Tetrahydrocurcumin

Name	AC	CK
Oxidative Stress	21	38
Diabetes Mellitus: Type 2	10	20
Inflammation	7	11
Breast Cancer	4	8
Cervical Cancer	3	6
High Fat Diet	3	6
Obesity	3	6
Traumatic Brain Injury	3	6
Lipid Peroxidation	3	5
Nonalcoholic fatty liver disease (NAFLD)	3	5
Aging	2	4
Hyperglycemia	2	4
Hypertension	2	4
Myocardial Infarction	2	4
Breast Cancer: Triple Negative	1	3
Cadmium Poisoning	2	3
Cardiac Hypertrophy	2	3
Influenza	2	3
Lipopolysaccharide-Induced Toxicity	2	3
Metabolic Diseases	2	3
Parkinson's Disease	2	3
Ultraviolet Radiation Induced Damage	2	3
Aging Skin	1	2
Altitude Sickness	1	2
Alzheimer's Disease	2	2
Antibiotic Toxicity	1	2
Arsenic Poisoning	1	2
Asthma	1	2
Atopic Dermatitis	1	2
Brain Inflammation	1	2
Brain Injury: Traumatic	2	2
Brain Ischemia	1	2
Cancers: All	2	2
Cardiomyopathy	1	2
Cardiovascular Diseases	1	2
Chemically-Induced Liver Damage	2	2
Chemotherapy-Induced Toxicity: Cisplatin	1	2
Chemotherapy-Induced Toxicity: Vincristine	1	2
Colon Cancer	1	2
Depression	1	2
Diabetes: Cognitive Dysfunction	1	2
Diabetes: Kidney Function	1	2
Diabetes: Liver Disease	1	2
Diabetic Nephropathy	1	2
Dyslipidemias	1	2
Epstein-Barr Virus Infections	1	2
Fatty Liver	1	2
Fibrosis	1	2
Fungus Diseases	1	2
Gastric Ulcer	1	2
Glioma	2	2
Hepatic Steatosis	1	2
High Fructose Diet	1	2
Hypoxia: Brain	1	2
Insulin Resistance	1	2
Iron Overload	1	2
Kidney Damage	1	2
Kidney Damage: Chemically-Induced	2	2
Leukemia	1	2
Neurodegenerative Diseases	1	2
Osteoarthritis	1	2
Phthalate Toxicity	1	2
Postmenopausal Disorders	1	2
Spinal Cord Injuries	1	2
Stroke: Ischemic	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Tumors	1	2
Acetaminophen (Tylenol) Toxicity	1	1
Acute Myeloid Leukemia	1	1
Brain: Oxidative Stress	1	1
Cancer Metastasis	1	1
Cancers: Drug Resistant	1	1
Cancers: Multi-Drug Resistant	1	1
Carcinoma: Non-Small-Cell Lung	1	1
Cerebral Ischemia	1	1
Esophageal Cancer	1	1
Eye Damage	1	1
Eye Diseases	1	1
Fibrosarcoma	1	1
HIV Infections	1	1
Homocysteine: Elevated	1	1
Influenza A	1	1
Liver Cancer	1	1
Liver Damage: Drug-Induced	1	1
Lung Cancer	1	1
Neurological Conditions	1	1
Oral Cancer	1	1
Osteosarcoma	1	1
Ovarian Cancer	1	1
Radiation Induced Illness	1	1
Skin Diseases	1	1
Squamous cell carcinoma	1	1

Name	AC	CK
Antioxidants	29	50
Anti-Inflammatory Agents	17	30
Neuroprotective Agents	15	24
Apoptotic	12	21
Antiproliferative	9	15
Hepatoprotective	9	14
Renoprotective	7	12
Anti-Apoptotic	7	11
Anticarcinogenic Agents	6	11
Cardioprotective	6	11
Cell cycle arrest	3	8
Hypolipidemic	4	8
Tumor Necrosis Factor (TNF) Alpha Inhibitor	4	8
Antihypertensive Agents	4	7
Caspase-3 Activation	2	6
Cyclooxygenase 2 Inhibitors	3	6
Hypoglycemic Agents	3	6
Angiogenesis Inhibitors	3	5
Bcl-2 protein down-regulation	1	5
Nrf2 activation	3	5
P21 Activation	1	5
Anti-Fibrotic	2	4
Antiviral Agents	3	4
Chemoprotective Agents	2	4
Chemotherapeutic	3	4
Interleukin-6 Downregulation	2	4
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	2	4
Matrix metalloproteinase-3 (MMP-3) inhibitor	2	4
Superoxide Dismutase Up-regulation	2	4
Vascular Endothelial Growth Factor Inhibitors	2	4
Anti-metastatic	3	3
Malondialdehyde Down-regulation	2	3
Photoprotective	2	3
Anti-Angiogenic	1	2
Anti-Ulcer Agents	1	2
Antidepressive Agents	1	2
Antifungal Agents	1	2
Antineoplastic Agents	2	2
Antinoceceptive	1	2
Brain-derived neurotrophic factor modulator	1	2
Chemopreventive	2	2
Gastrointestinal Agents	1	2
Gastroprotective	1	2
Heme oxygenase-1 up-regulation	1	2
Hypoxia-inducible factor-1 (HIF-1) inhibitor	1	2
Interleukin-1 beta downregulation	1	2
Interleukin-17 downregulation	1	2
Interleukin-4 downregulation	1	2
Interleukin-5 downregulation	1	2
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	2
Matrix metalloproteinase-9 (MMP-9) inhibitor	1	2
NF-kappaB Inhibitor	1	2
Anti-Bacterial Agents	1	1
Autophagy Inhibitors	1	1
Caspase-9 Activation	1	1
Chemosensitizer	1	1
Cyclin D1 Down-Regulation	1	1
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	1	1
Radiosensitizer	1	1

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Short-term intravenous dosing of liposomal curcumin appears to be safe up to a dose of 120 mg/m2.Dec 31, 2014

Article Published Date : Jun 24, 2015

Study Type : Animal Study

Additional Links

Substances : Tetrahydrocurcumin

Diseases : Arsenic Poisoning

Pharmacological Actions : Antioxidants, Hepatoprotective

Problem Substances : Arsenic

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Antiviral effects of curcumin derivatives as potent inhibitors of influenza H1N1 neuraminidase.Apr 03, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Saudi Pharm J. 2023 Sep ;31(9):101727. Epub 2023 Aug 2. PMID: 37638219

Article Published Date : Aug 31, 2023

Study Type : Animal Study

Additional Links

Substances : Tetrahydrocurcumin

Diseases : Hyperglycemia

Pharmacological Actions : Hypoglycemic Agents

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Supplementation with tetrahydrocurcumin enhances the therapeutic effects of dexamethasone in a murine model of allergic asthma.Dec 31, 2019

Click here to read the entire abstract

Pubmed Data : Int Arch Allergy Immunol. 2020 ;181(11):822-830. Epub 2020 Aug 12. PMID: 32784298

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Genes Nutr. 2016 ;11:2. Epub 2016 Mar 17. PMID: 27482294

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Curcumin, Tetrahydrocurcumin

Diseases : Osteoarthritis, Postmenopausal Disorders

Pharmacological Actions : Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Matrix metalloproteinase-3 (MMP-3) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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