Thymol

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37 Diseases Researched for Thymol
NameACCKFocus
Alzheimer's Disease36Locked
High Fat Diet36Locked
Lipopolysaccharide-Induced Toxicity35Locked
Candida Albicans23Locked
Inflammation23Locked
Lung Injury: Acute23Locked
Obesity23Locked
Brain Inflammation 12Locked
Brain: Oxidative Stress12Locked
Chemically-Induced Liver Damage12Locked
Chemotherapy and Radiation Toxicity12Locked
Cognitive Decline/Dysfunction12Locked
Diabetes: Cataract12Locked
Diabetic Complications12Locked
Diabetic Nephropathy12Locked
Endometritis12Locked
Insulin Resistance12Locked
Mitochondrial Dysfunction 12Locked
Myocardial Infarction12Locked
Oxidative Stress12Locked
Toxoplasma gondii Infection12Locked
Toxoplasmosis12Locked
Acetaminophen (Tylenol) Toxicity 11Locked
Bladder Cancer11Locked
Clostridium Infections11Locked
Colorectal Cancer11Locked
DNA damage11Locked
Dental Caries11Locked
Foodborne Pathogens: Prevention/Food Preservation11Locked
Gram-Negative Bacterial Infections11Locked
Herpes Simplex Virus Type 111Locked
Prostate Cancer11Locked
Pseudomonas aeruginosa11Locked
Radiation Induced Illness11Locked
Respiratory Tract Infections11Locked
Staphylococcus aureus infection11Locked
Steptococcus Mutans Infections11Locked
26 Pharmacological Actions Researched for Thymol
NameACCKFocus
Antioxidants813Locked
Anti-Inflammatory Agents57Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor47Locked
Neuroprotective Agents36Locked
Interleukin-1 beta downregulation35Locked
Antimicrobial33Locked
Heme oxygenase-1 up-regulation23Locked
Hepatoprotective23Locked
Interleukin-6 Downregulation23Locked
Nrf2 activation23Locked
Radioprotective23Locked
Anti-Bacterial Agents22Locked
Antifungal Agents12Locked
Antiparasitic Agents12Locked
Cyclooxygenase 2 Inhibitors12Locked
Cytotoxicity22Locked
NF-kappaB Inhibitor12Locked
Renoprotective12Locked
Vascular Endothelial Growth Factor Inhibitors12Locked
Antiproliferative 11Locked
Antiviral Agents11Locked
Apoptotic11Locked
Cardioprotective11Locked
Cell cycle arrest11Locked
Genoprotective11Locked
Immunomodulatory11Locked

View the Evidence:
65 Abstracts with Thymol Research

[+]

Cardioprotective effect of thymol against adrenaline-induced myocardial injury in rats.Jun 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Heliyon. 2020 Jul ;6(7):e04431. Epub 2020 Jul 21. PMID: 32715125
Article Published Date : Jun 30, 2020
Study Type : Animal Study
Additional Links
Substances : Thymol
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Interleukin-1 beta downregulation, Malondialdehyde Down-regulation, NF-kappaB Inhibitor
[+]

Administration of thymol afforded remarkable protection against high fat diet induced diabetic nephropathy.Feb 04, 2016

Pubmed Data : Chem Biol Interact. 2016 Feb 5 ;245:1-11. Epub 2015 Dec 8. PMID: 26680107
Article Published Date : Feb 04, 2016
Study Type : Animal Study
Additional Links
Substances : Thymol
Diseases : Diabetic Nephropathy, High Fat Diet
Pharmacological Actions : Renoprotective, Vascular Endothelial Growth Factor Inhibitors
[+]

Both hesperidin and thymol were effective in suppressing allergic symptoms and inflammation in the treatment of allergic rhinitis.Nov 27, 2018

Pubmed Data : Eur Arch Otorhinolaryngol. 2018 Nov 28. Epub 2018 Nov 28. PMID: 30488351
Article Published Date : Nov 27, 2018
Study Type : Animal Study
Additional Links
Substances : Hesperidin, Thymol
Diseases : Allergic Rhinitis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Cognitive-enhancing activity of thymol and carvacrol in two rat models of dementia.May 31, 2012

Pubmed Data : Behav Pharmacol. 2012 Jun ;23(3):241-9. PMID: 22470103
Article Published Date : May 31, 2012
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Alzheimer's Disease, Dementia
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cholinesterase Inhibitors
[+]

Estragole and thymol display important anti-Toxoplasma activity.Feb 01, 2016

Pubmed Data : J Parasitol. 2016 Feb 2. Epub 2016 Feb 2. PMID: 26836848
Article Published Date : Feb 01, 2016
Study Type : Animal Study
Additional Links
Substances : Thymol
Diseases : Toxoplasma gondii Infection, Toxoplasmosis
Pharmacological Actions : Antiparasitic Agents
[+]

Evaluation of the antibacterial activity and efflux pump reversal of thymol and carvacrol against Staphylococcus aureus.Apr 29, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Apr 30 ;25(9). Epub 2020 Apr 30. PMID: 32365898
Article Published Date : Apr 29, 2020
Study Type : Insect Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents
[+]

Gastroprotective effects of oleuropein and thymol on indomethacin-induced gastric ulcerNov 13, 2018

Pubmed Data : Drug Chem Toxicol. 2018 Nov 14:1-13. Epub 2018 Nov 14. PMID: 30426792
Article Published Date : Nov 13, 2018
Study Type : Animal Study
Additional Links
Substances : Oleuropein, Thymol
Diseases : Drug-Induced Toxicity: Indomethacin, Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Gastroprotective
Problem Substances : Indomethacin
[+]

Hepatoprotective role of thymol in drug-induced gastric ulcer model.Oct 15, 2018

Pubmed Data : Ann Hepatol. 2018 Oct 16 ;17(6):980-991. PMID: 30600301
Article Published Date : Oct 15, 2018
Study Type : Animal Study
Additional Links
Substances : Thymol
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents
[+]

In vitro data demonstrated concentration-dependent thymol inhibition of both C. albicans growth and biofilm formation.Jan 18, 2016

Pubmed Data : Immunol Res. 2016 Jan 19. Epub 2016 Jan 19. PMID: 26783030
Article Published Date : Jan 18, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Thymol
Diseases : Candida Albicans
Pharmacological Actions : Antifungal Agents
[+]

The present study showed protective effects of thymol in rotenone-induced neurotoxicity and neurodegeneration.Mar 26, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Mar 27 ;20(7). Epub 2019 Mar 27. PMID: 30934738
Article Published Date : Mar 26, 2019
Study Type : Animal Study
Additional Links
Substances : Thymol
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

The Zataria multiflora extract had a potent bactericidal effect against A. baumannii that could downregulate the ompA gene.Jul 23, 2019

Pubmed Data : J Cell Biochem. 2019 Jul 24. Epub 2019 Jul 24. PMID: 31338900
Article Published Date : Jul 23, 2019
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Thymol, Zataria multiflora
Diseases : Acinetobacter baumannii infection
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Gene Expression
[+]

This study clearly documents the antioxidant, anticlastogenic and radioprotective potentials of thymol.Dec 23, 2011

Pubmed Data : Mutat Res. 2011 Dec 24 ;726(2):136-45. Epub 2011 Sep 14. PMID: 21933721
Article Published Date : Dec 23, 2011
Study Type : Animal Study
Additional Links
Substances : Thymol
Diseases : Lipid Peroxidation, Radiation Induced Illness
Pharmacological Actions : Antimutagenic Agents, Antioxidants, Radioprotective
[+]

Thymol and carvacrol are highly promising candidates for the development of effective and safe drugs in the fight against visceral leishmaniasis.May 29, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 May 30 ;24(11). Epub 2019 May 30. PMID: 31151304
Article Published Date : May 29, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Leishmaniasis
Pharmacological Actions : Leishmanicidal
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Thymol can be therapeutic against high risk factors for Alzheimer's disease.Jan 12, 2018

Pubmed Data : Brain Res Bull. 2018 Jan 13 ;137:338-350. Epub 2018 Jan 13. PMID: 29339105
Article Published Date : Jan 12, 2018
Study Type : Animal Study
Additional Links
Substances : Thymol
Diseases : Alzheimer's Disease, Brain: Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Thymol decreased the effects of Aβ on memory and could be considered as neuroprotective.Mar 01, 2017

Pubmed Data : Metab Brain Dis. 2017 Mar 2. Epub 2017 Mar 2. PMID: 28255862
Article Published Date : Mar 01, 2017
Study Type : Animal Study
Additional Links
Substances : Thymol
Diseases : Alzheimer's Disease, High Fat Diet, Obesity
Pharmacological Actions : Neuroprotective Agents
[+]

Thymol effectively protects against nano titanium dioxide-induced hepatotoxicity in rats by its antioxidant properties.Dec 16, 2017

Pubmed Data : Environ Toxicol Pharmacol. 2017 Dec 17 ;58:29-36. Epub 2017 Dec 17. PMID: 29289817
Article Published Date : Dec 16, 2017
Study Type : Animal Study
Additional Links
Substances : Thymol
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Hepatoprotective
Problem Substances : Titanium Nanoparticles
[+]

Thymol exhibited beneficial effects on HFD-induced cognitive deficits through improving hippocampal insulin resistance.Oct 19, 2016

Pubmed Data : Metab Brain Dis. 2016 Oct 20. Epub 2016 Oct 20. PMID: 27761760
Article Published Date : Oct 19, 2016
Study Type : Animal Study
Additional Links
Substances : Thymol
Diseases : Cognitive Decline/Dysfunction, High Fat Diet, Insulin Resistance
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
[+]

Thymol has beneficial effects on diabetic complications.Aug 12, 2018

Pubmed Data : Drug Res (Stuttg). 2018 Aug 13. Epub 2018 Aug 13. PMID: 30103218
Article Published Date : Aug 12, 2018
Study Type : Animal Study
Additional Links
Substances : Thymol
Diseases : Diabetic Complications
Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Hypolipidemic
[+]

Thymol improves barrier function and attenuates inflammatory responses in intestinal epithelial cells during lipopolysaccharide induced inflammation.Dec 18, 2018

Pubmed Data : J Agric Food Chem. 2018 Dec 19. Epub 2018 Dec 19. PMID: 30567427
Article Published Date : Dec 18, 2018
Study Type : Animal Study
Additional Links
Substances : Thymol
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Thymol inhibits biofilm formation, eliminates pre-existing biofilms, and enhances clearance of methicillin-resistant Staphylococcus aureus.Jan 09, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Microorganisms. 2020 Jan 10 ;8(1). Epub 2020 Jan 10. PMID: 31936809
Article Published Date : Jan 09, 2020
Study Type : Animal Study
Additional Links
Substances : Thymol
Diseases : Staphylococcus aureus: Methicillin-resistant (MRSA)
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation
[+]

Thymol isolated from Thymus vulgaris L. inhibits colorectal cancer cell growth and metastasis.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2020 ;14:2535-2547. Epub 2020 Jul 1. PMID: 32669835
Article Published Date : Dec 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Thymol
Diseases : Colorectal Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Wnt/β-catenin signaling pathway modulation
[+]

Thymol may be a potential therapeutic approach in the prevention of diabetic complications.Sep 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharm Bioallied Sci. 2016 Oct-Dec;8(4):277-283. PMID: 28216950
Article Published Date : Sep 30, 2016
Study Type : Animal Study
Additional Links
Substances : Thymol
Diseases : Diabetes: Cataract, Diabetic Complications
Pharmacological Actions : Antioxidants
[+]

Thymol might be useful in the therapy of acute lung injury.Oct 09, 2017

Pubmed Data : Inflammation. 2017 Oct 10. Epub 2017 Oct 10. PMID: 29019091
Article Published Date : Oct 09, 2017
Study Type : Animal Study
Additional Links
Substances : Thymol
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Thymol mitigates lipopolysaccharide-induced endometritis.Mar 20, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Mar 21 ;8(12):20042-20055. PMID: 28223539
Article Published Date : Mar 20, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Thymol
Diseases : Endometritis, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Antioxidants, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Thymol pre and co-treatment showed near normalized effects on all the biochemical parameters studied.Jan 24, 2016

Pubmed Data : Chem Biol Interact. 2016 Jan 25 ;244:159-68. Epub 2015 Dec 22. PMID: 26721194
Article Published Date : Jan 24, 2016
Study Type : Animal Study
Additional Links
Substances : Thymol
Diseases : Mitochondrial Dysfunction , Myocardial Infarction, Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Thymol significantly protected acute and chronic salivary gland dysfunction induced by ionizing radiation in the rats.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Pharm Res. 2016 ;15(4):861-866. PMID: 28243283
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Thymol
Diseases : Chemotherapy and Radiation Toxicity
Pharmacological Actions : Radioprotective
Anti Therapeutic Actions : Low Dose Ionizing Radiation
[+]

Thymoquinone alleviates the experimentally induced Alzheimer's disease inflammation.Dec 31, 2017

Pubmed Data : Hum Exp Toxicol. 2018 Jan 1:960327118755256. Epub 2018 Jan 1. PMID: 29405769
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Thymol
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

A review of the anti-cancer activity of thymol.Oct 10, 2018

Pubmed Data : IUBMB Life. 2018 Oct 11. Epub 2018 Oct 11. PMID: 30308112
Article Published Date : Oct 10, 2018
Study Type : Review
Additional Links
Substances : Thymol
Diseases : Cancers: All
Pharmacological Actions : Chemotherapeutic
[+]

An in-depth view of potential dual effect of thymol in inhibiting xanthine oxidase activity.Aug 06, 2018

Pubmed Data : Int J Biol Macromol. 2018 Aug 7. Epub 2018 Aug 7. PMID: 30096398
Article Published Date : Aug 06, 2018
Study Type : In Vitro Study
Additional Links
Substances : Thymol
Diseases : Cancers: All, Gout, Hyperuricemia
Pharmacological Actions : Xanthine oxidase inhibitor
[+]

Anti-biofilm activities of essential oils rich in carvacrol and thymol against Salmonella Enteritidis.Feb 28, 2019

Pubmed Data : Biofouling. 2019 Mar ;35(3):361-375. Epub 2019 May 14. PMID: 31088182
Article Published Date : Feb 28, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Salmonella Infections
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation, Essential Oils
[+]

Antifungal activity of thymol and carvacrol against postharvest pathogens Botrytis cinerea.Apr 30, 2019

Pubmed Data : J Food Sci Technol. 2019 May ;56(5):2611-2620. Epub 2019 Apr 15. PMID: 31168143
Article Published Date : Apr 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Pharmacological Actions : Antifungal Agents
Additional Keywords : Plant Disease
[+]

Antioxidant efficacy of thymol and carvacrol in microencapsulated walnut oil triacylglycerols.Apr 24, 2019

Pubmed Data : Food Chem. 2019 Apr 25 ;278:805-810. Epub 2018 Dec 4. PMID: 30583446
Article Published Date : Apr 24, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol, Walnut
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Oils
[+]

Carvacrol and thymol inhibit biofilm formation of carbapenemase-producing gram negative bacilli strains.May 19, 2017

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2017 May 20 ;63(5):108-112. Epub 2017 May 20. PMID: 28719354
Article Published Date : May 19, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Gram-Negative Bacterial Infections
Pharmacological Actions : Antimicrobial
Additional Keywords : Biofilm
[+]

Carvacrol and thymol isolated from O. vulgare L. exhibit good bactericidal and antibiofilm activity against S. mutans.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : AMB Express. 2017 Dec ;7(1):49. Epub 2017 Feb 23. PMID: 28233286
Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Oregano, Thymol
Diseases : Dental Caries, Steptococcus Mutans Infections
Pharmacological Actions : Antimicrobial
Additional Keywords : Biofilm
[+]

Carvacrol, cinnamaldehyde, thymol, or oregano oil inhibit Clostridum prefringens in beef.Jul 01, 2006

Pubmed Data : J Food Prot. 2006 Jul;69(7):1546-51. PMID: 16865884
Article Published Date : Jul 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Cinnamaldehyde, Cinnamon, Oregano, Thyme, Thymol
Diseases : Clostridium Infections
Pharmacological Actions : Anti-Bacterial Agents
[+]

Combination of carvacrol and thymol has antimicrobial activity against Staphylococcus aureus and antioxidant activity.Apr 18, 2019

Pubmed Data : Foodborne Pathog Dis. 2019 Apr 19. Epub 2019 Apr 19. PMID: 31009261
Article Published Date : Apr 18, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Staphylococcus aureus infection
Pharmacological Actions : Antimicrobial
[+]

Computational evaluation of major components from plant essential oils as potent inhibitors of SARS-CoV-2 spike protein.Dec 04, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Mol Struct. 2020 Dec 5 ;1221:128823. Epub 2020 Jul 4. PMID: 32834111
Article Published Date : Dec 04, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Cinnamaldehyde, Geraniol , Thymol
Diseases : Coronavirus Infection
Pharmacological Actions : Antiviral Agents
Additional Keywords : Essential Oils
[+]

Effects of carvacrol, thymol and essential oils containing such monoterpenes on wound healing: a systematic review.Jan 31, 2019

Pubmed Data : J Pharm Pharmacol. 2019 Feb ;71(2):141-155. Epub 2018 Dec 7. PMID: 30537169
Article Published Date : Jan 31, 2019
Study Type : Review
Additional Links
Substances : Carvacrol, Thymol
Diseases : Oxidative Stress, Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Essential Oils
[+]

Effects of thymol on human gastric adenocarcinoma cells in vitro.Feb 23, 2018

Pubmed Data : Altern Ther Health Med. 2018 Feb 24. Epub 2018 Feb 24. PMID: 29477139
Article Published Date : Feb 23, 2018
Study Type : In Vitro Study
Additional Links
Substances : Thymol
Diseases : Gastric Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Apoptotic, gastric cancer, Thymol
[+]

Eugenol and thymol, alone or in combination, induce morphological alterations in the envelope of Candida albicans.Aug 31, 2007

Pubmed Data : Fitoterapia. 2007 Sep ;78(6):396-400. Epub 2007 May 23. PMID: 17590533
Article Published Date : Aug 31, 2007
Study Type : In Vitro Study
Additional Links
Substances : Eugenol, Thymol
Diseases : Candida Albicans
Pharmacological Actions : Antifungal Agents
Additional Keywords : Natural Substance Synergy
[+]

Extracts of thyme and primrose with the addition of thymol was comparable to synthetic ambroxol.Dec 31, 2015

Pubmed Data : Wiad Lek. 2016 ;69(6):791-798. PMID: 28214817
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Evening Primrose Oil, Thyme, Thymol
Diseases : Respiratory Tract Infections
Pharmacological Actions : Anti-Inflammatory Agents, Antimicrobial, Antioxidants
Additional Keywords : Natural Substances Versus Drugs
[+]

In vitro anti-biofilm activities of citral and thymol against candida tropicalis.Feb 02, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Fungi (Basel). 2019 Feb 3 ;5(1). Epub 2019 Feb 3. PMID: 30717454
Article Published Date : Feb 02, 2019
Study Type : In Vitro Study
Additional Links
Substances : Citral, Thymol
Diseases : Candida Infection
Pharmacological Actions : Antifungal Agents
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation
[+]

Inhibitory effects of thymol on the cytotoxicity and inflammatory responses induced by Staphylococcus aureus extracellular vesicles.Jun 17, 2019

Pubmed Data : Microb Pathog. 2019 Jun 18 ;134:103603. Epub 2019 Jun 18. PMID: 31226290
Article Published Date : Jun 17, 2019
Study Type : In Vitro Study
Additional Links
Substances : Thymol
Diseases : Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents
Additional Keywords : Exosomes
[+]

Potentiating the activity of berberine for Staphylococcus aureus in a combinatorial treatment with thymol.Sep 29, 2020

Pubmed Data : Microb Pathog. 2020 Sep 30 ;149:104542. Epub 2020 Sep 30. PMID: 33010366
Article Published Date : Sep 29, 2020
Study Type : In Vitro Study
Additional Links
Substances : Berberine, Thymol
Diseases : Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Natural Substance Synergy
[+]

Studies with fresh meat, meat products, fish, milk, dairy products and cooked rice have shown that the concentration of essential oils needed to achieve a significant antibacterial effect is around 0.5 microl g (-1) in foods and about .1 - 10 microl ml (-Aug 01, 2004

Pubmed Data : Int J Food Microbiol. 2004 Aug 1 ;94(3):223-53. PMID: 15246235
Article Published Date : Aug 01, 2004
Study Type : Bacterial
Additional Links
Substances : Carvacrol, Cinnamaldehyde, Cinnamic acid, Eugenol, Perillaldehyde, Thymol
Diseases : Foodborne Pathogens: Prevention/Food Preservation
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Food Preservation With Essential Oils
[+]

The antibacterial mechanism of carvacrol and thymol against Escherichia coli.Aug 31, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lett Appl Microbiol. 2008 Sep ;47(3):174-9. PMID: 19552781
Article Published Date : Aug 31, 2008
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Escherichia coli Infections
Pharmacological Actions : Anti-Bacterial Agents
[+]

These results confirm that thymol may have antiproliferative potential against brain tumor cells involving oxidative alteration.Dec 31, 2016

Pubmed Data : Cent Nerv Syst Agents Med Chem. 2017 ;17(2):116-122. PMID: 27554922
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Thymol
Diseases : Brain Cancer
Pharmacological Actions : Antioxidants, Antiproliferative
[+]

This study provided the evidence regarding the protective effects of carvacrol and thymol against Aβ25–35-induced cytotoxicity in PC12 cells.Dec 31, 2019

Pubmed Data : Iran Biomed J. 2020 07 ;24(4):243-50. Epub 2020 Jan 22. PMID: 32306722
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Thymol ameliorates inflammatory response and accelerates regeneration in cardiotoxin-induced muscle injury.Jan 27, 2016

Pubmed Data : J Pharm Pharmacol. 2016 Jan 28. Epub 2016 Jan 28. PMID: 26817998
Article Published Date : Jan 27, 2016
Study Type : In Vitro Study
Additional Links
Substances : Thymol
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective
[+]

Thymol and carvacrol downregulate the expression of Salmonella typhimurium virulence genes.Jun 06, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Microorganisms. 2020 Jun 7 ;8(6). Epub 2020 Jun 7. PMID: 32517327
Article Published Date : Jun 06, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Salmonella Infections
Pharmacological Actions : Anti-Bacterial Agents
[+]

Thymol and carvacrol protected against acetaminophen induced toxicity.Jan 21, 2016

Pubmed Data : Hum Exp Toxicol. 2016 Jan 22. Epub 2016 Jan 22. PMID: 26801986
Article Published Date : Jan 21, 2016
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Acetaminophen (Tylenol) Toxicity
Pharmacological Actions : Antioxidants, Hepatoprotective
Additional Keywords : Dose Response
Problem Substances : Acetaminophen, Paracetamol
[+]

Thymol as a reciprocal regulator of T cell differentiation: Promotion of regulatory T cells and suppression of Th1/Th17 cells.Jan 31, 2019

Pubmed Data : Int Immunopharmacol. 2019 Feb ;67:417-426. Epub 2018 Dec 31. PMID: 30586665
Article Published Date : Jan 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Thymol
Diseases : Immune Dysregulation: TH17 over-expression, Immune Dysregulation: TH1 dominance
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Thymol at low concentrations provides antioxidative protection to WS-1 cells, while already inducing toxic effects in gastric adenocarcinoma cells.Jul 16, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Jul 17 ;25(14). Epub 2020 Jul 17. PMID: 32709059
Article Published Date : Jul 16, 2020
Study Type : In Vitro Study
Additional Links
Substances : Thymol
Diseases : Gastric Cancer
Pharmacological Actions : Antioxidants, Antiproliferative , Apoptotic
[+]

Thymol could be a useful therapeutic agent for the prevention of bone destructive diseases.Jul 22, 2018

Pubmed Data : Food Chem Toxicol. 2018 Jul 23 ;120:418-429. Epub 2018 Jul 23. PMID: 30048646
Article Published Date : Jul 22, 2018
Study Type : In Vitro Study
Additional Links
Substances : Thymol
Diseases : Osteoporosis
Pharmacological Actions : Matrix metalloproteinase-9 (MMP-9) inhibitor, Osteoprotective
[+]

Thymol elicits HCT-116 colorectal carcinoma cell death through induction of oxidative stress.Mar 26, 2017

Pubmed Data : Anticancer Agents Med Chem. 2017 Mar 27. Epub 2017 Mar 27. PMID: 28356011
Article Published Date : Mar 26, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymol
Diseases : Colorectal Cancer
Pharmacological Actions : Cytotoxicity
[+]

Thymol had anti-inflammatory and anti-oxidative effects against LPS-induced acute lung injury.Dec 24, 2017

Pubmed Data : Microb Pathog. 2017 Dec 25 ;116:8-12. Epub 2017 Dec 25. PMID: 29284133
Article Published Date : Dec 24, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymol
Diseases : Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Thymol induced Ca²⁺-dissociated cell death in prostate cancer.Jan 27, 2017

Pubmed Data : Chin J Physiol. 2017 02 28 ;60(1):32-40. PMID: 28052644
Article Published Date : Jan 27, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymol
Diseases : Prostate Cancer
Pharmacological Actions : Cytotoxicity
[+]

Thymol induces conidial apoptosis in Aspergillus flavus. Aug 14, 2018

Pubmed Data : J Agric Food Chem. 2018 Aug 15 ;66(32):8530-8536. Epub 2018 Aug 6. PMID: 30044621
Article Published Date : Aug 14, 2018
Study Type : In Vitro Study
Additional Links
Substances : Thymol
Diseases : Fungal Infection
Pharmacological Actions : Antifungal Agents
[+]

Thymol induces mitochondrial pathway-mediated apoptosis via ROS generation, macromolecular damage and SOD diminution in A549 cells.Oct 22, 2020

Pubmed Data : Pharmacol Rep. 2020 Oct 23. Epub 2020 Oct 23. PMID: 33095436
Article Published Date : Oct 22, 2020
Study Type : In Vitro Study
Additional Links
Substances : Thymol
Diseases : Carcinoma: Non-Small-Cell Lung
Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Cell cycle arrest
[+]

Thymol inhibits bladder cancer cell proliferation via inducing cell cycle arrest and apoptosis.Apr 03, 2017

Pubmed Data : Biochem Biophys Res Commun. 2017 Apr 4. Epub 2017 Apr 4. PMID: 28389245
Article Published Date : Apr 03, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymol
Diseases : Bladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Thymol may be explored as a potentially promising food additive for prevention of obesity.Jul 17, 2016

Pubmed Data : Eur J Nutr. 2016 Jul 18. Epub 2016 Jul 18. PMID: 27431894
Article Published Date : Jul 17, 2016
Study Type : In Vitro Study
Additional Links
Substances : Thymol
Diseases : Obesity
Additional Keywords : Anti-Obesity Agents, Gene Expression Regulation
[+]

Thymol mediates bactericidal activity against Staphylococcus aureus by targeting an aldo-keto reductase and consequent depletion of NADPH.Jul 30, 2019

Pubmed Data : J Agric Food Chem. 2019 Jul 31 ;67(30):8382-8392. Epub 2019 Jul 17. PMID: 31271032
Article Published Date : Jul 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Thymol
Diseases : Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents
[+]

Thymol seems to be a promising candidate for topical therapeutic application as antiviral agent for treatment of herpetic infections.Aug 29, 2017

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2017 Aug 30 ;63(8):42-47. Epub 2017 Aug 30. PMID: 28886313
Article Published Date : Aug 29, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Herpes Simplex Virus Type 1
Pharmacological Actions : Antiviral Agents
Additional Keywords : Essential Oils
[+]

Thymol, a major constituent of thyme, protects against gamma ray-induced genotoxicity. Aug 01, 1992

Pubmed Data : J Dairy Sci. 1992 Aug;75(8):2205-14. PMID: 21147817
Article Published Date : Aug 01, 1992
Study Type : In Vitro Study
Additional Links
Substances : Thyme, Thymol
Diseases : DNA damage, Radiation Induced Illness
Pharmacological Actions : Genoprotective, Radioprotective
[+]

Thymus vulgaris and thymol assist murine macrophages in the control of in vitro infections.Jul 31, 2017

Pubmed Data : Immunol Res. 2017 Aug ;65(4):932-943. PMID: 28752199
Article Published Date : Jul 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thyme, Thymol
Diseases : Candida Albicans, Pseudomonas aeruginosa, Staphylococcus aureus infection
Pharmacological Actions : Immunomodulatory

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