Vitamin E: Gamma-tocotrienol

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31 Diseases Researched for Vitamin E: Gamma-tocotrienol

Name	AC	CK
Thrombosis	1	10
Chemotherapy and Radiation Toxicity	2	4
Radiation Induced Illness	2	4
Colon Cancer	3	3
Atherosclerosis	1	2
Breast Cancer	2	2
Cancers: All	2	2
Cardiovascular Diseases	1	2
Coronary Artery Disease	1	2
Melanoma	2	2
Osteopenia	1	2
Osteoporosis	1	2
Oxidative Stress	1	2
Pancytopenia	1	2
Radiation Associated Toxicity: Cobalt-60	1	2
Breast Cancer: Drug Resistant	1	1
Breast Cancer: HER-2 Overexpressed	1	1
Cancers: Drug Resistant	1	1
Cervical Cancer	1	1
Colon Cancer: Prevention	1	1
Colorectal Cancer	1	1
Diabetes Mellitus: Type 2	1	1
Gastric Cancer	1	1
Glioblastoma	1	1
Lipopolysaccharide-Induced Toxicity	1	1
Liver Cancer	1	1
Malignant Melanoma	1	1
Melanoma: Metastatic	1	1
Neuroblastoma	1	1
Obesity	1	1
Oral Cancer	1	1

31 Pharmacological Actions Researched for Vitamin E: Gamma-tocotrienol

Name	AC	CK
Radioprotective	6	11
Apoptotic	10	10
Antiproliferative	6	6
Antioxidants	4	5
Cell cycle arrest	5	5
Chemosensitizer	5	5
Anti-Inflammatory Agents	4	4
NF-kappaB Inhibitor	3	3
Anti-atherogenic	1	2
Antineoplastic Agents	2	2
Cardioprotective	1	2
Chemoprotective Agents	2	2
Matrix Metalloproteinase-12 (MMP-12) Inhibitor	1	2
Matrix metalloproteinase-9 (MMP-9) inhibitor	1	2
MicroRNA modulator	1	2
Anti-Angiogenic	1	1
Anticarcinogenic Agents	1	1
Autophagy Up-regulation	1	1
Bcl-2 protein down-regulation	1	1
Caspase-3 Activation	1	1
Chemotherapeutic	1	1
Immunomodulatory	1	1
Interleukin-1 beta downregulation	1	1
Interleukin-18 down-regulation	1	1
Interleukin-6 Downregulation	1	1
Multidrug Resistance Gene Modulators	1	1
Nrf2 activation	1	1
Paraptosis	1	1
Tumor Necrosis Factor (TNF) Alpha Inhibitor	1	1
Tumor Suppressor Protein p53 Upregulation	1	1
Wnt/β-catenin pathway down-regulation	1	1

Research Articles 28
Cumulative Knowledge Score 45
Overall Research Rating GOOD

View the Evidence:
33 Abstracts with Vitamin E: Gamma-tocotrienol Research

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View the Evidence: 33 Abstracts with Vitamin E: Gamma-tocotrienol Research

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Vitamin E as Gamma-Tocopherol decreases LDL cholesterol, platelet aggregation and mean platelet account, indicating its value in decreasing the risk of thrombotic events. Jan 01, 2007

Gamma-Tocotrienol ameliorates intestinal radiation injury and reduces vascular oxidative stress after total-body irradiation.May 01, 2009

Gamma-tocotrienol could be used as an intestinal radioprotector.Mar 05, 2019

Gamma-tocotrienol could be used in prevention of radiation-induced damage to the spleen.Apr 30, 2016

Gamma-tocotrienol is a potent radioprotective agent. Jul 01, 2009

Gamma-tocotrienol is a promising radiation countermeasure.Dec 31, 2015

Gamma-tocotrienol supplementation is effective in attenuating NAFLD and fibrosis.Jan 10, 2018

This study demonstrate the potential of gamma-tocotrienol as a promising radioprotector.Feb 29, 2016

Vitamin E has a potential role as an atheroprotective agent in early and established atherosclerosis.Dec 31, 2015

Vitamin E, with gamma-tocotrienol, can promote bone formation in normal rats. Feb 10, 2010

γ-tocotrienol potentiates and sustains the 5-FU-induced expression of Nrf2 in human keratinocytes, leading to the continuous degradation of 5-FU-generated ROSMar 31, 2015

Co-treatment with gamma-tocotrienol and baicalein enhanced the anti-proliferative activity of baicalein.May 12, 2016

Combined use of lower concentrations of jerantinine A and γ-tocotrienol induced potent cytotoxic effects on U87MG cancer cells.Jun 30, 2017

Dietary γT3-enriched food would be a simple strategy to attenuate adiposity and to lessen obesity-mediated metabolic dysfunction.Dec 31, 2015

Gamma tocotrienol has a chemosensitizing property.Oct 22, 2010

Gamma tocotrienol inhibited the growth of human colorectal cancer cells and sensitised them to capecitabine.Aug 29, 2016

Gamma tocotrienol works synergistically with statins to inhibit mammary tumor cell progression.Jun 01, 2009

Gamma-tocotrienol acts as a BH3 mimetic to induce apoptosis in neuroblastoma SH-SY5Y cells.Feb 08, 2016

Gamma-tocotrienol enhances the chemosensitivity of human oral cancer cells to docetaxel.Dec 31, 2012

Gamma-tocotrienol has broad therapeutic activity against human melanoma cells. Jan 01, 2009

Gamma-tocotrienol induces apoptosis in prostate cancer cells.Mar 06, 2019

Gamma-tocotrienol induces programmed cell death in human gastric cancer cells. Jun 01, 2008

Gamma-tocotrienol induces programmed cell death in human hepatoma cells.Oct 01, 2006

Gamma-tocotrienol inhibits proliferation and induces apoptosis in human cervical cancer cells.Aug 03, 2017

Gamma-tocotrienol inhibits proliferation and induces programmed cell death in human colon cancer cells. Jul 01, 1995

Gamma-tocotrienol inhibits the NLRP3 inflammasome thereby delaying the progression of type 2 diabetes.Dec 31, 2015

Gamma-tocotrienol is a promising natural drug for future breast cancer therapy.Dec 31, 2014

Gamma-tocotrienol profoundly alters sphingolipids in cancer cells.Apr 11, 2017

Gamma-tocotrienol reverses multidrug resistance of breast cancer cells.Nov 14, 2016

Gamma-Tocotrienol-induced disruption of lipid rafts in human breast cancer cells is associated with a reduction in exosome heregulin content.Sep 30, 2017

Tocotrienols inhibit lipopolysaccharide-induced pro-inflammatory cytokines in macrophages of female mice.Jan 01, 2010

γ-tocotrienol induced upregulation of A20 zinc finger protein.May 21, 2015

γ-Tocotrienol inhibited cell proliferation and induced a paraptosis-like cell death in human colon cancer cell and may be a potential treatment to prevent and treat apoptosis-resistance colon cancer.Dec 31, 2012

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Vitamin E: Gamma-tocotrienol

View the Evidence:
33 Abstracts with Vitamin E: Gamma-tocotrienol Research