Triphala

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26 Diseases Researched for Triphala
NameACCKFocus
Gingivitis431Locked
Dental Plaque330Locked
Periodontal Diseases211Locked
Dental Diseases110Locked
Inflammation110Locked
Fibrosis15Locked
Rheumatoid Arthritis24Locked
Oxidative Stress23Locked
Alcohol Withdrawal12Locked
Anxiety Disorders12Locked
Arthritis12Locked
Bromobenzene Toxicity 12Locked
Cognitive Decline/Dysfunction12Locked
Gout12Locked
Pancreatic Cancer12Locked
Pseudomonas aeruginosa12Locked
Staphylococcus aureus infection12Locked
Streptococcus pyogenes 12Locked
Wound Healing12Locked
Alzheimer's Disease11Locked
Cancers: All11Locked
Colon Cancer11Locked
Dental Caries11Locked
Dental Caries: Children11Locked
Salmonella Infections11Locked
Typhoid Fever11Locked
19 Pharmacological Actions Researched for Triphala
NameACCKFocus
Antimicrobial541Locked
Anti-Inflammatory Agents416Locked
Anti-Bacterial Agents313Locked
Gastrointestinal Agents110Locked
Anti-Fibrotic15Locked
Antioxidants23Locked
Neuroprotective Agents23Locked
Radioprotective23Locked
Anticholesteremic Agents12Locked
Immunomodulatory22Locked
NF-kappaB Inhibitor12Locked
Prostaglandin PGE2 downregulation12Locked
Renoprotective12Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor12Locked
Vascular Endothelial Growth Factor Inhibitors12Locked
Antiproliferative 11Locked
Apoptotic11Locked
Chemopreventive11Locked
Chemotherapeutic11Locked

View the Evidence:
32 Abstracts with Triphala Research

[+]

Modulatory effects of triphala and manjistha dietary supplementation on human gut microbiota.Sep 17, 2020

Pubmed Data : J Altern Complement Med. 2020 Sep 18. Epub 2020 Sep 18. PMID: 32955913
Article Published Date : Sep 17, 2020
Study Type : Human Study
Additional Links
Substances : Triphala
Pharmacological Actions : Gastrointestinal Agents
[+]

The antiplaque and antigingivitis activity of triphala closely parallels that of chlorhexidine.Dec 31, 2013

Pubmed Data : Oral Health Prev Dent. 2014 ;12(3):209-17. PMID: 25197734
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Substances : Triphala
Diseases : Dental Plaque, Gingivitis
Pharmacological Actions : Antimicrobial
Additional Keywords : Chemical: Chlorhexidine, Natural Substances Versus Drugs, Plant Extracts
[+]

The effectiveness of triphala in the reduction of plaque and gingivitis was comparable to chlorhexidine without side effects.May 21, 2014

Pubmed Data : J Investig Clin Dent. 2014 May 22. Epub 2014 May 22. PMID: 24850703
Article Published Date : May 21, 2014
Study Type : Human Study
Additional Links
Substances : Triphala
Diseases : Dental Plaque, Gingivitis
Pharmacological Actions : Antimicrobial
Additional Keywords : Natural Substances Versus Drugs
[+]

The results showed that 0.4% triphala and 0.12% CHX have similar inhibitory effect on plaque accumulation, gingivitis, and growth of S. mutans, S. sanguinis.Oct 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Indian Soc Periodontol. 2021 Nov-Dec;25(6):518-524. Epub 2021 Nov 1. PMID: 34898918
Article Published Date : Oct 31, 2021
Study Type : Human Study
Additional Links
Substances : Triphala
Diseases : Dental Plaque, Gingivitis, Steptococcus Mutans Infections
Pharmacological Actions : Anti-Inflammatory Agents, Antimicrobial
Additional Keywords : Mouthwash, Natural Substances Versus Drugs
[+]

Triphala has antimicrobial effects against numerous oral microorganisms.Aug 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Dent Res. 2012 Sep-Oct;23(5):696. PMID: 23422630
Article Published Date : Aug 31, 2012
Study Type : Human Study
Additional Links
Substances : Triphala
Diseases : Dental Diseases
Pharmacological Actions : Anti-Bacterial Agents, Antimicrobial
Additional Keywords : Plant Extracts
[+]

Triphala mouthwash (herbal) is an effective antiplaque agent like 0.2% chlorhexidine.May 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Periodontal Implant Sci. 2014 Jun ;44(3):134-40. Epub 2014 Jun 5. PMID: 24921057
Article Published Date : May 31, 2014
Study Type : Human Study
Additional Links
Substances : Triphala
Diseases : Dental Plaque, Gingivitis, Inflammation, Periodontal Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antimicrobial
Additional Keywords : Chemical: Chlorhexidine, Natural Substances Versus Drugs, Plant Extracts
[+]

Chebulagic acid and Chebulinic acid inhibit TGF-β1 induced fibrotic changes in the chorio-retinal endothelial cells by inhibiting ERK phosphorylation.Jan 01, 2019

Pubmed Data : Microvasc Res. 2019 01 ;121:14-23. Epub 2018 Sep 4. PMID: 30189210
Article Published Date : Jan 01, 2019
Study Type : Human In Vitro
Additional Links
Substances : Tannic Acid, Triphala
Diseases : Fibrosis
Pharmacological Actions : Anti-Fibrotic
Additional Keywords : Plant Extracts
[+]

A polyherbal formula is comparable to the benzodiazepiene drug alprazolam in reducing ethanol withdrawal-induced anxiety behavior. Jan 01, 2011

Pubmed Data : Evid Based Complement Alternat Med. 2011;2011. Epub 2010 Sep 7. PMID: 20953426
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Ashwagandha, Green Tea, Holy Basil, Shilajit, Triphala
Diseases : Alcohol Withdrawal, Anxiety Disorders
Additional Keywords : Benzodiazepine Alternatives, Drug: Alprazolam, Natural Substances Versus Drugs
[+]

An Ayurvedic herbal formula, Triphala, reduces symptoms of arthritis in a mouse experimental model. Sep 01, 2007

Pubmed Data : 1: Phytother Res. 2007 Sep;21(9):889-94.PMID:17533629
Article Published Date : Sep 01, 2007
Study Type : Animal Study
Additional Links
Substances : Triphala
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Hepatoprotective effects of different extracts from triphala against CCl4-induced acute liver injury.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2021 ;12:664607. Epub 2021 Jul 5. PMID: 34290606
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Triphala
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Hepatoprotective, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

High-salt- and cholesterol diet-associated cognitive impairment attenuated by tannins-enriched fraction of Emblica officinalis via inhibiting NF-kB pathway.Feb 01, 2018

Pubmed Data : Inflammopharmacology. 2018 Feb ;26(1):147-156. Epub 2018 Jan 15. PMID: 29335826
Article Published Date : Feb 01, 2018
Study Type : Animal Study
Additional Links
Substances : Amla Fruit, Phyllanthus emblica, Tannic Acid, Triphala
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Anticholesteremic Agents, Neuroprotective Agents, NF-kappaB Inhibitor
Additional Keywords : Plant Extracts
[+]

The results of this study suggest that triphala administration ameliorate bone and cartilage degradation during rheumatoid arthritis.Dec 31, 2014

Pubmed Data : Immunol Invest. 2015 ;44(4):411-26. PMID: 25942351
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Triphala
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

The traditional Ayurvedic formula known as triphala inhibits pancreatic cancer cell growth in vitro and in vivo. Oct 10, 2008

Pubmed Data : BMC Cancer. 2008 Oct 10;8:294. PMID: 18847491
Article Published Date : Oct 10, 2008
Study Type : Animal Study
Additional Links
Substances : Triphala
Diseases : Pancreatic Cancer
[+]

Triphala ameliorates nephropathy via inhibition of TGF-β1 and oxidative stress.Dec 31, 2019

Pubmed Data : Pharmacology. 2020 ;105(11-12):681-691. Epub 2020 Jul 16. PMID: 32674108
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Triphala
Diseases : Diabetic Nephropathy, Oxidative Stress
Pharmacological Actions : Antioxidants, Renoprotective, Transforming growth factor beta (TGF-β) inhibitor
Additional Keywords : Plant Extracts
[+]

Triphala churna a traditional formulation in ayurveda mitigates diabetic neuropathy.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2021 ;12:662000. Epub 2021 Jun 3. PMID: 34149415
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Triphala
Diseases : Diabetic Neuropathy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Renoprotective, Transforming growth factor beta (TGF-β) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Triphala churna ameliorates retinopathy in diabetes. Mar 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2022 Apr ;148:112711. Epub 2022 Feb 12. PMID: 35168075
Article Published Date : Mar 31, 2022
Study Type : Animal Study
Additional Links
Substances : Triphala
Diseases : Diabetic Retinopathy
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Triphala compares favorably to the drug Indomethacin as an anti-inflammatory against gouty arthritis while also improving antioxidant status. Jan 01, 2008

Pubmed Data : Vascul Pharmacol. 2008 Jan;48(1):14-20. Epub 2007 Nov 13. PMID: 18065272
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Triphala
Diseases : Gout
Additional Keywords : Natural Substances Versus Drugs
[+]

Triphala has a promising anti-inflammatory effect in the inflamed paw of arthritis-induced rats.Dec 31, 2014

Pubmed Data : Pharm Biol. 2015 Jan ;53(1):51-60. Epub 2014 Oct 7. PMID: 25289531
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Triphala
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor Inhibitors
[+]

Triphala promotes healing of infected full-thickness dermal wound.Jan 01, 2008

Pubmed Data : J Surg Res. 2008 Jan;144(1):94-101. Epub 2007 Jul 27. PMID: 17662304
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Triphala
Diseases : Pseudomonas aeruginosa, Staphylococcus aureus infection, Streptococcus pyogenes, Wound Healing
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Plant Extracts
[+]

Triphala treatment alleviated the nephrotoxic effects of bromobenzene by increasing the activities of antioxidant enzymes and reducing the levels of lipid peroxidation.Feb 28, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Integr Med. 2015 Mar ;13(2):115-21. PMID: 25797642
Article Published Date : Feb 28, 2015
Study Type : Animal Study
Additional Links
Substances : Triphala
Diseases : Bromobenzene Toxicity
Pharmacological Actions : Antioxidants, Renoprotective
[+]

A methanol extract of triphala suppressed proliferation independent of p53 status in HCT116 and in human colon cancer stem cells.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2015 ;2015:649263. Epub 2015 Jun 17. PMID: 26167492
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Triphala
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Cancer Stem Cells, Plant Extracts
[+]

Assessment of the cytotoxic activity of triphala: a semisolid traditional formulation on HepG2 cancer cell line. Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2021 ;2021:6689568. Epub 2021 Aug 11. PMID: 34471640
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Triphala
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Natural Substances Versus Drugs, Phytotherapy, Plant Extracts
[+]

Bael (Aegle marmelos), Bombax ceiba (Salmalia malabarica), Pomegranate (Punica granatum), Nutmeg (Myristica fragrans), Holarrhena antidysenterica, Arjuna (Terminalia arjuna) and Triphala exhibit strong anti-Salmonella typhi activity, in vitro. Aug 01, 2004

Pubmed Data : Phytother Res. 2004 Aug;18(8):670-3. PMID: 15476301
Article Published Date : Aug 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Arjuna, Bael , Bombax ceiba, Holarrhena antidysenterica, Nutmeg, Pomegranate, Triphala
Diseases : Salmonella Infections, Typhoid Fever
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Plant Extracts
[+]

Chebulinic acid derived from triphala is a promising antitumour agent in human colorectal carcinoma cell lines.Dec 26, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2018 Dec 27 ;18(1):342. Epub 2018 Dec 27. PMID: 30587184
Article Published Date : Dec 26, 2018
Study Type : In Vitro Study
Additional Links
Substances : Terminalia, Triphala
Diseases : Colorectal Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
Additional Keywords : Plant Extracts
[+]

Identification of bioactive molecules from Triphala as potential inhibitors of SARS-CoV-2 main protease.Mar 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J King Saud Univ Sci. 2022 Apr ;34(3):101826. Epub 2022 Jan 10. PMID: 35035181
Article Published Date : Mar 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Triphala
Diseases : Coronavirus Infection
Pharmacological Actions : Antiviral Agents
[+]

Mangosteen and triphala had good antimicrobial action on the mono-species biofilm.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Endod J. 2022 03 ;7(1):58-66. PMID: 35353063
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Mangosteen, Triphala
Diseases : Candida Albicans
Pharmacological Actions : Antimicrobial
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation, Plant Extracts
[+]

Neuroprotective herbs for the management of Alzheimer's disease. Apr 07, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2021 Apr 8 ;11(4). Epub 2021 Apr 8. PMID: 33917843
Article Published Date : Apr 07, 2021
Study Type : Review
Additional Links
Substances : Ashwagandha, Bacopa, Cat's Claw, Ginkgo biloba, Gotu Kola, Lion's Mane (Hericium Erinaceus), Saffron, Triphala, Turmeric
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Oxidative stress and cancer: chemopreventive and therapeutic role of triphala.Jan 12, 2020

Pubmed Data : Antioxidants (Basel). 2020 Jan 13 ;9(1). Epub 2020 Jan 13. PMID: 31941067
Article Published Date : Jan 12, 2020
Study Type : Review
Additional Links
Substances : Triphala
Diseases : Cancers: All, Oxidative Stress
Pharmacological Actions : Antioxidants, Chemopreventive, Chemotherapeutic, Immunomodulatory, Radioprotective
[+]

This review focuses on the immunomodulatory potential of the polyherbal preparation of triphala and its three constituents.Oct 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Pharm Sci. 2014 Nov-Dec;76(6):467-75. PMID: 25593379
Article Published Date : Oct 31, 2014
Study Type : Review
Additional Links
Substances : Triphala
Pharmacological Actions : Immunomodulatory
Additional Keywords : Ayurveda
[+]

Triphala can be effectively used to manage dental caries, gingival and periodontal diseases.May 11, 2015

Pubmed Data : Infect Disord Drug Targets. 2015 May 12. Epub 2015 May 12. PMID: 25966965
Article Published Date : May 11, 2015
Study Type : Review
Additional Links
Substances : Triphala
Diseases : Dental Caries, Dental Caries: Children, Gingivitis, Periodontal Diseases
Pharmacological Actions : Antimicrobial
[+]

Triphala in traditional ayurvedic medicine inhibits dengue virus infection in Huh7 hepatoma cells.Nov 27, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2021 Nov 28 ;14(12). Epub 2021 Nov 28. PMID: 34959637
Article Published Date : Nov 27, 2021
Study Type : In Vitro Study
Additional Links
Substances : Triphala
Diseases : Dengue
Pharmacological Actions : Antiviral Agents
[+]

Triphala inhibits two major enzymes that degrade the cartilage matrix.Jun 01, 2007

Pubmed Data : J Biosci. 2007 Jun;32(4):755-61. PMID: 17762148
Article Published Date : Jun 01, 2007
Additional Links
Substances : Triphala

Copyright: nilanewsom / 123RF Stock Photo

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