Safflower

Name	AC	CK
Hypertension	7	29
Diabetic Nephropathy	4	24
Obesity	7	22
Oxidative Stress	13	22
Cerebral Ischemia	12	20
Myocardial Ischemia	13	19
Alzheimer's Disease	11	18
Stroke: Ischemic	5	17
Lipopolysaccharide-Induced Toxicity	11	16
Parkinson's Disease	8	15
Inflammation	8	12
Metabolic Syndrome X	2	12
Diabetes Mellitus: Type 2	6	11
Depression	5	10
Liver Cancer	7	9
Atherosclerosis	5	7
Breast Cancer	6	7
Osteoporosis	4	7
Brain Ischemia	4	6
Brain Injury: Traumatic	3	5
Cardiovascular Diseases	3	5
Colorectal Cancer	3	5
Dementia	3	5
Hyperglycemia	4	5
Myocardial Infarction	3	5
Chemically-Induced Liver Damage	2	4
Chemotherapy-Induced Toxicity: Cisplatin	2	4
Chronic Obstructive Pulmonary Disease	2	4
Cognitive Decline/Dysfunction	2	4
Hyperlipidemia	2	4
Hypoxia	2	4
Kidney Damage	2	4
Lipid Peroxidation	3	4
Liver Damage	2	4
Liver Fibrosis	2	4
Myocardial Fibrosis	2	4
Pulmonary Fibrosis: Bleomycin-Induced	2	4
Traumatic Brain Injury	2	4
Wound Healing	2	4
Asthma	2	3
Brain Inflammation	2	3
Brain: Oxidative Stress	2	3
Cerebrovascular Disorders	2	3
Diabetes: Oxidative Stress	2	3
Heat Stroke	2	3
Kidney Damage: Chemically-Induced	1	3
Neurodegenerative Diseases	3	3
Sepsis	2	3
Acetaminophen (Tylenol) Toxicity	1	2
Acute Respiratory Distress Syndrome	1	2
Alcohol Toxicity	1	2
Allergic Rhinitis	1	2
Androgenic Alopecia	1	2
Arthritis	1	2
C-Reactive Protein	1	2
Cancers: All	2	2
Chemotherapy-Induced Kidney Damage	1	2
Chemotherapy-Induced Toxicity: Bleomycin	1	2
Colitis	1	2
Coronary Artery Disease	1	2
Diabetes Mellitus: Type 1	1	2
Diabetic Retinopathy	1	2
Diabetic Ulcer	1	2
Edema	1	2
Endometritis	1	2
Hair Loss	1	2
High Fat Diet	1	2
High Fructose Diet	1	2
Homocysteine: Elevated	1	2
Hydrogen Peroxide Induced Toxicity	2	2
Infertility: Female	1	2
Infertility: Male	1	2
Intestinal Ischemia	1	2
Ischemia	1	2
Kidney Failure: Chronic	1	2
Lung Damage	1	2
Lung Injury: Acute	1	2
Memory Disorders	1	2
Muscle Damage	1	2
Osteoarthritis	2	2
Osteoarthritis: Knee	1	2
Osteonecrosis	1	2
Paraquat Toxicity	1	2
Polycystic Ovary Syndrome	1	2
Pulmonary Fibrosis	1	2
Squamous cell carcinoma	1	2
Staphylococcus aureus infection	1	2
Thrombosis	1	2
Tongue Cancer	1	2
Ulcerative Colitis	1	2
Aging	1	1
Alcoholic Liver Disease	1	1
Breast Cancer: Lung Metastasis	1	1
Breast Cancer: Triple Negative	1	1
Cancer Metastasis	1	1
Carcinoma: Non-Small-Cell Lung	1	1
Cardiomyopathy	1	1
Degenerative Disk Disease	1	1
Esophageal Cancer	1	1
Fibrosis	1	1
Gastric Cancer	1	1
Gram-Negative Bacterial Infections	1	1
Gram-Positive Bacterial Infections	1	1
Kidney Fibrosis	1	1
Lung Cancer	1	1
Nonalcoholic fatty liver disease (NAFLD)	1	1
Osteosarcoma	1	1
Skin Diseases	1	1

Name	AC	CK
Anti-Inflammatory Agents	57	119
Neuroprotective Agents	47	88
Antioxidants	39	80
Tumor Necrosis Factor (TNF) Alpha Inhibitor	20	51
Interleukin-6 Downregulation	15	46
Anti-Apoptotic	30	45
Interleukin-1 beta downregulation	19	39
Renoprotective	11	38
Cardioprotective	22	33
Vasoprotective	4	24
Antiproliferative	14	19
NF-kappaB Inhibitor	11	17
Antihypertensive Agents	3	13
Hepatoprotective	8	13
Nrf2 activation	7	13
Superoxide Dismutase Up-regulation	6	13
Insulin Sensitizers	2	12
Anti-Fibrotic	6	11
Apoptotic	8	10
Antidepressive Agents	4	8
Chemoprotective Agents	4	8
Heme oxygenase-1 up-regulation	5	8
Gastrointestinal Agents	4	7
Transforming growth factor beta (TGF-β) inhibitor	4	7
Malondialdehyde Down-regulation	3	6
Matrix metalloproteinase-9 (MMP-9) inhibitor	5	6
Osteoprotective	3	6
Angiogenesis Inducing Agents	3	5
Anti-metastatic	5	5
Hypoglycemic Agents	3	5
Autophagy Up-regulation	3	4
Bcl-2 protein down-regulation	3	4
Brain-derived neurotrophic factor modulator	2	4
Immunomodulatory	2	4
Nitric Oxide Inhibitor	2	4
Chemopreventive	2	3
Cyclooxygenase 2 Inhibitors	2	3
Interleukin-18 down-regulation	2	3
Pancreato Protective Agents	2	3
Alpha-glucosidase inhibitor	2	2
Analgesics	1	2
Anti-Asthmatic Agents	1	2
Anti-Bacterial Agents	1	2
Anticholesteremic Agents	1	2
Antimicrobial	2	2
Antinoceceptive	1	2
Antioxidant Effects	1	2
Catalase Up-Regulation	1	2
Cell cycle arrest	2	2
Detoxifier	1	2
Fertility Agents: Male	1	2
Hypolipidemic	1	2
Hypoxia-inducible factor-1 (HIF-1) inhibitor	1	2
Interleukin-2 Downregulation	1	2
Interleukin-4 downregulation	1	2
Interleukin-5 downregulation	1	2
Matrix metalloproteinase-2 (MMP-2) inhibitor	2	2
Neurogenesis	1	2
Vascular Endothelial Growth Factor Inhibitors	1	2
interleukin-13 down-regulation	1	2
Acetylcholinesterase Inhibitor	1	1
Angiogenesis Inhibitors	1	1
Anti-Angiogenic	1	1
Anti-atherogenic	1	1
Antineoplastic Agents	1	1
Autophagy Inhibitors	1	1
Chemotherapeutic	1	1
Cytotoxic	1	1
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	1	1
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	1	1
Postaglandin PGE2 downregulation	1	1

[+]

Antioxidant and anti-inflammatory properties of hydroxyl safflower yellow a in diabetic nephropathy.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2022 ;13:929169. Epub 2022 Aug 11. PMID: 36034830

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Drug Deliv. 2018 Nov ;25(1):1779-1789. PMID: 30338719

Article Published Date : Oct 31, 2018

Study Type : Animal Study

Additional Links

Substances : Safflower

Diseases : Wound Healing

Pharmacological Actions : Angiogenesis Inducing Agents

Additional Keywords : Natural Substance/Drug Synergy

[+]

Danshensu plus hydroxysafflor yellow A could achieve remarkable synergistic neuroprotective effects on ischemia-reperfusion injury.Dec 28, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2017 Dec 29 ;8(70):115434-115443. Epub 2017 Dec 15. PMID: 29383171

Article Published Date : Dec 28, 2017

Study Type : Animal Study

Additional Links

Substances : Safflower, Salvia miltiorrhiza

Diseases : Cerebral Ischemia

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, Nrf2 activation

Additional Keywords : Natural Substance Synergy

[+]

Effects of Carthamus tinctorius on semen quality and gonadal hormone levels in partially sterile male rats.Sep 30, 2012

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Metab Brain Dis. 2021 04 ;36(4):557-569. Epub 2021 Feb 6. PMID: 33550459

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Safflower

Diseases : Alzheimer's Disease

Pharmacological Actions : Anticholesteremic Agents, Hepatoprotective, Neuroprotective Agents

[+]

Hair growth-promoting effect of Carthamus tinctorius floret extract.Jun 30, 2014

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2014 Jul ;28(7):1030-6. Epub 2013 Dec 11. PMID: 24338940

Article Published Date : Jun 30, 2014

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Safflower

Diseases : Hair Loss

Pharmacological Actions : Transforming growth factor beta (TGF-β) inhibitor

Additional Keywords : Hair Regeneration, Plant Extracts

[+]

Herbal mixture of Carthamus tinctorius L. seed and Taraxacum coreanum attenuates amyloid beta-Induced cognitive dysfunction.Jan 05, 2022

Click here to read the entire abstract

Pubmed Data : Foods. 2022 Jan 6 ;11(2). Epub 2022 Jan 6. PMID: 35053874

Article Published Date : Jan 05, 2022

Study Type : Animal Study

Additional Links

Substances : Dandelion , Safflower

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Hydroethanolic extract of Carthamus tinctorius induces antidepressant-like effects.Aug 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2017 ;8:613. Epub 2017 Sep 6. PMID: 28932195

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Safflower

Diseases : Sepsis

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents

[+]

Hydroxysafflor yellow A attenuates the expression of inflammatory cytokines in acute soft tissue injury.Jan 10, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Cell Neurosci. 2018 ;12:371. Epub 2018 Oct 18. PMID: 30405354

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Safflower

Diseases : Cerebral Ischemia

Pharmacological Actions : Neuroprotective Agents

[+]

Hydroxysafflor yellow A inhibits endothelial cell ferroptosis in diabetic atherosclerosis.Nov 30, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Chem Biol Drug Des. 2022 Mar 23. Epub 2022 Mar 23. PMID: 35319164

Article Published Date : Mar 22, 2022

Study Type : Animal Study

Additional Links

Substances : Safflower

Diseases : Ulcerative Colitis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Hydroxysafflor yellow A regulates lymphangiogenesis and inflammation.Mar 31, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Protective effect of hydroxysafflor yellow A against acute kidney injury.Jan 14, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

[+]

Safflower flavonoid extract showed a significant anti-Parkinson's disease effect.Nov 08, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2021 Apr 22 ;275:114139. Epub 2021 Apr 22. PMID: 33894286

Article Published Date : Apr 21, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2020 ;11:482. Epub 2020 Apr 21. PMID: 32372961

Article Published Date : Dec 31, 2019

Study Type : Animal Study

Additional Links

Substances : Safflower

Diseases : Obesity

Pharmacological Actions : Antioxidants

Additional Keywords : Anti-Obesity Agents

[+]

Safflower yellow and its main component hydroxysafflor yellow A alleviate hyperleptinemia in diet-induced obesity.Mar 20, 2023

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2023 Mar 21. Epub 2023 Mar 21. PMID: 36943416

Article Published Date : Mar 20, 2023

Study Type : Animal Study

Additional Links

Substances : Safflower

Diseases : Obesity

Additional Keywords : Anti-Obesity Agents

[+]

Safflower yellow improves insulin sensitivity in high-fat diet-induced obesity.Oct 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Diabetes Investig. 2020 Nov ;11(6):1457-1469. Epub 2020 Jun 5. PMID: 32356607

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2016 Aug 24 ;21(9). Epub 2016 Aug 24. PMID: 27563865

Article Published Date : Aug 23, 2016

Study Type : Animal Study

Additional Links

Substances : Safflower

Diseases : Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Plant Extracts

[+]

The cardioprotective effects and mechanisms of astragalus-safflower herb pairs on coronary heart disease.May 21, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Biosci (Landmark Ed). 2023 May 22 ;28(5):94. PMID: 37258471

Click here to read the entire abstract

Pubmed Data : Environ Toxicol. 2019 Dec ;34(12):1320-1328. Epub 2019 Sep 4. PMID: 31486215

Article Published Date : Nov 30, 2019

Study Type : In Vitro Study

Additional Links

Substances : Safflower

Diseases : Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Apoptotic, Bcl-2 protein down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

C. tinctorius flower can act as a biological antioxidant in a cell culture experimental model and protect osteoblasts from oxidative stress-induced toxicity.Jun 30, 2010

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2010 Jul ;24(7):1037-41. PMID: 19960423

Article Published Date : Jun 30, 2010

Study Type : In Vitro Study

Additional Links

Substances : Safflower

Diseases : Hydrogen Peroxide Induced Toxicity, Lipid Peroxidation, Oxidative Stress

Pharmacological Actions : Antioxidants

[+]

Carthamus tinctorius L could potentially serve as a cardio-protective agent against LPS-induced apoptosis.Aug 08, 2010

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncol Res. 2024 ;32(5):899-910. Epub 2024 Apr 23. PMID: 38686047

Article Published Date : Dec 31, 2023

Study Type : In Vitro Study

Additional Links

Substances : Safflower

Diseases : Osteosarcoma

Pharmacological Actions : Antiproliferative , Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

[+]

Hydroxysafflor yellow A induces autophagy in human liver cancer cells.Mar 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Thorac Cancer. 2019 06 ;10(6):1319-1333. Epub 2019 May 4. PMID: 31055884

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2020 ;11:579332. Epub 2020 Dec 11. PMID: 33536906

Article Published Date : Dec 31, 2019

Study Type : Review

Additional Links

Substances : Safflower

Diseases : Cancers: All, Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

Hydroxysafflor-yellow A induces human gastric carcinoma BGC-823 cell apoptosis.Feb 07, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Chin Herb Med. 2023 Jan ;15(1):86-93. Epub 2022 Dec 16. PMID: 36875432

Article Published Date : Dec 31, 2022

Study Type : In Vitro Study

Additional Links

Substances : Safflower

Diseases : Aging

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants

[+]

Protective effects of hydroxysafflor yellow A on alcohol-induced liver injury. Feb 28, 2015

Click here to read the entire abstract

Pubmed Data : J Physiol Biochem. 2015 Mar ;71(1):69-78. Epub 2015 Jan 28. PMID: 25626885

Article Published Date : Feb 28, 2015

Study Type : In Vitro Study

Additional Links

Substances : Safflower

Diseases : Alcoholic Liver Disease, Lipid Peroxidation

Pharmacological Actions : Hepatoprotective, Transforming growth factor beta (TGF-β) inhibitor

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Med Rep. 2015 Jun ;11(6):4611-6. Epub 2015 Feb 6. PMID: 25673029

Article Published Date : May 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Safflower

Diseases : Breast Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Bcl-2 protein down-regulation, Matrix metalloproteinase-9 (MMP-9) inhibitor

Additional Keywords : Polysaccharides

[+]

Click here to read the entire abstract

Pubmed Data : Curr Drug Deliv. 2022 Apr 13. Epub 2022 Apr 13. PMID: 35422215

Article Published Date : Apr 12, 2022

Study Type : In Vitro Study

Additional Links

Substances : Safflower

Diseases : Cardiomyopathy, Sepsis

Pharmacological Actions : Cardioprotective

[+]

α-Glucosidase, butyrylcholinesterase and acetylcholinesterase inhibitory activities of phenolic compounds from Carthamus tinctorius L. flowers.Jun 30, 2024

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Saudi Pharm J. 2024 Jul ;32(7):102106. Epub 2024 May 16. PMID: 38831925

Article Published Date : Jun 30, 2024

Study Type : In Vitro Study

Additional Links

Substances : Safflower

Diseases : Alzheimer's Disease, Hyperglycemia

Pharmacological Actions : Acetylcholinesterase Inhibitor, Alpha-glucosidase inhibitor , Neuroprotective Agents

[+]

Safflower contains compounds with neuroprotective properties.Dec 12, 2008

Click here to read the entire abstract

Pubmed Data : Neurochem Res. 2008 Dec 12. [Epub ahead of print] PMID: 19082884

Article Published Date : Dec 12, 2008

Additional Links

Substances : Safflower

Safflower jQuery(function ($) { $(".node-field-image").click(function () { $(".node-field-image").toggleClass("open"); }); $(".node.topic>.colfull").click(function () { $(".node.topic>.colfull").toggleClass("open"); }); })

Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 187 Abstracts with Safflower Research

Limited to Members Only

Currently Available Sorting Options

Antioxidant and anti-inflammatory properties of hydroxyl safflower yellow a in diabetic nephropathy.Dec 31, 2021

Conjugated linoleic acid and safflower oil improve body composition in obese postmenopausal women with type 2 diabetes mellitus.Sep 01, 2009

Effect and safety of hydroxysafflor yellow A for injection in patients with acute ischemic stroke of blood stasis syndrome.May 31, 2020

Effects of safflower seed extract on arterial stiffness.Nov 02, 2010

Effects of safflower seed extract on arterial stiffness.Nov 02, 2010

Safflower oil could improve abdominal obesity, blood pressure, and insulin resistance in patients with metabolic syndrome.Jan 09, 2022

The impact of virgin coconut oil and high-oleic safflower oil on body composition, lipids, and inflammatory markers in postmenopausal women.Mar 08, 2017

Protective effect of hydroxysafflor yellow A on cyclosporin A-induced renal oxidative stress.Dec 31, 2021

Hydroxysafflor yellow A increases BDNF and NMDARs in the hippocampus in a vascular dementia.Dec 31, 2015

Antioxidant effects of hydroxysafflor yellow A and acetyl-11-keto-β-boswellic acid in combination on isoproterenol-induced myocardial injury.May 31, 2016

Antitumor proliferation and related mechanism of ultrasound irradiation combined with safflower yellow.Dec 31, 2021

Carthamin yellow protects the heart against ischemia/reperfusion injury.Dec 31, 2018

Carthamus red may serve as a candidate with strong a hepatoprotective effect and antioxidant activity in liver damage.Jul 08, 2013

Carthamus tinctorius extract ameliorated hemodynamic alteration and vascular remodelling in 2K-1C hypertensive rats.Feb 28, 2018

Carthamus tinctorius has significant hypoglycemic effects compared to diabetic control group treated with glibenclamide.Feb 28, 2014

Carthamus tinctorius L. ameliorates brain injury followed by cerebral ischemia-reperfusion.Nov 30, 2016

Carthamus tinctorius L. Extract ameliorates cerebral ischemia-reperfusion injury.Feb 29, 2020

Carthamus Tinctorius L. extract attenuates cardiac remodeling in L-NAME-induced hypertensive rats.Feb 28, 2019

Carthamus tinctorius L. extract possess remarkable antinociceptive and anti-inflammatory activities.Feb 02, 2014

Carthamus tinctorius L. seed may play role in the prevention of alcohol-related dementia.Sep 30, 2018

Carthamus tinctorius may be used as an alternative therapeutic agent while treating patients with anxiety and depressive disorders.Apr 30, 2015

Cathamus tinctorius represents a potential treatment option for obesity and associated metabolic disorders, including hyperlipidemia.Dec 31, 2015

Co-delivery of deferoxamine and hydroxysafflor yellow A to accelerate diabetic wound healing via enhanced angiogenesis.Oct 31, 2018

Danshensu plus hydroxysafflor yellow A could achieve remarkable synergistic neuroprotective effects on ischemia-reperfusion injury.Dec 28, 2017

Effects of Carthamus tinctorius on semen quality and gonadal hormone levels in partially sterile male rats.Sep 30, 2012

Effects of hydroxysafflor yellow A on rats with collagen-induced arthritis.Sep 16, 2021

Effects of hydroxysafflor yellow A on the PI3K/AKT pathway and apoptosis of pancreatic β-Cells in type 2 diabetes mellitus.Dec 31, 2019

Effects of safflower yellow on cholesterol levels in serum and brain tissue of APP/PS1 mice.Dec 31, 2020

Hair growth-promoting effect of Carthamus tinctorius floret extract.Jun 30, 2014

Herbal mixture of Carthamus tinctorius L. seed and Taraxacum coreanum attenuates amyloid beta-Induced cognitive dysfunction.Jan 05, 2022

Hydroethanolic extract of Carthamus tinctorius induces antidepressant-like effects.Aug 31, 2017

Hydroxy-safflower yellow A alleviates osteoporosis.Dec 31, 2020

Hydroxy-safflower yellow A mitigates vascular remodeling in rat pulmonary arterial hypertension.Dec 31, 2023

Hydroxyl safflower yellow A regulates the tumor immune microenvironment to produce an anticancer effect in a model of hepatocellular carcinoma.Feb 28, 2019

Hydroxysafflor yellow A actives BK Ca channels and inhibits L-type Ca channels to induce vascular relaxation.Mar 04, 2020

Hydroxysafflor yellow A alleviates acute myocardial ischemia/reperfusion injury.Jul 30, 2023

Hydroxysafflor yellow A alleviates cerebral ischemia reperfusion injury.Apr 30, 2021

Hydroxysafflor yellow A alleviates lipopolysaccharide-induced acute respiratory distress syndrome.Dec 31, 2016

Hydroxysafflor yellow A alleviates myocardial ischemia/reperfusion in hyperlipidemia.Jan 11, 2016

Hydroxysafflor yellow A alleviates ovalbumin-induced asthma.Dec 31, 2018

Hydroxysafflor yellow A ameliorates depression-like behavior in Parkinson's disease.Feb 29, 2024

Hydroxysafflor yellow A ameliorates homocysteine-induced Alzheimer-like pathologic dysfunction and memory/synaptic disorder.Nov 30, 2013

Hydroxysafflor yellow A ameliorates lipopolysaccharide-induced acute lung injury.Nov 30, 2014

Hydroxysafflor yellow A attenuates allergic response of ovalbumin induced allergic rhinitis.Jun 30, 2023

Hydroxysafflor yellow A attenuates bleomycin-induced pulmonary fibrosis.Mar 31, 2016

Hydroxysafflor yellow A attenuates heat stroke-induced acute lung injury.Dec 19, 2022

Hydroxysafflor yellow a attenuates small airway remodeling in a rat model of chronic obstructive pulmonary disease.Dec 31, 2013

Hydroxysafflor yellow A attenuates the apoptosis of peripheral blood CD4 + T lymphocytes in a murine model of sepsis.Dec 31, 2016

Hydroxysafflor yellow A attenuates the expression of inflammatory cytokines in acute soft tissue injury.Jan 10, 2017

Hydroxysafflor yellow A can improve depressive behavior by inhibiting hippocampal inflammation and oxidative stress through regulating HPA axis.Dec 31, 2021

Hydroxysafflor yellow a confers neuroprotection against acute traumatic brain injury.May 22, 2023

Hydroxysafflor yellow A confers neuroprotection from focal cerebral ischemia.Oct 31, 2020

Hydroxysafflor yellow A could alleviate inflammatory cell infiltration and other pathological changes in the lungs of chronic obstructive pulmonary disease.Sep 30, 2019

Hydroxysafflor yellow A exerts beneficial effects by restoring hormone secretion and alleviating oxidative stress in polycystic ovary syndrome.Dec 31, 2019

Hydroxysafflor yellow A exerts neuroprotective effects by inhibiting protein carbonyl formation in cerebral ischemia-reperfusion injury.Feb 29, 2024

Hydroxysafflor yellow A exerts neuroprotective effects in cerebral ischemia reperfusion.Dec 14, 2015

Hydroxysafflor yellow A improved motor dysfunction in rotenone-induced Parkinson's disease model.Apr 30, 2017

Hydroxysafflor yellow A improved retinopathy via Nrf2/HO-1 pathway.Dec 31, 2021

Hydroxysafflor yellow A improves learning and memory in cerebral ischemia reperfusion-injured.Dec 31, 2017

Hydroxysafflor yellow A inhibits endothelial cell ferroptosis in diabetic atherosclerosis.Nov 30, 2023

Hydroxysafflor yellow A inhibits staphylococcus aureus-induced mouse endometrial inflammation.Mar 17, 2021

Hydroxysafflor yellow A inhibits the hyperactivation of rat platelets by regulating the miR-9a-5p/SRC axis.Sep 30, 2023

Hydroxysafflor Yellow A inhibits the viability and migration of vascular smooth muscle cells induced by serum from rats with chronic renal failure.Jul 31, 2021

Hydroxysafflor Yellow A may have utility as a post-IS neuroprotective agent.Mar 15, 2022

Hydroxysafflor Yellow A mitigated myocardial ischemia/reperfusion injury.Jul 31, 2019

Hydroxysafflor yellow A mitigates myocardial fibrosis induced by isoproterenol and angiotensin II.Dec 31, 2021

Hydroxysafflor yellow A promotes α-synuclein clearance via regulating autophagy in rotenone-induced Parkinson's disease.Dec 31, 2017

Hydroxysafflor yellow A protects against cerebral ischemia-reperfusion injury.Oct 31, 2013

Hydroxysafflor yellow A protects against colitis.May 14, 2023

Hydroxysafflor yellow A protects against ulcerative colitis.Mar 22, 2022

Hydroxysafflor yellow A regulates lymphangiogenesis and inflammation.Mar 31, 2023

Hydroxysafflor yellow A suppresses liver fibrosis induced by carbon tetrachloride with high-fat diet.Aug 31, 2014

Safflower

View the Evidence:
187 Abstracts with Safflower Research