Rosmarinic acid

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35 Diseases Researched for Rosmarinic acid
NameACCKFocus
Psoriasis15Locked
Asthma24Locked
Brain Inflammation 24Locked
Chemotherapy-Induced Toxicity: Doxorubicin24Locked
Diabetes Mellitus: Type 223Locked
Advanced Glycation End products (AGE)22Locked
Aging: Brain 12Locked
Alcohol Toxicity 12Locked
Allergic Rhinitis12Locked
Allergic Rhinoconjunctivitis12Locked
Amnesia: Drug-Induced12Locked
Amyloidosis12Locked
Brain: Oxidative Stress12Locked
Chemotherapy-Induced Toxicity: Gentamicin12Locked
Cholestasis12Locked
Colon Cancer12Locked
Diabetes: Memory Problems12Locked
Learning disorders12Locked
Lipopolysaccharide-Induced Toxicity12Locked
Liver Disease12Locked
Memory Disorders12Locked
Myocardial Fibrosis 12Locked
Myocardial Infarction12Locked
Neurodegenerative Diseases22Locked
Neuropathic Pain12Locked
Ulcerative Colitis12Locked
Alzheimer's Disease11Locked
Amyotrophic lateral sclerosis (ALS)11Locked
Enterovirus: Type 7111Locked
Huntington Disease11Locked
Lyme Borreliosis11Locked
Lyme Disease11Locked
Memory Disorders: Drug-Induced11Locked
Oxidative Stress11Locked
Parkinson's Disease11Locked
29 Pharmacological Actions Researched for Rosmarinic acid
NameACCKFocus
Anti-Inflammatory Agents615Locked
Interleukin-1 beta downregulation513Locked
NF-kappaB Inhibitor513Locked
Interleukin-6 Downregulation411Locked
Neuroprotective Agents611Locked
Antioxidants610Locked
Cyclooxygenase 2 Inhibitors48Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor27Locked
Chemoprotective Agents36Locked
Interleukin-8 downregulation15Locked
Hypoglycemic Agents23Locked
Anti-Allergic Agents12Locked
Antiproliferative 12Locked
Cardioprotective12Locked
Hepatoprotective12Locked
Interleukin-22 Downregulation12Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor12Locked
Nitric Oxide Inhibitor12Locked
Prostaglandin PGE2 downregulation12Locked
Renoprotective12Locked
SGLT1 inducer12Locked
STAT3 Inhibitor12Locked
Superoxide Dismutase Up-regulation12Locked
Anti-Glycation Agents11Locked
Antimicrobial11Locked
Antiviral Agents11Locked
Cytoprotective11Locked
Neuroplasticity enhancement11Locked
Nonpeptidyl Inhibitors11Locked

View the Evidence:
101 Abstracts with Rosmarinic acid Research

[+]

Safety and efficacy of Melissa officinalis extract containing rosmarinic acid in the prevention of Alzheimer's disease progression.Oct 28, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2020 Oct 29 ;10(1):18627. Epub 2020 Oct 29. PMID: 33122694
Article Published Date : Oct 28, 2020
Study Type : Human Study
Additional Links
Substances : Lemon Balm, Rosmarinic acid
Diseases : Alzheimer's Disease, Dementia
Pharmacological Actions : Neuroprotective Agents
[+]

Phytochemicals rosmarinic acid, ampelopsin, and amorfrutin-A can modulate Age-related phenotype of serially passaged human skin fibroblasts in vitro.Jan 01, 2019

Pubmed Data : Front Genet. 2019 ;10:81. Epub 2019 Feb 21. PMID: 30847003
Article Published Date : Jan 01, 2019
Study Type : Human In Vitro
Additional Links
Substances : Rosmarinic acid
Diseases : Aging Skin
Pharmacological Actions : Regenerative
[+]

Rosmarinic acid may be a potential candidate for the treatment of psoriasis.Jun 14, 2016

Pubmed Data : Life Sci. 2016 Jun 15 ;155:189-94. Epub 2016 May 17. PMID: 27210890
Article Published Date : Jun 14, 2016
Study Type : Human In Vitro
Additional Links
Substances : Rosmarinic acid
Diseases : Psoriasis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Rosmarinic acid exerts anti-inflammatory effect and relieves oxidative stress via Nrf2 activation in carbon tetrachloride-induced liver damage.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Nutr Res. 2022 ;66. Epub 2022 Nov 18. PMID: 36590857
Article Published Date : Dec 31, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Rosmarinic acid-loaded nanotechnology-based therapy through the nasal route could be promising approach for the treatment of neurodegenerative disorders.Nov 11, 2018

Pubmed Data : Neurochem Int. 2018 Nov 12 ;122:47-58. Epub 2018 Nov 12. PMID: 30439384
Article Published Date : Nov 11, 2018
Study Type : Human: Case Report
Additional Links
Substances : Rosmarinic acid
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

Protective effects of rosmarinic acid on doxorubicin-induced testicular damage.Dec 31, 2013

Pubmed Data : Chemotherapy. 2014 ;60(1):7-12. Epub 2014 Oct 4. PMID: 25301265
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin, Oxidative Stress, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants, Chemoprotective Agents, Malondialdehyde Down-regulation
[+]

Black rice anthocyanin-rich extract and rosmarinic acid may provide a promising dietary approach for the management of inflammatory bowel disease.May 22, 2018

Pubmed Data : Food Funct. 2018 May 23 ;9(5):2796-2808. PMID: 29691532
Article Published Date : May 22, 2018
Study Type : Animal Study
Additional Links
Substances : Anthocyanins, Brown Rice, Rosmarinic acid
Diseases : Colitis, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Co-administration of antioxidant significantly increased plasma level of curcumin in animal models.Nov 25, 2015

Pubmed Data : Mol Nutr Food Res. 2015 Nov 26. Epub 2015 Nov 26. PMID: 26608515
Article Published Date : Nov 25, 2015
Study Type : Animal Study
Additional Links
Substances : Caffeic Acid, Curcumin, Gallic Acid, Rosmarinic acid, Vitamin C
Diseases : Colon Cancer
Pharmacological Actions : Antioxidants, Antiproliferative
Additional Keywords : Increased Bioavailability, Metabolites
[+]

Combination therapy of rosmarinic acid and lycopene shows better protective effects than the corresponding monotherapy.Nov 23, 2016

Pubmed Data : Anat Rec (Hoboken). 2016 Nov 24. Epub 2016 Nov 24. PMID: 27884046
Article Published Date : Nov 23, 2016
Study Type : Animal Study
Additional Links
Substances : Lycopene, Rosmarinic acid
Diseases : Chemotherapy-Induced Toxicity: Gentamicin
Pharmacological Actions : Chemoprotective Agents, Renoprotective
Additional Keywords : Chemoprotective Agents, Chemotherapy-Induced Toxicity: Gentamicin, lycopene, Renoprotective, Rosmarinic acid
[+]

Dietary rosmarinic acid supplementation may be beneficial in terms of improving cholestasis-related liver injury.Aug 04, 2017

Pubmed Data : Food Chem Toxicol. 2017 Aug 5 ;108(Pt A):214-223. Epub 2017 Aug 5. PMID: 28789951
Article Published Date : Aug 04, 2017
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Cholestasis, Liver Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, NF-kappaB Inhibitor
[+]

Effect of p-cymene and rosmarinic acid on gastric ulcer healing - Involvement of multiple endogenous curative mechanisms.Feb 15, 2021

Pubmed Data : Phytomedicine. 2021 Feb 16:153497. Epub 2021 Feb 16. PMID: 33745762
Article Published Date : Feb 15, 2021
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents, Cyclooxygenase 2 Inhibitors, Gastroprotective, Interleukin-1 beta downregulation, Transforming growth factor beta (TGF-β) upregulation
[+]

Effects of rosmarinic acid on methotrexate-induced nephrotoxicity and hepatotoxicity.Apr 30, 2021

Pubmed Data : Indian J Nephrol. 2021 May-Jun;31(3):218-224. Epub 2021 Jan 27. PMID: 34376933
Article Published Date : Apr 30, 2021
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Drug Toxicity: Methotrexate, Kidney Damage: Drug-Induced, Liver Damage: Drug-Induced
Pharmacological Actions : Hepatoprotective, Renoprotective
Problem Substances : Methotrexate
[+]

Ellagic acid and rosmarinic acid attenuate doxorubicin-induced testicular injury in rats.Jun 05, 2017

Pubmed Data : J Biochem Mol Toxicol. 2017 Jun 6. Epub 2017 Jun 6. PMID: 28586512
Article Published Date : Jun 05, 2017
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid, Rosmarinic acid
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Chemoprotective Agents
[+]

Ellagic acid and rosmarinic acid can effectively protect against doxorubicin induced neurotoxicity.Aug 15, 2017

Pubmed Data : J Biochem Mol Toxicol. 2017 Aug 16. Epub 2017 Aug 16. PMID: 28815802
Article Published Date : Aug 15, 2017
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid, Rosmarinic acid
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Chemoprotective Agents
[+]

Extracts from spearmint and rosemary have beneficial effects on learning and memory and brain tissue markers of oxidation.Aug 11, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Physiol Behav. 2016 Aug 12. Epub 2016 Aug 12. PMID: 27527000
Article Published Date : Aug 11, 2016
Study Type : Animal Study
Additional Links
Substances : Carnosic Acid, Rosemary, Rosmarinic acid, Spearmint
Diseases : Aging: Brain , Brain: Oxidative Stress, Learning disorders, Memory Disorders
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Extracts of R. officinalis and rosmarinic acid through modulating neuro-inflammation might be potential candidates in treating neuropathic pain.Dec 21, 2016

Pubmed Data : Biomed Pharmacother. 2016 Dec 22 ;86:441-449. Epub 2016 Dec 22. PMID: 28012923
Article Published Date : Dec 21, 2016
Study Type : Animal Study
Additional Links
Substances : Rosemary, Rosmarinic acid
Diseases : Brain Inflammation , Neuropathic Pain
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Matrix metalloproteinase-2 (MMP-2) inhibitor, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation
Additional Keywords : Plant Extracts
[+]

Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats.Oct 13, 2021

Pubmed Data : Nat Prod Res. 2021 Oct 14:1-7. Epub 2021 Oct 14. PMID: 34647501
Article Published Date : Oct 13, 2021
Study Type : Animal Study
Additional Links
Substances : Marjoram, Rosmarinic acid
Diseases : Hyperglycemia
Pharmacological Actions : Hypoglycemic Agents
[+]

In vivo and in vitro protective effects of rosmarinic acid against doxorubicin-induced cardiotoxicity.Jun 03, 2021

Pubmed Data : Nutr Cancer. 2021 Jun 4:1-15. Epub 2021 Jun 4. PMID: 34085575
Article Published Date : Jun 03, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Chemoprotective Agents
[+]

Lemon balm and rosmarinic acid could improve liver damage by non-alcoholic lipid accumulation and may be promising medications to treat NASH.Apr 21, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Apr 22 ;12(4). Epub 2020 Apr 22. PMID: 32331258
Article Published Date : Apr 21, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lemon Balm, Rosmarinic acid
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Fibrotic, Hepatoprotective
[+]

Lemon balm extract and its major chemical compound, rosmarinic acid, alleviate damages of liver.May 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Dev Nutr. 2019 Jun ;3(Suppl 1). Epub 2019 Jun 13. PMID: 31223844
Article Published Date : May 31, 2019
Study Type : Animal Study
Additional Links
Substances : Lemon Balm, Rosmarinic acid
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, NF-kappaB Inhibitor, Nrf2 activation
[+]

Natural phenolic compounds have anti-amyloidogenic effects on Aβ in addition to well-known anti-oxidative and anti-inflammatory effects.Dec 31, 2014

Pubmed Data : Adv Exp Med Biol. 2015 ;863:79-94. PMID: 26092627
Article Published Date : Dec 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin, Ferulic acid, Myricetin, Nordihydroguaiaretic acid (NDGA), Rosmarinic acid
Diseases : Amyloidosis
Pharmacological Actions : Neuroprotective Agents
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Neuroprotection comparison of rosmarinic acid and carnosic acid in primary cultures of cerebellar granule neurons.Nov 12, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2018 Nov 13 ;23(11). Epub 2018 Nov 13. PMID: 30428519
Article Published Date : Nov 12, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosic Acid, Rosmarinic acid
Diseases : Alzheimer's Disease, Amyotrophic lateral sclerosis (ALS), Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

O. basilicum and rosmarinic acid on inflammatory and oxidant parameters in sensitized rats which was comparable or even more potent than dexamethasone.Dec 31, 2017

Pubmed Data : Iran J Pharm Res. 2018 ;17(4):1371-1385. PMID: 30568696
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Basil, Rosmarinic acid
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Perilla frutescens and its active compound rosmarinic acid have beneficial effects on cognitive improvement and may help prevent Alzheimer's disease.May 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res Pract. 2016 Jun ;10(3):274-81. Epub 2016 Apr 1. PMID: 27247723
Article Published Date : May 31, 2016
Study Type : Animal Study
Additional Links
Substances : Perilla , Rosmarinic acid
Diseases : Alzheimer's Disease
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor
[+]

Perilla frutescens and rosmarinic acid may play a role in ameliorating allergy diseases.Jan 01, 2011

Pubmed Data : Exp Biol Med (Maywood). 2011 Jan;236(1):99-106. PMID: 21239739
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Perilla , Rosmarinic acid
Diseases : Allergic Rhinitis, Allergic Rhinoconjunctivitis
Pharmacological Actions : Anti-Allergic Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor
Additional Keywords : Plant Extracts
[+]

Prophylactic effect of rosmarinic acid on tracheal responsiveness, white blood cell count and oxidative stress markers in lung lavage of sensitized rats.Jan 16, 2018

Pubmed Data : Pharmacol Rep. 2018 Jan 17 ;70(1):119-125. Epub 2018 Jan 17. PMID: 29355815
Article Published Date : Jan 16, 2018
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Asthma
Pharmacological Actions : Antioxidants
[+]

Purple perilla showed lipid lowering in adipocyte cells and prevented body weight gain in mice.Aug 31, 2018

Pubmed Data : J Food Sci. 2018 Sep ;83(9):2384-2393. Epub 2018 Aug 2. PMID: 30070698
Article Published Date : Aug 31, 2018
Study Type : Animal Study
Additional Links
Substances : Perilla , Rosmarinic acid
Diseases : High Fat Diet, Obesity
Pharmacological Actions : Hypolipidemic
Additional Keywords : Anti-Obesity Agents, Phytotherapy, Plant Extracts
[+]

Rosmarinic acid administration significantly decreased noise-induced hearing loss and the improvement of auditory function.Feb 28, 2018

Pubmed Data : Otol Neurotol. 2018 Mar ;39(3):378-386. PMID: 29424820
Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Hearing Loss: Noise-Induced
Pharmacological Actions : Antioxidants
[+]

Rosmarinic acid alleviates acetaminophen-induced hepatotoxicity.Jul 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2022 Aug ;241:113773. Epub 2022 Jun 24. PMID: 35753269
Article Published Date : Jul 31, 2022
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Acetaminophen (Tylenol) Toxicity , Liver Damage: Drug-Induced, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Nrf2 activation
Problem Substances : Acetaminophen, Paracetamol
[+]

Rosmarinic acid ameliorates acetaminophen-induced acute liver injury.Nov 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2021 Dec ;59(1):1286-1293. PMID: 34517734
Article Published Date : Nov 30, 2021
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Acetaminophen (Tylenol) Toxicity , Liver Damage: Drug-Induced
Pharmacological Actions : Antioxidants, Hepatoprotective
Problem Substances : Acetaminophen
[+]

Rosmarinic acid ameliorates hypoxia/ischemia induced cognitive deficits and promotes remyelination.Apr 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Regen Res. 2020 May ;15(5):894-902. PMID: 31719255
Article Published Date : Apr 30, 2020
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Cerebral Ischemia
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Remyelination
[+]

Rosmarinic acid ameliorates pulmonary ischemia/reperfusion injury.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:860944. Epub 2022 May 11. PMID: 35645792
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Ischemia
Pharmacological Actions : Anti-Apoptotic, Antioxidants
[+]

Rosmarinic acid and sinapic acid on oxidative stress parameters in the cardiac tissue and serum of type 2 diabetic female rats.Nov 21, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2019 Nov 22 ;8(12). Epub 2019 Nov 22. PMID: 31771099
Article Published Date : Nov 21, 2019
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Cardiovascular Diseases, Diabetes: Oxidative Stress, Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Cardioprotective
[+]

Rosmarinic acid and ursolic acid alleviate deficits in cognition, synaptic regulation and adult hippocampal neurogenesis.Jan 30, 2021

Pubmed Data : Phytomedicine. 2021 Jan 31 ;83:153490. Epub 2021 Jan 31. PMID: 33601255
Article Published Date : Jan 30, 2021
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid, Ursolic Acid
Diseases : Alzheimer's Disease
Pharmacological Actions : Neurogenesis, Neuroprotective Agents
[+]

Rosmarinic acid attenuates inflammation in experimentally induced arthritis.Jun 01, 2019

Pubmed Data : Int J Rheum Dis. 2019 Jun 2. Epub 2019 Jun 2. PMID: 31155849
Article Published Date : Jun 01, 2019
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Rosmarinic acid attenuates lipopolysaccharide-induced neuroinflammation and cognitive impairment in rats.Jul 23, 2021

Pubmed Data : J Chem Neuroanat. 2021 Jul 24 ;117:102008. Epub 2021 Jul 24. PMID: 34314849
Article Published Date : Jul 23, 2021
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Rosmarinic acid can effectively reduce enterovirus 71 infection in the early stages of viral infection.Jan 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Virol J. 2019 07 31 ;16(1):94. Epub 2019 Jul 31. PMID: 31366366
Article Published Date : Jan 30, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Enterovirus 71
Pharmacological Actions : Antiviral Agents
[+]

Rosmarinic acid can protect against cardiac dysfunction and fibrosis following myocardial infarction.Aug 18, 2016

Pubmed Data : J Agric Food Chem. 2016 Aug 19. Epub 2016 Aug 19. PMID: 27538767
Article Published Date : Aug 18, 2016
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Myocardial Fibrosis , Myocardial Infarction
Pharmacological Actions : Cardioprotective
[+]

Rosmarinic acid exhibits a lipid-lowering effect.Oct 05, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2021 Oct 6 ;11(10). Epub 2021 Oct 6. PMID: 34680102
Article Published Date : Oct 05, 2021
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : High Fat Diet
Pharmacological Actions : Hypolipidemic
[+]

Rosmarinic acid has an ameliorative effect on colonic inflammation and thus a potential therapeutic role in colitis.Apr 05, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Apr 6 ;7:46252. Epub 2017 Apr 6. PMID: 28383063
Article Published Date : Apr 05, 2017
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-22 Downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, STAT3 Inhibitor
[+]

Rosmarinic acid has antioxidant properties and is an effective hepatoprotective agent.Aug 21, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Folia Morphol (Warsz). 2019 Aug 22. Epub 2019 Aug 22. PMID: 31436305
Article Published Date : Aug 21, 2019
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Liver Injury: Ischemia/reperfusion
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

Rosmarinic acid inhibits DNA glycation and modulates the expression of Akt1 and Akt3 partially in the hippocampus of diabetic rats.Oct 17, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2021 Oct 18 ;11(1):20605. Epub 2021 Oct 18. PMID: 34663861
Article Published Date : Oct 17, 2021
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Hyperglycemia
Pharmacological Actions : Anti-Apoptotic, Anti-Glycation Agents
[+]

Rosmarinic acid inhibits intestinal epithelial apoptosis Via regulation of the Nrf2 pathway in mice.Aug 20, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Aug 21 ;24(17). Epub 2019 Aug 21. PMID: 31438521
Article Published Date : Aug 20, 2019
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : High Fat Diet
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Gastroprotective
[+]

Rosmarinic acid inhibits nicotine-induced C-reactive protein generation.Aug 25, 2018

Pubmed Data : J Cell Physiol. 2018 Aug 26. Epub 2018 Aug 26. PMID: 30146678
Article Published Date : Aug 25, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Atherosclerosis, C-Reactive Protein, Nicotine/Tobacco Toxicity
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Rosmarinic acid inhibits proliferation and invasion of hepatocellular carcinoma cells.Sep 17, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Sep 18 ;120:109443. Epub 2019 Sep 18. PMID: 31541884
Article Published Date : Sep 17, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Rosmarinic acid is effective in reducing blood pressure.Dec 31, 2017

Pubmed Data : Phytomedicine. 2018 Jan 1 ;38:158-165. Epub 2017 Feb 24. PMID: 29425648
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents
[+]

Rosmarinic acid might be a promising therapeutic agent against cardiac fibrosis.Jan 23, 2018

Pubmed Data : Cell Death Dis. 2018 Jan 24 ;9(2):102. Epub 2018 Jan 24. PMID: 29367637
Article Published Date : Jan 23, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Myocardial Fibrosis
Pharmacological Actions : Anti-Fibrotic, Cardioprotective
[+]

Rosmarinic acid might be a promising therapeutic candidate for asthma.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2016 ;21(6). Epub 2016 Jun 13. PMID: 27304950
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Asthma
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Rosmarinic acid mitigates lipopolysaccharide-induced neuroinflammatory responses.Jan 08, 2018

Pubmed Data : Inflammation. 2018 Jan 9. Epub 2018 Jan 9. PMID: 29318480
Article Published Date : Jan 08, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Rosmarinic acid potently detoxifies amylin amyloid and ameliorates diabetic pathology.Aug 12, 2021

Pubmed Data : ACS Pharmacol Transl Sci. 2021 Aug 13 ;4(4):1322-1337. Epub 2021 Jul 21. PMID: 34423269
Article Published Date : Aug 12, 2021
Study Type : Transgenic Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Diabetes: Cognitive Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

Rosmarinic acid protects against lipopolysaccharide-induced cardiac dysfunction.Nov 08, 2022

Pubmed Data : Clin Exp Pharmacol Physiol. 2022 Nov 9. Epub 2022 Nov 9. PMID: 36350269
Article Published Date : Nov 08, 2022
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Cardiomyopathy, Lipopolysaccharide-Induced Toxicity, Sepsis
Pharmacological Actions : Cardioprotective, SIRT1 Activator
[+]

Rosmarinic acid protects mice from imiquimod induced psoriasis-like skin lesions.May 17, 2021

Pubmed Data : Phytother Res. 2021 May 18. Epub 2021 May 18. PMID: 34008239
Article Published Date : May 17, 2021
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Psoriasis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-23 Downregulation
[+]

Rosmarinic acid relieves cisplatin-induced ovary toxicity in female mice via suppression of oxidative stress and inflammation.Jul 10, 2021

Pubmed Data : J Biochem Mol Toxicol. 2021 Jul 11:e22839. Epub 2021 Jul 11. PMID: 34250696
Article Published Date : Jul 10, 2021
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents
[+]

Rosmarinic acid represents a potential therapeutic option against chronic ethanol-induced amnesia.Jun 30, 2016

Pubmed Data : Nutr Neurosci. 2016 Jul 1:1-8. Epub 2016 Jul 1. PMID: 27367870
Article Published Date : Jun 30, 2016
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Alcohol Toxicity , Amnesia: Drug-Induced
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Dose Response, Natural Substances Versus Drugs
Problem Substances : Donepezil (trade name Aricept)
[+]

Rosmarinic acid represses colitis-associated colon cancer.May 29, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neoplasia. 2021 May 30 ;23(6):561-573. Epub 2021 May 30. PMID: 34077834
Article Published Date : May 29, 2021
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Chemopreventive, Chemotherapeutic, NF-kappaB Inhibitor, STAT3 Inhibitor
[+]

Rosmarinic acid reverses non-small cell lung cancer cisplatin resistance by activating the MAPK signaling pathway.Jan 26, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytother Res. 2020 Jan 27. Epub 2020 Jan 27. PMID: 31985119
Article Published Date : Jan 26, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Lung Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Multidrug Resistance Gene Modulators, P21 Activation, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Chemotherapeutic Synergy: Cisplatin
[+]

Rosmarinic acid suppresses abdominal aortic aneurysm progression in apolipoprotein E-deficient mice.Nov 04, 2021

Pubmed Data : Planta Med. 2021 Nov 5. Epub 2021 Nov 5. PMID: 34741296
Article Published Date : Nov 04, 2021
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Aneurysm
Pharmacological Actions : Anti-Apoptotic, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Rosmarinic acid, major phenolic constituent of Greek sage herbal tea, modulates rat intestinal SGLT1 levels with effects on blood glucose.Mar 24, 2011

Pubmed Data : Mol Nutr Food Res. 2011 Mar 24. Epub 2011 Mar 24. PMID: 21433280
Article Published Date : Mar 24, 2011
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid, Salvia fruticosa
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, SGLT1 inducer
[+]

Salvia officinalis and its principal constituent rosmarinic acid represent a potential therapeutic option against diabetic memory impairment.Apr 21, 2016

Pubmed Data : Neurosci Lett. 2016 Apr 22 ;622:72-77. Epub 2016 Apr 22. PMID: 27113201
Article Published Date : Apr 21, 2016
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid, Sage
Diseases : Diabetes: Memory Problems
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Superoxide Dismutase Up-regulation
[+]

Salvia officinalis, rosmarinic and caffeic acids attenuate neuropathic pain and improve function recovery after sciatic nerve chronic constriction.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:1702378. Epub 2019 Jun 24. PMID: 31341489
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Carnosic Acid, Rosmarinic acid, Sage
Diseases : Neuropathic Pain, Sciatic Nerve Crush Injury
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

The effect of rosmarinic acid on the prevention of myringosclerosis.Jul 22, 2019

Pubmed Data : Int J Pediatr Otorhinolaryngol. 2019 Jul 23 ;126:109597. Epub 2019 Jul 23. PMID: 31351349
Article Published Date : Jul 22, 2019
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Myringosclerosis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

The protective effects of rosmarinic acid on ethanol-induced gastritis.May 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Res Pharm Sci. 2021 Jun ;16(3):305-314. Epub 2021 May 12. PMID: 34221064
Article Published Date : May 31, 2021
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Alcohol Toxicity , Gastritis
Pharmacological Actions : Gastrointestinal Agents, Gastroprotective
[+]

These results demonstrate the therapeutic activity of rosmarinic acid against the oxaliplatin-induced mitochondrial dysfunction and neuroinflammation.Feb 08, 2018

Pubmed Data : Mol Neurobiol. 2018 Feb 9. Epub 2018 Feb 9. PMID: 29427084
Article Published Date : Feb 08, 2018
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Chemotherapy-Induced Toxicity: Oxaliplatin
Pharmacological Actions : Chemoprotective Agents
[+]

Toxicological evaluation and hepatoprotective efficacy of rosmarinic acid-rich extract from Ocimum basilicum.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:6676998. Epub 2021 Jan 31. PMID: 33603821
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Basil, Rosmarinic acid
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Hepatoprotective
[+]

Rosmarinic acid-induced apoptosis and cell cycle arrest in triple-negative breast cancer cells.Jul 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur J Pharmacol. 2020 Aug 1:173419. Epub 2020 Aug 1. PMID: 32750370
Article Published Date : Jul 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

A review of the anticancer effects of rosemary extract and rosemary extract polyphenols.Nov 16, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2016 Nov 17 ;8(11). Epub 2016 Nov 17. PMID: 27869665
Article Published Date : Nov 16, 2016
Study Type : Review
Additional Links
Substances : Carnosic Acid, Polyphenols, Rosemary, Rosmarinic acid
Diseases : Cancers: All
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Antiproliferative
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Antitumor activity of rosmarinic acid-loaded silk fibroin nanoparticles on HeLa and MCF-7 cells.Sep 17, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Polymers (Basel). 2021 Sep 18 ;13(18). Epub 2021 Sep 18. PMID: 34578069
Article Published Date : Sep 17, 2021
Study Type : In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Breast Cancer, Cervical Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Attenuation of neuroinflammation in microglia cells by extracts with high content of rosmarinic acid from in vitro cultured Melissa officinalis L. cells.Jul 28, 2022

Pubmed Data : J Pharm Biomed Anal. 2022 Jul 29 ;220:114969. Epub 2022 Jul 29. PMID: 35961210
Article Published Date : Jul 28, 2022
Study Type : In Vitro Study
Additional Links
Substances : Lemongrass, Rosmarinic acid
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor
[+]

Bidirect effects from cisplatin combine with rosmarinic acid (RA) or hot water extracts of Glechoma hederacea (HWG) on renal cancer cells.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin Med. 2020 ;15:77. Epub 2020 Jul 29. PMID: 32760434
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Kidney Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Cell cycle arrest
Additional Keywords : Chemotherapeutic Synergy: Cisplatin
[+]

Candidate anti-COVID-19 medicinal plants from Ethiopia.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:6622410. Epub 2021 Jun 4. PMID: 34221083
Article Published Date : Dec 31, 2020
Study Type : Review
Additional Links
Substances : Allicin, Almond, Apigenin, Artemisinin, Curcumin, EGCG (Epigallocatechin gallate), Gingerol , Hesperidin, Kaempferol, Nobiletin , Oleanolic acid, Piperine, Resveratrol, Rosmarinic acid, Tangeretin , Ursolic Acid
Diseases : Coronavirus Infection
Pharmacological Actions : Antiviral Agents
[+]

Discovery of natural compounds as nonpeptidyl inhibitors is a significant transition towards feasible drug development for neurodegenerative disorders.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2015 ;2015:379817. Epub 2015 May 4. PMID: 26064904
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Curcumin, Rosmarinic acid
Diseases : Alzheimer's Disease, Amyotrophic lateral sclerosis (ALS), Huntington Disease, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Nonpeptidyl Inhibitors
[+]

Effect of dietary polyphenols on osteoarthritis-molecular mechanisms. Mar 15, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Life (Basel). 2022 Mar 16 ;12(3). Epub 2022 Mar 16. PMID: 35330187
Article Published Date : Mar 15, 2022
Study Type : Review
Additional Links
Substances : Curcumin, EGCG (Epigallocatechin gallate), Frankincense, Genistein, Pine Bark Extract, Polyphenols, Quercetin, Resveratrol, Rosmarinic acid
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

Effects of rosmarinic acid, carnosic acid, rosmanol, carnosol, and ursolic acid on the pathogenesis of respiratory diseases.Dec 22, 2022

Pubmed Data : Biofactors. 2022 Dec 23. Epub 2022 Dec 23. PMID: 36564953
Article Published Date : Dec 22, 2022
Study Type : In Vitro Study
Additional Links
Substances : Carnosic Acid, Carnosol, Rosmarinic acid, Ursolic Acid
Diseases : Respiratory Diseases
Pharmacological Actions : Anti-Inflammatory Agents, interleukin-13 down-regulation, Interleukin-4 downregulation, Interleukin-5 downregulation
[+]

Natural anti-inflammatory compounds as treatment candidates in Alzheimer’s disease. Jul 29, 2020

Pubmed Data : Curr Med Chem. 2020 Jul 30. Epub 2020 Jul 30. PMID: 32744957
Article Published Date : Jul 29, 2020
Study Type : Review
Additional Links
Substances : Berberine, Curcumin, Genistein, Quercetin, Resveratrol, Rosmarinic acid
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Phytochemicals and micronutrients may enhance efficacy of doxycycline in combating all the morphological forms of studied Borrelia sp.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Biol Sci. 2016 ;12(9):1093-103. Epub 2016 Jul 22. PMID: 27570483
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Baicalein, Iodine, Luteolin, Rosmarinic acid, Vitamin C, Vitamin D
Diseases : Lyme Borreliosis, Lyme Disease
Pharmacological Actions : Antimicrobial
Additional Keywords : Natural Substance/Drug Synergy
[+]

Polyphenol antioxidants have properties to treat neurodegenerative diseases.Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Basic Clin Neurosci. 2016 Apr ;7(2):81-90. PMID: 27303602
Article Published Date : Mar 31, 2016
Study Type : Review
Additional Links
Substances : Allicin, Carnosic Acid, Curcumin, EGCG (Epigallocatechin gallate), Isothiocyanate, Quercetin, Resveratrol, Rosmarinic acid, Sulforaphane
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Polyphenols were capable of inhibiting the formation of both total fluorescent AGEs and nonfluorescent carboxymethyllysine (CML).Sep 30, 2014

Pubmed Data : Food Funct. 2014 Oct ;5(10):2656-61. Epub 2014 Sep 11. PMID: 25208810
Article Published Date : Sep 30, 2014
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid, Epicatechin, Naringenin , Phloretin, Polyphenols, Rosmarinic acid
Diseases : Advanced Glycation End products (AGE), Oxidative Stress
Pharmacological Actions : Antioxidants, Cytoprotective
[+]

Rosmarinic acid and blue light combination treatment inhibits head and neck squamous cell carcinoma.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anticancer Res. 2020 Feb ;40(2):751-758. PMID: 32014917
Article Published Date : Jan 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Head and Neck Cancer
Therapeutic Actions : Light Therapy: Colored
Pharmacological Actions : Antiproliferative
[+]

Rosmarinic acid and carnosic acid could prevent the formation of advanced glycation end-products in vitro. Apr 14, 2017

Pubmed Data : Food Chem. 2017 Apr 15 ;221:1057-1061. Epub 2016 Nov 11. PMID: 27979058
Article Published Date : Apr 14, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carnosic Acid, Rosemary, Rosmarinic acid
Diseases : Advanced Glycation End products (AGE)
Pharmacological Actions : Anti-Glycation Agents
Additional Keywords : Plant Extracts
[+]

Rosmarinic acid as a candidate in a phenotypic profiling cardio-/cytotoxicity cell model induced by doxorubicin.Feb 13, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Feb 14 ;25(4). Epub 2020 Feb 14. PMID: 32075047
Article Published Date : Feb 13, 2020
Study Type : In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Cardioprotective, Chemoprotective Agents
[+]

Rosmarinic acid could be potential therapeutic agent against metastasis of colorectal cancer.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:68. Epub 2018 Feb 5. PMID: 29459827
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Colorectal Cancer
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Rosmarinic acid could be used for preventing UVB induced photodamage.Oct 03, 2021

Pubmed Data : Photochem Photobiol. 2021 Oct 4. Epub 2021 Oct 4. PMID: 34608633
Article Published Date : Oct 03, 2021
Study Type : In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Ultraviolet Radiation Induced Damage
Pharmacological Actions : Antioxidants, Photoprotective
[+]

Rosmarinic acid exerts an antagonistic effect on vascular calcification.Mar 12, 2019

Pubmed Data : Free Radic Res. 2019 Mar 13:1-11. Epub 2019 Mar 13. PMID: 30864863
Article Published Date : Mar 12, 2019
Study Type : In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Vascular Calcification
Pharmacological Actions : Antioxidants, Nrf2 activation
[+]

Rosmarinic acid induces proliferation suppression of hepatoma cells associated with NF-κB signaling pathway.Apr 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2021 May 1 ;22(5):1623-1632. Epub 2021 May 1. PMID: 34048194
Article Published Date : Apr 30, 2021
Study Type : In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Liver Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic, Antiproliferative , Apoptotic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor
[+]

Rosmarinic acid is a novel inhibitor for Hepatitis B virus replication.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2018 ;13(5):e0197664. Epub 2018 May 21. PMID: 29782545
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Hepatitis B
Pharmacological Actions : Antiviral Agents
Additional Keywords : Natural Substance/Drug Synergy
[+]

Rosmarinic acid may help preserve adipose tissue-derived stem cells survival after they are transplanted into ischemic organs.Nov 30, 2019

Pubmed Data : Prev Nutr Food Sci. 2019 Dec ;24(4):449-455. Epub 2019 Dec 31. PMID: 31915641
Article Published Date : Nov 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Rosmarinic acid
Pharmacological Actions : Cytoprotective
Additional Keywords : Mesenchymal Stem Cells
[+]

Rosmarinic acid might be used as an adjuvant therapeutic factor in breast cancer treatment.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ginekol Pol. 2018 ;89(10):541-545. PMID: 30393841
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Breast Cancer
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Gene Expression Regulation
[+]

Rosmarinic acid protects on rat bone marrow mesenchymal stem cells from hydrogen peroxide-induced apoptosis.Jan 27, 2018

Pubmed Data : J Asian Nat Prod Res. 2018 Jan 28:1-11. Epub 2018 Jan 28. PMID: 29376419
Article Published Date : Jan 27, 2018
Study Type : In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Hydrogen Peroxide Induced Toxicity
Pharmacological Actions : Anti-Apoptotic
[+]

Rosmarinic acid rich fraction may be further developed as an inhalation agent for the prevention of lung inflammation and cancer metastasis induced by PM exposure.Jul 22, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2021 Jul 23 ;11(8). Epub 2021 Jul 23. PMID: 34439757
Article Published Date : Jul 22, 2021
Study Type : In Vitro Study
Additional Links
Substances : Perilla , Rosmarinic acid
Diseases : Air Pollution Linked Toxicity, Lung Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic, Antioxidants, Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords : Risk Reduction
[+]

Rosmarinus officinalis L.: an update review of its phytochemistry and biological activity.Mar 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Future Sci OA. 2018 Apr ;4(4):FSO283. Epub 2018 Feb 1. PMID: 29682318
Article Published Date : Mar 31, 2018
Study Type : Review
Additional Links
Substances : Carnosic Acid, Carnosol, Rosemary, Rosmarinic acid
Diseases : Alzheimer's Disease, Depression, Inflammation, Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Analgesics, Anti-Bacterial Agents, Anti-Infective Agents, Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Tanshinone IIA-loaded micelles functionalized with rosmarinic acid: a novel Synergistic anti-inflammatory strategy for treatment of atherosclerosis.May 13, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharm Sci. 2022 May 14. Epub 2022 May 14. PMID: 35580692
Article Published Date : May 13, 2022
Study Type : In Vitro Study
Additional Links
Substances : Rosmarinic acid, Tanshinone IIA
Diseases : Atherosclerosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
Additional Keywords : Natural Substance Synergy
[+]

The antibacterial mechanism of perilla rosmarinic acid.Sep 06, 2021

Pubmed Data : Biotechnol Appl Biochem. 2021 Sep 7. Epub 2021 Sep 7. PMID: 34490944
Article Published Date : Sep 06, 2021
Study Type : In Vitro Study
Additional Links
Substances : Perilla , Rosmarinic acid
Diseases : Bacillus subtilis infections, Escherichia coli Infections, Salmonella Infections, Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents
[+]

The current study shows an effect of rosmarinic acid to increase muscle glucose uptake and AMPK phosphorylation.Oct 06, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2017 Oct 7 ;22(10). Epub 2017 Oct 7. PMID: 28991159
Article Published Date : Oct 06, 2017
Study Type : Review
Additional Links
Substances : Rosemary, Rosmarinic acid
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
[+]

The cytotoxic concentration of rosmarinic acid can potentiate the effects of MG132 in hepatocellular carcinoma treatment.Dec 25, 2019

Pubmed Data : Hum Exp Toxicol. 2019 Dec 26:960327119896614. Epub 2019 Dec 26. PMID: 31876192
Article Published Date : Dec 25, 2019
Study Type : In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Natural Substance/Drug Synergy
[+]

The data suggest potential usefulness of rosmarinic acid as a complementary agent supporting chemotherapy in cancer treatment.Aug 08, 2018

Pubmed Data : Biomed Pharmacother. 2018 Aug 9 ;107:397-407. Epub 2018 Aug 9. PMID: 30099344
Article Published Date : Aug 08, 2018
Study Type : In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Gastric Cancer
Pharmacological Actions : Chemotherapeutic, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

These data suggest that daily use of rosmarinic acid-enriched dietary supplements can contribute to tumor prevention.Jan 01, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2022 10 2 ;12(10). Epub 2022 Oct 2. PMID: 36291619
Article Published Date : Jan 01, 2022
Study Type : Review
Additional Links
Substances : Rosmarinic acid
Diseases : Cancers: All
Pharmacological Actions : Antioxidants, Chemopreventive
[+]

These findings suggest that Melissa officinalis and its constituent rosmarinic acid possess anti-EV71 activities.Sep 24, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Sep 25 ;7(1):12264. Epub 2017 Sep 25. PMID: 28947773
Article Published Date : Sep 24, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lemon Balm, Rosmarinic acid
Diseases : Enterovirus: Type 71
Pharmacological Actions : Antiviral Agents
[+]

These findings suggest that P. frutescens var. japonica and rosmarinic acid could prevent the progression of neurodegenerative diseases.Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomol Ther (Seoul). 2016 May 1 ;24(3):338-45. PMID: 27133263
Article Published Date : Apr 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Perilla , Rosmarinic acid
Diseases : Brain: Oxidative Stress, Hydrogen Peroxide Induced Toxicity, Neurodegenerative Diseases
Pharmacological Actions : Antioxidants, Cyclooxygenase 2 Inhibitors, Neuroprotective Agents
[+]

These results suggest the possibility that rosmarinic acid can enhance neural plasticity.Jun 16, 2016

Pubmed Data : Biochem Biophys Res Commun. 2016 Jun 17 ;475(1):44-50. Epub 2016 May 6. PMID: 27163641
Article Published Date : Jun 16, 2016
Study Type : In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Memory Disorders: Drug-Induced
Pharmacological Actions : Neuroplasticity enhancement
[+]

This evidence shows a promising therapeutic role for rosmarinic acid in inflammatory status.Apr 28, 2020

Pubmed Data : Mol Biol Rep. 2020 Apr 29. Epub 2020 Apr 29. PMID: 32350743
Article Published Date : Apr 28, 2020
Study Type : In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

This study clarified that mangiferin, rosmarinic acid and salviaflaside were considered as the anti-insomnia components of P. vulgaris.Oct 27, 2021

Pubmed Data : J Ethnopharmacol. 2021 Oct 28 ;279:114373. Epub 2021 Jun 26. PMID: 34181959
Article Published Date : Oct 27, 2021
Study Type : Review
Additional Links
Substances : Mangiferin, Prunella vulgaris, Rosmarinic acid
Diseases : Insomnia

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