Safranal

Views 157
Jump to
Abstracts Focused Research Topics
Your Token Count0

Sign in to Purchase/Download Documents

Sign in / Register

Focus Your Research

Click any topic below to filter + focus research
20 Diseases Researched for Safranal
NameACCKFocus
Allodynia12Locked
Asthma12Locked
Brain: Oxidative Stress12Locked
Cerebral Ischemia12Locked
Depression12Locked
Diabetic Nephropathy12Locked
Excitotoxicity 12Locked
Hypertension12Locked
Neuropathic Pain12Locked
Parkinson's Disease12Locked
Stroke: Attenuation/Recovery 12Locked
Cancers: All11Locked
Cervical Cancer11Locked
Escherichia coli Infections11Locked
Helicobacter Pylori Infection11Locked
Immune Dysregulation: TH1/TH2 imbalance11Locked
Leishmaniasis11Locked
Oral Cancer11Locked
Plasmodium Infections11Locked
Squamous cell carcinoma11Locked
19 Pharmacological Actions Researched for Safranal
NameACCKFocus
Antioxidants36Locked
Neuroprotective Agents36Locked
Anti-Apoptotic12Locked
Anti-Asthmatic Agents12Locked
Anti-Bacterial Agents22Locked
Anti-Inflammatory Agents12Locked
Antidepressive Agents12Locked
Excitatory Amino Acid Agonists12Locked
Hypoglycemic Agents12Locked
Nitric Oxide Inhibitor12Locked
Nrf2 activation12Locked
Vasodilator Agents12Locked
Antiparasitic Agents11Locked
Antiproliferative 11Locked
Apoptotic11Locked
Chemopreventive11Locked
Immunomodulatory11Locked
Interferon-gamma (IFN-gamma) inducer11Locked
Interleukin-4 upregulation11Locked

View the Evidence:
27 Abstracts with Safranal Research

[+]

It is recommended that safranal be considered for diabetes management.Aug 05, 2018

Pubmed Data : Biomed Pharmacother. 2018 Aug 6 ;107:203-211. Epub 2018 Aug 6. PMID: 30092399
Article Published Date : Aug 05, 2018
Study Type : Animal Study
Additional Links
Substances : Safranal
Diseases : Diabetes: Cognitive Dysfunction, Diabetes Mellitus: Type 1
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants
[+]

N-Acetylcysteine and Safranal prevented the brain damage induced by hyperthyroidism.Apr 06, 2020

Pubmed Data : Nutr Neurosci. 2020 Apr 7:1-15. Epub 2020 Apr 7. PMID: 32264788
Article Published Date : Apr 06, 2020
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine), Safranal
Diseases : Hyperthyroidism
Pharmacological Actions : Neuroprotective Agents
[+]

Safranal ameliorates myocardial ischemia.Jun 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacol Sci. 2020 Jul ;143(3):156-164. Epub 2020 Mar 23. PMID: 32278466
Article Published Date : Jun 30, 2020
Study Type : Animal Study
Additional Links
Substances : Safranal
Diseases : Myocardial Ischemia
Pharmacological Actions : Antioxidants, Cardioprotective
[+]

Safranal attenuates cognitive deficits in amyloid β-induced rat model of Alzheimer's disease.Aug 16, 2019

Pubmed Data : Metab Brain Dis. 2019 Aug 17. Epub 2019 Aug 17. PMID: 31422512
Article Published Date : Aug 16, 2019
Study Type : Animal Study
Additional Links
Substances : Safranal
Diseases : Alzheimer's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Safranal carried by nanostructured lipid vehicles inhibits generalized epilepsy in mice.Jan 01, 2018

Pubmed Data : Pharmazie. 2018 04 2 ;73(4):207-212. PMID: 29609687
Article Published Date : Jan 01, 2018
Study Type : Animal Study
Additional Links
Substances : Safranal
Diseases : Epilepsy
Pharmacological Actions : Anticonvulsants
[+]

Safranal has an anti-inflammatory potential and has a strong antioxidative effect.May 22, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : An Acad Bras Cienc. 2019 May 23 ;91(2):e20181235. Epub 2019 May 23. PMID: 31141017
Article Published Date : May 22, 2019
Study Type : Animal Study
Additional Links
Substances : Safranal
Diseases : Chemically-Induced Liver Damage, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective
[+]

Safranal is thought to be used as an effective combination in controlling metabolic complications caused by olanzapine.Nov 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2019 Dec ;22(12):1476-1482. PMID: 32133067
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : Safranal
Diseases : Schizophrenia
Pharmacological Actions : Anticholesteremic Agents, Antihypertensive Agents
Problem Substances : Olanzapine
[+]

Safranal may serve as a potent and promising therapeutic drug for the treatment of Parkinson's disease.Dec 29, 2016

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2016 Dec 30 ;62(14):11-17. Epub 2016 Dec 30. PMID: 28145852
Article Published Date : Dec 29, 2016
Study Type : Animal Study
Additional Links
Substances : Safranal
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

Safranal might be effective against depressant-like effects induced by chronic stress via modulating brain oxidative response.Aug 29, 2017

Pubmed Data : Neurosci Lett. 2017 Aug 30. Epub 2017 Aug 30. PMID: 28866053
Article Published Date : Aug 29, 2017
Study Type : Animal Study
Additional Links
Substances : Safranal
Diseases : Brain: Oxidative Stress, Depression
Pharmacological Actions : Antidepressive Agents, Antioxidants
[+]

Safranal pretreatment to these allergically inflamed mice lead to a significant decrease in airway hyper-responsiveness and airway cellular infiltration to the lungs.Mar 31, 2015

Pubmed Data : Phytother Res. 2015 Apr ;29(4):617-27. Epub 2015 Mar 10. PMID: 25756352
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Safranal
Diseases : Asthma
Pharmacological Actions : Anti-Apoptotic, Anti-Asthmatic Agents, Nitric Oxide Inhibitor
[+]

Safranal, a constituent of Saffron, reduces kainic Acid treatment-induced glutamate and aspartate concentrations in the rat hippocampus. Oct 01, 2008

Pubmed Data : Planta Med. 2008 Oct;74(12):1441-5. Epub 2008 Sep 24. PMID: 18816431
Article Published Date : Oct 01, 2008
Study Type : Animal Study
Additional Links
Substances : Saffron, Safranal
Diseases : Excitotoxicity
Pharmacological Actions : Excitatory Amino Acid Agonists
[+]

The relaxant activity of safranal is mediated predominantly through an endothelium independent mechanism.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacopuncture. 2016 Dec ;19(4):329-335. PMID: 28097042
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Safranal
Diseases : Hypertension
Pharmacological Actions : Vasodilator Agents
[+]

The results of the present study showed neuroprotective effects of crocin, safranal and insulin in a rat model of diabetic neuropathy.Aug 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2015 Sep-Oct;5(5):469-78. PMID: 26468467
Article Published Date : Aug 31, 2015
Study Type : Animal Study
Additional Links
Substances : Crocin, Safranal
Diseases : Diabetic Nephropathy
Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Neuroprotective Agents
[+]

This study concluded that safranal had protective effects on ischemic reperfusion injury in the rat model of stroke.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Folia Neuropathol. 2017 ;55(3):206-213. PMID: 28984113
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Safranal
Diseases : Cerebral Ischemia, Stroke: Attenuation/Recovery
Pharmacological Actions : Neuroprotective Agents
[+]

This study confirmed the antiallodynia effect of safranal, main volatile fraction of saffron, in a neuropathic pain model induced by spinal nerve transaction.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Clin Exp Med. 2014 ;7(12):4990-6. Epub 2014 Dec 15. PMID: 25663997
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Safranal
Diseases : Allodynia, Neuropathic Pain
Pharmacological Actions : Anti-Inflammatory Agents
[+]

TRPA1 mediates the antinociceptive properties of safranal.Jan 11, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2019 Jan 12. Epub 2019 Jan 12. PMID: 30636360
Article Published Date : Jan 11, 2019
Study Type : Animal Study
Additional Links
Substances : Safranal
Diseases : Chronic Pain
Pharmacological Actions : Antinoceceptive
[+]

Crocin and safranal exerted apoptotic effects in KB cell line.Jul 17, 2017

Pubmed Data : Nutr Cancer. 2017 Jul 18:1-9. Epub 2017 Jul 18. PMID: 28718677
Article Published Date : Jul 17, 2017
Study Type : In Vitro Study
Additional Links
Substances : Crocin, Safranal
Diseases : Oral Cancer, Squamous cell carcinoma
Pharmacological Actions : Apoptotic
[+]

Protective effects of saffron and its active components against oxidative stress and apoptosis in endothelial cells.Dec 31, 2017

Pubmed Data : Microvasc Res. 2018 07 ;118:82-89. Epub 2018 Mar 7. PMID: 29524452
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carotenoids, Crocin, Saffron, Safranal
Diseases : Endothelial Damage, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants
Additional Keywords : Plant Extracts
[+]

Safranal alleviates dextran sulfate sodium-induced colitis and suppresses macrophage-mediated inflammation.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:1281. Epub 2019 Nov 1. PMID: 31736758
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Safranal
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Safranal and its analogs inhibit Escherichia coli ATP synthase and cell growth.Jan 31, 2017

Pubmed Data : Int J Biol Macromol. 2017 Feb ;95:145-152. Epub 2016 Nov 16. PMID: 27865956
Article Published Date : Jan 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Safranal
Diseases : Escherichia coli Infections
Pharmacological Actions : Anti-Bacterial Agents
[+]

Safranal exhibits oligoprotection potential by means of inhibiting oxidative stress parameters.Nov 20, 2018

Pubmed Data : Drug Res (Stuttg). 2018 Nov 21. Epub 2018 Nov 21. PMID: 30463091
Article Published Date : Nov 20, 2018
Study Type : In Vitro Study
Additional Links
Substances : Safranal
Diseases : Multiple Sclerosis, Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Safranal induces DNA double-strand breakage and ER-stress-mediated cell death in hepatocellular carcinoma cells.Nov 15, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2018 Nov 16 ;8(1):16951. Epub 2018 Nov 16. PMID: 30446676
Article Published Date : Nov 15, 2018
Study Type : In Vitro Study
Additional Links
Substances : Safranal
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, Cell cycle arrest
[+]

Safranal inhibits HeLa cell viability by perturbing the reassembly potential of microtubules.Oct 10, 2017

Pubmed Data : Phytother Res. 2017 Oct 11. Epub 2017 Oct 11. PMID: 29024138
Article Published Date : Oct 10, 2017
Study Type : In Vitro Study
Additional Links
Substances : Safranal
Diseases : Cervical Cancer
Pharmacological Actions : Antiproliferative
[+]

Safranal may have therapeutic effects in inflammatory diseases associated with Th1/Th2 imbalance.Nov 30, 2016

Pubmed Data : Iran J Immunol. 2016 Dec ;13(4):263-273. PMID: 27999238
Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Safranal
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory, Interferon-gamma (IFN-gamma) inducer, Interleukin-4 upregulation
[+]

Safranal showed anti-apoptotic and antioxidant effects and may exert promising potential for the prevention of Alzheimer's disease.Nov 05, 2018

Pubmed Data : Metab Brain Dis. 2018 Nov 6. Epub 2018 Nov 6. PMID: 30402809
Article Published Date : Nov 05, 2018
Study Type : In Vitro Study
Additional Links
Substances : Safranal
Diseases : Alzheimer's Disease
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
[+]

The components of crocus sativus have potential anti-bacterial and anti-parasitic effects.Mar 12, 2015

Pubmed Data : J Enzyme Inhib Med Chem. 2015 Mar 13:1-7. Epub 2015 Mar 13. PMID: 25766747
Article Published Date : Mar 12, 2015
Study Type : In Vitro Study
Additional Links
Substances : Crocin, Saffron, Safranal
Diseases : Helicobacter Pylori Infection, Leishmaniasis, Plasmodium Infections
Pharmacological Actions : Anti-Bacterial Agents, Antiparasitic Agents
[+]

This review provides a brief insight into the anticancer properties of saffron and its components. Mar 31, 2015

Pubmed Data : J Tradit Complement Med. 2015 Apr ;5(2):81-7. Epub 2015 Jan 28. PMID: 26151016
Article Published Date : Mar 31, 2015
Study Type : Review
Additional Links
Substances : Crocetin, Crocin, Saffron, Safranal
Diseases : Cancers: All
Pharmacological Actions : Chemopreventive

Copyright: viperagp / 123RF Stock Photo

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.

Connect with GreenMedInfo

MeWe

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2020 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.