Rooibos

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66 Diseases Researched for Rooibos
NameACCKFocus
Diabetes Mellitus: Type 2730Locked
Aging Skin220Locked
Oxidative Stress819Locked
Cardiovascular Diseases313Locked
Inflammation812Locked
Diesel Exhaust Particle Toxicity 27Locked
Chemically-Induced Liver Damage35Locked
Diabetic Complications35Locked
Obesity35Locked
Neurodegenerative Diseases34Locked
Sepsis24Locked
Skin Cancer34Locked
Hyperglycemia23Locked
Prostate Cancer33Locked
Advanced Glycation End products (AGE)12Locked
Aging22Locked
Alcohol Toxicity 22Locked
Allergic Rhinitis12Locked
Asthma12Locked
Atopic Dermatitis12Locked
Bone Diseases12Locked
Bronchospasm: Acute12Locked
COPD12Locked
Cardiomyopathy12Locked
Chemotherapy-Induced Toxicity: Doxorubicin22Locked
Chronic Obstructive Pulmonary Disease12Locked
Cognitive Decline/Dysfunction12Locked
Colonic Spasm12Locked
Cortisol: High12Locked
Fatty Liver12Locked
Fluoride Toxicity 12Locked
Gastric Spasm12Locked
Gastrointestinal Diseases12Locked
HIV Drug-Induced Toxicity 12Locked
HIV Infections22Locked
Hemolytic Anemia12Locked
Hyperuricemia12Locked
Hypoglycemia12Locked
Insulin Resistance12Locked
Kidney Damage12Locked
Lipid Peroxidation12Locked
Mitochondrial Dysfunction 22Locked
Myocardial Ischemia12Locked
Osteoporosis12Locked
Prediabetes12Locked
Respiratory Diseases12Locked
Stroke: Attenuation/Recovery 12Locked
Tumors12Locked
Ultraviolet Radiation Induced Damage22Locked
Anxiety11Locked
Colon Cancer11Locked
Colorectal Cancer11Locked
Coronavirus Infection11Locked
DNA damage11Locked
Diabetes: Oxidative Stress11Locked
Endothelial Dysfunction11Locked
Heterocyclic Aromatic Amine Induced Toxicity11Locked
Immune Disorders: Low Immune Function11Locked
Leukemia11Locked
Liver Cancer11Locked
Metabolic Syndrome X11Locked
Mycotoxin Toxicity11Locked
Nicotine/Tobacco Toxicity 11Locked
Rotavirus Infections11Locked
Wound Healing: Delayed11Locked
Xenobiotic Exposures11Locked
39 Pharmacological Actions Researched for Rooibos
NameACCKFocus
Antioxidants2759Locked
Anti-Inflammatory Agents1832Locked
Hypoglycemic Agents628Locked
Cardioprotective711Locked
Neuroprotective Agents710Locked
NF-kappaB Inhibitor48Locked
Anti-Apoptotic47Locked
Interleukin-6 Downregulation36Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor36Locked
Antiproliferative 55Locked
Hepatoprotective35Locked
Antispasmodic24Locked
Nrf2 activation24Locked
Apoptotic33Locked
Hypolipidemic23Locked
Anti-Glycation Agents12Locked
Anticholesteremic Agents12Locked
Bronchodilator Agents12Locked
Gastrointestinal Agents12Locked
Gastroprotective12Locked
Hypotensive12Locked
Insulin Sensitizers12Locked
Nitric Oxide Inhibitor12Locked
Osteoprotective 12Locked
Pancreato Protective Agents12Locked
Renoprotective12Locked
Xanthine oxidase inhibitor12Locked
Alpha-glucosidase inhibitor 11Locked
Anti-Anxiety Agents11Locked
Anti-metastatic11Locked
Antiviral Agents11Locked
Cell cycle arrest11Locked
Chemopreventive11Locked
Chemoprotective Agents11Locked
Chemotherapeutic11Locked
Cyclooxygenase 2 Inhibitors11Locked
Detoxifier11Locked
Genoprotective11Locked
Postaglandin PGE2 downregulation 11Locked

View the Evidence:
76 Abstracts with Rooibos Research

[+]

Blood glucose levels were significantly reduced in diabetic rodent models treated with PPAG, a rooibos-associated phenolic compound.Apr 05, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2018 Apr 6 ;23(4). Epub 2018 Apr 6. PMID: 29642387
Article Published Date : Apr 05, 2018
Study Type : Meta Analysis, Review
Additional Links
Substances : Rooibos
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Rooibos tea improves the lipid profile and redox status of adults at risk of developing cardiovascular disease.Jan 07, 2011

Pubmed Data : J Ethnopharmacol. 2011 Jan 7 ;133(1):46-52. Epub 2010 Sep 15. PMID: 20833235
Article Published Date : Jan 07, 2011
Study Type : Human Study
Additional Links
Substances : Flavonoids, Polyphenols, Rooibos
Diseases : Cardiovascular Diseases, Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Supplementation with fermented honeybush could be helpful for protecting against skin aging.Sep 30, 2018

Pubmed Data : J Cosmet Laser Ther. 2018 Oct ;20(5):313-318. Epub 2018 Feb 1. PMID: 29388846
Article Published Date : Sep 30, 2018
Study Type : Human Study
Additional Links
Substances : Rooibos
Diseases : Aging Skin
Pharmacological Actions : Antioxidants
Additional Keywords : Phytotherapy, Plant Extracts
[+]

This study compares the anti-aging potential of ginkgo biloba and topical tea preparations.Apr 01, 2010

Pubmed Data : Int J Cosmet Sci. 2010 Apr ;32(2):99-106. PMID: 20412217
Article Published Date : Apr 01, 2010
Study Type : Human Study
Additional Links
Substances : Flavonoids, Ginkgo biloba, Green Tea, Rooibos
Diseases : Aging Skin
Additional Keywords : Plant Extracts
[+]

Herbal extracts offer protection against diesel exhaust particles-induced oxidative stress and inflammatory response.Mar 19, 2019

Pubmed Data : Phytomedicine. 2019 Mar 20 ;59:152898. Epub 2019 Mar 20. PMID: 30986715
Article Published Date : Mar 19, 2019
Study Type : Human In Vitro
Additional Links
Substances : Fermented Foods and Beverages, Honeybush, Rooibos
Diseases : Diesel Exhaust Particle Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Ameliorative effect of aspalathin and nothofagin from rooibos on HMGB1-induced septic responses.Dec 31, 2014

Pubmed Data : Am J Chin Med. 2015 ;43(5):991-1012. Epub 2015 Jul 30. PMID: 26224030
Article Published Date : Dec 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Phytotherapy
[+]

Ameliorative effect of aspalathin from rooibos on acute oxidative stress. Feb 14, 2013

Pubmed Data : Phytomedicine. 2013 Feb 15 ;20(3-4):380-6. Epub 2012 Dec 3. PMID: 23218401
Article Published Date : Feb 14, 2013
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Anti-inflammatory effects of aspalathin and nothofagin from rooibos.Jul 31, 2015

Pubmed Data : Inflammation. 2015 Aug ;38(4):1502-16. PMID: 25655391
Article Published Date : Jul 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Aspalathin and Nothofagin from Rooibos (Aspalathus linearis) inhibits high glucose-induced inflammation in vitro and in vivo.Jan 31, 2015

Pubmed Data : Inflammation. 2015 Feb ;38(1):445-55. PMID: 25338943
Article Published Date : Jan 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Diabetic Complications, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

Aspalathin and other rooibos flavonoids trapped α-dicarbonyls and inhibited formation of advanced glycation end products.Nov 24, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 Nov 25 ;23(23). Epub 2022 Nov 25. PMID: 36499065
Article Published Date : Nov 24, 2022
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Rooibos
Diseases : Advanced Glycation End products (AGE)
Pharmacological Actions : Anti-Glycation Agents
Additional Keywords : Plant Extracts
[+]

Aspalathin from rooibos improves the hypoglycemic potential of metformin in type 2 diabetic mice.Nov 13, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Physiol Res. 2018 Nov 14 ;67(5):813-818. Epub 2018 Jul 25. PMID: 30044119
Article Published Date : Nov 13, 2018
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Natural Substance/Drug Synergy
[+]

Aspalathin improves hyperglycemia and glucose intolerance in obese diabetic ob/ob mice.Aug 31, 2013

Pubmed Data : Eur J Nutr. 2013 Sep ;52(6):1607-19. Epub 2012 Dec 13. PMID: 23238530
Article Published Date : Aug 31, 2013
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Hypoglycemia
Pharmacological Actions : Hypoglycemic Agents
[+]

Aspalathin protects the heart against hyperglycemia-induced oxidative damage.Jan 13, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2017 Jan 14 ;22(1). Epub 2017 Jan 14. PMID: 28098811
Article Published Date : Jan 13, 2017
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Hyperglycemia
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Nrf2 activation
[+]

Aspalathin, a compound found within Rooibos Tea, improves glucose tolerance, uptake and insulin secretion in a type 2 diabetes mouse model. Dec 01, 2010

Pubmed Data : Invest New Drugs. 2010 Dec;28(6):766-82. PMID: 19188054
Article Published Date : Dec 01, 2010
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Diabetes Mellitus: Type 2
[+]

Aspalathin-enriched green rooibos extract reduces hepatic insulin resistance.Jan 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Feb 1 ;20(3). Epub 2019 Feb 1. PMID: 30717198
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Insulin Resistance
Pharmacological Actions : Insulin Sensitizers
[+]

Aspalathin-rich green rooibos extract lowers LDL-cholesterol and oxidative status in high-fat diet-induced diabetes. May 01, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 May 2 ;24(9). Epub 2019 May 2. PMID: 31052590
Article Published Date : May 01, 2019
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Anticholesteremic Agents, Antioxidants, Hypoglycemic Agents, Hypolipidemic
[+]

Cardioprotective function of green rooibos.Dec 06, 2020

Pubmed Data : Planta Med. 2020 Dec 7. Epub 2020 Dec 7. PMID: 33285593
Article Published Date : Dec 06, 2020
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Myocardial Ischemia, Prediabetes
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective
[+]

Fermented rooibos may have a beneficial effect on bone health.May 22, 2018

Pubmed Data : Food Funct. 2018 May 23. Epub 2018 May 23. PMID: 29790498
Article Published Date : May 22, 2018
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Bone Diseases, Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective
[+]

Fermented rooibos tea ameliorates sodium fluoride-induced cardiorenal toxicity, oxidative stress, and inflammation.Feb 04, 2024

Pubmed Data : Cardiovasc Toxicol. 2024 Feb 5. Epub 2024 Feb 5. PMID: 38315346
Article Published Date : Feb 04, 2024
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Fluoride Toxicity , Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Problem Substances : Sodium Fluoride
[+]

Green rooibos promotes gut health: insight into mechanisms.Jan 29, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ethnopharmacol. 2024 Jan 30 ;319(Pt 3):117379. Epub 2023 Nov 2. PMID: 37923252
Article Published Date : Jan 29, 2024
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Gastrointestinal Diseases
Pharmacological Actions : Gastrointestinal Agents, Gastroprotective
[+]

Long-term administration of Aspalathus linearis infusion affects spatial memory. Apr 15, 2019

Pubmed Data : J Ethnopharmacol. 2019 Apr 16:111881. Epub 2019 Apr 16. PMID: 31002838
Article Published Date : Apr 15, 2019
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

Long-term consumption of fermented rooibos herbal tea offers neuroprotection against ischemic brain injury in rats.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Neurobiol Exp (Wars). 2017 ;77(1):94-105. PMID: 28379220
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Lipid Peroxidation, Stroke: Attenuation/Recovery
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Nothofagin suppresses mast cell-mediated allergic inflammation.Jan 24, 2019

Pubmed Data : Chem Biol Interact. 2019 Jan 25 ;298:1-7. Epub 2018 Oct 28. PMID: 30392763
Article Published Date : Jan 24, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Allergic Rhinitis, Asthma, Atopic Dermatitis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Phenylpropenoic acid glucoside from rooibos protects the beta cell mass exposed to acute diabetogenic stress.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(6):e0157604. Epub 2016 Jun 14. PMID: 27299564
Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Pancreato Protective Agents
[+]

Renal protective effects of aspalathin and nothofagin from rooibos in a sepsis model.Nov 30, 2018

Pubmed Data : Pharmacol Rep. 2018 Dec ;70(6):1195-1201. Epub 2018 Jul 27. PMID: 30340097
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Kidney Damage, Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Rooibos co-treatment ameliorated the harmful antiretroviral therapy-induced cardiovascular effects.Feb 06, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cardiovasc J Afr. 2019 Feb 7 ;30:1-8. Epub 2019 Feb 7. PMID: 30839048
Article Published Date : Feb 06, 2019
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : HIV Drug-Induced Toxicity
Pharmacological Actions : Cardioprotective
[+]

Rooibos tea ameliorates the carbon tetrachloride-induced injury to mitochondrial respiratory function and energy production in rat liver.Dec 31, 2018

Pubmed Data : Gen Physiol Biophys. 2019 Jan ;38(1):15-25. Epub 2019 Jan 18. PMID: 30657457
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

Rooibos tea has antispasmodic properties which may be of value in the treatment of hyperactive gastrointestinal disorders. Nov 01, 2006

Pubmed Data : Basic Clin Pharmacol Toxicol. 2006 Nov;99(5):365-73. PMID: 17076689
Article Published Date : Nov 01, 2006
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Colonic Spasm, Gastric Spasm
Pharmacological Actions : Antispasmodic
[+]

Rooibos tea is as effective as vitamin C in inhibiting experimentally-induced hemolysis of red blood cells in quails. Aug 01, 2000

Pubmed Data : Gynecol Oncol. 2000 Aug;78(2):181-6. PMID: 11409839
Article Published Date : Aug 01, 2000
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Hemolytic Anemia
[+]

Rooibos tea may have therapeutic potential in treating congestive respiratory ailments due to its bronchodilator, antispasmodic and blood pressure lowering effects. Dec 01, 2006

Pubmed Data : Eur J Nutr. 2006 Dec;45(8):463-9. Epub 2006 Nov 1. PMID: 17080260
Article Published Date : Dec 01, 2006
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Bronchospasm: Acute, Chronic Obstructive Pulmonary Disease, COPD, Respiratory Diseases
Pharmacological Actions : Antispasmodic, Bronchodilator Agents, Hypotensive
[+]

Rooibos tea reduces cortisol levels in rats.Mar 01, 2014

Pubmed Data : Mol Nutr Food Res. 2014 Mar ;58(3):537-49. Epub 2013 Sep 11. PMID: 24022885
Article Published Date : Mar 01, 2014
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Cortisol: High
Additional Keywords : Plant Extracts
[+]

Rooibos tea supports liver regeneration and reduces liver fibrosis following chemical injury. Sep 01, 2008

Pubmed Data : Gen Physiol Biophys. 2008 Sep;27(3):179-86. PMID: 18981533
Article Published Date : Sep 01, 2008
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Chemically-Induced Liver Damage
Additional Keywords : Liver Regeneration
[+]

Rooibos tea suppresses age-related accumulation of lipid peroxides in the rat brain. Aug 18, 1995

Pubmed Data : Neurosci Lett. 1995 Aug 18;196(1-2):85-8. PMID: 7501264
Article Published Date : Aug 18, 1995
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

Rooibos, Honeybush and Green Tea inhibit tumor promotion in mouse skin. Jun 28, 2005

Pubmed Data : Cancer Lett. 2005 Jun 28;224(2):193-202. Epub 2004 Dec 10. PMID: 15914270
Article Published Date : Jun 28, 2005
Study Type : Animal Study
Additional Links
Substances : Honeybush, Rooibos
Diseases : Skin Cancer, Tumors
[+]

The effects of a green Rooibos extract on metabolic parameters and adipose tissue biology in rats fed different obesogenic diets.Dec 12, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Funct. 2022 Dec 13 ;13(24):12648-12663. Epub 2022 Dec 13. PMID: 36441182
Article Published Date : Dec 12, 2022
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Obesity
Additional Keywords : Anti-Obesity Agents, Plant Extracts
[+]

The modulating effects of green rooibos extract on vascular function and antioxidant status in obese Wistar rats.Feb 17, 2021

Pubmed Data : Cardiovasc J Afr. 2021 Feb 18 ;32:1-11. Epub 2021 Feb 18. PMID: 33605975
Article Published Date : Feb 17, 2021
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Cardiovascular Diseases
Pharmacological Actions : Antioxidants
[+]

These findings suggest that a green rooibos extract has potential as an anti-steatotic, anti-inflammatory and weight reducing agent in vivo.Jun 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Histochem. 2019 Jul ;121(5):646-656. Epub 2019 May 29. PMID: 31153588
Article Published Date : Jun 30, 2019
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Fatty Liver, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective
Additional Keywords : Anti-Obesity Agents, Phytotherapy, Plant Extracts
[+]

This indicates the potential of rooibos extract to protect against diesel exhaust particles-induced cardiovascular toxicity.Feb 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Heliyon. 2019 Mar ;5(3):e01426. Epub 2019 Mar 28. PMID: 30976698
Article Published Date : Feb 28, 2019
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Diesel Exhaust Particle Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, NF-kappaB Inhibitor, Nrf2 activation
[+]

This study provides evidence that an aqueous extract of fermented rooibos protects cardiomyocytes.Apr 14, 2014

Pubmed Data : Phytomedicine. 2014 Apr 15 ;21(5):595-601. Epub 2013 Nov 20. PMID: 24268738
Article Published Date : Apr 14, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Cardiomyopathy, Diabetic Complications
Pharmacological Actions : Anti-Apoptotic, Cardioprotective
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Xanthine oxidase inhibitory activity and hypouricemic effect of aspalathin from unfermented rooibos.Nov 30, 2013

Pubmed Data : J Food Sci. 2013 Dec ;78(12):H1935-9. Epub 2013 Nov 21. PMID: 24261664
Article Published Date : Nov 30, 2013
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Hyperuricemia
Pharmacological Actions : Xanthine oxidase inhibitor
Additional Keywords : Plant Extracts
[+]

A polysaccharide from Rooibois leaves has a strong anti-HIV activity. Feb 01, 1997

Pubmed Data : Biosci Biotechnol Biochem. 1997 Feb;61(2):267-71. PMID: 9058964
Article Published Date : Feb 01, 1997
Study Type : In Vitro Study
Additional Links
Substances : Rooibos
Diseases : HIV Infections
[+]

A review of the potential of rooibos to prevent the metabolic syndrome.Jun 14, 2016

Pubmed Data : Crit Rev Food Sci Nutr. 2016 Jun 15:0. Epub 2016 Jun 15. PMID: 27305453
Article Published Date : Jun 14, 2016
Study Type : Review
Additional Links
Substances : Rooibos
Diseases : Metabolic Syndrome X
Additional Keywords : Gene Expression Regulation, Risk Reduction
[+]

Aspalathin ameliorates doxorubicin-induced oxidative stress in H9c2 cardiomyoblasts.Feb 28, 2019

Pubmed Data : Toxicol In Vitro. 2019 Mar ;55:134-139. Epub 2018 Dec 19. PMID: 30576852
Article Published Date : Feb 28, 2019
Study Type : In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Anti-Apoptotic, Cardioprotective
[+]

Aspalathin reverts doxorubicin-induced cardiotoxicity.Sep 21, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2017 Sep 22 ;22(10). Epub 2017 Sep 22. PMID: 28937626
Article Published Date : Sep 21, 2017
Study Type : In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Cardioprotective, Chemoprotective Agents
[+]

Aspalathin-rich green Aspalathus linearis extract suppresses migration and invasion of human castration-resistant prostate cancer.Mar 31, 2020

Pubmed Data : Phytomedicine. 2020 Apr ;69:153210. Epub 2020 Mar 18. PMID: 32217447
Article Published Date : Mar 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Prostate Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative
Additional Keywords : Plant Extracts
[+]

Aspalathus linearis suppresses cell survival and proliferation of enzalutamide-resistant prostate cancer cells.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2022 ;17(7):e0270803. Epub 2022 Jul 1. PMID: 35776912
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Prostate Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Aspalathus linearis targets adipocytes and obesity-associated inflammation.Apr 02, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2023 Apr 3 ;15(7). Epub 2023 Apr 3. PMID: 37049592
Article Published Date : Apr 02, 2023
Study Type : In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Inflammation, Obesity
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Anti-Obesity Agents, Plant Extracts
[+]

Differential cytotoxicity of rooibos and green tea extracts against primary rat hepatocytes and human liver and colon cancer cells.Sep 14, 2020

Pubmed Data : Nutr Cancer. 2020 Sep 15:1-15. Epub 2020 Sep 15. PMID: 32930006
Article Published Date : Sep 14, 2020
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate), Flavonoids, Green Tea, Rooibos
Diseases : Colon Cancer, Liver Cancer
Pharmacological Actions : Apoptotic
[+]

Effects of hot‑water extracts from 26 herbs on α‑glucosidase activity.Jul 30, 2020

Pubmed Data : Mol Med Rep. 2020 Jul 31. Epub 2020 Jul 31. PMID: 32945423
Article Published Date : Jul 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Green Tea, Rooibos, Willow Bark
Diseases : Diabetes Mellitus: Type 2, Hyperglycemia
Pharmacological Actions : Alpha-glucosidase inhibitor
[+]

Fruits and vegetables protect against the genotoxicity of heterocyclic aromatic amines activated by human xenobiotic-metabolizing enzymes expressed in immortal mammalian cells.Aug 14, 2010

Pubmed Data : Mutat Res. 2010 Aug 14. Epub 2010 Aug 14. PMID: 20713174
Article Published Date : Aug 14, 2010
Study Type : In Vitro Study
Additional Links
Substances : Black Tea, Blueberry, Fruit: All, Green Tea, Kiwifruit, Onion, Plum, Rooibos, Spinach, Vegetables: All
Diseases : Heterocyclic Aromatic Amine Induced Toxicity, Xenobiotic Exposures
Pharmacological Actions : Detoxifier, Genoprotective
[+]

Fumonisin B 1-induced mitochondrial toxicity and hepatoprotective potential of rooibos.Jul 14, 2020

Pubmed Data : J Appl Toxicol. 2020 Jul 15. Epub 2020 Jul 15. PMID: 32667064
Article Published Date : Jul 14, 2020
Study Type : Review
Additional Links
Substances : Rooibos
Diseases : Chemically-Induced Liver Damage, Mycotoxin Toxicity
Pharmacological Actions : Hepatoprotective
[+]

Generally used nutritional extracts of these plants have in vitro antiviral activity against rotavirus.Jul 25, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Virol J. 2012 Jul 26 ;9:137. Epub 2012 Jul 26. PMID: 22834653
Article Published Date : Jul 25, 2012
Study Type : In Vitro Study
Additional Links
Substances : Licorice, Lotus , Nettle, Olive, Rooibos
Diseases : Rotavirus Infections
Pharmacological Actions : Antiviral Agents
Additional Keywords : Antiviral Agents, Licorice, Lotus, Natural Substance Synergy, nettle, Olive, Plant Extracts, Rooibos, Rotavirus Infections
[+]

Green, black and rooibos tea inhibit prostaglandin E2 formation in human monocytes.Jan 07, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2022 Jan 8 ;27(2). Epub 2022 Jan 8. PMID: 35056712
Article Published Date : Jan 07, 2022
Study Type : In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Postaglandin PGE2 downregulation
[+]

Hibiscus, rooibos, and Yerba mate for healthy aging.Jun 06, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2022 Jun 7 ;11(12). Epub 2022 Jun 7. PMID: 35741873
Article Published Date : Jun 06, 2022
Study Type : Review
Additional Links
Substances : Hibiscus, Rooibos, Yerba Mate
Diseases : Aging, Neurodegenerative Diseases
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Identification of degranulation inhibitors from rooibos tea in rat basophilic leukaemia cells.Dec 19, 2017

Pubmed Data : Nat Prod Res. 2017 Dec 20:1-5. Epub 2017 Dec 20. PMID: 29262735
Article Published Date : Dec 19, 2017
Study Type : In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Leukemia
Pharmacological Actions : Chemotherapeutic
[+]

Impact of cold versus hot brewing on the phenolic profile and antioxidant capacity of rooibos herbal tea.Oct 20, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2019 Oct 21 ;8(10). Epub 2019 Oct 21. PMID: 31640245
Article Published Date : Oct 20, 2019
Study Type : In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Herbal Teas
[+]

Neuroprotective and anxiolytic potential of green rooibos ( Aspalathus linearis) polyphenolic extract.Dec 07, 2021

Pubmed Data : Food Funct. 2021 Dec 8. Epub 2021 Dec 8. PMID: 34877951
Article Published Date : Dec 07, 2021
Study Type : In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Anxiety
Pharmacological Actions : Anti-Anxiety Agents, Neuroprotective Agents
[+]

Oligosaccharides extracted from Rooibos tea have anti-HIV activity in vitro. Apr 01, 1997

Pubmed Data : Leukemia. 1997 Apr;11 Suppl 3:128-30. PMID: 9209319
Article Published Date : Apr 01, 1997
Study Type : In Vitro Study
Additional Links
Substances : Rooibos
Diseases : HIV Infections
[+]

Optimized Camellia sinensis var. sinensis, Ilex paraguariensis, and Aspalathus linearis blend presents high antioxidant and antiproliferative activities. Jul 14, 2018

Pubmed Data : Food Chem. 2018 Jul 15 ;254:348-358. Epub 2018 Feb 6. PMID: 29548463
Article Published Date : Jul 14, 2018
Study Type : In Vitro Study
Additional Links
Substances : Rooibos, White Tea, Yerba Mate
Diseases : Colorectal Cancer
Pharmacological Actions : Antioxidants, Antiproliferative
[+]

Potential therapeutic benefits of green and fermented rooibos in dermal wound healing.Jun 30, 2018

Pubmed Data : Planta Med. 2018 Jul ;84(9-10):645-652. Epub 2018 Feb 28. PMID: 29490385
Article Published Date : Jun 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages, Rooibos
Diseases : Diabetic Complications, Wound Healing: Delayed
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors
[+]

Protective effects of linearthin and other chalcone derivatives from Aspalathus linearis (Rooibos) against UVB induced oxidative stress.Sep 16, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Plants (Basel). 2021 Sep 17 ;10(9). Epub 2021 Sep 17. PMID: 34579468
Article Published Date : Sep 16, 2021
Study Type : In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Oxidative Stress, Ultraviolet Radiation Induced Damage
Pharmacological Actions : Antioxidants
[+]

Rooibos flavonoids ameliorate antimycin A-induced mitochondrial dysfunction.Oct 17, 2021

Pubmed Data : Molecules. 2021 Oct 18 ;26(20). Epub 2021 Oct 18. PMID: 34684871
Article Published Date : Oct 17, 2021
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Rooibos
Diseases : Mitochondrial Dysfunction
Pharmacological Actions : Antioxidants
[+]

Rooibos has significant antioxidant activity. Jan 01, 2009

Pubmed Data : J Oleo Sci. 2009;58(6):275-83. PMID: 19430189
Article Published Date : Jan 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Oxidative Stress
[+]

Rooibos is a functional food targeting cardiovascular disease.Sep 04, 2018

Pubmed Data : Food Funct. 2018 Sep 5. Epub 2018 Sep 5. PMID: 30183052
Article Published Date : Sep 04, 2018
Study Type : Review
Additional Links
Substances : Rooibos
Diseases : Cardiovascular Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective
[+]

Rooibos protects against nicotine induced vascular injury and oxidative stress.Feb 06, 2020

Pubmed Data : Cardiovasc J Afr. 2020 Feb 7 ;31:1-10. Epub 2020 Feb 7. PMID: 32031565
Article Published Date : Feb 06, 2020
Study Type : In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Endothelial Dysfunction, Nicotine/Tobacco Toxicity
Pharmacological Actions : Antioxidants
[+]

Rooibos suppresses proliferation of castration-resistant prostate cancer cells via inhibition of Akt signaling.Aug 07, 2019

Pubmed Data : Phytomedicine. 2019 Aug 8 ;64:153068. Epub 2019 Aug 8. PMID: 31419729
Article Published Date : Aug 07, 2019
Study Type : In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Prostate Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest
[+]

Rooibos tea could profoundly alter the redox status of brain endothelial cells. Jan 09, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Alcohol Clin Exp Res. 2020 10 ;44(10):1997-2007. Epub 2020 Sep 20. PMID: 32780433
Article Published Date : Jan 09, 2020
Study Type : In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Alcohol Toxicity
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Rooibos tea has an antoxidant and protective effect on DNA. Jul 01, 2010

Pubmed Data : J Altern Complement Med. 2010 Jul;16(7):807-9. PMID: 15630213
Article Published Date : Jul 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Rooibos
Diseases : DNA damage
[+]

Rooibos tea may boost antigen-specific antibody production in diseases involving a severe defectc in Th1 imjune response such as cancer, allergy, AIDS and other infections. Oct 01, 2001

Pubmed Data : Biosci Biotechnol Biochem. 2001 Oct;65(10):2137-45. PMID: 11758901
Article Published Date : Oct 01, 2001
Study Type : In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Immune Disorders: Low Immune Function
[+]

Rooibos tea-in the cross fire of ROS, mitochondrial dysfunction and loss of proteostasis-positioned for healthy aging.Mar 31, 2023

Pubmed Data : Biogerontology. 2023 Apr ;24(2):149-162. Epub 2023 Feb 13. PMID: 36781516
Article Published Date : Mar 31, 2023
Study Type : Review
Additional Links
Substances : Rooibos
Diseases : Aging, Mitochondrial Dysfunction , Neurodegenerative Diseases
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Rooibos, a supportive role to play during the COVID-19 pandemic?Oct 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Funct Foods. 2021 Nov ;86:104684. Epub 2021 Aug 17. PMID: 34422116
Article Published Date : Oct 31, 2021
Study Type : Review
Additional Links
Substances : Rooibos
Diseases : Coronavirus Infection
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

The anti-proliferative activity of green tea and rooibos methanol extracts is mainly mediated by the monomeric type flavonoids.Nov 24, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2016 Nov 25 ;21(12). Epub 2016 Nov 25. PMID: 27897996
Article Published Date : Nov 24, 2016
Study Type : In Vitro Study
Additional Links
Substances : Green Tea, Honeybush, Rooibos
Diseases : Skin Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Chemopreventive
[+]

The health benefits of rooibos tea in humans ( aspalathus linearis)-a scoping review.Dec 26, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Public Health Afr. 2023 Dec 27 ;14(12):2784. Epub 2023 Dec 1. PMID: 38204815
Article Published Date : Dec 26, 2023
Study Type : Review
Additional Links
Substances : Rooibos
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hypoglycemic Agents, Hypolipidemic
[+]

The indirect removal of UVB damaged keratinocytes by herbal tea extracts via apoptosis may find application in the prevention of photo-induced inflammation.Oct 01, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2016 Oct 2 ;21(10). Epub 2016 Oct 2. PMID: 27706097
Article Published Date : Oct 01, 2016
Study Type : In Vitro Study
Additional Links
Substances : Honeybush, Rooibos
Diseases : Inflammation, Skin Cancer, Ultraviolet Radiation Induced Damage
Pharmacological Actions : Anti-Inflammatory Agents
[+]

The potential of South African herbal teas, Rooibos and Honeybush in the management of type 2 diabetes mellitus.Dec 04, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2018 Dec 5 ;23(12). Epub 2018 Dec 5. PMID: 30563087
Article Published Date : Dec 04, 2018
Study Type : Review
Additional Links
Substances : Honeybush, Polyphenols, Rooibos
Diseases : Diabetes: Oxidative Stress, Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Hypoglycemic Agents
Additional Keywords : Herbal Teas, Plant Extracts
[+]

These results make rooibos leaves interesting for the preparation of a fermented beverage with health benefits.Dec 19, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Dec 20 ;11(1). Epub 2018 Dec 20. PMID: 30577416
Article Published Date : Dec 19, 2018
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages, Flavonoids, Polyphenols, Rooibos
Diseases : Alcohol Toxicity , Oxidative Stress
Pharmacological Actions : Antioxidants

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