Saw Palmetto

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26 Diseases Researched for Saw Palmetto
NameACCKFocus
Prostatic Hyperplasia: Benign1590Locked
Prostatitis: Chronic220Locked
Prostate Cancer615Locked
Lower Urinary Tract Symptoms212Locked
Alopecia: Androgenic110Locked
Bladder Outlet Obstruction110Locked
Chronic Pelvic Pain Syndrome110Locked
Erectile Dysfunction110Locked
Low Testosterone110Locked
Male Hormone Imbalances110Locked
Male Pattern Baldness110Locked
Prostatitis: Bacterial110Locked
Testosterone: Too Low110Locked
Urinary Flow Problems110Locked
Urinary Retention110Locked
Hair Loss23Locked
Inflammation12Locked
Lipopolysaccharide-Induced Toxicity12Locked
Prostatic Hyperplasia12Locked
Alopecia11Locked
Androgenic Alopecia11Locked
Breast Cancer11Locked
Cancers: All11Locked
Infertility: Male11Locked
Multiple Myeloma11Locked
Overactive Bladder11Locked
18 Pharmacological Actions Researched for Saw Palmetto
NameACCKFocus
5-alpha reductase inhibitor624Locked
Anti-Inflammatory Agents618Locked
Adrenergic alpha-Antagonists211Locked
Analgesics110Locked
Anti-Androgen110Locked
Anti-Bacterial Agents110Locked
Aromatase Inhibitors110Locked
Antioxidants23Locked
Anti-Apoptotic12Locked
Antiproliferative 12Locked
Regenerative12Locked
Adrenergic alpha-Agonists11Locked
Calcium Channel Blockers11Locked
Cholinergic Antagonists11Locked
Cyclooxygenase 2 Inhibitors11Locked
Fertility Agents: Male11Locked
Interleukin-6 Downregulation11Locked
Interleukin-8 downregulation11Locked
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View the Evidence:
42 Abstracts with Saw Palmetto Research

[+]

A systematic review of the literature showed that Permixon was effective for relieving urinary symptoms due to prostate enlargement.Nov 30, 2016

Pubmed Data : Eur Urol Focus. 2016 Dec ;2(5):553-561. Epub 2016 Apr 23. PMID: 28723522
Article Published Date : Nov 30, 2016
Study Type : Meta Analysis, Review
Additional Links
Substances : Saw Palmetto
Diseases : Prostatic Hyperplasia: Benign
Additional Keywords : Natural Substances Versus Drugs, Plant Extracts
[+]

A combination of Saw Palmetto, Nettle, Curcumin and Quercetin significantly improves treatment outcome of prulifloxacin in bacterial prostatitis patients. Jun 01, 2009

Pubmed Data : Int J Antimicrob Agents. 2009 Jun;33(6):549-53. Epub 2009 Jan 31. PMID: 19181486
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Substances : Curcumin, Nettle, Quercetin, Saw Palmetto
Diseases : Prostatitis: Chronic
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

A comparative study on the efficacy of phytosterol-enriched and conventional saw palmetto oil in mitigating benign prostate hyperplasia and androgen deficiency.Jul 02, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Urol. 2020 Jul 3 ;20(1):86. Epub 2020 Jul 3. PMID: 32620155
Article Published Date : Jul 02, 2020
Study Type : Human Study
Additional Links
Substances : Beta Sitosterol, Saw Palmetto
Diseases : Prostatic Hyperplasia: Benign
Additional Keywords : Phytotherapy, Plant Extracts
[+]

A dietary supplement containing astaxanthin and saw palmetto berry extract decrease dihydrotestosterone, increase testosterone and decrease estradiol levels in healthy males. Sep 01, 2009

Pubmed Data : J Cardiovasc Electrophysiol. 2009 Sep;20(9):1055-60. Epub 2009 Apr 30. PMID: 18700016
Article Published Date : Sep 01, 2009
Study Type : Human Study
Additional Links
Substances : Astaxanthin, Saw Palmetto
Diseases : Low Testosterone, Male Hormone Imbalances, Testosterone: Too Low
Pharmacological Actions : Aromatase Inhibitors
Additional Keywords : DHT Blocker
[+]

An extract of saw palmetto compares favorably with the drug tamsulosin in the treatment of benign prostatic hyperplasia. Jun 01, 2002

Pubmed Data : Prog Urol. 2002 Jun;12(3):384-92; discussion 394-4. PMID: 12189744
Article Published Date : Jun 01, 2002
Study Type : Human Study
Additional Links
Substances : Saw Palmetto
Diseases : Prostatic Hyperplasia: Benign
Pharmacological Actions : Adrenergic alpha-Antagonists, Anti-Androgen
Additional Keywords : Drug: Tamsulosin, Natural Substances Versus Drugs, Plant Extracts
[+]

Beneficial effects of Saw palmetto fruit extract on urinary symptoms in Japanese female subjects.Mar 10, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Mar 11 ;14(6). Epub 2022 Mar 11. PMID: 35334848
Article Published Date : Mar 10, 2022
Study Type : Human Study
Additional Links
Substances : Saw Palmetto
Diseases : Lower Urinary Tract Symptoms, Prostatic Hyperplasia
Additional Keywords : Plant Extracts
[+]

Flower pollen extract in association with vitamins versus Serenoa repens in chronic prostatitis/chronic Pelvic pain syndrome.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antiinflamm Antiallergy Agents Med Chem. 2019 ;18(2):151-161. PMID: 30488800
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Folic Acid , Pollen: Flower, Riboflavin (Vitamin B-2), Saw Palmetto, Thiamine (B-1) , Vitamin B-12, Vitamin B-6
Diseases : Chronic Pelvic Pain Syndrome, Prostatitis: Chronic
Pharmacological Actions : Analgesics
Additional Keywords : Plant Extracts
[+]

Pine Bark Extract, Saffron, Saw Palmetto for three months significantly improved sexual function, urinary symptoms.Aug 31, 2016

Pubmed Data : Minerva Urol Nefrol. 2016 Sep 1. Epub 2016 Aug 1. PMID: 27583656
Article Published Date : Aug 31, 2016
Study Type : Human Study
Additional Links
Substances : Pine Bark Extract, Saffron, Saw Palmetto
Diseases : Erectile Dysfunction, Lower Urinary Tract Symptoms
Additional Keywords : Plant Extracts, Significant Treatment Outcome
[+]

Pumpkin seed oil and saw palmetto oil may be effective as complementary and alternative medicine treatments for benign prostatic hyperplasia.Dec 31, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res Pract. 2009 ;3(4):323-7. Epub 2009 Dec 31. PMID: 20098586
Article Published Date : Dec 31, 2008
Study Type : Human Study
Additional Links
Substances : Pumpkin, Saw Palmetto
Diseases : Prostatic Hyperplasia: Benign
[+]

Saw palmetto (Serona repens) significantly reduces the clinical progression rates in men with mild symptoms of Bladder Outlet Obstruction. Nov 15, 1996

Pubmed Data : Circulation. 1996 Nov 15;94(10):2369-72. PMID: 16175413
Article Published Date : Nov 15, 1996
Study Type : Human Study
Additional Links
Substances : Saw Palmetto
Diseases : Bladder Outlet Obstruction, Urinary Flow Problems, Urinary Retention
[+]

Saw palmetto compares favorably with the drug Flomax (tamsulosin) to alleviate benign prostatic hyperplasia (BPH). Jan 01, 2007

Pubmed Data : Int Urol Nephrol. 2007;39(3):879-86. Epub 2007 Jan 4. PMID: 17203353
Article Published Date : Jan 01, 2007
Study Type : Human Study
Additional Links
Substances : Saw Palmetto
Diseases : Prostatic Hyperplasia: Benign
Additional Keywords : Drug: Tamsulosin, Natural Substances Versus Drugs, Plant Extracts
[+]

Saw palmetto inhibits 5-alpha reducatase activity in prostate cancer cell lines without interfering with PSA expression as is the case for pharmaceutical 5-alpha reductase inhibitors. Dec 01, 2006

Pubmed Data : Clin Nutr. 2006 Dec;25(6):923-38. Epub 2006 May 11. PMID: 15543614
Article Published Date : Dec 01, 2006
Study Type : Human Study
Additional Links
Substances : Saw Palmetto
Diseases : Prostate Cancer
Pharmacological Actions : 5-alpha reductase inhibitor
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Serenoa repens extract was effective, safe, and well-tolerated for lower urinary tract symptoms/benign prostatic hyperplasia.Mar 13, 2019

Pubmed Data : Urology. 2019 Mar 14. Epub 2019 Mar 14. PMID: 30880074
Article Published Date : Mar 13, 2019
Study Type : Human Study
Additional Links
Substances : Saw Palmetto
Diseases : Prostatic Hyperplasia: Benign
[+]

Serenoa repens seems to reduce prostatic inflammation in terms of histological and immunohistochemical parameters.Jul 18, 2018

Pubmed Data : World J Urol. 2018 Jul 19. Epub 2018 Jul 19. PMID: 30027406
Article Published Date : Jul 18, 2018
Study Type : Human Study
Additional Links
Substances : Saw Palmetto
Diseases : Prostatic Hyperplasia: Benign
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

The combination of serenoa repens, selenium, lycopene and bromelain are beneficial in patients with chronic bacterial prostatitis.Oct 04, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Ital Urol Androl. 2016 Oct 5 ;88(3):177-182. Epub 2016 Oct 5. PMID: 27711089
Article Published Date : Oct 04, 2016
Study Type : Human Study
Additional Links
Substances : Bromelain, Lycopene, Saw Palmetto, Selenium
Diseases : Prostatitis: Bacterial
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Natural Substance/Drug Synergy, Plant Extracts
[+]

The efficacy and safety of Serenoa repens extract for the treatment of patients with chronic prostatitis/chronic pelvic pain syndrome.Jan 15, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Urol. 2021 Jan 16. Epub 2021 Jan 16. PMID: 33452912
Article Published Date : Jan 15, 2021
Study Type : Human Study
Additional Links
Substances : Saw Palmetto
Diseases : Chronic Pelvic Pain Syndrome, Prostatitis: Chronic
[+]

The naturally occuring 5-alpha reductase inhibits Beta Sitosterol and Saw Palmetto are effective in treating androgenic alopecia. Apr 01, 2002

Pubmed Data : J Altern Complement Med. 2002 Apr;8(2):143-52. PMID: 12006122
Article Published Date : Apr 01, 2002
Study Type : Human Study
Additional Links
Substances : Beta Sitosterol, Saw Palmetto
Diseases : Alopecia: Androgenic
Pharmacological Actions : 5-alpha reductase inhibitor
[+]

The topical application of S. repens extract could be an alternative treatment in male pattern baldness in male patients.May 24, 2015

Pubmed Data : Australas J Dermatol. 2015 May 25. Epub 2015 May 25. PMID: 26010505
Article Published Date : May 24, 2015
Study Type : Human Study
Additional Links
Substances : Saw Palmetto
Diseases : Male Pattern Baldness
Additional Keywords : Plant Extracts, Significant Treatment Outcome
[+]

This study of Serenoa repens extract indicates the efficiency of this phytotherapeutic agent in patients with benign prostate hyperplasia.Aug 31, 2017

Pubmed Data : Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2017 Sep 1 ;38(2):123-129. PMID: 28991765
Article Published Date : Aug 31, 2017
Study Type : Human Study
Additional Links
Substances : Saw Palmetto
Diseases : Prostatic Hyperplasia: Benign
Additional Keywords : Plant Extracts
[+]

Combined Sabal and Urtica extracts exert anti-proliferative and anti-inflammatory effects in a model of benign prostate hyperplasia.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:311. Epub 2019 Mar 29. PMID: 30984003
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Nettle, Saw Palmetto
Diseases : Prostatic Hyperplasia
Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative
Additional Keywords : Plant Extracts
[+]

Crocus sativus, Serenoa repens and Pinus massoniana extracts modulate inflammatory response in isolated rat prostate challenged with LPS.Jun 30, 2017

Pubmed Data : J Biol Regul Homeost Agents. 2017 Jul-Sep,;31(3):531-541. PMID: 28889734
Article Published Date : Jun 30, 2017
Study Type : Animal Study
Additional Links
Substances : Pine Bark Extract, Saffron, Saw Palmetto
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Plant Extracts
[+]

Saw Palmetto (Serenoa repens) is more efficacious than Finasteride in inhibiting prostate enlargement.Apr 01, 2000

Pubmed Data : Prostate. 2000 Apr 1;43(1):49-58.PMID:10725865
Article Published Date : Apr 01, 2000
Study Type : Animal Study
Additional Links
Substances : Saw Palmetto
Diseases : Prostatic Hyperplasia: Benign
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Saw palmetto significantly alleviates urodynamic symptoms in hyperactive rat bladders. Apr 01, 2005

Pubmed Data : J Urol. 2005 Apr;173(4):1395-9. PMID: 15758812
Article Published Date : Apr 01, 2005
Study Type : Animal Study
Additional Links
Substances : Saw Palmetto
Diseases : Lower Urinary Tract Symptoms
Additional Keywords : Improved Micturition
[+]

Serenoa repens extracts promote hair regeneration and repair of hair loss.May 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Rev Med Pharmacol Sci. 2018 Jun ;22(12):4000-4008. PMID: 29949176
Article Published Date : May 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Saw Palmetto
Diseases : Hair Loss
Pharmacological Actions : Regenerative
Additional Keywords : Hair Regeneration
[+]

β-sitosterol enriched saw palmetto oil was efficacious in treating the benign prostatic hyperplasia complications.Oct 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2019 Oct 17 ;19(1):270. Epub 2019 Oct 17. PMID: 31623582
Article Published Date : Oct 16, 2019
Study Type : Animal Study
Additional Links
Substances : Beta Sitosterol, Saw Palmetto
Diseases : Prostatic Hyperplasia: Benign
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents
[+]

A comprehensive review of complementary and alternative treatments for alopecia. Jan 31, 2019

Pubmed Data : Skin Appendage Disord. 2019 Feb ;5(2):72-89. Epub 2018 Aug 21. PMID: 30815439
Article Published Date : Jan 31, 2019
Study Type : Review
Additional Links
Substances : Caffeine, Cystine, Melatonin, Methionine, Procyanidin B2 , Rosemary, Saw Palmetto, Vitamin B12, Vitamin C, Vitamin D, Zinc
Therapeutic Actions : Acupuncture, Magnet Therapy
[+]

A review of herbal preparations for the treatment of hair loss.Nov 02, 2019

Pubmed Data : Arch Dermatol Res. 2019 Nov 3. Epub 2019 Nov 3. PMID: 31680216
Article Published Date : Nov 02, 2019
Study Type : Review
Additional Links
Substances : Ginger, Ginseng, Ginseng (Korean), Pumpkin, Red Clover, Saw Palmetto
Diseases : Alopecia, Hair Loss
[+]

An overview of herbal alternatives in androgenetic alopecia.Apr 12, 2019

Pubmed Data : J Cosmet Dermatol. 2019 Apr 13. Epub 2019 Apr 13. PMID: 30980598
Article Published Date : Apr 12, 2019
Study Type : Review
Additional Links
Substances : Grape Seed Extract, Green Tea, Licorice, Rosemary, Saw Palmetto
Diseases : Androgenic Alopecia
[+]

Astaxanthin and saw palmetto extract decrease the growth of prostatic cancer cells via 5-alpha reductase inhibition. Jan 01, 2005

Pubmed Data : J Herb Pharmacother.2005;5(1):17-26. PMID: 16093232
 
Article Published Date : Jan 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Astaxanthin, Saw Palmetto
Diseases : Prostate Cancer
Pharmacological Actions : 5-alpha reductase inhibitor
[+]

Non-hormonal treatment for male infertility: the potential role of Serenoa repens, selenium and lycopene.Mar 31, 2019

Pubmed Data : Eur Rev Med Pharmacol Sci. 2019 Apr ;23(7):3112-3120. PMID: 31002161
Article Published Date : Mar 31, 2019
Study Type : Review
Additional Links
Substances : Lycopene, Saw Palmetto, Selenium
Diseases : Infertility: Male
Pharmacological Actions : Fertility Agents: Male
[+]

S. repens was generally well tolerated, and is a useful option for the treatment of symptomatic benign prostatic hyperplasia.. Feb 28, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drugs Aging. 2022 Mar ;39(3):235-243. Epub 2022 Mar 3. PMID: 35237936
Article Published Date : Feb 28, 2022
Study Type : Review
Additional Links
Substances : Saw Palmetto
Diseases : Prostatic Hyperplasia: Benign
Additional Keywords : Natural Substances Versus Drugs, Phytotherapy, Plant Extracts
[+]

Saw palmetto (Serenoa repens) induces growth arrest and apoptosis of human multiple myeloma cells. Aug 01, 2009

Pubmed Data : Oncol Rep. 2009 Aug;22(2):377-83. PMID: 19578780
Article Published Date : Aug 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Saw Palmetto
Diseases : Multiple Myeloma
[+]

Saw palmetto berry extract inhibits prostate cancer cell growth in part through Cox-2 enzyme inhibition. Jan 01, 2001

Pubmed Data : Cell Biol Int.2001;25(11):1117-24. PMID: 11913955
Article Published Date : Jan 01, 2001
Study Type : In Vitro Study
Additional Links
Substances : Saw Palmetto
Diseases : Prostate Cancer
Pharmacological Actions : Cyclooxygenase 2 Inhibitors
[+]

Saw palmetto extract at clinically relevant doses may exert a direct effect on the pharmacological receptors in the lower urinary tract, thereby improving urinary dysfunction in patients with benign prostatic hyperplasia and an overactive bladder.Apr 23, 2004

Pubmed Data : Life Sci. 2004 Apr 23;74(23):2897-908. PMID: 19262550
Article Published Date : Apr 23, 2004
Study Type : Commentary
Additional Links
Substances : Saw Palmetto
Diseases : Overactive Bladder, Prostatic Hyperplasia: Benign
Pharmacological Actions : 5-alpha reductase inhibitor, Adrenergic alpha-Antagonists, Cholinergic Antagonists
Additional Keywords : Plant Extracts
[+]

Saw palmetto extract has a broad range of therapeutic pharmacological actions relevant to benign prostatic hyperplasia. Apr 01, 2009

Pubmed Data : Biol Pharm Bull. 2009 Apr;32(4):646-50. PMID: 19336899
Article Published Date : Apr 01, 2009
Study Type : Review
Additional Links
Substances : Saw Palmetto
Diseases : Prostatic Hyperplasia: Benign
Pharmacological Actions : 5-alpha reductase inhibitor, Adrenergic alpha-Agonists, Calcium Channel Blockers
[+]

Saw palmetto has anticancer activity against a broad range of human cancer cell lines, with special efficacy against hormone-sensitive cancer cells. Mar 01, 2007

Pubmed Data : Anticancer Res.2007 Mar-Apr;27(2):873-81. PMID: 17465214
Article Published Date : Mar 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Saw Palmetto
Diseases : Breast Cancer, Cancers: All, Prostate Cancer
[+]

Saw palmetto induces programmed cell death in androgen-dependent prostate cancer cells. Sep 01, 2007

Pubmed Data : Int J Oncol.2007 Sep;31(3):593-600. PMID: 17671686
Article Published Date : Sep 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Saw Palmetto
Diseases : Prostate Cancer
[+]

Saw palmetto induces programmed cell death in human prostate cancer cells.May 01, 2009

Pubmed Data : BJU Int.2009 May;103(9):1275-83. Epub 2009 Jan 14 PMID: 19154468
Article Published Date : May 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Saw Palmetto
Diseases : Prostate Cancer
[+]

Serenoa repens and Urtica dioica fixed combination: In-vitro validation of a therapy for benign prostatic hyperplasia.Dec 01, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2020 Dec 2 ;21(23). Epub 2020 Dec 2. PMID: 33276425
Article Published Date : Dec 01, 2020
Study Type : In Vitro Study
Additional Links
Substances : Nettle, Saw Palmetto
Diseases : Prostatic Hyperplasia: Benign
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Interleukin-8 downregulation
[+]

Serenoa repens extract Permixon is considered to be a well-established medical use product for the symptomatic treatment of benign prostatic hyperplasia.Apr 30, 2018

Pubmed Data : Urologiia. 2018 May(2):114-120. PMID: 29901305
Article Published Date : Apr 30, 2018
Study Type : Review
Additional Links
Substances : Saw Palmetto
Diseases : Prostatic Hyperplasia: Benign
Additional Keywords : Plant Extracts
[+]

Serenoa repens extracts: In vitro study of the 5α-reductase activity in a co-culture model for benign prostatic hyperplasia.Sep 29, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Ital Urol Androl. 2018 Sep 30 ;90(3):199-202. Epub 2018 Sep 30. PMID: 30362688
Article Published Date : Sep 29, 2018
Study Type : In Vitro Study
Additional Links
Substances : Saw Palmetto
Diseases : Prostatic Hyperplasia: Benign
Pharmacological Actions : 5-alpha reductase inhibitor
[+]

Use of saw palmetto extract for benign prostatic hyperplasia.Nov 30, 2019

Pubmed Data : Food Sci Biotechnol. 2019 Dec ;28(6):1599-1606. Epub 2019 Apr 17. PMID: 31807332
Article Published Date : Nov 30, 2019
Study Type : Review
Additional Links
Substances : Saw Palmetto
Diseases : Prostatic Hyperplasia: Benign
Pharmacological Actions : Anti-Inflammatory Agents

Copyright: marilyna / 123RF Stock Photo

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BPH appears to be an inevitable consequence of ageing, affecting half of men by age 50 and up to 80% of men by age 80, but saw palmetto may help
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