Valerian

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52 Diseases Researched for Valerian
NameACCKFocus
Insomnia1066Locked
Sleep Disorders440Locked
Anxiety432Locked
Cognitive Decline/Dysfunction220Locked
Dysmenorrhea220Locked
Hot Flash220Locked
Stress220Locked
Anxiety Disorders518Locked
Premenstrual syndrome211Locked
Attention Deficit Hyperactivity Disorder110Locked
Benzodiazepine Dependence/Withdrawal110Locked
Cardiac Surgery110Locked
Coronary Bypass Surgery110Locked
Dental Care110Locked
HIV Drug-Induced Toxicity 110Locked
Menopausal Syndrome110Locked
Menstrual Cramps110Locked
Obsessive-Compulsive Disorder110Locked
Postmenopausal Disorders110Locked
Postmenopausal Disorders: Insomnia110Locked
Restless Legs Syndrome110Locked
Tooth Extraction: Wisdom110Locked
Uterine Cramps110Locked
Depression35Locked
Lipid Peroxidation24Locked
Muscle Atrophy 13Locked
Aging12Locked
Alzheimer's Disease12Locked
Anxiety: Generalized12Locked
Brain: Microglial Activation12Locked
Bronchospasm: Acute12Locked
Cerebral Ischemia12Locked
Chronic Pain12Locked
Colitis12Locked
Convulsions12Locked
Convulsive Seizures12Locked
Coronary Artery Spasm 12Locked
Gastric Ulcer12Locked
Generalized Anxiety Disorder12Locked
Glioblastoma12Locked
Liver Cancer12Locked
Morphine Tolerance/Dependence12Locked
Muscle Spasm12Locked
Muscle Spasticity12Locked
Myocardial Ischemia12Locked
Neuropathic Pain12Locked
Oxidative Stress12Locked
Seizures: Drug-Induced12Locked
Ulcerative Colitis12Locked
Cancers: All11Locked
HIV Infections11Locked
Multiple Sclerosis11Locked
27 Pharmacological Actions Researched for Valerian
NameACCKFocus
Neuroprotective Agents838Locked
Anti-Anxiety Agents424Locked
Antispasmodic424Locked
Anxiolytic314Locked
GABA Modulators212Locked
Sedative effects110Locked
Antioxidants49Locked
Antidepressive Agents35Locked
Antiproliferative 35Locked
Analgesics24Locked
Anticonvulsants24Locked
Apoptotic24Locked
Acetylcholinesterase Inhibitor12Locked
Anti-Ulcer Agents12Locked
Anti-metastatic12Locked
Bronchoconstrictor Agents12Locked
Cardioprotective12Locked
Catalase Up-Regulation12Locked
Chemopreventive12Locked
Gastrointestinal Agents12Locked
Gastroprotective12Locked
Hypotensive12Locked
Monoaminergic 12Locked
Superoxide Dismutase Up-regulation12Locked
Anti-Inflammatory Agents11Locked
Brain-derived neurotrophic factor modulator11Locked
Reverse Transcriptase Inhibitors11Locked

View the Evidence:
58 Abstracts with Valerian Research

[+]

" Valerian seems to be an effective treatment for dysmenorrhea, probably because of its antispasmodic effects."Sep 27, 2011

Pubmed Data : Int J Gynaecol Obstet. 2011 Sep 27. Epub 2011 Sep 27. PMID: 21959068
Article Published Date : Sep 27, 2011
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Dysmenorrhea, Menstrual Cramps
Pharmacological Actions : Antispasmodic
[+]

A combination of valerian and hops reduces sleep latency in patients suffering from non-organic insomnia. Sep 01, 2007

Pubmed Data : Phytother Res. 2007 Sep;21(9):847-51. PMID: 17486686
Article Published Date : Sep 01, 2007
Study Type : Human Study
Additional Links
Substances : Hops, Valerian
Diseases : Insomnia
[+]

Assessment of valerian for conscious sedation of patients during the extraction of impacted mandibular third molars.Aug 31, 2019

Pubmed Data : J Oral Maxillofac Surg. 2019 Sep ;77(9):1796.e1-1796.e8. Epub 2019 May 9. PMID: 31158346
Article Published Date : Aug 31, 2019
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Dental Care, Tooth Extraction: Wisdom
Pharmacological Actions : Sedative effects
Additional Keywords : Plant Extracts
[+]

Combined treatment with valerian and lemon balm provides a viable option in addition to counselling and education.Jun 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytomedicine. 2014 Jul-Aug;21(8-9):1098-103. Epub 2014 May 15. PMID: 24837472
Article Published Date : Jun 30, 2014
Study Type : Human Study
Additional Links
Substances : Lemon Balm, Valerian
Diseases : Attention Deficit Hyperactivity Disorder
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Effects of valerian on subjective sedation, field sobriety testing and driving simulator performance.Jun 30, 2016

Pubmed Data : Accid Anal Prev. 2016 Jul ;92:240-4. Epub 2016 Apr 22. PMID: 27110643
Article Published Date : Jun 30, 2016
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Insomnia
Additional Keywords : Phytotherapy
[+]

Fennel-valerian extract was effective for relieving sleep disorders as well as the severity and frequency of hot flashes.Mar 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Menopausal Med. 2023 Apr ;29(1):21-28. PMID: 37160299
Article Published Date : Mar 31, 2023
Study Type : Human Study
Additional Links
Substances : Fennel, Valerian
Diseases : Hot Flash, Sleep Disorders
[+]

findings indicate that valerian root extract alters functional brain connectivity in relation to anxiety.Jan 09, 2019

Pubmed Data : Phytother Res. 2019 Jan 10. Epub 2019 Jan 10. PMID: 30632220
Article Published Date : Jan 09, 2019
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Anxiety
Pharmacological Actions : Anti-Anxiety Agents
Additional Keywords : Plant Extracts
[+]

Health-care providers should consider Valerian to be effective for menopausal women with hot flashes.Dec 31, 2017

Pubmed Data : Women Health. 2018 03 ;58(3):297-304. Epub 2017 Mar 17. PMID: 28278010
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Hot Flash, Menopausal Syndrome
[+]

In a study of 918 children, valerian and lemon balm reduced dyssomnia and restlessness symptoms from moderate/severe to mild or absent in most patients. Jun 01, 2006

Pubmed Data : Phytomedicine. 2006 Jun ;13(6):383-7. Epub 2006 Feb 17. PMID: 16487692
Article Published Date : Jun 01, 2006
Study Type : Human Study
Additional Links
Substances : Lemon Balm, Valerian
Diseases : Sleep Disorders
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Kava and valerian root are effective in the treatment of stress-induced insomnia. Sep 01, 2001

Pubmed Data : Phytother Res. 2001 Sep;15(6):549-51. PMID: 11536390
Article Published Date : Sep 01, 2001
Study Type : Human Study
Additional Links
Substances : Kava Kava, Valerian
Diseases : Insomnia, Stress
[+]

Melissa officinalis and Valeriana officinalis have an anti-anxiety effect during laboratory-induced stress. Feb 01, 2006

Pubmed Data : Phytother Res. 2006 Feb;20(2):96-102. PMID: 16444660
Article Published Date : Feb 01, 2006
Study Type : Human Study
Additional Links
Substances : Melissa (Lemonbalm), Valerian
Diseases : Anxiety Disorders, Stress
Pharmacological Actions : Anxiolytic
Additional Keywords : Plant Extracts
[+]

The consumption of oral valerian root extract over 30 nights could significantly improve the patients' sleep quality safely after CABG surgery.Dec 31, 2020

Pubmed Data : Chin J Integr Med. 2021 Jan ;27(1):7-15. Epub 2021 Jan 8. PMID: 33420602
Article Published Date : Dec 31, 2020
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Cardiac Surgery, Sleep Disorders
Additional Keywords : Phytotherapy, Plant Extracts
[+]

The findings of this study indicated that valerian could be effective and significantly improve patients' cognitive status.Dec 26, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Nephrol. 2018 Dec 27 ;19(1):379. Epub 2018 Dec 27. PMID: 30591031
Article Published Date : Dec 26, 2018
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

These results suggest that Valeriana Officinalis L. has some anti-obsessive and compulsive effects.Oct 10, 2011

Pubmed Data : J Complement Integr Med. 2011 Oct 11 ;8. Epub 2011 Oct 11. PMID: 22718671
Article Published Date : Oct 10, 2011
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Obsessive-Compulsive Disorder
Pharmacological Actions : GABA Modulators
Additional Keywords : Plant Extracts
[+]

V. officinalis root extract may prevent early postoperative cognitive dysfunction after on-pump coronary artery bypass graft surgery.Feb 28, 2015

Pubmed Data : Psychopharmacology (Berl). 2015 Mar ;232(5):843-50. Epub 2014 Aug 31. PMID: 25173770
Article Published Date : Feb 28, 2015
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Cognitive Decline/Dysfunction, Coronary Bypass Surgery
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Valerian and lemon balm may assist in reducing symptoms of sleep disorder during the menopause.Oct 31, 2013

Pubmed Data : Complement Ther Clin Pract. 2013 Nov ;19(4):193-6. Epub 2013 Sep 10. PMID: 24199972
Article Published Date : Oct 31, 2013
Study Type : Human Study
Additional Links
Substances : Melissa (Lemonbalm), Valerian
Diseases : Postmenopausal Disorders: Insomnia, Sleep Disorders
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Valerian attenuates the insomnia associated with benzodiazepine withdrawal. Apr 01, 2002

Pubmed Data : : Prog Neuropsychopharmacol Biol Psychiatry. 2002 Apr;26(3):539-45. PMID: 11999905
Article Published Date : Apr 01, 2002
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Benzodiazepine Dependence/Withdrawal
[+]

Valerian extract inhibits contractility of the human uterus justifying its traditional use in the treatment of uterine cramping associated with dysmenorrhoea. Feb 01, 2009

Pubmed Data : J Pharm Pharmacol. 2009 Feb;61(2):251-6. PMID: 19178774
Article Published Date : Feb 01, 2009
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Dysmenorrhea, Uterine Cramps
Pharmacological Actions : Antispasmodic
[+]

Valerian extract is comparable to the drug oxazepam in the treatment of non-organic insomnia. Nov 25, 2002

Pubmed Data : Eur J Med Res. 2002 Nov 25;7(11):480-6. PMID: 12568976
Article Published Date : Nov 25, 2002
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Insomnia
Additional Keywords : Natural Substances Versus Drugs
[+]

Valerian improves sleep quality in postmenopausal women. Jul 14, 2011

Pubmed Data : Menopause. 2011 Jul 14. Epub 2011 Jul 14. PMID: 21775910
Article Published Date : Jul 14, 2011
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Insomnia, Postmenopausal Disorders
[+]

Valerian improves symptoms of restless leg syndrome. Mar 01, 2009

Pubmed Data : Altern Ther Health Med. 2009 Mar-Apr;15(2):22-8. PMID: 19284179
Article Published Date : Mar 01, 2009
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Restless Legs Syndrome
[+]

Valerian may be considered as a potential option in preventing neuropsychiatric adverse effects of efavirenz in HIV-positive patients.May 31, 2017

Pubmed Data : Ann Pharmacother. 2017 Jun ;51(6):457-464. Epub 2017 Feb 1. PMID: 28478716
Article Published Date : May 31, 2017
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Anxiety, HIV Drug-Induced Toxicity
Pharmacological Actions : Neuroprotective Agents
[+]

Valerian root extract may reduce emotional, physical, and behavioral symptoms of premenstrual syndrome.Jun 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Complement Med. 2016 Jul ;6(3):309-15. Epub 2016 Jan 19. PMID: 27419099
Article Published Date : Jun 30, 2016
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Premenstrual syndrome
[+]

Valerian significantly improves sleep in a randomized human trial. Apr 01, 1989

Pubmed Data : Pharmacol Biochem Behav. 1989 Apr;32(4):1065-6. PMID: 2678162
Article Published Date : Apr 01, 1989
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Insomnia
[+]

Valeriana officinalis root extract modulates cortical excitatory circuits in humans.Dec 31, 2016

Pubmed Data : Neuropsychobiology. 2017 ;75(1):46-51. Epub 2017 Oct 17. PMID: 29035887
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Anxiety
Pharmacological Actions : Anti-Anxiety Agents
Additional Keywords : Plant Extracts
[+]

Antioxidant activity of Valeriana fauriei protects against dexamethasone-induced muscle atrophy.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2022 ;2022:3645431. Epub 2022 Jan 12. PMID: 35069972
Article Published Date : Dec 31, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Valerian
Diseases : Muscle Atrophy
Pharmacological Actions : Antioxidants
Problem Substances : Dexamethasone
[+]

"Valeriana wallichii root extract improves sleep quality and modulates brain monoamine level in rats."Jul 14, 2012

Pubmed Data : Phytomedicine. 2012 Jul 15 ;19(10):924-9. Epub 2012 Jul 4. PMID: 22766307
Article Published Date : Jul 14, 2012
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Insomnia
Pharmacological Actions : Monoaminergic
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Anxiolytic properties of Valeriana officinalis in the zebrafish: a possible role for metabotropic glutamate receptors.Oct 31, 2012

Pubmed Data : Planta Med. 2012 Nov ;78(16):1719-24. Epub 2012 Aug 24. PMID: 22923195
Article Published Date : Oct 31, 2012
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Anxiety
Pharmacological Actions : Anti-Anxiety Agents
Additional Keywords : Phytotherapy
[+]

Protective effect of valerian extract capsule (VEC) on ethanol- and indomethacin-induced gastric mucosa injury.Nov 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2022 Dec ;60(1):1095-1105. PMID: 35658820
Article Published Date : Nov 30, 2022
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Gastroprotective
Additional Keywords : Drug: Indomethacin, Plant Extracts
Problem Substances : Indomethacin
[+]

Sesquiterpenes and a monoterpenoid with acetylcholinesterase inhibitory activity from Valeriana officinalis.Mar 31, 2016

Pubmed Data : Fitoterapia. 2016 Apr ;110:142-9. Epub 2016 Mar 11. PMID: 26976216
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
[+]

Simultaneous use of valerian root and turnip extracts is recommended for analgesic effects in both acute and chronic phases of the pain.Aug 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Plast Surg. 2018 Sep ;7(3):345-350. PMID: 30560075
Article Published Date : Aug 31, 2018
Study Type : Animal Study
Additional Links
Substances : Mustard: Field/Turnip, Valerian
Diseases : Chronic Pain
Pharmacological Actions : Analgesics
Additional Keywords : Plant Extracts
[+]

The anxiolytic effects of a Valerian extract is based on valerenic acid.Jul 27, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2014 Jul 28 ;14:267. Epub 2014 Jul 28. PMID: 25066015
Article Published Date : Jul 27, 2014
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Anxiety Disorders
Pharmacological Actions : Anti-Anxiety Agents
Additional Keywords : Plant Extracts
[+]

The results of the present study showed that the hydro-alcoholic extract of V. officinalis prevents depression like behaviour in ovalbumin sensitized rats.Mar 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharm Bioallied Sci. 2014 Apr ;6(2):97-103. PMID: 24741277
Article Published Date : Mar 31, 2014
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]

Therapeutic effects of Valeriana jatamansi on ulcerative colitis.Aug 03, 2023

Pubmed Data : J Proteome Res. 2023 Aug 4 ;22(8):2669-2682. Epub 2023 Jul 21. PMID: 37475705
Article Published Date : Aug 03, 2023
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Colitis, Ulcerative Colitis
Pharmacological Actions : Gastrointestinal Agents
[+]

These results indicate that valerian exhibits inhibitory effects on rat hepatocarcinogenesis.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(11):e113610. Epub 2014 Nov 24. PMID: 25419570
Article Published Date : Dec 31, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Valerian
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Chemopreventive
Additional Keywords : Plant Extracts
[+]

V. officinalis extract may have a protective effect against myocardial ischemia-reperfusion.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Endocrinol (Buchar). 2023 ;19(2):178-186. Epub 2023 Oct 27. PMID: 37908890
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Myocardial Ischemia
Pharmacological Actions : Antioxidants, Cardioprotective
[+]

V. officinalis extract was effective in reducing the toxicity induced by rotenone in D. melanogaster.Jun 30, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neurotoxicology. 2013 Jul ;37:118-26. Epub 2013 Apr 29. PMID: 23639798
Article Published Date : Jun 30, 2013
Study Type : Insect Study
Additional Links
Substances : Valerian
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Superoxide Dismutase Up-regulation
Additional Keywords : Phytotherapy, Plant Extracts
Problem Substances : Rotenone
[+]

Valerenic acid and valerian extracts have anticonvulsant properties in adult zebrafish. Jul 13, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2015 Jul 14 ;15:228. Epub 2015 Jul 14. PMID: 26168917
Article Published Date : Jul 13, 2015
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Seizures: Drug-Induced
Pharmacological Actions : Anticonvulsants
Additional Keywords : Natural Substance/Drug Synergy, Plant Extracts
[+]

Valerian contains compounds with antispasmodic effects on stimulated smooth muscle cells without activating the autonomic nervous system. Jun 18, 2008

Pubmed Data : Cancer Lett. 2008 Jun 18;264(2):218-28. Epub 2008 Mar 7. PMID: 7114974
Article Published Date : Jun 18, 2008
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Muscle Spasm, Muscle Spasticity
Pharmacological Actions : Antispasmodic
[+]

Valerian essential oil for treating insomnia via the serotonergic synapse pathway.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2022 ;9:927434. Epub 2022 Jul 28. PMID: 35990355
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Insomnia
Additional Keywords : Essential Oils
[+]

Valerian extract has anxiety-reducing and anti-depressant effects, but is not a sedative and does not interfere with muscle function. Jan 01, 2008

Pubmed Data : Phytomedicine. 2008 Jan;15(1-2):2-15. PMID: 18160026
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Anxiety Disorders, Depression
Pharmacological Actions : Antidepressive Agents
Additional Keywords : Drug-Plant-Vitamin Synergies, Plant Extracts
[+]

Valerian has anticonvulsive properties. Feb 03, 2010

Pubmed Data : J Ethnopharmacol. 2010 Feb 3;127(2):313-8. Epub 2009 Nov 10. PMID: 19900527
Article Published Date : Feb 03, 2010
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Convulsions, Convulsive Seizures
Pharmacological Actions : Anticonvulsants
[+]

Valerian root appears to reduce the symptoms of morphine withdrawal syndrome. Jun 01, 2006

Pubmed Data : Addict Biol. 2006 Jun;11(2):145-51. PMID: 16800827
Article Published Date : Jun 01, 2006
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Morphine Tolerance/Dependence
[+]

Valerian root extract and valerenic acid enhance cognitive function, promote cell proliferation and neuroblast differentiation.Oct 31, 2013

Pubmed Data : Exp Gerontol. 2013 Nov ;48(11):1369-77. Epub 2013 Sep 18. PMID: 24055511
Article Published Date : Oct 31, 2013
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Aging, Lipid Peroxidation
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Valerian root extracts has protective effects against ischemic injury in the hippocampal pyramidal neurons.May 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Med Food. 2015 Jun ;18(6):642-7. Epub 2015 Mar 18. PMID: 25785762
Article Published Date : May 31, 2015
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Brain: Microglial Activation, Cerebral Ischemia, Lipid Peroxidation
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Valerian root has antibronchospastic, antihypertensive and anticoronaryspastic properties. Jun 13, 2007

Pubmed Data : J Ethnopharmacol. 2007 Jun 13;112(2):361-7. Epub 2007 Mar 20. PMID: 17467210
Article Published Date : Jun 13, 2007
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Bronchospasm: Acute, Coronary Artery Spasm
Pharmacological Actions : Antispasmodic, Bronchoconstrictor Agents, Hypotensive
Additional Keywords : Drug: Nifedipine, Natural Substances Versus Drugs
[+]

Valerian treatment could repair the allodynia induced by neuropathy.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sleep Sci. 2021 ;14(Spec 2):133-139. PMID: 35082982
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Neuropathic Pain
Pharmacological Actions : Analgesics
[+]

Valerian's anti-anxiety action is due to its action on GABA receptors.Jun 17, 2008

Pubmed Data : Neuropharmacology. 2008 Jun 17. PMID: 18602406
Article Published Date : Jun 17, 2008
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Anxiety: Generalized, Anxiety Disorders, Generalized Anxiety Disorder
Pharmacological Actions : Anxiolytic, GABA Modulators
[+]

Valeriana officinalis root extracts have potent anxiolytic effects in rats.Dec 28, 2009

Pubmed Data : Phytomedicine. 2009 Dec 28. Epub 2009 Dec 28. PMID: 20042323
Article Published Date : Dec 28, 2009
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Anxiety Disorders
Pharmacological Actions : Anxiolytic
[+]

Valtrate elicits anti-glioblastoma activity through inhibition of the PDGFRA/MEK/ERK signaling pathway.Feb 23, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Transl Med. 2023 Feb 24 ;21(1):147. Epub 2023 Feb 24. PMID: 36829235
Article Published Date : Feb 23, 2023
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Glioblastoma
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
[+]

A meta-analysis of 16 studies indicates that Valerian root might improve sleep quality without producing side effects. Dec 01, 2006

Pubmed Data : Am J Med. 2006 Dec;119(12):1005-12. PMID: 17145239
Article Published Date : Dec 01, 2006
Study Type : Review
Additional Links
Substances : Valerian
Diseases : Insomnia
[+]

A review of herbal therapy in multiple sclerosis.Oct 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Pharm Bull. 2018 Nov ;8(4):575-590. Epub 2018 Nov 29. PMID: 30607330
Article Published Date : Oct 31, 2018
Study Type : Review
Additional Links
Substances : Cannabis, Cranberry, Frankincense, Ginger, Ginkgo biloba, Ginseng, Grape, Kava Kava, Nigella sativa (aka Black Seed), Saffron, St. Johns Wort, Turmeric, Valerian
Diseases : Multiple Sclerosis
[+]

Chemical structures and anti-proliferative effects of Valeriana fauriei constituents on cancer stem cells.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chem Pharm Bull (Tokyo). 2023 ;71(7):495-501. PMID: 37394597
Article Published Date : Dec 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Valerian
Diseases : Cancers: All
Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative
Additional Keywords : Cancer Stem Cells
[+]

Cytoprotective effect of Valeriana officinalis extract on an in vitro experimental model of Parkinson disease.Jan 31, 2009

Pubmed Data : Neurochem Res. 2009 Feb ;34(2):215-20. Epub 2008 May 30. PMID: 18512151
Article Published Date : Jan 31, 2009
Study Type : In Vitro Study
Additional Links
Substances : Valerian
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

The roles of valerenic acid on BDNF expression in the SH-SY5Y cell.Oct 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi Pharm J. 2018 Nov ;26(7):960-964. Epub 2018 Jun 8. PMID: 30416353
Article Published Date : Oct 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Valerian
Diseases : Depression
Pharmacological Actions : Antidepressive Agents, Brain-derived neurotrophic factor modulator
[+]

This research demonstrated efficacy and safety of Iranian herbal medicines in alleviating PMS.Feb 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2018 Mar-Apr;8(2):96-113. PMID: 29632841
Article Published Date : Feb 28, 2018
Study Type : Review
Additional Links
Substances : Chamomile, Chaste Tree (Chasteberry), Curcumin, Fennel, Flaxseed, Ginger, Lemon Balm, Orange, Saffron, St. Johns Wort, Valerian, Wheat Germ, Zataria multiflora
Diseases : Premenstrual syndrome
Additional Keywords : Traditional Iranian Medicine
[+]

Valerian root contains the compound valtrate with has anti-HIV activity. Oct 21, 2002

Pubmed Data : Bioorg Med Chem Lett. 2002 Oct 21;12(20):2807-10. PMID: 12270151
Article Published Date : Oct 21, 2002
Study Type : In Vitro Study
Additional Links
Substances : Valerian
Diseases : HIV Infections
Pharmacological Actions : Reverse Transcriptase Inhibitors
[+]

Valerian root may be beneficial in reducing insomnia associated with oxidative stress. Aug 01, 2009

Pubmed Data : Neurochem Res. 2009 Aug;34(8):1372-9. Epub 2009 Feb 4. PMID: 19191025
Article Published Date : Aug 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Valerian
Diseases : Insomnia
Pharmacological Actions : Neuroprotective Agents

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