Tongkat Ali

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43 Diseases Researched for Tongkat Ali
NameACCKFocus
Testosterone: Too Low341Locked
Erectile Dysfunction434Locked
Aging220Locked
Androgen Deficiency220Locked
Sleep Disorders110Locked
Inflammation24Locked
Toxoplasma gondii Infection34Locked
Breast Cancer33Locked
Colorectal Cancer13Locked
Acetaminophen (Tylenol) Toxicity 12Locked
Diabetes Mellitus: Type 212Locked
Diabetes Mellitus: Type 2: Prevention12Locked
Infertility12Locked
Infertility: Male12Locked
Insulin Resistance12Locked
Kidney Damage: Drug-Induced12Locked
Low Libido12Locked
Low Testosterone12Locked
Lung Cancer22Locked
Nephropathy12Locked
Parasitic Intestinal Diseases12Locked
Schistosomiasis22Locked
Sexual Dysfunction12Locked
Toxoplasmosis12Locked
Bacillus Cereus infection11Locked
Bacillus subtilis infections11Locked
Breast Cancer: Triple Negative 11Locked
Candida Albicans11Locked
Carcinoma: Non-Small-Cell Lung11Locked
Common Cold11Locked
Coronavirus Infection11Locked
Dengue11Locked
Escherichia coli Infections11Locked
Liver Cancer11Locked
Malaria11Locked
Nasopharyngeal Cancer11Locked
Plasmodium Infections11Locked
Prostate Cancer11Locked
Pseudomonas aeruginosa11Locked
Shigellosis11Locked
Staphylococcus aureus infection11Locked
Steptococcus Mutans Infections11Locked
Tumors11Locked
21 Pharmacological Actions Researched for Tongkat Ali
NameACCKFocus
Immunomodulatory110Locked
Apoptotic68Locked
Antiparasitic Agents45Locked
Anti-Inflammatory Agents24Locked
Antiproliferative 44Locked
Autophagy Inhibitors13Locked
Analgesics12Locked
Antiprotozoal Agents12Locked
Antiviral Agents22Locked
Aphrodisiac 12Locked
Cyclooxygenase 2 Inhibitors12Locked
Fertility Agents: Male12Locked
NF-kappaB Inhibitor12Locked
Renoprotective12Locked
Secretagogue12Locked
Uricosuric Agents12Locked
Anti-Bacterial Agents11Locked
Anti-Tumor11Locked
Antimalarials11Locked
Antimicrobial11Locked
Cell cycle arrest11Locked

View the Evidence:
29 Abstracts with Tongkat Ali Research

[+]

This systematic review and meta-analysis of the literature supports the possible use of E. longifolia supplementation for enhancing testosterone production.Aug 03, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicina (Kaunas). 2022 Aug 4 ;58(8). Epub 2022 Aug 4. PMID: 36013514
Article Published Date : Aug 03, 2022
Study Type : Meta Analysis, Review
Additional Links
Substances : Tongkat Ali
Diseases : Testosterone: Too Low
Additional Keywords : Plant Extracts
[+]

Based on current evidence, the herbal extract of Tongkat Ali may have clinical effect on erectile function.Sep 30, 2015

Pubmed Data : Complement Ther Med. 2015 Oct ;23(5):693-8. Epub 2015 Jul 31. PMID: 26365449
Article Published Date : Sep 30, 2015
Study Type : Meta Analysis, Review
Additional Links
Substances : Tongkat Ali
Diseases : Erectile Dysfunction
Additional Keywords : Plant Extracts
[+]

Eurycoma longifolia (Tongkat Ali) enhances wakefulness during active periods but facilitates sleep during resting periods.Nov 30, 2023

Pubmed Data : Eur J Neurosci. 2023 Dec ;58(11):4298-4309. Epub 2023 Nov 15. PMID: 37968729
Article Published Date : Nov 30, 2023
Study Type : Human Study
Additional Links
Substances : Tongkat Ali
Diseases : Sleep Disorders
[+]

Exercise associated or not to the intake of Eurycoma longifolia improves strength and cardiorespiratory fitness in men with androgen deficiency.Jan 31, 2021

Pubmed Data : Complement Ther Clin Pract. 2021 Feb ;42:101301. Epub 2021 Jan 5. PMID: 33445146
Article Published Date : Jan 31, 2021
Study Type : Human Study
Additional Links
Substances : Tongkat Ali
Diseases : Androgen Deficiency
Therapeutic Actions : Exercise
[+]

Ingestion of the root water extract of Tongkat Ali enhances comprehensive immunity in both middle-aged men and women.Jan 26, 2016

Pubmed Data : Phytother Res. 2016 Jan 27. Epub 2016 Jan 27. PMID: 26816234
Article Published Date : Jan 26, 2016
Study Type : Human Study
Additional Links
Substances : Tongkat Ali
Pharmacological Actions : Immunomodulatory
Additional Keywords : Plant Extracts
[+]

Supplementation of Physta® at 200 mg was able to increase the serum total testosterone, reduce fatigue and improve the quality of life in ageing men.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Nutr Res. 2021 ;65. Epub 2021 May 19. PMID: 34262417
Article Published Date : Dec 31, 2020
Study Type : Human Study
Additional Links
Substances : Tongkat Ali
Diseases : Aging, Testosterone: Too Low
[+]

The combination of Eurycoma longifolia and concurrent training improved erectile function and increased total testosterone levels in men with ADAM.Feb 28, 2021

Pubmed Data : Maturitas. 2021 Mar ;145:78-85. Epub 2020 Dec 10. PMID: 33541567
Article Published Date : Feb 28, 2021
Study Type : Human Study
Additional Links
Substances : Tongkat Ali
Diseases : Aging, Androgen Deficiency, Erectile Dysfunction
Additional Keywords : Phytotherapy, Plant Extracts
[+]

The effect of Eurycoma Longifolia on the regulation of reproductive hormones in young males.Apr 30, 2021

Pubmed Data : Andrologia. 2021 May ;53(4):e14001. Epub 2021 Feb 9. PMID: 33559971
Article Published Date : Apr 30, 2021
Study Type : Human Study
Additional Links
Substances : Tongkat Ali
Diseases : Testosterone: Too Low
Additional Keywords : Plant Extracts
[+]

DHOK exerts anti-cancer effect through autophagy inhibition in colorectal cancer. Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Dev Biol. 2021 ;9:760022. Epub 2021 Dec 17. PMID: 34977014
Article Published Date : Dec 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Colorectal Cancer
Pharmacological Actions : Apoptotic, Autophagy Inhibitors
[+]

Active fractions from E. longifolia have potent and selective antiproliferative activity against T. gondii tachyzoites.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2012 ;17(8):9207-19. Epub 2012 Aug 2. PMID: 22858841
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Tongkat Ali
Diseases : Toxoplasma gondii Infection, Toxoplasmosis
Pharmacological Actions : Antiparasitic Agents
Additional Keywords : Plant Extracts
[+]

Eurycoma longifolia alkaloid components ameliorate hyperuricemic nephropathy.Aug 31, 2023

Pubmed Data : J Nat Med. 2023 Sep ;77(4):867-879. Epub 2023 Jul 12. PMID: 37433989
Article Published Date : Aug 31, 2023
Study Type : Animal Study
Additional Links
Substances : Tongkat Ali
Diseases : Inflammation, Nephropathy
Pharmacological Actions : Anti-Inflammatory Agents, Uricosuric Agents
[+]

Nephroprotective effect of herbal extract Eurycoma longifolia on paracetamol-induced nephrotoxicity.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:4916519. Epub 2019 May 13. PMID: 31214269
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Tongkat Ali
Diseases : Acetaminophen (Tylenol) Toxicity , Kidney Damage: Drug-Induced
Pharmacological Actions : Renoprotective
Problem Substances : Acetaminophen, Paracetamol
[+]

Serum alpha-2-HS glycoprotein was reduced in rats treated with standardized E. longifolia extract.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2015 ;6:211. Epub 2015 Sep 23. PMID: 26441666
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Tongkat Ali
Diseases : Diabetes Mellitus: Type 2, Diabetes Mellitus: Type 2: Prevention, Infertility, Insulin Resistance
Additional Keywords : Risk Reduction
[+]

These results proved the efficacy of quassinoids on increasing sperm count in rats.Apr 21, 2016

Pubmed Data : J Ethnopharmacol. 2016 Apr 22 ;182:80-9. Epub 2016 Feb 16. PMID: 26899442
Article Published Date : Apr 21, 2016
Study Type : Animal Study
Additional Links
Substances : Tongkat Ali
Diseases : Infertility: Male
Pharmacological Actions : Fertility Agents: Male
Additional Keywords : Plant Extracts
[+]

These results provide scientific evidence for the use of E. longifolia as a potential analgesic and anti-inflammatory agent.Feb 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Pharm Res. 2016 Mar ;39(3):421-8. Epub 2016 Jan 30. PMID: 26832325
Article Published Date : Feb 29, 2016
Study Type : Animal Study
Additional Links
Substances : Tongkat Ali
Diseases : Inflammation
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor
Additional Keywords : Dose Response, Superiority of Natural Substances versus Drugs
Problem Substances : Diclofenac
[+]

Tongkat Ali (Euycoma longifolia) improved sexual performance and testosterone but not motivation in sluggish rats. Nov 12, 2009

Pubmed Data : J Ethnopharmacol. 2009 Nov 12;126(2):308-13. Epub 2009 Aug 22. PMID: 19703544
Article Published Date : Nov 12, 2009
Study Type : Animal Study
Additional Links
Substances : Tongkat Ali
Diseases : Erectile Dysfunction, Low Testosterone, Sexual Dysfunction
Pharmacological Actions : Secretagogue
[+]

Tongkat Ali demonstrated anti-protozoal activity against Blastocystis sp. isolates and showed a sizeable reduction in the cell count which was comparable with Metronidazole.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Parasit Vectors. 2015 ;8:332. Epub 2015 Jun 18. PMID: 26082155
Article Published Date : Dec 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Parasitic Intestinal Diseases
Pharmacological Actions : Antiprotozoal Agents
Additional Keywords : Natural Substances Versus Drugs
[+]

Tongkat Ali improves sexual arousal in sexually sluggish old male rats. Jan 01, 2004

Pubmed Data : J Basic Clin Physiol Pharmacol. 2004;15(3-4):303-9. PMID: 15803965
Article Published Date : Jan 01, 2004
Study Type : Animal Study
Additional Links
Substances : Tongkat Ali
Diseases : Erectile Dysfunction, Low Libido
Pharmacological Actions : Aphrodisiac
[+]

A review of medicinal plants that exhibit anti-Toxoplasma effects.Jul 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Trop Med. 2016 Aug ;9(8):730-4. Epub 2016 Jun 28. PMID: 27569880
Article Published Date : Jul 31, 2016
Study Type : Review
Additional Links
Substances : Capparis spinosa (caper), Ginger, Juniper, Myrrh, Sophora Flavescens, Tongkat Ali, Turmeric
Diseases : Toxoplasma gondii Infection
Pharmacological Actions : Antiparasitic Agents
[+]

A systematic review on antimicrobial and antiparasitic activity of Eurycoma longifolia Jack.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2022 ;2022:4999797. Epub 2022 Jul 6. PMID: 35845951
Article Published Date : Dec 31, 2021
Study Type : Review
Additional Links
Substances : Tongkat Ali
Diseases : Bacillus Cereus infection, Bacillus subtilis infections, Candida Albicans, Escherichia coli Infections, Plasmodium Infections, Pseudomonas aeruginosa, Schistosomiasis, Shigellosis, Staphylococcus aureus infection, Steptococcus Mutans Infections
Pharmacological Actions : Anti-Bacterial Agents, Antimicrobial, Antiparasitic Agents
Additional Keywords : Plant Extracts
[+]

E. longifolia can induce apoptosis cell death on MDA-MB-231 and MCF-7 cells.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:8811236. Epub 2021 Jan 30. PMID: 33603822
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Apoptotic
[+]

Eurycoma longifolia root extract was found to have toxoplasmacidal properties in vitro. Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2012 ;12:91. Epub 2012 Jul 10. PMID: 22781137
Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Toxoplasma gondii Infection
Pharmacological Actions : Antiparasitic Agents
Additional Keywords : Plant Extracts
[+]

Eurycoma longifolia: an overview on the pharmacological properties for the treatment of common cancer.Mar 29, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Public Health Afr. 2023 Mar 30 ;14(Suppl 1):2495. Epub 2023 Mar 16. PMID: 37492537
Article Published Date : Mar 29, 2023
Study Type : Review
Additional Links
Substances : Tongkat Ali
Diseases : Liver Cancer, Lung Cancer, Nasopharyngeal Cancer, Prostate Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Eurycomanol and eurycomanone as potent inducers for cell-cycle arrest and apoptosis in small and large human lung cancer cell lines.Sep 01, 2022

Pubmed Data : Nat Prod Res. 2022 Sep 2:1-7. Epub 2022 Sep 2. PMID: 36054770
Article Published Date : Sep 01, 2022
Study Type : In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Quassinoids from Eurycoma longifolia with antiviral activities by inhibiting dengue virus replication.Jan 31, 2023

Pubmed Data : Phytomedicine. 2023 Feb ;110:154650. Epub 2023 Jan 5. PMID: 36649670
Article Published Date : Jan 31, 2023
Study Type : In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Dengue
Pharmacological Actions : Antiviral Agents
[+]

Quassinoidsare anti-coronavirus compounds.Dec 22, 2022

Pubmed Data : J Nat Prod. 2022 Dec 23 ;85(12):2779-2788. Epub 2022 Nov 18. PMID: 36399766
Article Published Date : Dec 22, 2022
Study Type : In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Common Cold, Coronavirus Infection
Pharmacological Actions : Antiviral Agents
[+]

Tongkat Ali (Euycoma longifolia) exhibits anti-tumor, anti-schistomosomal and ant-malarial activity, in vito. Sep 01, 2002

Pubmed Data : J Ethnopharmacol. 2002 Sep;82(1):55-8. PMID: 12169407
Article Published Date : Sep 01, 2002
Study Type : In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Malaria, Schistosomiasis, Tumors
Pharmacological Actions : Anti-Tumor, Antimalarials
[+]

Tongkat Ali exerts anti-proliferative action and growth inhibition on breast cancer cells. Sep 01, 2007

Pubmed Data : Anticancer Res. 2007 Sep-Oct;27(5A):3425-30. PMID: 17970090
Article Published Date : Sep 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Tongkat Ali has antiproliferative and apoptotic activity against breast cancer cells. May 01, 2005

Pubmed Data : Anticancer Res. 2005 May-Jun;25(3B):2205-13. PMID: 16158965
Article Published Date : May 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic

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