Trigonelline

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9 Diseases Researched for Trigonelline

Name	AC	CK
Auditory neuropathy	1	2
Diabetes Mellitus: Type 1	1	2
Diabetic Neuropathies	1	2
Hyperglycemia	1	2
Insulin Resistance	1	2
Insulin: Low	1	2
Diabetes Mellitus: Type 2	1	1
Dopamine Deficiency	1	1
Neurodegenerative Diseases	1	1

4 Pharmacological Actions Researched for Trigonelline

Name	AC	CK
Hypoglycemic Agents	2	3
Insulin Sensitizers	1	2
Dopaminergic	1	1
Neuritogenic	1	1

Research Articles 5
Cumulative Knowledge Score 8
Overall Research Rating GOOD

View the Evidence:
5 Abstracts with Trigonelline Research

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Coffee

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Coffee consumption may have a protective/restorative function on diabetic auditory neuropathy. Aug 29, 2008

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Pubmed Data : Neurosci Lett. 2008 Aug 29;441(3):302-6. Epub 2008 Jun 22. PMID: 18586072

Article Published Date : Aug 29, 2008

Study Type : Animal Study

Additional Links

Substances : Coffee, Trigonelline

Diseases : Auditory neuropathy , Diabetic Neuropathies

[+]

Trigonelline has beneficial effect for diabetes through decreasing blood glucose and lipid levels, increasing insulin sensitivity index and insulin content, up-regulating antioxidant enzyme activity and decreasing lipid peroxidation.Dec 16, 2011

Click here to read the entire abstract

Pubmed Data : Fundam Clin Pharmacol. 2011 Dec 16. Epub 2011 Dec 16. PMID: 22172053

Article Published Date : Dec 16, 2011

Study Type : Animal Study

Additional Links

Substances : Trigonelline

Diseases : Diabetes Mellitus: Type 1, Hyperglycemia, Insulin: Low , Insulin Resistance

Pharmacological Actions : Hypoglycemic Agents, Insulin Sensitizers

[+]

Coffee contains a compound called trigonelline which promotes neurite outgrowth.Jul 01, 1999

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Pubmed Data : Biol Pharm Bull. 1999 Jul;22(7):679-82. PMID: 10443461

Article Published Date : Jul 01, 1999

Study Type : In Vitro Study

Additional Links

Substances : Coffee, Trigonelline

Diseases : Neurodegenerative Diseases

Pharmacological Actions : Neuritogenic

Additional Keywords : Trigonelline

[+]

Coffee contains compounds which stimulate dopamine release.Oct 13, 2011

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2011 Oct 13. Epub 2011 Oct 13. PMID: 22019894

Article Published Date : Oct 13, 2011

Study Type : In Vitro Study

Additional Links

Substances : 5-hydroxytryptamides, Caffeine, Catechols, Chlorogenic Acid, Coffee, N-methylpyridinium, Pyrogallol, Trigonelline

Diseases : Dopamine Deficiency

Pharmacological Actions : Dopaminergic

[+]

Preliminary investigation showed that pumpkin seeds possess hypoglycemic properties and could assist in maintaining glycemic control.Dec 31, 2013

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Pubmed Data : Crit Rev Food Sci Nutr. 2014 ;54(10):1322-9. PMID: 24564589

Article Published Date : Dec 31, 2013

Study Type : Review

Additional Links

Substances : Pumpkin Seeds, Trigonelline

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Hypoglycemic Agents

Research Articles 5
Cumulative Knowledge Score 8
Overall Research Rating GOOD

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Focus Your Research

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View the Evidence: 5 Abstracts with Trigonelline Research

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Currently Available Sorting Options

Coffee consumption may have a protective/restorative function on diabetic auditory neuropathy. Aug 29, 2008

Click here to read the entire abstract

Trigonelline has beneficial effect for diabetes through decreasing blood glucose and lipid levels, increasing insulin sensitivity index and insulin content, up-regulating antioxidant enzyme activity and decreasing lipid peroxidation.Dec 16, 2011

Click here to read the entire abstract

Coffee contains a compound called trigonelline which promotes neurite outgrowth.Jul 01, 1999

Click here to read the entire abstract

Coffee contains compounds which stimulate dopamine release.Oct 13, 2011

Click here to read the entire abstract

Preliminary investigation showed that pumpkin seeds possess hypoglycemic properties and could assist in maintaining glycemic control.Dec 31, 2013

Click here to read the entire abstract

Trigonelline Related Articles

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Trigonelline

View the Evidence:
5 Abstracts with Trigonelline Research