Soy

Name	AC	CK
Breast Cancer	47	187
Prostate Cancer	31	141
Postmenopausal Disorders	15	117
Osteoporosis	17	107
Endothelial Dysfunction	9	81
Diabetes Mellitus: Type 2	11	69
Lung Cancer	11	68
Hypothyroidism	4	64
C-Reactive Protein	7	62
Hypertension	9	59
Coronary Artery Disease	3	52
Inflammation	11	50
Osteopenia	9	50
Prostate: PSA Doubling	5	50
Aging Skin	8	48
Cardiovascular Diseases	9	47
Insulin Resistance	10	47
Obesity	16	43
Cardiac Mortality	2	42
Hyperlipidemia	4	40
Breast Cancer: Prevention	7	38
Ovarian Cancer	8	38
Cholesterol: Oxidation	3	31
Hot Flash	4	31
Hemodialysis	2	30
Metabolic Syndrome X	6	30
Prostate Cancer: Prevention	3	30
Proteinuria	3	30
Colon Cancer	12	27
Cancers: Drug Resistant	6	25
Menopausal Syndrome	5	25
Asthma	4	24
Depression	4	23
Estrogen Dominance	5	23
Diabetes: Cardiovascular Illness	3	22
Alzheimer's Disease	15	21
Endometrial Cancer	3	21
Prostatic Hyperplasia: Benign	2	21
Allergic Rhinitis	2	20
Depression: Postmenopausal	2	20
Gluten Sensitivity	1	20
Kidney Transplant	2	20
Lower Urinary Tract Symptoms	1	20
Non-Small-Cell Lung Carcinoma	1	20
Osteoarthritis: Hip	2	20
Postmenopausal Complications	1	20
Sexual Development: Dysfunctions and Abnormalities	2	20
Aging	6	19
Fatty Liver	3	18
Osteoarthritis	7	18
Estrogen Deficiency	5	17
Radiation Induced Illness	5	17
Nonalcoholic fatty liver disease (NAFLD)	4	15
Androgen-Induced Diseases	3	14
High Cholesterol	2	14
Liver Cancer	13	14
Abdominal Obesity (Midsection Fat)	3	13
Adiponectin: Low Levels	3	13
Pancreatic Cancer	11	13
Bone Fractures	2	12
Endotoxemia	2	12
Fibroids: Uterine	3	12
Infertility: Male	2	12
Myocardial Infarction	2	12
Perimenopausal Syndrome	2	12
Prenatal Nutrition	2	12
Rotavirus Infections	3	12
Breast Cancer: Triple Negative	6	11
Cancers: All	11	11
Cervical Cancer	9	11
Hepatic Steatosis	2	11
Lipopolysaccharide-Induced Toxicity	8	11
Periodontal Diseases	2	11
Skin Diseases: Photo-Aging	2	11
Thrombosis	2	11
Acute Myeloid Leukemia	1	10
Acute lymphoblastic leukemia (ALL)	1	10
Addison's Disease	1	10
Aneurysm	1	10
Aneurysm: Cerebral	1	10
Athletic Performance	1	10
COPD	1	10
Cerebral Aneurysm	1	10
Chemotherapy Induced Myelotoxicity	1	10
Chronic Obstructive Pulmonary Disease	1	10
Cognitive Decline/Dysfunction	5	10
Colorectal Cancer	1	10
Colorectal Cancer: Prevention	1	10
Diabetes Mellitus: Type 2: Prevention	1	10
Diabetic Complications	6	10
Endocrine Cancer	1	10
Estradiol: Too High	1	10
Estrogen Dysregulation: 2/4/16 hydroxyestrone ratios	1	10
Fibrocystic Breast Disease	1	10
Gastroesophageal Reflux	1	10
Heart Rate Variability: Increased	1	10
Hip Fracture	1	10
Hormone Imbalances	1	10
Hypercholesterolemia	1	10
Infant Infections	1	10
Ischemic Heart Disease	1	10
Liver: Fatty	1	10
Memory Loss	1	10
Menarche: Early Onset	1	10
Multiple Myeloma: Prevention	1	10
Organ Transplantation: Kidney	1	10
Osteoarthritis: Knee	1	10
Overweight	1	10
Premenstrual syndrome	1	10
Prostatic intraepithelial neoplasia (PIN)	1	10
Sarcopenia	1	10
Stroke: Prevention	1	10
Testosterone: Too High	1	10
Urogenital Symptoms	1	10
Vaginal Atrophy	1	10
Vaginal Diseases	1	10
Vaginal Dryness	1	10
Weight Probems: Appetite	1	10
Brain Inflammation	5	9
Neurodegenerative Diseases	6	9
Oxidative Stress	8	9
Chemically-Induced Liver Damage	3	8
High Fat Diet	4	8
Hyperglycemia	4	8
Prenatal Nutrition: Health of the Offspring	3	8
Arteriosclerosis	4	7
Bladder Cancer	5	7
Chemotherapy-Induced Toxicity: Cisplatin	3	7
Cystic Fibrosis	7	7
Kidney Diseases	3	6
Memory Impairment: Hormone Deficiency Induced	3	6
Seizures	2	6
Cancer Metastasis	4	5
Glioblastoma	4	5
Hyperpigmentation	1	5
Ischemia	3	5
Melanoma	4	5
Parkinson's Disease	3	5
Advanced Glycation End products (AGE)	3	4
Aging: Immunosenecence	2	4
Autoimmune Diseases	2	4
Cerebral Ischemia	2	4
Cholesterol: High	1	4
Coronavirus Infection	3	4
Corticosteroid-Induced Toxicity	2	4
Inflammatory Bowel Diseases	2	4
Intima Media Thickening	2	4
Learning disorders	2	4
Liver Disease	1	4
Low Testosterone	2	4
Lupus Erythematosus: Systemic	2	4
Neurotoxicity	1	4
Osteoporosis: Male	2	4
Ovariectomy Associated Adverse Changes	2	4
Overactive Bladder	1	4
Prostatitis: Acute	1	4
Prostatitis: Chronic	1	4
Pulmonary Hypertension	2	4
Triglycerides: Elevated	1	4
Arenaviral Hemorrhagic Fever	2	3
Atherosclerosis	2	3
Bisphenol-A Toxicity	2	3
Breast Cancer: Chemically-Induced	2	3
Chemotherapy-Induced Toxicity: Doxorubicin	2	3
Congenital Hypothyroidism	1	3
Diabetes Mellitus: Type 1	2	3
HIV Infections	3	3
Human Papillomavirus (HPV)	2	3
Hypoxia	2	3
Kidney Cancer	2	3
Liver Cancer: Metastatic	2	3
Lymphoma	3	3
Mucopolysaccharidoses	2	3
Multiple Sclerosis	2	3
Osteonecrosis	2	3
Psoriasis	2	3
Squamous cell carcinoma	2	3
Thyroid Cancer	2	3
Wound Healing	2	3
Acetaminophen (Tylenol) Toxicity	1	2
Acrylamide-induced toxicity	1	2
Alcohol Toxicity	1	2
Allergies	1	2
Amyotrophic Lateral Sclerosis	1	2
Amyotrophic lateral sclerosis (ALS)	1	2
Androgen Deficiency	1	2
Arterial Plaque	1	2
Asthma: Bronchial	1	2
Atopic Dermatitis	1	2
B-cell prolymphocytic leukemia (B-PLL)	1	2
BRCA1/BRCA2: Prevalence	1	2
Bisphenol Toxicity	1	2
Brain Edema	1	2
Breast Cancer: Metastatic	1	2
Burns	1	2
Cancer Stem Cells	2	2
Cancers: Multi-Drug Resistant	2	2
Cardiomyopathy	1	2
Colitis	1	2
Colon Cancer: Prevention	1	2
Coronavirus Disease	1	2
Cortisone Toxicity	1	2
DNA damage	2	2
Dementia	1	2
Diabetes	1	2
Diabetes Mellitus: Type 1: Prevention	1	2
Diabetes: Eye Disease	1	2
Diabetic Neuropathies	1	2
Diabetic Retinopathy	1	2
Drug-Induced Toxicity: Indomethacin	1	2
Dyslipidemias	1	2
Encephalomyelitis	1	2
Escherichia coli Infections	1	2
Esophageal Cancer	1	2
Gastrointestinal Inflammation	1	2
Glioma	2	2
Heart Failure	1	2
Hemorrhagic Fevers: Viral	1	2
Hepatoma	1	2
High Cortisol	1	2
Hormone Replacement Therapy	1	2
Hypermethioninemia	1	2
Incontinence: Urinary	1	2
Infant Nutrition	1	2
Infertility: Aging Associated	1	2
Infertility: Female	1	2
Kidney Damage	1	2
Lead Poisoning	1	2
Leiomyoma	2	2
Leukemia: B-Cell	1	2
Leukemia: Chronic Lymphocytic Leukemia (CLL)	1	2
Lipid Peroxidation	1	2
Liver Damage	1	2
Liver Damage: Drug-Induced	1	2
Liver Fibrosis	1	2
Low DHEA	1	2
Lupus Nephritis	1	2
Malaria	1	2
Neuroblastoma	2	2
Nicotine/Tobacco Toxicity	1	2
Obsessive-Compulsive Disorder	1	2
Osteoporosis: Inflammation Induced	1	2
Osteoporosis: Steroid-Induced	1	2
Osteosarcoma	2	2
Phthalate Toxicity	1	2
Polycystic Kidney Diseases	1	2
Polycystic Ovary Syndrome	1	2
Portacaval Shunt	1	2
Post-Traumatic Stress Disorders (PTSD)	1	2
Postmenopausal Disorders: Weight Gain/Obesity	1	2
Prenatal Chemical Exposures	1	2
Radiation Induced Illness: Thoracic	1	2
Rheumatoid Arthritis	2	2
Right Ventricular Hypertrophy	1	2
Sanfilippo Syndrome	1	2
Schistosomiasis	1	2
Sciatica	1	2
Septic Shock	1	2
Shock: Septic	1	2
Skin Cancer	2	2
Sleep Disorders	1	2
Steroid-Induced Toxicity	1	2
Stroke	1	2
Stroke: Attenuation/Recovery	1	2
Stroke: Ischemic	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Traumatic Brain Injury	1	2
Tumors	1	2
Urinary Tract Cancer	1	2
5alpha-dihydrotestosterone (DHT): Elevated Levels/Activity	1	1
Adenoviridae Infections	1	1
Aluminum Toxicity	1	1
Anxiety	1	1
Aortic Stenosis	1	1
Benzo[a]pyrene-induced Toxicity	1	1
Brain Cancer	1	1
Brain: Microglial Activation	1	1
Breast Cancer: BRCA1	1	1
Breast Cancer: Estrogen	1	1
Breast Cancer: estrogen receptor alpha-positive	1	1
Carcinoma: Non-Small-Cell Lung	1	1
Cytomegalovirus Infections	1	1
Diabetes: Cataract	1	1
Diabetes: Glycation/A1C	1	1
Diabetic Nephropathy	1	1
Dialysis: Renal	1	1
Ebola Virus Infections	1	1
Endometriosis	1	1
Fibroid Tumor	1	1
Fluoride Toxicity	1	1
Gallbladder Cancer	1	1
Glioblastoma Multiforme	1	1
HIV Drug-Induced Toxicity	1	1
HSV-1	1	1
HSV-2	1	1
Head and Neck Cancer	1	1
Herpes Simplex Virus Type 2	1	1
Intestinal Permeability	1	1
Laryngeal Cancer	1	1
Leaky Gut Syndrome	1	1
Leukemia	1	1
Lymphoma: Burkitt	1	1
Mastocytoma	1	1
Multiple Myeloma	1	1
Myocarditis	1	1
Nanoparticle Toxicity: Polystyrene	1	1
Nasopharyngeal Cancer	1	1
Ovarian Cancer: Estrogen Induced	1	1
Pesticide Toxicity	1	1
Pituitary Tumours	1	1
Radiation Induced Toxicity: Polonium-120	1	1
Radiation-Induced Illness: Radioiodine (Iodine-131)	1	1
Radiotherapy	1	1
Retinoblastoma	1	1
Salivary Gland Adenoid Cystic Carcinoma.	1	1
Salivary Gland Diseases	1	1
Smoking	1	1
Staphylococcal Infections	1	1
Stomach Cancer	1	1
Testicular Cancer	1	1
Vascular Calcification	1	1

Name	AC	CK
Chemopreventive	50	315
Antioxidants	45	131
Apoptotic	67	100
Anti-Inflammatory Agents	39	87
Antiproliferative	61	81
Tumor Necrosis Factor (TNF) Alpha Inhibitor	15	67
Neuroprotective Agents	34	62
Antineoplastic Agents	14	50
Interleukin-6 Downregulation	14	47
Anticarcinogenic Agents	18	44
NF-kappaB Inhibitor	20	44
Hypoglycemic Agents	9	43
Cardioprotective	11	35
Cell cycle arrest	20	30
Matrix metalloproteinase-2 (MMP-2) inhibitor	6	28
Chemosensitizer	15	24
Gastrointestinal Agents	4	24
Antidepressive Agents	3	22
Antiviral Agents	11	22
Malondialdehyde Down-regulation	3	22
Vascular Cell Adhesion Molecule-1 Inhibitor	3	22
Anti-Apoptotic	10	18
Hepatoprotective	9	18
Enzyme Inhibitors	5	16
Gastroprotective	4	16
Anticholesteremic Agents	3	15
Chemotherapeutic	10	14
Vasodilator Agents	3	14
Hypolipidemic	3	13
Insulin Sensitizers	3	13
Insulin-Like Growth Factor Inhibition/Downregulation	3	13
MicroRNA modulator	10	13
Hypotensive	2	12
Immunomodulatory	8	12
Matrix metalloproteinase-9 (MMP-9) inhibitor	2	12
Anti-metastatic	9	11
Antihypertensive Agents	2	11
Ergogenic	1	10
Mitogen-activated protein kinase kinase 4 (MEK4)	1	10
Angiogenesis Inhibitors	6	9
Renoprotective	3	9
Chemoprotective Agents	3	8
Interleukin-1 beta downregulation	5	8
Nrf2 activation	5	8
Nitric Oxide Enhancer	2	6
Radioprotective	4	6
Radiosensitizer	6	6
Vascular Endothelial Growth Factor A Inhibitor	3	6
Pancreato Protective Agents	3	5
Tumor Suppressor Protein p53 Upregulation	4	5
Anti-Angiogenic	2	4
Cyclooxygenase 2 Inhibitors	4	4
Histone deacetylase inhibitor	3	4
Interleukin-10 downregulation	2	4
Nitric Oxide Inhibitor	2	4
Secretagogue	2	4
Vascular Endothelial Growth Factor Inhibitors	3	4
Anti-Adipogenic	3	3
Anti-Anxiety Agents	2	3
Anti-Fibrotic	2	3
Anti-Glycation Agents	2	3
Glucagon Like peptide 1 (GLP-1) Up-regulation	2	3
Heme oxygenase-1 up-regulation	2	3
Insulinotrophic	2	3
Osteoprotective	2	3
Acetylcholinesterase Down-Regulation	1	2
Alpha-glucosidase inhibitor	1	2
Cell Differentiation Inducer	2	2
Cyclin D1 Down-Regulation	2	2
Cyclooxygenase Inhibitors	1	2
Cytoprotective	1	2
Estrogen Receptor Modulators	2	2
Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Upregulation	1	2
Heme oxygenase-1 inducer	1	2
Interleukin-1 alpha downregulation	2	2
Interleukin-10 upregulation	1	2
Interleukin-8 downregulation	2	2
Lipoxygenase Inhibitors	1	2
NF-E2-Related Factor-2 (Nrf2) Modulator	1	2
Neocardiogenic	1	2
P21 Activation	2	2
Prophylactic Agents	1	2
Prostaglandin Antagonists	2	2
Protein Kinase Inhibitors	1	2
Regenerative	1	2
SIRT1 Activator	1	2
STAT3 Inhibitor	1	2
Spermatogenic	1	2
Steroidogenesis	1	2
Superoxide Dismutase Up-regulation	1	2
Anti-Androgen	1	1
Anti-Bacterial Agents	1	1
Anti-thrombotic	1	1
Antimutagenic Agents	1	1
Aromatase Inhibitors	1	1
Bax/Bcl2 ratio: Increase	1	1
Bcl-2 protein down-regulation	1	1
Bcl-xL down-regulation	1	1
Cytotoxicity	1	1
Drug synergy	1	1
Epidermal growth factor receptor (EGFR) inhibitor	1	1
Fibrinolytic Agents	1	1
Glucose transporter-1 (GLUT1) expression down-regulation	1	1
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	1	1
Interleukin-23 Downregulation	1	1
Phase II Detoxification Enzyme Inducer	1	1
Postaglandin PGE2 downregulation	1	1
Proteasome Inhibitors	1	1
Tumor Necrosis Factor (TNF) Alpha Enhancer	1	1
Tyrosinase inhibitors	1	1
Vascular Endothelial Growth Factor Regulator	1	1
Wnt/β-catenin pathway down-regulation	1	1
Wnt/β-catenin signaling pathway modulation	1	1
apoptosis	1	1

[+]

Click here to read the entire abstract

Pubmed Data : Eur Urol. 2005 Dec;48(6):922-30; discussion 930-1. Epub 2005 Oct 17. PMID: 16263208

Article Published Date : Dec 01, 2005

Study Type : Human Study

Additional Links

Substances : Antioxidant formulas, Isoflavones, Lycopene, Milk Thistle, Soy

Diseases : Prostate: PSA Doubling, Prostate Cancer

[+]

A daily supplement of soy protein prevents the increase in subcutaneous and total abdominal fat in postmenopausal women. Dec 01, 2007

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Pubmed Data : Fertil Steril. 2007 Dec;88(6):1609-17. Epub 2007 Apr 6. PMID: 17412329

Article Published Date : Dec 01, 2007

Study Type : Human Study

Additional Links

Substances : Isoflavones, Soy Protein

Diseases : Abdominal Obesity (Midsection Fat)

[+]

Click here to read the entire abstract

Pubmed Data : Nutrition. 2006 Feb;22(2):104-13. PMID: 16459222

Click here to read the entire abstract

Pubmed Data : JAMA. 2009 Dec 9;302(22):2437-43. PMID: 19996398

Click here to read the entire abstract

Pubmed Data : Can J Diabetes. 2019 Oct ;43(7):490-497. Epub 2019 May 4. PMID: 31307913

Article Published Date : Sep 30, 2019

Study Type : Human Study

Additional Links

Substances : Genistein

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Malondialdehyde Down-regulation

[+]

Effects of genistein aglycone in glucocorticoid induced osteoporosis.Jun 30, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Pharmacother. 2023 Jul ;163:114821. Epub 2023 May 9. PMID: 37167726

Article Published Date : Jun 30, 2023

Study Type : Human Study

Additional Links

Substances : Genistein

Diseases : Osteoporosis

Pharmacological Actions : Osteoprotective

Additional Keywords : Natural Substances Versus Drugs

[+]

[+]

Pubmed Data : J Gastroenterol Hepatol. 2007 Nov;22(11):2009-14. PMID: 17914984

[+]

Habitual miso consumption is associated with a low prevalence of sarcopenia in patients with type 2 diabetes.Dec 27, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2020 Dec 28 ;13(1). Epub 2020 Dec 28. PMID: 33379405

Article Published Date : Dec 27, 2020

Study Type : Human Study

Additional Links

Substances : Miso

Diseases : Diabetes Mellitus: Type 2, Sarcopenia

Additional Keywords : Risk Reduction

[+]

[+]

Click here to read the entire abstract

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2007 Feb;53(1):57-62. PMID: 17484381

Article Published Date : Feb 01, 2007

Study Type : Human Study

Additional Links

Substances : Beta-glucan, Isoflavones, Soy

Diseases : Aging Skin

[+]

Regular soy food intake may be associated with a reduced risk of breast cancer, and this effect is more pronounced in premenopausal women.Jan 01, 2008

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Pubmed Data : Nutr Cancer. 2008;60(5):568-76. PMID: 18791919

Pubmed Data : Fertil Steril. 2010 May 1;93(7):2095-104. Epub 2010 Apr 8. PMID: 20378106

Article Published Date : May 01, 2010

Study Type : Human Study

Additional Links

Substances : Isoflavones, Soy

[+]

Safety: soy food consumption lowers estrogen levels in nipple aspirate fluid and serum. Jul 08, 2011

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Pubmed Data : Cancer Sci. 2008 Jun;99(6):1202-8. Epub 2008 Apr 21. PMID: 18429954

Click here to read the entire abstract

Pubmed Data : Nutr Metab Cardiovasc Dis. 2018 Apr 10. Epub 2018 Apr 10. PMID: 29739677

Article Published Date : Apr 09, 2018

Study Type : Human Study

Additional Links

Substances : Isoflavones, Soy

Diseases : Cardiovascular Diseases, Menopausal Syndrome

Pharmacological Actions : Cardioprotective

Additional Keywords : Risk Reduction

[+]

Soy isoflavones may benefit some patients with prostate cancer. Jan 01, 2003

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Pubmed Data : Nutr Cancer. 2003;47(2):111-7. PMID: 15087261

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Pubmed Data : Hum Cell. 1999 Dec;12(4):189-96. PMID: 16255781

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Pubmed Data : Nutr Cancer. 2000;36(1):14-8. PMID: 10798211

Article Published Date : Jan 01, 2000

Study Type : Human Study

Additional Links

Substances : Soy

Diseases : Estradiol: Too High, Estrogen Dominance, Testosterone: Too High

Additional Keywords : Sex Hormone-Binding Globulin

[+]

Soy products, fiber, phytoestrogens, vegetable and fruist, and seaweed consumption reduce the risk of endomentrial cancer. Aug 15, 1997

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Pubmed Data : Am J Epidemiol. 1997 Aug 15;146(4):294-306. PMID: 9270408

Soy protein reduces cholesterol oxidation in patients on hemodialysis. Jan 01, 2006

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Pubmed Data : J Med Food. 2006;9(3):368-72. PMID: 17004900

Article Published Date : Jan 01, 2006

Study Type : Human Study

Additional Links

Substances : Daidzein, Genistein, Isoflavones, Soy Protein

Diseases : Cholesterol: Oxidation, Hemodialysis

Pharmacological Actions : Antioxidants

[+]

Soy protein with isoflavones has favorable effects on endothelial function that are independent of lipid and antioxidant effects in healthy postmenopausal women.Jul 01, 2003

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Pubmed Data : Am J Clin Nutr. 2003 Jul;78(1):123-30. PMID: 12816781

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Acta Pol Pharm. 2014 Mar-Apr;71(2):323-7. PMID: 25272653

Article Published Date : Feb 28, 2014

Study Type : Human Study

Additional Links

Substances : Soy

Diseases : Depression, Depression: Postmenopausal

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Natural Substance/Drug Synergy

Problem Substances : Fluoxetine (trade name Prozac) , Sertraline

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The administration of soybean could enhance the response to SSRI anti depressants in menopausal women.Feb 28, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Acta Pol Pharm. 2014 Mar-Apr;71(2):323-7. PMID: 25272653

Article Published Date : Feb 28, 2014

Study Type : Human Study

Additional Links

Substances : Soy

Diseases : Depression, Depression: Postmenopausal

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Natural Substance/Drug Synergy

Problem Substances : Fluoxetine (trade name Prozac) , Sertraline

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The consumption of antioxidants, e.g. soy products, tea, fruits and vegetables, reduces the risk for cerebral aneurysm. May 01, 2007

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Pubmed Data : Ann Epidemiol. 2007 May;17(5):359-63 PMID: 17462545

Article Published Date : May 01, 2007

Study Type : Human Study

Additional Links

Substances : Fruit: All, Green Tea, Soy, Vegetables: All

Diseases : Aneurysm: Cerebral, Cerebral Aneurysm

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The consumption of cured meat is correlated with higher rates of childhood acute leukemia, whereas the consumption of vegetables and bean-curd food lowers risk. Jan 13, 2009

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Pubmed Data : BMC Cancer. 2009 Jan 13;9:15 PMID: 19144145

Article Published Date : Jan 13, 2009

Study Type : Human Study

Additional Links

Substances : Beans: All , Soy, Vegetables: All

Diseases : Acute lymphoblastic leukemia (ALL), Acute Myeloid Leukemia

Pharmacological Actions : Chemopreventive

Additional Keywords : Childhood Leukemia

[+]

The consumption of shallot, garlic, soy food and green tea consumption protects against the risk of multiple myeloma. Jun 04, 2012

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Pubmed Data : Cancer Epidemiol. 2012 Jun 4. Epub 2012 Jun 4. PMID: 22673750

Article Published Date : Jun 04, 2012

Study Type : Human Study

Additional Links

Substances : Garlic, Green Tea, Shallot, Soy

Diseases : Multiple Myeloma: Prevention

[+]

These results suggest that combined administration of black soybean with fenofibrate enhances the antihyperlipidemic action of fenofibrate.Jun 01, 2015

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Pubmed Data : J Med Food. 2015 Jun ;18(6):615-8. Epub 2015 Feb 4. PMID: 25651043

Article Published Date : Jun 01, 2015

Study Type : Human Study

Additional Links

Substances : Polyphenols, Soy

Diseases : Diabetes Mellitus: Type 2, Hyperlipidemia

Additional Keywords : Drug Synergy, Phytotherapy, Plant Extracts

[+]

This study clarified the association between habitual miso consumption and good glycemic control, including glycemic variability in females.Apr 27, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Invest Dermatol. 2003 May ;120(5):835-41. PMID: 12713590

Article Published Date : May 01, 2003

Study Type : Human Study

Additional Links

Substances : Genistein, NAC (N-acetyl-L-cysteine)

Diseases : Aging

Pharmacological Actions : Antioxidants

[+]

Vaginally administered genistein and hyaluronic acid both improve symptoms of vaginal atrophy in postmenopausal women.May 31, 2011

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Pubmed Data : Arch Gynecol Obstet. 2011 Jun ;283(6):1319-23. Epub 2010 Jun 25. PMID: 20577750

Pubmed Data : Hum Exp Toxicol. 2011 Dec ;30(12):1931-44. Epub 2011 Mar 15. PMID: 21406484

Article Published Date : Nov 30, 2011

Study Type : Human In Vitro

Additional Links

Substances : Chrysanthemum Indicum, Soy

Diseases : Chemotherapy-Induced Toxicity: Cisplatin

Pharmacological Actions : Chemoprotective Agents, Renoprotective

Additional Keywords : Plant Extracts

[+]

The combination of centchroman with genistein has selective cytotoxic effect for human breast cancer cell lines.Oct 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Indian J Pharmacol. 2016 Nov-Dec;48(6):637-642. PMID: 28066099

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Pubmed Data : Pediatrics. 2012 Sep ;130(3):e699-702. Epub 2012 Aug 20. PMID: 22908106

Article Published Date : Aug 31, 2012

Study Type : Human: Case Report

Additional Links

Substances : Soy

Diseases : Congenital Hypothyroidism

Problem Substances : Soy

Adverse Pharmacological Actions : Endocrine Disruptor: Thyroid

[+]

Dietary genistein supplementation protects against lipopolysaccharide-induced intestinal injury through altering transcriptomic profile.Jun 30, 2020

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Pubmed Data : J Med Food. 2008 Sep;11(3):539-43. PMID: 18800904

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Pubmed Data : Vascul Pharmacol. 2008 Jul;49(1):1-5. Epub 2008 Mar 27. PMID: 18468493

Article Published Date : Jul 01, 2008

Study Type : Animal Study

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Substances : Genistein

Diseases : Diabetes: Cardiovascular Illness

Pharmacological Actions : Cardioprotective, Enzyme Inhibitors

[+]

Coffee contains the isoflavones genistein, daidzein and formononetin.Mar 10, 2010

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Pubmed Data : J Agric Food Chem. 2010 Mar 10;58(5):3002-7. PMID: 20131840

Article Published Date : Mar 10, 2010

Study Type : Animal Study

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Substances : Coffee, Daidzein, Genistein, Isoflavones

Additional Keywords : Substances that are Linked

[+]

Cytoprotective effect of genistein against dexamethasone-induced pancreatic β-cell apoptosis.Jul 27, 2022

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Pubmed Data : Sci Rep. 2022 Jul 28 ;12(1):12950. Epub 2022 Jul 28. PMID: 35902739

Article Published Date : Jul 27, 2022

Study Type : Animal Study

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Substances : Genistein

Diseases : Inflammation

Pharmacological Actions : Anti-Apoptotic, Bcl-2 protein down-regulation, Cytoprotective, NF-kappaB Inhibitor, Pancreato Protective Agents

Problem Substances : Dexamethasone

[+]

Dark soy sauce has a protective effect against acrylamide-induced neurotoxicity in rats by antioxidative activity.Jun 01, 2009

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Pubmed Data : Toxicol Mech Methods. 2009 Jun;19(5):369-74. PMID: 19778214

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Pubmed Data : Life Sci. 2003 Jul 25;73(10):1289-98. PMID: 12850244

Article Published Date : Jul 25, 2003

Study Type : Animal Study

Additional Links

Substances : Nattokinase, Soy

Diseases : Arteriosclerosis, Intima Media Thickening

[+]

Dietary supplementation with 180-day fermented dietary miso could act as a chemopreventive agent for colon carcinogenesis.Dec 01, 2005

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Pubmed Data : Oncol Rep. 2005 Dec;14(6):1559-64. PMID: 16273256

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Pubmed Data : Oxid Med Cell Longev. 2022 ;2022:1560435. Epub 2022 May 17. PMID: 35620577

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Pubmed Data : Int J Mol Sci. 2017 Feb 10 ;18(2). Epub 2017 Feb 10. PMID: 28208647

Article Published Date : Feb 09, 2017

Study Type : Animal Study

Additional Links

Substances : Soy

Diseases : Atherosclerosis

Pharmacological Actions : Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Fermented barley and soybean alleviated the severity of colitis in a DSS-induced colitis mouse model.Dec 02, 2016

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Pubmed Data : BMC Complement Altern Med. 2016 Dec 3 ;16(1):498. Epub 2016 Dec 3. PMID: 27912750

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Pubmed Data : Int J Reprod Biomed (Yazd). 2016 Feb ;14(2):95-102. PMID: 27200423

Article Published Date : Jan 31, 2016

Study Type : Animal Study

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Substances : Genistein

Diseases : Infertility: Male

Pharmacological Actions : Spermatogenic

Problem Substances : Morphine

[+]

Genistein administration might improve liver damages induced by morphine in mice.Jul 04, 2018

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Pubmed Data : Chin Med J (Engl). 2018 Jul 5 ;131(13):1598-1604. PMID: 29941714

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Pubmed Data : Oncotarget. 2017 Sep 22 ;8(37):61385-61392. Epub 2017 May 26. PMID: 28977871

Article Published Date : Sep 21, 2017

Study Type : Animal Study, In Vitro Study

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Substances : Genistein

Diseases : Gastrointestinal Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Gastroprotective, NF-kappaB Inhibitor

[+]

Genistein alleviates high-fat diet-induced obesity.Apr 07, 2022

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Pubmed Data : Nutrients. 2022 Apr 8 ;14(8). Epub 2022 Apr 8. PMID: 35458112

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Pubmed Data : Neurobiol Learn Mem. 2011 Mar;95(3):270-6. Epub 2010 Dec 7. PMID: 21144907

Article Published Date : Mar 01, 2011

Study Type : Animal Study

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Substances : Genistein

Diseases : Alzheimer's Disease, Learning disorders, Memory Impairment: Hormone Deficiency Induced

Pharmacological Actions : Neuroprotective Agents

[+]

Genistein ameliorates non-alcoholic fatty liver disease by targeting the thromboxane A2 pathway.May 30, 2018

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Pubmed Data : J Agric Food Chem. 2018 May 31. Epub 2018 May 31. PMID: 29771124

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Pubmed Data : Neurotox Res. 2020 Jul 1. Epub 2020 Jul 1. PMID: 32613603

Article Published Date : Jun 30, 2020

Study Type : Animal Study, In Vitro Study

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Substances : Genistein

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Genistein and moderate intensity exercise were effective in reducing the severity of NASH.May 31, 2020

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Pubmed Data : BMC Complement Med Ther. 2020 Jun 1 ;20(1):162. Epub 2020 Jun 1. PMID: 32482167

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Pubmed Data : Eur J Pharmacol. 2010 Dec 15;649(1-3):242-8. Epub 2010 Sep 18. PMID: 20854807

Article Published Date : Dec 15, 2010

Study Type : Animal Study

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Substances : Genistein

Diseases : Pulmonary Hypertension

Pharmacological Actions : Nitric Oxide Enhancer

[+]

Genistein attenuates renal ischemia-reperfusion injury.Dec 31, 2022

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Pubmed Data : Hum Exp Toxicol. 2023 ;42:9603271231164913. PMID: 36932924

Article Published Date : Dec 31, 2022

Study Type : Animal Study

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Substances : Genistein

Diseases : Ischemia, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Renoprotective

[+]

Genistein diet improves body weight, serum glucose and triglyceride levels.Dec 31, 2018

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Pubmed Data : Diabetes Metab Syndr Obes. 2019 ;12:2011-2021. Epub 2019 Oct 3. PMID: 31686880

Pubmed Data : Urology. 2004 Aug;64(2):389-93. PMID: 15302513

Article Published Date : Aug 01, 2004

Study Type : Animal Study

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Substances : Genistein

Diseases : Kidney Cancer

[+]

Genistein Inhibits Clostridioides difficile Infection.Mar 27, 2023

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Pubmed Data : J Infect Dis. 2023 Mar 28 ;227(6):806-819. PMID: 36628948

Article Published Date : Mar 27, 2023

Study Type : Animal Study

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Substances : Genistein

Diseases : Clostridium Infections

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents

[+]

Genistein inhibits high fat diet-induced obesity through miR-222 by targeting BTG2 and adipor1.Feb 29, 2020

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Pubmed Data : Food Funct. 2020 Mar 1 ;11(3):2418-2426. Epub 2020 Mar 4. PMID: 32129363

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Pubmed Data : Shock. 2019 Oct 15. Epub 2019 Oct 15. PMID: 31626039

Article Published Date : Oct 14, 2019

Study Type : Animal Study

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Substances : Genistein

Diseases : Burns

Pharmacological Actions : Antioxidants, Cardioprotective

[+]

Genistein protects against hyperglycemia and fatty liver disease in diet-induced prediabetes.Dec 31, 2021

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Pubmed Data : Neurotoxicology. 2016 Mar ;53:153-164. Epub 2016 Jan 18. PMID: 26797587

Article Published Date : Feb 29, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Genistein

Diseases : Lead Poisoning, Neurodegenerative Diseases

Pharmacological Actions : Antioxidants, Neuroprotective Agents, Superoxide Dismutase Up-regulation

Problem Substances : Lead

[+]

Genistein reduces hyperglycemia and pancreatic islet cell loss in a rat model of diabetic pancreatic damage.Feb 01, 2007

Genistein supplementation might be a potential therapeutic line for the management and prevention of diabetes-associated OCD.Mar 20, 2018

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Pubmed Data : J Basic Clin Physiol Pharmacol. 2018 Mar 21. Epub 2018 Mar 21. PMID: 29561730

Article Published Date : Mar 20, 2018

Study Type : Animal Study

Additional Links

Substances : Genistein

Diseases : Diabetic Complications, Obsessive-Compulsive Disorder

Pharmacological Actions : Neuroprotective Agents

[+]

Genistein suppresses the inflammation and GSK-3 pathway in an animal model of spontaneous ovarian cancer.Feb 07, 2021

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Pubmed Data : Oxid Med Cell Longev. 2020 ;2020:4569268. Epub 2020 May 27. PMID: 32566080

Article Published Date : Dec 31, 2019

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Pubmed Data : Nutrients. 2022 Apr 29 ;14(9). Epub 2022 Apr 29. PMID: 35565830

Article Published Date : Apr 28, 2022

Study Type : Animal Study

Additional Links

Substances : Genistein

Diseases : Muscle Atrophy

Pharmacological Actions : MicroRNA modulator

Problem Substances : Dexamethasone

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View the Evidence: 614 Abstracts with Soy Research

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"Soy intake is associated with lower lung cancer risk." Dec 01, 2011

Exposure to isoflavone-containing soy products may improve endothelial function. Aug 14, 2010

Genistein significantly improves glucose control and insulin sensitivity in postmenopausal women.Feb 28, 2017

Safety Study: There is little evidence that in those with normal thyroid function soy has any adverse effects. In those with hypothyroidism adequate iodine should be consumed to counterbalance the soy consumption.Mar 01, 2006

A combination of selenium, vitamin E and soy isoflavones reduces PSA levels and ower risk of prostate cancer in men with high-grade intraepithelial neoplasia. Jun 01, 2007

A combination of soy, isoflavones, lycopene, silymarin and antoxidants significantly increases PSA doubling time in men with prostate cancer. Dec 01, 2005

A daily supplement of soy protein prevents the increase in subcutaneous and total abdominal fat in postmenopausal women. Dec 01, 2007

A diet high in plant sterols, soy protein, viscous fibers and almonds compares favorably to statin therapy in reducing C-reactive protein. Jul 01, 2005

A diet high in soy products may be protective against the development of subarachnoid hemorrhage.Apr 01, 2006

A dietary pattern characterized by high intakes of vegetables, fruit, soy products, and fish, is significantly and inversely related to circulating high-sensitivity C-reactive protein. May 01, 2008

A high intake of some fruits, vegetables, and soybeans may be associated with a reduced breast cancer risk.Mar 01, 2007

A high intake of soy and isoflavones may be associated with a reduced prevalence of allergic rhinitis.Jun 01, 2005

A higher intake of soy foods and soy isoflavones is associated with lower sperm concentration.Nov 01, 2008

A low glycemic index diet with soy protein and phytosterols improves risk factors for cardiovascular disease in postmenopausal women.Feb 01, 2006

A moisturizer containing compounds found within soy is safe and effective in preventing photoaging. Sep 01, 2007

A multi-nutrient mixture of soy extract, fish protein polysaccharides, extracts from white tea, grape seed and tomato, vitamins C and E as well as zinc and chamomile extract improves signs of skin aging in post-menopausal women. Oct 01, 2006

A soy rich diet may prevent the vaginal atrophy in postmenopause. Jan 01, 2008

A vegetable-fruit-soy dietary pattern protects against breast cancer among postmenopausal Singapore Chinese women.Feb 24, 2010

Among women with breast cancer, soy food consumption was significantly associated with decreased risk of death and recurrence.Dec 09, 2009

An increased intake of some fruits, vegetables, and soy foods may be associated with breast cancer risk reduction in Korean women.Jan 01, 2007

Avocado/soybean unsaponifiables appear to have a preventive effect on joint space loss in osteoarthritis of the hip.Feb 01, 2002

Avocado/soybean unsaponifiables are safe and effective in the treatment of symptomatic osteoarthritis of the knee and hip.Dec 01, 1997

Consumption of legumes, soybeans in particular, was inversely associated with the risk type 2 diabetes. Jan 01, 2008

Consumption of soy foods may be associated with a reduction in colorectal cancer risk in women. Jan 01, 2010

Dietary intake of isoflavone is inversely associated with the risk of lower urinary tract symptoms. Dec 01, 2007

Dietary soy supplementation constitutes an effective alternative therapy for somatic and urogenital symptoms of the menopause.Nov 01, 2010

Early-life soy exposure is associated with early onset menarche.Mar 01, 2012

Effectiveness of genistein supplementation on metabolic factors and antioxidant Status in postmenopausal women with type 2 diabetes mellitus.Sep 30, 2019

Effects of genistein aglycone in glucocorticoid induced osteoporosis.Jun 30, 2023

Fermented soy therapy may have therapeutic value in treating platinum-resistant ovarian cancer. Jan 01, 2006

Fermented soymilk beneficially modifies the gut microbiota in premenopausal healthy women.Feb 26, 2018

Frequent miso soup and isoflavone consumption is associated with a reduced risk of breast cancer in Japanese women. Jun 18, 2003

Genistein and daidzein consumption are associated with a lower risk of prostate cancer. Aug 01, 2009

Genistein and puerarin could inhibit the pathway of NF-kappaB and TNF-alpha in asthma patients.Jan 31, 2010

Genistein appears to have a positive effect on hot flushes without a negative impact on endometrial thickness in early postmenopausal women.Jul 01, 2004

Genistein can reduce insulin resistance, oxidative and inflammatory indices along with improvement in fat metabolism in patients with NAFLD.May 31, 2017

Genistein compares favorably to HRT in supporting bone health in early postmenopausal women.Oct 01, 2002

Genistein has a positive effect on bone metabolism in osteopenic postmenopausal women, without increasing endometrial thickness. Jun 19, 2007

Genistein has favorable effects on some predictors of cardiovascular risk in osteopenic, postmenopausal women.Jan 18, 2010

Genistein has therapeutic value in reducing PSA levels in men with prostate cancer. Feb 01, 2004

Genistein induces long-term expression of progesterone receptor regardless of estrogen receptor status and improves the prognosis of endometrial cancer patients.Jun 17, 2022

Genistein inhibits nonalcoholic fatty liver disease.Nov 01, 2007

Genistein is safe and effective in improving bone density without adverse responses in breast density or endometrium thickness in osteopenic, postmenopausal women. Dec 01, 2008

Genistein may block metastasis and mortality in prostate cancer through blocking the activation of MEK4 and MMP-2 expression. Aug 19, 2009

Genistein reduces vasomotor symptoms, e.g. hot flush, within postmenopausal women.Jul 01, 2007

Genistein significantly decreases hot flash symptoms in healthy postmenopausal women.Feb 01, 2011

Genistein stimulates insulin sensitivity through gut microbiota reshaping and skeletal muscle AMPK activation in obese subjects. Dec 31, 2019

Habitual miso consumption is associated with a low prevalence of sarcopenia in patients with type 2 diabetes.Dec 27, 2020

High dietary intake of soy isoflavones was associated with lower risk of recurrence among post-menopausal patients with breast cancer positive for estrogen and progesterone receptor and those who were receiving anastrozole (Arimidex) as endocrine therapy.Feb 01, 2010

Higher concentrations of circulating genistein may reduce the risk of prostate cancer.Jun 02, 2009

Impact of isoflavone genistein on psoriasis in in vivo and in vitro investigations.Jan 13, 2021

Increased consumption of genistein is associated with better lung function in patients with asthma. Jan 01, 2004

Increasing dietary consumption of tomato based foods may beneficially increase serum adiponectin concentrations among postmenopausal women at increased breast cancer risk.Jan 31, 2014

Increasing soy consumption is associated with a decreased risk of COPD and breathlessness.Jan 01, 2009

Intake of miso soup was associated with lower epigastric symptoms.Dec 31, 2017

Isoflavone intake was associated with a decreased risk of lung cancer. Jan 13, 2010

Isoflavone-rich soy protein suppresses androgen receptor expression in men at high risk of prostate cancer. Jul 01, 2007

Japanese soy sauce fermentation degrades wheat allergen as determined by children with wheat allergy.Jun 01, 2004

Liquorice and soy sauce has been reported a life-saving concoction in a patient with Addison's disease.Jun 30, 2007

Long-term intake of miso soup decreases nighttime blood pressure in subjects with high-normal blood pressure or stage I hypertension.Aug 01, 2019

Lycopene and soy isoflavones have activity in prostate cancer patients with PSA relapse disease and may delay progression of both hormone-refractory and hormone-sensitive prostate cancer.Jul 01, 2009

Miso soup consumption enhances the bioavailability of the reduced form of supplemental coenzyme Q10.Dec 31, 2019

Mortality from Lung Cancer, Breast Cancer and Ischemic Heart Disease is inversely associated with soy consumption. Jul 01, 2006

Mycoprotein and tofu have satiating properties that persist for several hours after a meal.Jan 01, 2006

Oral intake of soy isoflavone aglycone improves the aged skin of adult women.Feb 01, 2007

Regular soy food intake may be associated with a reduced risk of breast cancer, and this effect is more pronounced in premenopausal women.Jan 01, 2008

Resveratrol and genistein may be potential drugs candidates for use in the treatment of COPD.Mar 27, 2016

Safety Study: dietary soy consumption during early pregnancy is not associated with the development of thyroid dysfunction or autoimmunity.Aug 25, 2001

Safety Study: soybean isoflavone exposure does not have feminizing effects on men. May 01, 2010

Safety: soy food consumption lowers estrogen levels in nipple aspirate fluid and serum. Jul 08, 2011

Soy and isoflavone intake may decrease the likelihood of periodontal disease.Jan 01, 2008

View the Evidence:
614 Abstracts with Soy Research