Vitamin K2

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83 Diseases Researched for Vitamin K2
NameACCKFocus
Osteoporosis28202Locked
Bone Fractures985Locked
Coronary Artery Disease451Locked
Liver Cancer634Locked
Arterial Hardening: Elasticity330Locked
Cardiac Mortality 230Locked
Postmenopausal Disorders230Locked
Diabetes Mellitus: Type 2625Locked
Cardiovascular Diseases423Locked
Aortic Calcification222Locked
Vitamin K Deficiency322Locked
Arteriosclerosis120Locked
C-Reactive Protein220Locked
Liver Cirrhosis120Locked
Mortality: All-Cause120Locked
Myocardial Infarction120Locked
Obesity220Locked
Organ Transplantation120Locked
Organ Transplantation: Heart120Locked
Organ Transplantation: Lung120Locked
Prostate Cancer: Prevention120Locked
Rheumatoid Arthritis220Locked
Arterial Calcification414Locked
Atherosclerosis314Locked
Cancers: All312Locked
Depression212Locked
Osteopenia212Locked
Acute lymphoblastic leukemia (ALL)110Locked
All-Cause Mortality110Locked
Anemia: Aplastic110Locked
Athletic Performance110Locked
Cancer Mortality110Locked
Carotid Stenosis110Locked
Cerebral Palsy110Locked
Chemotherapy110Locked
Coronavirus Disease (Covid-19)110Locked
Corticosteroid-Induced Toxicity110Locked
Hip Fracture110Locked
Insulin Resistance110Locked
Menopausal Syndrome110Locked
Multiple Sclerosis110Locked
Myelodysplastic Syndrome110Locked
Osteoporosis: Steroid-Induced110Locked
Polycystic Ovary Syndrome110Locked
Thrombocytopenia110Locked
Osteonecrosis26Locked
Atopic Dermatitis15Locked
Aging24Locked
Breast Cancer: Triple Negative 44Locked
Diabetic Complications24Locked
Prostate Cancer23Locked
Aluminum Toxicity 12Locked
Alzheimer's Disease12Locked
Anxiety12Locked
Breast Cancer22Locked
Chronic Kidney Disease (CKD)12Locked
Cognitive Decline/Dysfunction12Locked
Colitis12Locked
Colon Cancer12Locked
Dysbiosis12Locked
Dyslipidemias12Locked
Endothelial Dysfunction12Locked
High Fat Diet12Locked
Lipopolysaccharide-Induced Toxicity12Locked
Lung Damage12Locked
Lymphoma12Locked
Metabolic Syndrome X12Locked
Nonalcoholic fatty liver disease (NAFLD)12Locked
Ulcerative Colitis12Locked
Acute Myeloid Leukemia11Locked
Arthritis11Locked
Bladder Cancer11Locked
Cancers: Radiation-Resistant11Locked
Coronavirus Infection11Locked
Diabetes: Bone Quality & Density11Locked
Hypercalcemia11Locked
Hypoxia11Locked
Inflammation11Locked
Mitochondrial Diseases11Locked
Mitochondrial Dysfunction 11Locked
Neurodegenerative Diseases11Locked
Osteoarthritis11Locked
Parkinson's Disease11Locked
42 Pharmacological Actions Researched for Vitamin K2
NameACCKFocus
Osteoprotective 864Locked
Cardioprotective340Locked
Anti-Inflammatory Agents627Locked
Anticarcinogenic Agents222Locked
Antidepressive Agents322Locked
Hepatoprotective222Locked
Matrix metalloproteinase-3 (MMP-3) inhibitor220Locked
Antiproliferative 716Locked
Anti-atherogenic314Locked
Anti-Anxiety Agents212Locked
Anticholesteremic Agents110Locked
Chemoprotective Agents110Locked
Gastrointestinal Agents110Locked
Hypolipidemic110Locked
Insulin Sensitizers110Locked
Apoptotic56Locked
NF-kappaB Inhibitor46Locked
Anti-Apoptotic35Locked
Immunosuppressive Agents15Locked
MicroRNA modulator15Locked
Neuroprotective Agents35Locked
Osteogenic15Locked
Chemopreventive24Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor24Locked
Antineoplastic Agents33Locked
Angiogenesis Inhibitors12Locked
Anti-Bacterial Agents12Locked
Anti-metastatic12Locked
Antioxidants12Locked
Brain-derived neurotrophic factor modulator12Locked
Cell cycle arrest22Locked
Hypoglycemic Agents12Locked
Interleukin-1 beta downregulation12Locked
Interleukin-10 upregulation12Locked
Interleukin-6 Downregulation12Locked
Renoprotective12Locked
Chemosensitizer11Locked
Chemotherapeutic11Locked
Chondroprotective11Locked
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor11Locked
Immunomodulatory11Locked
Radiosensitizer11Locked
Related Topics

The Following are Sub-Topics of Vitamin K2

Vitamin K2 is a Sub of the following Topic

View the Evidence:
91 Abstracts with Vitamin K2 Research

[+]

Efficacy of vitamin K2 in the prevention and treatment of postmenopausal osteoporosis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Public Health. 2022 ;10:979649. Epub 2022 Aug 11. PMID: 36033779
Article Published Date : Dec 31, 2021
Study Type : Meta Analysis
Additional Links
Substances : Vitamin K2
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

High-dose vitamin K supplementation reduces fracture incidence in postmenopausal women.Apr 01, 2009

Pubmed Data : Nutr Res. 2009 Apr;29(4):221-8. PMID: 19410972
Article Published Date : Apr 01, 2009
Study Type : Meta Analysis
Additional Links
Substances : Vitamin K, Vitamin K2
Diseases : Bone Fractures, Osteoporosis, Postmenopausal Disorders
[+]

Vitamin K1 and K2 exhibit anti-fracture activity.Dec 01, 2009

Pubmed Data : Clin Calcium. 2009 Dec;19(12):1805-14. PMID: 19949272
Article Published Date : Dec 01, 2009
Study Type : Meta Analysis
Additional Links
Substances : Vitamin K2
Diseases : Bone Fractures, Osteoporosis
[+]

A high vitamin K2 (menaquinone) intake reduces the incidence of coronary heart disease.Sep 01, 2009

Pubmed Data : Nutr Metab Cardiovasc Dis. 2009 Sep;19(7):504-10. Epub 2009 Jan 28. PMID: 19179058
Article Published Date : Sep 01, 2009
Study Type : Human Study
Additional Links
Substances : Vitamin K2, Vitamin K2: (MK-8), Vitamin K2: (MK-9), Vitamin K2: Menaquinone-7
Diseases : Coronary Artery Disease
[+]

A vitamin K2 preparation inhibits the development of liver cancer in patients with type C cirrhosis. Sep 01, 2010

Pubmed Data : Hepatogastroenterology. 2010 Sep-Oct;57(102-103):1264-7. PMID: 21410069
Article Published Date : Sep 01, 2010
Study Type : Human Study
Additional Links
Substances : Menatetrenone, Vitamin K2, Vitamin K2: Menaquinones (MK-4-14)
Diseases : Liver Cancer, Liver Cirrhosis
Pharmacological Actions : Anticarcinogenic Agents, Hepatoprotective
[+]

Adding vitamin K(2) to vitamin D(3) with calcium reduced the lifetime probability ofat least one fracture by 25%, increased discounted survival by 0.7 quality-adjusted life-years (QALYs). Mar 08, 2012

Pubmed Data : Osteoporos Int. 2012 Mar 8. Epub 2012 Mar 8. PMID: 22398856
Article Published Date : Mar 08, 2012
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : Bone Fractures
[+]

An increase in dietary intake of vitamin K is associated with a reduced risk of cardiovascular, cancer, or all-cause mortality.Apr 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr. 2014 May ;144(5):743-50. Epub 2014 Mar 19. PMID: 24647393
Article Published Date : Apr 30, 2014
Study Type : Human Study
Additional Links
Substances : Vitamin K, Vitamin K2
Diseases : All-Cause Mortality, Cancer Mortality, Cancers: All, Cardiac Mortality , Cardiovascular Diseases, Diabetes Mellitus: Type 2
Additional Keywords : All-Cause Mortality, Cancer Mortality, Cancers: All, Cardiac Mortality, Cardiovascular Diseases, Diabetes mellitus: Type 2, Risk Reduction, Vitamin K, Vitamin K2
[+]

Aterofisiol showed to be effective in reducing the amounts of cholesterol and lipids in the plaques and in reducing adverse neurological events.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2015 ;9:3877-84. Epub 2015 Jul 23. PMID: 26229448
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids, Resveratrol, Vitamin B12, Vitamin B6, Vitamin K2
Diseases : Carotid Stenosis
Pharmacological Actions : Anticholesteremic Agents, Hypolipidemic
Additional Keywords : Proanthocyanidins
[+]

Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease, cardiac mortality, aortic calcification and all-cause mortality. Nov 01, 2004

Pubmed Data : J Nutr. 2004 Nov;134(11):3100-5. PMID: 15514282
Article Published Date : Nov 01, 2004
Study Type : Human Study
Additional Links
Substances : Vitamin K, Vitamin K2, Vitamin K2: Menaquinone-7
Diseases : Aortic Calcification, Arteriosclerosis, Cardiac Mortality , Coronary Artery Disease, Mortality: All-Cause, Myocardial Infarction
Pharmacological Actions : Cardioprotective
[+]

Dietary vitamin K2 supplement improves bone status after lung and heart transplantation.Feb 27, 2010

Pubmed Data : Transplantation. 2010 Feb 27;89(4):458-64. PMID: 20177349
Article Published Date : Feb 27, 2010
Study Type : Human Study
Additional Links
Substances : Vitamin K2, Vitamin K2: Menaquinone-7
Diseases : Organ Transplantation, Organ Transplantation: Heart, Organ Transplantation: Lung, Osteoporosis
[+]

Effect of vitamin K2 and vitamin D3 on bone mineral density in children with acute lymphoblastic leukemia.Apr 26, 2021

Pubmed Data : J Pediatr Endocrinol Metab. 2021 Apr 27 ;34(4):441-447. Epub 2021 Feb 25. PMID: 33639045
Article Published Date : Apr 26, 2021
Study Type : Human Study
Additional Links
Substances : Vitamin D, Vitamin K2
Diseases : Acute lymphoblastic leukemia (ALL), Chemotherapy, Osteoporosis
Pharmacological Actions : Chemoprotective Agents, Osteoprotective
[+]

High dietary menaquinone (Vitamin K2) intake is associated with reduced coronary calcification.Apr 01, 2009

Pubmed Data : Atherosclerosis. 2009 Apr;203(2):489-93. Epub 2008 Jul 19. PMID: 18722618
Article Published Date : Apr 01, 2009
Study Type : Human Study
Additional Links
Substances : Menaquinone , Vitamin K2
Diseases : Arterial Calcification, Cardiovascular Diseases, Coronary Artery Disease
Pharmacological Actions : Cardioprotective
[+]

Improvement in menopausal symptoms with a nutritional product containing evening primrose oil, hop extract, saffron, tryptophan, vitamins B6, D3, K2, B12, and B9.Aug 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Rev Med Pharmacol Sci. 2023 Sep ;27(17):8180-8189. PMID: 37750646
Article Published Date : Aug 31, 2023
Study Type : Human Study
Additional Links
Substances : Evening Primrose Oil, Folate, Tryptophan, Vitamin B-12, Vitamin B-6, Vitamin D, Vitamin K2
Diseases : Menopausal Syndrome
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
Additional Keywords : Plant Extracts
[+]

Levels of menaquinone-7 and vitamin D are lower in those wtih hip fracture, indicating they may have a role in fracture prevention.Jan 01, 2011

Pubmed Data : Asia Pac J Clin Nutr. 2011;20(1):56-61. PMID: 21393111
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Substances : Vitamin D, Vitamin K2: Menaquinone-7
Diseases : Hip Fracture
[+]

Long-term use of MK-7 supplements improves arterial stiffness in healthy postmenopausal women, especially in women having a high arterial stiffness.Apr 30, 2015

Pubmed Data : Thromb Haemost. 2015 May ;113(5):1135-44. Epub 2015 Feb 19. PMID: 25694037
Article Published Date : Apr 30, 2015
Study Type : Human Study
Additional Links
Substances : Vitamin K2: Menaquinone-7
Diseases : Arterial Hardening: Elasticity
[+]

Menaquinone-7 (vitamin K2) supplementation increases osteocalcin carboxylation associated with improved bone quality.Oct 01, 2009

Pubmed Data : Br J Nutr. 2009 Oct;102(8):1171-8. Epub 2009 May 19. PMID: 19450370
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Substances : Vitamin K2: Menaquinone-7
Diseases : Bone Fractures, Osteoporosis
[+]

MK-7 in addition to ordinary meals could improve osteocalcin γ-carboxylation status.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2015 ;61(6):471-80. PMID: 26875489
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Vitamin K2: Menaquinone-7
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Oral consumption of vitamin K2 for 8 weeks associated with increased maximal cardiac output during exercise.Jun 30, 2017

Pubmed Data : Altern Ther Health Med. 2017 Jul ;23(4):26-32. PMID: 28646812
Article Published Date : Jun 30, 2017
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : Athletic Performance
Therapeutic Actions : Exercise
[+]

Supplementing sorafenib with vitamin K may produce synergistic therapeutic effects against hepatocellular carcinoma.Jan 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Korean J Hepatobiliary Pancreat Surg. 2015 Feb ;19(1):1-5. Epub 2015 Feb 28. PMID: 26155269
Article Published Date : Jan 31, 2015
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Chemothapeutic Synergy: Sorafenib, Significant Treatment Outcome
[+]

The consumption of vitamin K2 rich fermented soybean food products may contribute to the relatively lower fracture risk of Japanese women. Apr 01, 2001

Pubmed Data : Nutrition. 2001 Apr;17(4):315-21. PMID: 11369171
Article Published Date : Apr 01, 2001
Study Type : Human Study
Additional Links
Substances : Fermented Foods and Beverages, Natto , Soy, Vitamin K, Vitamin K2: Menaquinone-7
Diseases : Osteoporosis
Additional Keywords : Risk Reduction
[+]

There is an inverse association between the intake of menaquinones and prostate cancer.Apr 01, 2008

Pubmed Data : Am J Clin Nutr. 2008 Apr;87(4):985-92. PMID: 18400723
Article Published Date : Apr 01, 2008
Study Type : Human Study
Additional Links
Substances : Vitamin K, Vitamin K2, Vitamin K2: Menaquinones (MK-4-14)
Diseases : Prostate Cancer: Prevention
[+]

These gut-derived findings provide evidence for a regulatory role of vitamin K2 on glycemic homeostasis.May 04, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Med. 2023 May 5 ;21(1):174. Epub 2023 May 5. PMID: 37147641
Article Published Date : May 04, 2023
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance, Obesity
Pharmacological Actions : Gastrointestinal Agents, Insulin Sensitizers
[+]

These results demonstrate that vitamin K2 supplementation during COVID-19 is safe and decreases desphospho-uncarboxylated matrix gla protein.Jun 13, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Med. 2024 Jun 14 ;13(12). Epub 2024 Jun 14. PMID: 38930004
Article Published Date : Jun 13, 2024
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : Coronavirus Disease (Covid-19)
[+]

These results suggest that menaquinone-7 improves disease activity in patients with rheumatoid arthritis.Aug 14, 2015

Pubmed Data : Eur J Pharmacol. 2015 Aug 15 ;761:273-8. Epub 2015 Jun 11. PMID: 26073022
Article Published Date : Aug 14, 2015
Study Type : Human Study
Additional Links
Substances : Vitamin K2: Menaquinone-7
Diseases : C-Reactive Protein, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Matrix metalloproteinase-3 (MMP-3) inhibitor
Additional Keywords : Significant Treatment Outcome
[+]

This clinical study reported the advantageous effect of Menaquinone-7 administration on depression status in PCOS patients.Jan 25, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Womens Health. 2022 07 26 ;22(1):315. Epub 2022 Jul 26. PMID: 35883082
Article Published Date : Jan 25, 2022
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : Depression, Polycystic Ovary Syndrome
Pharmacological Actions : Antidepressive Agents
[+]

Vitamin D3 and vitamin K2 have a therapeutic effect on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.May 01, 2008

Pubmed Data : J Nutr. 2008 May;138(5):954-63. PMID: 11180916
Article Published Date : May 01, 2008
Study Type : Human Study
Additional Links
Substances : Vitamin D, Vitamin K, Vitamin K2: Menaquinone-7
Diseases : Osteoporosis
[+]

Vitamin K-induced effects on body fat and weight.Dec 31, 2017

Pubmed Data : Eur J Clin Nutr. 2018 Jan ;72(1):136-141. Epub 2017 Sep 27. PMID: 28952607
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Vitamin K2: Menaquinone-7
Diseases : Obesity
Additional Keywords : Anti-Obesity Agents
[+]

Vitamin K2 (MK-4) may be beneficial in the maintenance of bone health in postmenopausal women.Feb 01, 2009

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2009 Feb;55(1):15-21. PMID: 19352059
Article Published Date : Feb 01, 2009
Study Type : Human Study
Additional Links
Substances : Vitamin K2, Vitamin K2: (MK-4)
Diseases : Bone Fractures, Osteoporosis, Postmenopausal Disorders
[+]

Vitamin K2 administration may reduce the progression of atherosclerosis.Jul 14, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pol Arch Med Wewn. 2015 Jul 15. Epub 2015 Jul 15. PMID: 26176325
Article Published Date : Jul 14, 2015
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : Atherosclerosis
Pharmacological Actions : Anti-atherogenic
[+]

Vitamin K2 had a positive effect on bone mineral density in osteoporotic adults with cerebral palsy.Jun 13, 2017

Pubmed Data : Brain Dev. 2017 Jun 14. Epub 2017 Jun 14. PMID: 28624135
Article Published Date : Jun 13, 2017
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : Cerebral Palsy, Osteoporosis
[+]

Vitamin K2 improves disease activity in rheumatoid arthritis. Nov 05, 2012

Pubmed Data : Mod Rheumatol. 2012 Nov 6. Epub 2012 Nov 6. PMID: 23124653
Article Published Date : Nov 05, 2012
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : C-Reactive Protein, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Matrix metalloproteinase-3 (MMP-3) inhibitor
[+]

Vitamin K2 levels are lower in multiple sclerosis patients.Mar 01, 2018

Pubmed Data : Wien Klin Wochenschr. 2018 Mar 2. Epub 2018 Mar 2. PMID: 29500722
Article Published Date : Mar 01, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : Multiple Sclerosis, Vitamin K Deficiency
[+]

Vitamin K2 plus Vitamin D3 are therapeutic for the treatment of anemia and thyrombocytopenia associated wtih low/intermediate myelodysplastic syndrome. Sep 01, 2010

Pubmed Data : Leuk Res. 2010 Sep;34(9):1151-7. Epub 2010 Jun 1. PMID: 20569983
Article Published Date : Sep 01, 2010
Study Type : Human Study
Additional Links
Substances : Vitamin D, Vitamin K, Vitamin K2
Diseases : Anemia: Aplastic, Myelodysplastic Syndrome, Thrombocytopenia
[+]

Vitamin K2 status and arterial stiffness among untreated migraine patients.Nov 24, 2019

Pubmed Data : Headache. 2019 Nov 25. Epub 2019 Nov 25. PMID: 31769041
Article Published Date : Nov 24, 2019
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : Arterial Hardening: Elasticity, Vitamin K Deficiency
Pharmacological Actions : Cardioprotective
[+]

Vitamin K2 supplementation in dose of 90 µg/day performed a significant effect on reducing bone loss in postmenopausal women.Feb 13, 2020

Pubmed Data : Calcif Tissue Int. 2020 Feb 14. Epub 2020 Feb 14. PMID: 32060566
Article Published Date : Feb 13, 2020
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Risk Reduction
[+]

Vitamin K2 supplementation was associated with improvement in subclinical vitamin K deficiency and arterial stiffness.Aug 31, 2017

Pubmed Data : J Am Soc Hypertens. 2017 Sep ;11(9):589-597. Epub 2017 Jul 13. PMID: 28756183
Article Published Date : Aug 31, 2017
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : Arterial Hardening: Elasticity
[+]

Vitamin K2 treatment in combination with calcium supplementation increases bone mineral density in the treatment of postmenopausal osteoporosis.Apr 01, 2006

Pubmed Data : J Obstet Gynaecol Res. 2006 Apr;32(2):230-4. PMID: 16594930
Article Published Date : Apr 01, 2006
Study Type : Human Study
Additional Links
Substances : Vitamin K2, Vitamin K2: (MK-4)
Diseases : Osteoporosis
[+]

Vitamin MK-7 preserves trabecular bone structure at the tibia.Nov 30, 2016

Pubmed Data : Eur J Endocrinol. 2016 Dec ;175(6):541-549. Epub 2016 Sep 13. PMID: 27625301
Article Published Date : Nov 30, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin K2: Menaquinone-7
Diseases : Osteopenia
Pharmacological Actions : Osteoprotective
[+]

vitamin Vitamin (2) works synergistically with alendronate on improving both osteocalcin carboxylation and BMD of femoral neck in postmenopausal women with osteoporosis.Jan 01, 2008

Pubmed Data : J Bone Miner Metab. 2008;26(3):260-4. Epub 2008 May 11. PMID: 18470667
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : Bone Fractures, Osteoporosis
Additional Keywords : Drug Synergy
[+]

Vitamins K2 and D3 have a protective effect on prednisolone-induced loss of bone mineral density in the lumbar spine.Jan 01, 2004

Pubmed Data : Am J Kidney Dis. 2004 Jan;43(1):53-60. PMID: 14712427
Article Published Date : Jan 01, 2004
Study Type : Human Study
Additional Links
Substances : Vitamin D, Vitamin K, Vitamin K2: Menaquinone-7
Diseases : Corticosteroid-Induced Toxicity, Osteoporosis: Steroid-Induced
Additional Keywords : Drug: Prednisolone
[+]

The results of the present study suggested that vitamin K2 targets miR-133a to regulate osteogenesis.Apr 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2017 May ;15(5):2473-2480. Epub 2017 Mar 9. PMID: 28447758
Article Published Date : Apr 30, 2017
Study Type : Human In Vitro
Additional Links
Substances : Vitamin K2
Diseases : Osteonecrosis, Osteoporosis
Pharmacological Actions : MicroRNA modulator, Osteogenic
[+]

Vitamin K2 immunosuppressive effect on pediatric patients with atopic dermatitis.Nov 30, 2019

Pubmed Data : Pediatr Int. 2019 Dec ;61(12):1188-1195. Epub 2019 Dec 13. PMID: 31560147
Article Published Date : Nov 30, 2019
Study Type : Human In Vitro
Additional Links
Substances : Vitamin K2
Diseases : Atopic Dermatitis
Pharmacological Actions : Immunosuppressive Agents
[+]

Effects of vitamin K2 administration on guided bone regeneration in diabetic rats.May 13, 2024

Pubmed Data : J Periodontal Res. 2024 May 14. Epub 2024 May 14. PMID: 38742688
Article Published Date : May 13, 2024
Study Type : Animal Study
Additional Links
Substances : Vitamin K2
Diseases : Diabetic Complications
Additional Keywords : Bone Regeneration
[+]

Lactobacillus casei Zhang and vitamin K2 prevent intestinal tumorigenesis.Apr 10, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Apr 11 ;8(15):24719-24727. PMID: 28445967
Article Published Date : Apr 10, 2017
Study Type : Animal Study
Additional Links
Substances : Lactobacillus casei, Vitamin K2
Diseases : Colon Cancer
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
[+]

Menaquinone-7, a form of vitamin K2, has a stimulatory effect on bone formation in the femoral tissues of elderly female rats in vitro.Dec 01, 2002

Pubmed Data : Int J Mol Med. 2002 Dec;10(6):729-33. PMID: 12429999
Article Published Date : Dec 01, 2002
Study Type : Animal Study
Additional Links
Substances : Genistein, Vitamin K, Vitamin K2: Menaquinone-7
Diseases : Aging, Osteopenia, Osteoporosis
[+]

Menaquinone-7, a form of vitamin K2, may prevent age-related bone loss. Jan 01, 2004

Pubmed Data : Biofactors. 2004;22(1-4):5-19. PMID: 15630245
Article Published Date : Jan 01, 2004
Study Type : Animal Study
Additional Links
Substances : Vitamin K, Vitamin K2: Menaquinone-7
Diseases : Aging, Osteoporosis
[+]

Neuroprotective effect of Vitamin K2 against gut dysbiosis associated cognitive decline.Sep 30, 2023

Pubmed Data : Physiol Behav. 2023 Oct 1 ;269:114252. Epub 2023 May 29. PMID: 37257737
Article Published Date : Sep 30, 2023
Study Type : Animal Study
Additional Links
Substances : Vitamin K2
Diseases : Cognitive Decline/Dysfunction, Dysbiosis
Pharmacological Actions : Anti-Bacterial Agents, Neuroprotective Agents
[+]

Protective effect of vitamin K2 (MK-7) on acute lung injury induced by lipopolysaccharide in mice.Feb 21, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Issues Mol Biol. 2024 Feb 22 ;46(3):1700-1712. Epub 2024 Feb 22. PMID: 38534726
Article Published Date : Feb 21, 2024
Study Type : Animal Study
Additional Links
Substances : Vitamin K2
Diseases : Lipopolysaccharide-Induced Toxicity, Lung Damage
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents
[+]

Vitamin K metabolism in a rat model of chronic kidney disease.Dec 31, 2016

Pubmed Data : Am J Nephrol. 2017 ;45(1):4-13. Epub 2016 Nov 16. PMID: 27846632
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Vitamin K, Vitamin K2
Diseases : Chronic Kidney Disease (CKD), Vitamin K Deficiency
Pharmacological Actions : Renoprotective
[+]

Vitamin k2 administration could improve glycemic status in type 2 diabetic rats by induction of osteocalcin gene expression.Feb 28, 2018

Pubmed Data : Nutrition. 2018 Mar ;47:33-38. Epub 2017 Oct 26. PMID: 29429532
Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : Vitamin K2
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Gene Expression Regulation
[+]

Vitamin K2 alleviated the DSS-induced colitis.Feb 02, 2023

Pubmed Data : Int J Mol Sci. 2023 Feb 3 ;24(3). Epub 2023 Feb 3. PMID: 36769323
Article Published Date : Feb 02, 2023
Study Type : Animal Study
Additional Links
Substances : Vitamin K2
Diseases : Colitis, Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Vitamin K2 and selenium improved metabolic profile, markers of cardiovascular health and atherosclerosis in dyslipidemic rabbits.Sep 30, 2023

Pubmed Data : Biol Trace Elem Res. 2023 Oct ;201(10):4758-4768. Epub 2023 Jan 25. PMID: 36696048
Article Published Date : Sep 30, 2023
Study Type : Animal Study
Additional Links
Substances : Selenium, Vitamin K2
Diseases : Cardiovascular Diseases, Dyslipidemias
Pharmacological Actions : Antioxidants
Additional Keywords : Natural Substance Synergy
[+]

Vitamin K2 can inhibit calcification of aortic intima in mice.Dec 31, 2016

Pubmed Data : Vascular. 2017 Jan 1:1708538117713395. Epub 2017 Jan 1. PMID: 28587577
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Vitamin K2
Diseases : Arterial Calcification, Atherosclerosis
Pharmacological Actions : Anti-atherogenic
[+]

Vitamin K2 improves anxiety and depression in rats with metabolic syndrome.Nov 30, 2016

Pubmed Data : Folia Med (Plovdiv). 2016 Dec 1 ;58(4):264-272. PMID: 28068285
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Vitamin K2
Diseases : Anxiety, Depression, Metabolic Syndrome X
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
[+]

Vitamin K2 may be a potential therapeutic agent in the treatment of prostate cancer.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2013 ;2013:287358. Epub 2013 Aug 24. PMID: 24062781
Article Published Date : Dec 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin K2
Diseases : Prostate Cancer
Pharmacological Actions : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Apoptotic, NF-kappaB Inhibitor
Additional Keywords : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Apoptotic, NF-kappaB Inhibitor, prostate cancer, Vitamin K2
[+]

Vitamin K2 prevents lymphoma in drosophila.Dec 05, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Dec 6 ;7(1):17047. Epub 2017 Dec 6. PMID: 29213118
Article Published Date : Dec 05, 2017
Study Type : Insect Study
Additional Links
Substances : Vitamin K2
Diseases : Lymphoma
Pharmacological Actions : Chemopreventive
[+]

Vitamin K2 protects against aluminium chloride-mediated neurodegeneration.Sep 30, 2023

Pubmed Data : Inflammopharmacology. 2023 Oct ;31(5):2675-2684. Epub 2023 Jul 21. PMID: 37477796
Article Published Date : Sep 30, 2023
Study Type : Animal Study
Additional Links
Substances : Vitamin K2
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Brain-derived neurotrophic factor modulator, Neuroprotective Agents
Problem Substances : Aluminum Chloride
[+]

Vitamin K2 protects mice against non-alcoholic fatty liver disease induced by high-fat diet.Feb 05, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2024 Feb 6 ;14(1):3075. Epub 2024 Feb 6. PMID: 38321064
Article Published Date : Feb 05, 2024
Study Type : Animal Study
Additional Links
Substances : Vitamin K2
Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Hepatoprotective
[+]

Vitamin K2 regression aortic calcification induced by warfarin.Sep 04, 2016

Pubmed Data : Eur J Pharmacol. 2016 Sep 5 ;786:10-18. Epub 2016 May 19. PMID: 27212383
Article Published Date : Sep 04, 2016
Study Type : Animal Study
Additional Links
Substances : Vitamin K2
Diseases : Aortic Calcification
Pharmacological Actions : Anti-Apoptotic
Problem Substances : Warfarin
[+]

Vitamin K2-MK-7 improves nitric oxide-dependent endothelial function in ApoE/LDLR-/- mice.Nov 30, 2019

Pubmed Data : Vascul Pharmacol. 2019 Nov - Dec;122-123:106581. Epub 2019 Aug 14. PMID: 31421222
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : Vitamin K2: Menaquinone-7
Diseases : Atherosclerosis, Endothelial Dysfunction
Pharmacological Actions : Anti-atherogenic
[+]

Vitamins K2 plus vitamin D combination could be a novel therapeutic strategy in treating diabetes-associated osteoporosis.Nov 14, 2015

Pubmed Data : Eur J Pharmacol. 2015 Nov 15 ;767:30-40. Epub 2015 Oct 8. PMID: 26452518
Article Published Date : Nov 14, 2015
Study Type : Animal Study
Additional Links
Substances : Vitamin D, Vitamin K2
Diseases : Diabetic Complications, Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Natural Substance Synergy
[+]

Vitamin D3 and K2 and their potential contribution to reducing the COVID-19 mortality rate.Aug 05, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Infect Dis. 2020 Aug 6 ;99:286-290. Epub 2020 Aug 6. PMID: 32768697
Article Published Date : Aug 05, 2020
Study Type : Review
Additional Links
Substances : Magnesium, Vitamin D, Vitamin K2
Diseases : Coronavirus Infection
Additional Keywords : Risk Reduction
[+]

Vitamin K2 works synergistically with acyclic retinoid to suppress growth in human hepatocellular carcinoma cells.Mar 01, 2007

Pubmed Data : Cancer Sci. 2007 Mar ;98(3):431-7. PMID: 17270033
Article Published Date : Mar 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K2
Diseases : Liver Cancer
Pharmacological Actions : Antineoplastic Agents
Additional Keywords : Drug Synergy
[+]

A review of the effects of vitamin K2 on type 2 diabetes mellitus.Jan 31, 2018

Pubmed Data : Diabetes Res Clin Pract. 2018 Feb ;136:39-51. Epub 2017 Dec 2. PMID: 29196151
Article Published Date : Jan 31, 2018
Study Type : Review
Additional Links
Substances : Vitamin K2
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Anti-Inflammatory Agents
[+]

A review of the regulation of bone remodelling by vitamin K2.Oct 31, 2017

Pubmed Data : Oral Dis. 2017 Nov ;23(8):1021-1028. Epub 2017 Apr 5. PMID: 27976475
Article Published Date : Oct 31, 2017
Study Type : Review
Additional Links
Substances : Vitamin K2
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Clinical trials have shown that patients with osteoporosis, cardiovascular diseases and cancer can benefit from vitamin K2 supplement.Aug 02, 2015

Pubmed Data : Ugeskr Laeger. 2015 Aug 3 ;177(32):V12140700. PMID: 26321585
Article Published Date : Aug 02, 2015
Study Type : Review
Additional Links
Substances : Vitamin K2
Diseases : Cancers: All, Cardiovascular Diseases, Inflammation, Osteoporosis
Additional Keywords : Cancers: All, Cardiovascular Diseases, Inflammation, Osteoporosis, Vitamin K2
[+]

Divergent effects of vitamins K1 and K2 on triple negative breast cancer cells.Mar 18, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2019 Mar 19 ;10(23):2292-2305. Epub 2019 Mar 19. PMID: 31040920
Article Published Date : Mar 18, 2019
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K2
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative
[+]

Mechanisms of PKC-mediated enhancement of HIF-1α activity and its inhibition by vitamin K2 in hepatocellular carcinoma cells.Feb 25, 2019

Pubmed Data : Int J Mol Sci. 2019 Feb 26 ;20(5). Epub 2019 Feb 26. PMID: 30813635
Article Published Date : Feb 25, 2019
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K2
Diseases : Hypoxia, Liver Cancer
Pharmacological Actions : Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
[+]

Menaquinone-7, a form of vitamin K2, has an inhibitory effect on the bone-resorbing factors-induced bone resorption in elderly female rat femoral tissues in vitro.May 01, 2008

Pubmed Data : Exp Parasitol. 2008 May;119(1):74-9. Epub 2007 Dec 28. PMID: 12708750
Article Published Date : May 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K, Vitamin K2: Menaquinone-7
Diseases : Osteoporosis
[+]

Protective effects of vitamin K2 on 6-OHDA-induced apoptosis in PC12 cells through modulation bax and caspase-3 activation.Nov 30, 2019

Pubmed Data : Mol Biol Rep. 2019 Dec ;46(6):5777-5783. Epub 2019 Aug 7. PMID: 31392537
Article Published Date : Nov 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K2
Diseases : Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Research indicates that vitamin K2 intake reduces coronary heart disease events.Oct 01, 2010

Pubmed Data : Maturitas. 2010 Oct;67(2):121-8. Epub 2010 Jun 17. PMID: 20850029
Article Published Date : Oct 01, 2010
Study Type : Review
Additional Links
Substances : Vitamin K2
Diseases : Coronary Artery Disease
[+]

Supplementation with phytonadione (Vitamin K1) and menaquinone (Vitamin K2) , particularly menaquinone-4, is associated with increased BMD and reduced fracture incidence. Oct 01, 2008

Pubmed Data : Clin Calcium. 2008 Oct;18(10):1476-82. PMID: 18830045
Article Published Date : Oct 01, 2008
Study Type : Review
Additional Links
Substances : Vitamin K, Vitamin K2, Vitamin K2: (MK-4)
Diseases : Bone Fractures, Osteoporosis
[+]

The combination of vitamin K2 and cotylenin A has therapeutic value in the treatment of acute myeloid leukemia.Jul 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Oncol. 2015 Aug ;47(2):473-80. Epub 2015 Jun 4. PMID: 26046133
Article Published Date : Jul 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K2
Diseases : Acute Myeloid Leukemia
Pharmacological Actions : Antiproliferative , Cell cycle arrest
Additional Keywords : Gene Expression Regulation
[+]

The intake of natto, an excellent source of vitamin K2, may reduce bone fracture risk. Sep 01, 2009

Pubmed Data : Clin Calcium. 2009 Sep;19(9):1362-9. PMID: 19721210
Article Published Date : Sep 01, 2009
Study Type : Review
Additional Links
Substances : Natto , Vitamin K2, Vitamin K2: Menaquinone-7
Diseases : Bone Fractures
[+]

This study shows the real-time effects of VK derivatives on breast cancer cells and suggests that dietary factors may be an important consideration for patients.Jul 31, 2015

Pubmed Data : Nutr Res. 2015 Aug ;35(8):736-43. Epub 2015 May 30. PMID: 26082424
Article Published Date : Jul 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K2
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative
Additional Keywords : Dose Response
[+]

Vitamin D, unopposed by sufficient vitamin K (and possibly vitamin A), may cause hypercalcemia and other metabolic imbalances.Jan 01, 2007

Pubmed Data : Med Hypotheses. 2007;68(5):1026-34. Epub 2006 Dec 4. PMID: 17145139
Article Published Date : Jan 01, 2007
Study Type : Commentary
Additional Links
Substances : Vitamin A, Vitamin D, Vitamin K, Vitamin K2: Menaquinone-7
Diseases : Hypercalcemia
Additional Keywords : Nutrient Interdependence
[+]

Vitamin K has been shown to suppress the growth of liver cancer cells.Oct 31, 2015

Pubmed Data : Clin Calcium. 2015 Nov ;25(11):1645-51. PMID: 26503869
Article Published Date : Oct 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K2
Diseases : Liver Cancer
Pharmacological Actions : Antineoplastic Agents, Apoptotic, Chemotherapeutic
Additional Keywords : Antineoplastic Agents, Apoptotic, Chemotherapeutic, liver cancer, Natural Substance/Drug Synergy, Vitamin K2
[+]

Vitamin K supplementation may be useful for a number of chronic conditions.Dec 31, 2016

Pubmed Data : J Nutr Metab. 2017 ;2017:6254836. Epub 2017 Jun 18. PMID: 28698808
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Substances : Vitamin K, Vitamin K2
Diseases : Arterial Calcification, Arthritis, Cancers: All, Diabetes Mellitus: Type 2, Osteoporosis
[+]

Vitamin K(2) serves as a mitochondrial electron carrier, helping to maintain normal ATP production in mitochondrial dysfunction.Jun 07, 2012

Pubmed Data : Science. 2012 Jun 8 ;336(6086):1306-10. Epub 2012 May 10. PMID: 22582012
Article Published Date : Jun 07, 2012
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K2
Diseases : Mitochondrial Diseases, Mitochondrial Dysfunction
[+]

Vitamin K2 ameliorates osteoarthritis by suppressing ferroptosis and extracellular matrix degradation through activation GPX4's dual functions.May 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2024 Jun ;175:116697. Epub 2024 May 17. PMID: 38759289
Article Published Date : May 31, 2024
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K2
Diseases : Osteoarthritis
Pharmacological Actions : Chondroprotective, Osteoprotective
[+]

Vitamin K2 augments 5-fluorouracil-induced growth inhibition of human hepatocellular carcinoma cells by inhibiting NF-κB activation.Jan 01, 2011

Pubmed Data : Oncol Rep. 2011 Jan;25(1):159-66. PMID: 21109972
Article Published Date : Jan 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K, Vitamin K2
Diseases : Liver Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Chemosensitizer, NF-kappaB Inhibitor
Additional Keywords : Drug: 5-flourouracil, Drug Synergy
[+]

Vitamin K2 can be an interesting strategy in benefitting bone and vascular health.Dec 11, 2017

Pubmed Data : Crit Rev Food Sci Nutr. 2017 Dec 12 ;57(18):3959-3970. PMID: 27437760
Article Published Date : Dec 11, 2017
Study Type : Review
Additional Links
Substances : Vitamin K, Vitamin K2
Diseases : Arterial Calcification, Osteoporosis
[+]

Vitamin K2 could be a promising agent for the prevention and treatment of glucocorticoids induced osteoporosis and osteonecrosis.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2017 Jan ;39(1):160-166. Epub 2016 Dec 1. PMID: 27909721
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K2
Diseases : Osteonecrosis, Osteoporosis
[+]

Vitamin K2 enhances the tumor suppressive effects of 1,25(OH)2D3 in triple negative breast cancer cells.Jun 30, 2023

Pubmed Data : J Steroid Biochem Mol Biol. 2023 Jul ;231:106307. Epub 2023 Apr 6. PMID: 37030416
Article Published Date : Jun 30, 2023
Study Type : In Vitro Study
Additional Links
Substances : Vitamin D, Vitamin K2
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative , Cell cycle arrest
[+]

Vitamin K2 has a dual mode of action with therapeutic potential in fracture prevention and proper bone mineral density. Jan 01, 2011

Pubmed Data : Int J Mol Med. 2011 Jan;27(1):3-14. Epub 2010 Nov 11. PMID: 21072493
Article Published Date : Jan 01, 2011
Study Type : Review
Additional Links
Substances : Vitamin K2, Vitamin K2: Menaquinone-7
Diseases : Bone Fractures, Osteoporosis
Pharmacological Actions : NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Vitamin K2 has immunomodulatory activities.Feb 28, 2018

Pubmed Data : Oral Dis. 2018 Mar ;24(1-2):67-71. PMID: 29480629
Article Published Date : Feb 28, 2018
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K2
Diseases : Osteoporosis
Pharmacological Actions : Immunomodulatory
[+]

Vitamin K2 induces apoptosis in bladder cancer cells.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(8):e0161886. Epub 2016 Aug 29. PMID: 27570977
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K2
Diseases : Bladder Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Apoptotic, bladder cancer, Cancer, Vitamin K, Vitamin K2
[+]

Vitamin K2 induces non-apoptotic cell death along with autophagosome formation in breast cancer cell lines.Oct 16, 2019

Pubmed Data : Breast Cancer. 2019 Oct 17. Epub 2019 Oct 17. PMID: 31625014
Article Published Date : Oct 16, 2019
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K2
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Apoptotic
[+]

Vitamin K2 targets castration-resistant prostate cancer cell-line by activating apoptosis signalling.Feb 08, 2018

Pubmed Data : Food Chem Toxicol. 2018 Feb 9 ;115:218-227. Epub 2018 Feb 9. PMID: 29432837
Article Published Date : Feb 08, 2018
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K2
Diseases : Prostate Cancer
Pharmacological Actions : Apoptotic
[+]

Vitamin K2-derived compounds inhibit growth in radioresistant cancer cells.Dec 31, 2009

Pubmed Data : Kobe J Med Sci. 2010 ;56(2):E38-49. Epub 2010 Sep 28. PMID: 21063145
Article Published Date : Dec 31, 2009
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K2
Diseases : Cancers: Radiation-Resistant
Pharmacological Actions : Antiproliferative , NF-kappaB Inhibitor, Radiosensitizer
[+]

Vtamin K2 may improve bone quality in type 2 diabetes.Mar 01, 2011

Pubmed Data : Nutr Rev. 2011 Mar;69(3):162-7. Epub 2011 Feb 14. PMID: 21348880
Article Published Date : Mar 01, 2011
Study Type : Review
Additional Links
Substances : Vitamin K2
Diseases : Diabetes: Bone Quality & Density, Diabetes Mellitus: Type 2, Osteoporosis

Copyright: lisaanfisa / 123RF Stock Photo

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