Theanine

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81 Diseases Researched for Theanine
NameACCKFocus
Cognitive Decline/Dysfunction525Locked
Anxiety423Locked
Stress423Locked
Immune Disorders: Low Immune Function322Locked
Athletic Performance220Locked
Athletic Performance: Recovery 220Locked
Depression314Locked
Cancers: All211Locked
Attention Deficit Disorder with Hyperactivity110Locked
Brain Wave Dysfunction: Low Alpha Band Activity110Locked
Cortisol: High110Locked
Depressive Disorder110Locked
Immune Dysregulation: TH1/TH2 imbalance110Locked
Influenza A110Locked
Influenza in Swine110Locked
Insomnia110Locked
Lymphopenia110Locked
Neutrophils: Elevated110Locked
Parkinson's Disease610Locked
Schizophrenia110Locked
Swine Flu Associated Virus110Locked
Tourette Syndrome110Locked
Alzheimer's Disease47Locked
Inflammation35Locked
Oxidative Stress35Locked
Chemotherapy-Induced Toxicity: Peripheral Neuropathy24Locked
Colitis24Locked
Neurodegenerative Diseases24Locked
Sleep Disorders24Locked
Brain Ischemia23Locked
Liver Cancer23Locked
Liver Damage23Locked
Memory Disorders23Locked
Nonalcoholic fatty liver disease (NAFLD)13Locked
Aging12Locked
Aging: Brain 12Locked
Aluminum Toxicity 12Locked
Anxiety Disorders12Locked
Appetite Disorders12Locked
Asthma12Locked
Brain Inflammation 12Locked
Cerebral Ischemia12Locked
Cervical Cancer12Locked
Chemotherapy-Induced Toxicity: Cyclophosphamide12Locked
Chemotherapy-Induced Toxicity: Doxorubicin12Locked
Chemotherapy-Induced Toxicity: Oxaliplatin12Locked
Corneal Neovascularization12Locked
Excitotoxicity 12Locked
Hyperinsulinism12Locked
Hypertension12Locked
Inflammatory Bowel Diseases12Locked
Ischemia12Locked
Kidney Damage12Locked
Lipid Peroxidation12Locked
Lipopolysaccharide-Induced Toxicity12Locked
Memory Loss12Locked
Mood Disorders12Locked
Neuropathic Pain12Locked
Nicotine/Tobacco Toxicity 12Locked
Obesity12Locked
Osteoarthritis: Knee12Locked
Postnatal Care: Breastfeeding12Locked
Prostate Cancer12Locked
Radiation12Locked
Retinopathy of Prematurity12Locked
Retrolental Fibroplasia12Locked
Sciatic Nerve Crush Injury12Locked
Sepsis12Locked
Spinal Cord Injuries12Locked
Testicular Injury: Chemical/Metal Induced12Locked
Advanced Glycation End products (AGE)11Locked
Aging: Liver11Locked
Cancer Metastasis11Locked
Food Allergies11Locked
Hepatoma11Locked
Leukemia11Locked
Melanoma11Locked
Non-Small-Cell Lung Carcinoma11Locked
Ovarian Cancer11Locked
Pesticide Toxicity 11Locked
Psoriasis11Locked
36 Pharmacological Actions Researched for Theanine
NameACCKFocus
Neuroprotective Agents2169Locked
Anti-Inflammatory Agents1628Locked
Anti-Anxiety Agents525Locked
Antidepressive Agents424Locked
Antioxidants916Locked
Immunomodulatory312Locked
Anti-Bacterial Agents110Locked
Hypnotics and Sedatives110Locked
Interleukin-10 downregulation110Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor59Locked
Anti-metastatic58Locked
Anti-Apoptotic47Locked
Antiproliferative 35Locked
Hepatoprotective25Locked
Interleukin-1 beta downregulation35Locked
Interleukin-6 Downregulation35Locked
NF-kappaB Inhibitor35Locked
Chemoprotective Agents24Locked
Gastroprotective24Locked
Malondialdehyde Down-regulation24Locked
Apoptotic23Locked
Cytoprotective23Locked
Anti-Allergic Agents12Locked
Anxiolytic12Locked
Cyclooxygenase 2 Inhibitors12Locked
Gastrointestinal Agents12Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor12Locked
Neuritogenic12Locked
Nitric Oxide Inhibitor12Locked
Radioprotective12Locked
Renoprotective12Locked
Anti-Glycation Agents11Locked
Antineoplastic Agents11Locked
Enzyme Inhibitors11Locked
Interleukin-17 downregulation11Locked
Interleukin-23 Downregulation11Locked

View the Evidence:
78 Abstracts with Theanine Research

[+]

A combination of Magnolia, Epimedium, Theanine, Beta Sitosterol, Phosphatidylcholine reduces serum cortisol responses to physical stress. Aug 01, 2006

Pubmed Data : Arch Dermatol. 2006 Aug;142(8):985-90. PMID: 15877297
Article Published Date : Aug 01, 2006
Study Type : Human Study
Additional Links
Substances : Beta Sitosterol, Epimedium, Magnolia, Phosphatidylcholine, Theanine
Diseases : Cortisol: High
[+]

Among healthcare workers for the elderly, taking green tea catechins and theanine may be effective prophylaxis for influenza infection.Jan 01, 2011

Pubmed Data : BMC Complement Altern Med. 2011 ;11:15. Epub 2011 Feb 21. PMID: 21338496
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Substances : Catechin , Green Tea, Tea, Theanine
Diseases : Influenza A
Additional Keywords : Health Care Workers, Plant Extracts
[+]

Cystine (a dipeptide of cysteine) and theanine supplementation restores high-Intensity resistance exercise-induced atenuation of natural killer cell activity in well-trained men.Feb 09, 2010

Pubmed Data : J Strength Cond Res. 2010 Feb 9. Epub 2010 Feb 9. PMID: 20145562
Article Published Date : Feb 09, 2010
Study Type : Human Study
Additional Links
Substances : Cysteine (see N-Acetylcysteine), Theanine
Diseases : Athletic Performance: Recovery , Immune Disorders: Low Immune Function
[+]

Effects of L-theanine-caffeine combination on sustained attention and inhibitory control among children with ADHD.Jan 03, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2020 08 4 ;10(1):13072. Epub 2020 Aug 4. PMID: 32753637
Article Published Date : Jan 03, 2020
Study Type : Human Study
Additional Links
Substances : Theanine
Diseases : Attention Deficit Disorder with Hyperactivity
Pharmacological Actions : Neuroprotective Agents
[+]

L-cystine and l-theanine may contribute to enhancing the immune response against the H1N1 virus. Dec 01, 2008

Pubmed Data : Geriatr Gerontol Int. 2008 Dec;8(4):243-50. PMID: 19149835
Article Published Date : Dec 01, 2008
Study Type : Human Study
Additional Links
Substances : Cysteine (see N-Acetylcysteine), Theanine
Diseases : Influenza in Swine, Swine Flu Associated Virus
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

L-Theanine adjunct to risperidone in the treatment of chronic schizophrenia inpatients.Nov 30, 2023

Pubmed Data : Psychopharmacology (Berl). 2023 Dec ;240(12):2631-2640. Epub 2023 Sep 12. PMID: 37697164
Article Published Date : Nov 30, 2023
Study Type : Human Study
Additional Links
Substances : Theanine
Diseases : Schizophrenia
Additional Keywords : Natural Substance/Drug Synergy
[+]

l-theanine adjunct to sertraline for major depressive disorder.Jul 14, 2023

Pubmed Data : J Affect Disord. 2023 Jul 15 ;333:38-43. Epub 2023 Apr 19. PMID: 37084960
Article Published Date : Jul 14, 2023
Study Type : Human Study
Additional Links
Substances : Theanine
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]

l-theanine has multiple beneficial effects on depressive symptoms, anxiety, sleep disturbance and cognitive impairments in patients with MDD.Jul 10, 2016

Pubmed Data : Acta Neuropsychiatr. 2016 Jul 11:1-8. Epub 2016 Jul 11. PMID: 27396868
Article Published Date : Jul 10, 2016
Study Type : Human Study
Additional Links
Substances : Theanine
Diseases : Anxiety, Depressive Disorder
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
[+]

L-theanine has the potential to promote mental health in the general population with stress-related ailments and cognitive impairments.Oct 02, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Oct 3 ;11(10). Epub 2019 Oct 3. PMID: 31623400
Article Published Date : Oct 02, 2019
Study Type : Human Study
Additional Links
Substances : Theanine
Diseases : Stress
Pharmacological Actions : Neuroprotective Agents
[+]

L-theanine improves neurophysiological measures of attention in a dose-dependent manner.Aug 10, 2020

Pubmed Data : Nutr Neurosci. 2020 Aug 11:1-11. Epub 2020 Aug 11. PMID: 32777998
Article Published Date : Aug 10, 2020
Study Type : Human Study
Additional Links
Substances : Theanine
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Dose Response
[+]

l-theanine may contribute to improving attention, thus enhancing working memory and executive functions.Mar 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Med Food. 2021 Apr ;24(4):333-341. Epub 2021 Mar 22. PMID: 33751906
Article Published Date : Mar 31, 2021
Study Type : Human Study
Additional Links
Substances : Theanine
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

L-Theanine reduces psychological and physiological stress responses.Jan 01, 2007

Pubmed Data : Biol Psychol. 2007 Jan;74(1):39-45. Epub 2006 Aug 22. PMID: 16930802
Article Published Date : Jan 01, 2007
Study Type : Human Study
Additional Links
Substances : Theanine
Diseases : Stress
[+]

L-theanine significantly increases activity in the alpha frequency band resulting in increased relaxation of the mind without drowsiness. Jan 01, 2008

Pubmed Data : Asia Pac J Clin Nutr. 2008;17 Suppl 1:167-8. PMID: 18296328
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Substances : Theanine
Diseases : Brain Wave Dysfunction: Low Alpha Band Activity
[+]

Supplementation with L-theanine seems to exert a beneficial effect on a disrupted Th1/Th2 balance in elite athletes.Feb 14, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Int Soc Sports Nutr. 2019 Feb 15 ;16(1):7. Epub 2019 Feb 15. PMID: 30770758
Article Published Date : Feb 14, 2019
Study Type : Human Study
Additional Links
Substances : Theanine
Diseases : Athletic Performance, Immune Dysregulation: TH1/TH2 imbalance
Therapeutic Actions : Exercise
Pharmacological Actions : Immunomodulatory, Interleukin-10 downregulation
[+]

The hypnotic efficacy of oral melatonin 3 mg was better than oral L-theanine 200 mg in cancer patients having insomnia.Dec 31, 2023

Pubmed Data : Indian J Palliat Care. 2024 ;30(2):176-181. Epub 2024 May 3. PMID: 38846134
Article Published Date : Dec 31, 2023
Study Type : Human Study
Additional Links
Substances : Melatonin, Theanine
Diseases : Cancers: All, Insomnia
Pharmacological Actions : Hypnotics and Sedatives
[+]

The theanine content of tea may be responsible for it significantly increasing immune function in users, relative to coffee consumption.May 13, 2003

Pubmed Data : Proc Natl Acad Sci U S A. 2003 May 13;100(10):6009-14. Epub 2003 Apr 28. PMID: 12719524
Article Published Date : May 13, 2003
Study Type : Human Study
Additional Links
Substances : Black Tea, Coffee, Green Tea, Theanine
Diseases : Immune Disorders: Low Immune Function
Pharmacological Actions : Anti-Bacterial Agents
[+]

Theanine/cysteine intake suppresses exercise-induced neutrophilia and lymphopenia in athletes.Jan 01, 2010

Pubmed Data : J Int Soc Sports Nutr. 2010;7(1):23. Epub 2010 Jun 4. PMID: 20525371
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Substances : Cysteine (see N-Acetylcysteine), Theanine
Diseases : Athletic Performance, Athletic Performance: Recovery , Lymphopenia, Neutrophils: Elevated
[+]

Use of nutritional supplements based on L-theanine and vitamin B6 in children with Tourette syndrome, with anxiety disorders.Feb 17, 2022

Pubmed Data : Nutrients. 2022 Feb 18 ;14(4). Epub 2022 Feb 18. PMID: 35215501
Article Published Date : Feb 17, 2022
Study Type : Human Study
Additional Links
Substances : Theanine, Vitamin B-6
Diseases : Anxiety, Tourette Syndrome
Pharmacological Actions : Anti-Anxiety Agents
[+]

L-theanine prevents progression of nonalcoholic hepatic steatosis.Apr 14, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Metab (Lond). 2022 Apr 15 ;19(1):29. Epub 2022 Apr 15. PMID: 35428314
Article Published Date : Apr 14, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Theanine
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Hepatoprotective
[+]

Protective effects of L-theanine on rats with dextran sulfate sodium-induced inflammatory bowel disease.Jul 27, 2020

Pubmed Data : Arch Pharm Res. 2020 Jul 28. Epub 2020 Jul 28. PMID: 32720164
Article Published Date : Jul 27, 2020
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Gastrointestinal Agents, Gastroprotective
[+]

Ameliorative effects of L-theanine on dextran sulfate sodium induced colitis.Jan 10, 2020

Pubmed Data : Food Res Int. 2020 11 ;137:109409. Epub 2020 Jun 9. PMID: 33233096
Article Published Date : Jan 10, 2020
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Gastroprotective
[+]

Antarctic krill oil exhibited synergistic effects with nobiletin and theanine in ameliorating memory and cognitive deficiency.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Aging Neurosci. 2022 ;14:964077. Epub 2022 Sep 16. PMID: 36185487
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Krill, Nobiletin , Theanine
Diseases : Aging: Brain , Cognitive Decline/Dysfunction, Memory Disorders
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Natural Substance Synergy
[+]

Cystine and theanine improve survival after gut ischemia-reperfusion.Dec 31, 2017

Pubmed Data : Ann Nutr Metab. 2018 ;73(2):131-137. Epub 2018 Jul 27. PMID: 30056446
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Cystine, Theanine
Diseases : Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Cystine and Theanine may be beneficial for preventing oxaliplatin-induced peripheral neuropathy.Jul 28, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2020 Jul 29 ;10(1):12665. Epub 2020 Jul 29. PMID: 32728157
Article Published Date : Jul 28, 2020
Study Type : Animal Study
Additional Links
Substances : Cystine, Theanine
Diseases : Chemotherapy-Induced Toxicity: Oxaliplatin, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

GABA and l-theanine mixture decreases sleep latency and improves NREM sleep.Nov 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2019 Dec ;57(1):65-73. PMID: 30707852
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : GABA (gamma-Aminobutyric Acid), Theanine
Diseases : Sleep Disorders
Additional Keywords : Natural Substance Synergy
[+]

L-theanine alleviates airway inflammation in asthma.Dec 31, 2016

Pubmed Data : Food Chem Toxicol. 2017 Jan ;99:162-169. Epub 2016 Nov 29. PMID: 27908701
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Asthma, Inflammation
Pharmacological Actions : Anti-Allergic Agents, Anti-Inflammatory Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

L-Theanine alleviates MPTP-induced Parkinson's disease.Jan 30, 2023

Pubmed Data : Int J Biol Macromol. 2023 Jan 31 ;226:90-101. Epub 2022 Dec 8. PMID: 36502788
Article Published Date : Jan 30, 2023
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

L-theanine ameliorate depressive-like behavior in a chronic unpredictable mild stress.Nov 24, 2018

Pubmed Data : Phytother Res. 2018 Nov 25. Epub 2018 Nov 25. PMID: 30474152
Article Published Date : Nov 24, 2018
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]

L-theanine ameliorated rotenone-induced Parkinsonism-like symptoms.Jan 05, 2022

Pubmed Data : Neurotox Res. 2022 Jan 6. Epub 2022 Jan 6. PMID: 34988886
Article Published Date : Jan 05, 2022
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

l-Theanine ameliorates motor deficit, mitochondrial dysfunction, and neurodegeneration against chronic tramadol induced rats model of Parkinson's disease.Jun 30, 2021

Pubmed Data : Drug Chem Toxicol. 2021 Jul 1:1-12. Epub 2021 Jul 1. PMID: 34210222
Article Published Date : Jun 30, 2021
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

L-theanine and Neumentix mixture improves sleep quality and modulates brain neurotransmitter levels.Mar 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Palliat Med. 2021 Apr ;10(4):4572-4581. PMID: 33966405
Article Published Date : Mar 31, 2021
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Sleep Disorders
[+]

L-Theanine appears to improve cognitive function in mice. May 01, 2008

Pubmed Data : Biosci Biotechnol Biochem. 2008 May;72(5):1356-9. Epub 2008 May 7. PMID: 18460792
Article Published Date : May 01, 2008
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Memory Loss
[+]

L-theanine attenuates beta-amyloid-induced cognitive dysfunction and neurotoxicity. Dec 01, 2009

Pubmed Data : Free Radic Biol Med. 2009 Dec 1;47(11):1601-10. Epub 2009 Sep 16. PMID: 19766184
Article Published Date : Dec 01, 2009
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction
[+]

L-theanine attenuates LPS-induced motor deficit in experimental rat model of Parkinson's disease.Jun 30, 2023

Pubmed Data : Psychopharmacology (Berl). 2023 Jul ;240(7):1493-1508. Epub 2023 May 16. PMID: 37191688
Article Published Date : Jun 30, 2023
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Lipopolysaccharide-Induced Toxicity, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

L-theanine attenuates nicotine reward and withdrawal signs.Jun 10, 2023

Pubmed Data : Neurosci Lett. 2023 Jun 11 ;807:137279. Epub 2023 Apr 25. PMID: 37105354
Article Published Date : Jun 10, 2023
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Nicotine/Tobacco Toxicity
Pharmacological Actions : Anti-Anxiety Agents
[+]

l-Theanine improves functional recovery after traumatic spinal cord injury in rats.Dec 04, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Formos Med Assoc. 2019 Dec 5. Epub 2019 Dec 5. PMID: 31812333
Article Published Date : Dec 04, 2019
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Spinal Cord Injuries
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor
[+]

L-theanine protects against glutamate-induced excitotoxicity in a mouse model.Jul 14, 2010

Pubmed Data : Neuroscience. 2010 Jul 14;168(3):778-86. Epub 2010 Apr 21. PMID: 20416364
Article Published Date : Jul 14, 2010
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Alzheimer's Disease, Excitotoxicity
[+]

l-theanine protects bladder function by suppressing chronic sympathetic hyperactivity in spontaneously hypertensive rat.Nov 13, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Metabolites. 2021 Nov 14 ;11(11). Epub 2021 Nov 14. PMID: 34822436
Article Published Date : Nov 13, 2021
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Hypertension
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation
[+]

L-theanine reduced the development of knee osteoarthritis.Jul 02, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Jul 3 ;12(7). Epub 2020 Jul 3. PMID: 32635404
Article Published Date : Jul 02, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Theanine
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Risk Reduction
[+]

L-theanine significantly and dose-dependently inhibited sepsis induced liver and kidney injury.May 14, 2020

Pubmed Data : Life Sci. 2020 May 15 ;249:117502. Epub 2020 Mar 3. PMID: 32142764
Article Published Date : May 14, 2020
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Kidney Damage, Liver Damage, Oxidative Stress, Sepsis
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Renoprotective
[+]

L-theanine supports immune function.Apr 24, 2006

Pubmed Data : Neurosci Lett. 2006 Apr 24;397(3):219-23. Epub 2006 Jan 6. PMID: 18254876
Article Published Date : Apr 24, 2006
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Immune Disorders: Low Immune Function
[+]

L-theanine suppresses food intake in rats, and may lower insulin levels.May 01, 2008

Pubmed Data : Biosci Biotechnol Biochem. 2008 May;72(5):1352-5. Epub 2008 May 7. PMID: 18460793
Article Published Date : May 01, 2008
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Appetite Disorders, Hyperinsulinism
[+]

L-theanine suppresses the metastasis of prostate cancer by downregulating MMP9 and Snail.Dec 31, 2020

Pubmed Data : J Nutr Biochem. 2021 03 ;89:108556. Epub 2020 Nov 26. PMID: 33249185
Article Published Date : Dec 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Theanine
Diseases : Prostate Cancer
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

L-theanine works synergistically with the drug midazolam to induce an anxiolytic effect. Aug 01, 2010

Pubmed Data : J Altern Complement Med. 2010 Aug;16(8):875-82. PMID: 20108732
Article Published Date : Aug 01, 2010
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Anxiety Disorders
Pharmacological Actions : Anxiolytic
Additional Keywords : Drug: Midazolam, Drug-Plant-Vitamin Synergies
[+]

L-theanine, Magnolia officinalis, and Melissa officinalis may represent a useful and safe candidate for the management of mood disorders.Jun 16, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Jun 17 ;12(6). Epub 2020 Jun 17. PMID: 32560413
Article Published Date : Jun 16, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lemon Balm, Magnolia, Theanine
Diseases : Anxiety, Depression, Mood Disorders
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
[+]

Neuroprotective effect of l-theanine in a rat model of chronic constriction injury of sciatic nerve-induced neuropathic pain.Sep 12, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Formos Med Assoc. 2021 Sep 13. Epub 2021 Sep 13. PMID: 34531102
Article Published Date : Sep 12, 2021
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Neuropathic Pain, Sciatic Nerve Crush Injury
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Protective effect of l-theanine against DSS-induced colitis.Nov 30, 2021

Pubmed Data : J Agric Food Chem. 2021 Dec 1 ;69(47):14192-14203. Epub 2021 Nov 16. PMID: 34784210
Article Published Date : Nov 30, 2021
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Colitis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Protective effect of l-theanine on cyclophosphamide-induced testicular toxicity.May 30, 2023

Pubmed Data : J Agric Food Chem. 2023 May 31 ;71(21):8050-8060. Epub 2023 May 17. PMID: 37198140
Article Published Date : May 30, 2023
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Cytoprotective
[+]

Protective effects of a cystine and theanine mixture against acute radiation injury.Jul 31, 2020

Pubmed Data : Environ Toxicol Pharmacol. 2020 Aug ;78:103395. Epub 2020 Apr 17. PMID: 32325407
Article Published Date : Jul 31, 2020
Study Type : Animal Study
Additional Links
Substances : Cystine, Theanine
Diseases : Radiation
Pharmacological Actions : Radioprotective
[+]

Protective effects of L-theanine against doxorubicin-induced nephrotoxicity.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2018 Dec ;108:1524-1534. Epub 2018 Oct 9. PMID: 30372854
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Antioxidants, Chemoprotective Agents
[+]

Stress-reducing effect of cookies containing matcha green tea: essential ratio among theanine, arginine, caffeine and epigallocatechin gallate.Apr 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Heliyon. 2019 May ;5(5):e01653. Epub 2019 May 7. PMID: 31111111
Article Published Date : Apr 30, 2019
Study Type : Animal Study
Additional Links
Substances : Green Tea, Theanine
Diseases : Stress
[+]

The combination of luteolin and l-theanine improved Alzheimer disease-like symptoms.Nov 30, 2018

Pubmed Data : Nutr Res. 2018 Dec ;60:116-131. Epub 2018 Oct 2. PMID: 30527255
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Luteolin, Theanine
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Theanine improves high-dose epigallocatechin-3-gallate-induced lifespan reduction in caenorhabditis elegans.Jun 16, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2021 Jun 17 ;10(6). Epub 2021 Jun 17. PMID: 34204441
Article Published Date : Jun 16, 2021
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate), Theanine
Diseases : Aging
Pharmacological Actions : Antioxidants
[+]

Theanine may assist in healthy brain function development in the offspring of those who consume it while lactating. Mar 01, 2007

Pubmed Data : Atherosclerosis. 2007 Mar;191(1):162-7. Epub 2006 Apr 17. PMID: 17904164
Article Published Date : Mar 01, 2007
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Postnatal Care: Breastfeeding
Pharmacological Actions : Neuritogenic
[+]

Theanine prevents memory impairment induced by repeated cerebral ischemia in rats. Jul 01, 2008

Pubmed Data : Cancer Res. 2008 Jul 1;68(13):5345-54. PMID: 17705146
Article Published Date : Jul 01, 2008
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Brain Ischemia, Cerebral Ischemia
Pharmacological Actions : Neuroprotective Agents
[+]

Theanine significantly enhanced the repression of liver cancer cell growth in combination with anticancer drug pirarubicin.Sep 08, 2016

Pubmed Data : J Agric Food Chem. 2016 Sep 9. Epub 2016 Sep 9. PMID: 27569455
Article Published Date : Sep 08, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Theanine
Diseases : Liver Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , NF-kappaB Inhibitor
Additional Keywords : Natural Substance/Drug Synergy
[+]

Theanine significantly suppressed human cervical tumor growth in tumor-bearing nude mice without toxicity.Sep 05, 2016

Pubmed Data : Eur J Pharmacol. 2016 Sep 6. Epub 2016 Sep 6. PMID: 27612630
Article Published Date : Sep 05, 2016
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Cervical Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
[+]

Theanine suppresses oxygen-induced retinal neovascularization associated in a rat model of retinopathy. Aug 01, 2008

Pubmed Data : Nippon Ganka Gakkai Zasshi. 2008 Aug;112(8):669-73. PMID: 18767491
Article Published Date : Aug 01, 2008
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Corneal Neovascularization, Retinopathy of Prematurity, Retrolental Fibroplasia
[+]

These results suggest a potential role of L-Theanine in combating diet-induced obesity.Apr 15, 2021

Pubmed Data : Diabetes. 2021 Apr 16. Epub 2021 Apr 16. PMID: 33863801
Article Published Date : Apr 15, 2021
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Obesity
Additional Keywords : Anti-Obesity Agents
[+]

This study clearly indicates the potential of L-Theanine in counteracting the damage inflicted by aluminium on rat brain regions.Dec 31, 2014

Pubmed Data : Drug Chem Toxicol. 2015 Jan ;38(1):22-31. Epub 2014 Mar 24. PMID: 24654859
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Aluminum Toxicity , Lipid Peroxidation, Neurodegenerative Diseases, Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Through its powerful antioxidative properties, L-theanine ameliorates vincristine-induced neuropathy.Mar 24, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2023 Mar 25 ;12(4). Epub 2023 Mar 25. PMID: 37107178
Article Published Date : Mar 24, 2023
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

L-Theanine affects intestinal mucosal immunity by regulating short-chain fatty acid metabolism under dietary fiber feeding.Sep 22, 2020

Pubmed Data : Food Funct. 2020 Sep 23 ;11(9):8369-8379. PMID: 32935679
Article Published Date : Sep 22, 2020
Study Type : In Vitro Study
Additional Links
Substances : Theanine
Pharmacological Actions : Immunomodulatory
[+]

L-theanine alleviates IMQ-induced psoriasis like skin inflammation.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2021 ;12:719842. Epub 2021 Jul 26. PMID: 34381369
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Theanine
Diseases : Psoriasis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-23 Downregulation, NF-kappaB Inhibitor
[+]

L-theanine and caffeine have clear beneficial effects on sustained attention, memory, and suppression of distraction.Jan 04, 2017

Pubmed Data : Curr Pharm Des. 2017 Jan 5. Epub 2017 Jan 5. PMID: 28056735
Article Published Date : Jan 04, 2017
Study Type : Review
Additional Links
Substances : Caffeine, Theanine
Diseases : Cognitive Decline/Dysfunction, Memory Disorders
Pharmacological Actions : Neuroprotective Agents
[+]

l-Theanine attenuates liver aging by inhibiting advanced glycation end products.Feb 29, 2020

Pubmed Data : Exp Gerontol. 2020 Mar ;131:110823. Epub 2019 Dec 31. PMID: 31899338
Article Published Date : Feb 29, 2020
Study Type : In Vitro Study
Additional Links
Substances : Theanine
Diseases : Advanced Glycation End products (AGE), Aging: Liver, Liver Damage
Pharmacological Actions : Anti-Glycation Agents, Anti-Inflammatory Agents, Antioxidants
[+]

L-Theanine inhibits melanoma cell growth and migration.Sep 19, 2021

Pubmed Data : Eur J Nutr. 2021 Sep 20. Epub 2021 Sep 20. PMID: 34542664
Article Published Date : Sep 19, 2021
Study Type : In Vitro Study
Additional Links
Substances : Theanine
Diseases : Melanoma
Pharmacological Actions : Antiproliferative
Additional Keywords : Gene Expression Regulation
[+]

L-theanine provides neuroprotection against Parkinson's disease related pesticide neurotoxicants. Jul 01, 2008

Pubmed Data : Neurotoxicology. 2008 Jul;29(4):656-62. Epub 2008 Mar 20. PMID: 18452993
Article Published Date : Jul 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Theanine
Diseases : Parkinson's Disease, Pesticide Toxicity
Pharmacological Actions : Neuroprotective Agents
[+]

Neuroprotective attributes of L-theanine, a bioactive amino acid of tea, and its potential role in Parkinson's disease therapeutics.May 26, 2019

Pubmed Data : Neurochem Int. 2019 May 27:104478. Epub 2019 May 27. PMID: 31145971
Article Published Date : May 26, 2019
Study Type : In Vitro Study
Additional Links
Substances : Theanine
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Protective effects of L-theanine on IPEC-J2 cells growth inhibition induced by dextran sulfate sodium.Nov 18, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2021 Nov 19 ;26(22). Epub 2021 Nov 19. PMID: 34834090
Article Published Date : Nov 18, 2021
Study Type : In Vitro Study
Additional Links
Substances : Theanine
Pharmacological Actions : Cytoprotective
[+]

Supplementation of L-theanine may assist in the reduction of stress and anxiety in people exposed to stressful conditions.Nov 21, 2019

Pubmed Data : Plant Foods Hum Nutr. 2019 Nov 22. Epub 2019 Nov 22. PMID: 31758301
Article Published Date : Nov 21, 2019
Study Type : Review
Additional Links
Substances : Green Tea, Theanine
Diseases : Anxiety
Pharmacological Actions : Anti-Anxiety Agents
[+]

Synergistic effects of epigallocatechin gallate and l-theanine in nerve repair and regeneration.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2022 ;9:951415. Epub 2022 Aug 10. PMID: 36034895
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate), Theanine
Diseases : Alzheimer's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Nerve Regeneration
[+]

Synergistic effects of L-theanine and epigallocatechin gallate in alleviating ovalbumin allergy.Feb 20, 2023

Pubmed Data : Food Funct. 2023 Feb 21 ;14(4):2059-2073. Epub 2023 Feb 21. PMID: 36727615
Article Published Date : Feb 20, 2023
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate), Theanine
Diseases : Food Allergies
Pharmacological Actions : Immunomodulatory
Additional Keywords : Natural Substance Synergy
[+]

Theanine enhances the antitumor efficacy of chemotherapeutic agents. Dec 05, 2003

Pubmed Data : Biochim Biophys Acta. 2003 Dec 5;1653(2):47-59. PMID: 14643924
Article Published Date : Dec 05, 2003
Study Type : Review
Additional Links
Substances : Theanine
Diseases : Cancers: All, Ovarian Cancer
Pharmacological Actions : Antineoplastic Agents, Enzyme Inhibitors
Additional Keywords : Drug: Doxorubicin, Drug-Plant-Vitamin Synergies
[+]

Theanine inhibits the growth of leukemia and non-small cell lung cancer cells and enhances the anticancer activity of anticancer drugs. Apr 01, 2009

Pubmed Data : Cytotechnology. 2009 Apr;59(3):211-7. Epub 2009 Sep 17. PMID: 19760127
Article Published Date : Apr 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Theanine
Diseases : Leukemia, Non-Small-Cell Lung Carcinoma
Pharmacological Actions : Anti-metastatic
Additional Keywords : Drug: Norcantharidin, Drug-Plant-Vitamin Synergies
[+]

Theanine inhibits the invasion of hepatoma cells. Jul 01, 2001

Pubmed Data : Cytotechnology. 2001 Jul;36(1-3):195-200. PMID: 19003331
Article Published Date : Jul 01, 2001
Study Type : In Vitro Study
Additional Links
Substances : Theanine
Diseases : Cancer Metastasis, Hepatoma
Pharmacological Actions : Anti-metastatic
[+]

Theanine prevents stress-induced brain atrophy by modifying early stress responses.Jan 07, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Jan 8 ;12(1). Epub 2020 Jan 8. PMID: 31936294
Article Published Date : Jan 07, 2020
Study Type : In Vitro Study
Additional Links
Substances : Theanine
Diseases : Stress
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Gene Expression Regulation
[+]

These findings demonstrated that the neuroprotective role of theanine was associated with its anti-oxidative, anti-inflammatory, and anti-apoptotic properties.Jan 14, 2020

Pubmed Data : Life Sci. 2020 Jan 15 ;241:117160. Epub 2019 Dec 13. PMID: 31837331
Article Published Date : Jan 14, 2020
Study Type : In Vitro Study
Additional Links
Substances : Theanine
Diseases : Brain Ischemia, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

These observations suggested that theanine exerted potent cytotoxicity on tumor cells when glutamine was restricted.Oct 31, 2018

Pubmed Data : Mol Med Rep. 2018 Nov ;18(5):4535-4542. Epub 2018 Sep 5. PMID: 30221698
Article Published Date : Oct 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Theanine
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic

Copyright: radiantskies / 123RF Stock Photo

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