Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2, Diabetic Complications

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, NF-kappaB Inhibitor

Additional Keywords : Risk Reduction

[+]

Quercetin has a certain therapeutic effect on rats with diabetic retinopathy.Nov 30, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

[+]

Quercetin has a protective effect in the management of alcohol withdrawal reactions. Sep 01, 2002

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Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2002 Sep;48(6):685-92. PMID: 16176153

Article Published Date : Sep 01, 2002

Study Type : Animal Study

Additional Links

Substances : Quercetin

Diseases : Alcohol Withdrawal

[+]

Quercetin has a protective effect on atherosclerosis via enhancement of autophagy.Sep 30, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2016 Jun 14. Epub 2016 Jun 14. PMID: 27329589

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Indian J Pharmacol. 2016 Mar-Apr;48(2):168-71. PMID: 27127319

Article Published Date : Feb 29, 2016

Study Type : Animal Study

Additional Links

Substances : Quercetin

Diseases : Chemotherapy-Induced Toxicity: Cisplatin

Pharmacological Actions : Chemoprotective Agents

Additional Keywords : Chemotherapeutic Synergy: Cisplatin

[+]

Quercetin improves blood-brain barrier dysfunction in rats with cerebral ischemia reperfusion via Wnt signaling pathway.Dec 31, 2018

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Pubmed Data : Am J Transl Res. 2019 ;11(8):4683-4695. Epub 2019 Aug 15. PMID: 31497191

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Pubmed Data : Eur Rev Med Pharmacol Sci. 2010 Nov;14(11):903-14. PMID: 21284339

Article Published Date : Nov 01, 2010

Study Type : Animal Study

Additional Links

Substances : Quercetin, Vitamin C, Vitamin E

Diseases : Cadmium Poisoning

Pharmacological Actions : Antioxidants, Renoprotective

Additional Keywords : Natural Substance Synergy

[+]

Quercetin increased the cellular absorption of epigallocatechin gallate (EGCG) four-fold in A549 cells with a decreased methylation rate from 63 to 19%.May 31, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Food Funct. 2012 Jun ;3(6):635-42. PMID: 22438067

Article Published Date : May 31, 2012

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Quercetin

Diseases : Lung Cancer

Pharmacological Actions : Antiproliferative , Chemopreventive

Additional Keywords : Bioavailability, Natural Substance Synergy

[+]

Click here to read the entire abstract

Pubmed Data : Eur Heart J. 2011 Jul 20. Epub 2011 Jul 20. PMID: 21775390

Article Published Date : Jul 20, 2011

Study Type : Animal Study

Additional Links

Substances : Quercetin

Diseases : Drug-Induced Toxicity , Statin-Induced Pathologies

Problem Substances : Atorvastatin, Statin Drugs

Adverse Pharmacological Actions : Myotoxicity

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Quercetin is able to protect BEAS-2B cells from hexavalent chromium-induced carcinogenesis.Jun 16, 2016

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Pubmed Data : Oncotarget. 2016 Jun 17. Epub 2016 Jun 17. PMID: 27344173

Article Published Date : Jun 16, 2016

Study Type : Animal Study, In Vitro Study

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Substances : Quercetin

Diseases : Cancers: All

Pharmacological Actions : Anticarcinogenic Agents, MicroRNA modulator

Additional Keywords : Dose Response

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Quercetin is able to significantly alleviate the toxicity induced by acrylamide in rats.Jan 31, 2017

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Pubmed Data : Biomed Pharmacother. 2017 Feb ;86:705-714. Epub 2016 Dec 28. PMID: 28039850

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Quercetin possesses antioxidant protective activity against furan induced oxidative damage and stimulates the immune function.Nov 25, 2016

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Pubmed Data : Environ Sci Pollut Res Int. 2016 Nov 26. Epub 2016 Nov 26. PMID: 27889890

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Pubmed Data : Exp Ther Med. 2017 Dec ;14(6):6169-6175. Epub 2017 Oct 18. PMID: 29285175

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Pubmed Data : Biol Pharm Bull. 2009 Jan;32(1):61-7. PMID: 19122282

Article Published Date : Jan 01, 2009

Study Type : Animal Study

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Substances : Quercetin

Diseases : Chemotherapy-Induced Toxicity: Gentamicin, Chemotherapy-Induced Toxicity: Kidney, Oxidative Stress

Pharmacological Actions : Antioxidants, Renoprotective

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Quercetin protects against heat stroke-induced myocardial injury.Jan 15, 2017

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Pubmed Data : Chem Biol Interact. 2017 Jan 16. Epub 2017 Jan 16. PMID: 28104348

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Quercetin supplementation is effective in improving mitochondrial dysfunctions induced by 3-nitropropionic acid: implications in Huntington's disease.Feb 28, 2013

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Pubmed Data : Biochim Biophys Acta. 2013 Mar ;1832(3):421-30. Epub 2012 Dec 4. PMID: 23220257

Article Published Date : Feb 28, 2013

Study Type : Animal Study

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Substances : Quercetin

Diseases : Huntington Disease, Lipid Peroxidation, Mitochondrial Dysfunction

Pharmacological Actions : Antioxidants, Superoxide Dismutase Up-regulation

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Pubmed Data : Acta Neurochir (Wien). 2016 Mar 9. Epub 2016 Mar 9. PMID: 26960544

Article Published Date : Mar 08, 2016

Study Type : Animal Study

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Substances : Quercetin

Diseases : Neuropathic Pain, Sciatica

Additional Keywords : Superiority of Natural Substances versus Drugs

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Quercetin will be a good candidate for the supplement on the management and treatment of allergic diseases.May 19, 2016

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Pubmed Data : BMC Complement Altern Med. 2016 May 20 ;16:132. Epub 2016 Aug 20. PMID: 27207147

Article Published Date : May 19, 2016

Study Type : Animal Study

Additional Links

Substances : Quercetin

Diseases : Allergic Rhinitis

Pharmacological Actions : Anti-Allergic Agents, Neuritogenic

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Quercetin, a pneumolysin inhibitor, protects mice against Streptococcus pneumoniae infection.Feb 29, 2020

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Pubmed Data : Microb Pathog. 2020 Mar ;140:103934. Epub 2019 Dec 17. PMID: 31862394

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Pubmed Data : Arch Neurol. 2003 Feb;60(2):194-200. PMID: 15831530

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Pubmed Data : Int J Pediatr Otorhinolaryngol. 2015 Sep 28. Epub 2015 Sep 28. PMID: 26434546

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Targeted near infrared hyperthermia combined with immune stimulation could significantly improve the effect of hyperthermia.Feb 08, 2016

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Pubmed Data : Iran J Basic Med Sci. 2019 May ;22(5):499-505. PMID: 31217929

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Pubmed Data : Nutrition. 2020 Mar 5 ;78:110792. Epub 2020 Mar 5. PMID: 32473529

Article Published Date : Mar 04, 2020

Study Type : Animal Study

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Substances : Flavonoids, Naringenin , Quercetin

Diseases : Diabetes: Oxidative Stress, Hyperglycemia

Pharmacological Actions : Antioxidants, Gastroprotective

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These findings suggest that quercetin exhibits a protective effect in STZ-induced hyperglycemic AA broilers via decreasing oxidative stress.Dec 31, 2019

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Pubmed Data : Psychoneuroendocrinology. 2020 Apr 10 ;116:104673. Epub 2020 Apr 10. PMID: 32334345

Article Published Date : Apr 09, 2020

Study Type : Animal Study

Additional Links

Substances : Polyphenols, Quercetin, Xanthohumol

Diseases : Depression, Stress

Pharmacological Actions : Antidepressive Agents, Brain-derived neurotrophic factor modulator, Gastrointestinal Agents, Neuroprotective Agents

Additional Keywords : Gut-brain Axis

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These results suggested that quercetin and cisplatin synergistically increased cellular toxicity in breast cancer cells.Jun 30, 2019

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Pubmed Data : Obstet Gynecol Sci. 2019 Jul ;62(4):242-248. Epub 2019 Jun 19. PMID: 31338341

Article Published Date : Jun 30, 2019

Study Type : Animal Study

Additional Links

Substances : Quercetin

Diseases : Breast Cancer

Pharmacological Actions : Antiproliferative , Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Cisplatin

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Various plant phenols inhibit benzo[a]pyrene-induced nuclear a.berrations in mammalian intestinal cellsJan 01, 1985

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Pubmed Data : Food Chem Toxicol. 1985 Jan;23(1):47-9. PMID: 4038681

Article Published Date : Jan 01, 1985

Study Type : Animal Study

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Substances : Curcumin, Ellagic Acid, Quercetin

Diseases : Benzo[a]pyrene-induced Toxicity , Gastrointestinal Cancer

Pharmacological Actions : Chemopreventive

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View the Evidence: 558 Abstracts with Quercetin Research

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High intake of flavonols may reduce the risk of colon cancer and high intake of flavones may reduce the risk of rectal cancer.Jul 22, 2018

Quercetin intake resulted in significantly decreased blood pressure in humans.Jan 05, 2020

The current meta-analysis demonstrated that quercetin supplementation significantly reduced systolic plod pressure and VCAM-1 levels.May 11, 2019

A combination of glucosamine sulfate, sodium hyaluronate, chondroitin sulfate, quercetin and rutin improve symptoms of interstitial cystitis/painful bladder syndrome. Sep 24, 2008

A combination of glucosamine, chondroitin and quercetin significantly improve the symptoms of osteoarthritis and rheumatoid arthritis. Feb 01, 2009

A combination of polyphenols reduced diastolic pressure by potentiating eNOS activation and nitric oxide production.Jun 09, 2015

A combination of quercetin, ascorbyl palmitate and vitamin D appears to safely offer relief of symptomatic diabetic neuropathy.Sep 01, 2005

A combination of Saw Palmetto, Nettle, Curcumin and Quercetin significantly improves treatment outcome of prulifloxacin in bacterial prostatitis patients. Jun 01, 2009

A single dose of mango leaf extract in combination with quercetin enhances peak power output during repeated sprint exercise.Oct 27, 2019

Bioflavonoid therapy with curcumin and quercetin improves cadaveric renal transplantation in humans. Dec 15, 2005

Flavonoid intake and the risk of age-related cataract in China's Heilongjiang Province.Dec 31, 2014

Flavonol intake and cognitive decline in middle-aged adults.Nov 30, 2015

Mango leaf extract with quercetin attenuates muscle damage and accelerates recovery after strenuous exercise. Feb 25, 2020

Medium-term administration of onion peel extract an improvement in flow-mediated dilation and circulating endothelial progenitor cells.Aug 31, 2015

Melatonin, quercetin and NAC are beneficial in reducing oxidative stress in the patients with Grave's Disease. Sep 01, 2005

Onion peel extract consumption may be beneficial for obese individuals as a means of reducing oxidative stress to eventually prevent chronic diseases.Aug 31, 2015

People who preferentially consume high amounts of quercetin-containing foods have a reduced risk of thrombosis and potential CVD risk.Aug 31, 2006

Quercetin and isoflavone intake is associated with a reduced risk for endometrial cancer. Sep 01, 2009

Quercetin and rutin may ameliorate insecticide induced oxidative stress in human erythrocytes.Mar 01, 2010

Quercetin is able to reduce redness, itching, and inflammation of damaged skin; it may also help restore skin barrier function.Dec 31, 2015

Quercetin is well tolerated and provided significant symptomatic improvement in patients with interstitial cystitis. Mar 01, 2001

Quercetin lowers plasma uric acid in pre-hyperuricaemic males. Jan 19, 2016

Quercetin reduced systolic blood pressure and plasma oxidised LDL concentrations in overweight subjects with a high-cardiovascular risk phenotype.Oct 01, 2009

Quercetin significantly improves antioxidant status of patients with sarcoidosis.Nov 14, 2008

Sea buckthorn leaf extracts protect neuronal PC-12 cells from oxidative stress.Jul 27, 2017

Selected antioxidants have a protective effect against beta-cyfluthrin-induced oxidative stress in human erythrocytes in vitro.Apr 01, 2010

The combination of curcumin and quercetin appears to reduce the number and size of ileal and rectal adenomas in patients with Familialadenomatous polyposis without appreciable toxicity. Aug 01, 2006

The combination of hyaluronic acid, chondroitin sulfate, curcumin and quercetin was effective in preventing recurrent urinary tract infections.Nov 30, 2016

The flavonoid quercetin may prevent renal cell cancer among male smokers. Aug 03, 2009

The results of the present study indicate that a dietary pattern characterised by the intake of lignans, quercetin and resveratrol may play a protective role in the development of oesophageal cancersNov 30, 2014

The results suggest that quercetin-rich onion may be beneficial for preventing obesity and improving liver function.Dec 27, 2019

These findings suggest that chronic onion extract intake ameliorates postprandial endothelial dysfunctionDec 31, 2012

These results elucidated that apple pectin immediately enhanced quercetin absorption in human subjects.May 27, 2015

This comparison study found that 166mg of quercetin from a supplement would be comparable to about 10 mg of quercetin aglycone equivalents from onion.May 12, 2015

An aqueous horseradish extract and its main flavonoids, kaempferol and quercetin has great potential to protect DNA from damage. Dec 31, 2013

Quercetin and ascorbic acid suppress fructose-induced NLRP3 inflammasome activation.Mar 21, 2017

Quercetin stimulates bone marrow mesenchymal stem cell differentiation through an estrogen receptor-mediated pathway.Jan 01, 2018

The antifibrotic effect of quercetin can be enhanced by adding methyl group on functionally important position.Dec 01, 2019

A diet rich in vitamin C and quercetin could prevent nicotine-induced toxicity.Nov 30, 2016

"Dietary polyphenols in cancer prevention: the example of the flavonoid quercetin in leukemia."Jun 30, 2012

"Quercetin inhibits diethylnitrosamine-induced hepatic preneoplastic lesions in rats."Jan 01, 2011

A combination of quercetin and resveratrol produces a brown-like remodeling effect in perirenal white adipose tissue.Nov 21, 2016

A combination of quercetin and resveratrol reduces obesity in high-fat diet-fed rats by modulation of gut microbiota.Dec 13, 2017

A combination of resveratrol and quercetin suppressed glomerular damage and apoptosis induced by acetaminophen in the kidney.Feb 02, 2020

A formulation of palmitoylethanolamide and quercetin decreases inflammation and relieves pain in inflammatory and osteoarthritic pain models.Aug 01, 2017

A quercetin, EGCG and apple polyphenol concentrate improved disorders of lipid metabolism and pro-oxidant-antioxidant homeostasis.Dec 31, 2016

A specific mixture of nutrients suppresses ovarian cancer A-2780 tumor incidence, growth, and metastasis to lungs.Mar 17, 2017

Administration of quercetin at 15mg/kg body weight resulted in a ~70% reduction in tumor growth.Dec 31, 2015

Allopurinol, quercetin and rutin ameliorate renal inflammasome activation and lipid accumulation in fructose-fed rats.Jun 30, 2012

Alternating consumption of β-glucan and quercetin reduces mortality in mice with colorectal cancer.Sep 30, 2019

Ameliorative effects of quercetin on folliculogenesis in diabetic mice.Dec 30, 2019

An isocaloric carbohydrate restriction diet and natural AMPK activating agents induce synergistic anticancer effects.Mar 18, 2015

Anthocyanin rich bilberry and blackcurrant diets favorably modulate altered amyloid precursor protein processing and alleviate behavioral abnormalities in a mouse model of AD.Dec 31, 2012

Anti-diabetic activity of quercetin extracted from Phyllanthus emblica L. fruit.Mar 31, 2018

Anti-fibrosis activity of quercetin attenuates rabbit tracheal stenosis via the TGF-β/AKT/mTOR signaling pathway.Mar 12, 2020

Antidepressant activity of flavonoid ethanol extract of Abelmoschus manihot corolla with BDNF up-regulation in the hippocampus.Jan 31, 2017

Antidiabetic cataract effects of Ginkgo biloba extract, rutin and quercetin are mediated by the inhibition of oxidative stress and polyol pathway.Dec 27, 2017

Apigenin and quercetin may have a therapeutic role in preventing and treating gastric spasm. Jul 03, 2009

Beyond its antioxidant properties: Quercetin targets multiple signalling pathways in hepatocellular carcinoma in rats.Oct 11, 2019

Bioactive dietary polyphenol preparations could be potential therapeutic agents in promoting resilience against sleep deprivation-induced cognitive dysfunction.Jul 29, 2015

Blackberry juice and quercetin together significantly reduced sodium fluoride induced oxidative and histological changes in rats.Apr 30, 2015

Both quercetin and isoliquiritigenin exhibited anti-cancer effects on Epstein-Barr virus associated gastric carcinoma.Sep 25, 2016

Catechin and quercetin have an ameliorative effect against organochlorine pesticide induced toxicity in male rats.Jun 01, 2010

Combination antiretroviral therapy (cART)-induced hippocampal disorders: Highlights on therapeutic potential of naringenin and quercetin.May 31, 2019

Combination treatment with quercetin and resveratrol attenuates high fat diet-induced obesity and associated inflammation.Nov 30, 2017

Combining green tea polyphenols and quercetin significantly enhanced the antiproliferative and proapoptotic effect in vivo. Dec 31, 2013

Consumption of diets rich in quercetin could be useful to counteract the adverse effects of high-fat diet-induced adipose dysfunction.Feb 03, 2020

Continuous exposure of pancreatic cancer cells to dietary bioactive agents does not induce drug resistance unlike chemotherapy.Dec 31, 2015

Curcumin inhibits radiation-induced changes in the liver. Dec 01, 2001

Dietary quercetin alleviated DSS-induced colitis.Jul 10, 2020

Dietary quercetin can prevent disuse muscle atrophy by targeting the mitochondria in skeletal muscle tissue.Feb 07, 2016

Effect of quercetin monoglycosides on oxidative stress and gut microbiota diversity in mice with dextran sodium sulphate-induced colitis.Dec 31, 2017

Quercetin

View the Evidence:
558 Abstracts with Quercetin Research