Ubiquinol

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33 Diseases Researched for Ubiquinol
NameACCKFocus
Oxidative Stress431Locked
Heart Failure220Locked
Sperm Quality: Low220Locked
Inflammation414Locked
Asthenozoospermia110Locked
C-Reactive Protein110Locked
Cholesterol: LDL/HDL ratio110Locked
Cholesterol: Oxidation110Locked
Chronic Fatigue Syndrome110Locked
Cognitive Decline/Dysfunction110Locked
Congestive Heart Failure110Locked
Diabetes Mellitus: Type 2110Locked
Diabetes: Glycation/A1C110Locked
Diabetic Polyneuropathy110Locked
Dry Mouth110Locked
High Cholesterol110Locked
Infertility: Male110Locked
Lipid Peroxidation110Locked
Multiple System Atrophy110Locked
Prenatal Nutrition 110Locked
Trisomy 21110Locked
Lipopolysaccharide-Induced Toxicity33Locked
Aging12Locked
Antiphospholipid Syndrome12Locked
Brain Injury: Traumatic12Locked
Endothelial Dysfunction12Locked
Kidney Diseases12Locked
Nephropathy12Locked
Parkinson's Disease12Locked
Traumatic Brain Injury12Locked
Ulcerative Colitis12Locked
Gingivitis11Locked
Periodontal Diseases11Locked
11 Pharmacological Actions Researched for Ubiquinol
NameACCKFocus
Antioxidants744Locked
Neuroprotective Agents416Locked
Anti-Inflammatory Agents413Locked
Cardiotonic Agents110Locked
Fertility Agents: Male110Locked
Interleukin-6 Downregulation110Locked
Neuritogenic110Locked
Renoprotective12Locked
Monocyte chemotattractant protein-1 (MCP-1) Inhibitor11Locked
RANTES (CCL5) Inhibitor11Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor11Locked
Related Topics

Ubiquinol is a Sub of the following Topic

View the Evidence:
39 Abstracts with Ubiquinol Research

[+]

A pilot clinical study of liquid ubiquinol supplementation on cardiac function in pediatric dilated cardiomyopathy.Nov 06, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Nov 7 ;10(11). Epub 2018 Nov 7. PMID: 30405022
Article Published Date : Nov 06, 2018
Study Type : Human Study
Additional Links
Substances : Ubiquinol
Diseases : Cardiomyopathy
Pharmacological Actions : Cardioprotective
[+]

Beneficial effect of ubiquinol on hematological and inflammatory signaling during exercise.Feb 05, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Feb 6 ;12(2). Epub 2020 Feb 6. PMID: 32041223
Article Published Date : Feb 05, 2020
Study Type : Human Study
Additional Links
Substances : Ubiquinol
Diseases : Inflammation, Muscle Damage: Exercise-Induced
Therapeutic Actions : Exercise
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Coenzyme Q10 (ubiquinol-10) supplementation improves oxidative imbalance in children with trisomy 21.Dec 01, 2007

Pubmed Data : Pediatr Neurol. 2007 Dec;37(6):398-403. PMID: 18021919
Article Published Date : Dec 01, 2007
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10, Ubiquinol
Diseases : Trisomy 21
[+]

Coenzyme Q10 improves sperm kinetic features in patients with idiopathic asthenozoospermia.Jul 01, 2009

Pubmed Data : J Endocrinol Invest. 2009 Jul;32(7):626-32. Epub 2009 May 21. PMID: 19509475
Article Published Date : Jul 01, 2009
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10, Ubiquinol
Diseases : Asthenozoospermia, Sperm Quality: Low
[+]

Coenzyme Q10 redox state predicts the concentration of c-reactive protein.Feb 22, 2016

Pubmed Data : Biofactors. 2016 Feb 23. Epub 2016 Feb 23. PMID: 26910885
Article Published Date : Feb 22, 2016
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10, Ubiquinol
Diseases : C-Reactive Protein, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Coenzyme Q10 supplementation improves salivary secretion associated with dry mouth.Mar 22, 2011

Pubmed Data : Clin Biochem. 2011 Mar 22. Epub 2011 Mar 22. PMID: 21406193
Article Published Date : Mar 22, 2011
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10, Ubiquinol
Diseases : Dry Mouth
[+]

Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation.Jun 26, 1992

Pubmed Data : Biochim Biophys Acta. 1992 Jun 26;1126(3):247-54. PMID: 1637852
Article Published Date : Jun 26, 1992
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10, Ubiquinol
Diseases : Cholesterol: Oxidation, Oxidative Stress
[+]

Foetuses are under greater oxidative stress than their mothers, as measured by the respective levels of oxidized and reduced conezyme Q10.Nov 01, 2010

Pubmed Data : Free Radic Res. 2010 Nov;44(11):1338-44. PMID: 20815779
Article Published Date : Nov 01, 2010
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10, Ubiquinol
Diseases : Prenatal Nutrition
[+]

Oral intake of liquid ubiquinol might benefit type 2 diabetes patients by increasing antioxidant enzyme activity levelsDec 31, 2017

Pubmed Data : Br J Nutr. 2018 07 ;120(1):57-63. PMID: 29936921
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Ubiquinol
Diseases : Diabetes: Oxidative Stress, Diabetes Mellitus: Type 2, Hypertension
Pharmacological Actions : Antioxidants
[+]

Short-term ubiquinol supplementation reduces oxidative stress associated with strenuous exercise.May 18, 2016

Pubmed Data : Biofactors. 2016 May 19. Epub 2016 May 19. PMID: 27193497
Article Published Date : May 18, 2016
Study Type : Human Study
Additional Links
Substances : Ubiquinol
Diseases : Oxidative Stress
Therapeutic Actions : Exercise
Pharmacological Actions : Antioxidants
[+]

Short-term Ubiquinol-10 supplementation alleviates tissue damage in muscle and fatigue caused by strenuous exercise in male distance runners.Jan 30, 2020

Pubmed Data : Int J Vitam Nutr Res. 2020 Jan 31:1-10. Epub 2020 Jan 31. PMID: 32003645
Article Published Date : Jan 30, 2020
Study Type : Human Study
Additional Links
Substances : Ubiquinol
Diseases : Muscle Damage: Exercise-Induced
Therapeutic Actions : Exercise: Running
Pharmacological Actions : Enzyme Inhibitors
[+]

Supplemental ubiquinol has therapeutic effects in advanced congestive heart failure patients.Jan 01, 2008

Pubmed Data : Biofactors. 2008;32(1-4):119-28. PMID: 19096107
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10, Ubiquinol
Diseases : Congestive Heart Failure, Heart Failure
Pharmacological Actions : Cardiotonic Agents
[+]

Supplementation with ubiquinol-10 for 12 weeks is effective for improving several chronic fatigue syndrome symptoms.Apr 28, 2016

Pubmed Data : Biofactors. 2016 Apr 29. Epub 2016 Apr 29. PMID: 27125909
Article Published Date : Apr 28, 2016
Study Type : Human Study
Additional Links
Substances : Ubiquinol
Diseases : Chronic Fatigue Syndrome, Cognitive Decline/Dysfunction
[+]

The reduced form of coenzyme Q10 improves glycemic control in patients with type 2 diabetes.Aug 07, 2012

Pubmed Data : Biofactors. 2012 Aug 8. Epub 2012 Aug 8. PMID: 22887051
Article Published Date : Aug 07, 2012
Study Type : Human Study
Additional Links
Substances : Ubiquinol
Diseases : Diabetes: Glycation/A1C, Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants
[+]

These results suggests the therapeutic potential of ubiquinol for patients with multiple system atrophy with COQ2 mutations.May 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cerebellum. 2017 Jun ;16(3):664-672. PMID: 28150130
Article Published Date : May 31, 2017
Study Type : Human Study
Additional Links
Substances : Ubiquinol
Diseases : Multiple System Atrophy
Pharmacological Actions : Neuroprotective Agents
[+]

Twelve weeks treatment with ubiquinone improves clinical outcomes and nerve conduction parameters of diabetic polyneuropathy.Jun 30, 2012

Pubmed Data : J Diabetes Complications. 2012 Jul-Aug;26(4):352-8. Epub 2012 May 16. PMID: 22595020
Article Published Date : Jun 30, 2012
Study Type : Human Study
Additional Links
Substances : Ubiquinol
Diseases : Diabetic Polyneuropathy, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Antioxidants, Neuritogenic
[+]

Ubiquinol + L-carnitine can cause a significant reduction in the pro-inflammatory cytokines in patients with heart failure.Aug 01, 2007

Pubmed Data : Acta Cardiol. 2007 Aug;62(4):349-54. PMID: 17824295
Article Published Date : Aug 01, 2007
Study Type : Human Study
Additional Links
Substances : Carnitine, Coenzyme Q10, Ubiquinol
Diseases : Heart Failure
Pharmacological Actions : Interleukin-6 Downregulation
[+]

Ubiquinol improves endothelial function in patients with heart failure with reduced ejection fraction.Nov 11, 2019

Pubmed Data : Am J Cardiovasc Drugs. 2019 Nov 12. Epub 2019 Nov 12. PMID: 31713723
Article Published Date : Nov 11, 2019
Study Type : Human Study
Additional Links
Substances : Ubiquinol
Diseases : Endothelial Dysfunction, Heart Failure
Pharmacological Actions : Cardioprotective
[+]

Ubiquinol induces characteristic gene expression patterns, which are translated into reduced LDL cholesterol levels and altered parameters of erythropoiesis in humans.Jan 01, 2011

Pubmed Data : IUBMB Life. 2011 Jan;63(1):42-8. PMID: 21280176
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Substances : Ubiquinol
Diseases : Cholesterol: LDL/HDL ratio, High Cholesterol
[+]

Ubiquinol is superior to ubiquinone to enhance Coenzyme Q10 status in older men.Nov 13, 2018

Pubmed Data : Food Funct. 2018 Nov 14 ;9(11):5653-5659. PMID: 30302465
Article Published Date : Nov 13, 2018
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10, Ubiquinol
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation
[+]

Ubiquinol supplementation alters exercise induced fatigue by increasing lipid utilization.Oct 22, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Oct 23 ;11(11). Epub 2019 Oct 23. PMID: 31652711
Article Published Date : Oct 22, 2019
Study Type : Human Study
Additional Links
Substances : Ubiquinol
Diseases : Fatigue: Excercise-Induced
Therapeutic Actions : Exercise
[+]

Ubiquinol was significantly effective in men with unexplained oligoasthenoteratozoospermia for improving density, motility and morphology of sperm. Jul 31, 2012

Pubmed Data : J Urol. 2012 Aug ;188(2):526-31. Epub 2012 Jun 15. PMID: 22704112
Article Published Date : Jul 31, 2012
Study Type : Human Study
Additional Links
Substances : Ubiquinol
Diseases : Infertility: Male, Sperm Quality: Low
Pharmacological Actions : Antioxidants, Fertility Agents: Male
[+]

Administering ubiquinol 30 min before traumatic brain injury significantly affected cerebral gene expression profiles.Jun 30, 2017

Pubmed Data : Nurs Outlook. 2017 Jul 1. Epub 2017 Jul 1. PMID: 28755974
Article Published Date : Jun 30, 2017
Study Type : Animal Study
Additional Links
Substances : Ubiquinol
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Gene Expression Regulation
[+]

Aloe vera and ubiqinol have a protective and healing effect on experimental ulcerative colitis in rats. Dec 15, 2001

Pubmed Data : Lancet. 2001 Dec 15;358(9298):2026-33. PMID: 14695941
Article Published Date : Dec 15, 2001
Study Type : Animal Study
Additional Links
Substances : Aloe Vera, Ubiquinol
Diseases : Ulcerative Colitis
Pharmacological Actions : Antioxidants
[+]

Coenzyme Q10 has a neuroprotective effect in an experimental model of Parkinson's disease.Mar 01, 2008

Pubmed Data : J Neurochem. 2008 Mar;104(6):1613-21. Epub 2007 Oct 31. PMID: 17973981
Article Published Date : Mar 01, 2008
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10, Ubiquinol
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Evaluation of the cardioprotective effect of ubiquinol on the model of reperfusion injury of rat myocardium.Feb 28, 2018

Pubmed Data : Biomed Khim. 2018 Mar ;64(2):188-194. PMID: 29723149
Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : Ubiquinol
Diseases : Myocardial Ischemia
Pharmacological Actions : Cardioprotective
[+]

The reduced form of coenzyme Q10 (ubiquinol) has distinctly different effects on cholesterol metabolism than oxidized coenzyme Q10 (ubiquinone)Nov 17, 2010

Pubmed Data : IUBMB Life. 2010 Nov 17. Epub 2010 Nov 17. PMID: 21086475
Article Published Date : Nov 17, 2010
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10, Ubiquinol
Additional Keywords : Nutrient Differences: Reduced/Oxidized Forms
[+]

The reduced form of coenzyme Q10 (ubiquinol) is more effective at decelerating aging than the oxidized form (ubiquinone). Jun 01, 2010

Pubmed Data : Mol Nutr Food Res. 2010 Jun;54(6):805-15. PMID: 19960455
Article Published Date : Jun 01, 2010
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10, Ubiquinol
Diseases : Aging
Additional Keywords : Bioavailability, Nutrient Differences: Reduced/Oxidized Forms
[+]

The reduced form of coenzyme Q10 may prevent or minimize cyclosporine nephrotoxicity by an antioxidant effect.Nov 27, 2012

Pubmed Data : Exp Clin Transplant. 2012 Nov 28. Epub 2012 Nov 28. PMID: 23194328
Article Published Date : Nov 27, 2012
Study Type : Animal Study
Additional Links
Substances : Ubiquinol
Diseases : Nephropathy
Pharmacological Actions : Renoprotective
Problem Substances : Cyclosporine
Adverse Pharmacological Actions : Nephrotoxic
[+]

This highlights the potential of ubiquinol to modulate the overexpression of inflammatory and thrombotic risk markers in antiphospholipid syndrome.Sep 30, 2017

Pubmed Data : Arterioscler Thromb Vasc Biol. 2017 Oct ;37(10):1923-1932. Epub 2017 Jul 6. PMID: 28684614
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Ubiquinol
Diseases : Antiphospholipid Syndrome, Endothelial Dysfunction, Inflammation
[+]

Ubiquinol preserves mitochondria and reduces cellular injury severity after traumatic brain injury.Jan 29, 2018

Pubmed Data : J Neurosci Res. 2018 Jan 30. Epub 2018 Jan 30. PMID: 29380912
Article Published Date : Jan 29, 2018
Study Type : Animal Study
Additional Links
Substances : Ubiquinol
Diseases : Traumatic Brain Injury
Pharmacological Actions : Neuroprotective Agents
[+]

Ubiquinol promotes retinal ganglion cell survival and blocks the apoptotic pathway in ischemic retinal degeneration.Jan 17, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biochem Biophys Res Commun. 2018 09 18 ;503(4):2639-2645. Epub 2018 Aug 11. PMID: 30107910
Article Published Date : Jan 17, 2018
Study Type : Animal Study
Additional Links
Substances : Ubiquinol
Diseases : Glaucoma, Retinal Degeneration: Light-Induced
Pharmacological Actions : Anti-Apoptotic, Antioxidants
[+]

Ubiquinol, the reduced form of CoQ10, effectively ameliorates renal function. Sep 28, 2010

Pubmed Data : Clin Exp Nephrol. 2010 Sep 28. Epub 2010 Sep 28. PMID: 20878200
Article Published Date : Sep 28, 2010
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10, Ubiquinol
Diseases : Kidney Diseases
[+]

Coenzyme Q10 may suppress advanced periodontal inflammation.May 01, 2010

Pubmed Data : Int Immunopharmacol. 2010 May;10(5):605-10. Epub 2010 Feb 23. PMID: 21189900
Article Published Date : May 01, 2010
Study Type : Review
Additional Links
Substances : Coenzyme Q10, Ubiquinol
Diseases : Gingivitis, Periodontal Diseases
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Ubiquinol down-regulates lipopolysaccharide-sensitive genes in human monocytic THP-1 cells.Apr 01, 2011

Pubmed Data : J Med Food. 2011 Apr;14(4):391-7. Epub 2011 Mar 3. PMID: 21370964
Article Published Date : Apr 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Ubiquinol
Diseases : Lipopolysaccharide-Induced Toxicity
[+]

Ubiquinol has anti-inflammatory properties on various proinflammatory cytokines and chemokines.Jan 01, 2009

Pubmed Data : J Clin Biochem Nutr. 2009 Jan;44(1):62-6. Epub 2008 Dec 27. PMID: 19177190
Article Published Date : Jan 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Coenzyme Q10, Ubiquinol
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Monocyte chemotattractant protein-1 (MCP-1) Inhibitor, RANTES (CCL5) Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ubiquinol is capable of regenerating vitamin E. Jun 01, 2005

Pubmed Data : J Allergy Clin Immunol. 2005 Jun;115(6):1176-83. PMID: 20415458
Article Published Date : Jun 01, 2005
Study Type : Commentary
Additional Links
Substances : Ubiquinol, Vitamin E
Additional Keywords : Natural Substance Synergy
[+]

Ubiquinol may have anti-inflammatory properties.Jan 01, 2009

Pubmed Data : Mediators Inflamm. 2009;2009:415437. Epub 2009 Apr 16. PMID: 19390647
Article Published Date : Jan 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Ubiquinol
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Ubiquinone and ubiquinol have differing role in reducing oxidative stress.Jan 01, 2009

Pubmed Data : Free Radic Biol Med. 2009 Jan 1;46(1):105-9. Epub 2008 Oct 14. PMID: 18977291
Article Published Date : Jan 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Coenzyme Q10, Ubiquinol
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Nutrient Differences: Reduced/Oxidized Forms

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