Tocopherols

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31 Diseases Researched for Tocopherols

Name	AC	CK
Oxidative Stress	5	28
C-Reactive Protein	1	20
Breast Cancer	6	15
Prostate Cancer	5	12
Arterial Hardening: Elasticity	1	10
DNA damage	1	10
Diabetes Mellitus: Type 2	1	10
Endothelial Dysfunction	1	10
Head and Neck Cancer	1	10
Hyperglycemia	1	10
Nonalcoholic fatty liver disease (NAFLD)	1	10
Skin Cancer	1	10
Colon Cancer	3	8
Cancer: Prostate	1	5
Cancers: All	2	4
Esophageal Cancer	1	4
Atherosclerosis	2	2
Breast Cancer: estrogen receptor alpha-positive	1	2
Colitis	1	2
Colon Cancer: Prevention	1	2
High Fat Diet	1	2
Infertility: Male	1	2
Lipid Peroxidation	1	2
Cardiovascular Diseases	1	1
Chemotherapy-Induced Toxicity: Cyclophosphamide	1	1
Chemotherapy-Induced Toxicity: Doxorubicin	1	1
Mastocytoma	1	1
Nasopharyngeal Cancer	1	1
Ovarian Cancer	1	1
Pancreatic Cancer	1	1
Photooxidative Stress	1	1

19 Pharmacological Actions Researched for Tocopherols

Name	AC	CK
Chemopreventive	16	47
Antioxidants	9	35
Antiproliferative	8	21
Anticarcinogenic Agents	6	20
Malondialdehyde Down-regulation	2	20
Anti-Inflammatory Agents	4	18
Apoptotic	5	11
Hepatoprotective	1	10
Hypoglycemic Agents	1	10
Enzyme Inhibitors	1	5
NF-kappaB Inhibitor	2	5
Cell cycle arrest	3	4
Chemotherapeutic	2	2
Fertility Agents: Male	1	2
Gastrointestinal Agents	1	2
Nrf2 activation	1	2
Anti-atherogenic	1	1
Multidrug Resistance Gene Modulators	1	1
Photoprotective	1	1

Research Articles 38
Cumulative Knowledge Score 61
Overall Research Rating GOOD

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38 Abstracts with Tocopherols Research

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The Following are Sub-Topics of Tocopherols

View the Evidence: 38 Abstracts with Tocopherols Research

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The results of this meta-analysis suggest that supplementation with vitamin E in the form of either α-tocopherol or γ-tocopherol would reduce serum CRP levels.Feb 10, 2015

Assessment of oxidative stress in tumors and histologically normal mucosa from patients with head and neck squamous cell carcinoma: a preliminary study.Mar 11, 2013

Delta-tocotrienol might be considered as an effective dietary supplement to prevent long-term diabetic complications.Apr 24, 2021

Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease.Jul 31, 2020

In conclusion, use of alpha tocopherol supplements significantly reduces serum gamma tocopherol and delta tocopherols.Sep 30, 2003

Supplementation of a gamma-tocopherol-rich mixture of tocopherols in healthy men protects against vascular endothelial dysfunction.Dec 31, 2012

The balance of α- tocopherol and γ-tocopherol may be important in maintaining arterial compliance.Aug 10, 2015

The consumption of cooked whole eggs is an effective way to increase the absorption of α-tocopherol and γ-tocopherol from foods.Oct 31, 2016

There is a positive association between dietary vitamin E intake and lung function, and evidence of an inverse relationship between serum levels of γ-tocopherol and lung function.Feb 06, 2015

Tocotrienols and tocopherols reduce markers of lipid peroxidation.Jan 10, 2017

Gamma- tocopherol was superior to alpha- tocopherol in the inactivation of the Kinase Akt.Dec 31, 2012

A Combination of γ-tocopherol-rich mixture of tocopherols and ascorbic acid restores fertility in cases of tyrosine nitration-associated male infertility. Jul 12, 2020

A gamma-tocopherol-rich mixture of tocopherols inhibits colon, prostate, mammary, and lung tumorigenesis in animal models. Sep 11, 2009

Alpha and gamma-tocopherols from Rosa mosqueta may have an important role in the prevention of alterations induced by high fat diet.Aug 31, 2018

Delta and gamma tocopherol have superior cancer preventive properties compared to alpha in the prevention of estrogen-mediated mammary carcinogenesis.Nov 30, 2017

Delta and gamma tocopherols inhibit colon carcinogenesis.Mar 31, 2012

Delta tocopherol inhibits the development of prostate adenocarcinoma.Nov 06, 2017

Gamma and delta tocopherols are effective natural agents for the prevention and treatment of estrogen-mediated breast cancer.Feb 28, 2017

Gamma tocopherol could be an effective agent for the prevention and treatment of E2-induced breast cancer.Jun 29, 2015

Gamma-tocopherol may play a significant role in preventing colon cancer.Dec 31, 2001

These results indicate that γ-TmT and δ-T could be effective preventive agents of prostate cancer. Jan 31, 2016

Tocopherols inhibit esophageal carcinogenesis through attenuating NF-κB activation and CXCR3-mediated inflammation.Jun 30, 2018

Tocopherols inhibit oxidative and nitrosative stress in estrogen-induced early mammary hyperplasia.Aug 31, 2015

Vitamin E delta-tocotrienol and metabolite 13'-carboxychromanol inhibit colitis-associated colon tumorigenesis and modulate gut microbiota in mice.Dec 31, 2020

A combination of delta and gamma tocopherols significantly inhibits prostate cancer cell growth.Dec 31, 2016

A combination of vitamin E (delta-tocopherol) and resveratrol inhibit human mastocytoma cell proliferation. Sep 01, 2008

A review of the anti-atherosclerotic effects of vitamins D and E in suppression of atherogenesis.Dec 13, 2016

Dietary administration of tocopherols inhibits tumorigenesis in estrogen receptor-positive breast cancer cells.Oct 31, 2012

Different roles of tocopherols and tocotrienols in chemoprevention and treatment of prostate cancer.May 09, 2024

Gamma tocopherol reduced chemotherapeutic-induced ROS in an ovarian granulosa cell line.Jan 06, 2020

Gamma-tocotrienol reverses multidrug resistance of breast cancer cells.Feb 04, 2021

Overlapping functions of tocopherols and carotenoids are present in protection against photooxidative stress.Jan 01, 2012

Phytochemicals which inhibit cancer stem cells may prove to be promising agents for the prevention and treatment of pancreatic cancers.Jan 25, 2017

Roselle seeds are a good source of lipid-soluble antioxidants and high levels of gamma-tocopherol.Mar 31, 2007

The experimental data provide strong evidence in support of the anticancer activities of δ-tocopherol, γ-tocopherol.May 31, 2016

These results revealed a novel mechanism of delta-tocopherol in inhibiting prostate cancer cell growth, supporting its cancer preventive activity.Oct 13, 2015

This study suggests that the absence of γ-tocopherol in traditional preparations may be one reason for the lack of consistent salutary effects of vitamin E preparations in clinical trials.Aug 13, 2015

δ-Tocotrienol induces apoptosis and inhibits proliferation of nasopharyngeal carcinoma cells.May 30, 2021

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Tocopherols

View the Evidence:
38 Abstracts with Tocopherols Research