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Seeds
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348 Diseases Researched for Seeds
Name
AC
CK
Focus
Hypertension
21
152
Oxidative Stress
42
125
Breast Cancer
30
117
Inflammation
20
109
Obesity
11
99
Diabetes Mellitus: Type 2
19
93
High Cholesterol
9
61
Cardiovascular Diseases
11
58
Insulin Resistance
7
56
Cancer Mortality
2
40
Asthma
8
37
Prostatic Hyperplasia: Benign
6
36
Rheumatoid Arthritis
6
35
Cholesterol: LDL/HDL ratio
5
34
Prostate Cancer
6
33
Triglycerides: Elevated
4
33
Constipation
4
32
Helicobacter Pylori Infection
5
32
Hot Flash
3
30
Osteoarthritis: Knee
3
30
Lipid Peroxidation
15
29
Dyslipidemias
7
27
Hyperglycemia
5
27
Hyperlipidemia
9
25
Breast Cancer: Prevention
4
24
HDL: Low
4
24
Hypoglycemia
3
23
Blood Pressure: High
2
22
Chemically-Induced Liver Damage
11
22
Metabolic Syndrome X
3
22
Cardiovascular Disease: Prevention
2
21
Allergic Rhinitis
2
20
C-Reactive Protein
2
20
Chemotherapy and Radiation Toxicity
6
20
Cholesterol: High
2
20
Colon Cancer
12
20
Diabetes: Cardiovascular Illness
2
20
Dry Skin
2
20
Dyspepsia
2
20
Hashimoto's thyroiditis
2
20
Kidney Failure
1
20
Mastalgia
2
20
Nonalcoholic fatty liver disease (NAFLD)
2
20
Osteoarthritis
2
20
Overweight
1
20
Liver Cancer
11
19
Atherosclerosis
5
18
Chemotherapy-Induced Toxicity: Cisplatin
9
18
Memory Disorders
6
18
Cognitive Decline/Dysfunction
4
16
Diabetic Nephropathy
4
16
Infertility: Male
4
16
Menopausal Syndrome
4
16
Wound Healing
4
16
Polycystic Ovary Syndrome
3
15
Testosterone: Too High
3
15
Diabetes: Oxidative Stress
7
14
Diabetic Complications
8
14
Sperm Quality: Low
3
14
Drug-Induced Toxicity: Methotrexate
3
13
Kidney Stones
3
13
Postmenopausal Disorders
3
13
Acetaminophen (Tylenol) Toxicity
6
12
Aging Skin
2
12
Bone Diseases
2
12
Chemical Weapon Agent Injury
2
12
Diabetes: Glycation/A1C
2
12
Fatigue
2
12
Lipopolysaccharide-Induced Toxicity
7
12
Lupus Nephritis
2
12
Metabolic Diseases
2
12
Rhinosinusitis
2
12
Cancers: All
11
11
Cholesterol: Oxidation
2
11
Hepatitis C
2
11
A1C
1
10
Acute lymphoblastic leukemia (ALL)
1
10
Anemia: Iron Deficiency
1
10
Anti-Social Behavior
1
10
Anxiety Disorders
1
10
Appetite Disorders
1
10
Athletic Performance
1
10
Attention Deficit Disorder with Hyperactivity
1
10
Bladder Stones
1
10
Blepharitis
1
10
Blood Viscosity: Elevated
1
10
Carpal Tunnel Syndrome
1
10
Chemotherapy-Induced Toxicity: Gentamicin
5
10
Chronic Fatigue Syndrome
1
10
Dental Plaque
1
10
Diabetes Mellitus: Type 1
5
10
Diabetic Ulcer
1
10
Dysmenorrhea
1
10
Elevated CRP
1
10
Eosinophilia
1
10
Epilepsy: Childhood
1
10
Estrogen Deficiency
1
10
Hemodialysis
1
10
Hyperviscosity Syndrome
1
10
Incontinence: Urinary
1
10
Insomnia
1
10
Kidney Failure: Acute
1
10
Liver Fibrosis
1
10
Liver Steatosis
1
10
Meibomian gland dysfunction
1
10
Multiple Sclerosis: Relapsing-Remitting
1
10
Muscle Damage: Exercise-Induced
1
10
Neurodegenerative Diseases
8
10
Omega-3 Fatty Acid Deficiency
1
10
Opiate Addiction/Withdrawal
1
10
Overactive Bladder
1
10
Peripheral Arterial Disease
1
10
Pharyngitis
1
10
Phobia: Social
1
10
Prenatal Herb Exposure
1
10
Prostate Cancer: Prevention
1
10
Prostate: PSA Doubling
1
10
Sickle Cell Anemia
1
10
Skin Diseases
1
10
Tonsillitis
1
10
Vaccine-induced Toxicity
1
10
Vitiligo
1
10
Weight Probems: Appetite
1
10
Cervical Cancer
3
8
Ischemia
5
8
Kidney Damage
5
8
Lead Poisoning
4
8
Multiple Sclerosis
5
8
Osteoporosis
4
8
Staphylococcus aureus infection
7
7
Adiponectin: Low Levels
3
6
Advanced Glycation End products (AGE)
3
6
Alcohol Toxicity
3
6
Arteriosclerosis
2
6
Endothelial Dysfunction
3
6
Escherichia coli Infections
6
6
Fungal Infection
5
6
Hydrogen Peroxide Induced Toxicity
2
6
Hyperinsulinism
3
6
Lung Cancer
4
6
Morphine Tolerance/Dependence
4
6
Pain
4
6
Polycystic Kidney Diseases
3
6
Pulmonary Fibrosis: Bleomycin-Induced
3
6
Staphylococcus aureus: Methicillin-resistant (MRSA)
2
6
Alzheimer's Disease
5
5
Arthritis
3
5
Fibrosis
3
5
Gastric Ulcer
3
5
Ovarian Cancer
3
5
Brain: Oxidative Stress
2
4
Breast Cancer: Chemically-Induced
2
4
Cadmium Poisoning
2
4
Cerebral Ischemia
2
4
Chemotherapy-Induced Toxicity: Cyclophosphamide
2
4
Chronic Pain
2
4
Colitis
2
4
Epilepsy
3
4
Fatty Liver
2
4
Gastritis
2
4
High Fat Diet
2
4
Hypercholesterolemia
2
4
Hypothyroidism
2
4
Immune Disorders: Low Immune Function
2
4
Kidney Cancer
2
4
Liver Damage
3
4
Parasitic Intestinal Diseases
2
4
Prostatic Hyperplasia, Testosterone-Induced
2
4
Salmonella Infections
4
4
Schistosomiasis
2
4
Seizures
2
4
Stress
2
4
Toxoplasma gondii Infection
2
4
Toxoplasmosis
2
4
Bacillus Cereus infection
3
3
Brain Inflammation
2
3
Chemotherapy-Induced Toxicity: Doxorubicin
2
3
DNA damage
2
3
Depression
2
3
Gastric Cancer
2
3
Gram-Negative Bacterial Infections
3
3
Gram-Positive Bacterial Infections
3
3
HIV Infections
1
3
Kidney Diseases
2
3
Pancreatic Cancer
3
3
Parkinson's Disease
3
3
Stomach Cancer
2
3
Streptococcus pneumoniae infection
2
3
Thrombosis
2
3
Abdominal Adhesions
1
2
Abdominal Obesity (Midsection Fat)
1
2
Aflatoxicosis
1
2
Aging
1
2
Allergies
2
2
Anxiety
1
2
Aortic Plaques
1
2
Arterial Plaque
1
2
Aspirin-Induced Toxicity
1
2
Asthenozoospermia
1
2
Asthma: Bronchial
2
2
Bacillus subtilis infections
2
2
Bacterial Infections: Resistance/Biofilm Formation
2
2
Bee Colony Collapse
1
2
Benzo[a]pyrene-induced Toxicity
1
2
Bisphenol Toxicity
1
2
Brain Damage
1
2
Breast Cancer: Conventional Treatment
1
2
Burns
1
2
Cancer Metastasis
2
2
Cancers: Radiation-Induced
1
2
Candida Infection
2
2
Candidiasis
1
2
Cataract
1
2
Cataract: Radiation-Induced
1
2
Central Nervous System Diseases
2
2
Cerebral Hypoperfusion
1
2
Chemotherapy-Induced Toxicity: Bleomycin
1
2
Chemotherapy-Induced Toxicity: Kidney
1
2
Chemotherapy-Induced Toxicity: Tamoxifen
1
2
Cholestasis
1
2
Clogged Arteries
1
2
Colon Cancer: Prevention
1
2
Copper Toxicity
1
2
Corticosteroid-Induced Toxicity
1
2
Cytomegalovirus Infections
1
2
Dementia
1
2
Depression: Postpartum
1
2
Diabetes Mellitus: Type 1: Prevention
1
2
Diabetes Mellitus: Type 2: Prevention
1
2
Diabetes: Gestational
1
2
Diabetes: Lipids/Cholesterol
1
2
Diabetic Microangiopathy
1
2
Diabetic Neuropathies
1
2
Diabetic Neuropathy
1
2
Diarrhea
1
2
Drug Toxicity: Methotrexate
1
2
Drug-Induced Toxicity
1
2
Drug-Induced Toxicity: Cyclosporine
1
2
Drug-Induced Toxicity: Gastrointestinal
1
2
Encephalomyelitis
1
2
Estrogen Dysregulation: 2/4/16 hydroxyestrone ratios
1
2
Fatigue: Excercise-Induced
1
2
Food Allergies
1
2
Formaldehyde Toxicity
1
2
Fructose-Induced Toxicity
1
2
Gastrointestinal Hemorrhage
1
2
HIV Drug-Induced Toxicity
1
2
Hearing Loss: Noise-Induced
1
2
Heart Failure
1
2
Helminthiasis
1
2
High Fructose Diet
1
2
High Homocysteine
1
2
Hypoxia
1
2
Inflammatory Bowel Diseases
1
2
Intestinal Cancer
1
2
Intestinal Ischemia
1
2
Keratitis
1
2
Kidney Cancer: Prevention
1
2
Kidney Damage: Chemically-Induced
1
2
Kidney Damage: Drug-Induced
1
2
Kidney Fibrosis
1
2
Klebsiella Infections
2
2
Learning disorders
1
2
Liver Damage: Aflatoxin-Induced
1
2
Low Immune Function: Splenic Dysfunction
1
2
Lung Damage
1
2
MRSA
2
2
Melanoma
1
2
Memory Disorders: Drug-Induced
1
2
Memory Loss
1
2
Mucosal Damage: Radiation Induced
1
2
Myocardial Fibrosis
1
2
Osteopenia
1
2
Ovarian Failure
1
2
Ovariectomy Associated Adverse Changes
1
2
Pesticide Toxicity
1
2
Phthalate Toxicity
1
2
Postmenopausal Disorder: Brain/Nervous System Pathology
1
2
Prenatal Chemical Exposures
1
2
Protein Malnourishment
1
2
Proteinuria
1
2
Radiation Disaster Associated Toxicity
1
2
Radiation Induced Illness: Mucositis
1
2
Radiation Induced Illness: Thoracic
1
2
Radiation-induced illness: Lung
1
2
Skin Cancer
1
2
Sodium nitrate toxicity
1
2
Space Flight Associated Adverse Changes
1
2
Spinal Cord Injuries
1
2
Squamous cell carcinoma
1
2
Streptococcus Infections
1
2
Tapeworm Infection
1
2
Traumatic Brain Injury
2
2
Ulcerative Colitis
1
2
Urolithiasis
1
2
Wound Healing: Delayed
1
2
Acne
1
1
Atopic Dermatitis
1
1
Autoimmune Diseases
1
1
Bacterial Infections
1
1
Blastocystis hominis infections
1
1
Brain Ischemia
1
1
Breast Cancer: Triple Negative
1
1
Breast Milk: Inadequate/Poor Quality
1
1
Campylobacter Infections
1
1
Chemotherapy-Induced Kidney Damage
1
1
Choriocarcinoma
1
1
Chronic Obstructive Pulmonary Disease
1
1
Clostridium Infections
1
1
Cough
1
1
Dental Caries
1
1
Dermatophyte Infections
1
1
Diabetes
1
1
Enterococcus Infections
1
1
Food Poisoning
1
1
Foodborne Pathogens: Prevention/Food Preservation
1
1
Gingivitis
1
1
Hepatic Steatosis
1
1
Histamine: Elevated
1
1
Hodgkin Lymphoma
1
1
Hypersensitivity: Respiratory
1
1
Hypotension
1
1
Infection: Antibiotic Resistant
1
1
Influenza A
1
1
Leishmaniasis
1
1
Leukemia
1
1
Listeria Infections
1
1
Liver Cancer: Prevention
1
1
Liver Disease
1
1
Liver Diseases
1
1
Lung Diseases
1
1
Lymphoma
1
1
Micrococcus luteus infections
1
1
Multiple Myeloma
1
1
Nephrolithiasis
1
1
Neurotoxicity
1
1
Premenstrual syndrome
1
1
Pseudomonas aeruginosa
1
1
Pulmonary Emphysema
1
1
Radiation Induced Illness: Immune Suppression
1
1
Respiratory Diseases
1
1
Rheumatism
1
1
Skin Diseases: Fungal
1
1
Trophoblastic Neoplasms
1
1
Trophoblastic Tumor
1
1
Ulcers
1
1
Vibrio Infections
1
1
Epstein-Barr Virus Infections
1
0
122 Pharmacological Actions Researched for Seeds
Name
AC
CK
Focus
Antioxidants
95
226
Hypoglycemic Agents
25
165
Anti-Inflammatory Agents
50
159
Hypolipidemic
25
120
Antihypertensive Agents
16
115
Chemopreventive
25
92
Tumor Necrosis Factor (TNF) Alpha Inhibitor
14
68
Hepatoprotective
25
66
Antiproliferative
28
65
Neuroprotective Agents
29
61
Anticholesteremic Agents
10
60
Malondialdehyde Down-regulation
19
54
Chemoprotective Agents
19
45
Cardioprotective
12
44
Apoptotic
21
40
Hypotensive
3
40
Immunomodulatory
10
40
Interleukin-6 Downregulation
9
40
Anti-Bacterial Agents
15
37
Renoprotective
18
33
Superoxide Dismutase Up-regulation
12
31
Analgesics
9
30
Anticarcinogenic Agents
14
24
Bronchodilator Agents
3
22
Anti Inflammatory
1
20
Anti-Ulcer Agents
7
20
Laxative
2
20
NF-kappaB Inhibitor
9
20
anti-inflammatory
2
20
Gastroprotective
10
19
Radioprotective
10
19
Anti-Fibrotic
5
18
Insulin Sensitizers
4
16
Chemotherapeutic
5
14
Osteoprotective
3
14
Vascular Endothelial Growth Factor A Inhibitor
3
14
Anti-Apoptotic
8
13
Antinoceceptive
3
13
Antineoplastic Agents
5
12
Vascular Endothelial Growth Factor Inhibitors
2
12
Antimicrobial
11
11
Enzyme Inhibitors
2
11
Antifungal Agents
9
10
Anxiolytic
1
10
Cytoprotective
5
10
Fertility Agents: Male
1
10
Insulin Down-Regulation
1
10
Interleukin 1 receptor antagonist (IL-1Ra) up-regulation
1
10
Tumor Suppressor Protein p53 Upregulation
5
10
Antiparasitic Agents
5
8
Antiviral Agents
5
8
Cyclooxygenase 2 Inhibitors
6
8
Interleukin-1 beta downregulation
5
8
Pancreato Protective Agents
4
8
Anti-metastatic
6
7
Nitric Oxide Inhibitor
4
7
Anticonvulsants
4
6
Cell cycle arrest
5
6
Antidepressive Agents
3
5
Caspase-3 Activation
1
5
Caspase-8 activation
1
5
Caspase-9 Activation
1
5
Cyclooxygenase 1 Inhibitor
3
5
Angiogenesis Inhibitors
3
4
Catalase Up-Regulation
2
4
Gastrointestinal Agents
3
4
Genoprotective
2
4
Prophylactic Agents
2
4
Anti-Platelet
2
3
Acetylcholinesterase Inhibitor
1
2
Analgesics: Non-Narcotic
1
2
Anti-Adipogenic
1
2
Anti-Anxiety Agents
1
2
Anti-Glycation Agents
1
2
Anti-atherogenic
1
2
Anti-thrombotic
1
2
Anticholinergic
1
2
Bcl-2 protein down-regulation
2
2
Brain-derived neurotrophic factor modulator
1
2
Cardiovascular Agents
1
2
Contraceptive Agents: Male
1
2
Cyclin D1 Down-Regulation
1
2
Cyclooxygenase Inhibitors
1
2
Epidermal growth factor receptor (EGFR) inhibitor
1
2
Gluconeogenesis Inhibitor
1
2
Heme oxygenase-1 up-regulation
1
2
Histamine Antagonists
1
2
Histamine down-regulation
2
2
Immunomodulatory: Th17 downregulation
1
2
Insulin-releasing
1
2
Interferon Inducers
1
2
MicroRNA modulator
1
2
Phase II Detoxification Enzyme Inducer
1
2
Photoprotective
1
2
Platelet Aggregation Inhibitors
1
2
Regenerative
1
2
Remyelination
1
2
STAT3 Inhibitor
2
2
Selective Estrogen Receptor Modulators
1
2
Selective estrogen enzyme modulator (SEEM)
1
2
Vasodilator Agents
1
2
5-Lipoxygenase Inhibitor
1
1
Anti-Allergic Agents
1
1
Anti-Angiogenic
1
1
Anti-Asthmatic Agents
1
1
Anti-Proliferative
1
1
Antimutagenic Agents
1
1
Antispasmodic
1
1
Antitussive Agents
1
1
Aromatase Inhibitors
1
1
Chemosensitizer
1
1
Cytotoxic
1
1
Enzyme Inhibitors: Pancreatic Amylase
1
1
Galactogogue
1
1
Heme oxygenase-1 inducer
1
1
Interleukin-8 downregulation
1
1
Leishmanicidal
1
1
Leukotriene Antagonists
1
1
Leukotriene D4 antagonist
1
1
Nrf2 activation
1
1
Postaglandin PGE2 downregulation
1
1
Viral Hemagglutinin Inhibitor
1
1
Research Articles
532
Cumulative Knowledge Score
860
Overall Research Rating
EXCELLENT
Related Topics
The Following are Sub-Topics of Seeds
Sunflower Seeds
Flaxseed
Celery seed
Pumpkin Seed Oil/Meal
Hemp Seed
Sesame Seeds
Nigella sativa (aka Black Seed)
Cumin
View the Evidence:
652 Abstracts with Seeds Research
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[+]
A systematic review and meta-analysis of the effect of Nigella sativa supplementation on obesity indices.
May 31, 2018
Click here to read the entire abstract
Pubmed Data
: Complement Ther Med. 2018 Jun ;38:48-57. Epub 2018 Apr 11. PMID:
29857879
Article Published Date
: May 31, 2018
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Obesity
Additional Keywords
:
Anti-Obesity Agents
[+]
Current findings suggest N. sativa supplementation a suitable choice in managing the complications of T2D.
Nov 30, 2017
Click here to read the entire abstract
Pubmed Data
: Complement Ther Med. 2017 Dec ;35:6-13. Epub 2017 Aug 30. PMID:
29154069
Article Published Date
: Nov 30, 2017
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Hypoglycemic Agents
,
Hypolipidemic
[+]
Effects of Nigella sativa on glycemic control, lipid profiles, and biomarkers of inflammatory and oxidative stress.
May 10, 2020
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2020 May 11. Epub 2020 May 11. PMID:
32394508
Article Published Date
: May 10, 2020
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Hyperglycemia
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticholesteremic Agents
,
Hypoglycemic Agents
,
Hypolipidemic
[+]
Flax and Breast Cancer: A Systematic Review.
Sep 07, 2013
Click here to read the entire abstract
Pubmed Data
: Integr Cancer Ther. 2013 Sep 8. Epub 2013 Sep 8. PMID:
24013641
Article Published Date
: Sep 07, 2013
Study Type
: Meta Analysis
Additional Links
Substances
:
Flaxseed
Diseases
:
Breast Cancer
,
Cancer Mortality
Pharmacological Actions
:
Chemopreventive
[+]
Flax and Breast Cancer: A Systematic Review.
Sep 07, 2013
Click here to read the entire abstract
Pubmed Data
: Integr Cancer Ther. 2013 Sep 8. Epub 2013 Sep 8. PMID:
24013641
Article Published Date
: Sep 07, 2013
Study Type
: Meta Analysis
Additional Links
Substances
:
Flaxseed
Diseases
:
Breast Cancer
,
Cancer Mortality
Pharmacological Actions
:
Chemopreventive
[+]
Flaxseed significantly reduced circulating concentrations of high-sensitivity-CRP and TNFα.
May 21, 2019
Click here to read the entire abstract
Pubmed Data
: Adv Nutr. 2019 May 22. Epub 2019 May 22. PMID:
31115436
Article Published Date
: May 21, 2019
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Flaxseed
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Flaxseed supplementation improves serum total cholesterol, triglyceride, and LDL-C, which could delay the progression of heart disease.
Dec 29, 2019
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2019 Dec 30 ;152:104622. Epub 2019 Dec 30. PMID:
31899314
Article Published Date
: Dec 29, 2019
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Flaxseed
Diseases
:
Heart Disease
Pharmacological Actions
:
Cardioprotective
,
Hypolipidemic
[+]
Flaxseed supplementation may improve some circulating concentrations of specific adhesion molecules and inflammatory cytokines.
Nov 14, 2019
Click here to read the entire abstract
Pubmed Data
: Cytokine. 2019 Nov 15 ;126:154922. Epub 2019 Nov 15. PMID:
31739218
Article Published Date
: Nov 14, 2019
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Flaxseed
Diseases
:
Endothelial Dysfunction
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Meta-analysis: Flaxseed consumption may reduce blood pressure
Mar 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2015 Apr ;145(4):758-65. Epub 2015 Mar 4. PMID:
25740909
Article Published Date
: Mar 31, 2015
Study Type
: Meta Analysis
Additional Links
Substances
:
Flaxseed
Diseases
:
Blood Pressure: High
,
Hypertension
Pharmacological Actions
:
Hypotensive
[+]
N. sativa consumption has a significant lowering effect on glycemic status.
Mar 13, 2019
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2019 Mar 14. Epub 2019 Mar 14. PMID:
30873688
Article Published Date
: Mar 13, 2019
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Hyperglycemia
Pharmacological Actions
:
Hypoglycemic Agents
[+]
Nigella Sativa has a significant impact on plasma lipid concentrations, leading to lower total cholesterol.
Feb 09, 2016
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2016 Feb 10. Epub 2016 Feb 10. PMID:
26875640
Article Published Date
: Feb 09, 2016
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Cardiovascular Disease: Prevention
,
High Cholesterol
,
Triglycerides: Elevated
Pharmacological Actions
:
Anticholesteremic Agents
[+]
Nigella sativa supplementation may provide additional benefits for the treatment of asthma.
Nov 28, 2019
Click here to read the entire abstract
Pubmed Data
: Am J Emerg Med. 2019 Nov 29. Epub 2019 Nov 29. PMID:
31892440
Article Published Date
: Nov 28, 2019
Study Type
: Meta Analysis
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Asthma
Pharmacological Actions
:
Anti-Asthmatic Agents
[+]
Sesame consumption can reduce systolic and diastolic blood pressure.
Jul 31, 2017
Click here to read the entire abstract
Pubmed Data
: J Sci Food Agric. 2017 Aug ;97(10):3087-3094. Epub 2017 May 12. PMID:
28387047
Article Published Date
: Jul 31, 2017
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Sesame Seeds
Diseases
:
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
[+]
Supplementation with N. sativa exerts a moderate effect on reduction in body weight, body mass index and waist circumference.
Mar 16, 2018
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2018 Mar 17. Epub 2018 Mar 17. PMID:
29559374
Article Published Date
: Mar 16, 2018
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Obesity
Additional Keywords
:
Anti-Obesity Agents
[+]
This meta-analysis of RCTs showed significant reductions in both SBP and DBP following supplementation with various flaxseed products.
May 31, 2016
Click here to read the entire abstract
Pubmed Data
: Clin Nutr. 2016 Jun ;35(3):615-25. Epub 2015 May 29. PMID:
26071633
Article Published Date
: May 31, 2016
Study Type
: Meta Analysis
Additional Links
Substances
:
Flaxseed
Diseases
:
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
Additional Keywords
:
Plant Extracts
[+]
This meta-analysis suggests that Nigella sativa supplementation in humans may benefit as an antioxidant.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: ScientificWorldJournal. 2020 ;2020:2390706. Epub 2020 May 6. PMID:
32454800
Article Published Date
: Dec 31, 2019
Study Type
: Meta Analysis
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
This meta-analysis suggests that short-term treatment with N. sativa powder can significantly reduce SBP and DBP levels.
Aug 09, 2016
Click here to read the entire abstract
Pubmed Data
: J Hypertens. 2016 Aug 10. Epub 2016 Aug 10. PMID:
27512971
Article Published Date
: Aug 09, 2016
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
[+]
This meta-analysis suggests thatN. sativa seed and seed oil supplementation can significantly reduce serum CRP level.
Jul 31, 2019
Click here to read the entire abstract
Pubmed Data
: Complement Ther Med. 2019 Aug ;45:149-155. Epub 2019 Jun 14. PMID:
31331553
Article Published Date
: Jul 31, 2019
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
C-Reactive Protein (CRP)
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
This systematic review and meta-analysis suggested the efficacy of cumin supplementation on lipid parameters.
Oct 31, 2018
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2018 Nov ;32(11):2146-2154. Epub 2018 Aug 8. PMID:
30088304
Article Published Date
: Oct 31, 2018
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Cumin
Diseases
:
Dyslipidemias
,
Hyperlipidemia
Pharmacological Actions
:
Hypolipidemic
Additional Keywords
:
Phytotherapy
[+]
Whole flaxseed has significant effects on improving glycemic control.
Jan 31, 2018
Click here to read the entire abstract
Pubmed Data
: Nutr Rev. 2018 Feb 1 ;76(2):125-139. PMID:
29228348
Article Published Date
: Jan 31, 2018
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Flaxseed
Diseases
:
Hypoglycemia
,
Insulin Resistance
Pharmacological Actions
:
Hypoglycemic Agents
[+]
Whole flaxseed is a good choice for weight management particularly for weight reduction in overweight and obese participants.
Jun 20, 2017
Click here to read the entire abstract
Pubmed Data
: Obes Rev. 2017 Jun 21. Epub 2017 Jun 21. PMID:
28635182
Article Published Date
: Jun 20, 2017
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Flaxseed
Diseases
:
Obesity
,
Overweight
Additional Keywords
:
Anti-Obesity Agents
,
flaxseed
,
obesity
,
overweight
[+]
A dietary mixture of sesame, pumpkin and flax seed added to a habitual diet lowered triglyceride and CRP, TNF-alpha, IL-6 levels
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: ScientificWorldJournal. 2014 ;2014:563576. Epub 2014 Jan 22. PMID:
24578648
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
,
Pumpkin Seeds
,
Sesame Seeds
Diseases
:
Inflammation
,
Kidney Failure
Pharmacological Actions
:
Anti Inflammatory
,
Hypoglycemic Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Supplementation
[+]
A flaxseed-derived lignan supplement has therapeutic value in type 2 diabetics.
Nov 07, 2007
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2007 Nov 7;2(11):e1148. PMID:
17987126
Article Published Date
: Nov 07, 2007
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
,
Lignans
Diseases
:
Diabetes Mellitus: Type 2
[+]
A flaxseed-derived lignan supplement may reduce C-reactive protein in type 2 diabetics.
Apr 01, 2009
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2009 Apr;101(8):1145-9. PMID:
18775100
Article Published Date
: Apr 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Diabetes: Cardiovascular Illness
,
Elevated CRP
[+]
A hemp seed containing proprietary Chinese herbal medicine alleviates symptoms of functional constipation.
Nov 02, 2010
Click here to read the entire abstract
Pubmed Data
: Am J Gastroenterol. 2010 Nov 2. Epub 2010 Nov 2. PMID:
21045817
Article Published Date
: Nov 02, 2010
Study Type
: Human Study
Additional Links
Substances
:
Hemp Seed
Diseases
:
Constipation
[+]
A mix of pumkin Seed, horsetail and flax is highly effective on stress urinary incontinence.
Mar 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Tradit Complement Med. 2019 Apr ;9(2):138-142. Epub 2018 May 3. PMID:
30963048
Article Published Date
: Mar 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
,
Horsetail
,
Pumpkin Seeds
Diseases
:
Incontinence: Urinary
Additional Keywords
:
Significant Treatment Outcome
[+]
A randomized controlled trial of a herbal compound for improving metabolic parameters in diabetic patients with uncontrolled dyslipidemia.
Feb 05, 2019
Click here to read the entire abstract
Pubmed Data
: Endocr Metab Immune Disord Drug Targets. 2019 Feb 6. Epub 2019 Feb 6. PMID:
30727929
Article Published Date
: Feb 05, 2019
Study Type
: Human Study
Additional Links
Substances
:
Aloe Vera
,
Fenugreek
,
Milk Thistle
,
Nigella sativa (aka Black Seed)
,
Psyllium
Diseases
:
Diabetes Mellitus: Type 2
,
Dyslipidemias
Pharmacological Actions
:
Hypolipidemic
[+]
Addition of flaxseed to yogurt can be effective in the management of type 2 diabetes.
Sep 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Clin Nutr Res. 2019 Oct ;8(4):284-295. Epub 2019 Oct 2. PMID:
31720254
Article Published Date
: Sep 30, 2019
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
,
Yoghurt
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anticholesteremic Agents
,
Hypoglycemic Agents
[+]
Adherence to a diet comprising mostly fruits, vegetables, fish, and olive/sunflower oil, along with avoidance of Western-type foods, may contribute to a substantial reduction in postmenopausal breast cancer risk.
Nov 15, 2009
Click here to read the entire abstract
Pubmed Data
: Am J Epidemiol. 2009 Nov 15;170(10):1257-67. Epub 2009 Oct 14. PMID:
19828509
Article Published Date
: Nov 15, 2009
Study Type
: Human Study
Additional Links
Substances
:
Fruit: All
,
Olive
,
Sunflower Seeds
,
Vegetables: All
Diseases
:
Breast Cancer
Therapeutic Actions
:
Dietary Modification: Non-Western Diet
Additional Keywords
:
Risk Reduction
[+]
After treatment the severity of burning mouth syndrome symptoms decreased.
Aug 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Altern Complement Med. 2020 Sep ;26(9):799-806. PMID:
32924561
Article Published Date
: Aug 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Chamomile
,
Flaxseed
Diseases
:
Burning Mouth Syndrome
[+]
An herbal combination of saffron, celery seed and anise is more effective than the drug mefenamic acid (NSAID) in relieving menstrual pain.
Sep 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Midwifery Womens Health. 2009 Sep-Oct;54(5):401-4. PMID:
19720342
Article Published Date
: Sep 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Anise
,
Celery seed
,
Saffron
Diseases
:
Dysmenorrhea
Additional Keywords
:
Superiority of Natural Substances versus Drugs
[+]
Black cumin (Nigella sativa) and Phyllanthus niruri provide symptomatic relief in the treatment of acute tonsillo-pharyngitis patients.
Jun 01, 2008
Click here to read the entire abstract
Pubmed Data
: Int J Clin Pharmacol Ther. 2008 Jun;46(6):295-306. PMID:
18541126
Article Published Date
: Jun 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
,
Phyllanthus niruri (Stonebreaker)
Diseases
:
Pharyngitis
,
Tonsillitis
Additional Keywords
:
Plant Extracts
[+]
Black cumin (Nigella sativa) has a prophylactic effect on chemical war victims.
Nov 01, 2008
Click here to read the entire abstract
Pubmed Data
: J Altern Complement Med. 2008 Nov;14(9):1137-44. PMID:
18991514
Article Published Date
: Nov 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Chemical Weapon Agent Injury
[+]
Black cumin (Nigella sativa) is effective in long-term treatment of opioid dependence.
Apr 01, 2008
Click here to read the entire abstract
Pubmed Data
: J Ayub Med Coll Abbottabad. 2008 Apr-Jun;20(2):118-24. PMID:
19385474
Article Published Date
: Apr 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Opiate Addiction/Withdrawal
[+]
Black cumin alleviates symptoms of allergic rhinitis.
Oct 12, 2010
Click here to read the entire abstract
Pubmed Data
: Am J Otolaryngol. 2010 Oct 12. Epub 2010 Oct 12. PMID:
20947211
Article Published Date
: Oct 12, 2010
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Allergic Rhinitis
[+]
Black cumin possesses clinical useful anti-H. pylori activity compared to triple therapy.
Jul 01, 2010
Click here to read the entire abstract
Pubmed Data
: Saudi J Gastroenterol. 2010 Jul-Sep;16(3):207-14. PMID:
20616418
Article Published Date
: Jul 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Dyspepsia
,
Helicobacter Pylori Infection
Pharmacological Actions
:
Anti-Bacterial Agents
,
Anti-Ulcer Agents
Additional Keywords
:
Drug: Amoxicillin
,
Drug: Omeprazole
,
Drug-Plant-Vitamin Synergies
,
Natural Substances Versus Drugs
,
Plant Extracts
[+]
Black cumin seeds decreased Methotrexate hepatotoxicity and improved survival in children with ALL
Mar 19, 2015
Click here to read the entire abstract
Pubmed Data
: Infect Disord Drug Targets. 2015 Mar 20. Epub 2015 Mar 20. PMID:
25809628
Article Published Date
: Mar 19, 2015
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Acute lymphoblastic leukemia (ALL)
,
Drug-Induced Toxicity: Methotrexate
Pharmacological Actions
:
Chemotherapeutic
,
Hepatoprotective
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Black cumin seeds have significant anti-diabetic effects in type 2 diabetics.
Oct 01, 2010
Click here to read the entire abstract
Pubmed Data
: Indian J Physiol Pharmacol. 2010 Oct-Dec;54(4):344-54. PMID:
21675032
Article Published Date
: Oct 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
A1C
,
Diabetes: Glycation/A1C
,
Diabetes Mellitus: Type 2
,
Insulin Resistance
Pharmacological Actions
:
Hypoglycemic Agents
,
Insulin Sensitizers
Additional Keywords
:
Beta Cell Protection
,
Beta Cell Regeneration
[+]
Black cumin seeds improves serum lipids, atherogenic index of plasma and modulates anthropometric features in patients with Hashimoto's thyroiditis.
Mar 26, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Lipids Health Dis. 2018 Mar 27 ;17(1):59. Epub 2018 Mar 27. PMID:
29587770
Article Published Date
: Mar 26, 2018
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Hashimoto's thyroiditis
Pharmacological Actions
:
Hypolipidemic
[+]
Both flaxseed and psyllium may decrease constipation symptoms, weight, glycemic and lipid levels, with flaxseed appearing to be superior to psyllium.
Jan 31, 2019
Click here to read the entire abstract
Pubmed Data
: Clin Nutr ESPEN. 2019 Feb ;29:41-48. Epub 2018 Nov 17. PMID:
30661699
Article Published Date
: Jan 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
,
Psyllium
Diseases
:
Constipation
,
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Hypoglycemic Agents
,
Hypolipidemic
,
Laxative
Additional Keywords
:
Anti-Obesity Agents
[+]
CBD enriched hemp oil could be beneficial in girls with adverse drug effects following human papillomavirus (HPV) vaccine.
Jan 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Isr Med Assoc J. 2017 Feb ;19(2):79-84. PMID:
28457055
Article Published Date
: Jan 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Hemp Seed
Diseases
:
Vaccine-induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antinoceceptive
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
Anti Therapeutic Actions
:
Vaccination: HPV (Gardasil)
[+]
Chia and flaxseeds display significant hypoglycemic activity.
Jan 01, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Clin Nutr. 2017 02 ;71(2):234-238. Epub 2016 Dec 21. PMID:
28000689
Article Published Date
: Jan 01, 2017
Study Type
: Human Study
Additional Links
Substances
:
Chia
,
Flaxseed
Pharmacological Actions
:
Hypoglycemic Agents
[+]
Co-administration of flaxseed and hesperidin appears to be superior to either supplementation alone on metabolic syndrome treatment.
Apr 14, 2020
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2020 Apr 15. Epub 2020 Apr 15. PMID:
32296931
Article Published Date
: Apr 14, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
,
Hesperidin
Diseases
:
Metabolic Syndrome X
Pharmacological Actions
:
Hypolipidemic
,
Insulin Sensitizers
Additional Keywords
:
Natural Substance Synergy
[+]
Consumption of baked nuts or seeds reduces dental plaque acidogenicity after sucrose challenge.
May 31, 2016
Click here to read the entire abstract
Pubmed Data
: Am J Dent. 2016 Jun ;29(3):145-8. PMID:
27505990
Article Published Date
: May 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Nuts
,
Sunflower Seeds
,
Watermelon
Diseases
:
Dental Plaque
Additional Keywords
:
Risk Reduction
Problem Substances
:
Sucrose
[+]
Consumption of flaxseed, a rich source of lignans, is associated with reduced breast cancer risk.
Jan 24, 2013
Click here to read the entire abstract
Pubmed Data
: Cancer Causes Control. 2013 Jan 25. Epub 2013 Jan 25. PMID:
23354422
Article Published Date
: Jan 24, 2013
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Breast Cancer: Prevention
Pharmacological Actions
:
Chemopreventive
[+]
Consumption of Nigella sativa can reduce the inflammatory biomarkers in patients with NAFLD.
May 31, 2019
Click here to read the entire abstract
Pubmed Data
: Complement Ther Med. 2019 Jun ;44:204-209. Epub 2019 Apr 22. PMID:
31126557
Article Published Date
: May 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Consumption of sunflower extract has a beneficial effect on body weight, fat mass, and lipid profile.
May 14, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 May 15 ;11(5). Epub 2019 May 15. PMID:
31096648
Article Published Date
: May 14, 2019
Study Type
: Human Study
Additional Links
Substances
:
Sunflower Seeds
Diseases
:
Obesity
Pharmacological Actions
:
Anticholesteremic Agents
,
Hypolipidemic
Additional Keywords
:
Anti-Obesity Agents
[+]
Cuminum cyminum supplementation can improve some antioxidative indices, while decreasing malondialdehyde in patients with metabolic syndrome.
Mar 31, 2019
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2019 Apr ;33(4):1182-1190. Epub 2019 Feb 14. PMID:
30762267
Article Published Date
: Mar 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Cumin
Diseases
:
C-Reactive Protein
,
Inflammation
,
Metabolic Syndrome X
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Daily intake of N. sativa oil for two months improves abnormal semen quality in infertile men without any adverse effects.
May 14, 2014
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2014 May 15 ;21(6):901-5. Epub 2014 Mar 25. PMID:
24680621
Article Published Date
: May 14, 2014
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Infertility: Male
,
Sperm Quality: Low
Pharmacological Actions
:
Fertility Agents: Male
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Dietary addition of 25 g flaxseed per day results in significantly increased levels of IL-1Ra, an endogenous inhibitor of the proinflammatory IL-1α and IL-1β.
Aug 27, 2012
Click here to read the entire abstract
Pubmed Data
: J Clin Endocrinol Metab. 2012 Aug 28. Epub 2012 Aug 28. PMID:
22930784
Article Published Date
: Aug 27, 2012
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Breast Cancer
Pharmacological Actions
:
Interleukin 1 receptor antagonist (IL-1Ra) up-regulation
[+]
Dietary flaxseed lignan improves lower urinary tract symptoms in benign prostatic hyperplasia subjects as well as drug therapy.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Ren Nutr. 2007 Jan;17(1):23-9. PMID:
18358071
Article Published Date
: Jan 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Prostatic Hyperplasia: Benign
Additional Keywords
:
Natural Substances Versus Drugs
,
Secoisolariciresinol Diglucoside
[+]
Dietary flaxseed may reduce tumor growth in patients with breast cancer.
May 15, 2005
Click here to read the entire abstract
Pubmed Data
: Clin Cancer Res. 2005 May 15;11(10):3828-35. PMID:
15897583
Article Published Date
: May 15, 2005
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Breast Cancer
[+]
Dietary supplementation with flaxseed oil lowers blood pressure in dyslipidaemic patients.
Oct 01, 2007
Click here to read the entire abstract
Pubmed Data
: Eur J Clin Nutr. 2007 Oct;61(10):1201-6. Epub 2007 Jan 31. PMID:
17268413
Article Published Date
: Oct 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
ALA (Alpha-Linolenic Acid)
,
Flaxseed
Diseases
:
Cardiovascular Diseases
,
Dyslipidemias
Pharmacological Actions
:
Hypotensive
[+]
Dosin eradicated H. pylori in about 57% of infected patients.
Oct 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Iran Red Crescent Med J. 2016 Nov ;18(11):e23771. Epub 2016 Jun 21. PMID:
28191328
Article Published Date
: Oct 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Honey
,
Nigella sativa (aka Black Seed)
Diseases
:
Helicobacter Pylori Infection
Pharmacological Actions
:
Anti-Bacterial Agents
[+]
Effect of Nigella sativa oil extracts on inflammatory and oxidative stress markers in Behcet's disease.
Feb 29, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Avicenna J Phytomed. 2020 Mar-Apr;10(2):181-189. PMID:
32257890
Article Published Date
: Feb 29, 2020
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Behcet Disease
Pharmacological Actions
:
Antioxidants
,
Malonaldehyde (MDA) Down-Regulation
[+]
Effectiveness of topical Nigella sativa for vitiligo treatment.
Apr 24, 2019
Click here to read the entire abstract
Pubmed Data
: Dermatol Ther. 2019 Apr 25:e12949. Epub 2019 Apr 25. PMID:
31025474
Article Published Date
: Apr 24, 2019
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Vitiligo
[+]
Flaxseed and borage oil supplementation increases skin hydration in women.
Feb 01, 2009
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2009 Feb;101(3):440-5. Epub 2008 Sep 2. PMID:
18761778
Article Published Date
: Feb 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Borage Oil
,
Flaxseed
,
Omega-3 Fatty Acids
Diseases
:
Dry Skin
[+]
Flaxseed and V. agnus are effective in short-term period in decreasing cyclical mastalgia.
Jan 31, 2016
Click here to read the entire abstract
Pubmed Data
: Complement Ther Med. 2016 Feb ;24:90-5. Epub 2015 Dec 29. PMID:
26860808
Article Published Date
: Jan 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
,
Vitex Agnus
Diseases
:
Mastalgia
Additional Keywords
:
Plant Extracts
[+]
Flaxseed cookies used as a snack may be a useful tool for decreasing constipation symptoms, weight, glycemic and lipid levels in T2D patients.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Metab (Lond). 2018 ;15:36. Epub 2018 May 9. PMID:
29760761
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Constipation
,
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Hypoglycemic Agents
,
Hypolipidemic
,
Laxative
[+]
Flaxseed dietary fiber supplements suppress appetite and food intake.
Jan 05, 2012
Click here to read the entire abstract
Pubmed Data
: Appetite. 2012 Jan 5. Epub 2012 Jan 5. PMID:
22245724
Article Published Date
: Jan 05, 2012
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Appetite Disorders
,
Weight Probems: Appetite
[+]
Flaxseed fiber suppresses postprandial lipemia and appetite in healthy young men.
Feb 01, 2013
Click here to read the entire abstract
Pubmed Data
: Nutr Metab Cardiovasc Dis. 2013 Feb ;23(2):136-43. Epub 2011 Jul 29. PMID:
21802266
Article Published Date
: Feb 01, 2013
Study Type
: Human Study
Additional Links
Substances
:
Fiber
,
Flaxseed
Diseases
:
Hyperlipidemia
Pharmacological Actions
:
Antilipemic Agents
,
Appetite Suppresant
Problem Substances
:
Insulin
[+]
Flaxseed lignan has therapeutic value in the treatment of metabolic syndrome in men.
Apr 01, 2009
Click here to read the entire abstract
Pubmed Data
: Appl Physiol Nutr Metab. 2009 Apr;34(2):89-98. PMID:
19370038
Article Published Date
: Apr 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Metabolic Syndrome X
[+]
Flaxseed may reduce circulating total and LDL-cholesterol levels.
Aug 01, 2009
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2009 Aug;90(2):288-97. Epub 2009 Jun 10. PMID:
19515737
Article Published Date
: Aug 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
,
Lignans
Diseases
:
Cholesterol: LDL/HDL ratio
,
High Cholesterol
Pharmacological Actions
:
Anticholesteremic Agents
[+]
Flaxseed meal and flaxseed extract is effective in reducing menopausal symptoms without increasing blood levels of follicle stimulating hormone and estradiol, as well as in the endometrial thickness, and vaginal epithelial maturation value.
Aug 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2012 Sep ;15(9):840-5. PMID:
22925074
Article Published Date
: Aug 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
,
Secoisolariciresinol diglucoside (SDG)
Diseases
:
Hot Flash
,
Menopausal Syndrome
[+]
Flaxseed oil could be effective in the management of mild and moderate carpal tunnel syndrome, especially in improving the severity of symptoms and functional status
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Daru. 2014 ;22:43. Epub 2014 May 21. PMID:
24887185
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Carpal Tunnel Syndrome
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Phytotherapy
[+]
Flaxseed oil diminishes skin sensitivity and improves skin barrier function and condition.
Nov 18, 2010
Click here to read the entire abstract
Pubmed Data
: Skin Pharmacol Physiol. 2010 Nov 18;24(2):67-74. Epub 2010 Nov 18. PMID:
21088453
Article Published Date
: Nov 18, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Aging Skin
,
Dry Skin
,
Skin Diseases
[+]
Flaxseed oil in the context of a weight loss program ameliorates fatty liver grade in patients with non-alcoholic fatty liver disease.
Jan 28, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Nutr. 2020 Jan 29:1-24. Epub 2020 Jan 29. PMID:
31992372
Article Published Date
: Jan 28, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
Flaxseed oil may be considered a promising agent with cardioprotective properties.
May 04, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Genes Nutr. 2020 May 5 ;15(1):9. Epub 2020 May 5. PMID:
32370762
Article Published Date
: May 04, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Coronary Artery Disease
Pharmacological Actions
:
Cardioprotective
Additional Keywords
:
Endocannabinoid System
[+]
Flaxseed oil omega-3 supplementation for 12 weeks in women with PCOS had beneficial effects.
Mar 31, 2018
Click here to read the entire abstract
Pubmed Data
: Exp Clin Endocrinol Diabetes. 2018 Apr ;126(4):222-228. Epub 2017 Nov 8. PMID:
29117618
Article Published Date
: Mar 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Inflammation
,
Polycystic Ovary Syndrome
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hypolipidemic
[+]
Flaxseed supplementation and a low-fat diet reduces proliferation of benign prostatic epithelium and PSA.
May 01, 2004
Click here to read the entire abstract
Pubmed Data
: Urology. 2004 May;63(5):900-4. PMID:
15134976
Article Published Date
: May 01, 2004
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Prostate: PSA Doubling
,
Prostatic Hyperplasia: Benign
[+]
Flaxseed supplementation appears to be renoprotective in lupus nephritis.
Apr 01, 2001
Click here to read the entire abstract
Pubmed Data
: J Am Coll Nutr. 2001 Apr;20(2 Suppl):143-8. PMID:
11349937
Article Published Date
: Apr 01, 2001
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Lupus Nephritis
[+]
Flaxseed supplementation may help to control cholesterol.
Apr 17, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2020 Apr 18 ;12(4). Epub 2020 Apr 18. PMID:
32325781
Article Published Date
: Apr 17, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Hyperlipidemia
Pharmacological Actions
:
Hypolipidemic
[+]
Flaxseed supplementation plus lifestyle modification is more effective than lifestyle modification alone for NAFLD management.
May 31, 2016
Click here to read the entire abstract
Pubmed Data
: Int J Food Sci Nutr. 2016 Jun ;67(4):461-9. Epub 2016 Mar 17. PMID:
26983396
Article Published Date
: May 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Insulin Resistance
,
Liver Fibrosis
,
Liver Steatosis
,
Nonalcoholic fatty liver disease (NAFLD)
Therapeutic Actions
:
Integrative Medicine
,
Lifestyle Changes: Positive
Pharmacological Actions
:
Anti-Fibrotic
,
Enzyme Inhibitors
,
Hepatoprotective
Additional Keywords
:
Significant Treatment Outcome
[+]
Flaxseed supplementation reduces prostate cancer proliferation rates in men presurgery.
Dec 01, 2008
Click here to read the entire abstract
Pubmed Data
: Cancer Epidemiol Biomarkers Prev. 2008 Dec;17(12):3577-87. PMID:
19064574
Article Published Date
: Dec 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Prostate Cancer
[+]
Flaxseed therapy has a significant effect in managing hot flash in women not taking estrogen therapy.
Jun 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Soc Integr Oncol. 2007 Summer;5(3):106-12. PMID:
17761129
Article Published Date
: Jun 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Estrogen Deficiency
,
Hot Flash
[+]
Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer.
Mar 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Med Food. 2013 Apr ;16(4):357-60. PMID:
23566060
Article Published Date
: Mar 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Enterolactone
,
Flaxseed
,
Lignans
Diseases
:
Prostate Cancer
,
Prostate Cancer: Prevention
Pharmacological Actions
:
Antiproliferative
,
Chemopreventive
,
Vascular Endothelial Growth Factor A Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Hemp seed and evening primrose oils with hot-nature diet have beneficial effects in improving the clinical score in multiple sclerosis patients.
Sep 30, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Complement Ther Med. 2013 Oct ;21(5):473-80. Epub 2013 Jul 25. PMID:
24050582
Article Published Date
: Sep 30, 2013
Study Type
: Human Study
Additional Links
Substances
:
Evening Primrose Oil
,
Hemp Seed
Diseases
:
Inflammation
,
Multiple Sclerosis: Relapsing-Remitting
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Immunomodulatory
Additional Keywords
:
Dietary Modification
,
Phytotherapy
,
Plant Extracts
[+]
Herbal product use during the last 2 trimesters of pregnancy and more specifically, use of flax, chamomile, peppermint, or green tea alone or in combination with other HPs did not significantly increase the risk of LBW.
Feb 29, 2012
Click here to read the entire abstract
Pubmed Data
: Altern Ther Health Med. 2012 Mar-Apr;18(2):36-43. PMID:
22516883
Article Published Date
: Feb 29, 2012
Study Type
: Human Study
Additional Links
Substances
:
Chamomile
,
Flaxseed
,
Green Tea
,
Peppermint
Diseases
:
Prenatal Herb Exposure
Additional Keywords
:
Herb Safety
[+]
High dietary intakes of plant lignans and high exposure to enterolignans were associated with reduced risks of ER- and PR-positive postmenopausal breast cancer.
Mar 21, 2007
Click here to read the entire abstract
Pubmed Data
: J Natl Cancer Inst. 2007 Mar 21;99(6):475-86. PMID:
17374837
Article Published Date
: Mar 21, 2007
Study Type
: Human Study
Additional Links
Substances
:
Enterodiol
,
Enterolactone
,
Flaxseed
,
Lignans
,
phytoestrogens
Diseases
:
Breast Cancer
,
Breast Cancer: Prevention
Additional Keywords
:
Risk Reduction
[+]
Honey and celery seeds could be beneficial in bronchial asthma.
May 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2019 Jun ;22(6):543-550. Epub 2019 May 24. PMID:
31135254
Article Published Date
: May 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Celery seed
,
Honey
,
Nigella sativa (aka Black Seed)
Diseases
:
Asthma: Bronchial
Pharmacological Actions
:
Anti-Asthmatic Agents
[+]
It is recommended that clinicians and wound care nurses use aloe vera gel instead of Nigella sativa oil gel for the topical treatment of diabetic ulcers.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: J Evid Based Integr Med. 2018 Jan-Dec;23:2515690X18772804. PMID:
29717629
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Aloe Vera
,
Nigella sativa (aka Black Seed)
Diseases
:
Diabetic Ulcer
,
Wound Healing
[+]
Lignan content of the flaxseed influences its biological effects in healthy men and women.
May 31, 2013
Click here to read the entire abstract
Pubmed Data
: J Am Coll Nutr. 2013 Jun ;32(3):194-9. PMID:
23885993
Article Published Date
: May 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
,
Lignans
Diseases
:
Cholesterol: Oxidation
,
High Cholesterol
[+]
Long-term flaxseed lignan-enriched complex supplementation in older adults has an ability to favourably modulate systolic blood pressure.
Oct 31, 2017
Click here to read the entire abstract
Pubmed Data
: J Am Coll Nutr. 2017 Nov-Dec;36(8):646-653. Epub 2017 Sep 18. PMID:
28922068
Article Published Date
: Oct 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
,
Lignans
Diseases
:
Cardiovascular Diseases
,
Hypertension
,
Inflammation
Pharmacological Actions
:
Antihypertensive Agents
Additional Keywords
:
Risk Reduction
[+]
Milled flaxseed lowers total and LDL cholesterol in patients with peripheral artery disease.
Mar 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2015 Apr ;145(4):749-57. Epub 2015 Feb 18. PMID:
25694068
Article Published Date
: Mar 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Cholesterol: High
,
Peripheral Arterial Disease
Pharmacological Actions
:
Anticholesteremic Agents
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
N sativa supplementation with inhaled maintenance therapy improves some measures of pulmonary function and inflammation in partly controlled asthma.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Saudi Med. 2017 Jan-Feb;37(1):64-71. PMID:
28151459
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Asthma
Pharmacological Actions
:
Bronchodilator Agents
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
N. sativa administration in patients with HCV was tolerable, safe, decreased viral load, and improved oxidative stress, clinical condition and glycemic control in diabetic patients.
Apr 27, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Article Published Date
: Apr 27, 2013
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Hepatitis C
[+]
N. sativa could be a promising, safe, and easily available analgesic supplement in women suffering from primary dysmenorrhea.
Aug 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oman Med J. 2020 Sep ;35(5):e167. Epub 2020 Sep 9. PMID:
32953142
Article Published Date
: Aug 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Dysmenorrhea
Pharmacological Actions
:
Analgesics
[+]
N. sativa extract significantly decreases the severity of acute radiation dermatitis and delays the onset of moist desquamation in breast cancer patients.
Nov 30, 2019
Click here to read the entire abstract
Pubmed Data
: Complement Ther Med. 2019 Dec ;47:102205. Epub 2019 Oct 3. PMID:
31780017
Article Published Date
: Nov 30, 2019
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Breast Cancer
,
Chemotherapy and Radiation Toxicity
,
Dermatitis
Pharmacological Actions
:
Radioprotective
[+]
N. sativa hydrogel had significant effects on improving the symptoms of acne vulgaris with acceptable tolerability.
Jun 16, 2020
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2020 Jun 17. Epub 2020 Jun 17. PMID:
32548864
Article Published Date
: Jun 16, 2020
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Acne
Pharmacological Actions
:
Anti-Bacterial Agents
[+]
N. sativa is demonstrated to have significant positive effects on disappearance or reduction of size of kidney stones.
Mar 13, 2019
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2019 Mar 14. Epub 2019 Mar 14. PMID:
30873671
Article Published Date
: Mar 13, 2019
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Kidney Stones
[+]
N. sativa oil supplementation along with alpha-keto analogue is efficacious and safe in delaying the progression of disease patients with CKD Stages 3 and 4.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Saudi J Kidney Dis Transpl. 2020 Jan-Feb;31(1):21-31. PMID:
32129194
Article Published Date
: Dec 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Chronic Kidney Disease (CKD)
Pharmacological Actions
:
Renoprotective
Additional Keywords
:
Risk Reduction
[+]
N. sativa oil was found to be effective as an add-on therapy in patients of insulin resistance syndrome.
Dec 31, 2007
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Diabetes Dev Ctries. 2008 Jan ;28(1):11-4. PMID:
19902033
Article Published Date
: Dec 31, 2007
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Insulin Resistance
Pharmacological Actions
:
Anticholesteremic Agents
,
Hypoglycemic Agents
[+]
N. sativa seed oil has clinical effectiveness comparable to topical diclofenac in the treatment of cyclic mastalgia.
Nov 18, 2015
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2015 Nov 19. Epub 2015 Nov 19. PMID:
26584456
Article Published Date
: Nov 18, 2015
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Mastalgia
Pharmacological Actions
:
Analgesics
Additional Keywords
:
Natural Substances Versus Drugs
Problem Substances
:
Diclofenac
[+]
N. sativa seed supplementation during specific immunotherapy of allergic rhinitis may be considered a potential adjuvant therapy.
Dec 31, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Med Princ Pract. 2010 ;19(3):206-11. Epub 2010 Mar 29. PMID:
20357504
Article Published Date
: Dec 31, 2009
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Allergic Rhinitis
Pharmacological Actions
:
Immunomodulatory
Additional Keywords
:
Phytotherapy
,
Significant Treatment Outcome
[+]
N. sativa seeds is beneficial in relieving the symptoms of knee osteoarthritis.
Apr 04, 2017
Click here to read the entire abstract
Pubmed Data
: Int J Rheum Dis. 2017 Apr 5. Epub 2017 Apr 5. PMID:
28378356
Article Published Date
: Apr 04, 2017
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Osteoarthritis
Additional Keywords
:
Significant Treatment Outcome
[+]
Nigella sativa (black cumin) has potent antiasthmatic properties.
Feb 08, 2010
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2010 Feb 8. Epub 2010 Feb 8. PMID:
20149611
Article Published Date
: Feb 08, 2010
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Asthma
Pharmacological Actions
:
Bronchodilator Agents
[+]
Nigella sativa could improve inflammation and reduce oxidative stress in patients with rheumatoid arthritis.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Avicenna J Phytomed. 2016 Jan-Feb;6(1):34-43. PMID:
27247920
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Nigella sativa enhances memory, attention and cognition in healthy human volunteers.
Jul 29, 2013
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2013 Jul 30 ;148(3):780-6. Epub 2013 May 21. PMID:
23707331
Article Published Date
: Jul 29, 2013
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Cognitive Decline/Dysfunction
,
Memory Disorders
[+]
Nigella sativa oil concurrent with a low-calorie diet decreased weight and increased SOD levels in obese women.
Jul 13, 2015
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2015 Jul 14. Epub 2015 Jul 14. PMID:
26179113
Article Published Date
: Jul 13, 2015
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Obesity
,
Oxidative Stress
Therapeutic Actions
:
Dietary Modification: Low Calorie Diet
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
Nigella sativa oil mouth rinse improves chemotherapy-induced oral mucositis in patients with acute myeloid leukemia.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2019 ;2019:3619357. Epub 2019 Oct 30. PMID:
31781612
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Acute Myeloid Leukemia
,
Radiation Induced Illness: Mucositis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Radioprotective
[+]
Nigella sativa oil supplement has cardiovascular protective effects in patients with T2DM.
Jun 07, 2020
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2020 Jun 8. Epub 2020 Jun 8. PMID:
32510754
Article Published Date
: Jun 07, 2020
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
C-Reactive Protein
,
Cardiovascular Diseases
,
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticholesteremic Agents
,
Antioxidants
,
Cardioprotective
,
Hypoglycemic Agents
,
Hypolipidemic
[+]
Nigella sativa oil supplementation combined with a calorie-restricted diet may modulate systemic inflammatory biomarkers in obese women.
Aug 31, 2016
Click here to read the entire abstract
Pubmed Data
: J Clin Lipidol. 2016 Sep-Oct;10(5):1203-11. Epub 2015 Dec 7. PMID:
27678438
Article Published Date
: Aug 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Inflammation
,
Obesity
Therapeutic Actions
:
Dietary Modification: Low Calorie Diet
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Oils
[+]
Nigella sativa oil supplementation had a protective effect in diabetic nephropathy.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Saudi J Kidney Dis Transpl. 2017 Jan-Feb;28(1):9-14. PMID:
28098097
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Diabetic Nephropathy
Pharmacological Actions
:
Hypoglycemic Agents
[+]
Nigella sativa seed oil supplements may decrease the liver enzymes and lipid profiles in the patients with NAFLD.
Nov 30, 2019
Click here to read the entire abstract
Pubmed Data
: J Diabetes Metab Disord. 2019 Dec ;18(2):453-459. Epub 2019 Sep 11. PMID:
31890671
Article Published Date
: Nov 30, 2019
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
,
Thymoquinone
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Nigella sativa seeds can be considered as a therapeutic agent in management of Hashimoto-related metabolic abnormalities.
May 31, 2020
Click here to read the entire abstract
Pubmed Data
: Clin Nutr ESPEN. 2020 Jun ;37:207-212. Epub 2020 Mar 10. PMID:
32359745
Article Published Date
: May 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Endothelial Dysfunction
,
Hashimoto's thyroiditis
Pharmacological Actions
:
Antioxidants
[+]
Nigella sativa seeds powder may be of interest in lowering lipid concentrations in hyperlipidemic subjects.
Mar 14, 2019
Click here to read the entire abstract
Pubmed Data
: Br J Clin Pharmacol. 2019 Mar 15. Epub 2019 Mar 15. PMID:
30875097
Article Published Date
: Mar 14, 2019
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Hyperlipidemia
Pharmacological Actions
:
Hypolipidemic
[+]
Nigella sativa seeds showed a decrease in incidence of febrile neutropenia in children with brain tumors undergoing chemotherapy.
Mar 26, 2017
Click here to read the entire abstract
Pubmed Data
: Childs Nerv Syst. 2017 Mar 27. Epub 2017 Mar 27. PMID:
28349493
Article Published Date
: Mar 26, 2017
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Chemotherapy and Radiation Toxicity
Pharmacological Actions
:
Chemoprotective Agents
Additional Keywords
:
Risk Reduction
,
Significant Treatment Outcome
[+]
Nigella sativa Supplementation Improves Asthma Control and Biomarkers: A Randomized, Double-Blind, Placebo-Controlled Trial.
Jan 16, 2017
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2017 Jan 17. Epub 2017 Jan 17. PMID:
28093815
Article Published Date
: Jan 16, 2017
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Asthma
,
Eosinophilia
Pharmacological Actions
:
anti-inflammatory
Additional Keywords
:
anti-inflammatory
,
Asthma
,
Black Seed
,
Eosinophilia
,
Nigella sativa oil (NSO)
[+]
Omega-3 dietary supplementation may have a therapeutic effect in blepharitis and meibomian gland dysfunction.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Trans Am Ophthalmol Soc. 2008;106:336-56. PMID:
19277245
Article Published Date
: Jan 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
,
Olive
,
Omega-3 Fatty Acids
Diseases
:
Blepharitis
,
Meibomian gland dysfunction
[+]
Omega-3 fatty acids supplementation for 6 weeks to women with gestational diabetes mellitus had beneficial effects.
Jan 05, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Nutr. 2020 Jan 6:1-26. Epub 2020 Jan 6. PMID:
31902378
Article Published Date
: Jan 05, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
,
Omega-3 Fatty Acids
Diseases
:
Gestational Diabetes
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hypoglycemic Agents
,
Hypolipidemic
Additional Keywords
:
Gene Expression Regulation
[+]
Potent antihypertensive action of dietary flaxseed in hypertensive patients.
Nov 30, 2013
Click here to read the entire abstract
Pubmed Data
: Hypertension. 2013 Dec ;62(6):1081-9. Epub 2013 Oct 14. PMID:
24126178
Article Published Date
: Nov 30, 2013
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
Additional Keywords
:
Phytotherapy
[+]
Powdered Nigella sativa has potent beneficial effects in improving thyroid status and anthropometric variables.
Nov 15, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2016 Nov 16 ;16(1):471. Epub 2016 Nov 16. PMID:
27852303
Article Published Date
: Nov 15, 2016
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Hashimoto's thyroiditis
Pharmacological Actions
:
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Plant Extracts
[+]
Protective Effects of Nigella sativa on Metabolic Syndrome in Menopausal Women
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Adv Pharm Bull. 2014 ;4(1):29-33. Epub 2013 Dec 23. PMID:
24409406
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Cholesterol: High
,
Cholesterol: LDL/HDL ratio
,
HDL: Low
,
Metabolic Syndrome X
[+]
Pumpkin seed consumption contributes to alleviating iron-deficiency associated anemia.
Jul 01, 1995
Click here to read the entire abstract
Pubmed Data
: AIDS Asia. 1995 Jul-Aug;2(4):6-7. PMID:
18198398
Article Published Date
: Jul 01, 1995
Study Type
: Human Study
Additional Links
Substances
:
Pumpkin Seed Oil/Meal
Diseases
:
Anemia: Iron Deficiency
[+]
Pumpkin seed oil (prostafit) is effective and a safe alternative treatment in benign prostatic hyperplasia.
May 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Pak Med Assoc. 2014 Jun ;64(6):683-5. PMID:
25252490
Article Published Date
: May 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Pumpkin Seed Oil/Meal
Diseases
:
Prostatic Hyperplasia: Benign
Additional Keywords
:
Phytotherapy
,
Plant Oils
[+]
Pumpkin seed oil extracted from C. maxima has the potential for prevention or treatment of urinary disorders.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Tradit Complement Med. 2014 Jan ;4(1):72-4. PMID:
24872936
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Pumpkin Seed Oil/Meal
Diseases
:
Overactive Bladder
[+]
Pumpkin seed oil has beneficial properties in postmenopausal women.
May 05, 2011
Click here to read the entire abstract
Pubmed Data
: Climacteric. 2011 May 5. Epub 2011 May 5. PMID:
21545273
Article Published Date
: May 05, 2011
Study Type
: Human Study
Additional Links
Substances
:
Pumpkin Seed Oil/Meal
Diseases
:
HDL: Low
,
Hot Flash
,
Postmenopausal Disorders
[+]
Pumpkin seeds reduce calcium-oxalate crystal occurence in the urine of children.
Jan 01, 1987
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 1987 Jan;45(1):115-21. PMID:
3799495
Article Published Date
: Jan 01, 1987
Study Type
: Human Study
Additional Links
Substances
:
Pumpkin Seed Oil/Meal
Diseases
:
Bladder Stones
,
Kidney Failure: Acute
[+]
Sesame consumption may reduce muscle damage and oxidative stress while improving the aerobic capacity in soccer players.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Physiol. 2017 ;8:196. Epub 2017 Mar 31. PMID:
28408889
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Sesame Seeds
Diseases
:
Athletic Performance
,
Muscle Damage: Exercise-Induced
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
Sesame lignans with vitamin E supplementation could safely alleviate daily fatigue and oxidative stress.
Mar 24, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Glob J Health Sci. 2015 Mar 25 ;7(6):1-10. Epub 2015 Mar 25. PMID:
26153159
Article Published Date
: Mar 24, 2015
Study Type
: Human Study
Additional Links
Substances
:
Lignans
,
Sesame Seeds
Diseases
:
Chronic Fatigue Syndrome
,
Fatigue
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
Sesame seed is a natural and safe substance that may have beneficial effects in patients with knee osteoarthritis.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Acta Med Iran. 2015 ;53(4):207-13. PMID:
25871017
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Sesame Seeds
Diseases
:
C-Reactive Protein
,
Inflammation
,
Osteoarthritis: Knee
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
[+]
Sesame seed paste reduces cardiovascular disease risk factors in type 2 diabetics.
Oct 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Article Published Date
: Oct 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Sesame Seeds
Diseases
:
Atherosclerosis
,
Cardiovascular Diseases
,
Cholesterol: LDL/HDL ratio
,
Diabetes: Cardiovascular Illness
,
Triglycerides: Elevated
Pharmacological Actions
:
Cardioprotective
[+]
Sesame seed supplementation compares favorably to drug therapy on clinical signs and symptoms in patients with knee osteoarthritis.
Sep 30, 2013
Click here to read the entire abstract
Article Published Date
: Sep 30, 2013
Study Type
: Human Study
Additional Links
Substances
:
Sesame Seeds
Diseases
:
Osteoarthritis
,
Osteoarthritis: Knee
Pharmacological Actions
:
anti-inflammatory
Additional Keywords
:
Natural Substances Versus Drugs
[+]
Sesamin (a compound found within sesame seeds) and Schisandra extract improves blood fluidity.
Jan 27, 2008
Click here to read the entire abstract
Pubmed Data
: Bioinformation. 2008 Jan 27;2(6):249-52. PMID:
18317575
Article Published Date
: Jan 27, 2008
Study Type
: Human Study
Additional Links
Substances
:
Schisandra
,
Sesame Seeds
Diseases
:
Blood Viscosity: Elevated
,
Hyperviscosity Syndrome
[+]
Sesamin exhibited a protective effect on cardiovascular risk factors in patients with rheumatoid arthritis.
Apr 30, 2016
Click here to read the entire abstract
Pubmed Data
: J Am Coll Nutr. 2016 May-Jun;35(4):300-7. Epub 2015 Jul 7. PMID:
26151734
Article Published Date
: Apr 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Sesame Seeds
Diseases
:
Cardiovascular Diseases
,
Hypertension
,
Oxidative Stress
,
Rheumatoid Arthritis
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Malondialdehyde Down-regulation
[+]
Supplementation of honey and N. sativa can cause significant symptomatic improvement of patients with functional dyspepsia whom received the standard anti-secretory therapy.
Sep 15, 2015
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2015 Sep 16. Epub 2015 Sep 16. PMID:
26386381
Article Published Date
: Sep 15, 2015
Study Type
: Human Study
Additional Links
Substances
:
Honey
,
Nigella sativa (aka Black Seed)
Diseases
:
Dyspepsia
,
Helicobacter Pylori Infection
[+]
Supplementation with flax oil and vitamin C improves the outcome of ADHD.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: Prostaglandins Leukot Essent Fatty Acids. 2006 Jan;74(1):17-21. Epub 2005 Nov 28. PMID:
16314082
Article Published Date
: Jan 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
,
Vitamin C
Diseases
:
Attention Deficit Disorder with Hyperactivity
[+]
Taking cumin cyminum L. for eight weeks among overweight subjects had the same effects of orlistat120 on weight and BMI but with beneficial effects on insulin metabolism.
Mar 02, 2015
Click here to read the entire abstract
Pubmed Data
: Ann Nutr Metab. 2015 Mar 3 ;66(2-3):117-124. Epub 2015 Mar 3. PMID:
25766448
Article Published Date
: Mar 02, 2015
Study Type
: Human Study
Additional Links
Substances
:
Cumin
Diseases
:
Obesity
,
Oxidative Stress
Therapeutic Actions
:
Weight Reduction
Pharmacological Actions
:
Antioxidants
,
Insulin Down-Regulation
Additional Keywords
:
Natural Substances Versus Drugs
,
Superiority of Natural Substances versus Drugs
[+]
The beneficial effects of flaxseed supplementation on metabolic status in women with polycystic ovary syndrome.
Jan 23, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr J. 2020 Jan 24 ;19(1):8. Epub 2020 Jan 24. PMID:
31980022
Article Published Date
: Jan 23, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Polycystic Ovary Syndrome
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Insulin Sensitizers
,
Interleukin-6 Downregulation
[+]
The beneficial health effects of Nigella sativa on Helicobacter pylori eradication, dyspepsia symptoms, and quality of life in infected patients.
Jan 08, 2020
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2020 Jan 9. Epub 2020 Jan 9. PMID:
31916648
Article Published Date
: Jan 08, 2020
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Dyspepsia
,
Helicobacter Pylori Infection
Pharmacological Actions
:
Anti-Bacterial Agents
[+]
The combination of black seeds and turmeric can be recommended with lifestyle modification as a starting point for patients with MetS to halt its future complications and progression.
Mar 31, 2015
Click here to read the entire abstract
Pubmed Data
: Complement Ther Med. 2015 Apr ;23(2):165-74. Epub 2015 Jan 14. PMID:
25847554
Article Published Date
: Mar 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
,
Turmeric
Diseases
:
Metabolic Diseases
Pharmacological Actions
:
Antihypertensive Agents
,
Hypoglycemic Agents
,
Hypolipidemic
Additional Keywords
:
Natural Substance Synergy
,
Significant Treatment Outcome
[+]
The daily use of black cumin seeds for 2 months may have a blood pressure-lowering effect in patients with mild hypertension.
Apr 01, 2006
Click here to read the entire abstract
Pubmed Data
: Braz J Med Biol Res. 2006 Apr;39(4):421-9. Epub 2006 Apr 3. PMID:
18705755
Article Published Date
: Apr 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
,
Hypotensive
Additional Keywords
:
Plant Extracts
[+]
The effect of flaxseed dose on circulating concentrations of alpha-linolenic acid and secoisolariciresinol diglucoside derived enterolignans in young, healthy adults.
Mar 25, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2015 Mar 26. Epub 2015 Mar 26. PMID:
25808116
Article Published Date
: Mar 25, 2015
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
,
Flaxseed Oil
Diseases
:
Omega-3 Fatty Acid Deficiency
Additional Keywords
:
ALA To EPA Conversion
[+]
The fixed oil extracted from Nigella sativa seeds has an in vitro antisickling activity.
Feb 28, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Singapore Med J. 2010 Mar ;51(3):230-4. PMID:
20428745
Article Published Date
: Feb 28, 2010
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Sickle Cell Anemia
Additional Keywords
:
Plant Oils
[+]
The use of N. sativa nasal spray has symptom reliever effect with no adverse effects in patients.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Allergy Rhinol (Providence). 2018 Jan-Dec;9:2152656718800059. Epub 2018 Oct 4. PMID:
30370173
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Rhinosinusitis
Additional Keywords
:
Significant Treatment Outcome
[+]
The water extract of black cumin seed has significant anti-epileptic activity in children.
Dec 01, 2007
Click here to read the entire abstract
Pubmed Data
: Med Sci Monit. 2007 Dec;13(12):CR555-9. PMID:
18049435
Article Published Date
: Dec 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Epilepsy: Childhood
[+]
These pilot data suggest that a flaxseed-supplemented, fat-restricted diet may affect prostate cancer biology and associated biomarkers.
Jun 30, 2001
Click here to read the entire abstract
Pubmed Data
: Urology. 2001 Jul ;58(1):47-52. PMID:
11445478
Article Published Date
: Jun 30, 2001
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Prostate Cancer
,
Testosterone: Too High
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
This study gives strength to the potential relevance of Nigella sativa in clinical management of rheumatoid arthritis.
Apr 30, 2016
Click here to read the entire abstract
Pubmed Data
: Immunol Invest. 2016 May ;45(4):271-83. Epub 2016 Apr 21. PMID:
27100726
Article Published Date
: Apr 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
C-Reactive Protein
,
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Immunomodulatory
[+]
This study indicates that daily consumption of 6 g/d of flaxseed oil may reduce bone resorption in hemodialysis patients.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Iran J Kidney Dis. 2018 07 ;12(4):215-222. PMID:
30087216
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Bone Diseases
,
Hemodialysis
Pharmacological Actions
:
Osteoprotective
[+]
Topical application of N. sativa oil is effective in the prevention of chemotherapy-induced phlebitis.
Aug 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomedicine (Taipei). 2019 Sep ;9(3):20. Epub 2019 Aug 27. PMID:
31453801
Article Published Date
: Aug 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Chemotherapy-Induced Phlebitis (CIP)
Pharmacological Actions
:
Chemoprotective Agents
[+]
Topical application of Nigella sativa oil was effective in reducing pain in patients with knee osteoarthritis.
Oct 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Electron Physician. 2016 Nov ;8(11):3193-3197. Epub 2016 Nov 25. PMID:
28344755
Article Published Date
: Oct 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Osteoarthritis: Knee
Pharmacological Actions
:
Analgesics
[+]
Tryptophan-rich gourd seeds are a potential anxiolytic to those suffering from social phobia.
Sep 01, 2007
Click here to read the entire abstract
Pubmed Data
: Can J Physiol Pharmacol. 2007 Sep;85(9):928-32. PMID:
18066139
Article Published Date
: Sep 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Gourd
,
Pumpkin Seed Oil/Meal
,
Tryptophan
Diseases
:
Anti-Social Behavior
,
Anxiety Disorders
,
Phobia: Social
Pharmacological Actions
:
Anxiolytic
[+]
Tryptophan-rich gourd seeds significantly improve subjective and objective measurements of insomnia.
Apr 01, 2005
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2005 Apr;8(2):121-7. PMID:
16053244
Article Published Date
: Apr 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Gourd
,
Pumpkin Seed Oil/Meal
,
Tryptophan
Diseases
:
Insomnia
[+]
Walnuts and flax may have cardioprotective properties in subjects with elevated cholesterol.
Nov 30, 2010
Click here to read the entire abstract
Pubmed Data
: J Am Coll Nutr. 2010 Dec ;29(6):595-603. PMID:
21677123
Article Published Date
: Nov 30, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
,
Walnut
Diseases
:
Cardiovascular Diseases
,
High Cholesterol
,
Hypertension
Pharmacological Actions
:
Cardioprotective
[+]
A Nigella sativa extract showed a 88.3% inhibition of proliferation of SiHa human cervical cancer cells and increased the expression of caspase-3, -8 and -9 several-fold
Jan 31, 2013
Click here to read the entire abstract
Pubmed Data
: Nat Prod Commun. 2013 Feb ;8(2):213-6. PMID:
23513732
Article Published Date
: Jan 31, 2013
Study Type
: Human In Vitro
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Cervical Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Caspase-3 Activation
,
Caspase-8 activation
,
Caspase-9 Activation
,
Tumor Suppressor Protein p53 Upregulation
Additional Keywords
:
Plant Extracts
[+]
Black seed, sweet orange, and Anthemis hyalina extracts all exhibit antiviral activity against coronavirus.
Mar 01, 2014
Click here to read the entire abstract
Pubmed Data
: Mol Biol Rep. 2014 Mar ;41(3):1703-11. Epub 2014 Jan 12. PMID:
24413991
Article Published Date
: Mar 01, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
,
Sweet Orange
Diseases
:
Coronavirus Disease
,
Coronavirus Infection
,
Severe Acute Respiratory Syndrome
Pharmacological Actions
:
Antiviral Agents
Additional Keywords
:
Plant Extracts
[+]
N. sativa oil could be used against multi-drug resistant S. aureus in the treatment of diabetic wounds.
Oct 31, 2015
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2015 Nov ;28(6):1985-90. PMID:
26639493
Article Published Date
: Oct 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Staphylococcus aureus: Methicillin-resistant (MRSA)
Pharmacological Actions
:
Anti-Bacterial Agents
Additional Keywords
:
Dose Response
[+]
Nigella sativa has successfully produced inhibition of growth of MCF cell lines with an equivalent potency as that of the standard cisplatin.
Mar 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmacognosy Res. 2015 Apr-Jun;7(2):193-7. PMID:
25829794
Article Published Date
: Mar 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Breast Cancer
,
Liver Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Natural Substances Versus Drugs
,
Superiority of Natural Substances versus Drugs
[+]
Thymoquinone-rich fractions of Nigella sativa could be an alternative to combat oxidative stress insults in neurodegenerative diseases.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2016 ;2016:2528935. Epub 2015 Dec 28. PMID:
26823946
Article Published Date
: Dec 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
,
Thymoquinone
Diseases
:
Hydrogen Peroxide Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
Additional Keywords
:
Gene Expression Regulation
,
Plant Extracts
[+]
Nigella Sativa Concoction Induced Sustained Seroreversion in HIV Patient.
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
:
PMID: 24311845
Article Published Date
: Dec 31, 2012
Study Type
: Human: Case Report
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
HIV Infections
Pharmacological Actions
:
Antiviral Agents
,
Immunomodulatory
[+]
The effect of flaxseed supplementation on hormonal levels associated with polycystic ovarian syndrome.
Dec 31, 2006
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Curr Top Nutraceutical Res. 2007 ;5(4):177-181. PMID:
19789727
Article Published Date
: Dec 31, 2006
Study Type
: Human: Case Report
Additional Links
Substances
:
Flaxseed
Diseases
:
Polycystic Ovary Syndrome
,
Testosterone: Too High
[+]
Traditional Chinese medicine hemp seed pill could improve chronic constipation of elderly.
May 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Family Med Prim Care. 2019 Jun ;8(6):2150. PMID:
31334198
Article Published Date
: May 31, 2019
Study Type
: Human: Case Report
Additional Links
Substances
:
Hemp Seed
Diseases
:
Constipation
Pharmacological Actions
:
Laxative
[+]
Sesame lignans suppress age-related disorders of the kidney in mice.
Apr 30, 2020
Click here to read the entire abstract
Pubmed Data
: Eur Rev Med Pharmacol Sci. 2020 May ;24(9):5140-5147. PMID:
32432778
Article Published Date
: Apr 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Sesame Seeds
Diseases
:
Kidney Damage
Pharmacological Actions
:
Renoprotective
[+]
"Nigella sativa (black cumin) seed extract alleviates symptoms of allergic diarrhea in mice, involving opioid receptors."
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2012 ;7(6):e39841. Epub 2012 Jun 29. PMID:
22768141
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Diarrhea
,
Food Allergies
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
A combination of black seeds and turmeric at low doses showed enhanced efficacy in preventing metabolic syndrome in fructose fed rats.
Jan 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Cardiovasc Pharmacol. 2015 Feb ;65(2):176-83. PMID:
25384193
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
,
Turmeric
Diseases
:
Dyslipidemias
,
Endothelial Dysfunction
,
Fructose-Induced Toxicity
,
Hyperglycemia
,
Hyperinsulinism
,
Hypertension
,
Metabolic Diseases
Pharmacological Actions
:
Anticholesteremic Agents
,
Antihypertensive Agents
,
Hypoglycemic Agents
,
Hypolipidemic
Additional Keywords
:
Natural Substance Synergy
,
Risk Reduction
[+]
A diet containing flaxseed flour contributed to bone mineral density and femur resistance.
Apr 30, 2018
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2018 May ;49:48-50. Epub 2017 Dec 7. PMID:
29494999
Article Published Date
: Apr 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Pharmacological Actions
:
Osteoprotective
[+]
A flax and pumpkin seed mixture has anti-atherogenic and hepatoprotective effects.
Dec 01, 2008
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2008 Dec;46(12):3714-20. Epub 2008 Oct 1. PMID:
18938206
Article Published Date
: Dec 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
,
Omega-3 Fatty Acids
,
Pumpkin Seed Oil/Meal
Diseases
:
Arteriosclerosis
,
High Cholesterol
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
A hemp seed meal protein hydrolysate contained antioxidant peptides that reduced the rate of lipid peroxidation in spontaneously hypertensive rats.
Nov 30, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2014 Dec ;6(12):5652-66. PMID:
25493943
Article Published Date
: Nov 30, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Cannabis
,
Hemp Seed
Diseases
:
Hypertension
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
[+]
A hemp seed meal protein hydrolysate had strong hypotensive effects in spontaneously hypertensive rats.
Jul 31, 2014
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2014 Aug ;53(5):1237-46. Epub 2013 Nov 29. PMID:
24292743
Article Published Date
: Jul 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Cannabis
,
Hemp Seed
Diseases
:
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
[+]
A hydro-alcoholic extract of nigella sativa reduced the LPS-induced sickness behaviors in rats.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Avicenna J Phytomed. 2016 Jan-Feb;6(1):104-16. PMID:
27247927
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Lipopolysaccharide-Induced Toxicity
Additional Keywords
:
Plant Extracts
[+]
A hydroalcoholic extract of the Nigella sativa decreased oxidative stress in hippocampus of the STZ-induced diabetic rats.
Jun 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Avicenna J Phytomed. 2015 Jul-Aug;5(4):333-40. PMID:
26445713
Article Published Date
: Jun 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Brain: Oxidative Stress
,
Diabetic Complications
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
A liposomal preparation of black seed oil demonstrated significant analgesic activity in mice.
Feb 28, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Saudi Pharm J. 2017 Mar ;25(3):404-412. Epub 2016 Oct 1. PMID:
28344496
Article Published Date
: Feb 28, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Chronic Pain
Pharmacological Actions
:
Analgesics
Additional Keywords
:
Liposomal
[+]
A marine-herbal combination containing prawns, celery seed and st. john's wort has therapeutic value in an animal model of multiple sclerosis.
Aug 01, 2008
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2008 Aug;22(8):1083-6. PMID:
18570265
Article Published Date
: Aug 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Celery seed
,
Penaeus Latisculatus (prawn)
,
St. Johns Wort
Diseases
:
Multiple Sclerosis
[+]
A mixture of flaxseed linusorbs, exerts anti-inflammatory effects.
Jun 03, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomolecules. 2020 Jun 4 ;10(6). Epub 2020 Jun 4. PMID:
32512905
Article Published Date
: Jun 03, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
A plant mixture comprising Nigella sativa, Myrrh, Gum Olibanum (Frankincense), Gum Asafoetida and Aloe lowers blood sugar by inhibiting hepatis gluconeogenesis.
Dec 01, 1991
Click here to read the entire abstract
Pubmed Data
: Diabetes Res. 1991 Dec;18(4):163-8. PMID:
1842751
Article Published Date
: Dec 01, 1991
Study Type
: Animal Study
Additional Links
Substances
:
Aloe Vera
,
Asafoetida
,
Frankincense
,
Myrrh
,
Nigella sativa (aka Black Seed)
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Gluconeogenesis Inhibitor
Additional Keywords
:
Plant Extracts
[+]
A thymoquinone-rich fraction extracted from Nigella sativa effectively improved the plasma and liver antioxidant capacity.
Feb 28, 2010
Click here to read the entire abstract
Pubmed Data
: Free Radic Biol Med. 2010 Mar 1 ;48(5):664-72. Epub 2009 Dec 11. PMID:
20005291
Article Published Date
: Feb 28, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Hypercholesterolemia
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Gene Expression Regulation
[+]
A traditional Indian medical formula containing clarified butter (ghee), flax seed oil, amla (P. emblica fruits), Shorea robusta resin and zinc (Yashada bhasma) stimulates wound healing and tissue regeneration.
Feb 27, 2009
Click here to read the entire abstract
Pubmed Data
: Evid Based Complement Alternat Med. 2009 Feb 27. PMID:
19252191
Article Published Date
: Feb 27, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Amla Fruit
,
Flaxseed
,
Ghee
,
Shorea robusta
,
Zinc
Diseases
:
Aging Skin
,
Wound Healing: Delayed
Additional Keywords
:
Ayurvedic Formulas
,
Regenerative Substances
[+]
Active components in Nigella sativa and Olive oil may prove useful in treating impaired cognition.
Nov 20, 2016
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2016 Nov 21:1-10. Epub 2016 Nov 21. PMID:
27868798
Article Published Date
: Nov 20, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
,
Olive Oil
Diseases
:
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
[+]
Administration of either nigella sativa oil counteracts dexamethasone induced-gastric lesions.
Feb 09, 2017
Click here to read the entire abstract
Pubmed Data
: Can J Physiol Pharmacol. 2017 Feb 10. Epub 2017 Feb 10. PMID:
28187265
Article Published Date
: Feb 09, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Corticosteroid-Induced Toxicity
Pharmacological Actions
:
Anti-Ulcer Agents
,
Gastroprotective
,
Malondialdehyde Down-regulation
[+]
Administration of melatonin, retinoic acid and Nigella sativa reduced the carcinogenic effects of DMBA.
Nov 30, 2005
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Exp Pathol. 2005 Dec ;86(6):383-96. PMID:
16309544
Article Published Date
: Nov 30, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Melatonin
,
Nigella sativa (aka Black Seed)
,
Vitamin A
Diseases
:
Breast Cancer
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Anticarcinogenic Agents
Additional Keywords
:
Metabolites
,
Phytotherapy
,
Plant Extracts
[+]
Administration of Nigella sativa can be used to prevent formaldehyde induced apoptosis and epithelial damage.
Apr 30, 2017
Click here to read the entire abstract
Pubmed Data
: Niger J Clin Pract. 2017 May ;20(5):523-529. PMID:
28513508
Article Published Date
: Apr 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Formaldehyde Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Cytoprotective
Problem Substances
:
Formaldehyde
[+]
Administration of Nigella sativa seed oil exerts a protective effect against urolithiasis.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Afr J Tradit Complement Altern Med. 2016 ;13(6):204-214. Epub 2016 Sep 29. PMID:
28480381
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Urolithiasis
[+]
Alpha-linolenic acid-rich flaxseed oil ingestion increases plasma adiponectin level in rats.
Jul 01, 2008
Click here to read the entire abstract
Pubmed Data
: Int J Vitam Nutr Res. 2008 Jul-Sep;78(4-5):223-9. PMID:
19326346
Article Published Date
: Jul 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Adiponectin: Low Levels
[+]
Alteration of adipose tissue immune cell milieu towards the suppression of inflammation in high fat diet fed mice by flaxseed oil supplementation.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2019 ;14(10):e0223070. Epub 2019 Oct 17. PMID:
31622373
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
High Fat Diet
,
Inflammation
,
Insulin Resistance
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Insulin Sensitizers
,
Interleukin-10 downregulation
,
Interleukin-4 downregulation
[+]
Ameliorative effect of flaxseed and its protein on ethanol-induced hepatotoxicity.
Sep 12, 2019
Click here to read the entire abstract
Pubmed Data
: J Food Biochem. 2019 Sep 13:e13047. Epub 2019 Sep 13. PMID:
31515823
Article Published Date
: Sep 12, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Alcoholic Liver Disease
Pharmacological Actions
:
Hepatoprotective
[+]
Ameliorative effect of Nigella sativa oil and vitamin C on the thyroid gland and cerebellum.
Sep 30, 2020
Click here to read the entire abstract
Pubmed Data
: Tissue Cell. 2020 Oct ;66:101391. Epub 2020 Jun 8. PMID:
32933714
Article Published Date
: Sep 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
,
Vitamin C
Diseases
:
Thyroid Diseases
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ameliorative effects of hempseed against hypercholesterolemia associated cardiovascular changes.
Sep 12, 2019
Click here to read the entire abstract
Pubmed Data
: Nutr Metab Cardiovasc Dis. 2019 Sep 13. Epub 2019 Sep 13. PMID:
31668458
Article Published Date
: Sep 12, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Hemp Seed
Diseases
:
Hypercholesterolemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Hypolipidemic
[+]
An extract of fructus cannabis ameliorates learning and memory impairment induced by d-galactose.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2017 ;2017:4757520. Epub 2017 Oct 19. PMID:
29234402
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Hemp Seed
Diseases
:
Memory Disorders
Pharmacological Actions
:
Neuroprotective Agents
[+]
Animal's studies showed that oxidized oils decreased the whole body weight, which was ameliorated by the co-administration of un-oxidized oils.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Chem. 2017 ;5:55. Epub 2017 Jul 26. PMID:
28798910
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pumpkin Seed Oil/Meal
[+]
Antidepressant-like effect of flaxseed secoisolariciresinol diglycoside in ovariectomized mice subjected to unpredictable chronic stress.
Dec 21, 2012
Click here to read the entire abstract
Pubmed Data
: Metab Brain Dis. 2012 Dec 22. Epub 2012 Dec 22. PMID:
23263992
Article Published Date
: Dec 21, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Depression
,
Ovariectomy Associated Adverse Changes
,
Postmenopausal Disorder: Brain/Nervous System Pathology
Pharmacological Actions
:
Antidepressive Agents
Anti Therapeutic Actions
:
Stress
[+]
Beneficial effect of flax seeds in streptozotocin (STZ) induced diabetic mice: isolation of active fraction having islet regenerative and glucosidase inhibitory properties.
Apr 30, 2013
Click here to read the entire abstract
Pubmed Data
: Can J Physiol Pharmacol. 2013 May ;91(5):325-31. Epub 2013 Jan 16. PMID:
23656171
Article Published Date
: Apr 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Diabetes Mellitus: Type 1
Pharmacological Actions
:
Regenerative
Additional Keywords
:
Beta Cell Regeneration
[+]
Beneficial effects of flaxseed and its components on mammary gland MiRNome.
Nov 03, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Nov 4 ;11(11). Epub 2019 Nov 4. PMID:
31689992
Article Published Date
: Nov 03, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Breast Cancer
Pharmacological Actions
:
Chemopreventive
,
MicroRNA modulator
Additional Keywords
:
Risk Reduction
[+]
Beneficial effects of flaxseed polysaccharides on metabolic syndrome.
Apr 30, 2020
Click here to read the entire abstract
Pubmed Data
: Food Res Int. 2020 May ;131:108994. Epub 2020 Jan 10. PMID:
32247451
Article Published Date
: Apr 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Metabolic Syndrome X
,
Obesity
Pharmacological Actions
:
Gastrointestinal Agents
,
Hypolipidemic
Additional Keywords
:
Anti-Obesity Agents
[+]
Beneficial effects of pumpkin seed oil as a topical hair growth promoting agent in a mice model.
Oct 31, 2019
Click here to read the entire abstract
Pubmed Data
: Avicenna J Phytomed. 2019 Nov-Dec;9(6):499-504. PMID:
31763209
Article Published Date
: Oct 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Pumpkin Seed Oil/Meal
Diseases
:
Alopecia
,
Hair Loss
Additional Keywords
:
Hair Regeneration
[+]
Bisphenol A-induced oxidative damage in the hepatic and cardiac tissues of rats: The modulatory role of sesame lignans.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2020 Jan ;19(1):33-44. Epub 2019 Nov 13. PMID:
31853270
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Sesame Seeds
Diseases
:
Bisphenol Toxicity
Pharmacological Actions
:
Cardioprotective
,
Hepatoprotective
Problem Substances
:
Bisphenol A
[+]
Black cumin exhibit significant antifungal activity against candidasis in mice.
Feb 01, 2003
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2003 Feb;17(2):183-6. PMID:
12601685
Article Published Date
: Feb 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Candidiasis
,
Fungal Infection
Pharmacological Actions
:
Antifungal Agents
Additional Keywords
:
Plant Extracts
[+]
Black cumin extract reduces the damage caused by cadmium poisoning in rats.
May 01, 2006
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2006 May;110(2):151-62. PMID:
16757843
Article Published Date
: May 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Cadmium Poisoning
[+]
Black Cumin improves blood lipid profiles.
Oct 04, 2010
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2010 Oct 4;482(3):183-7. Epub 2010 Jun 11. PMID:
16092657
Article Published Date
: Oct 04, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Cholesterol: LDL/HDL ratio
,
HDL: Low
,
High Cholesterol
[+]
Black cumin may have antidiabetic effects by increasing insulin sensitivity.
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: Evid Based Complement Alternat Med. 2011;2011:538671. Epub 2011 Apr 14. PMID:
21584245
Article Published Date
: Jan 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Diabetes Mellitus: Type 2
,
Insulin Resistance
Pharmacological Actions
:
Insulin Sensitizers
[+]
Black cumin oil decreased the proinflammatory cytokines, lactate dehydrogenase, triglyceride, and cholesterol, which were increased in colitis.
Feb 28, 2011
Click here to read the entire abstract
Pubmed Data
: Dig Dis Sci. 2011 Mar ;56(3):721-30. Epub 2010 Jul 24. PMID:
20658190
Article Published Date
: Feb 28, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Oxidative Stress
,
Ulcerative Colitis
Pharmacological Actions
:
Antioxidants
,
Hypolipidemic
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Oils
[+]
Black cumin protects against chemical weapon agent induced lung injury.
May 01, 2008
Click here to read the entire abstract
Pubmed Data
: Exp Lung Res. 2008 May;34(4):183-94. PMID:
18432455
Article Published Date
: May 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Chemical Weapon Agent Injury
Additional Keywords
:
Plant Extracts
[+]
Black cumin seed oil has significant protective activity against cytomegalovirus infection in the mouse experimental model.
Sep 01, 2000
Click here to read the entire abstract
Pubmed Data
: Int J Immunopharmacol. 2000 Sep;22(9):729-40. PMID:
10884593
Article Published Date
: Sep 01, 2000
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Cytomegalovirus Infections
Pharmacological Actions
:
Antiviral Agents
,
Interferon Inducers
[+]
Black cumin's hyperglycemic activity in the rat model of diabetes may be due to beta cell regeneration/proliferation.
Dec 01, 2003
Click here to read the entire abstract
Pubmed Data
: Tohoku J Exp Med. 2003 Dec;201(4):213-9. PMID:
14690013
Article Published Date
: Dec 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Diabetes Mellitus: Type 1
Additional Keywords
:
Beta Cell Regeneration
[+]
Black seed oil exhibited an anti-aging effect in a model of aging induced with D-galactose.
Feb 28, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Pharmacopuncture. 2017 Mar ;20(1):29-35. PMID:
28392960
Article Published Date
: Feb 28, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Aging
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
[+]
Black seed oil has significant inhibitory effects against colon cancer in rats, without observable side effects.
Jan 01, 2003
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2003;45(2):195-202. PMID:
12881014
Article Published Date
: Jan 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
[+]
Black seed thymoquinone improved insulin secretion, hepatic glycogen storage, and oxidative stress in streptozotocin-induced diabetic male wistar rats.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2018 ;2018:8104165. Epub 2018 Mar 4. PMID:
29686746
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
,
Thymoquinone
Diseases
:
Diabetes: Oxidative Stress
,
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Antioxidants
,
Insulin-releasing
[+]
Bone marrow-derived mesenchymal stem cells and N.sativa ameliorate the histological, biochemical and immunohistochemical changes induced by energy drink.
Jun 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Folia Morphol (Warsz). 2019 Jul 1. Epub 2019 Jul 1. PMID:
31257565
Article Published Date
: Jun 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Pharmacological Actions
:
Pancreato Protective Agents
Additional Keywords
:
Mesenchymal Stem Cells
Problem Substances
:
Energy Drinks
[+]
Both Nigella sativa and date reduce the toxic effects of aflatoxin-B1 in liver and kidney.
Jun 30, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Health Sci (Qassim). 2008 Jul ;2(2):26-44. PMID:
21475486
Article Published Date
: Jun 30, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Dates
,
Nigella sativa (aka Black Seed)
Diseases
:
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Hepatoprotective
,
Renoprotective
Problem Substances
:
Aflatoxin
[+]
Both Nigella sativa and thymoquinone can partly protect gastric mucosa from acute alcohol-induced mucosal injury.
Nov 13, 2005
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Gastroenterol. 2005 Nov 14 ;11(42):6662-6. PMID:
16425361
Article Published Date
: Nov 13, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
,
Thymoquinone
Diseases
:
Alcohol Toxicity
Pharmacological Actions
:
Gastroprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Both Nigella sativa fixed and essential oil are effective in improving the antioxidant indices against potassium bromate induced oxidative stress.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2015 ;15(1):330. Epub 2015 Sep 18. PMID:
26385559
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Essential Oils
[+]
Both Nigella sativa oil and thymoquinone possess gastroprotective effect against gastric lesions.
Jan 31, 2003
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2003 Feb ;84(2-3):251-8. PMID:
12648823
Article Published Date
: Jan 31, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
,
Thymoquinone
Diseases
:
Ischemia
,
Lipid Peroxidation
Pharmacological Actions
:
Anti-Ulcer Agents
,
Gastroprotective
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Oils
[+]
Cardioprotective effects of dietary flaxseed post-infarction are associated with changes in microRNA expression.
Sep 07, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomolecules. 2020 Sep 8 ;10(9). Epub 2020 Sep 8. PMID:
32911872
Article Published Date
: Sep 07, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Cardioprotective
,
MicroRNA modulator
[+]
Celery oil seed extract ameliorated the toxicological effects of DEHP in rats.
Mar 31, 2015
Click here to read the entire abstract
Pubmed Data
: Toxicol Ind Health. 2015 Apr ;31(4):355-66. Epub 2013 Feb 1. PMID:
23377116
Article Published Date
: Mar 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Celery Oil
,
Celery seed
Diseases
:
Phthalate Toxicity
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
Additional Keywords
:
Plant Extracts
Problem Substances
:
Phthalates
[+]
Celery seed extract can be effective in controlling hyperglycemia and hyperlipidemia in diabetic rats.
Mar 03, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Acta Diabetol. 2016 Mar 4. Epub 2016 Mar 4. PMID:
26940333
Article Published Date
: Mar 03, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Celery
,
Celery seed
Diseases
:
Hyperglycemia
,
Hyperlipidemia
Pharmacological Actions
:
Hypoglycemic Agents
,
Hypolipidemic
Additional Keywords
:
Plant Extracts
[+]
Celery seed extract has a chemopreventive action against benzo[a]pyrene-induced forestomach cancer in mice.
Jan 01, 1993
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 1993 ;19(1):77-86. PMID:
8446516
Article Published Date
: Jan 01, 1993
Study Type
: Animal Study
Additional Links
Substances
:
Celery seed
Diseases
:
Benzo[a]pyrene-induced Toxicity
,
Gastric Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Celery seed extract has a potent protective action against chemically induced liver cancer
Apr 18, 2005
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 2005 Apr 18;221(1):11-20. PMID:
15797622
Article Published Date
: Apr 18, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Celery seed
Diseases
:
Liver Cancer
[+]
Chondroprotective effect of Nigella sativa oil in the early stages of osteoarthritis.
Aug 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Musculoskelet Neuronal Interact. 2019 Sep 1 ;19(3):362-369. PMID:
31475944
Article Published Date
: Aug 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Chondroprotective
[+]
Chronic administration of N. sativa seed extract has a significant hypoglycemic effect.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Avicenna J Phytomed. 2016 Jan-Feb;6(1):67-76. PMID:
27247923
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Diabetic Complications
,
Endothelial Dysfunction
Pharmacological Actions
:
Hypoglycemic Agents
[+]
Cold-pressed Nigella Sativa oil standardized to 3% thymoquinone potentiates omega-3 protection against obesity.
Jun 03, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2020 Jun 4 ;9(6). Epub 2020 Jun 4. PMID:
32512788
Article Published Date
: Jun 03, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
,
Omega-3 Fatty Acids
,
Thymoquinone
Diseases
:
Insulin Resistance
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Anti-Obesity Agents
[+]
Comparative hepatoprotective effect of Nigella sativa pre- and post-treatment.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2019 Jan ;32(1):205-212. PMID:
30772810
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Prophylactic Agents
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Compounds from cumin were found to have antiglycative effects greater than aminoguanidine, a synthetic antiglycative agent.
Nov 24, 2015
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2015 Nov 25 ;63(46):10097-102. Epub 2015 Nov 17. PMID:
26548586
Article Published Date
: Nov 24, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Cumin
Diseases
:
Advanced Glycation End products (AGE)
Pharmacological Actions
:
Anti-Glycation Agents
Additional Keywords
:
Superiority of Natural Substances versus Drugs
[+]
Covering peritoneal surfaces with nigella sativa oil after peritoneal trauma is effective in decreasing peritoneal adhesion formation.
Oct 06, 2013
Click here to read the entire abstract
Pubmed Data
:
J Obstet Gynaecol Res.
2013 Oct 7. doi: 10.1111/jog.12172.
Article Published Date
: Oct 06, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Abdominal Adhesions
[+]
Cumin and black pepper prevent chemically-induced rat colon carcinogenesis.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2006;9(2):237-45. PMID:
16822210
Article Published Date
: Jan 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Black Pepper
,
Cumin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
Cumin contains a compound cuminaldehyde which may contribute to this herb's antidiabetic activity.
Apr 06, 2005
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2005 Apr 6;53(7):2446-50. PMID:
15796577
Article Published Date
: Apr 06, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Cumin
Diseases
:
Diabetes Mellitus: Type 2
[+]
Cumin essential oil led to significant improvement in the sperm count, motility and viabilityin mice with copper poisoning.
Aug 30, 2015
Click here to read the entire abstract
Pubmed Data
: Andrologia. 2015 Aug 31. Epub 2015 Aug 31. PMID:
26332396
Article Published Date
: Aug 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Cumin
Diseases
:
Copper Toxicity
Pharmacological Actions
:
Cytoprotective
Additional Keywords
:
Essential Oils
[+]
Cumin extract reverses bone loss in ovariectomized rats as well as estradiol.
Sep 29, 2008
Click here to read the entire abstract
Pubmed Data
: Exp Biol Med (Maywood). 2008 Sep 29. PMID:
18824723
Article Published Date
: Sep 29, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Cumin
Diseases
:
Osteoporosis
Additional Keywords
:
Natural Substances Versus Drugs
[+]
Cumin has antistress, antioxidant, and memory-enhancing activities.
Jul 01, 2011
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2011 Jul ;49(7):702-8. PMID:
21639683
Article Published Date
: Jul 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Cumin
Diseases
:
Memory Disorders: Drug-Induced
,
Memory Loss
,
Oxidative Stress
,
Stress
[+]
Cumin has blood sugar lowering and anti-glycation properties supeior to the drug glibenclamide.
Aug 01, 2010
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2030-6. Epub 2010 May 6. PMID:
20451573
Article Published Date
: Aug 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Cumin
Diseases
:
Advanced Glycation End products (AGE)
,
Diabetes: Gestational
,
Diabetes: Oxidative Stress
,
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Antioxidants
,
Hypoglycemic Agents
Additional Keywords
:
Drug: Glibenclamide
,
Natural Substances Versus Drugs
,
Plant Extracts
[+]
Cumin has reversible contraceptive activities in male rats without apparent toxicity.
Jul 01, 2011
Click here to read the entire abstract
Pubmed Data
: Contraception. 2011 Jul ;84(1):98-107. Epub 2011 Feb 16. PMID:
21664518
Article Published Date
: Jul 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Cumin
Diseases
:
Infertility: Male
Pharmacological Actions
:
Contraceptive Agents: Male
[+]
Cumin is a potent immunomodulator and may develop as a lead to recover the immunity of immuno-compromised individuals.
Feb 12, 2010
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2010 Feb 12. Epub 2010 Feb 12. PMID:
20156427
Article Published Date
: Feb 12, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Cumin
Diseases
:
Immune Disorders: Low Immune Function
,
Stress
Pharmacological Actions
:
Immunomodulatory
[+]
Cumin prevents glycation of the diabetic lens, delaying cataracts in the rat experimental model.
Sep 10, 2008
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2008 Sep 10. PMID:
18789666
Article Published Date
: Sep 10, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Cumin
Diseases
:
Cataract
[+]
Cumin reduces morphine-induced conditioned place preference (CPP) in mice.
Sep 01, 1999
Click here to read the entire abstract
Pubmed Data
: Wound Repair Regen. 1999 Sep-Oct;7(5):362-74. PMID:
18950682
Article Published Date
: Sep 01, 1999
Study Type
: Animal Study
Additional Links
Substances
:
Cumin
Diseases
:
Morphine Tolerance/Dependence
[+]
Cumin seed has significant anti-tumor activity in the mouse model.
Jan 01, 2003
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2003;47(2):171-80. PMID:
15087270
Article Published Date
: Jan 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Cumin
Diseases
:
Cervical Cancer
[+]
Cumin seeds improves blood lipid profiles, blood sugar and glycation in diabetic rats more effectively than glibenclamide.
Sep 01, 2002
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2002 Sep;46(3):251-5. PMID:
12220968
Article Published Date
: Sep 01, 2002
Study Type
: Animal Study
Additional Links
Substances
:
Cumin
Diseases
:
Diabetes: Lipids/Cholesterol
,
Diabetes Mellitus: Type 1
Additional Keywords
:
Alloxan-Induced Diabetes
,
Superiority of Natural Substances versus Drugs
[+]
Dietary flax oil and feeding moderates renal injury in a rat model of polycystic kidney disease.
Nov 01, 2002
Click here to read the entire abstract
Pubmed Data
: Lipids. 2002 Nov;37(11):1059-65. PMID:
12558056
Article Published Date
: Nov 01, 2002
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Polycystic Kidney Diseases
[+]
Dietary flaxseed enhances the inhibitory effect of tamoxifen on the growth of estrogen-dependent human breast cancer in mice.
Aug 01, 2001
Click here to read the entire abstract
Pubmed Data
: Acta Pharmacol Sin. 2001 Aug;22(8):756-60. PMID:
15570004
Article Published Date
: Aug 01, 2001
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Breast Cancer
Additional Keywords
:
Drug-Plant-Vitamin Synergies
,
Synergy with Tamoxifen
[+]
Dietary flaxseed interacts positively with tamoxifen to induce breast tumor regression.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2007;58(2):162-70. PMID:
17640162
Article Published Date
: Jan 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Breast Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Drug: Tamoxifen
,
Drug-Plant-Vitamin Synergies
[+]
Dietary flaxseed lignan or oil increases the breast cancer inhibitory effects of Tamoxifen.
Nov 01, 2006
Click here to read the entire abstract
Pubmed Data
: Biol Psychiatry. 2006 Nov 1;60(9):987-90. Epub 2006 Feb 24. PMID:
19904759
Article Published Date
: Nov 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Breast Cancer
Pharmacological Actions
:
Selective estrogen enzyme modulator (SEEM)
,
Selective Estrogen Receptor Modulators
Additional Keywords
:
Drug-Plant-Vitamin Synergies
[+]
Dietary flaxseed may be chemopreventive for intestinal and colon tumor development in mice possibly by increasing omega -3 fatty acid levels, lignans, and decreasing COX-1 and COX-2 levels.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2009;61(2):276-83. PMID:
19235044
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
,
Lignans
,
Omega-3 Fatty Acids
Diseases
:
Colon Cancer
,
Intestinal Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Cyclooxygenase 1 Inhibitor
,
Cyclooxygenase 2 Inhibitors
,
Cyclooxygenase Inhibitors
[+]
Dietary flaxseed meal containing high levels of omega-3 fatty acids and lignans is effective in preventing colon tumor development when compared with dietary corn meal possibly by increasing omega-3 fatty acid levels and decreasing COX-1 and COX-2 levels.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2006;54(2):216-22. PMID:
16898866
Article Published Date
: Jan 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
,
Lignans
,
Omega-3 Fatty Acids
Diseases
:
Colon Cancer
Pharmacological Actions
:
Cyclooxygenase 1 Inhibitor
,
Cyclooxygenase 2 Inhibitors
[+]
Dietary flaxseed meal is more protective than soy protein concentrate against hypertriglyceridemia and fatty liver in an animal model of obesity.
Apr 01, 2003
Click here to read the entire abstract
Pubmed Data
: J Am Coll Nutr. 2003 Apr;22(2):157-64. PMID:
12672712
Article Published Date
: Apr 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Diabetes Mellitus: Type 2
,
Fatty Liver
,
Obesity
,
Triglycerides: Elevated
Pharmacological Actions
:
Anticholesteremic Agents
,
Hypolipidemic
[+]
Dietary flaxseed meal reduces proteinuria and ameliorates nephropathy in an animal model of type 2 diabetes mellitus.
Dec 01, 2003
Click here to read the entire abstract
Pubmed Data
: Kidney Int. 2003 Dec;64(6):2100-7. PMID:
14633132
Article Published Date
: Dec 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Diabetes Mellitus: Type 2
,
Proteinuria
[+]
Dietary flaxseed oil protects against bleomycin-induced pulmonary fibrosis in rats.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Pulm Med. 2012 ;2012:457031. Epub 2012 Aug 8. PMID:
22919480
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Chemotherapy-Induced Toxicity: Bleomycin
,
Pulmonary Fibrosis: Bleomycin-Induced
Problem Substances
:
Bleomycin
[+]
Dietary flaxseed oil rich in omega-3 suppresses severity of type 2 diabetes mellitus via anti-inflammation and modulating gut microbiota.
Feb 06, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Lipids Health Dis. 2020 Feb 7 ;19(1):20. Epub 2020 Feb 7. PMID:
32028957
Article Published Date
: Feb 06, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Dietary flaxseed oil supplementation ameliorates cisplatin-induced intestinal damage.
Jul 01, 2012
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2012 Jul 2. Epub 2012 Jul 2. PMID:
22751286
Article Published Date
: Jul 01, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Problem Substances
:
Cisplatin
[+]
dietary flaxseed oil, containing high levels of omega-3 fatty acids, is effective in preventing colon tumor development when compared with dietary corn oil containing omega-6 fatty acids in rats.
May 01, 2008
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2008 May;74(6):686-92. Epub 2008 Apr 30. PMID:
15749630
Article Published Date
: May 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
,
Omega-3 Fatty Acids
Diseases
:
Colon Cancer
Additional Keywords
:
Omega 3/6 Ratio
,
Omega 6 Fatty Acids are Detrimental
[+]
Dietary flaxseed prevents radiation-induced oxidative lung damage, inflammation and fibrosis in a mouse model of thoracic radiation injury.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Cancer Biol Ther. 2009 Jan;8(1):47-53. Epub 2009 Jan 1. PMID:
18981722
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Radiation Induced Illness: Thoracic
[+]
Dietary flaxseed supplementation ameliorates signs of polycystic kidney disease.
Jan 01, 1998
Click here to read the entire abstract
Pubmed Data
: Biochem Cell Biol. 1998;76(2-3):553-9. PMID:
9923725
Article Published Date
: Jan 01, 1998
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Polycystic Kidney Diseases
[+]
Dietary flaxseed supplementation may be an effective chemoprevention strategy for chemically induced lung carcinogenesis.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Cancer Prev Res (Phila). 2018 Jan ;11(1):27-37. Epub 2017 Oct 26. PMID:
29074535
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Antioxidants
,
Chemopreventive
,
Phase II Detoxification Enzyme Inducer
[+]
Dietary hemp seeds more effectively attenuate metabolic disorders in genetically obese rats than the oil extracted from them.
May 31, 2020
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2020 Jun 1 ;150(6):1425-1433. PMID:
32275310
Article Published Date
: May 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Hemp Seed
Diseases
:
Obesity
Pharmacological Actions
:
Hypolipidemic
Additional Keywords
:
Anti-Obesity Agents
[+]
Dietary phytochemicals have a beneficial effect on benign prostatic hyperplasia prevention.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Appl Physiol Nutr Metab. 2016 Dec ;41(12):1303-1310. Epub 2016 Sep 27. PMID:
27849354
Article Published Date
: Nov 30, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flaxseed
,
Lignans
Diseases
:
Prostatic Hyperplasia: Benign
Pharmacological Actions
:
Antiproliferative
,
Cell cycle arrest
,
Cyclin D1 Down-Regulation
,
Tumor Suppressor Protein p53 Upregulation
[+]
Dietary soy protein and flax oil reduces some disease-associated pathologies in established renal disease.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: Nephron Exp Nephrol. 2007;106(4):e122-8. Epub 2007 Jun 29. PMID:
17622740
Article Published Date
: Jan 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
,
Soy Protein
Diseases
:
Kidney Diseases
,
Polycystic Kidney Diseases
[+]
Effects of Nigella sativa and human parathyroid hormone on bone mass and strength in diabetic rats.
May 31, 2007
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2007 Jun ;116(3):321-8. PMID:
17709912
Article Published Date
: May 31, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Diabetic Complications
,
Osteoporosis
Pharmacological Actions
:
Osteoprotective
Additional Keywords
:
Plant Extracts
[+]
Effects of Nigella sativa seed polysaccharides on type 2 diabetic mice and gut microbiota.
May 07, 2020
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2020 May 8 ;159:725-738. Epub 2020 May 8. PMID:
32437806
Article Published Date
: May 07, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Gastrointestinal Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Polysaccharides
[+]
Efficient therapeutic effect of Nigella sativa aqueous extract and chitosan nanoparticles against experimentally induced acanthamoeba keratitis.
May 28, 2019
Click here to read the entire abstract
Pubmed Data
: Parasitol Res. 2019 May 29. Epub 2019 May 29. PMID:
31144032
Article Published Date
: May 28, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Keratitis
Additional Keywords
:
Significant Treatment Outcome
[+]
Ellagic acid and pumpkin seed oil protects against methotrexate-induced small intestine damage in rats.
Nov 30, 2011
Click here to read the entire abstract
Pubmed Data
: Indian J Biochem Biophys. 2011 Dec ;48(6):380-7. PMID:
22329239
Article Published Date
: Nov 30, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Ellagic Acid
,
Pumpkin Seed Oil/Meal
Diseases
:
Drug Toxicity: Methotrexate
,
Gastrointestinal Hemorrhage
Pharmacological Actions
:
Gastroprotective
[+]
Enterolactone and enterodiol have been shown to negate the tumor-stimulating effect of genistein in a mouse model of breast cancer.
Jul 01, 2007
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2007 Jul;51(7):845-56. PMID:
17579892
Article Published Date
: Jul 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Enterodiol
,
Enterolactone
,
Flaxseed
,
Genistein
,
Isoflavones
,
Lignans
,
phytoestrogens
,
Soy Protein
Diseases
:
Breast Cancer
,
Breast Cancer: Prevention
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
[+]
Essential oils of green cumin and chamomile partially protect against acute acetaminophen hepatotoxicity in rats.
Jul 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: An Acad Bras Cienc. 2018 Aug ;90(2 suppl 1):2347-2358. Epub 2018 Jun 25. PMID:
29947676
Article Published Date
: Jul 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Chamomile
,
Cumin
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Ethanolic extract of Nigella sativa possessed significant analgesic effect in mice.
Jun 30, 2010
Click here to read the entire abstract
Pubmed Data
: J Coll Physicians Surg Pak. 2010 Jul ;20(7):464-7. PMID:
20642947
Article Published Date
: Jun 30, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Chronic Pain
Pharmacological Actions
:
Analgesics
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Feeding hen’s hemp products effectively increased n-3 polyunsaturated fatty acids in total lipids, triacylglycerol and phospholipid of egg yolk.
Oct 28, 2015
Click here to read the entire abstract
Pubmed Data
: Lipids. 2015 Oct 29. Epub 2015 Oct 29. PMID:
26515300
Article Published Date
: Oct 28, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Hemp Seed
[+]
Feeding of Nigella sativa during neonatal and juvenile growth improves learning and memory of rats.
Mar 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Tradit Complement Med. 2016 Apr ;6(2):146-52. Epub 2015 Jan 17. PMID:
27114937
Article Published Date
: Mar 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Learning disorders
,
Memory Disorders
Pharmacological Actions
:
Antioxidants
[+]
Fish oil and Nigella sative volatile oil emulsion had promising hepato-regenerative and reno-protective abilities.
Feb 18, 2018
Click here to read the entire abstract
Pubmed Data
: J Oleo Sci. 2018 Feb 19. Epub 2018 Feb 19. PMID:
29459508
Article Published Date
: Feb 18, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Fish Oil
,
Nigella sativa (aka Black Seed)
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Renoprotective
Additional Keywords
:
Liver Regeneration
[+]
Fish oil, but not flaxseed oil, decreases inflammation and prevents pressure overload-induced cardiac dysfunction.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Immunopharmacol Immunotoxicol. 2009;31(2):209-13. PMID:
19015135
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
,
Omega-3 Fatty Acids
Diseases
:
Adiponectin: Low Levels
,
Heart Failure
,
Hypertension
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Flax Versus Fish Oil
[+]
Flax and Pumpkin seeds mixture supplemented in diet of diabetic rats may be helpful to prevent diabetes and its complications.
Jul 31, 2010
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2407-12. Epub 2010 Jun 4. PMID:
20570704
Article Published Date
: Jul 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
,
Pumpkin
Diseases
:
Diabetic Nephropathy
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
[+]
Flax oil influences honey bee nestmate recognition.
Jul 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Econ Entomol. 2012 Aug ;105(4):1145-8. PMID:
22928291
Article Published Date
: Jul 31, 2012
Study Type
: Insect Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Bee Colony Collapse
[+]
Flax seed oil appears to have a beneficial effects on the sperm quality and reproductive health of buffalo bull.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Anim Sci Technol. 2016 ;58:25. Epub 2016 Jul 1. PMID:
27375853
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Infertility: Male
,
Sperm Quality: Low
[+]
Flaxseed alters estrogen metabolite excretion by increasing the beneficial 2-hydroxyestrone metabolite relative to the harmful16-hydroxylestrone.
Feb 01, 2004
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2004 Feb;79(2):318-25. PMID:
14749240
Article Published Date
: Feb 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Estrogen Dysregulation: 2/4/16 hydroxyestrone ratios
[+]
Flaxseed and evening primrose oil slightly affect systolic and diastolic function of isolated heart in males.
Nov 07, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Vitam Nutr Res. 2019 Nov 8:1-9. Epub 2019 Nov 8. PMID:
31699009
Article Published Date
: Nov 07, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Evening Primrose Oil
,
Flaxseed
Diseases
:
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
[+]
Flaxseed and its lignans have potent antiestrogenic effects on estrogen receptor-positive breast cancer and may prove to be beneficial in breast cancer prevention strategies in the future.
Feb 01, 2007
Click here to read the entire abstract
Pubmed Data
: Clin Cancer Res. 2007 Feb 1;13(3):1061-7. PMID:
17289903
Article Published Date
: Feb 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Enterodiol
,
Enterolactone
,
Flaxseed
,
Lignans
Diseases
:
Breast Cancer
,
Breast Cancer: Prevention
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Vascular Endothelial Growth Factor A Inhibitor
[+]
Flaxseed extract exhibits mucosal protective effect in acetic acid induced colitis in mice .
Jun 05, 2016
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2016 Jun 6 ;38:153-166. Epub 2016 Jun 6. PMID:
27280586
Article Published Date
: Jun 05, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Colitis
[+]
Flaxseed has a chemopreventive effect on ovarian cancer and increased survival in hens.
Feb 12, 2010
Click here to read the entire abstract
Pubmed Data
: Gynecol Oncol. 2010 Feb 12. Epub 2010 Feb 12. PMID:
20153884
