Rubia Cordifolia

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58 Diseases Researched for Rubia Cordifolia
NameACCKFocus
Oxidative Stress57Locked
Alzheimer's Disease25Locked
Inflammation45Locked
Lipid Peroxidation35Locked
Liver Cancer23Locked
Ulcerative Colitis23Locked
Aspirin-Induced Toxicity 12Locked
Brain Ischemia12Locked
Cancers: All22Locked
Candida Infection 22Locked
Cervical Cancer12Locked
Chemotherapy-Induced Toxicity12Locked
Chemotherapy-Induced Toxicity: Cyclophosphamide12Locked
Chemotherapy-Induced Toxicity: Cisplatin12Locked
Crohn's Disease12Locked
DNA damage12Locked
Depression12Locked
Diabetes Mellitus: Type 1: Prevention12Locked
Diabetic Nephropathy12Locked
Diarrhea12Locked
Gastric Ulcer12Locked
Histamine: Elevated12Locked
Hyperalgesia12Locked
IgE-Mediated Hypersensitivity12Locked
Inflammatory Bowel Diseases12Locked
Iron Overload12Locked
Kidney Damage12Locked
Kidney Stones12Locked
Lipopolysaccharide-Induced Toxicity12Locked
Memory Disorders12Locked
Polycystic Ovary Syndrome12Locked
Psoriasis12Locked
Radiation Induced Illness12Locked
Rheumatoid Arthritis12Locked
Salmonella Infections22Locked
Seizures12Locked
Staphylococcus aureus infection22Locked
Aging11Locked
Arthritis11Locked
Atopic Dermatitis11Locked
Bacillus subtilis infections11Locked
Blood Diseases11Locked
Breast Cancer11Locked
Candida Albicans11Locked
Colon Cancer11Locked
Dementia11Locked
Diabetic Neuropathy11Locked
Escherichia coli Infections11Locked
Lung Cancer11Locked
Myocardial Infarction11Locked
Myocardial Ischemia11Locked
Nasopharyngeal Cancer11Locked
Orofacial Dyskinesia11Locked
Pseudomonas aeruginosa11Locked
Rotavirus Infections11Locked
Skin Cancer11Locked
Skin Diseases11Locked
Vitiligo11Locked
40 Pharmacological Actions Researched for Rubia Cordifolia
NameACCKFocus
Anti-Inflammatory Agents1319Locked
Antioxidants1219Locked
Neuroprotective Agents48Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor47Locked
Superoxide Dismutase Up-regulation36Locked
Antiproliferative 45Locked
Apoptotic45Locked
Interleukin-1 beta downregulation35Locked
Antineoplastic Agents34Locked
Gastrointestinal Agents24Locked
Immunomodulatory24Locked
Renoprotective24Locked
Analgesics23Locked
Anti-Apoptotic33Locked
Anti-Bacterial Agents33Locked
Interleukin-6 Downregulation33Locked
Anticonvulsants12Locked
Antidepressive Agents12Locked
Antidiarrheals12Locked
Antimicrobial22Locked
Cardioprotective12Locked
Chemopreventive12Locked
Chemotherapeutic22Locked
Gastroprotective12Locked
Histamine down-regulation12Locked
Hypoglycemic Agents12Locked
NF-kappaB Inhibitor12Locked
Nitric Oxide Inhibitor12Locked
Nootropic Agents12Locked
Postaglandin PGE2 downregulation 12Locked
Radioprotective12Locked
Anti-Angiogenic11Locked
Anti-thrombotic11Locked
Antifungal Agents11Locked
Antimutagenic Agents11Locked
Antiviral Agents11Locked
Interleukin-17 downregulation11Locked
Interleukin-8 downregulation11Locked
Topoisomerase I inhibitor11Locked
Topoisomerase II Inhibitor11Locked

View the Evidence:
51 Abstracts with Rubia Cordifolia Research

[+]

Neuroinflammation inhibition and neuroprotective effects of purpurin.Oct 31, 2024

Pubmed Data : Phytother Res. 2024 Nov ;38(11):5474-5489. Epub 2024 Oct 1. PMID: 39351804
Article Published Date : Oct 31, 2024
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Ameliorative effect of methanol extract of Rubia cordifolia in N-nitrosodiethylamine-induced hepatocellular carcinoma.Feb 29, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2012 Mar ;50(3):376-83. Epub 2011 Dec 1. PMID: 22133091
Article Published Date : Feb 29, 2012
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Lipid Peroxidation, Liver Cancer
Pharmacological Actions : Antioxidants, Chemopreventive
Additional Keywords : Plant Extracts
[+]

Anticonvulsant and behavioral actions of triterpene isolated from Rubia cordifolia.Jun 30, 2000

Pubmed Data : Indian J Exp Biol. 2000 Jul ;38(7):675-80. PMID: 11215310
Article Published Date : Jun 30, 2000
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Seizures
Pharmacological Actions : Anticonvulsants
[+]

Antihyperglycemic, antistress and nootropic activity of roots of Rubia cordifolia.Nov 30, 2006

Pubmed Data : Indian J Exp Biol. 2006 Dec ;44(12):987-92. PMID: 17176672
Article Published Date : Nov 30, 2006
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Memory Disorders
Pharmacological Actions : Hypoglycemic Agents, Nootropic Agents
Additional Keywords : Plant Extracts
[+]

Characterization of Rubia cordifolia L. root extract and its evaluation of cardioprotective effect in Wistar rat model.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Pharmacol. 2018 ;50(1):12-21. PMID: 29861523
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide, Lipid Peroxidation
Pharmacological Actions : Antioxidants, Cardioprotective, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
[+]

Chinese herbal extracts of Rubia cordifolia and Dianthus superbus suppress IgE production and prevent peanut-induced anaphylaxis.Sep 29, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin Med. 2011 Sep 30 ;6:35. Epub 2011 Sep 30. PMID: 21961957
Article Published Date : Sep 29, 2011
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Histamine: Elevated, IgE-Mediated Hypersensitivity
Pharmacological Actions : Histamine down-regulation, Immunomodulatory
[+]

Cornuside ameliorates diabetic nephropathy possibly by regulating angiogenesis and MAPK signaling.May 27, 2025

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Tohoku J Exp Med. 2025 May 28 ;266(1):87-95. Epub 2024 Oct 24. PMID: 39443135
Article Published Date : May 27, 2025
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Diabetic Nephropathy
Pharmacological Actions : Renoprotective
[+]

Gastroprotective effect of Rubia cordifolia on aspirin plus pylorus-ligated ulcer.Dec 31, 2010

Pubmed Data : Evid Based Complement Alternat Med. 2011 ;2011:541624. Epub 2011 Feb 24. PMID: 21423635
Article Published Date : Dec 31, 2010
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Aspirin-Induced Toxicity , Gastric Ulcer
Pharmacological Actions : Gastrointestinal Agents, Gastroprotective
Problem Substances : Aspirin
[+]

Mollugin has an anti-cancer therapeutic effect by inhibiting TNF-α-induced NF-κB activation.Jul 25, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2017 Jul 26 ;18(8). Epub 2017 Jul 26. PMID: 28933726
Article Published Date : Jul 25, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Cervical Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative , Apoptotic, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Protective activity of purpurin against d-galactosamine and lipopolysaccharide-induced hepatorenal injury.Sep 30, 2022

Pubmed Data : J Biochem Mol Toxicol. 2022 Oct ;36(10):e23168. Epub 2022 Jul 15. PMID: 35838105
Article Published Date : Sep 30, 2022
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Inflammation, Iron Overload, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Antioxidants, Superoxide Dismutase Up-regulation
[+]

Protective effect of hydroalcoholic root extract of Rubia cordifolia in indomethacin-induced enterocolitis.Feb 28, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Pharm Sci. 2011 Mar ;73(2):250-3. PMID: 22303076
Article Published Date : Feb 28, 2011
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Crohn's Disease, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents
Problem Substances : Indomethacin
[+]

Purpurin ameliorated neuropathic allodynia and hyperalgesia.Sep 04, 2024

Pubmed Data : Eur J Pharmacol. 2024 Sep 5 ;978:176749. Epub 2024 Jun 17. PMID: 38897444
Article Published Date : Sep 04, 2024
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Diabetes Mellitus: Type 1: Prevention, Hyperalgesia, Oxidative Stress
Pharmacological Actions : Analgesics
[+]

Purpurin exerted antidepressant-like effects on behavior and stress axis reactivity: evidence of serotonergic engagement.Feb 29, 2020

Pubmed Data : Psychopharmacology (Berl). 2020 Mar ;237(3):887-899. Epub 2020 Jan 3. PMID: 31900524
Article Published Date : Feb 29, 2020
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]

Purpurin modulates Tau-derived VQIVYK fibrillization and ameliorates Alzheimer's disease-like symptoms in animal model.Jun 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Mol Life Sci. 2020 Jul ;77(14):2795-2813. Epub 2019 Sep 27. PMID: 31562564
Article Published Date : Jun 30, 2020
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Rubia cordifolia ameliorates cisplatin-induced nephrotoxicity in mice.Jul 01, 2008

Pubmed Data : J Cancer Res Ther. 2008 Jul-Sep;4(3):111-5. PMID: 18923202
Article Published Date : Jul 01, 2008
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Chemotherapy-Induced Toxicity, Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Antineoplastic Agents
Additional Keywords : Plant Extracts
[+]

Rubia cordifolia has a protective effect against ethylene glycol induced kidney stones in rats.Apr 01, 2010

Pubmed Data : Food Chem Toxicol. 2010 Apr;48(4):1013-8. Epub 2010 Jan 15. PMID: 20079795
Article Published Date : Apr 01, 2010
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Kidney Stones
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Rubia cordifolia has radioprotective properties.Jul 01, 2007

Pubmed Data : Indian J Exp Biol. 2007 Jul;45(7):620-5. PMID: 17821858
Article Published Date : Jul 01, 2007
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia
Diseases : DNA damage, Radiation Induced Illness
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Radioprotective
Additional Keywords : Plant Extracts
[+]

Rubia cordifolia Linn.: Isolation, molecular docking and BRAC1/PKD1 gene targeting for polycystic ovary syndrome in rats.May 31, 2025

Pubmed Data : J Reprod Immunol. 2025 Jun ;169:104532. Epub 2025 Apr 8. PMID: 40215836
Article Published Date : May 31, 2025
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Polycystic Ovary Syndrome
Additional Keywords : Anti-Obesity Agents, Plant Extracts
[+]

Rubia cordifolia may have a therapeutic role in psoriasis treatment. Mar 01, 2004

Pubmed Data : Am J Hosp Palliat Care. 2004 Mar-Apr;21(2):95-104. PMID: 19960426
Article Published Date : Mar 01, 2004
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Psoriasis
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Rubia cordifolia, Fagonia cretica linn and Tinospora cordifolia exert neuroprotection.Aug 12, 2004

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2004 Aug 13 ;4:11. Epub 2004 Aug 13. PMID: 15310392
Article Published Date : Aug 12, 2004
Study Type : Animal Study
Additional Links
Substances : Guduchi , Rubia Cordifolia
Diseases : Brain Ischemia
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
Additional Keywords : Phytotherapy
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The potential mechanism of co-administration of Scutellaria baicalensis Georgi and Rubia cordifolia L ameliorating ulcerative colitis.Sep 14, 2025

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharm Biomed Anal. 2025 Sep 15 ;263:116948. Epub 2025 May 5. PMID: 40344969
Article Published Date : Sep 14, 2025
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia, Skullcap: Chinese
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents
Additional Keywords : Plant Extracts
[+]

The protective effect of Rubia cordifolia against lead nitrate-induced immune response impairment and kidney oxidative damage.Jun 30, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Pharmacol. 2011 Jul ;43(4):441-4. PMID: 21845002
Article Published Date : Jun 30, 2011
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Kidney Damage, Oxidative Stress
Pharmacological Actions : Antioxidants, Immunomodulatory, Renoprotective
[+]

The study validated the traditional use of Rubia cordifolia as a valuable natural remedy for the treatment of diarrhea.Jan 04, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2017 Jan 5 ;17(1):20. Epub 2017 Jan 5. PMID: 28056930
Article Published Date : Jan 04, 2017
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Diarrhea
Pharmacological Actions : Anti-Inflammatory Agents, Antidiarrheals, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The underling mechanisms exploration of Rubia cordifolia L. extract against rheumatoid arthritis.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2023 ;17:439-457. Epub 2023 Feb 11. PMID: 36818604
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Analysis of active components and molecular mechanism of action of Rubia cordifolia L. in the treatment of nasopharyngeal carcinoma.May 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Heliyon. 2023 Jun ;9(6):e17078. Epub 2023 Jun 8. PMID: 37484327
Article Published Date : May 31, 2023
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Nasopharyngeal Cancer
Pharmacological Actions : Anti-Apoptotic, Antiproliferative
[+]

Anthraquinones from the aerial parts of Rubia cordifolia with their NO inhibitory and antibacterial activities.Mar 06, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2022 Mar 7 ;27(5). Epub 2022 Mar 7. PMID: 35268830
Article Published Date : Mar 06, 2022
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Escherichia coli Infections, Pseudomonas aeruginosa, Salmonella Infections, Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Plant Extracts
[+]

Anti-thrombotic and pro-angiogenic effects of Rubia cordifolia extracts.Nov 06, 2017

Pubmed Data : J Ethnopharmacol. 2017 Nov 7 ;219:152-160. Epub 2017 Nov 7. PMID: 29126989
Article Published Date : Nov 06, 2017
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Blood Diseases
Pharmacological Actions : Anti-Angiogenic, Anti-thrombotic
[+]

Characterization and antimicrobial evaluation of anthraquinones and triterpenes from Rubia cordifolia.Oct 31, 2023

Pubmed Data : J Asian Nat Prod Res. 2023 Nov ;25(11):1110-1116. Epub 2023 Apr 3. PMID: 37010931
Article Published Date : Oct 31, 2023
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Staphylococcus aureus infection
Pharmacological Actions : Antimicrobial
[+]

Constituents with DNA topoisomerases I and II inhibitory activity and cytotoxicity from the roots of Rubia cordifolia.Dec 31, 2011

Pubmed Data : Planta Med. 2012 Jan ;78(2):177-81. Epub 2011 Oct 6. PMID: 21979931
Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Cancers: All
Pharmacological Actions : Topoisomerase I inhibitor, Topoisomerase II Inhibitor
Additional Keywords : Plant Extracts
[+]

Evaluation of analgesic and anti-inflammatory activities of Rubia cordifolia L. by spectrum-effect relationships,Jul 14, 2018

Pubmed Data : J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Jul 15 ;1090:73-80. Epub 2018 May 17. PMID: 29793098
Article Published Date : Jul 14, 2018
Study Type : Review
Additional Links
Substances : Rubia Cordifolia
Diseases : Arthritis
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

In vitro antiviral Activity of Rubia cordifolia aerial part extract against rotavirus.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2016 ;7:308. Epub 2016 Sep 13. PMID: 27679574
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Rotavirus Infections
Pharmacological Actions : Antiviral Agents
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Lucidin from Rubia cordifolia outperforms FDA-approved lapatinib as a potential multitargeted candidate for breast cancer signalling proteins.Jan 08, 2025

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2025 Jan 9 ;18(1). Epub 2025 Jan 9. PMID: 39861131
Article Published Date : Jan 08, 2025
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Breast Cancer
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Madder (Rubia cordifolia L.) alleviates myocardial ischemia-reperfusion injury.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mediators Inflamm. 2023 ;2023:5015039. Epub 2023 Feb 23. PMID: 36875688
Article Published Date : Dec 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Inflammation, Myocardial Infarction, Myocardial Ischemia
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents
[+]

Modulatory role of alizarin from Rubia cordifolia L. against genotoxicity of mutagens.Dec 31, 2009

Pubmed Data : Food Chem Toxicol. 2010 Jan ;48(1):320-5. Epub 2009 Oct 21. PMID: 19852997
Article Published Date : Dec 31, 2009
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Skin Cancer, Skin Diseases
Pharmacological Actions : Antimutagenic Agents
[+]

Novel antifungal activity of purpurin against Candida species in vitro.Oct 31, 2010

Pubmed Data : Med Mycol. 2010 Nov ;48(7):904-11. PMID: 20392152
Article Published Date : Oct 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Candida Infection
Pharmacological Actions : Antifungal Agents
[+]

Phytochemical characterization, antioxidant and anti-proliferative properties of Rubia cordifolia.May 19, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2022 May 20 ;11(5). Epub 2022 May 20. PMID: 35624869
Article Published Date : May 19, 2022
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Liver Cancer, Oxidative Stress
Pharmacological Actions : Antioxidants, Antiproliferative
[+]

Protective effect of Rubia cordifolia on reserpine-induced orofacial dyskinesia.Dec 31, 2011

Pubmed Data : Nat Prod Res. 2012 ;26(22):2159-61. Epub 2011 Nov 18. PMID: 22092272
Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Lipid Peroxidation, Orofacial Dyskinesia
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Purpurin ameliorates D-galactose-induced aging phenotypes in mouse hippocampus by reducing inflammatory responses.Jun 30, 2023

Pubmed Data : Neurochem Int. 2023 Jul ;167:105552. Epub 2023 May 23. PMID: 37230197
Article Published Date : Jun 30, 2023
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Aging, Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Purpurin as a promising anticancer agent: A review of preclinical evidence.Dec 21, 2025

Pubmed Data : Fitoterapia. 2025 Dec 22:107052. Epub 2025 Dec 22. PMID: 41443512
Article Published Date : Dec 21, 2025
Study Type : Review
Additional Links
Substances : Rubia Cordifolia
Diseases : Cancers: All
Pharmacological Actions : Chemotherapeutic
[+]

Purpurin binding interacts with LHPP protein that inhibits PI3K/AKT phosphorylation and induces apoptosis in colon cancer cells HCT-116.Feb 28, 2021

Pubmed Data : J Biochem Mol Toxicol. 2021 Mar ;35(3):e22665. Epub 2020 Dec 28. PMID: 33368780
Article Published Date : Feb 28, 2021
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Colon Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic
[+]

Purpurin suppresses atopic dermatitis via TNF-α/IFN-γ-induced inflammation in HaCaT cells.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Immunopathol Pharmacol. 2022 ;36:3946320221111135. PMID: 35794850
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Atopic Dermatitis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Purpurin suppresses Candida albicans biofilm formation and hyphal development.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2012 ;7(11):e50866. Epub 2012 Nov 30. PMID: 23226409
Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Candida Albicans
Pharmacological Actions : Antimicrobial
[+]

Purpurin suppresses Salmonella invasion of host cells.Feb 05, 2025

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2025 Feb 6 ;15(1):4507. Epub 2025 Feb 6. PMID: 39915561
Article Published Date : Feb 05, 2025
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Salmonella Infections
Pharmacological Actions : Anti-Bacterial Agents
[+]

Purpurin triggers caspase-independent apoptosis in Candida dubliniensis biofilms.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2013 ;8(12):e86032. Epub 2013 Dec 23. PMID: 24376900
Article Published Date : Dec 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Candida Infection
Pharmacological Actions : Apoptotic
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation
[+]

Purpurin, a anthraquinone induces ROS-mediated A549 lung cancer cell apoptosis via inhibition of PI3K/AKT and proliferation.Jul 06, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharm Pharmacol. 2021 Jul 7 ;73(8):1101-1108. PMID: 33877317
Article Published Date : Jul 06, 2021
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Lung Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
[+]

Purpurin: A natural anthraquinone with multifaceted pharmacological activities.Apr 30, 2021

Pubmed Data : Phytother Res. 2021 May ;35(5):2418-2428. Epub 2020 Nov 30. PMID: 33254282
Article Published Date : Apr 30, 2021
Study Type : Review
Additional Links
Substances : Rubia Cordifolia
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

R. cordifolia attenuated diabetic neuropathy through its antidiabetic and analgesic properties by ameliorating apoptosis and oxidative stress.Nov 08, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2023 Nov 9 ;16(11). Epub 2023 Nov 9. PMID: 38004451
Article Published Date : Nov 08, 2023
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Diabetic Neuropathy
Pharmacological Actions : Anti-Apoptotic, Antioxidants
[+]

Rubia cordifolia L. ameliorates DSS-induced ulcerative colitis.Jul 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Heliyon. 2022 Aug ;8(8):e10314. Epub 2022 Aug 19. PMID: 36082330
Article Published Date : Jul 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation
[+]

Rubia cordifolia L. extract ameliorates vitiligo.Jun 25, 2025

Pubmed Data : J Ethnopharmacol. 2025 Jun 26 ;350:120027. Epub 2025 May 22. PMID: 40412781
Article Published Date : Jun 25, 2025
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Vitiligo
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-6 Downregulation
Additional Keywords : Plant Extracts
[+]

Structural and functional insights into the selective inhibition of mutant tau aggregation by purpurin and oleocanthal in frontotemporal dementia.Aug 31, 2025

Pubmed Data : Protein Sci. 2025 Sep ;34(9):e70240. PMID: 40862394
Article Published Date : Aug 31, 2025
Study Type : In Vitro Study
Additional Links
Substances : Oleocanthal, Rubia Cordifolia
Diseases : Dementia
Pharmacological Actions : Neuroprotective Agents
[+]

The natural anthraquinone dye purpurin exerts antibacterial activity by perturbing the FtsZ assembly.Nov 14, 2021

Pubmed Data : Bioorg Med Chem. 2021 Nov 15 ;50:116463. Epub 2021 Oct 11. PMID: 34700238
Article Published Date : Nov 14, 2021
Study Type : In Vitro Study
Additional Links
Substances : Rubia Cordifolia
Diseases : Bacillus subtilis infections
Pharmacological Actions : Anti-Bacterial Agents, Antineoplastic Agents

Copyright: nilanewsom / 123RF Stock Photo

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