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21 Diseases Researched for Tongkat Ali
NameACCKFocus
Erectile Dysfunction324Locked
Androgen Deficiency110Locked
Toxoplasma gondii Infection34Locked
Breast Cancer33Locked
Acetaminophen (Tylenol) Toxicity 12Locked
Diabetes Mellitus: Type 212Locked
Diabetes Mellitus: Type 2: Prevention12Locked
Infertility12Locked
Infertility: Male12Locked
Inflammation12Locked
Insulin Resistance12Locked
Kidney Damage: Drug-Induced12Locked
Low Libido12Locked
Low Testosterone12Locked
Parasitic Intestinal Diseases12Locked
Sexual Dysfunction12Locked
Toxoplasmosis12Locked
Breast Cancer: Triple Negative 11Locked
Malaria11Locked
Schistosomiasis11Locked
Tumors11Locked
15 Pharmacological Actions Researched for Tongkat Ali
NameACCKFocus
Immunomodulatory110Locked
Antiparasitic Agents34Locked
Apoptotic33Locked
Analgesics12Locked
Anti-Inflammatory Agents12Locked
Antiproliferative 22Locked
Antiprotozoal Agents12Locked
Aphrodisiac 12Locked
Cyclooxygenase 2 Inhibitors12Locked
Fertility Agents: Male12Locked
NF-kappaB Inhibitor12Locked
Renoprotective12Locked
Secretagogue12Locked
Anti-Tumor11Locked
Antimalarials11Locked

View the Evidence:
26 Abstracts with Tongkat Ali Research

[+]

This systematic review and meta-analysis of the literature supports the possible use of E. longifolia supplementation for enhancing testosterone production.Aug 03, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicina (Kaunas). 2022 Aug 4 ;58(8). Epub 2022 Aug 4. PMID: 36013514
Article Published Date : Aug 03, 2022
Study Type : Meta Analysis, Review
Additional Links
Substances : Tongkat Ali
Diseases : Testosterone: Too Low
Additional Keywords : Plant Extracts
[+]

Based on current evidence, the herbal extract of Tongkat Ali may have clinical effect on erectile function.Sep 30, 2015

Pubmed Data : Complement Ther Med. 2015 Oct ;23(5):693-8. Epub 2015 Jul 31. PMID: 26365449
Article Published Date : Sep 30, 2015
Study Type : Meta Analysis, Review
Additional Links
Substances : Tongkat Ali
Diseases : Erectile Dysfunction
Additional Keywords : Plant Extracts
[+]

Exercise associated or not to the intake of Eurycoma longifolia improves strength and cardiorespiratory fitness in men with androgen deficiency.Jan 31, 2021

Pubmed Data : Complement Ther Clin Pract. 2021 Feb ;42:101301. Epub 2021 Jan 5. PMID: 33445146
Article Published Date : Jan 31, 2021
Study Type : Human Study
Additional Links
Substances : Tongkat Ali
Diseases : Androgen Deficiency
Therapeutic Actions : Exercise
[+]

Ingestion of the root water extract of Tongkat Ali enhances comprehensive immunity in both middle-aged men and women.Jan 26, 2016

Pubmed Data : Phytother Res. 2016 Jan 27. Epub 2016 Jan 27. PMID: 26816234
Article Published Date : Jan 26, 2016
Study Type : Human Study
Additional Links
Substances : Tongkat Ali
Pharmacological Actions : Immunomodulatory
Additional Keywords : Plant Extracts
[+]

Supplementation of Physta® at 200 mg was able to increase the serum total testosterone, reduce fatigue and improve the quality of life in ageing men.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Nutr Res. 2021 ;65. Epub 2021 May 19. PMID: 34262417
Article Published Date : Dec 31, 2020
Study Type : Human Study
Additional Links
Substances : Tongkat Ali
Diseases : Aging, Testosterone: Too Low
[+]

The combination of Eurycoma longifolia and concurrent training improved erectile function and increased total testosterone levels in men with ADAM.Feb 28, 2021

Pubmed Data : Maturitas. 2021 Mar ;145:78-85. Epub 2020 Dec 10. PMID: 33541567
Article Published Date : Feb 28, 2021
Study Type : Human Study
Additional Links
Substances : Tongkat Ali
Diseases : Aging, Androgen Deficiency, Erectile Dysfunction
Additional Keywords : Phytotherapy, Plant Extracts
[+]

The effect of Eurycoma Longifolia on the regulation of reproductive hormones in young males.Apr 30, 2021

Pubmed Data : Andrologia. 2021 May ;53(4):e14001. Epub 2021 Feb 9. PMID: 33559971
Article Published Date : Apr 30, 2021
Study Type : Human Study
Additional Links
Substances : Tongkat Ali
Diseases : Testosterone: Too Low
Additional Keywords : Plant Extracts
[+]

DHOK exerts anti-cancer effect through autophagy inhibition in colorectal cancer. Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Dev Biol. 2021 ;9:760022. Epub 2021 Dec 17. PMID: 34977014
Article Published Date : Dec 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Colorectal Cancer
Pharmacological Actions : Apoptotic, Autophagy Inhibitors
[+]

Active fractions from E. longifolia have potent and selective antiproliferative activity against T. gondii tachyzoites.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2012 ;17(8):9207-19. Epub 2012 Aug 2. PMID: 22858841
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Tongkat Ali
Diseases : Toxoplasma gondii Infection, Toxoplasmosis
Pharmacological Actions : Antiparasitic Agents
Additional Keywords : Plant Extracts
[+]

Nephroprotective effect of herbal extract Eurycoma longifolia on paracetamol-induced nephrotoxicity.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:4916519. Epub 2019 May 13. PMID: 31214269
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Tongkat Ali
Diseases : Acetaminophen (Tylenol) Toxicity , Kidney Damage: Drug-Induced
Pharmacological Actions : Renoprotective
Problem Substances : Acetaminophen, Paracetamol
[+]

Serum alpha-2-HS glycoprotein was reduced in rats treated with standardized E. longifolia extract.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2015 ;6:211. Epub 2015 Sep 23. PMID: 26441666
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Tongkat Ali
Diseases : Diabetes Mellitus: Type 2, Diabetes Mellitus: Type 2: Prevention, Infertility, Insulin Resistance
Additional Keywords : Risk Reduction
[+]

These results proved the efficacy of quassinoids on increasing sperm count in rats.Apr 21, 2016

Pubmed Data : J Ethnopharmacol. 2016 Apr 22 ;182:80-9. Epub 2016 Feb 16. PMID: 26899442
Article Published Date : Apr 21, 2016
Study Type : Animal Study
Additional Links
Substances : Tongkat Ali
Diseases : Infertility: Male
Pharmacological Actions : Fertility Agents: Male
Additional Keywords : Plant Extracts
[+]

These results provide scientific evidence for the use of E. longifolia as a potential analgesic and anti-inflammatory agent.Feb 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Pharm Res. 2016 Mar ;39(3):421-8. Epub 2016 Jan 30. PMID: 26832325
Article Published Date : Feb 29, 2016
Study Type : Animal Study
Additional Links
Substances : Tongkat Ali
Diseases : Inflammation
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor
Additional Keywords : Dose Response, Superiority of Natural Substances versus Drugs
Problem Substances : Diclofenac
[+]

Tongkat Ali (Euycoma longifolia) improved sexual performance and testosterone but not motivation in sluggish rats. Nov 12, 2009

Pubmed Data : J Ethnopharmacol. 2009 Nov 12;126(2):308-13. Epub 2009 Aug 22. PMID: 19703544
Article Published Date : Nov 12, 2009
Study Type : Animal Study
Additional Links
Substances : Tongkat Ali
Diseases : Erectile Dysfunction, Low Testosterone, Sexual Dysfunction
Pharmacological Actions : Secretagogue
[+]

Tongkat Ali demonstrated anti-protozoal activity against Blastocystis sp. isolates and showed a sizeable reduction in the cell count which was comparable with Metronidazole.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Parasit Vectors. 2015 ;8:332. Epub 2015 Jun 18. PMID: 26082155
Article Published Date : Dec 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Parasitic Intestinal Diseases
Pharmacological Actions : Antiprotozoal Agents
Additional Keywords : Natural Substances Versus Drugs
[+]

Tongkat Ali improves sexual arousal in sexually sluggish old male rats. Jan 01, 2004

Pubmed Data : J Basic Clin Physiol Pharmacol. 2004;15(3-4):303-9. PMID: 15803965
Article Published Date : Jan 01, 2004
Study Type : Animal Study
Additional Links
Substances : Tongkat Ali
Diseases : Erectile Dysfunction, Low Libido
Pharmacological Actions : Aphrodisiac
[+]

A review of medicinal plants that exhibit anti-Toxoplasma effects.Jul 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Trop Med. 2016 Aug ;9(8):730-4. Epub 2016 Jun 28. PMID: 27569880
Article Published Date : Jul 31, 2016
Study Type : Review
Additional Links
Substances : Capparis spinosa (caper), Ginger, Juniper, Myrrh, Sophora Flavescens, Tongkat Ali, Turmeric
Diseases : Toxoplasma gondii Infection
Pharmacological Actions : Antiparasitic Agents
[+]

A systematic review on antimicrobial and antiparasitic activity of Eurycoma longifolia Jack.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2022 ;2022:4999797. Epub 2022 Jul 6. PMID: 35845951
Article Published Date : Dec 31, 2021
Study Type : Review
Additional Links
Substances : Tongkat Ali
Diseases : Bacillus Cereus infection, Bacillus subtilis infections, Candida Albicans, Escherichia coli Infections, Plasmodium Infections, Pseudomonas aeruginosa, Schistosomiasis, Shigellosis, Staphylococcus aureus infection, Steptococcus Mutans Infections
Pharmacological Actions : Anti-Bacterial Agents, Antimicrobial, Antiparasitic Agents
Additional Keywords : Plant Extracts
[+]

E. longifolia can induce apoptosis cell death on MDA-MB-231 and MCF-7 cells.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:8811236. Epub 2021 Jan 30. PMID: 33603822
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Apoptotic
[+]

Eurycoma longifolia root extract was found to have toxoplasmacidal properties in vitro. Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2012 ;12:91. Epub 2012 Jul 10. PMID: 22781137
Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Toxoplasma gondii Infection
Pharmacological Actions : Antiparasitic Agents
Additional Keywords : Plant Extracts
[+]

Eurycomanol and eurycomanone as potent inducers for cell-cycle arrest and apoptosis in small and large human lung cancer cell lines.Sep 01, 2022

Pubmed Data : Nat Prod Res. 2022 Sep 2:1-7. Epub 2022 Sep 2. PMID: 36054770
Article Published Date : Sep 01, 2022
Study Type : In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Quassinoids from Eurycoma longifolia with antiviral activities by inhibiting dengue virus replication.Jan 31, 2023

Pubmed Data : Phytomedicine. 2023 Feb ;110:154650. Epub 2023 Jan 5. PMID: 36649670
Article Published Date : Jan 31, 2023
Study Type : In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Dengue
Pharmacological Actions : Antiviral Agents
[+]

Quassinoidsare anti-coronavirus compounds.Dec 22, 2022

Pubmed Data : J Nat Prod. 2022 Dec 23 ;85(12):2779-2788. Epub 2022 Nov 18. PMID: 36399766
Article Published Date : Dec 22, 2022
Study Type : In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Common Cold, Coronavirus Infection
Pharmacological Actions : Antiviral Agents
[+]

Tongkat Ali (Euycoma longifolia) exhibits anti-tumor, anti-schistomosomal and ant-malarial activity, in vito. Sep 01, 2002

Pubmed Data : J Ethnopharmacol. 2002 Sep;82(1):55-8. PMID: 12169407
Article Published Date : Sep 01, 2002
Study Type : In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Malaria, Schistosomiasis, Tumors
Pharmacological Actions : Anti-Tumor, Antimalarials
[+]

Tongkat Ali exerts anti-proliferative action and growth inhibition on breast cancer cells. Sep 01, 2007

Pubmed Data : Anticancer Res. 2007 Sep-Oct;27(5A):3425-30. PMID: 17970090
Article Published Date : Sep 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Tongkat Ali has antiproliferative and apoptotic activity against breast cancer cells. May 01, 2005

Pubmed Data : Anticancer Res. 2005 May-Jun;25(3B):2205-13. PMID: 16158965
Article Published Date : May 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic

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