Vitexins

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60 Diseases Researched for Vitexins
NameACCKFocus
Osteoarthritis27Locked
Inflammation46Locked
Oxidative Stress46Locked
Alzheimer's Disease34Locked
Epilepsy24Locked
High Fat Diet24Locked
Lipopolysaccharide-Induced Toxicity34Locked
Liver Damage24Locked
Brain Inflammation 23Locked
Colorectal Cancer23Locked
Liver Cancer23Locked
Acrylamide-induced toxicity12Locked
Alcoholic Liver Disease12Locked
Anxiety12Locked
Asthma12Locked
Cerebral Ischemia22Locked
Chemotherapy-Induced Toxicity: Doxorubicin12Locked
Colitis12Locked
Diabetic Complications12Locked
Hyperalgesia12Locked
Infertility: Male12Locked
Ischemia12Locked
Lung Injury: Acute12Locked
Memory Disorders: Drug-Induced12Locked
Middle Cerebral Artery Occlusion (MCAO)12Locked
Mitochondrial Dysfunction 12Locked
Myocardial Ischemia12Locked
Nasopharyngeal Cancer12Locked
Nonalcoholic fatty liver disease (NAFLD)12Locked
Obesity12Locked
Parkinson's Disease12Locked
Postoperative Recovery12Locked
Pre-Eclampsia12Locked
Sepsis12Locked
Surgery: Anesthesiology12Locked
Wound Healing12Locked
Bone Diseases11Locked
Brain Ischemia11Locked
Brain: Oxidative Stress11Locked
Cancers: All11Locked
Carcinoma: Non-Small-Cell Lung11Locked
Cholesterol: Oxidation11Locked
Endothelial Dysfunction11Locked
Glioblastoma11Locked
Glioma11Locked
Hepatitis A 11Locked
Hepatitis B 11Locked
Hepatitis C11Locked
Herpes Simplex Virus Type 111Locked
Influenza11Locked
Kidney Cancer11Locked
Lung Cancer11Locked
Memory Disorders11Locked
Myocardial Infarction11Locked
Neurodegenerative Diseases11Locked
Neutrophils: Elevated11Locked
Pseudomonas aeruginosa11Locked
Rotavirus Infections11Locked
Skin Diseases11Locked
Stroke: Neonatal11Locked
45 Pharmacological Actions Researched for Vitexins
NameACCKFocus
Anti-Inflammatory Agents1731Locked
Neuroprotective Agents1217Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor716Locked
Antioxidants1115Locked
Interleukin-6 Downregulation513Locked
Anti-Apoptotic912Locked
Interleukin-1 beta downregulation512Locked
Apoptotic79Locked
NF-kappaB Inhibitor59Locked
Hepatoprotective48Locked
Antiproliferative 67Locked
Cardioprotective35Locked
Matrix Metalloproteinase-13 (MMP-13) Inhibitor15Locked
Matrix metalloproteinase-3 (MMP-3) inhibitor15Locked
Nrf2 activation45Locked
Autophagy Inhibitors24Locked
Heme oxygenase-1 up-regulation23Locked
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor23Locked
Analgesics12Locked
Anti-Anxiety Agents12Locked
Anticonvulsants12Locked
Antinoceceptive 12Locked
Bcl-2 protein down-regulation12Locked
Chemoprotective Agents12Locked
Chondroprotective12Locked
Fertility Agents: Male12Locked
Interleukin-10 upregulation12Locked
Interleukin-8 downregulation12Locked
Malondialdehyde Down-regulation12Locked
MicroRNA modulator12Locked
Nitric Oxide Inhibitor12Locked
Superoxide Dismutase Up-regulation12Locked
Vascular Endothelial Growth Factor Inhibitors12Locked
Anti-Bacterial Agents11Locked
Anti-metastatic11Locked
Antineoplastic Agents11Locked
Antiviral Agents11Locked
Cell cycle arrest11Locked
Chemopreventive11Locked
Chemosensitizer11Locked
Chemotherapeutic11Locked
Interleukin-17 downregulation11Locked
Pancreato Protective Agents11Locked
Radiosensitizer11Locked
STAT3 Inhibitor11Locked

View the Evidence:
63 Abstracts with Vitexins Research

[+]

Vitexin alleviates interleukin-1β induced inflammatory responses in chondrocytes from osteoarthritis patients.May 03, 2019

Pubmed Data : Scand J Immunol. 2019 May 4:e12773. Epub 2019 May 4. PMID: 31055848
Article Published Date : May 03, 2019
Study Type : Human In Vitro
Additional Links
Substances : Vitexins
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Matrix metalloproteinase-3 (MMP-3) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The protective effect of vitexinin septic encephalopathy by reducing leukocyte-endothelial adhesion and inflammatory response.Jun 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Palliat Med. 2020 Jul ;9(4):2079-2089. Epub 2020 Jul 14. PMID: 32692224
Article Published Date : Jun 30, 2020
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Interleukin-8 downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Vitexin ameliorates chronic stress plub high fat diet-induced nonalcoholic fatty liver disease by inhibiting inflammation.Sep 04, 2020

Pubmed Data : Eur J Pharmacol. 2020 Sep 5 ;882:173264. Epub 2020 Jun 13. PMID: 32544504
Article Published Date : Sep 04, 2020
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, NF-kappaB Inhibitor
[+]

Evaluation of wound healing effect of chitosan-based gel formulation containing vitexin.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi Pharm J. 2020 Jan ;28(1):87-94. Epub 2019 Nov 20. PMID: 31933527
Article Published Date : Dec 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Wound Healing
[+]

Hepatoprotective role of vitexin against cadmium-induced liver damage.Apr 10, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2022 Apr 11 ;150:112934. Epub 2022 Apr 11. PMID: 35421786
Article Published Date : Apr 10, 2022
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Cadmium
[+]

Protective effects of vitexin on cadmium-induced renal toxicity.Sep 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi J Biol Sci. 2021 Oct ;28(10):5860-5864. Epub 2021 Jun 18. PMID: 34588901
Article Published Date : Sep 30, 2021
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Kidney Damage: Chemically-Induced
Pharmacological Actions : Renoprotective
Problem Substances : Cadmium
[+]

The presence of flavonoids, such as Vitexin derivatives in beet stalks and leaves can help the liver damage induced by high fat diet.Jul 04, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Jul 5 ;10(7). Epub 2018 Jul 5. PMID: 29976910
Article Published Date : Jul 04, 2018
Study Type : Animal Study
Additional Links
Substances : Beet, Vitexins
Diseases : High Fat Diet, Liver Damage, Oxidative Stress
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

The results show that vitexin acts as a neuroprotective agent.Sep 13, 2020

Pubmed Data : J Biochem Mol Toxicol. 2020 Sep 14:e22632. Epub 2020 Sep 14. PMID: 32926499
Article Published Date : Sep 13, 2020
Study Type : Transgenic Animal Study
Additional Links
Substances : Vitexins
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

These findings suggest that vitexin ameliorates sexual dysfunction and fertility impairments in male diabetic mice.Jan 04, 2019

Pubmed Data : Chem Biol Interact. 2019 Jan 5 ;297:119-129. Epub 2018 Oct 23. PMID: 30365938
Article Published Date : Jan 04, 2019
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Diabetic Complications, Infertility: Male
Pharmacological Actions : Fertility Agents: Male
[+]

These results suggest a new protective mechanism of vitexin for ischemic heart disease treatment.Mar 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2020 Apr ;124:109849. Epub 2020 Jan 20. PMID: 31972356
Article Published Date : Mar 31, 2020
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Mitochondrial Dysfunction , Myocardial Ischemia
Pharmacological Actions : Cardioprotective
[+]

This is the first report that confers vitexin meditated multi-faceted protective attribute in mitigation of allergic asthma.Jan 31, 2022

Pubmed Data : Phytomedicine. 2022 Feb ;96:153902. Epub 2021 Dec 21. PMID: 35026520
Article Published Date : Jan 31, 2022
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Asthma
Pharmacological Actions : Anti-Asthmatic Agents, Immunomodulatory
[+]

Vitexin alleviates ER-stress-activated apoptosis and the related inflammation in chondrocytes.Nov 13, 2018

Pubmed Data : Food Funct. 2018 Nov 14 ;9(11):5740-5749. PMID: 30321247
Article Published Date : Nov 13, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Inflammation, Osteoarthritis
Pharmacological Actions : Anti-Apoptotic, Chondroprotective, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Vitexin ameliorates high fat diet-induced obesity.Mar 31, 2019

Pubmed Data : Food Funct. 2019 Apr 1 ;10(4):1940-1947. Epub 2019 Mar 15. PMID: 30874277
Article Published Date : Mar 31, 2019
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : High Fat Diet, Obesity
Additional Keywords : Anti-Obesity Agents
[+]

Vitexin ameliorates preeclampsia phenotypes by inhibiting TFPI-2 and HIF-1α/VEGF.Nov 30, 2019

Pubmed Data : Drug Dev Res. 2019 Dec ;80(8):1120-1127. Epub 2019 Sep 4. PMID: 31486114
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Pre-Eclampsia
Pharmacological Actions : Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Vascular Endothelial Growth Factor Inhibitors
[+]

Vitexin attenuates acute doxorubicin cardiotoxicity.Aug 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2016 Sep ;12(3):1879-1884. Epub 2016 Jul 13. PMID: 27588105
Article Published Date : Aug 31, 2016
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Chemoprotective Agents
[+]

Vitexin attenuates autoimmune hepatitis.Feb 14, 2022

Pubmed Data : Eur J Pharmacol. 2022 Feb 15 ;917:174720. Epub 2021 Dec 23. PMID: 34953801
Article Published Date : Feb 14, 2022
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Hepatitis: Autoimmune
Pharmacological Actions : Hepatoprotective
[+]

Vitexin attenuates lipopolysaccharide-induced acute lung injury by controlling the Nrf2 pathway.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2018 ;13(4):e0196405. Epub 2018 Apr 25. PMID: 29694408
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, Nrf2 activation
[+]

Vitexin attenuates non-alcoholic fatty liver disease lipid accumulation.Feb 28, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2022 Mar 1 ;45(3):260-267. Epub 2022 Jan 15. PMID: 35034930
Article Published Date : Feb 28, 2022
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Autophagy Up-regulation, Hepatoprotective, Hypolipidemic
[+]

Vitexin could be regarded as a potent therapeutic agent for the treatment of liver cancer.Dec 19, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2016 Dec 20 ;7(51):84520-84532. PMID: 27588401
Article Published Date : Dec 19, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, Autophagy Inhibitors
[+]

Vitexin displays preclinical antitumor activity by suppressing NF-κB signaling in nasopharyngeal carcinoma.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Onco Targets Ther. 2019 ;12:4461-4468. Epub 2019 Jun 5. PMID: 31239714
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Nasopharyngeal Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative , Bcl-2 protein down-regulation, NF-kappaB Inhibitor
[+]

Vitexin has a protective effect against ethanol-induced liver damage.Apr 14, 2020

Pubmed Data : Eur J Pharmacol. 2020 Apr 15 ;873:173007. Epub 2020 Feb 8. PMID: 32045602
Article Published Date : Apr 14, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Alcoholic Liver Disease
Pharmacological Actions : Hepatoprotective
[+]

Vitexin has protective effects against isoflurane-induced neurotoxicity by targeting miR-409 and the AMPK/GSK3β pathway.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Clin Exp Med. 2020 Jan ;29(1):135-145. PMID: 32011832
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Memory Disorders: Drug-Induced, Surgery: Anesthesiology
Pharmacological Actions : Anti-Apoptotic, Interleukin-6 Downregulation, MicroRNA modulator, Neuroprotective Agents, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Vitexin improves cerebral ischemia‑reperfusion injury.Nov 25, 2022

Pubmed Data : Neurochem Res. 2022 Nov 26. Epub 2022 Nov 26. PMID: 36435955
Article Published Date : Nov 25, 2022
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Cerebral Ischemia
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, Nrf2 activation
[+]

Vitexin improves immunosuppression, oxidative stress, and phosphorylation of PI3K/Akt signal pathway in cyclophosphamide treated mice.May 03, 2022

Pubmed Data : Eur J Pharmacol. 2022 May 4 ;925:174999. Epub 2022 May 4. PMID: 35525311
Article Published Date : May 03, 2022
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions : Antioxidants, Immunomodulatory
[+]

Vitexin induces apoptosis by suppressing autophagy in multi-drug resistant colorectal cancer cells.Jan 08, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2018 Jan 9 ;9(3):3278-3291. Epub 2017 Dec 4. PMID: 29423046
Article Published Date : Jan 08, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Colorectal Cancer
Pharmacological Actions : Apoptotic
[+]

Vitexin inhibits acrylamide-induced neuroinflammation and improves behavioral changes.May 30, 2019

Pubmed Data : Neurotoxicol Teratol. 2019 May 31 ;74:106811. Epub 2019 May 31. PMID: 31158445
Article Published Date : May 30, 2019
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Acrylamide-induced toxicity, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Problem Substances : Acrylamide
[+]

Vitexin inhibits APEX1 to counteract the flow-induced endothelial inflammation.Jan 29, 2021

Pubmed Data : Proc Natl Acad Sci U S A. 2021 11 30 ;118(48). PMID: 34810252
Article Published Date : Jan 29, 2021
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Atherosclerosis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Vitexin inhibits inflammation in murine ovalbumin-induced allergic asthma.Dec 31, 2017

Pubmed Data : Biomed Pharmacother. 2018 Jan ;97:143-151. Epub 2017 Nov 6. PMID: 29091859
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Asthma, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Vitexin is a promising therapeutic candidate treatment for epilepsy in the immature brain.Jun 19, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroinflammation. 2018 Jun 20 ;15(1):186. Epub 2018 Jun 20. PMID: 29925377
Article Published Date : Jun 19, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Epilepsy, Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Vitexin may be useful for the control of postoperative pain.Jan 13, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2016 Jan 14 ;6:19266. Epub 2016 Jan 14. PMID: 26763934
Article Published Date : Jan 13, 2016
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Hyperalgesia, Postoperative Recovery
Pharmacological Actions : Analgesics, Antinoceceptive
[+]

Vitexin possess hepatoprotective activities against colitis-induced liver injury.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2020 Jan ;121:109683. Epub 2019 Nov 24. PMID: 31810123
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Colitis, Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Vitexin possesses anticonvulsant and anxiolytic-like effects in murine animal models. Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:1181. Epub 2020 Aug 11. PMID: 32848784
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Anxiety, Epilepsy
Pharmacological Actions : Anti-Anxiety Agents, Anticonvulsants
[+]

Vitexin protects against dextran sodium sulfate-induced colitis.Sep 27, 2022

Pubmed Data : J Agric Food Chem. 2022 Sep 28 ;70(38):12041-12054. Epub 2022 Sep 20. PMID: 36124900
Article Published Date : Sep 27, 2022
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Colitis, Inflammation, Ulcerative Colitis
Pharmacological Actions : Gastrointestinal Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Vitexin protects dopaminergic neurons in MPTP-induced Parkinson's disease.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2018 ;12:565-573. Epub 2018 Mar 16. PMID: 29588573
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Vitexin regulates angiogenesis and osteogenesis in ovariectomy-induced osteoporosis.Dec 19, 2022

Pubmed Data : J Agric Food Chem. 2022 Dec 20. Epub 2022 Dec 20. PMID: 36538589
Article Published Date : Dec 19, 2022
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Vitexin reverses the autophagy dysfunction to attenuate MCAO-induced cerebral ischemic stroke.Feb 28, 2018

Pubmed Data : Biomed Pharmacother. 2018 Mar ;99:583-590. Epub 2018 Feb 20. PMID: 29710456
Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : Vitexins
Diseases : Middle Cerebral Artery Occlusion (MCAO)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Autophagy Inhibitors, Interleukin-10 upregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

A brief review on the neuroprotective mechanisms of vitexin.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2018 ;2018:4785089. Epub 2018 Dec 5. PMID: 30627560
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Substances : Vitexins
Diseases : Inflammation, Neurodegenerative Diseases
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Antiviral properties of flavonoids and delivery strategies. Aug 20, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Aug 21 ;12(9). Epub 2020 Aug 21. PMID: 32825564
Article Published Date : Aug 20, 2020
Study Type : Review
Additional Links
Substances : Apigenin, Naringenin , Quercetin, Rutin, Vitexins
Diseases : Hepatitis A , Hepatitis B , Hepatitis C, Herpes Simplex Virus Type 1, Influenza, Rotavirus Infections
Pharmacological Actions : Antiviral Agents
[+]

Attenuation of Pseudomonas aeruginosa biofilm formation by vitexin.Mar 21, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2016 Mar 22 ;6:23347. Epub 2016 Mar 22. PMID: 27000525
Article Published Date : Mar 21, 2016
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Pseudomonas aeruginosa
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Natural Substances Versus Drugs
[+]

Chemopreventive and anticancer activity of flavonoids and its possibility for clinical use by combining with conventional chemotherapeutic agents.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Cancer Res. 2019 ;9(8):1517-1535. Epub 2019 Aug 1. PMID: 31497340
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Apigenin, Cyanidin, Delphinidin, Flavonoids, Kaempferol, Luteolin, Quercetin, Vitexins, Wogonin
Diseases : Cancers: All
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Antiproliferative , Apoptotic, Chemopreventive, Chemosensitizer, Chemotherapeutic
[+]

Multitasking bamboo leaf-derived compounds in prevention of infectious, inflammatory, atherosclerotic, metabolic, and neuropsychiatric diseases.Feb 16, 2022

Pubmed Data : Pharmacol Ther. 2022 Feb 17 ;235:108159. Epub 2022 Feb 17. PMID: 35183589
Article Published Date : Feb 16, 2022
Study Type : Review
Additional Links
Substances : Bamboo, Vitexins
Diseases : Atherosclerosis, Inflammation, Metabolic Diseases, Neurologic Disorders, Periodontal Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Gastrointestinal Agents
[+]

Neuroprotective effects of vitexin against isoflurane-induced neurotoxicity.Nov 30, 2016

Pubmed Data : Mol Med Rep. 2016 Dec ;14(6):5607-5613. Epub 2016 Nov 16. PMID: 27878303
Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Brain: Oxidative Stress, Brain Inflammation
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Possible epigenetic role of vitexin in regulating neuroinflammation in Alzheimer's disease. Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Immunol Res. 2020 ;2020:9469210. Epub 2020 Mar 9. PMID: 32258178
Article Published Date : Dec 31, 2019
Study Type : Review
Additional Links
Substances : Vitexins
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Pre-treatment with vitexin protects against neonatal hypoxic-ischemic brain injury.Apr 10, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Apr 11 ;8(15):25513-25524. PMID: 28424420
Article Published Date : Apr 10, 2017
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Brain Ischemia, Stroke: Neonatal
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Protective effect of hawthorn vitexin on the ethanol-injured DNA of BRL-3A hepatocytes.Dec 16, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicine (Baltimore). 2021 Dec 17 ;100(50):e28228. PMID: 34918685
Article Published Date : Dec 16, 2021
Study Type : In Vitro Study
Additional Links
Substances : Hawthorn, Vitexins
Diseases : Alcohol Toxicity , DNA damage, Liver Damage, Oxidative Stress
Pharmacological Actions : Antioxidants, Hepatoprotective, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
[+]

Quercetin or vitexin may be considered as a therapeutic strategy for treating patients with neutrophil-mediated inflammatory diseases.May 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacopuncture. 2017 Jun ;20(2):127-131. Epub 2017 Jun 30. PMID: 30087790
Article Published Date : May 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Quercetin, Vitexins
Diseases : Inflammation, Neutrophils: Elevated
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Review of the effects of vitexin in oxidative stress-related diseases.May 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2020 Jun ;8(6):2569-2580. Epub 2020 Apr 14. PMID: 32566174
Article Published Date : May 31, 2020
Study Type : Review
Additional Links
Substances : Vitexins
Diseases : Cerebral Ischemia, Memory Disorders, Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Vitexin alleviates lipopolysaccharide‑induced islet cell injury by inhibiting HMGB1 release.Feb 28, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2017 Mar ;15(3):1079-1086. Epub 2017 Jan 12. PMID: 28098903
Article Published Date : Feb 28, 2017
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Vitexin alleviates ox-LDL-mediated endothelial injury by inducing autophagy via AMPK signaling activation.Dec 31, 2016

Pubmed Data : Mol Immunol. 2017 05 ;85:214-221. Epub 2017 Mar 10. PMID: 28288411
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Cholesterol: Oxidation, Endothelial Dysfunction, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Vitexin can act as a potential blocker of the STAT3 signaling cascade and mitigate the survival as well as invasion of HCC cells.Jul 31, 2020

Pubmed Data : Biochimie. 2020 Aug ;175:58-68. Epub 2020 May 21. PMID: 32445654
Article Published Date : Jul 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Liver Cancer
Pharmacological Actions : Anti-metastatic, Apoptotic, STAT3 Inhibitor
Additional Keywords : Chemothapeutic Synergy: Sorafenib, Chemotherapeutic Synergy: Doxorubicin
[+]

Vitexin confers HSF-1 mediated autophagic cell death by activating JNK and ApoL1 in colorectal carcinoma cells.Dec 21, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Dec 22 ;8(68):112426-112441. Epub 2017 Aug 10. PMID: 29348836
Article Published Date : Dec 21, 2017
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Colorectal Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Vitexin could be used as a potential therapeutic agent for the treatment of NSCLC.Feb 22, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Res. 2019 Feb 23 ;52(1):7. Epub 2019 Feb 23. PMID: 30797236
Article Published Date : Feb 22, 2019
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
[+]

Vitexin enhances the radiotherapy sensitization of hyperbaric oxygen on glioma.Oct 31, 2019

Pubmed Data : Clin Transl Oncol. 2019 Nov 1. Epub 2019 Nov 1. PMID: 31677055
Article Published Date : Oct 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Glioma
Pharmacological Actions : Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Radiosensitizer
[+]

Vitexin inhibits gastric cancer growth and metastasis.Nov 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Gastric Cancer. 2021 Dec ;21(4):439-456. Epub 2021 Dec 31. PMID: 35079445
Article Published Date : Nov 30, 2021
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Gastric Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative
[+]

Vitexin may in the future be used as a therapeutic agent for treatment of malignant glioblastoma.Feb 28, 2018

Pubmed Data : Mol Med Rep. 2018 Mar ;17(3):4599-4604. Epub 2018 Jan 8. PMID: 29328424
Article Published Date : Feb 28, 2018
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Glioblastoma
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Vitexin mitigates Staphylococcus aureus-induced mastitis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2022 ;2022:7977433. Epub 2022 Jun 27. PMID: 35795861
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Mastitis, Staphylococcus aureus infection
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

vitexin offers neuroprotection against Alzheimer's disease.Jul 31, 2018

Pubmed Data : Toxicol In Vitro. 2018 Aug ;50:160-171. Epub 2018 Mar 12. PMID: 29545167
Article Published Date : Jul 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Alzheimer's Disease
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, Nrf2 activation
[+]

Vitexin protected melanocytes from oxidative stress by activating MAPK-Nrf2/ARE signaling pathway.Nov 02, 2020

Pubmed Data : Immunopharmacol Immunotoxicol. 2020 Nov 3:1-10. Epub 2020 Nov 3. PMID: 33045867
Article Published Date : Nov 02, 2020
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Skin Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-17 downregulation, Interleukin-1 beta downregulation, Nrf2 activation
[+]

Vitexin protects against ischemia/reperfusion-induced brain endothelial permeability.Jun 14, 2019

Pubmed Data : Eur J Pharmacol. 2019 Jun 15 ;853:210-219. Epub 2019 Mar 12. PMID: 30876978
Article Published Date : Jun 14, 2019
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Cerebral Ischemia
Pharmacological Actions : Neuroprotective Agents
[+]

Vitexin protects isoproterenol induced post myocardial injury by modulating hipposignaling and ER stress responses.Jan 04, 2018

Pubmed Data : Biochem Biophys Res Commun. 2018 02 5 ;496(2):731-737. PMID: 29406244
Article Published Date : Jan 04, 2018
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Myocardial Infarction
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Cardioprotective
[+]

Vitexin restores pancreatic β-cell function and insulin signaling through Nrf2 and NF-κB signaling pathways.Sep 23, 2020

Pubmed Data : Eur J Pharmacol. 2020 Sep 24 ;888:173606. Epub 2020 Sep 24. PMID: 32980348
Article Published Date : Sep 23, 2020
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Pharmacological Actions : Antioxidants, Nrf2 activation, Pancreato Protective Agents
[+]

Vitexin suppresses RANKL-induced osteoclastogenesis and prevents lipopolysaccharide (LPS)-induced osteolysis.Feb 20, 2019

Pubmed Data : J Cell Physiol. 2019 Feb 21. Epub 2019 Feb 21. PMID: 30793311
Article Published Date : Feb 20, 2019
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Bone Diseases, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Vitexin suppresses renal cell carcinoma by regulating mTOR pathways.Jul 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Transl Androl Urol. 2020 Aug ;9(4):1700-1711. PMID: 32944531
Article Published Date : Jul 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Kidney Cancer
Pharmacological Actions : Antiproliferative

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