Ursolic Acid

Name	AC	CK
Colorectal Cancer	11	13
Breast Cancer	10	10
Oxidative Stress	8	10
Cancers: All	7	8
Cancers: Drug Resistant	7	7
Liver Fibrosis	4	7
Ovarian Cancer	3	7
Alzheimer's Disease	4	6
Colon Cancer	6	6
Depression	4	6
Diabetes Mellitus: Type 2	3	6
Diabetic Nephropathy	3	6
Gastric Cancer	4	6
High Fat Diet	3	6
Insulin Resistance	3	6
Obesity	3	6
Anxiety	3	5
Breast Cancer: Triple Negative	5	5
Cerebral Ischemia	3	5
Chemically-Induced Liver Damage	3	5
Liver Cancer	5	5
Osteoporosis	3	5
Parkinson's Disease	3	5
Dysbiosis	2	4
Emphysema: Pulmonary	2	4
Lung Cancer	3	4
Muscle Atrophy	2	4
Nonalcoholic fatty liver disease (NAFLD)	2	4
Prostate Cancer	3	4
Smoking	2	4
Cervical Cancer	2	3
DNA damage	3	3
Gallbladder Cancer	2	3
Inflammation	2	3
Kidney Damage	2	3
Osteosarcoma	3	3
Skin Cancer	2	3
Aging	1	2
Air Pollution Linked Toxicity	1	2
Aortic Aneurysm	1	2
Arteriosclerosis	1	2
Arthritis	1	2
Atherosclerosis	1	2
Cancer Metastasis	2	2
Carcinoma: Non-Small-Cell Lung	2	2
Cardiomyopathy	1	2
Chemotherapy and Radiation Toxicity	1	2
Chemotherapy-Induced Toxicity: Doxorubicin	1	2
Chronic Obstructive Pulmonary Disease	1	2
Diabetic Complications	1	2
Fatty Liver	1	2
Gastrointestinal Diseases	1	2
Gestational Diabetes	1	2
Hepatic Steatosis	1	2
Hyperalgesia	1	2
Hypercholesterolemia	1	2
Hyperinsulinism	1	2
Inflammatory Bowel Diseases	1	2
Ischemia	1	2
Liver Cirrhosis	1	2
Lung Injury: Smoke-Induced	1	2
Mycobacterium Tuberculosis	2	2
Myocardial Fibrosis	1	2
Myocardial Infarction	1	2
Neurodegenerative Diseases	1	2
Non-Small-Cell Lung Carcinoma	1	2
Oral Cancer	2	2
Pulmonary Emphysema	1	2
Restenosis	1	2
Sciatic Nerve Crush Injury	1	2
Sciatica	1	2
Spinal Cord Injuries	1	2
Streptococcus Infections	2	2
Thyroid Cancer	1	2
Ulcerative Colitis	1	2
Wound Healing	1	2
Aflatoxicosis	1	1
Autoimmune Thyroiditis	1	1
Bacillus Cereus infection	1	1
Breast Cancer: estrogen receptor alpha-positive	1	1
Cognitive Decline/Dysfunction	1	1
Dental Caries	1	1
Endometrial Cancer	1	1
Enterobacteriaceae Infections	1	1
Enterococcus Infections	1	1
Enterovirus 71	1	1
Esophageal Cancer	1	1
Glioblastoma	1	1
Hearing Loss	1	1
Hepatitis B	1	1
Hepatitis C	1	1
Herpes Simplex Virus Type 1	1	1
Herpes Simplex Virus Type 2	1	1
High Sugar Diet	1	1
Human Papillomavirus (HPV)	1	1
Hydrogen Peroxide Induced Toxicity	1	1
Infection: Antibiotic Resistant	1	1
Kidney Damage: Chemically-Induced	1	1
Klebsiella Infections	1	1
Klesiella Pneumonia Infection	1	1
Leishmaniasis	1	1
Leukemia: Chronic myelogenous leukemia (CML)	1	1
Malaria	1	1
Melanoma	1	1
Mesothelioma	1	1
Multiple Myeloma	1	1
Rotavirus Infections	1	1
Sarcomas	1	1
Staphylococcus aureus infection	1	1
Staphylococcus aureus: Methicillin-resistant (MRSA)	1	1
Steptococcus Mutans Infections	1	1
Toxoplasma gondii Infection	1	1
Toxoplasmosis	1	1
Tuberculosis	1	1

Name	AC	CK
Antiproliferative	40	52
Apoptotic	37	47
Anti-Inflammatory Agents	25	40
Antioxidants	19	31
Neuroprotective Agents	10	17
Chemotherapeutic	12	15
Hepatoprotective	8	14
Chemosensitizer	9	13
Anti-metastatic	11	12
NF-kappaB Inhibitor	10	12
Cell cycle arrest	8	9
Chemopreventive	7	8
Gastrointestinal Agents	4	8
Anti-Apoptotic	4	7
Anti-Fibrotic	4	7
MicroRNA modulator	6	7
Anticarcinogenic Agents	4	6
Cardioprotective	3	6
Gastroprotective	3	6
Renoprotective	4	6
Antidepressive Agents	3	5
Interleukin-1 beta downregulation	3	5
Osteoprotective	3	5
Anti-Anxiety Agents	2	4
Antiviral Agents	4	4
Autophagy Up-regulation	4	4
Cyclooxygenase 2 Inhibitors	4	4
Enzyme Activators	2	4
Hypoglycemic Agents	2	4
Immunomodulatory	3	4
Interleukin-18 down-regulation	2	4
Interleukin-6 Downregulation	3	4
Neurogenesis	2	4
Antimicrobial	3	3
Caspase-3 Activation	2	3
Caspase-9 Activation	2	3
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	3	3
Matrix metalloproteinase-9 (MMP-9) inhibitor	2	3
STAT3 Inhibitor	3	3
Tumor Necrosis Factor (TNF) Alpha Inhibitor	2	3
Alpha-glucosidase inhibitor	1	2
Analgesics	1	2
Angiogenesis Inhibitors	1	2
Anti-Bacterial Agents	2	2
Anti-atherogenic	1	2
Anticholesteremic Agents	1	2
Antineoplastic Agents	2	2
Antiparasitic Agents	2	2
Chemoprotective Agents	1	2
Cyclin D1 Down-Regulation	2	2
Genoprotective	2	2
Insulin-releasing	1	2
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	2
Nrf2 activation	1	2
Radioprotective	1	2
Radiosensitizer	2	2
Vascular Endothelial Growth Factor Inhibitors	2	2
Wnt/β-catenin signaling pathway modulation	2	2
Antimalarials	1	1
Antimutagenic Agents	1	1
Antimycobacterial	1	1
Autophagy Inhibitors	1	1
Bcl-2 protein down-regulation	1	1
Cytoprotective	1	1
DNA Repair Up-regulation	1	1
Estrogen Receptor Modulators	1	1
Heat Shock Protein Down-Regulation	1	1
Leishmanicidal	1	1
Multidrug Resistance Gene Modulators	1	1
Nitric Oxide Enhancer	1	1
P21 Activation	1	1
Superoxide Scavenger	1	1

[+]

Ursolic acid could affect the proliferation and apoptosis of human ovarian cancer stem-like cells and it is a potent anti-ovarian cancer agent.Oct 31, 2015

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Pubmed Data : Oncol Rep. 2015 Nov ;34(5):2375-84. Epub 2015 Aug 20. PMID: 26323892

Article Published Date : Oct 31, 2015

Study Type : Human In Vitro

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Substances : Ursolic Acid

Diseases : Ovarian Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer

Additional Keywords : Cancer Stem Cells

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Ursolic acid enhances the sensitivity of MCF-7 and MDA-MB-231 cells to epirubicin.May 24, 2022

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Pubmed Data : Eur J Pharmacol. 2015 Jul 5 ;758:171-6. Epub 2015 Apr 8. PMID: 25861934

Article Published Date : Jul 04, 2015

Study Type : Animal Study

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Substances : Ursolic Acid

Diseases : Anxiety

Pharmacological Actions : Anti-Anxiety Agents

[+]

C. officinalis may be used as a valuable food supplement for the treatment of diabetes mellitus.Jan 31, 2016

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Pubmed Data : Phytother Res. 2016 Feb ;30(2):283-91. Epub 2015 Dec 1. PMID: 26619955

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Pubmed Data : IUBMB Life. 2019 Dec 16. Epub 2019 Dec 16. PMID: 31840927

Article Published Date : Dec 15, 2019

Study Type : Animal Study

Additional Links

Substances : Ursolic Acid

Diseases : Air Pollution Linked Toxicity, Chronic Obstructive Pulmonary Disease

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

Protective effect of ursolic acid on the intestinal mucosal barrier in a rat model of liver fibrosis.Dec 31, 2018

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Pubmed Data : Phytomedicine. 2021 Jan 31 ;83:153490. Epub 2021 Jan 31. PMID: 33601255

Article Published Date : Jan 30, 2021

Study Type : Animal Study

Additional Links

Substances : Rosmarinic acid, Ursolic Acid

Diseases : Alzheimer's Disease

Pharmacological Actions : Neurogenesis, Neuroprotective Agents

[+]

Solubilization and delivery of Ursolic-acid for modulating tumor microenvironment and regulatory T cell activities in cancer immunotherapy.Jan 07, 2020

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Pubmed Data : J Control Release. 2020 Jan 8 ;320:168-178. Epub 2020 Jan 8. PMID: 31926193

Article Published Date : Jan 07, 2020

Study Type : Animal Study

Additional Links

Substances : Ursolic Acid

Diseases : Cancers: All

Pharmacological Actions : Antiproliferative , Chemotherapeutic, Immunomodulatory

Additional Keywords : Tumor Microenvironment

[+]

Synergistic effect of ursolic acid and piperine in CCl 4 induced hepatotoxicity.Nov 30, 2021

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[+]

Ursolic acid administered after irradiation greatly improved acute irradiation-induced deficits in contextual learning and memory.May 31, 2017

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Pubmed Data : Physiol Behav. 2017 Jun 1 ;175:37-46. Epub 2017 Mar 22. PMID: 28341234

Article Published Date : May 31, 2017

Study Type : Animal Study

Additional Links

Substances : Ursolic Acid

Diseases : Chemotherapy and Radiation Toxicity

Pharmacological Actions : Neuroprotective Agents, Radioprotective

[+]

Ursolic acid alleviates airway-vessel remodeling and muscle consumption in cigarette smoke-induced emphysema rats.Jun 05, 2019

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[+]

Ursolic acid enhances autophagic clearance and ameliorates motor and non-motor symptoms in Parkinson's disease model.Sep 21, 2022

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Pubmed Data : Acta Pharmacol Sin. 2022 Sep 22. Epub 2022 Sep 22. PMID: 36138143

Article Published Date : Sep 21, 2022

Study Type : Animal Study

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Substances : Ursolic Acid

Diseases : Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

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Pubmed Data : Neural Regen Res. 2013 Sep 25 ;8(27):2510-9. PMID: 25206561

Pubmed Data : Atherosclerosis. 2006 Jan;184(1):53-62. PMID: 15922347

Article Published Date : Jan 01, 2006

Study Type : Animal Study

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Substances : Ursolic Acid

Diseases : Arteriosclerosis, Restenosis

[+]

Ursolic acid may ameliorate the deleterious effects of diet-induced obesity and associated complications such as hepatic fibrosis.Nov 08, 2018

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Pubmed Data : Nutrients. 2018 Nov 9 ;10(11). Epub 2018 Nov 9. PMID: 30423963

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Pubmed Data : Chin J Integr Med. 2019 Mar ;25(3):210-215. Epub 2018 Aug 30. PMID: 30159645

Article Published Date : Feb 28, 2019

Study Type : Animal Study

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Substances : Ursolic Acid

Diseases : Osteoporosis

Pharmacological Actions : Osteoprotective

Problem Substances : Retinoic Acid

[+]

Ursolic acid nanoparticles inhibited cervical cancer cell proliferation via apoptosis induction.Feb 21, 2017

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Pubmed Data : Int J Oncol. 2017 Feb 22. Epub 2017 Feb 22. PMID: 28259944

Article Published Date : Feb 21, 2017

Study Type : Animal Study, In Vitro Study

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Substances : Ursolic Acid

Diseases : Cervical Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

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Pubmed Data : J Ethnopharmacol. 2021 Nov 15 ;280:114410. Epub 2021 Jul 15. PMID: 34273447

Article Published Date : Nov 14, 2021

Study Type : Review

Additional Links

Substances : Berberine, Tannic Acid, Ursolic Acid, Xanthohumol

Diseases : Obesity

Additional Keywords : Anti-Obesity Agents

[+]

Ameliorative effect of ursolic acid on ochratoxin A-induced renal cytotoxicity.Jul 25, 2019

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Pubmed Data : Toxicon. 2019 Jul 26. Epub 2019 Jul 26. PMID: 31356822

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Pubmed Data : J BUON. 2020 Mar-Apr;25(2):750-756. PMID: 32521863

Article Published Date : Feb 29, 2020

Study Type : In Vitro Study

Additional Links

Substances : Ursolic Acid

Diseases : Ovarian Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

[+]

Anticancer effect of ursolic acid via mitochondria-dependent pathways.May 31, 2019

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Pubmed Data : Biofactors. 2022 Dec 23. Epub 2022 Dec 23. PMID: 36564953

Article Published Date : Dec 22, 2022

Study Type : In Vitro Study

Additional Links

Substances : Carnosic Acid, Carnosol, Rosmarinic acid, Ursolic Acid

Diseases : Respiratory Diseases

Pharmacological Actions : Anti-Inflammatory Agents, interleukin-13 down-regulation, Interleukin-4 downregulation, Interleukin-5 downregulation

[+]

Evidence of the beneficial effects of ursolic acid against lung cancer.Nov 01, 2022

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Pubmed Data : Molecules. 2022 Nov 2 ;27(21). Epub 2022 Nov 2. PMID: 36364289

Article Published Date : Nov 01, 2022

Study Type : Review

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Substances : Ursolic Acid

Diseases : Lung Cancer

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Antiproliferative

[+]

Inhibition of colorectal cancer tumorigenesis by ursolic acid and doxorubicin.Dec 31, 2022

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Pubmed Data : Cancer Lett. 2009 Aug 28;281(2):162-70. Epub 2009 Apr 2. PMID: 19344998

Article Published Date : Aug 28, 2009

Study Type : In Vitro Study

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Substances : Luteolin, Quercetin, Ursolic Acid

Diseases : Colorectal Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Major triterpenoids in Chinese hawthorn inhibited proliferation and induced apoptosis in MDA-MB-231 cancer cells.Jan 31, 2017

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Pubmed Data : Food Chem Toxicol. 2017 Feb ;100:149-160. Epub 2016 Dec 23. PMID: 28025124

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Pubmed Data : Phytother Res. 2007 Jun;21(6):558-61. PMID: 17295383

Article Published Date : Jun 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Motherwort, Ursolic Acid

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants, Superoxide Scavenger

Additional Keywords : Substances that are Linked

[+]

Oncolytic measles virus and ursolic acid-based chemovirotherapy for further development as a treatment strategy against breast cancer.Jan 03, 2021

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Pubmed Data : Cancers (Basel). 2021 Jan 4 ;13(1). Epub 2021 Jan 4. PMID: 33406633

Article Published Date : Jan 03, 2021

Study Type : In Vitro Study

Additional Links

Substances : Ursolic Acid, Viruses: Beneficial

Diseases : Breast Cancer

Pharmacological Actions : Chemotherapeutic

Additional Keywords : Chemovirotherapy, Health Benefits of Measles Infection

[+]

P-coumaric acid and ursolic acid from Corni fructus attenuated β-amyloid(25-35)-induced toxicity.May 27, 2014

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Pubmed Data : J Agric Food Chem. 2014 May 28 ;62(21):4911-6. Epub 2014 May 19. PMID: 24815946

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Pubmed Data : Drug Chem Toxicol. 2016 Jul 27:1-7. Epub 2016 Jul 27. PMID: 27461151

Article Published Date : Jul 26, 2016

Study Type : In Vitro Study

Additional Links

Substances : Puerarin, Ursolic Acid

Diseases : DNA damage, Hydrogen Peroxide Induced Toxicity

Pharmacological Actions : Antioxidants, Genoprotective

[+]

Reactive oxygen species-mediated autophagy by ursolic acid inhibits growth and metastasis of esophageal cancer cells.Dec 09, 2020

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Pubmed Data : J Cancer Prev. 2015 Dec ;20(4):223-31. Epub 2015 Dec 30. PMID: 26734584

Article Published Date : Nov 30, 2015

Study Type : Review

Additional Links

Substances : Capsaicin, Curcumin, Genipin, Lycopene, Ursolic Acid

Diseases : Breast Cancer

Pharmacological Actions : Chemopreventive

[+]

The results suggest these compounds show potential for further optimization as antiviral candidates for treatment of EV71 infections.Dec 31, 2013

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Ursolic acid and acteoside regulates multiple targets, bioprocesses and signal pathways against Alzheimer's disease pathogenesis.Nov 30, 2022

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Pubmed Data : Med Sci Monit. 2019 Feb 17 ;25:1283-1290. Epub 2019 Feb 17. PMID: 30772887

Article Published Date : Feb 16, 2019

Study Type : In Vitro Study

Additional Links

Substances : Ursolic Acid

Diseases : Cancer Metastasis, Melanoma

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Bcl-2 protein down-regulation

[+]

Ursolic acid appears to be an effective therapeutic agent against colon cancer.Aug 31, 2019

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Pubmed Data : Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2017 Nov 1 ;31(11):1371-1376. PMID: 29798594

Article Published Date : Oct 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Ursolic Acid

Diseases : Osteosarcoma

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Cyclin D1 Down-Regulation

[+]

Ursolic acid can inhibit the growth and metastasis of colorectal cancer.Sep 14, 2012

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Pubmed Data : Clin Cancer Res. 2012 Sep 15 ;18(18):4942-53. Epub 2012 Jul 25. PMID: 22832932

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Pubmed Data : PLoS One. 2015;10(7):e0133169. Epub 2015 Jul 15. PMID: 26177078

Article Published Date : Dec 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Ursolic Acid

Diseases : Gastric Cancer

Pharmacological Actions : Antiproliferative , Cell cycle arrest, Radiosensitizer

[+]

Ursolic acid decreases the proliferation of MCF-7 cell-derived breast cancer stem-like cells.Dec 30, 2021

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Pubmed Data : Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2018 Nov 28 ;43(11):1188-1193. PMID: 30643062

Article Published Date : Nov 27, 2018

Study Type : In Vitro Study

Additional Links

Substances : Ursolic Acid

Diseases : Cancer Metastasis, Liver Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative

[+]

Ursolic acid exhibited antibiofilm activity against oral pathogenic bacteria and had the potential to be used in dental caries treatment.Mar 14, 2021

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Pubmed Data : Oncol Lett. 2019 Sep ;18(3):2628-2638. Epub 2019 Jul 4. PMID: 31404298

Article Published Date : Aug 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Ursolic Acid

Diseases : Osteosarcoma

Pharmacological Actions : Anti-metastatic, Antiproliferative

[+]

Pubmed Data : Br J Nutr. 2009 Apr;101(8):1145-9. PMID: 15583801

Article Published Date : Apr 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Ursolic Acid

Diseases : Endometrial Cancer

Pharmacological Actions : Apoptotic

[+]

Ursolic acid inhibited the proliferation of A549 and H460 cells in a concentration-dependent manner.Mar 12, 2021

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Pubmed Data : Cytokine. 2019 Jul 11 ;123:154726. Epub 2019 Jul 11. PMID: 31302461

Article Published Date : Jul 10, 2019

Study Type : In Vitro Study

Additional Links

Substances : Ursolic Acid

Diseases : Kidney Damage

Pharmacological Actions : Anti-Inflammatory Agents, Autophagy Up-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Ursolic acid is a potential anticancer compound for breast cancer therapy.Mar 03, 2018

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Pubmed Data : Crit Rev Food Sci Nutr. 2018 Mar 4 ;58(4):568-574. Epub 2017 Oct 4. PMID: 27469428

Article Published Date : Mar 03, 2018

Study Type : In Vitro Study

Additional Links

Substances : Ursolic Acid

Diseases : Breast Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

[+]

Ursolic acid: a natural modulator of signaling networks in different cancers.Dec 09, 2022

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Pubmed Data : Molecules. 2019 Sep 23 ;24(19). Epub 2019 Sep 23. PMID: 31547522

Article Published Date : Sep 22, 2019

Study Type : In Vitro Study

Additional Links

Substances : Oleanolic acid, Ursolic Acid

Diseases : Lung Cancer

Pharmacological Actions : Autophagy Inhibitors, Chemotherapeutic

[+]

Ursolic and oleanolic acids: plant metabolites with neuroprotective potential.Apr 26, 2021

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Pubmed Data : Int J Mol Sci. 2021 Apr 27 ;22(9). Epub 2021 Apr 27. PMID: 33925641

Article Published Date : Apr 26, 2021

Study Type : Review

Additional Links

Substances : Oleanolic acid, Ursolic Acid

Diseases : Alzheimer's Disease, Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

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Ursolic acid could affect the proliferation and apoptosis of human ovarian cancer stem-like cells and it is a potent anti-ovarian cancer agent.Oct 31, 2015

Ursolic acid enhances the sensitivity of MCF-7 and MDA-MB-231 cells to epirubicin.May 24, 2022

Ursolic acid alleviates Kupffer cells pyroptosis in liver fibrosis.Nov 30, 2022

Ursolic acid restores sensitivity to gemcitabine.Jan 14, 2021

Anti-inflammatory activity of ursolic acid in MPTP-induced parkinsonian mouse model.Apr 22, 2019

Anti-obesity and anti-diabetic effect of ursolic acid.Feb 02, 2022

Anxiolytic-like effects of ursolic acid in mice.Jul 04, 2015

C. officinalis may be used as a valuable food supplement for the treatment of diabetes mellitus.Jan 31, 2016

Dietary ursolic acid improves health span and life span in male Drosophila melanogaster.Feb 28, 2019

Effects of ursolic acid on oxidative stress and inflammatory factors in a rat model of AR after PM2.5 exposure.Jul 06, 2022

Modulatory effect of ursolic acid on neurodegenerative activities in oxidative brain injury.Dec 22, 2020

Oleanolic acid and ursolic acid improve bone properties and calcium nalance and modulate vitamin D metabolism in aged female rats.Dec 31, 2017

Preventive effect of ursolic acid derivative on particulate matter 2.5-induced chronic obstructive pulmonary disease.Dec 15, 2019

Protective effect of ursolic acid on the intestinal mucosal barrier in a rat model of liver fibrosis.Dec 31, 2018

Protective mechanisms of loquat leaf extract and ursolic acid against diabetic pro-inflammation.Aug 12, 2022

Research advances in protective effects of ursolic acid and oleanolic acid against gastrointestinal diseases.Feb 19, 2021

Rosemary and its constituents carnosol and ursolic acid inhibit skin cancer formation. Feb 01, 1994

Rosmarinic acid and ursolic acid alleviate deficits in cognition, synaptic regulation and adult hippocampal neurogenesis.Jan 30, 2021

Solubilization and delivery of Ursolic-acid for modulating tumor microenvironment and regulatory T cell activities in cancer immunotherapy.Jan 07, 2020

Synergistic effect of ursolic acid and piperine in CCl 4 induced hepatotoxicity.Nov 30, 2021

Targeted delivery of ursolic acid and oleanolic acid to lungs in the form of an inhaler for the management of tuberculosis.Dec 31, 2021

The anti-arthritic effect of ursolic acid is comparable to ibuprofen in an animal model of arthritis, without causing gastric leasions. Oct 01, 2008

The combination of ursolic acid and empagliflozin relieves diabetic nephropathy.Oct 05, 2021

The combination treatment with ursolic acid and rosiglitazone ameliorated HFD-induced glucose intolerance and insulin resistance.May 31, 2016

The present findings indicated that ursolic acid may be a possible therapeutic agent against diabetic nephropathy.Oct 31, 2018

These data suggest that concurrent treatment with low-intensity exercise and ursolic acid is effective for atrophy-related physical dysfunctions.Jun 30, 2018

These results demonstrate a protective role of ursolic acid in ulcerative colitis.May 31, 2016

This work reveals the potential of ursolic acid as a promising treatment candidate for Parkinson's disease.Dec 11, 2015

Ursolic acid abrogates depressive-like behavior and hippocampal pro-apoptotic imbalance induced by chronic unpredictable stress.Jan 03, 2021

Ursolic acid accelerates paclitaxel-induced cell death in esophageal cancer cells.Oct 24, 2021

Ursolic acid administered after irradiation greatly improved acute irradiation-induced deficits in contextual learning and memory.May 31, 2017

Ursolic acid alleviates airway-vessel remodeling and muscle consumption in cigarette smoke-induced emphysema rats.Jun 05, 2019

Ursolic acid alleviates tetrandrine-induced hepatotoxicity.Aug 31, 2022

Ursolic acid ameliorated the severity of abdominal aortic aneurysms.Feb 14, 2018

Ursolic acid ameliorates adipose tissue insulin resistance in aged rats.Nov 30, 2021

Ursolic acid ameliorates amyloid β-induced pathological symptoms in Caenorhabditis elegans by activating the proteasome.Dec 31, 2021

Ursolic acid ameliorates inflammation in cerebral ischemia and reperfusion injury.Dec 31, 2017

Ursolic acid ameliorates spinal cord injury in mice by regulating gut microbiota.Dec 31, 2021

Ursolic acid and its isomer oleanolic acid are responsible for the anti-dementia effects of Ocimum sanctum.Feb 25, 2022

Ursolic Acid and oleanolic acid reduced the proliferation of A549 cells in nude mice.Dec 31, 2015

Ursolic acid and rosmarinic acid ameliorate alterations in hippocampal neurogenesis and social memory induced by amyloid beta.Dec 31, 2021

Ursolic acid and tomatidine increased muscle mass and also increased musle strength in aged animals. Sep 02, 2015

Ursolic acid attenuated renal tubulointerstitial fibrosis by inhibiting epithelial-mesenchymal transition.Nov 30, 2019

Ursolic acid attenuates atherosclerosis in mice.May 06, 2018

Ursolic acid attenuates cigarette smoke induced rat emphysema.May 31, 2017

Ursolic acid can alleviate the memory impairments induced by Aβ25-35 in mice.May 31, 2016

Ursolic acid can be a good anti-cancer agent for targeted therapy or combination therapy with DNA damaging drugs for lung cancer patients.Dec 31, 2014

Ursolic acid can be the protective treatment for treatment of gestational diabetes mellitus. Feb 14, 2021

Ursolic acid can be used as a potential chemopreventive and therapeutic agent for gastric cancer.Sep 22, 2019

Ursolic acid can effectively inhibit the proliferation and migration and induce apoptosis of gastric cancer cells.Dec 31, 2018

Ursolic acid could attenuate cerebral ischemia and reperfusion injury.Dec 31, 2015

Ursolic acid could protect against liver damage from high intake of choline. Aug 23, 2016

Ursolic acid demonstrated its potential therapeutic utility to improve IR, hyperinsulinemia, and inflammation observed in obesity and diabetes.Nov 19, 2019

Ursolic acid derivatives as potential antidiabetic agents.Jan 28, 2018

Ursolic acid effectively ameliorated high fat diet induced hepatic steatosis.Dec 31, 2013

Ursolic acid enhances autophagic clearance and ameliorates motor and non-motor symptoms in Parkinson's disease model.Sep 21, 2022

Ursolic acid enhances myelin repair in adult mice brains.Aug 16, 2022

Ursolic acid enhances stress resistance, reduces ROS accumulation and prolongs life span in C. elegans serotonin-deficient mutants.Feb 16, 2021

Ursolic acid exhibits significant anti-tumor effects by suppressing cell proliferation, promoting apoptosis in gallbladder cancer cells. Dec 31, 2013

Ursolic acid from Trailliaedoxa gracilis induces apoptosis in medullary thyroid carcinoma cells.Jul 06, 2015

Ursolic acid has a obvious protective effect on myocardial injury in mice with diabetes induced by high-fat diet.Apr 07, 2018

Ursolic acid has an anti-fibrotic effect and attenuates the mitochondrial and lysosomal dysfunction in Isoproterenol-induced myocardial infarction.Apr 11, 2019

Ursolic acid improves diabetic nephropathy via suppression of oxidative stress and inflammation.Aug 31, 2018

Ursolic acid improves intestinal damage and bacterial dysbiosis in liver fibrosis mice.Dec 31, 2018

Ursolic acid induced neural regeneration after sciatic nerve injury in mice. Sep 24, 2013

Ursolic acid inhibits colorectal cancer angiogenesis through suppression of multiple signaling pathways.Oct 31, 2013

Ursolic acid inhibits the cholesterol biosynthesis and alleviates high fat diet-induced hypercholesterolemia.Jul 31, 2022

Ursolic acid inhibits the development of nonalcoholic fatty liver disease by attenuating endoplasmic reticulum stress.Apr 30, 2015

Ursolic acid inhibits the progression of arteriosclerosis and restenosis after angioplasty. Jan 01, 2006

Ursolic acid may ameliorate the deleterious effects of diet-induced obesity and associated complications such as hepatic fibrosis.Nov 08, 2018

Ursolic acid may be a new chemotherapeutic candidate against prostate cancer. Dec 31, 2014

Ursolic acid may be a potential drug for reducing ischemia/reperfusion induced acute kidney injury.Aug 18, 2016

Ursolic Acid

View the Evidence:
208 Abstracts with Ursolic Acid Research