Sweet Potato

Name	AC	CK
Inflammation	10	26
High Fat Diet	11	22
Hyperglycemia	7	21
Chemically-Induced Liver Damage	7	13
Oxidative Stress	8	13
Leukemia	2	12
Hyperuricemia	5	11
Colorectal Cancer	5	10
Constipation	1	10
Diabetes Mellitus: Type 2	6	10
Colitis	5	9
Alcohol Toxicity	4	7
Cardiovascular Diseases	4	7
Kidney Damage	3	7
Prostate Cancer	2	7
Aging	3	6
Alcoholic Liver Disease	3	6
Colon Cancer	6	6
Atherosclerosis	3	5
Obesity	3	5
Brain Inflammation	2	4
Cognitive Decline/Dysfunction	2	4
Colorectal Cancer: Prevention	2	4
Gastric Cancer	3	4
Gastric Ulcer	2	4
High Fructose Diet	2	4
Lipid Peroxidation	2	4
Lipopolysaccharide-Induced Toxicity	3	4
Stroke: Ischemic	2	4
Breast Cancer	3	3
Diabetic Retinopathy	2	3
Nonalcoholic fatty liver disease (NAFLD)	2	3
Alzheimer's Disease	1	2
Arthritis	1	2
Benzo[a]pyrene-induced Toxicity	1	2
Bisphenol Toxicity	1	2
Bladder Cancer	2	2
Chemotherapy-Induced Toxicity: Doxorubicin	1	2
Diabetes Mellitus: Type 2: Prevention	1	2
Diabetes: Oxidative Stress	1	2
Dry Eye Syndromes	1	2
Hepatic Steatosis	1	2
Hepatitis: Lectin-Induced (concanavalin)	1	2
High Sugar Diet	1	2
Hypertension	1	2
Immunologic Deficiency Syndromes	1	2
Inflammatory Bowel Diseases	1	2
Insulin Resistance	1	2
Klebsiella Infections	1	2
Lead Poisoning	1	2
Learning disorders	1	2
Liver Injury: Ischemia/reperfusion	1	2
Lung Cancer	2	2
Male Reproductive Development Abnormalities	1	2
Memory Disorders	1	2
Metabolic Syndrome X	1	2
Murine Leukemia Virus	1	2
Neurodegenerative Diseases	1	2
Sarcomas	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Thrombocytopenia	1	2
Ultraviolet Radiation Induced Damage	1	2
Acute lymphoblastic leukemia (ALL)	1	1
Cancer Metastasis	1	1
Dyslipidemias	1	1
Foodborne Pathogens: Prevention/Food Preservation	1	1
Galactosemias	1	1
Glioma	1	1
Head and Neck Cancer	1	1
Infant Nutrition: Infant Formula	1	1
Liver Cancer	1	1
Ovarian Cancer	1	1
Pseudomonas aeruginosa	1	1
Radiation Associated Toxicity: Cobalt-60	1	1
Retinal Diseases	1	1
Salmonella Infections	1	1
Staphylococcus aureus infection	1	1
Ulcerative Colitis	1	1

Name	AC	CK
Anti-Inflammatory Agents	32	58
Antioxidants	31	55
Hypoglycemic Agents	10	27
Hepatoprotective	13	24
Gastrointestinal Agents	9	23
Tumor Necrosis Factor (TNF) Alpha Inhibitor	11	18
Apoptotic	12	16
NF-kappaB Inhibitor	8	15
Renoprotective	7	15
Neuroprotective Agents	7	14
Antiproliferative	9	13
Interleukin-6 Downregulation	8	13
Chemopreventive	4	12
Interleukin-1 beta downregulation	5	10
Anti-Apoptotic	4	8
Antineoplastic Agents	3	8
Cardioprotective	3	6
Immunomodulatory	3	6
Malondialdehyde Down-regulation	3	6
Nitric Oxide Inhibitor	4	6
Gastroprotective	3	5
Hypolipidemic	3	5
Anti-Ulcer Agents	2	4
Anticarcinogenic Agents	1	4
Autophagy Up-regulation	2	4
Brain-derived neurotrophic factor modulator	2	4
Chemoprotective Agents	2	4
Cyclooxygenase 2 Inhibitors	2	4
Nrf2 activation	3	4
Superoxide Dismutase Up-regulation	2	4
Anti-atherogenic	2	3
Anti-metastatic	2	3
MicroRNA modulator	2	3
Anti-Bacterial Agents	1	2
Anticholesteremic Agents	1	2
Antihypertensive Agents	1	2
Catalase Up-Regulation	1	2
Cell cycle arrest	1	2
Heme oxygenase-1 up-regulation	2	2
Immunostimulatory	1	2
Interleukin-10 upregulation	1	2
Interleukin-17 downregulation	1	2
Pancreato Protective Agents	1	2
Phase II Detoxification Enzyme Inducer	1	2
Photoprotective	1	2
Postaglandin PGE2 downregulation	1	2
Uricosuric Agents	1	2
Antifungal Agents	1	1
Antimicrobial	1	1
Bcl-2 protein down-regulation	1	1
Cytotoxic	1	1
Interleukin-8 downregulation	1	1
Radioprotective	1	1

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Anthocyanin-rich extract from purple potatoes decreases postprandial glycemic response and affects inflammation markers in healthy men.Apr 24, 2020

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Pubmed Data : Food Chem. 2020 Apr 25 ;310:125797. Epub 2019 Oct 26. PMID: 31818516

An anthocyanin-rich purple sweet potato extract could be a safe and effective anti-hyperuricemia bioactive agent or functional food.Sep 01, 2015

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Pubmed Data : Food Funct. 2015 Sep 2 ;6(9):3045-55. PMID: 26201407

Article Published Date : Sep 01, 2015

Study Type : Animal Study

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Substances : Sweet Potato: Purple

Diseases : Hyperuricemia

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Plant Extracts

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Anthocyanin enriched sweet potatoes may protect against colorectal cancer by inducing cell-cycle arrest, antiproliferative, and apoptotic mechanisms.Oct 31, 2013

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Pubmed Data : Molecules. 2019 Aug 28 ;24(17). Epub 2019 Aug 28. PMID: 31466303

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Pubmed Data : Int J Mol Med. 2013 Dec ;32(6):1319-28. Epub 2013 Oct 11. PMID: 24127171

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Purple sweet potato anthocyanins normalize the blood glucose concentration and restore the gut microbiota in mice with type 2 diabetes mellitus.Jun 14, 2024

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Pubmed Data : Heliyon. 2024 Jun 15 ;10(11):e31784. Epub 2024 May 23. PMID: 38845993

Article Published Date : Jun 14, 2024

Study Type : Animal Study

Additional Links

Substances : Anthocyanins, Sweet Potato: Purple

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Antioxidants, Gastrointestinal Agents, Hypoglycemic Agents

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Purple sweet potato anthocyanins were able to attenuate chronic liver injury from carbon tetrachloride.Jun 30, 2014

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Pubmed Data : Cell Biochem Biophys. 2014 Jul ;69(3):539-48. PMID: 24442992

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Pubmed Data : J Nutr Biochem. 2018 Nov 12 ;65:35-45. Epub 2018 Nov 12. PMID: 30616064

Article Published Date : Nov 11, 2018

Study Type : Animal Study

Additional Links

Substances : Anthocyanins, Sweet Potato: Purple

Diseases : Cognitive Decline/Dysfunction, High Fat Diet

Pharmacological Actions : Neuroprotective Agents

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Purple sweet potato extract effects on levels of inflammatory markers and chondrocyte count in gout arthritis.Nov 30, 2023

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Pubmed Data : Foot Ankle Surg. 2023 Dec ;29(8):611-615. Epub 2023 Jul 20. PMID: 37953101

This is the first report to demonstrate the in vitro and in vivo anticancer activity of sweet potato greens in prostate cancer.Nov 30, 2011

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Pubmed Data : Carcinogenesis. 2011 Dec ;32(12):1872-80. Epub 2011 Sep 26. PMID: 21948980

Article Published Date : Nov 30, 2011

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Polyphenols, Sweet Potato

Diseases : Prostate Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

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This study proves the neuroprotective effect of purple sweet potato water extract.Mar 31, 2022

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Pubmed Data : Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2015 May ;40(5):499-503. PMID: 26032078

Article Published Date : Apr 30, 2015

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Pubmed Data : J Agric Food Chem. 2018 Sep 19 ;66(37):9704-9718. Epub 2018 Sep 10. PMID: 30160115

Article Published Date : Sep 18, 2018

Study Type : In Vitro Study

Additional Links

Substances : Sweet Potato

Diseases : Breast Cancer

Pharmacological Actions : Antiproliferative , MicroRNA modulator

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Anticancer effects of sweet potato protein on human colorectal cancer cells.Jun 06, 2013

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Purple-fleshed sweet potato extracts could induce apoptosis in MCF-7 and SNU-1 cancer cells through extrinsic and intrinsic pathway.Dec 31, 2014

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Pubmed Data : Food Res Int. 2020 11 ;137:109647. Epub 2020 Sep 1. PMID: 33233226

Article Published Date : Jan 10, 2020

Study Type : In Vitro Study

Additional Links

Substances : Sweet Potato: Purple

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Heme oxygenase-1 up-regulation, Nitric Oxide Inhibitor, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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These results indicated that purple sweet potato leaves could modulate adipose tissue mass and inflammation.Dec 31, 2014

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Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:126302. Epub 2015 Jun 11. PMID: 26170870

View the Evidence: 108 Abstracts with Sweet Potato Research

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Anthocyanin-rich extract from purple potatoes decreases postprandial glycemic response and affects inflammation markers in healthy men.Apr 24, 2020

Improvement of constipation in leukemia patients undergoing chemotherapy using sweet potato.Dec 31, 2015

Ameliorative effects of polyphenols from purple potato leaves on renal injury and associated inflammation induced by hyperuricemia.Dec 31, 2021

Purple sweet potato powder containing anthocyanin mitigates high-fat-diet-induced dry eye disease.Apr 09, 2023

A purple sweet potato extract rich in caffeoylquinic acids had a neuroprotective effect on mouse brain and could improve the spatial learning and memory.May 28, 2013

Alkali-soluble sweet potato polysaccharide can be developed as a novel anti-inflammation agent.Mar 19, 2019

Ameliorative effect of structurally divergent oleanane triterpenoid, 3-epifriedelinol from Ipomoea batatas against BPA-induced gonadotoxicity.Dec 28, 2022

An anthocyanin-rich purple sweet potato extract could be a safe and effective anti-hyperuricemia bioactive agent or functional food.Sep 01, 2015

Anthocyanin enriched sweet potatoes may protect against colorectal cancer by inducing cell-cycle arrest, antiproliferative, and apoptotic mechanisms.Oct 31, 2013

Anthocyanin Extract from Purple Sweet Potato Exacerbate Mitophagy to Ameliorate Pyroptosis in Klebsiella pneumoniae Infection.Oct 21, 2021

Anthocyanin extracts from purple sweet potato exerted strong antioxidant effects in vitro and also had anti-aging, anti-hyperglycemic, and anti-tumor activities.Sep 30, 2013

Anthocyanin from purple sweet potato attenuates lead-induced reproductive toxicity mediated by JNK signaling pathway in male mice.Aug 23, 2021

Anthocyanin from purple sweet potato could be developed as a functional food for treatment of diabetes.Dec 30, 2020

Anthocyanins derived from Balinese cultivar of purple sweet potato possesses antioxidant activity.Jan 14, 2019

Anthocyanins from purple sweet potato alleviate doxorubicin-induced cardiotoxicity in vitro and in vivo.Dec 31, 2020

Anthocyanins from purple sweet potato and purple potato are good source of anti inflammatory phytochemicals to prevent alcoholic liver disease.Mar 15, 2015

Anti-aging effects of the fermented anthocyanin extracts of purple sweet potato on Caenorhabditis elegans.Dec 12, 2021

Anti-atherosclerotic activity of aqueous extract of Ipomoea batatas (L.) leaves in high-fat diet-induced atherosclerosis.Jan 05, 2022

Anti-diabetic activity of aqueous extract of Ipomoea batatas L. in alloxan induced diabetic Wistar rats.Jun 30, 2018

Anti-inflammatory effects of purple sweet potato anthocyanin extract in DSS-induced colitis.Nov 14, 2021

Antidiabetic and antioxidative potential of the blue congo variety of purple potato extract.Aug 27, 2019

Curcuma longa L and purple sweet potato had a positive effect on immunomodulation in C57BL/6 mice induced by LP-BM5 leukemia retrovirus infection.Jun 30, 2018

Diacylated anthocyanins from purple sweet potato attenuate hyperglycemia and hyperuricemia.Apr 13, 2023

Diacylated anthocyanins from purple sweet potato attenuate hyperglycemia and hyperuricemia.Apr 14, 2023

Enhancement of the Antiobesity and Antioxidant Effect ofPurple sweet potato extracts and enhancement of the effects by fermentation.May 30, 2021

Gastroprotective effects of polysaccharides from purple sweet potato on an ethanol-induced gastric ulcerJun 16, 2024

Green sweet potato leaves increase Nrf2-mediated antioxidant activity and facilitate benzo[ a]pyrene metabolism in the liver.Jun 30, 2022

Highly acylated anthocyanins from purple sweet potato alleviate hyperuricemia and kidney inflammation.Jun 04, 2019

Immune-enhancing effects of a novel glucan from purple sweet potato Ipomoea batatas.Aug 17, 2021

Immune-enhancing effects of polysaccharides from purple sweet potato.Feb 14, 2019

Impact of purple sweet potato polysaccharides on the fecal metabolome in a murine colitis model.Apr 06, 2022

Inhibitory regulation of purple sweet potato polysaccharide on the hepatotoxicity of tri-(2,3-dibromopropyl) isocyanate.Nov 19, 2021

Ipomoea batatas L. Lam. ameliorates acute and chronic inflammation.Jul 12, 2018

Oral administration of probiotic-fermented purple sweet potato yogurt may attenuate cardiomyocyte apoptosis in spontaneously hypertensive rat hearts.Nov 30, 2013

Photoprotective effects of sweet potato leaf polyphenols and caffeic acid against UV-induced skin-damage.Jul 03, 2022

Protective effect of carotenoid extract from orange-fleshed sweet potato on gastric ulcer.Dec 16, 2021

Purple potato anthocyanins could be an effective therapeutic agent in alcohol-induced liver injuries by inhibiting CYP2E1 expression.Oct 18, 2015

Purple sweet potato anthocyanin attenuates fat-induced mortality in Drosophila melanogaster.Jun 17, 2016

Purple sweet potato anthocyanin attenuates high fat-induced neuroinflammation.Jan 16, 2018

Purple sweet potato anthocyanin can exert renal protection by inhibiting ROS in high fat diet. Dec 31, 2018

Purple sweet potato anthocyanins attenuates steatohepatitis induced by high fat diet combined with carbon tetrachloride.Jun 30, 2018

Purple sweet potato anthocyanins exhibited beneficial effects on hepatic steatosis.Jun 20, 2017

Purple sweet potato anthocyanins have preventive effect on acute and subacute alcoholic liver damage.Mar 18, 2014

Purple sweet potato anthocyanins normalize the blood glucose concentration and restore the gut microbiota in mice with type 2 diabetes mellitus.Jun 14, 2024

Purple sweet potato anthocyanins were able to attenuate chronic liver injury from carbon tetrachloride.Jun 30, 2014

Purple sweet potato color attenuated NLRP3 inflammasome by inducing autophagy to delay endothelial senescence.Dec 25, 2018

Purple sweet potato color protects against hepatocyte apoptosis through Sirt1 activation in high-fat-diet-treated mice.Dec 31, 2019

Purple sweet potato color protects against high-fat diet-induced cognitive deficits.Nov 11, 2018

Purple sweet potato extract effects on levels of inflammatory markers and chondrocyte count in gout arthritis.Nov 30, 2023

Purple Sweet Potato Extract extends lifespan by activating autophagy pathway in male Drosophila melanogaster.Jan 31, 2021

Purple sweet potato extract maintains intestinal homeostasis and extend lifespan through increasing autophagy in female Drosophila melanogaster.Jul 14, 2021

Purple sweet potato extract may ameliorate immune dysfunction due to LP-BM5 MuLV infection by modulating antioxidant defense systems.Jun 14, 2015

Purple sweet potato had beneficial effects against induced kidney dysfunction and damage from a high fat diet.Jun 30, 2014

Purple sweet potato induces antioxidant defense via the Nrf2 pathway and reduces inflammation via NF-κB inhibition in DMN-induced liver injury.Dec 31, 2010

Purple sweet potato may be useful for mitigating inflammatory brain diseases by the inhibition of proinflammatory molecule production.Jan 31, 2010

Purple sweet potato polysaccharide ameliorates concanavalin A-induced hepatic injury by inhibiting inflammation and oxidative stress.Jun 30, 2024

Purple sweet potato protected against HFD-induced hepatic inflammation by boosting NAD⁺ level to inhibit NLRP3 inflammasome activation.Aug 07, 2017

Purple sweet potato protected against high fat diet induced hepatic insulin resistance.May 31, 2013

Purple sweet potato total flavonoids can prevent CCl4-induced acute liver injury in mice.Oct 31, 2013

Purple-fleshed potato has the potential to aid in the amelioration of ulcerative colitis symptoms.Mar 07, 2021

Resistant starch from purple sweet potatoes alleviates dextran sulfate sodium-induced colitis.Mar 26, 2024

Shinzami extract and anthocyanins have a hepatoprotective effect on the liver damage induced by hepatic I/R by improving antioxidant status.Nov 25, 2014

Sweet potato-supplemented diets could reduce the adenoma number in the animals.Aug 31, 2017

The effect of anthocyanin-rich purple vegetable diets on metabolic syndrome in obese rats.Nov 30, 2017

The protective effect of sweet potato root tuber on chemotherapy-induced thrombocytopenia.Jun 16, 2022

The results of this study indicated a significant neuroprotective effect of anthocyanin derived from Balinese cultivar of purple sweet potato.Nov 24, 2018

The role of lutein-rich purple sweet potato leaf extract on the amelioration of diabetic retinopathy.Dec 31, 2022

These findings indicated that purple sweet potato colour could be a potential treatment to improve the cognitive impairment associated with obesity.Dec 31, 2018

These results of this study revealed antidiabetic effects of methanolic I. batatas L extract.Feb 28, 2018

This is the first report to demonstrate the in vitro and in vivo anticancer activity of sweet potato greens in prostate cancer.Nov 30, 2011

This study proves the neuroprotective effect of purple sweet potato water extract.Mar 31, 2022

White sweet potato ameliorates hyperglycemia and regenerates pancreatic islets in diabetic mice.Dec 13, 1901

Sweet Potato

View the Evidence:
108 Abstracts with Sweet Potato Research