Scopoletin

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36 Diseases Researched for Scopoletin

Name	AC	CK
Oxidative Stress	3	4
Fatty Liver	1	3
Hyperglycemia	2	3
Hyperlipidemia	1	3
Lipid Peroxidation	2	3
Acetaminophen (Tylenol) Toxicity	1	2
Alcohol Toxicity	1	2
Anxiety	1	2
Arthritis	1	2
Cancers: All	2	2
Diabetic Nephropathy	2	2
High Fat Diet	1	2
High Fructose Diet	1	2
Hyperuricemia	1	2
Inflammation	2	2
Intracerebral Hemorrhage	1	2
Kidney Damage: Drug-Induced	1	2
Liver Damage: Drug-Induced	1	2
Myocardial Infarction	1	2
Obesity	1	2
Aging	1	1
Aging Skin	1	1
Allergies	1	1
Asthma	1	1
Atopic Dermatitis	1	1
Cancers: Drug Resistant	1	1
Cancers: Multi-Drug Resistant	1	1
Carcinoma: Non-Small-Cell Lung	1	1
Coronavirus Disease (Covid-19)	1	1
Glomerulosclerosis	1	1
Insulin Disorders	1	1
Insulin Resistance	1	1
Liver Damage	1	1
Multiple Sclerosis	1	1
Neurological Conditions	1	1
Promyelocytic leukemia	1	1

31 Pharmacological Actions Researched for Scopoletin

Name	AC	CK
Anti-Inflammatory Agents	9	15
Antioxidants	6	9
NF-kappaB Inhibitor	4	6
Hepatoprotective	3	5
Hypolipidemic	2	5
Nrf2 activation	3	5
Interleukin-1 beta downregulation	2	4
Renoprotective	3	4
Tumor Necrosis Factor (TNF) Alpha Inhibitor	3	4
Antiproliferative	3	3
Cardioprotective	2	3
Hypoglycemic Agents	2	3
Alpha-glucosidase inhibitor	1	2
Anti-Apoptotic	2	2
Anxiolytic	1	2
Heme oxygenase-1 up-regulation	1	2
Interleukin-6 Downregulation	1	2
Neuroprotective Agents	1	2
Uricosuric Agents	1	2
Anti-Allergic Agents	1	1
Anti-Fibrotic	1	1
Antiviral Agents	1	1
Apoptotic	1	1
Immunomodulatory	1	1
Immunomodulatory: Th17 downregulation	1	1
Insulin Sensitizers	1	1
Insulin-releasing	1	1
Interleukin-1 alpha downregulation	1	1
Matrix metalloproteinase-1 (MMP-1) inhibitor	1	1
Pancreato Protective Agents	1	1
Transforming growth factor beta (TGF-β) inhibitor	1	1

Research Articles 27
Cumulative Knowledge Score 43
Overall Research Rating GOOD

View the Evidence:
27 Abstracts with Scopoletin Research

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View the Evidence: 27 Abstracts with Scopoletin Research

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Scopoletin ameliorates hyperlipidemia and hepatic steatosis.Dec 31, 2024

Ameliorate impacts of scopoletin against vancomycin-induced intoxication.Dec 31, 2021

Antihyperuricemic efficacy of Scopoletin-loaded Soluplus micelles in yeast extract/potassium oxonate-induced hyperuricemia.Aug 31, 2020

Cardioprotective role of scopoletin on isoproterenol-induced myocardial infarction.Jan 31, 2023

Scopoletin alleviates acetaminophen-induced hepatotoxicity.Jan 25, 2025

Scopoletin ameliorates anxiety-like behaviors in complete Freund’s adjuvant-induced mouse model.Feb 03, 2020

Scopoletin attenuates intracerebral hemorrhage-induced brain injury.Dec 31, 2020

Scopoletin improves glucose homeostasis.Mar 31, 2023

Scopoletin inhibits α-glucosidase in vitro and alleviates postprandial hyperglycemia in mice with diabetes.Sep 04, 2018

Scopoletin prevents alcohol-induced hepatic lipid accumulation by modulating the AMPK-SREBP pathway in diet-induced obese mice.Mar 31, 2014

Scopoletin suppresses IL-6 production from fibroblast-like synoviocytes of adjuvant arthritis.Nov 30, 2013

An overview of the pharmacological activities of scopoletin against different chronic diseases.Apr 30, 2022

Network pharmacology and molecular docking reveal the mechanism of Scopoletin against non-small cell lung cancer.Mar 31, 2021

Pharmacogenomics of scopoletin in tumor cells.Apr 14, 2016

Regulatory effects of Lycium barbarum extract and isolated scopoletin on atopic dermatitis-like skin inflammation.Dec 31, 2021

Scopoletin alleviates high glucose-induced toxicity in human renal proximal tubular cells.May 05, 2024

Scopoletin and umbelliferone from Cortex Mori as protective agents in high glucose-induced mesangial cell.Dec 31, 2020

Scopoletin attenuates allergy by inhibiting Th2 cytokines production in EL-4 T cells.Jul 31, 2012

Scopoletin could serve as a promising treatment of asthma. Dec 31, 2021

Scopoletin downregulates MMP‑1 expression in human fibroblasts via inhibition of p38 phosphorylation.Sep 30, 2018

Scopoletin has a potential activity for anti-aging via autophagy in human lung fibroblasts.Mar 14, 2015

Scopoletin increases glucose uptake through activation of PI3K and AMPK signaling pathway and improves insulin sensitivity in 3T3-L1 cells.Jan 31, 2020

Scopoletin induces apoptosis in human promyeloleukemic cells.Jun 30, 2005

Scopoletin protects INS-1 pancreatic β cells from glucotoxicity by reducing oxidative stress and apoptosis.Nov 30, 2023

Scopoletin stimulates the secretion of insulin.Aug 31, 2022

Scopoletin suppresses activation of dendritic cells and pathogenesis of experimental autoimmune encephalomyelitis.Dec 31, 2018

Targeting SIRT1 by scopoletin to inhibit XBB.1.5 COVID-19 life cycle.Dec 31, 2024

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Scopoletin

View the Evidence:
27 Abstracts with Scopoletin Research