Soy: Fermented

Name	AC	CK
Osteoporosis	5	50
Diabetes Mellitus: Type 2	3	21
Hypertension	3	21
Addison's Disease	1	10
Breast Cancer	1	10
Gastroesophageal Reflux	1	10
Gluten Sensitivity	1	10
Heart Rate Variability: Increased	1	10
Osteopenia	1	10
Sarcopenia	1	10
Colon Cancer	2	4
Acrylamide-induced toxicity	1	2
Arteriosclerosis	1	2
Chemically-Induced Liver Damage	1	2
Cholesterol: High	1	2
Inflammation	1	2
Intima Media Thickening	1	2
Nerve Injuries	1	2
Neurotoxicity	1	2
Oxidative Stress	2	2
Peripheral Nerve Diseases	1	2
Sciatica	1	2
Thrombosis	2	2
Triglycerides: Elevated	1	2
Advanced Glycation End products (AGE)	1	1
Aging Skin	1	1
Bone Fractures	1	1
Coronavirus Infection	1	1
Diabetes: Glycation/A1C	1	1
Insulin Resistance	1	1
Metabolic Syndrome X	1	1

Name	AC	CK
Chemopreventive	3	14
Antihypertensive Agents	2	11
Hypoglycemic Agents	2	11
Gastroprotective	1	10
Secretagogue	1	10
Antioxidants	3	4
Neuroprotective Agents	2	4
Fibrinolytic Agents	2	3
Anti-Inflammatory Agents	1	2
Antiproliferative	1	2
Cyclooxygenase Inhibitors	1	2
Hepatoprotective	1	2
NF-kappaB Inhibitor	1	2
Neuritogenic	1	2
Nitric Oxide Inhibitor	1	2
Tumor Necrosis Factor (TNF) Alpha Inhibitor	1	2
Vascular Cell Adhesion Molecule-1 Inhibitor	1	2
Anti-Platelet	1	1
Anti-thrombotic	1	1
Antiviral Agents	1	1
Glucagon Like peptide 1 (GLP-1) Up-regulation	1	1
Insulinotrophic	1	1

[+]

Effect of fermented soymilk-honey from different probiotics on osteocalcin level in menopausal women.Oct 12, 2021

Click here to read the entire abstract

Pubmed Data : Nutrients. 2021 Oct 13 ;13(10). Epub 2021 Oct 13. PMID: 34684581

Article Published Date : Oct 12, 2021

Study Type : Human Study

Additional Links

Substances : Honey, Lactobacillus casei, Lactobacillus plantarum, Soy: Fermented

Diseases : Osteoporosis

Pharmacological Actions : Osteoprotective

[+]

Frequent miso soup and isoflavone consumption is associated with a reduced risk of breast cancer in Japanese women. Jun 18, 2003

Click here to read the entire abstract

Pubmed Data : J Natl Cancer Inst. 2003 Jun 18;95(12):906-13. PMID: 12813174

Article Published Date : Jun 18, 2003

Study Type : Human Study

Additional Links

Substances : Fermented Foods and Beverages, Isoflavones, Miso , Soy

Diseases : Breast Cancer

Pharmacological Actions : Chemopreventive

Additional Keywords : Risk Reduction

[+]

Habitual miso consumption is associated with a low prevalence of sarcopenia in patients with type 2 diabetes.Dec 27, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2020 Dec 28 ;13(1). Epub 2020 Dec 28. PMID: 33379405

Article Published Date : Dec 27, 2020

Study Type : Human Study

Additional Links

Substances : Miso

Diseases : Diabetes Mellitus: Type 2, Sarcopenia

Additional Keywords : Risk Reduction

[+]

Intake of fermented soybean (natto) increases circulating vitamin K2 and osteocalcin (a marker for bone formation) in normal individuals. Jan 01, 2000

Click here to read the entire abstract

Pubmed Data : J Bone Miner Metab. 2000;18(4):216-22. PMID: 10874601

Article Published Date : Jan 01, 2000

Study Type : Human Study

Additional Links

Substances : Natto , Vitamin K

Diseases : Osteoporosis

Pharmacological Actions : Secretagogue

[+]

Intake of miso soup was associated with lower epigastric symptoms.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2018 ;64(5):367-373. PMID: 30381627

Article Published Date : Dec 31, 2017

Study Type : Human Study

Additional Links

Substances : Miso , Soup

Diseases : Gastroesophageal Reflux

Pharmacological Actions : Gastroprotective

[+]

Japanese soy sauce fermentation degrades wheat allergen as determined by children with wheat allergy.Jun 01, 2004

Click here to read the entire abstract

Pubmed Data : Int J Mol Med. 2004 Jun;13(6):821-7. PMID: 15138619

Article Published Date : Jun 01, 2004

Study Type : Human Study

Additional Links

Substances : Fermented Foods and Beverages, Soy, Soy Sauce

Diseases : Gluten Sensitivity

[+]

Liquorice and soy sauce has been reported a life-saving concoction in a patient with Addison's disease.Jun 30, 2007

Click here to read the entire abstract

Pubmed Data : Ann Clin Biochem. 2007 Jul ;44(Pt 4):397-9. PMID: 17594790

Article Published Date : Jun 30, 2007

Study Type : Human Study

Additional Links

Substances : Glycyrrhizin, Soy Sauce

Diseases : Addison's Disease

[+]

Long-term intake of miso soup decreases nighttime blood pressure in subjects with high-normal blood pressure or stage I hypertension.Aug 01, 2019

Click here to read the entire abstract

Pubmed Data : Hypertens Res. 2019 Aug 2. Epub 2019 Aug 2. PMID: 31371810

Article Published Date : Aug 01, 2019

Study Type : Human Study

Additional Links

Substances : Miso , Soup

Diseases : Hypertension

Pharmacological Actions : Antihypertensive Agents

[+]

Miso soup consumption enhances the bioavailability of the reduced form of supplemental coenzyme Q10.Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Nutr Metab. 2020 ;2020:5349086. Epub 2020 Jan 7. PMID: 31998536

Article Published Date : Dec 31, 2019

Study Type : Human Study

Additional Links

Substances : Coenzyme Q10, Miso , Soup

Additional Keywords : Increased Bioavailability

[+]

Natto, a rich source of vitamin K2, promotes bone formation in premenopausal women. Apr 01, 2004

Click here to read the entire abstract

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2004 Apr;50(2):114-20. PMID: 15242015

Article Published Date : Apr 01, 2004

Study Type : Human Study

Additional Links

Substances : Natto , Vitamin K

Diseases : Osteoporosis

[+]

Prolonged intake of fermented soybean (natto) diets containing vitamin K2 (menaquinone-7) prevents bone loss in ovariectomized rats.Jan 01, 2000

Click here to read the entire abstract

Pubmed Data : J Bone Miner Metab. 2000;18(2):71-6. PMID: 10701161

Article Published Date : Jan 01, 2000

Study Type : Human Study

Additional Links

Substances : Natto , Vitamin K

Diseases : Osteopenia, Osteoporosis

[+]

The consumption of vitamin K2 rich fermented soybean food products may contribute to the relatively lower fracture risk of Japanese women. Apr 01, 2001

Click here to read the entire abstract

Pubmed Data : Nutrition. 2001 Apr;17(4):315-21. PMID: 11369171

Article Published Date : Apr 01, 2001

Study Type : Human Study

Additional Links

Substances : Fermented Foods and Beverages, Natto , Soy, Vitamin K, Vitamin K2: Menaquinone-7

Diseases : Osteoporosis

Additional Keywords : Risk Reduction

[+]

These results indicate that miso soup consumption might decrease the heart rate.Dec 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Intern Med. 2017;56(1):23-29. Epub 2017 Jan 1. PMID: 28049996

Article Published Date : Dec 31, 2016

Study Type : Human Study

Additional Links

Substances : Miso , Soup

Diseases : Heart Rate Variability: Increased, Hypertension

[+]

This study clarified the association between habitual miso consumption and good glycemic control, including glycemic variability in females.Apr 27, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2021 Apr 28 ;13(5). Epub 2021 Apr 28. PMID: 33924846

Article Published Date : Apr 27, 2021

Study Type : Human Study

Additional Links

Substances : Miso

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Hypoglycemic Agents

[+]

Usual dietary intake of fermented soybeans (Natto) is associated with bone mineral density in premenopausal women.Jun 01, 2002

Click here to read the entire abstract

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2002 Jun;48(3):207-15. PMID: 12350079

Article Published Date : Jun 01, 2002

Study Type : Human Study

Additional Links

Substances : Natto

Diseases : Osteoporosis

[+]

A fermented soy product, Natto, contributes to the regeneration of nerve function following sciatic nerve crush injury. Aug 23, 2009

Click here to read the entire abstract

Pubmed Data : J Biomed Sci. 2009 Aug 23;16(1):75. PMID: 19698158

Article Published Date : Aug 23, 2009

Study Type : Animal Study

Additional Links

Substances : Fermented Foods and Beverages, Natto

Diseases : Nerve Injuries

Pharmacological Actions : Neuritogenic

Additional Keywords : Nerve Regeneration

[+]

Dark soy sauce has a protective effect against acrylamide-induced neurotoxicity in rats by antioxidative activity.Jun 01, 2009

Click here to read the entire abstract

Pubmed Data : Toxicol Mech Methods. 2009 Jun;19(5):369-74. PMID: 19778214

Article Published Date : Jun 01, 2009

Study Type : Animal Study

Additional Links

Substances : Soy, Soy Sauce

Diseases : Neurotoxicity

Pharmacological Actions : Antioxidants, Neuroprotective Agents

[+]

Dietary supplementation with 180-day fermented dietary miso could act as a chemopreventive agent for colon carcinogenesis.Dec 01, 2005

Click here to read the entire abstract

Pubmed Data : Oncol Rep. 2005 Dec;14(6):1559-64. PMID: 16273256

Article Published Date : Dec 01, 2005

Study Type : Animal Study

Additional Links

Substances : Fermented Foods and Beverages, Miso , Soy

Diseases : Colon Cancer

Pharmacological Actions : Antiproliferative , Chemopreventive

[+]

Dietary supplementation with fermented soybeans suppresses intimal thickening.Mar 01, 2003

Click here to read the entire abstract

Pubmed Data : Nutrition. 2003 Mar;19(3):261-4. PMID: 12620531

Article Published Date : Mar 01, 2003

Study Type : Animal Study

Additional Links

Substances : Natto , Nattokinase

Diseases : Arteriosclerosis, Intima Media Thickening

Pharmacological Actions : Fibrinolytic Agents

Additional Keywords : Thrombolytic

[+]

Fermented miso prevents the induction of colonic aberrant crypt foci associated with colon carcinogenesis. Feb 17, 2006

Click here to read the entire abstract

Pubmed Data : Biochem Biophys Res Commun. 2006 Feb 17;340(3):800-6. Epub 2005 Dec 20. PMID: 11748458

Article Published Date : Feb 17, 2006

Study Type : Animal Study

Additional Links

Substances : Fermented Foods and Beverages, Miso , Soy

Diseases : Colon Cancer

Pharmacological Actions : Chemopreventive

[+]

Fermented soybean has anti-inflammatory properties in the kidney of high-fat-fed rats.Jul 01, 1987

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 1987 Jul;20(2):85-106. PMID: 21332402

Article Published Date : Jul 01, 1987

Study Type : Animal Study

Additional Links

Substances : Fermented Foods and Beverages, Soy, Soy: Fermented

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase Inhibitors, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Vascular Cell Adhesion Molecule-1 Inhibitor

[+]

Miso prevents chemically-induced liver injury in mice. Aug 01, 2008

Click here to read the entire abstract

Pubmed Data : Biosci Biotechnol Biochem. 2008 Aug;72(8):2236-8. Epub 2008 Aug 7. PMID: 18685190

Article Published Date : Aug 01, 2008

Study Type : Animal Study

Additional Links

Substances : Fermented Foods and Beverages, Miso , Soy

Diseases : Chemically-Induced Liver Damage

Pharmacological Actions : Hepatoprotective

[+]

Soy sauce is a promising seasoning for the treatment of high cholesterol through food.Oct 01, 2008

Click here to read the entire abstract

Pubmed Data : Int J Mol Med. 2008 Oct;22(4):565-70. PMID: 18813866

Article Published Date : Oct 01, 2008

Study Type : Animal Study

Additional Links

Substances : Soy, Soy Sauce

Diseases : Cholesterol: High, Triglycerides: Elevated

[+]

Soy sauce reduces the neurotoxic effects of acrylamide in rats.May 01, 2003

Click here to read the entire abstract

Pubmed Data : Immunopharmacol Immunotoxicol. 2003 May;25(2):213-24. PMID: 19778245

Article Published Date : May 01, 2003

Study Type : Animal Study

Additional Links

Substances : Soy Sauce

Diseases : Acrylamide-induced toxicity

Pharmacological Actions : Neuroprotective Agents

[+]

The fermented soy product natto improves neurobehavioral deficits after sciatic nerve injury in rats. May 01, 2007

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2007 May;21(5):401-5. PMID: 19309538

Article Published Date : May 01, 2007

Study Type : Animal Study

Additional Links

Substances : Fermented Foods and Beverages, Natto

Diseases : Peripheral Nerve Diseases, Sciatica

Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

A fermented soybean (natto) and astragalus combination stimulates hyaluronic acid synthesis in human skin cells. Jul 17, 2009

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2009 Jul 17. PMID: 19619633

Article Published Date : Jul 17, 2009

Study Type : In Vitro Study

Additional Links

Substances : Astragalus, Fermented Foods and Beverages, Natto , Soy

Diseases : Aging Skin

[+]

Chicken jelly 'Nikogori' soup only and soup with the addition of soy sauce had the highest antioxidative capacity as part of the medicated diet, 'Yakuzen'.Jul 01, 2006

Click here to read the entire abstract

Pubmed Data : Int J Mol Med. 2006 Jul;18(1):107-11. PMID: 16786161

Article Published Date : Jul 01, 2006

Study Type : In Vitro Study

Additional Links

Substances : Chicken extract, Soy Sauce

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants

[+]

Isoflavonoids and peptides from meju, long-term fermented soybeans, increase insulin sensitivity and exert insulinotropic effects in vitro.Feb 01, 2011

Click here to read the entire abstract

Pubmed Data : Nutrition. 2011 Feb;27(2):244-52. Epub 2010 Jun 11. PMID: 20541368

Article Published Date : Feb 01, 2011

Study Type : In Vitro Study

Additional Links

Substances : Daidzein, Genistein, Isoflavones, Soy, Soy: Fermented

Diseases : Diabetes Mellitus: Type 2, Insulin Resistance, Metabolic Syndrome X

Pharmacological Actions : Glucagon Like peptide 1 (GLP-1) Up-regulation, Hypoglycemic Agents, Insulinotrophic

[+]

Natto contains a protein with both antithrombotic and fibrinolytic effects. Nov 01, 2005

Click here to read the entire abstract

Pubmed Data : J Pharmacol Sci. 2005 Nov;99(3):247-51. Epub 2005 Oct 27. PMID: 16258229

Article Published Date : Nov 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Fermented Foods and Beverages, Natto , Soy

Diseases : Thrombosis

Pharmacological Actions : Anti-thrombotic, Fibrinolytic Agents

[+]

Natto extract, a Japanese fermented soybean food, directly inhibits viral infections including SARS-CoV-2 in vitro.Jul 12, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biochem Biophys Res Commun. 2021 Jul 13 ;570:21-25. Epub 2021 Jul 13. PMID: 34271432

Article Published Date : Jul 12, 2021

Study Type : In Vitro Study

Additional Links

Substances : Natto

Diseases : Coronavirus Infection

Pharmacological Actions : Antiviral Agents

[+]

Nattokinase reduces red blood cell aggregation.Jan 01, 2006

Click here to read the entire abstract

Pubmed Data : Clin Hemorheol Microcirc. 2006;35(1-2):139-42. PMID: 16899918

Article Published Date : Jan 01, 2006

Study Type : In Vitro Study

Additional Links

Substances : Natto , Nattokinase

Diseases : Thrombosis

Pharmacological Actions : Anti-Platelet

[+]

Soy sauce has antioxidant and anti-glycation properties. Aug 23, 2011

Click here to read the entire abstract

Pubmed Data : J Med Food. 2011 Aug 23. Epub 2011 Aug 23. PMID: 21861728

Article Published Date : Aug 23, 2011

Study Type : In Vitro Study

Additional Links

Substances : Soy Sauce

Diseases : Advanced Glycation End products (AGE), Diabetes: Glycation/A1C, Oxidative Stress

Pharmacological Actions : Antioxidants

[+]

The ingredients of miso attenuate sympathetic nerve activity, resulting in lowered blood pressure and heart rate.Aug 30, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Environ Health Prev Med. 2020 Aug 31 ;25(1):45. Epub 2020 Aug 31. PMID: 32867671

Article Published Date : Aug 30, 2020

Study Type : Review

Additional Links

Substances : Miso

Diseases : Hypertension

Pharmacological Actions : Antihypertensive Agents

[+]

The intake of natto, an excellent source of vitamin K2, may reduce bone fracture risk. Sep 01, 2009

Click here to read the entire abstract

Pubmed Data : Clin Calcium. 2009 Sep;19(9):1362-9. PMID: 19721210

Article Published Date : Sep 01, 2009

Study Type : Review

Additional Links

Substances : Natto , Vitamin K2, Vitamin K2: Menaquinone-7

Diseases : Bone Fractures

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View the Evidence: 34 Abstracts with Soy: Fermented Research

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Effect of fermented soymilk-honey from different probiotics on osteocalcin level in menopausal women.Oct 12, 2021

Frequent miso soup and isoflavone consumption is associated with a reduced risk of breast cancer in Japanese women. Jun 18, 2003

Habitual miso consumption is associated with a low prevalence of sarcopenia in patients with type 2 diabetes.Dec 27, 2020

Intake of fermented soybean (natto) increases circulating vitamin K2 and osteocalcin (a marker for bone formation) in normal individuals. Jan 01, 2000

Intake of miso soup was associated with lower epigastric symptoms.Dec 31, 2017

Japanese soy sauce fermentation degrades wheat allergen as determined by children with wheat allergy.Jun 01, 2004

Liquorice and soy sauce has been reported a life-saving concoction in a patient with Addison's disease.Jun 30, 2007

Long-term intake of miso soup decreases nighttime blood pressure in subjects with high-normal blood pressure or stage I hypertension.Aug 01, 2019

Miso soup consumption enhances the bioavailability of the reduced form of supplemental coenzyme Q10.Dec 31, 2019

Natto, a rich source of vitamin K2, promotes bone formation in premenopausal women. Apr 01, 2004

Prolonged intake of fermented soybean (natto) diets containing vitamin K2 (menaquinone-7) prevents bone loss in ovariectomized rats.Jan 01, 2000

The consumption of vitamin K2 rich fermented soybean food products may contribute to the relatively lower fracture risk of Japanese women. Apr 01, 2001

These results indicate that miso soup consumption might decrease the heart rate.Dec 31, 2016

This study clarified the association between habitual miso consumption and good glycemic control, including glycemic variability in females.Apr 27, 2021

Usual dietary intake of fermented soybeans (Natto) is associated with bone mineral density in premenopausal women.Jun 01, 2002

A fermented soy product, Natto, contributes to the regeneration of nerve function following sciatic nerve crush injury. Aug 23, 2009

Dark soy sauce has a protective effect against acrylamide-induced neurotoxicity in rats by antioxidative activity.Jun 01, 2009

Dietary supplementation with 180-day fermented dietary miso could act as a chemopreventive agent for colon carcinogenesis.Dec 01, 2005

Dietary supplementation with fermented soybeans suppresses intimal thickening.Mar 01, 2003

Fermented miso prevents the induction of colonic aberrant crypt foci associated with colon carcinogenesis. Feb 17, 2006

Fermented soybean has anti-inflammatory properties in the kidney of high-fat-fed rats.Jul 01, 1987

Miso prevents chemically-induced liver injury in mice. Aug 01, 2008

Soy sauce is a promising seasoning for the treatment of high cholesterol through food.Oct 01, 2008

Soy sauce reduces the neurotoxic effects of acrylamide in rats.May 01, 2003

The fermented soy product natto improves neurobehavioral deficits after sciatic nerve injury in rats. May 01, 2007

A fermented soybean (natto) and astragalus combination stimulates hyaluronic acid synthesis in human skin cells. Jul 17, 2009

Chicken jelly 'Nikogori' soup only and soup with the addition of soy sauce had the highest antioxidative capacity as part of the medicated diet, 'Yakuzen'.Jul 01, 2006

Isoflavonoids and peptides from meju, long-term fermented soybeans, increase insulin sensitivity and exert insulinotropic effects in vitro.Feb 01, 2011

Natto contains a protein with both antithrombotic and fibrinolytic effects. Nov 01, 2005

Natto extract, a Japanese fermented soybean food, directly inhibits viral infections including SARS-CoV-2 in vitro.Jul 12, 2021

Nattokinase reduces red blood cell aggregation.Jan 01, 2006

Soy sauce has antioxidant and anti-glycation properties. Aug 23, 2011

The ingredients of miso attenuate sympathetic nerve activity, resulting in lowered blood pressure and heart rate.Aug 30, 2020

The intake of natto, an excellent source of vitamin K2, may reduce bone fracture risk. Sep 01, 2009

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Soy: Fermented

View the Evidence:
34 Abstracts with Soy: Fermented Research