Terminalia

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72 Diseases Researched for Terminalia
NameACCKFocus
Aging Skin211Locked
Diabetes Mellitus: Type 2510Locked
Dry Skin 110Locked
Heart Failure110Locked
Lipopolysaccharide-Induced Toxicity37Locked
Helicobacter Pylori Infection46Locked
Oxidative Stress36Locked
Breast Cancer35Locked
Gastric Ulcer35Locked
Chemotherapy-Induced Kidney Damage24Locked
Chemotherapy-Induced Toxicity: Cisplatin24Locked
Insulin Resistance24Locked
Nonalcoholic fatty liver disease (NAFLD)24Locked
Arthritis23Locked
Atopic Dermatitis13Locked
Endometritis13Locked
Inflammation23Locked
Acetaminophen (Tylenol) Toxicity 12Locked
Androgenic Alopecia12Locked
Candidiasis22Locked
Cardiac Hypertrophy12Locked
Cardiomegaly12Locked
Cardiomyopathy12Locked
Cerebral Ischemia12Locked
Chemically-Induced Liver Damage12Locked
Chemotherapy-Induced Toxicity: Doxorubicin12Locked
Colitis12Locked
Coronary Artery Disease12Locked
Cytomegalovirus Infections12Locked
Depression12Locked
Diarrhea12Locked
Fluoride Toxicity 12Locked
Gout12Locked
HSV-112Locked
Hypercholesterolemia12Locked
Hyperglycemia12Locked
Immunodeficiency: Common Variable12Locked
Ischemia: Myocardial12Locked
Kidney Damage: Chemically-Induced12Locked
Lipid Peroxidation12Locked
Liver Damage: Drug-Induced12Locked
Lung Damage12Locked
Malaria12Locked
Myocardial Fibrosis 12Locked
Myocardial Infarction12Locked
Polycystic Ovary Syndrome12Locked
Sepsis12Locked
Alzheimer's Disease11Locked
Bacillus Cereus infection11Locked
Breast Cancer: Triple Negative 11Locked
Cancers: All11Locked
Candida Albicans11Locked
Candida Infection 11Locked
Cholangiocarcinoma11Locked
Cholera11Locked
Cognitive Decline/Dysfunction11Locked
Colon Cancer11Locked
Colorectal Cancer11Locked
Coronavirus Disease (Covid-19)11Locked
Foodborne Pathogens: Prevention/Food Preservation11Locked
HIV Infections11Locked
Heavy Metal Toxicity11Locked
Hepatitis C11Locked
Influenza11Locked
Liver Cancer11Locked
Melanoma11Locked
Obesity11Locked
Osteoporosis11Locked
Staphylococcus aureus: Methicillin-resistant (MRSA)11Locked
Toxoplasma gondii Infection11Locked
Tuberculosis11Locked
Vibrio Infections11Locked
58 Pharmacological Actions Researched for Terminalia
NameACCKFocus
Antioxidants1322Locked
Anti-Inflammatory Agents919Locked
Immunomodulatory413Locked
Cardioprotective612Locked
Immunostimulatory212Locked
Anti-Bacterial Agents810Locked
Dermatologic Agents110Locked
Hypoglycemic Agents510Locked
Apoptotic68Locked
Hepatoprotective48Locked
Interleukin-1 beta downregulation38Locked
Interleukin-6 Downregulation38Locked
Antiviral Agents57Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor37Locked
Chemoprotective Agents36Locked
NF-kappaB Inhibitor26Locked
Renoprotective36Locked
Antiproliferative 55Locked
Interleukin-10 upregulation25Locked
Anti-Ulcer Agents24Locked
Antineoplastic Agents24Locked
Gastrointestinal Agents24Locked
Gastroprotective24Locked
Insulin Sensitizers24Locked
Neuroprotective Agents34Locked
Anti-metastatic33Locked
Antifungal Agents33Locked
Interleukin-8 downregulation13Locked
STAT3 Inhibitor13Locked
Transforming growth factor beta (TGF-β) inhibitor23Locked
Analgesics12Locked
Anti-Angiogenic12Locked
Anti-Apoptotic12Locked
Antidepressive Agents12Locked
Antidiarrheals12Locked
Antimalarials12Locked
Antinoceceptive 12Locked
Catalase Up-Regulation12Locked
Glutathione Upregulation 12Locked
Heat Shock Protein Inducer12Locked
Insulin-releasing12Locked
Interleukin-4 upregulation12Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor12Locked
SIRT1 Activator12Locked
Superoxide Dismutase Up-regulation12Locked
Vascular Endothelial Growth Factor Inhibitors12Locked
Xanthine oxidase inhibitor12Locked
Acetylcholinesterase Inhibitor11Locked
Anti-Adipogenic11Locked
Antimicrobial11Locked
Antiparasitic Agents11Locked
Chemopreventive11Locked
Cytoprotective11Locked
Food Preservatives11Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor11Locked
Neurominidase Inhibitor11Locked
Osteoprotective 11Locked
Reverse Transcriptase Inhibitors11Locked

View the Evidence:
76 Abstracts with Terminalia Research

[+]

A standardized combination of Terminalia chebula and Withania somnifera extracts enhances immune function in adults.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Nutr Res. 2024 ;68. Epub 2024 May 29. PMID: 38863743
Article Published Date : Dec 31, 2023
Study Type : Human Study
Additional Links
Substances : Ashwagandha, Terminalia
Pharmacological Actions : Immunomodulatory, Immunostimulatory
[+]

Pentacyclic triterpenes from Terminalia arjuna show multiple benefits on aged and dry skin.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Skin Pharmacol Physiol. 2014 ;27(2):71-81. Epub 2013 Sep 5. PMID: 24008587
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Substances : Terminalia
Diseases : Aging Skin, Dry Skin
Pharmacological Actions : Dermatologic Agents
Additional Keywords : Plant Extracts
[+]

Terminalia arjuna contributes to improvement of patients with refractory chronic congestive heart failure.May 01, 1995

Pubmed Data : Int J Cardiol. 1995 May;49(3):191-9. PMID: 7649665
Article Published Date : May 01, 1995
Study Type : Human Study
Additional Links
Substances : Arjuna, Terminalia
Diseases : Heart Failure
[+]

Anti Helicobacter pylori activity and gastrointestinal protective effects of Terminalia bellirica.Apr 08, 2025

Pubmed Data : J Ethnopharmacol. 2025 Apr 9 ;345:119569. Epub 2025 Mar 5. PMID: 40054639
Article Published Date : Apr 08, 2025
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Helicobacter Pylori Infection
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Plant Extracts
[+]

Anti-tumor activity of arjunolic acid against ehrlich ascites carcinoma cells.Jul 31, 2016

Pubmed Data : Biomed Pharmacother. 2016 Aug ;82:28-34. Epub 2016 May 3. PMID: 27470335
Article Published Date : Jul 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Breast Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Antineoplastic Agents, Apoptotic, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Chebulagic acid inhibits lipopolysaccharide-induced endometritis.May 31, 2025

Pubmed Data : J Reprod Immunol. 2025 Jun ;169:104464. Epub 2025 Feb 21. PMID: 40010025
Article Published Date : May 31, 2025
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Endometritis, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor
[+]

Terminalia chebula extract ameliorates the symptoms of atopic dermatitis.Jul 03, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytomedicine. 2022 Jul 4 ;104:154318. Epub 2022 Jul 4. PMID: 35830757
Article Published Date : Jul 03, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Atopic Dermatitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Interleukin-8 downregulation, NF-kappaB Inhibitor, STAT3 Inhibitor
[+]

Amelioration of cisplatin-induced nephrotoxicity in rats by triterpenoid saponin of Terminalia arjuna.Jul 31, 2015

Pubmed Data : Clin Exp Nephrol. 2015 Aug ;19(4):591-7. Epub 2014 Nov 12. PMID: 25389052
Article Published Date : Jul 31, 2015
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Chemotherapy-Induced Kidney Damage, Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Chemoprotective Agents, Renoprotective
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Anxiolytic-like and antidepressant-like effects of ethanol extract of Terminalia chebula.Oct 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Complement Med. 2021 Nov ;11(6):493-502. Epub 2021 May 1. PMID: 34765513
Article Published Date : Oct 31, 2021
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]

Arjunolic acid downregulates elevated blood sugar and pro-inflammatory cytokines.Jan 14, 2022

Pubmed Data : Life Sci. 2022 Jan 15 ;289:120232. Epub 2021 Dec 15. PMID: 34919901
Article Published Date : Jan 14, 2022
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Diabetes Mellitus: Type 2, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Hypoglycemic Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Arjunolic acid protects neurons from oxidative stress associated damage in focal cerebral ischemia and reperfusion.Sep 30, 2015

Pubmed Data : Pharmacol Rep. 2015 Oct ;67(5):890-5. Epub 2015 Feb 19. PMID: 26398381
Article Published Date : Sep 30, 2015
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Cerebral Ischemia
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Arjunolic acid, a peroxisome proliferator-activated receptor α agonist, regresses cardiac fibrosis by inhibiting non-canonical TGF-β signaling.Jan 05, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Biol Chem. 2017 10 6 ;292(40):16440-16462. Epub 2017 Aug 18. PMID: 28821620
Article Published Date : Jan 05, 2017
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Cardiac Hypertrophy, Cardiomegaly, Myocardial Fibrosis
Pharmacological Actions : Transforming growth factor beta (TGF-β) inhibitor
[+]

Biological activity and characterization of leaf and seed lectins from Terminalia brownii: Insights into their analgesic and antiulcer properties.Oct 29, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Heliyon. 2024 Oct 30 ;10(20):e39351. Epub 2024 Oct 18. PMID: 39498066
Article Published Date : Oct 29, 2024
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Gastric Ulcer
Pharmacological Actions : Analgesics, Anti-Ulcer Agents, Antinoceceptive , Gastroprotective
Additional Keywords : Natural Substances Versus Drugs
[+]

Cardio-protective effects of terminalia catappa leaves and terminalia chebula fruit extract in doxorubicin-induced cardiomyopathy.May 01, 2022

Pubmed Data : Biomarkers. 2022 May 2:1-8. Epub 2022 May 2. PMID: 35400254
Article Published Date : May 01, 2022
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Cardiomyopathy, Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Cardioprotective, Chemoprotective Agents
[+]

Chebulagic acid ameliorates DSS-induced colitis in mice by improving oxidative stress, inflammation and the gut microbiota.Dec 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2025 ;17(6):4101-4118. Epub 2025 Jun 15. PMID: 40672593
Article Published Date : Dec 31, 2024
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Chebulinic acid is a safe and effective antiangiogenic agent in collagen-induced arthritis in mice.Jan 22, 2020

Pubmed Data : Arthritis Res Ther. 2020 11 23 ;22(1):273. Epub 2020 Nov 23. PMID: 33225986
Article Published Date : Jan 22, 2020
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Arthritis
Pharmacological Actions : Anti-Angiogenic, Vascular Endothelial Growth Factor Inhibitors
[+]

Combined effects of Terminalia bellirica and Glycyrrhiza glabra on ameliorating cisplatin-induced nephrotoxicity.Dec 27, 2024

Pubmed Data : Nat Prod Res. 2024 Dec 28:1-9. Epub 2024 Dec 28. PMID: 39731476
Article Published Date : Dec 27, 2024
Study Type : Animal Study
Additional Links
Substances : Licorice, Terminalia
Diseases : Chemotherapy-Induced Kidney Damage, Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Chemoprotective Agents, Renoprotective
[+]

Curative effect of arjunolic acid from Terminalia arjuna in non-alcoholic fatty liver disease models.Oct 31, 2018

Pubmed Data : Biomed Pharmacother. 2018 Nov ;107:979-988. Epub 2018 Aug 23. PMID: 30257410
Article Published Date : Oct 31, 2018
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Hepatoprotective
[+]

Doses of Terminalia arjuna methanol extract can provide post-ischemic myocardial preservation. Sep 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anc Sci Life. 2015 Oct-Dec;35(2):79-84. PMID: 26865739
Article Published Date : Sep 30, 2015
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Ischemia: Myocardial
Pharmacological Actions : Antioxidants, Cardioprotective, Heat Shock Protein Inducer
[+]

Exploring the therapeutic potential of Terminalia chebula Retz. in alleviating the complications of letrozole-induced PCOS.Feb 28, 2025

Pubmed Data : Reprod Sci. 2025 Mar ;32(3):836-853. Epub 2025 Feb 12. PMID: 39939489
Article Published Date : Feb 28, 2025
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Antioxidants, Insulin-releasing
Additional Keywords : Plant Extracts
[+]

Gastric ulcer healing by chebulinic acid solid dispersion-loaded gastroretentive raft systems.Jan 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ther Deliv. 2022 Feb ;13(2):81-93. Epub 2022 Jan 25. PMID: 35075915
Article Published Date : Jan 31, 2022
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Gastroprotective
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Geum japonicum, Rhus javanica, Clove, and Terminalia chebula work synergistically with acyclovir against herpes simplex virus type 1 infection in vitro and in vivo. May 01, 1995

Pubmed Data : Antiviral Res. 1995 May;27(1-2):19-37. PMID: 7486956
Article Published Date : May 01, 1995
Study Type : Animal Study
Additional Links
Substances : Clove, Geum japonicum , Rhus javanica, Terminalia
Diseases : HSV-1
Pharmacological Actions : Antiviral Agents
[+]

Geum japonicum, Syzygium aromaticum (Clove), and Terminalia chebula inhibit Cytomegalovirus infection.Jan 01, 1998

Pubmed Data : Nippon Rinsho. 1998 Jan;56(1):156-60. PMID: 9465682
Article Published Date : Jan 01, 1998
Study Type : Animal Study
Additional Links
Substances : Clove, Geum japonicum , Sumac, Terminalia
Diseases : Cytomegalovirus Infections
Pharmacological Actions : Antiviral Agents
Additional Keywords : Drug: Ganciclovir, Superiority of Natural Substances versus Drugs
[+]

In vivo evaluation of the protective effects of arjunolic acid against lipopolysaccharide-induced septic myocardial injury.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PeerJ. 2022 ;10:e12986. Epub 2022 Feb 16. PMID: 35190789
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Lipopolysaccharide-Induced Toxicity, Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Interleukin-10 upregulation, Interleukin-4 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Molecular docking analysis of arjunolic acid from Terminalia arjuna with a coronary artery disease target APOE4.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Bioinformation. 2021 ;17(11):949-958. Epub 2021 Nov 30. PMID: 35655909
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Coronary Artery Disease
Pharmacological Actions : Cardioprotective
[+]

Pharmacodynamic evaluation suggested that TBR effectively led to hair regrowth in C57BL6 mice compared to minoxidil.Jan 29, 2025

Pubmed Data : J Ethnopharmacol. 2025 Jan 30 ;337(Pt 1):118778. Epub 2024 Sep 3. PMID: 39236776
Article Published Date : Jan 29, 2025
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Androgenic Alopecia
Pharmacological Actions : Antioxidants
Additional Keywords : Hair Regeneration, Natural Substances Versus Drugs, Plant Extracts
[+]

T. arjuna attenuates oxidative stress, apoptosis and improves antioxidant status in ISP-induced cardiotoxicity in rats.Nov 30, 2015

Pubmed Data : Indian J Exp Biol. 2015 Dec ;53(12):810-8. PMID: 26742326
Article Published Date : Nov 30, 2015
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Myocardial Infarction, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Cardioprotective
Additional Keywords : Plant Extracts
[+]

T. brownii crude extract and its solvent fractions showed a significant antihyperglycemic activity.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Exp Pharmacol. 2020 ;12:61-71. Epub 2020 Feb 20. PMID: 32110120
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
[+]

T. brownii dichloromethane extract has an immunoenhancing effect on innate immune responses.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2023 ;2023:9293335. Epub 2023 Feb 21. PMID: 36865749
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Immunodeficiency: Common Variable
Pharmacological Actions : Immunostimulatory
[+]

Terminalia arjuna protects mouse hearts against sodium flouride induced toxicity.Dec 01, 2008

Pubmed Data : J Med Food. 2008 Dec;11(4):733-40. PMID: 19053867
Article Published Date : Dec 01, 2008
Study Type : Animal Study
Additional Links
Substances : Arjuna, Terminalia
Diseases : Fluoride Toxicity
Pharmacological Actions : Cardioprotective
Problem Substances : Sodium Fluoride
Adverse Pharmacological Actions : Cardiotoxic
[+]

Terminalia bellirica ethanol extract ameliorates nonalcoholic fatty liver disease.Dec 25, 2022

Pubmed Data : J Ethnopharmacol. 2022 Dec 26:116082. Epub 2022 Dec 26. PMID: 36581163
Article Published Date : Dec 25, 2022
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Gastrointestinal Agents, Hepatoprotective
[+]

Terminalia catappa aqueous extract reduces hyperglycaemia and oxidative stress in diabetic-hypercholesterolemic rats.Dec 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ayurveda Integr Med. 2025 ;16(1):101025. Epub 2025 Jan 18. PMID: 39827649
Article Published Date : Dec 31, 2024
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Diabetes Mellitus: Type 2, Hypercholesterolemia, Hyperglycemia
Pharmacological Actions : Hypoglycemic Agents
[+]

Terminalia catappa aqueous leaf extract reverses insulin resistance, improves glucose transport and activates PI3K/AKT signalling.Jun 22, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2022 Jun 23 ;12(1):10711. Epub 2022 Jun 23. PMID: 35739183
Article Published Date : Jun 22, 2022
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Hypoglycemic Agents, Insulin Sensitizers
Additional Keywords : Plant Extracts
[+]

Terminalia chebula fruit extract attenuates LPS-induced acute lung injury in mouse model.May 31, 2025

Pubmed Data : Tissue Cell. 2025 Jun ;94:102805. Epub 2025 Feb 19. PMID: 39986129
Article Published Date : May 31, 2025
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Lipopolysaccharide-Induced Toxicity, Lung Damage, Oxidative Stress
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords : Plant Extracts
[+]

Terminalia chebula Retz. extract relieves gout arthritis.May 27, 2025

Pubmed Data : J Ethnopharmacol. 2025 May 28 ;348:119848. Epub 2025 Apr 21. PMID: 40268110
Article Published Date : May 27, 2025
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Gout
Pharmacological Actions : Anti-Inflammatory Agents, Xanthine oxidase inhibitor
Additional Keywords : Plant Extracts
[+]

Terminalia paniculata possesses hepatoprotective activity.May 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Trop Med. 2011 Jun ;4(6):466-9. PMID: 21771700
Article Published Date : May 31, 2011
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Acetaminophen (Tylenol) Toxicity , Liver Damage: Drug-Induced
Pharmacological Actions : Hepatoprotective
Additional Keywords : Plant Extracts
Problem Substances : Acetaminophen, Paracetamol
[+]

The present study indicated that hydromethanolic and aqueous bark extracts of T. brownii possess a promising antimalarial activity.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biochem Res Int. 2020 ;2020:9749410. Epub 2020 Jan 22. PMID: 32047669
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Malaria
Pharmacological Actions : Antimalarials
[+]

The protective effects of Terminalia laxiflora extract on hepato-nephrotoxicity induced by fipronil in male rats.Oct 31, 2020

Pubmed Data : Environ Sci Pollut Res Int. 2020 Nov ;27(31):39507-39515. Epub 2020 Jul 10. PMID: 32651782
Article Published Date : Oct 31, 2020
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Antioxidants, Hepatoprotective, Renoprotective, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
Problem Substances : Pesticides
[+]

The result from this study suggests significant antidiarrheal activity of Terminalia brownii leaves.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2024 ;15:1510171. Epub 2025 Jan 27. PMID: 39931513
Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Diarrhea
Pharmacological Actions : Antidiarrheals, Gastrointestinal Agents
[+]

Treatment with Terminalia chebula extract reduces insulin resistance, hyperglycemia and improves SIRT1 expression in type 2 diabetes.May 10, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Life (Basel). 2023 May 11 ;13(5). Epub 2023 May 11. PMID: 37240813
Article Published Date : May 10, 2023
Study Type : Animal Study
Additional Links
Substances : Terminalia
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Hypoglycemic Agents, Insulin Sensitizers, SIRT1 Activator
[+]

A systematic review of African natural products against gastric ulcers and Helicobacter pylori.Sep 25, 2022

Pubmed Data : J Ethnopharmacol. 2022 Sep 26:115698. Epub 2022 Sep 26. PMID: 36174808
Article Published Date : Sep 25, 2022
Study Type : Review
Additional Links
Substances : Hibiscus sabdariffa , Terminalia
Diseases : Gastric Ulcer, Helicobacter Pylori Infection
Pharmacological Actions : Anti-Bacterial Agents
[+]

Anti- candida activity of extracts containing ellagitannins, triterpenes and flavonoids of Terminalia brownii.Nov 14, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceutics. 2022 Nov 15 ;14(11). Epub 2022 Nov 15. PMID: 36432659
Article Published Date : Nov 14, 2022
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Terminalia
Diseases : Candida Infection
Pharmacological Actions : Anti-Bacterial Agents
[+]

Anti- toxoplasma effect of hydroalchohlic extract of Terminalia chebula.Sep 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Parasitol. 2021 Oct-Dec;16(4):631-640. PMID: 35082892
Article Published Date : Sep 30, 2021
Study Type : In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Toxoplasma gondii Infection
Pharmacological Actions : Antiparasitic Agents
[+]

Antibacterial and synergistic effects of Terminalia citrina leaf extracts against gastrointestinal pathogens.Jun 07, 2025

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antibiotics (Basel). 2025 Jun 8 ;14(6). Epub 2025 Jun 8. PMID: 40558183
Article Published Date : Jun 07, 2025
Study Type : In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Bacillus Cereus infection, Staphylococcus aureus: Methicillin-resistant (MRSA)
Pharmacological Actions : Anti-Bacterial Agents
[+]

Aqueous and methanolic extracts ofTerminalia arjuna has a definite antiosteoporotic effect.Nov 18, 2021

Pubmed Data : J Complement Integr Med. 2021 Nov 19. Epub 2021 Nov 19. PMID: 34798688
Article Published Date : Nov 18, 2021
Study Type : In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Chebulinic acid derived from triphala is a promising antitumour agent in human colorectal carcinoma cell lines.Dec 26, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2018 Dec 27 ;18(1):342. Epub 2018 Dec 27. PMID: 30587184
Article Published Date : Dec 26, 2018
Study Type : In Vitro Study
Additional Links
Substances : Terminalia, Triphala
Diseases : Colorectal Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
Additional Keywords : Plant Extracts
[+]

Chebulinic acid inhibits MDA-MB-231 breast cancer metastasis and promotes cell death.Nov 30, 2020

Pubmed Data : Cell Biol Int. 2020 Dec ;44(12):2553-2569. Epub 2020 Sep 16. PMID: 32902904
Article Published Date : Nov 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
[+]

Chebulinic acid isolated from aqueous extracts of Terminalia chebula Retz inhibits Helicobacter pylori infection.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Microbiol. 2024 ;15:1416794. Epub 2024 Oct 2. PMID: 39421559
Article Published Date : Dec 31, 2023
Study Type : In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Helicobacter Pylori Infection
Pharmacological Actions : Anti-Bacterial Agents
[+]

Chebulinic acid suppresses adipogenesis in 3T3-L1 preadipocytes.Jan 12, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 Jan 13 ;23(2). Epub 2022 Jan 13. PMID: 35055051
Article Published Date : Jan 12, 2022
Study Type : In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Obesity
Pharmacological Actions : Anti-Adipogenic
Additional Keywords : Anti-Obesity Agents
[+]

Ellagic acid from Terminalia arjuna fruits protects against chromium and cobalt toxicity in primary human lymphocytes.Aug 24, 2021

Pubmed Data : Biol Trace Elem Res. 2021 Aug 25. Epub 2021 Aug 25. PMID: 34432268
Article Published Date : Aug 24, 2021
Study Type : In Vitro Study
Additional Links
Substances : Ellagic Acid, Terminalia
Diseases : Heavy Metal Toxicity
Pharmacological Actions : Cytoprotective
Problem Substances : Cobalt
[+]

Exploring the therapeutic potential of Terminalia chebula against systemic candidiasis.Jun 30, 2025

Pubmed Data : Fitoterapia. 2025 Jul ;184:106649. Epub 2025 May 28. PMID: 40446938
Article Published Date : Jun 30, 2025
Study Type : In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Candidiasis
Pharmacological Actions : Antifungal Agents, Antioxidants, Immunomodulatory
Additional Keywords : Plant Extracts
[+]

High-throughput screening of dual-target inhibitors for SARS-CoV-2 main protease and papain-like protease from Chebulae Fructus.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Microbiol. 2024 ;15:1510665. Epub 2024 Dec 18. PMID: 39744403
Article Published Date : Dec 31, 2023
Study Type : In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Coronavirus Disease (Covid-19)
Pharmacological Actions : Antiviral Agents
[+]

Identification of chebulinic acid and chebulagic acid as novel influenza viral neuraminidase inhibitors.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Microbiol. 2020 ;11:182. Epub 2020 Feb 28. PMID: 32256457
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Influenza
Pharmacological Actions : Antiviral Agents, Neurominidase Inhibitor
[+]

In vitro antibacterial activity of neochebulinic acid from aqueous extract of Terminalia chebula Retz against Helicobacter pylori.Jul 23, 2025

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Med Ther. 2025 Jul 24 ;25(1):287. Epub 2025 Jul 24. PMID: 40707959
Article Published Date : Jul 23, 2025
Study Type : In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Helicobacter Pylori Infection
Pharmacological Actions : Anti-Bacterial Agents
[+]

Inhibition mechanisms of four ellagitannins from terminalia chebula fruits on acetylcholinesterase.Jul 07, 2023

Pubmed Data : Spectrochim Acta A Mol Biomol Spectrosc. 2023 Jul 8 ;302:123115. Epub 2023 Jul 8. PMID: 37453379
Article Published Date : Jul 07, 2023
Study Type : In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
[+]

Medicinal plants such as Lawsonia (Henna), Saraca, Syzygium cumini (Jambul), Terminalia belerica, Allium sativum (Garlic), and Datura stramonium have vibriocidal activity.Jun 01, 2009

Pubmed Data : Indian J Pharmacol. 2009 Jun;41(3):129-33. PMID: 20442821
Article Published Date : Jun 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Datura stramonium, Garlic, Henna, Jambul , Terminalia
Diseases : Cholera, Vibrio Infections
Pharmacological Actions : Anti-Bacterial Agents
[+]

n -butanol fraction of Terminalia catappa possesses anti-Candida albicans properties.Dec 31, 2024

Pubmed Data : Microb Pathog. 2025 Jan ;198:107133. Epub 2024 Nov 19. PMID: 39571833
Article Published Date : Dec 31, 2024
Study Type : In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Candida Albicans
Pharmacological Actions : Antifungal Agents
Additional Keywords : Plant Extracts
[+]

Preventive effect of combined Zingiber officinale and Terminalia chebula against DMBA-induced breast cancer rats via mTOR inhibition.Apr 05, 2021

Pubmed Data : Nutr Cancer. 2021 Apr 6:1-10. Epub 2021 Apr 6. PMID: 33821702
Article Published Date : Apr 05, 2021
Study Type : In Vitro Study
Additional Links
Substances : Ginger, Terminalia
Diseases : Breast Cancer
Pharmacological Actions : Chemopreventive
[+]

Results show that T. laxiflora and T. brownii contain antimycobacterial compounds of diverse polarities.Dec 04, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ethnopharmacol. 2018 Dec 5 ;227:82-96. Epub 2018 May 4. PMID: 29733942
Article Published Date : Dec 04, 2018
Study Type : In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Tuberculosis
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Plant Extracts
[+]

Tannins from T. chebula have a potential HCV NS3/4A inhibitory and host immune-modulatory activity.Feb 04, 2022

Pubmed Data : Molecules. 2022 Feb 5 ;27(3). Epub 2022 Feb 5. PMID: 35164341
Article Published Date : Feb 04, 2022
Study Type : In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Hepatitis C
Pharmacological Actions : Antiviral Agents, Immunomodulatory
Additional Keywords : Plant Extracts
[+]

Tannins in Terminalia bellirica inhibits hepatocellular carcinoma growth.Aug 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2022 Aug 31 ;154:113543. Epub 2022 Aug 31. PMID: 36057223
Article Published Date : Aug 30, 2022
Study Type : In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Liver Cancer
Pharmacological Actions : Immunomodulatory
Additional Keywords : Tumor Microenvironment
[+]

Terminalia catappa leaf extracts inhibited metastasis of A2058 and A375 melanoma cells.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:963589. Epub 2022 Sep 27. PMID: 36238547
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Melanoma
Pharmacological Actions : Anti-metastatic
[+]

Terminalia chebula gall extract has anti-aging properties in human skin fibroblasts.Apr 01, 2010

Pubmed Data : Pharm Biol. 2010 Apr;48(4):469-81. PMID: 20645728
Article Published Date : Apr 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Terminalia, Terminalia Chebula Gall Extract
Diseases : Aging Skin
Pharmacological Actions : Antioxidants, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor
Additional Keywords : Plant Extracts
[+]

Terminalia chebula water extract reduces joint inflammation by regulating cellular immunity in spleen cells of collagen-induced arthritis.May 31, 2024

Pubmed Data : Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2024 Jun ;40(6):494-500. PMID: 38952088
Article Published Date : May 31, 2024
Study Type : In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Arthritis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Transforming growth factor beta (TGF-β) inhibitor
Additional Keywords : Plant Extracts
[+]

Terminalia ivorensis demonstrates antioxidant properties and alters proliferation, genomic instability and migration of human colon cancer cells.Oct 22, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mutagenesis. 2024 Oct 23. Epub 2024 Oct 23. PMID: 39441622
Article Published Date : Oct 22, 2024
Study Type : In Vitro Study
Additional Links
Substances : Terminalia
Diseases : Colon Cancer
Pharmacological Actions : Anti-metastatic, Antioxidants, Antiproliferative , Apoptotic
[+]

The apoptotic potential activity of Terminalia Brownii extracts against various cancer cell lines.Jul 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2023 Aug 1 ;24(8):2629-2639. Epub 2023 Aug 1. PMID: 37642048
Article Published Date : Jul 31, 2023
Study Type : In Vitro Study
Additional Links
Substances : Kigagi, Terminalia
Diseases : Cancers: All
Pharmacological Actions : Apoptotic
Additional Keywords : Plant Extracts
[+]

The fruits of Phyllanthus emblica L., Quercus pedunculata (Oak) , Rumex cyprius, Terminalia bellerica, Terminalia chebula , and Terminalia horrida showed significant inhibitory activity against HIV virus. Apr 01, 1995

Pubmed Data : Chem Pharm Bull (Tokyo). 1995 Apr;43(4):641-8. PMID: 7541317
Article Published Date : Apr 01, 1995
Study Type : In Vitro Study
Additional Links
Substances : Oak, Phyllanthus emblica, Rumex, Terminalia
Diseases : HIV Infections
Pharmacological Actions : Reverse Transcriptase Inhibitors
Additional Keywords : Plant Extracts
[+]

The molecular mechanisms of cholangiocarcinoma cell inhibition by medicinal plants.Jan 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2017 Feb ;13(2):961-966. Epub 2016 Dec 12. PMID: 28356985
Article Published Date : Jan 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Moringa oleifera, Phyllanthus emblica, Terminalia, Turmeric
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

The potential of Terminalia chebula in alleviating mild cognitive impairment.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2024 ;15:1484040. Epub 2024 Oct 18. PMID: 39494343
Article Published Date : Dec 31, 2023
Study Type : Review
Additional Links
Substances : Terminalia
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

This study confirmed the potential of selected extracts of spices as effective natural food preservative in juices. Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Microbiol. 2016 ;2016:9015802. Epub 2016 Jan 4. PMID: 26880927
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Ashwagandha, Ginger, Gotu Kola, Indian Gooseberry, Mint, Terminalia, Turmeric
Diseases : Foodborne Pathogens: Prevention/Food Preservation
Pharmacological Actions : Antimicrobial, Food Preservatives
Additional Keywords : Fruit Juice, Plant Extracts
[+]

Thymus vulgaris (Thyme) and Terminalia chebula have profound activity against Clotrimazole-resistant Candida albicans.Jan 01, 2004

Pubmed Data : Fitoterapia. 2004 Jan;75(1):74-6. PMID: 14693224
Article Published Date : Jan 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Terminalia, Thyme
Diseases : Candidiasis
Pharmacological Actions : Antifungal Agents
Additional Keywords : Drug: Clotrimazole
[+]

T. arjuna can reverse cardiovascular damage done by smoking.Mar 01, 2004

Pubmed Data : Indian Heart J. 2004 Mar-Apr;56(2):123-8. PMID: 15377133
Article Published Date : Mar 01, 2004
Additional Links
Substances : Terminalia
[+]

T. arjuna improves blood lipid profile and inhibits atheroma in rabbits.Apr 01, 2009

Pubmed Data : Br J Nutr. 2009 Apr;101(8):1246-54. Epub 2009 Feb 25. PMID: 9891944
Article Published Date : Apr 01, 2009
Additional Links
Substances : Terminalia
[+]

Terminalia arjuna has anti-cancer activity.Sep 01, 2008

Pubmed Data : Phytother Res. 2008 Sep;22(9):1188-94. PMID: 18729254
Article Published Date : Sep 01, 2008
Additional Links
Substances : Terminalia
[+]

Terminalia arjuna has antioxidant and cholesterol-lowering activity.Feb 01, 2001

Pubmed Data : J Assoc Physicians India. 2001 Feb;49:231-5. PMID: 11225136
Article Published Date : Feb 01, 2001
Additional Links
Substances : Terminalia
[+]

Terminalia arjuna improves symptoms of chronic stable angina in men.Mar 01, 2002

Pubmed Data : Indian Heart J. 2002 Mar-Apr;54(2):170-5. PMID: 12086380
Article Published Date : Mar 01, 2002
Additional Links
Substances : Terminalia

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