Toona sinensis

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31 Diseases Researched for Toona sinensis
NameACCKFocus
Leukemia27Locked
Brain Inflammation 35Locked
Lipopolysaccharide-Induced Toxicity45Locked
Inflammation34Locked
Parkinson's Disease24Locked
Lung Cancer23Locked
Oral Cancer23Locked
Acetaminophen (Tylenol) Toxicity 12Locked
Chemically-Induced Liver Damage12Locked
Diabetes Mellitus: Type 112Locked
Diabetes Mellitus: Type 212Locked
Diabetic Complications12Locked
Diabetic Nephropathy12Locked
Liver Cancer22Locked
Oral Cancer: Prevention12Locked
Osteosarcoma12Locked
Pain12Locked
Sepsis12Locked
Atherosclerosis11Locked
Brain: Microglial Activation11Locked
Colorectal Cancer11Locked
Coronaviridae Infections11Locked
H1N1 Infection11Locked
Influenza A11Locked
Insulin Resistance11Locked
Kidney Cancer11Locked
Leukemia: Acute promyelocytic leukemia 11Locked
Neurodegenerative Diseases11Locked
Nonalcoholic fatty liver disease (NAFLD)11Locked
SARS11Locked
Staphylococcus aureus infection11Locked
31 Pharmacological Actions Researched for Toona sinensis
NameACCKFocus
Apoptotic1119Locked
Antiproliferative 613Locked
Anti-Inflammatory Agents812Locked
Chemopreventive38Locked
Antioxidants57Locked
Cell cycle arrest35Locked
Hepatoprotective35Locked
NF-kappaB Inhibitor35Locked
Cyclooxygenase 2 Inhibitors34Locked
Neuroprotective Agents24Locked
Anti-Apoptotic23Locked
Bcl-2 protein down-regulation23Locked
Analgesics12Locked
Anti-metastatic22Locked
Anticarcinogenic Agents12Locked
Antineoplastic Agents22Locked
Antinoceceptive 12Locked
Antiviral Agents22Locked
Interleukin-1 beta downregulation12Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor22Locked
NF-E2-Related Factor-2 (Nrf2) Modulator12Locked
Renoprotective12Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor22Locked
Anti-Bacterial Agents11Locked
Cytotoxic11Locked
Hypolipidemic11Locked
Immunomodulatory11Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor11Locked
PPAR-Gamma Up-Regulation11Locked
Prophylactic Agents11Locked
Vascular Endothelial Growth Factor Inhibitors11Locked

View the Evidence:
25 Abstracts with Toona sinensis Research

[+]

Extracts of T. sinensis inhibited cell proliferation and induced apoptosis in human leukemia HL-60 cells.Aug 31, 2014

Pubmed Data : Bioorg Med Chem Lett. 2014 Sep 1 ;24(17):4286-90. Epub 2014 Jul 14. PMID: 25074815
Article Published Date : Aug 31, 2014
Study Type : Human In Vitro
Additional Links
Substances : Toona sinensis
Diseases : Leukemia
Pharmacological Actions : Antiproliferative , Apoptotic, Chemopreventive
Additional Keywords : Plant Extracts
[+]

Polyphenols from Toona sinensis seeds alleviate neuroinflammation in rats with Parkinson's disease.Aug 31, 2019

Pubmed Data : Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2019 Sep ;35(9):794-799. PMID: 31750820
Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Polyphenols, Toona sinensis
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Polyphenols from Toona sinensiss seeds alleviate neuroinflammation induced by 6-hydroxydopamine.Jun 16, 2020

Pubmed Data : Neurochem Res. 2020 Jun 17. Epub 2020 Jun 17. PMID: 32556929
Article Published Date : Jun 16, 2020
Study Type : Animal Study
Additional Links
Substances : Polyphenols, Toona sinensis
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Quercetin from Toona sinensis leaves can be viewed as a promising dietary agent that can be used to reduce the risk of diabetes mellitus.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Diabetes Res. 2016 ;2016:8492780. Epub 2016 Nov 15. PMID: 27975068
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Quercetin, Toona sinensis
Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2, Diabetic Complications
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, NF-kappaB Inhibitor
Additional Keywords : Risk Reduction
[+]

Quercitrin attenuates acetaminophen induced liver damage by the activation of defensive genes and the inhibition of pro-inflammatory genes.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2016 ;8(7). Epub 2016 Jul 15. PMID: 27428996
Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Toona sinensis
Diseases : Acetaminophen (Tylenol) Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, NF-E2-Related Factor-2 (Nrf2) Modulator
Problem Substances : Acetaminophen, Paracetamol
[+]

Structural characterization and hepatoprotective activities of polysaccharides from the leaves of Toona sinensis.May 14, 2019

Pubmed Data : Carbohydr Polym. 2019 May 15 ;212:89-101. Epub 2019 Feb 12. PMID: 30832884
Article Published Date : May 14, 2019
Study Type : Animal Study
Additional Links
Substances : Toona sinensis
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Hepatoprotective
Additional Keywords : Polysaccharides
[+]

T. sinensis seed extract has protective effects on diabetic nephropathy in rats.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Genet Mol Res. 2016 ;15(1). Epub 2016 Mar 24. PMID: 27050993
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Toona sinensis
Diseases : Diabetic Nephropathy
Pharmacological Actions : Antioxidants, Renoprotective
[+]

This report confirms the antitumor activity of this nutritious vegetable potentially against leukemia.May 03, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Cancer Ther. 2016 May 4. Epub 2016 May 4. PMID: 27151590
Article Published Date : May 03, 2016
Study Type : Animal Study
Additional Links
Substances : Toona sinensis
Diseases : Leukemia
Pharmacological Actions : Apoptotic
Additional Keywords : Plant Extracts
[+]

Toona sinensis has anti-visceral pain properties comparable with those of rofecoxib and diclofenac.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2015 ;15:70. Epub 2015 Mar 19. PMID: 25886358
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Toona sinensis
Diseases : Pain
Pharmacological Actions : Analgesics, Antinoceceptive
Additional Keywords : Natural Substances Versus Drugs, Plant Extracts
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Toona sinensis leaf aqueous extract displays activity against sepsis in both in vitro and in vivo models.May 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Kaohsiung J Med Sci. 2014 Jun ;30(6):279-85. Epub 2014 Apr 3. PMID: 24835347
Article Published Date : May 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Toona sinensis
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Sepsis
Additional Keywords : Plant Extracts
[+]

Toona sinensis leaf extract might be a promising candidate for the prevention of oral cancer.Jun 14, 2016

Pubmed Data : Arch Oral Biol. 2016 Jun 15 ;70:130-142. Epub 2016 Jun 15. PMID: 27348052
Article Published Date : Jun 14, 2016
Study Type : Animal Study
Additional Links
Substances : Toona sinensis
Diseases : Oral Cancer, Oral Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Apoptotic, Chemopreventive
Additional Keywords : Plant Extracts
[+]

Toona sinensis leaf has potential to be a promising anti-osteosarcoma treatment.Aug 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Cancer Ther. 2017 Sep ;16(3):397-405. Epub 2016 Nov 22. PMID: 27879376
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Toona sinensis
Diseases : Osteosarcoma
Pharmacological Actions : Apoptotic
[+]

Aqueous extracts from Toona sinensis roem may be used as an alternative treatment and prophylaxis against influenza A virus. Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2013 ;2013:479718. Epub 2013 Sep 2. PMID: 24073006
Article Published Date : Dec 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Toona sinensis
Diseases : H1N1 Infection, Influenza A
Pharmacological Actions : Antiviral Agents, Prophylactic Agents
Additional Keywords : Gene Expression, Plant Extracts, Superiority of Natural Substances versus Drugs
[+]

Aqueous extracts of Toona sinensis leaves inhibit renal carcinoma cell growth and migration.Apr 30, 2016

Pubmed Data : Nutr Cancer. 2016 May-Jun;68(4):654-66. Epub 2016 Apr 26. PMID: 27115866
Article Published Date : Apr 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Toona sinensis
Diseases : Kidney Cancer
Pharmacological Actions : Anti-metastatic, Apoptotic, Cell cycle arrest, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors
Additional Keywords : Plant Extracts
[+]

Essential oil from Toona sinensis possessed antibacterial activity against Staphylococcus aureus and significant cytotoxicity against cancer cells.May 27, 2014

Pubmed Data : J Ethnopharmacol. 2014 May 28 ;154(1):198-205. Epub 2014 Apr 12. PMID: 24726685
Article Published Date : May 27, 2014
Study Type : In Vitro Study
Additional Links
Substances : Toona sinensis
Diseases : Liver Cancer, Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents, Antineoplastic Agents, Apoptotic, Bcl-2 protein down-regulation
Additional Keywords : Essential Oils
[+]

Extracts of Toona sinensis and fermented culture broths of Antrodia camphorata synergistically cause apoptotic cell death in promyelocytic leukemia cells. Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Cancer Ther. 2020 Jan-Dec;19:1534735420923734. PMID: 32618215
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Antrodia camphorata, Toona sinensis
Diseases : Leukemia: Acute promyelocytic leukemia
Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic, Apoptotic, Cyclooxygenase 2 Inhibitors, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords : Natural Substance Synergy
[+]

Extracts of Toona sinensis leaves could be used in the treatment of neurodegenerative diseases by inhibition of inflammatory mediator production in activated microglia.Jan 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Kaohsiung J Med Sci. 2014 Feb ;30(2):73-81. Epub 2013 Nov 1. PMID: 24444536
Article Published Date : Jan 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Toona sinensis
Diseases : Brain: Microglial Activation, Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Polyphenol-rich extracts from Toona sinensis bark and fruit ameliorate free fatty acid-induced lipogenesis.Oct 10, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Med. 2019 Oct 11 ;8(10). Epub 2019 Oct 11. PMID: 31614650
Article Published Date : Oct 10, 2019
Study Type : In Vitro Study
Additional Links
Substances : Toona sinensis
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Hepatoprotective, Hypolipidemic
[+]

Quercetrin from Toona sinensis leaves induces cell cycle arrest and apoptosis in human colorectal cancer SW620 cells.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Rep. 2017 Dec ;38(6):3319-3326. Epub 2017 Oct 17. PMID: 29039609
Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Quercetin, Toona sinensis
Diseases : Colorectal Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Antiproliferative, Apoptotic, COLORECTAL CANCER, QUERCETIN, Toona sinensis
[+]

Recovery of immune activity by administration of polysaccharides of Toona sinensis.Jul 12, 2020

Pubmed Data : Nat Prod Res. 2020 Jul 13:1-5. Epub 2020 Jul 13. PMID: 32657144
Article Published Date : Jul 12, 2020
Study Type : In Vitro Study
Additional Links
Substances : Toona sinensis
Pharmacological Actions : Immunomodulatory
Additional Keywords : Polysaccharides
[+]

Stem bark of Toona sinensis contained tirucallane triterpenoids that displayed cytotoxic activity against A-549 cells.Jun 30, 2016

Pubmed Data : Fitoterapia. 2016 Jul ;112:97-103. Epub 2016 May 20. PMID: 27215130
Article Published Date : Jun 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Toona sinensis
Diseases : Lung Cancer
Pharmacological Actions : Cytotoxic
[+]

Toona Sinensis ameliorates insulin resistance via AMPK and PPARγ pathways.May 31, 2015

Pubmed Data : Food Funct. 2015 Jun ;6(6):1855-64. PMID: 25940430
Article Published Date : May 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Toona sinensis
Diseases : Insulin Resistance
Pharmacological Actions : PPAR-Gamma Up-Regulation
Additional Keywords : Plant Extracts
[+]

Toona sinensis extract inhibits SARS coronavirus replication. Oct 30, 2008

Pubmed Data : J Ethnopharmacol. 2008 Oct 30;120(1):108-11. Epub 2008 Aug 9. PMID: 18762235
Article Published Date : Oct 30, 2008
Study Type : In Vitro Study
Additional Links
Substances : Toona sinensis
Diseases : Coronaviridae Infections, SARS
Pharmacological Actions : Antiviral Agents
[+]

Toona sinensis may be useful for the prevention of atherosclerosis.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2014 ;2014:901315. Epub 2014 Mar 4. PMID: 24723997
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Toona sinensis
Diseases : Atherosclerosis, Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor
Additional Keywords : Plant Extracts
[+]

Toona sinensis modulates autophagy and cytokines in lipopolysaccharide-induced RAW 264.7 macrophages.Jun 17, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2020 Jun 18 ;129:110386. Epub 2020 Jun 18. PMID: 32563986
Article Published Date : Jun 17, 2020
Study Type : In Vitro Study
Additional Links
Substances : Toona sinensis
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants

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