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12 Diseases Researched for Wheat Bran

Name	AC	CK	Focus
Colonic Spasm	1	10
Diverticular Disease	1	10
Gallstones	1	10
Hyperinsulinism	1	10
Insulin Resistance	1	10
Colon Cancer	3	4
Oxidative Stress	2	4
Bladder Dysfunction	1	2
Bladder Outlet Obstruction	1	2
Pesticide Toxicity	1	2
Colorectal Cancer	1	1
Colorectal Tumors	1	1

8 Pharmacological Actions Researched for Wheat Bran

Name	AC	CK	Focus
Glucagon Like peptide 1 (GLP-1) Up-regulation	1	10
Chemopreventive	3	4
Anticarcinogenic Agents	2	3
Antiproliferative	2	3
Apoptotic	2	3
Interleukin-1 beta downregulation	1	2
Tumor Necrosis Factor (TNF) Alpha Inhibitor	1	2
Cell cycle arrest	1	1

Research Articles 10
Cumulative Knowledge Score 16
Overall Research Rating GOOD

View the Evidence:
10 Abstracts with Wheat Bran Research

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[+]

Wheat bran consumption prevents cholesterol gallstones. Aug 24, 1984

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Pubmed Data : Dtsch Med Wochenschr. 1984 Aug 24;109(34):1284-8. PMID: 6088204

Article Published Date : Aug 24, 1984

Study Type : Human Study

Additional Links

Substances : Fiber, Wheat Bran

Diseases : Gallstones

[+]

Wheat bran relieves the symptoms of diverticular disease. Feb 21, 1976

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Pubmed Data : Br Med J. 1976 Feb 21;1(6007):425-8. PMID: 766894

Article Published Date : Feb 21, 1976

Study Type : Human Study

Additional Links

Substances : Fiber, Wheat Bran

Diseases : Colonic Spasm, Diverticular Disease

[+]

Wheat fiber supplementation increases GLP-1 secretion and improves colonic fermentation by-products in hyperinsulinemic patients. Jan 01, 2010

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Pubmed Data : Br J Nutr. 2010 Jan;103(1):82-90. Epub 2009 Aug 7. PMID: 19664300

Article Published Date : Jan 01, 2010

Study Type : Human Study

Additional Links

Substances : Fiber, Wheat Bran

Diseases : Hyperinsulinism, Insulin Resistance

Pharmacological Actions : Glucagon Like peptide 1 (GLP-1) Up-regulation

[+]

A proprietary blend of herbs suppresses bladder oxidative stress and inflammation in a rat model of partial bladder outlet obstruction.Jul 01, 2009

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Pubmed Data : J Urol. 2009 Jul;182(1):382-90. Epub 2009 May 17. PMID: 19447421

Article Published Date : Jul 01, 2009

Study Type : Animal Study

Additional Links

Substances : Aspen, Horsetail, Pipsisssewa, Pulsatilla pratensis, Wheat Bran

Diseases : Bladder Dysfunction , Bladder Outlet Obstruction, Oxidative Stress

Pharmacological Actions : Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Wheat bran has a protective effect against diquat toxicity in rats. Jul 01, 2007

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Pubmed Data : Biosci Biotechnol Biochem. 2007 Jul;71(7):1621-5. Epub 2007 Jul 7. PMID: 17617720

Article Published Date : Jul 01, 2007

Study Type : Animal Study

Additional Links

Substances : Fiber, Wheat Bran

Diseases : Oxidative Stress, Pesticide Toxicity

[+]

Wheat bran increases programmed cell death and inhibits proliferation in an animal model of colon cancer.Jan 01, 2009

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Pubmed Data : BMC Cancer. 2009;9:414. Epub 2009 Nov 30. PMID: 10485439

Article Published Date : Jan 01, 2009

Study Type : Animal Study

Additional Links

Substances : Fiber, Wheat Bran

Diseases : Colon Cancer

Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Apoptotic, Chemopreventive

[+]

Both wheat (Triticum aestivum) bran arabinoxylans and gut flora-mediated fermentation products protect human colon cells from chemically-induced adverse changes.Mar 22, 2006

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Pubmed Data : J Agric Food Chem. 2006 Mar 22;54(6):2088-95. PMID: 16536580

Article Published Date : Mar 22, 2006

Study Type : In Vitro Study

Additional Links

Substances : Arabinoxylans, Fermented Foods and Beverages, Fiber, Wheat: Fermented, Wheat Bran

Diseases : Colon Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Chemopreventive

[+]

Exogenous application of β-sitosterol mediated growth and yield improvement in water-stressed wheat involves up-regulated antioxidant system.Oct 31, 2019

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Pubmed Data : J Plant Res. 2019 Nov ;132(6):881-901. Epub 2019 Oct 12. PMID: 31606785

Article Published Date : Oct 31, 2019

Study Type : Plant Study

Additional Links

Substances : Beta Sitosterol, Wheat Bran

[+]

Lignans are involved in the antitumor activity of wheat bran in colon cancer cells.Mar 01, 2005

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Pubmed Data : J Nutr. 2005 Mar;135(3):598-602. PMID: 15735100

Article Published Date : Mar 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Fiber, Lignans, Wheat Bran

Diseases : Colon Cancer

Pharmacological Actions : Anticarcinogenic Agents, Cell cycle arrest, Chemopreventive

[+]

Wheat bran may reduce incidence of large colorectal adenomas.Jan 25, 1999

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Pubmed Data : Am J Med. 1999 Jan 25;106(1A):38S-42S. PMID: 10089114

Article Published Date : Jan 25, 1999

Study Type : Review

Additional Links

Substances : Wheat Bran

Diseases : Colorectal Cancer, Colorectal Tumors

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